The effect of FOXA2 rs1209523 on glucose-related phenotypes and risk of type 2 diabetes in Danish individuals
Research output: Contribution to journal › Journal article › Research › peer-review
Standard
The effect of FOXA2 rs1209523 on glucose-related phenotypes and risk of type 2 diabetes in Danish individuals. / Banasik, Karina; Hollensted, Mette; Andersson, Ehm; Sparsø, Thomas; Sandbaek, Annelli; Lauritzen, Torsten; Jørgensen, Torben; Witte, Daniel R; Pedersen, Oluf; Hansen, Torben.
In: B M C Medical Genetics, Vol. 13, 2012, p. 10.Research output: Contribution to journal › Journal article › Research › peer-review
Harvard
APA
Vancouver
Author
Bibtex
}
RIS
TY - JOUR
T1 - The effect of FOXA2 rs1209523 on glucose-related phenotypes and risk of type 2 diabetes in Danish individuals
AU - Banasik, Karina
AU - Hollensted, Mette
AU - Andersson, Ehm
AU - Sparsø, Thomas
AU - Sandbaek, Annelli
AU - Lauritzen, Torsten
AU - Jørgensen, Torben
AU - Witte, Daniel R
AU - Pedersen, Oluf
AU - Hansen, Torben
PY - 2012
Y1 - 2012
N2 - Variations within the FOXA family have been studied for a putative contribution to the risk of type 2 diabetes (T2D), and recently the minor T-allele of FOXA2 rs1209523 was reported to associate with decreased fasting plasma glucose levels in a study using a weighted false discovery rate control procedure to enhance the statistical power of genome wide association studies in detecting associations between low-frequency variants and a given trait.Thus, the primary aim of this study was to investigate whether the minor T-allele of rs1205923 in FOXA2 associated with 1) decreased fasting plasma glucose and 2) a lower risk of developing T2D. Secondly, we investigated whether rs1205923 in FOXA2 associated with other glucose-related phenotypes.
AB - Variations within the FOXA family have been studied for a putative contribution to the risk of type 2 diabetes (T2D), and recently the minor T-allele of FOXA2 rs1209523 was reported to associate with decreased fasting plasma glucose levels in a study using a weighted false discovery rate control procedure to enhance the statistical power of genome wide association studies in detecting associations between low-frequency variants and a given trait.Thus, the primary aim of this study was to investigate whether the minor T-allele of rs1205923 in FOXA2 associated with 1) decreased fasting plasma glucose and 2) a lower risk of developing T2D. Secondly, we investigated whether rs1205923 in FOXA2 associated with other glucose-related phenotypes.
U2 - 10.1186/1471-2350-13-10
DO - 10.1186/1471-2350-13-10
M3 - Journal article
C2 - 22325233
VL - 13
SP - 10
JO - B M C Medical Genetics
JF - B M C Medical Genetics
SN - 1471-2350
ER -
ID: 38334903