Replication and meta-analysis of common variants identifies a genome-wide significant locus in migraine
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Replication and meta-analysis of common variants identifies a genome-wide significant locus in migraine. / Esserlind, A-L; Christensen, A F; Le, H; Kirchmann, M; Hauge, A W; Toyserkani, N M; Hansen, Torben; Grarup, Niels; Werge, T; Steinberg, S; Bettella, F; Stefansson, H; Olesen, J.
In: European Journal of Neurology, Vol. 20, No. 5, 05.2013, p. 765-772.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Replication and meta-analysis of common variants identifies a genome-wide significant locus in migraine
AU - Esserlind, A-L
AU - Christensen, A F
AU - Le, H
AU - Kirchmann, M
AU - Hauge, A W
AU - Toyserkani, N M
AU - Hansen, Torben
AU - Grarup, Niels
AU - Werge, T
AU - Steinberg, S
AU - Bettella, F
AU - Stefansson, H
AU - Olesen, J
N1 - © 2013 The Author(s) European Journal of Neurology © 2013 EFNS.
PY - 2013/5
Y1 - 2013/5
N2 - Genetic factors contribute to the aetiology of the prevalent form of migraine without aura (MO) and migraine with typical aura (MTA). Due to the complex inheritance of MO and MTA, the genetic background is still not fully established. In a population-based genome-wide association study by Chasman et al. (Nat Genet 2011: 43: 695-698), three common variants were found to confer risk of migraine at a genome-wide significant level (P <5 × 10(-8) ). We aimed to evaluate the top association single nucleotide polymorphisms (SNPs) from the discovery set by Chasman et al. in a primarily clinic-based Danish and Icelandic cohort.
AB - Genetic factors contribute to the aetiology of the prevalent form of migraine without aura (MO) and migraine with typical aura (MTA). Due to the complex inheritance of MO and MTA, the genetic background is still not fully established. In a population-based genome-wide association study by Chasman et al. (Nat Genet 2011: 43: 695-698), three common variants were found to confer risk of migraine at a genome-wide significant level (P <5 × 10(-8) ). We aimed to evaluate the top association single nucleotide polymorphisms (SNPs) from the discovery set by Chasman et al. in a primarily clinic-based Danish and Icelandic cohort.
U2 - 10.1111/ene.12055
DO - 10.1111/ene.12055
M3 - Journal article
C2 - 23294458
VL - 20
SP - 765
EP - 772
JO - European Journal of Neurology
JF - European Journal of Neurology
SN - 1351-5101
IS - 5
ER -
ID: 48610525