Low-grade inflammation in young adults exposed to intrauterine hyperglycemia

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Low-grade inflammation in young adults exposed to intrauterine hyperglycemia. / Kelstrup, Louise; Clausen, Tine Dalsgaard; Mathiesen, Elisabeth R; Hansen, Torben; Damm, Peter.

In: Diabetes Research and Clinical Practice, Vol. 97, No. 2, 2012, p. 322-330.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Kelstrup, L, Clausen, TD, Mathiesen, ER, Hansen, T & Damm, P 2012, 'Low-grade inflammation in young adults exposed to intrauterine hyperglycemia', Diabetes Research and Clinical Practice, vol. 97, no. 2, pp. 322-330. https://doi.org/10.1016/j.diabres.2012.04.023

APA

Kelstrup, L., Clausen, T. D., Mathiesen, E. R., Hansen, T., & Damm, P. (2012). Low-grade inflammation in young adults exposed to intrauterine hyperglycemia. Diabetes Research and Clinical Practice, 97(2), 322-330. https://doi.org/10.1016/j.diabres.2012.04.023

Vancouver

Kelstrup L, Clausen TD, Mathiesen ER, Hansen T, Damm P. Low-grade inflammation in young adults exposed to intrauterine hyperglycemia. Diabetes Research and Clinical Practice. 2012;97(2):322-330. https://doi.org/10.1016/j.diabres.2012.04.023

Author

Kelstrup, Louise ; Clausen, Tine Dalsgaard ; Mathiesen, Elisabeth R ; Hansen, Torben ; Damm, Peter. / Low-grade inflammation in young adults exposed to intrauterine hyperglycemia. In: Diabetes Research and Clinical Practice. 2012 ; Vol. 97, No. 2. pp. 322-330.

Bibtex

@article{9a8677a9bb4940ee847a4b6c58adc698,
title = "Low-grade inflammation in young adults exposed to intrauterine hyperglycemia",
abstract = "AIM: To investigate associations between fetal exposure to intrauterine hyperglycemia and plasma concentrations of interleukin-6 (IL-6) and high sensitivity C-reactive protein (hs-CRP) in adult offspring. METHOD: We studied 597 offspring, aged 18-27years, from four different groups concerning exposure to intrauterine hyperglycemia and genetic predisposition to type 2 diabetes (offspring of women with: gestational diabetes mellitus (GDM), risk factors for GDM but normal glucose tolerance, type 1 diabetes and women from the background population, respectively). The participants were characterized by fasting plasma levels of IL-6 and hs-CRP, a 75g oral glucose tolerance test and anthropometric measurements. RESULTS: No association between intrauterine exposure to hyperglycemia and levels of IL-6 and hs-CRP in the offspring was found. In contrast maternal overweight (body mass index =25kg/m(2)) was positively associated with levels of both IL-6 and hs-CRP (p for both=0.003). Offspring who had already developed overweight or conditions of abnormal glucose tolerance were characterized by higher levels of IL-6 and hs-CRP compared with the remaining offspring (all p",
author = "Louise Kelstrup and Clausen, {Tine Dalsgaard} and Mathiesen, {Elisabeth R} and Torben Hansen and Peter Damm",
note = "Copyright {\textcopyright} 2012 Elsevier Ireland Ltd. All rights reserved.",
year = "2012",
doi = "10.1016/j.diabres.2012.04.023",
language = "English",
volume = "97",
pages = "322--330",
journal = "Diabetes Research and Clinical Practice",
issn = "0168-8227",
publisher = "Elsevier Ireland Ltd",
number = "2",

}

RIS

TY - JOUR

T1 - Low-grade inflammation in young adults exposed to intrauterine hyperglycemia

AU - Kelstrup, Louise

AU - Clausen, Tine Dalsgaard

AU - Mathiesen, Elisabeth R

AU - Hansen, Torben

AU - Damm, Peter

N1 - Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

PY - 2012

Y1 - 2012

N2 - AIM: To investigate associations between fetal exposure to intrauterine hyperglycemia and plasma concentrations of interleukin-6 (IL-6) and high sensitivity C-reactive protein (hs-CRP) in adult offspring. METHOD: We studied 597 offspring, aged 18-27years, from four different groups concerning exposure to intrauterine hyperglycemia and genetic predisposition to type 2 diabetes (offspring of women with: gestational diabetes mellitus (GDM), risk factors for GDM but normal glucose tolerance, type 1 diabetes and women from the background population, respectively). The participants were characterized by fasting plasma levels of IL-6 and hs-CRP, a 75g oral glucose tolerance test and anthropometric measurements. RESULTS: No association between intrauterine exposure to hyperglycemia and levels of IL-6 and hs-CRP in the offspring was found. In contrast maternal overweight (body mass index =25kg/m(2)) was positively associated with levels of both IL-6 and hs-CRP (p for both=0.003). Offspring who had already developed overweight or conditions of abnormal glucose tolerance were characterized by higher levels of IL-6 and hs-CRP compared with the remaining offspring (all p

AB - AIM: To investigate associations between fetal exposure to intrauterine hyperglycemia and plasma concentrations of interleukin-6 (IL-6) and high sensitivity C-reactive protein (hs-CRP) in adult offspring. METHOD: We studied 597 offspring, aged 18-27years, from four different groups concerning exposure to intrauterine hyperglycemia and genetic predisposition to type 2 diabetes (offspring of women with: gestational diabetes mellitus (GDM), risk factors for GDM but normal glucose tolerance, type 1 diabetes and women from the background population, respectively). The participants were characterized by fasting plasma levels of IL-6 and hs-CRP, a 75g oral glucose tolerance test and anthropometric measurements. RESULTS: No association between intrauterine exposure to hyperglycemia and levels of IL-6 and hs-CRP in the offspring was found. In contrast maternal overweight (body mass index =25kg/m(2)) was positively associated with levels of both IL-6 and hs-CRP (p for both=0.003). Offspring who had already developed overweight or conditions of abnormal glucose tolerance were characterized by higher levels of IL-6 and hs-CRP compared with the remaining offspring (all p

U2 - 10.1016/j.diabres.2012.04.023

DO - 10.1016/j.diabres.2012.04.023

M3 - Journal article

C2 - 22622155

VL - 97

SP - 322

EP - 330

JO - Diabetes Research and Clinical Practice

JF - Diabetes Research and Clinical Practice

SN - 0168-8227

IS - 2

ER -

ID: 38334704