Genome wide association study identifies KCNMA1 contributing to human obesity

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Genome wide association study identifies KCNMA1 contributing to human obesity. / Jiao, Hong; Arner, Peter; Hoffstedt, Johan; Brodin, David; Dubern, Beatrice; Czernichow, Sébastien; van't Hooft, Ferdinand; Axelsson, Tomas; Pedersen, Oluf; Hansen, Torben; Sørensen, Thorkild I A; Hebebrand, Johannes; Kere, Juha; Dahlman-Wright, Karin; Hamsten, Anders; Clement, Karine; Dahlman, Ingrid.

In: B M C Medical Genomics, Vol. 4, 2011, p. 51.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Jiao, H, Arner, P, Hoffstedt, J, Brodin, D, Dubern, B, Czernichow, S, van't Hooft, F, Axelsson, T, Pedersen, O, Hansen, T, Sørensen, TIA, Hebebrand, J, Kere, J, Dahlman-Wright, K, Hamsten, A, Clement, K & Dahlman, I 2011, 'Genome wide association study identifies KCNMA1 contributing to human obesity', B M C Medical Genomics, vol. 4, pp. 51. https://doi.org/10.1186/1755-8794-4-51

APA

Jiao, H., Arner, P., Hoffstedt, J., Brodin, D., Dubern, B., Czernichow, S., van't Hooft, F., Axelsson, T., Pedersen, O., Hansen, T., Sørensen, T. I. A., Hebebrand, J., Kere, J., Dahlman-Wright, K., Hamsten, A., Clement, K., & Dahlman, I. (2011). Genome wide association study identifies KCNMA1 contributing to human obesity. B M C Medical Genomics, 4, 51. https://doi.org/10.1186/1755-8794-4-51

Vancouver

Jiao H, Arner P, Hoffstedt J, Brodin D, Dubern B, Czernichow S et al. Genome wide association study identifies KCNMA1 contributing to human obesity. B M C Medical Genomics. 2011;4:51. https://doi.org/10.1186/1755-8794-4-51

Author

Jiao, Hong ; Arner, Peter ; Hoffstedt, Johan ; Brodin, David ; Dubern, Beatrice ; Czernichow, Sébastien ; van't Hooft, Ferdinand ; Axelsson, Tomas ; Pedersen, Oluf ; Hansen, Torben ; Sørensen, Thorkild I A ; Hebebrand, Johannes ; Kere, Juha ; Dahlman-Wright, Karin ; Hamsten, Anders ; Clement, Karine ; Dahlman, Ingrid. / Genome wide association study identifies KCNMA1 contributing to human obesity. In: B M C Medical Genomics. 2011 ; Vol. 4. pp. 51.

Bibtex

@article{33ce63f792924953ab49ab491cb89387,
title = "Genome wide association study identifies KCNMA1 contributing to human obesity",
abstract = "Recent genome-wide association (GWA) analyses have identified common single nucleotide polymorphisms (SNPs) that are associated with obesity. However, the reported genetic variation in obesity explains only a minor fraction of the total genetic variation expected to be present in the population. Thus many genetic variants controlling obesity remain to be identified. The aim of this study was to use GWA followed by multiple stepwise validations to identify additional genes associated with obesity.",
keywords = "Alleles, Body Mass Index, Case-Control Studies, Cohort Studies, Female, France, Genetic Predisposition to Disease, Genome, Human, Genome-Wide Association Study, Germany, Humans, Large-Conductance Calcium-Activated Potassium Channel alpha Subunits, Male, Middle Aged, Obesity, Morbid, Polymorphism, Single Nucleotide, Sweden",
author = "Hong Jiao and Peter Arner and Johan Hoffstedt and David Brodin and Beatrice Dubern and S{\'e}bastien Czernichow and {van't Hooft}, Ferdinand and Tomas Axelsson and Oluf Pedersen and Torben Hansen and S{\o}rensen, {Thorkild I A} and Johannes Hebebrand and Juha Kere and Karin Dahlman-Wright and Anders Hamsten and Karine Clement and Ingrid Dahlman",
year = "2011",
doi = "10.1186/1755-8794-4-51",
language = "English",
volume = "4",
pages = "51",
journal = "BMC Medical Genomics",
issn = "1755-8794",
publisher = "BioMed Central Ltd.",

}

RIS

TY - JOUR

T1 - Genome wide association study identifies KCNMA1 contributing to human obesity

AU - Jiao, Hong

AU - Arner, Peter

AU - Hoffstedt, Johan

AU - Brodin, David

AU - Dubern, Beatrice

AU - Czernichow, Sébastien

AU - van't Hooft, Ferdinand

AU - Axelsson, Tomas

AU - Pedersen, Oluf

AU - Hansen, Torben

AU - Sørensen, Thorkild I A

AU - Hebebrand, Johannes

AU - Kere, Juha

AU - Dahlman-Wright, Karin

AU - Hamsten, Anders

AU - Clement, Karine

AU - Dahlman, Ingrid

PY - 2011

Y1 - 2011

N2 - Recent genome-wide association (GWA) analyses have identified common single nucleotide polymorphisms (SNPs) that are associated with obesity. However, the reported genetic variation in obesity explains only a minor fraction of the total genetic variation expected to be present in the population. Thus many genetic variants controlling obesity remain to be identified. The aim of this study was to use GWA followed by multiple stepwise validations to identify additional genes associated with obesity.

AB - Recent genome-wide association (GWA) analyses have identified common single nucleotide polymorphisms (SNPs) that are associated with obesity. However, the reported genetic variation in obesity explains only a minor fraction of the total genetic variation expected to be present in the population. Thus many genetic variants controlling obesity remain to be identified. The aim of this study was to use GWA followed by multiple stepwise validations to identify additional genes associated with obesity.

KW - Alleles

KW - Body Mass Index

KW - Case-Control Studies

KW - Cohort Studies

KW - Female

KW - France

KW - Genetic Predisposition to Disease

KW - Genome, Human

KW - Genome-Wide Association Study

KW - Germany

KW - Humans

KW - Large-Conductance Calcium-Activated Potassium Channel alpha Subunits

KW - Male

KW - Middle Aged

KW - Obesity, Morbid

KW - Polymorphism, Single Nucleotide

KW - Sweden

U2 - 10.1186/1755-8794-4-51

DO - 10.1186/1755-8794-4-51

M3 - Journal article

C2 - 21708048

VL - 4

SP - 51

JO - BMC Medical Genomics

JF - BMC Medical Genomics

SN - 1755-8794

ER -

ID: 35314425