Variants at DGKB/TMEM195, ADRA2A, GLIS3 and C2CD4B loci are associated with reduced glucose-stimulated beta cell function in middle-aged Danish people

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Variants at DGKB/TMEM195, ADRA2A, GLIS3 and C2CD4B loci are associated with reduced glucose-stimulated beta cell function in middle-aged Danish people. / Boesgaard, T W; Grarup, N; Jørgensen, Torben; Borch-Johnsen, Knut; Hansen, T; Pedersen, Oluf; Meta-Analysis of Glucose and Insulin-Related Trait Consortium (MAGIC).

In: Diabetologia, Vol. 53, No. 8, 01.08.2010, p. 1647-55.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Boesgaard, TW, Grarup, N, Jørgensen, T, Borch-Johnsen, K, Hansen, T, Pedersen, O & Meta-Analysis of Glucose and Insulin-Related Trait Consortium (MAGIC) 2010, 'Variants at DGKB/TMEM195, ADRA2A, GLIS3 and C2CD4B loci are associated with reduced glucose-stimulated beta cell function in middle-aged Danish people', Diabetologia, vol. 53, no. 8, pp. 1647-55. https://doi.org/10.1007/s00125-010-1753-5

APA

Boesgaard, T. W., Grarup, N., Jørgensen, T., Borch-Johnsen, K., Hansen, T., Pedersen, O., & Meta-Analysis of Glucose and Insulin-Related Trait Consortium (MAGIC) (2010). Variants at DGKB/TMEM195, ADRA2A, GLIS3 and C2CD4B loci are associated with reduced glucose-stimulated beta cell function in middle-aged Danish people. Diabetologia, 53(8), 1647-55. https://doi.org/10.1007/s00125-010-1753-5

Vancouver

Boesgaard TW, Grarup N, Jørgensen T, Borch-Johnsen K, Hansen T, Pedersen O et al. Variants at DGKB/TMEM195, ADRA2A, GLIS3 and C2CD4B loci are associated with reduced glucose-stimulated beta cell function in middle-aged Danish people. Diabetologia. 2010 Aug 1;53(8):1647-55. https://doi.org/10.1007/s00125-010-1753-5

Author

Boesgaard, T W ; Grarup, N ; Jørgensen, Torben ; Borch-Johnsen, Knut ; Hansen, T ; Pedersen, Oluf ; Meta-Analysis of Glucose and Insulin-Related Trait Consortium (MAGIC). / Variants at DGKB/TMEM195, ADRA2A, GLIS3 and C2CD4B loci are associated with reduced glucose-stimulated beta cell function in middle-aged Danish people. In: Diabetologia. 2010 ; Vol. 53, No. 8. pp. 1647-55.

Bibtex

@article{16336214f559411290a0c02f9d858e73,
title = "Variants at DGKB/TMEM195, ADRA2A, GLIS3 and C2CD4B loci are associated with reduced glucose-stimulated beta cell function in middle-aged Danish people",
abstract = "A meta-analysis of 21 genome-wide association studies identified 11 novel genetic loci implicated in fasting glucose homeostasis. We aimed to evaluate the impact of these variants on insulin release and insulin sensitivity estimated from OGTTs.",
keywords = "Denmark, Diacylglycerol Kinase, Female, Genetic Loci, Genetic Predisposition to Disease, Genome-Wide Association Study, Genotype, Glucose, Humans, Insulin-Secreting Cells, Male, Middle Aged, Receptors, Adrenergic, alpha-2, Transcription Factors",
author = "Boesgaard, {T W} and N Grarup and Torben J{\o}rgensen and Knut Borch-Johnsen and T Hansen and Oluf Pedersen and {Meta-Analysis of Glucose and Insulin-Related Trait Consortium (MAGIC)}",
year = "2010",
month = aug,
day = "1",
doi = "10.1007/s00125-010-1753-5",
language = "English",
volume = "53",
pages = "1647--55",
journal = "Diabetologia",
issn = "0012-186X",
publisher = "Springer",
number = "8",

}

RIS

TY - JOUR

T1 - Variants at DGKB/TMEM195, ADRA2A, GLIS3 and C2CD4B loci are associated with reduced glucose-stimulated beta cell function in middle-aged Danish people

AU - Boesgaard, T W

AU - Grarup, N

AU - Jørgensen, Torben

AU - Borch-Johnsen, Knut

AU - Hansen, T

AU - Pedersen, Oluf

AU - Meta-Analysis of Glucose and Insulin-Related Trait Consortium (MAGIC)

PY - 2010/8/1

Y1 - 2010/8/1

N2 - A meta-analysis of 21 genome-wide association studies identified 11 novel genetic loci implicated in fasting glucose homeostasis. We aimed to evaluate the impact of these variants on insulin release and insulin sensitivity estimated from OGTTs.

AB - A meta-analysis of 21 genome-wide association studies identified 11 novel genetic loci implicated in fasting glucose homeostasis. We aimed to evaluate the impact of these variants on insulin release and insulin sensitivity estimated from OGTTs.

KW - Denmark

KW - Diacylglycerol Kinase

KW - Female

KW - Genetic Loci

KW - Genetic Predisposition to Disease

KW - Genome-Wide Association Study

KW - Genotype

KW - Glucose

KW - Humans

KW - Insulin-Secreting Cells

KW - Male

KW - Middle Aged

KW - Receptors, Adrenergic, alpha-2

KW - Transcription Factors

U2 - 10.1007/s00125-010-1753-5

DO - 10.1007/s00125-010-1753-5

M3 - Journal article

C2 - 20419449

VL - 53

SP - 1647

EP - 1655

JO - Diabetologia

JF - Diabetologia

SN - 0012-186X

IS - 8

ER -

ID: 33501934