Studies of association of AGPAT6 variants with type 2 diabetes and related metabolic phenotypes in 12,068 Danes

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Studies of association of AGPAT6 variants with type 2 diabetes and related metabolic phenotypes in 12,068 Danes. / Snogdal, Lena Sønder; Grarup, Niels; Banasik, Karina; Wod, Mette; Jørgensen, Torben; Witte, Daniel R; Lauritzen, Torsten; Nielsen, Aneta Aleksandra; Brandslund, Ivan; Christensen, Cramer; Pedersen, Oluf; Yderstræde, Knud Bonnet; Beck-Nielsen, Henning; Henriksen, Jan Erik; Hansen, Torben; Højlund, Kurt.

In: BMC Medical Genetics, Vol. 14, No. 1, 25.10.2013, p. 113.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Snogdal, LS, Grarup, N, Banasik, K, Wod, M, Jørgensen, T, Witte, DR, Lauritzen, T, Nielsen, AA, Brandslund, I, Christensen, C, Pedersen, O, Yderstræde, KB, Beck-Nielsen, H, Henriksen, JE, Hansen, T & Højlund, K 2013, 'Studies of association of AGPAT6 variants with type 2 diabetes and related metabolic phenotypes in 12,068 Danes', BMC Medical Genetics, vol. 14, no. 1, pp. 113. https://doi.org/10.1186/1471-2350-14-113

APA

Snogdal, L. S., Grarup, N., Banasik, K., Wod, M., Jørgensen, T., Witte, D. R., Lauritzen, T., Nielsen, A. A., Brandslund, I., Christensen, C., Pedersen, O., Yderstræde, K. B., Beck-Nielsen, H., Henriksen, J. E., Hansen, T., & Højlund, K. (2013). Studies of association of AGPAT6 variants with type 2 diabetes and related metabolic phenotypes in 12,068 Danes. BMC Medical Genetics, 14(1), 113. https://doi.org/10.1186/1471-2350-14-113

Vancouver

Snogdal LS, Grarup N, Banasik K, Wod M, Jørgensen T, Witte DR et al. Studies of association of AGPAT6 variants with type 2 diabetes and related metabolic phenotypes in 12,068 Danes. BMC Medical Genetics. 2013 Oct 25;14(1):113. https://doi.org/10.1186/1471-2350-14-113

Author

Snogdal, Lena Sønder ; Grarup, Niels ; Banasik, Karina ; Wod, Mette ; Jørgensen, Torben ; Witte, Daniel R ; Lauritzen, Torsten ; Nielsen, Aneta Aleksandra ; Brandslund, Ivan ; Christensen, Cramer ; Pedersen, Oluf ; Yderstræde, Knud Bonnet ; Beck-Nielsen, Henning ; Henriksen, Jan Erik ; Hansen, Torben ; Højlund, Kurt. / Studies of association of AGPAT6 variants with type 2 diabetes and related metabolic phenotypes in 12,068 Danes. In: BMC Medical Genetics. 2013 ; Vol. 14, No. 1. pp. 113.

Bibtex

@article{bde0339a3fe94b41b8e88c0579f9f1f6,
title = "Studies of association of AGPAT6 variants with type 2 diabetes and related metabolic phenotypes in 12,068 Danes",
abstract = "Type 2 diabetes, obesity and insulin resistance are characterized by hypertriglyceridemia and ectopic accumulation of lipids in liver and skeletal muscle. AGPAT6 encodes a novel glycerol-3 phosphate acyltransferase, GPAT4, which catalyzes the first step in the de novo triglyceride synthesis. AGPAT6-deficient mice show lower weight and resistance to diet- and genetically induced obesity. Here, we examined whether common or low-frequency variants in AGPAT6 associate with type 2 diabetes or related metabolic traits in a Danish population.",
author = "Snogdal, {Lena S{\o}nder} and Niels Grarup and Karina Banasik and Mette Wod and Torben J{\o}rgensen and Witte, {Daniel R} and Torsten Lauritzen and Nielsen, {Aneta Aleksandra} and Ivan Brandslund and Cramer Christensen and Oluf Pedersen and Yderstr{\ae}de, {Knud Bonnet} and Henning Beck-Nielsen and Henriksen, {Jan Erik} and Torben Hansen and Kurt H{\o}jlund",
year = "2013",
month = oct,
day = "25",
doi = "10.1186/1471-2350-14-113",
language = "English",
volume = "14",
pages = "113",
journal = "B M C Medical Genetics",
issn = "1471-2350",
publisher = "BioMed Central Ltd.",
number = "1",

}

RIS

TY - JOUR

T1 - Studies of association of AGPAT6 variants with type 2 diabetes and related metabolic phenotypes in 12,068 Danes

AU - Snogdal, Lena Sønder

AU - Grarup, Niels

AU - Banasik, Karina

AU - Wod, Mette

AU - Jørgensen, Torben

AU - Witte, Daniel R

AU - Lauritzen, Torsten

AU - Nielsen, Aneta Aleksandra

AU - Brandslund, Ivan

AU - Christensen, Cramer

AU - Pedersen, Oluf

AU - Yderstræde, Knud Bonnet

AU - Beck-Nielsen, Henning

AU - Henriksen, Jan Erik

AU - Hansen, Torben

AU - Højlund, Kurt

PY - 2013/10/25

Y1 - 2013/10/25

N2 - Type 2 diabetes, obesity and insulin resistance are characterized by hypertriglyceridemia and ectopic accumulation of lipids in liver and skeletal muscle. AGPAT6 encodes a novel glycerol-3 phosphate acyltransferase, GPAT4, which catalyzes the first step in the de novo triglyceride synthesis. AGPAT6-deficient mice show lower weight and resistance to diet- and genetically induced obesity. Here, we examined whether common or low-frequency variants in AGPAT6 associate with type 2 diabetes or related metabolic traits in a Danish population.

AB - Type 2 diabetes, obesity and insulin resistance are characterized by hypertriglyceridemia and ectopic accumulation of lipids in liver and skeletal muscle. AGPAT6 encodes a novel glycerol-3 phosphate acyltransferase, GPAT4, which catalyzes the first step in the de novo triglyceride synthesis. AGPAT6-deficient mice show lower weight and resistance to diet- and genetically induced obesity. Here, we examined whether common or low-frequency variants in AGPAT6 associate with type 2 diabetes or related metabolic traits in a Danish population.

U2 - 10.1186/1471-2350-14-113

DO - 10.1186/1471-2350-14-113

M3 - Journal article

C2 - 24156295

VL - 14

SP - 113

JO - B M C Medical Genetics

JF - B M C Medical Genetics

SN - 1471-2350

IS - 1

ER -

ID: 66819335