Juul Holst Group

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  1. 2022
  2. Published

    Investigating the roles of hyperglycaemia, hyperinsulinaemia and elevated free fatty acids in cardiac function in patients with type 2 diabetes via treatment with insulin compared with empagliflozin: Protocol for the HyperCarD2 randomised, crossover trial

    Thirumathyam, R., Richter, Erik A., Goetze, Jens P. , Fenger, M., van Hall, Gerrit, Dixen, Ulrik, Holst, Jens Juul, Madsbad, Sten, Vejlstrup, N., Madsen, Per & Jørgensen, N. B., 2022, In: B M J Open. 12, 8, 10 p., e054100.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    LEAP2 reduces postprandial glucose excursions and ad libitum food intake in healthy men

    Hagemann, C. A., Jensen, M. S., Holm, Stephanie Kjærulff, Gasbjerg, Lærke Smidt, Byberg, Sarah, Skov-Jeppesen, Kirsa, Hartmann, Bolette, Holst, Jens Juul, Dela, Flemming, Vilsbøll, Tina, Christensen, Mikkel Bring, Holst, Birgitte & Knop, Filip Krag, 2022, In: Cell Reports Medicine. 3, 4, 100582.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Long-term outcomes of dietary carbohydrate restriction for HbA1c reduction in type 2 diabetes mellitus are needed. Reply to Kang J and Ma E [letter]

    Thomsen, M. N., Astrup, A., Holst, Jens Juul, Madsbad, Sten, Magkos, Faidon, Haugaard, Steen Bendix & Krarup, T., 2022, In: Diabetologia. 65, 6, p. 1060-1062 3 p.

    Research output: Contribution to journal › Comment/debate › Research

  5. Published

    Molecular and in vivo phenotyping of missense variants of the human glucagon receptor

    van der Velden, W. J. C., Lindquist, Peter, Madsen, Jakob Sture, Stassen, R. H. M. J., Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Hauser, Alexander Sebastian & Rosenkilde, M. M., 2022, In: Journal of Biological Chemistry. 298, 2, 101413.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    N-terminal alterations turn the gut hormone GLP-2 into an antagonist with gradual loss of GLP-2 receptor selectivity towards more GLP-1 receptor interaction

    Gabe, M. B. N., Gasbjerg, Lærke Smidt, Gadgaard, S., Lindquist, Peter, Holst, Jens Juul & Rosenkilde, Mette, 2022, In: British Journal of Pharmacology. 179, 18, p. 4473-4485

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Neurotensin secretion after Roux-en-Y gastric bypass, sleeve gastrectomy, and truncal vagotomy with pyloroplasty

    Svane, M. S., Øhrstrøm, C. C., Plamboeck, A., Jørgensen, Nils Bruun, Bojsen-Møller, K. N., Dirksen, C., Martinussen, C., Vilsbøll, Tina, Hartmann, Bolette, Deacon, Carolyn F., Kristiansen, V. B., Knop, Filip Krag, Svendsen, Lars Bo, Madsbad, Sten, Holst, Jens Juul & Veedfald, Simon, 2022, In: Neurogastroenterology and Motility. 34, 1, e14210.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Novel agonist- and antagonist-based radioligands for the GLP-2 receptor - useful tools for studies of basic GLP-2R pharmacology

    Gadgaard, S., van der Velden, W. J. C., Schiellerup, S. P., Dal, Jenna Elizabeth Hunt, Gabe, M. B. N., Windeløv, Johanne Agerlin, Boer, G. A., Kissow, Hannelouise, Ørskov, Cathrine, Holst, Jens Juul, Hartmann, Bolette & Rosenkilde, M. M., 2022, In: British Journal of Pharmacology. 179, 9, p. 1998-2015

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    On measurements of glucagon secretion in healthy, obese, and Roux-en-Y gastric bypass operated individuals using sandwich ELISA

    Albrechtsen, Nicolai Jacob Wewer, Kjeldsen, Sasha Alexandra Sampson, Jensen, N. J., Rungby, Jørgen, Veedfald, Simon, Bojsen-Møller, K. N., Dirksen, C., Jensen, Christian Zinck, Martinussen, C., Madsbad, Sten & Holst, Jens Juul, 2022, In: Scandinavian Journal of Clinical & Laboratory Investigation. 82, 1, p. 75-83

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Opposing effects of chronic glucagon receptor agonism and antagonism on amino acids, hepatic gene expression, and alpha cells

    Elmelund, E., Galsgaard, Katrine Douglas, Johansen, C. D., Trammell, Sam, Billeschou, Anna, Winther-Sørensen, Marie, Dal, Jenna Elizabeth Hunt, Sorensen, Charlotte Mehlin, Kruse, Thomas, Lau, J. F., Grevengoed, Trisha Jean, Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2022, In: iScience. 25, 11, 20 p., 105296.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Opposing roles of the entero-pancreatic hormone urocortin-3 in glucose metabolism in rats

    Grunddal, Kaare Villum, Trammell, Sam, Bæch-Laursen, C., Andersen, Daniel Bjørklund, Xu, S. F. S., Andersen, H., Gillum, M. P., Ghiasi, S. M., Novak, Ivana, Tyrberg, B., Li, C., Rosenkilde, Mette, Hartmann, Bolette, Holst, Jens Juul & Kuhre, Rune Ehrenreich, 2022, In: Diabetologia. 65, p. 1018–1031

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Peptides in the regulation of glucagon secretion

    Andersen, Daniel Bjørklund & Holst, Jens Juul, 2022, In: Peptides. 148, 19 p., 170683.

    Research output: Contribution to journal › Review › Research › peer-review

  13. Published

    Prolonged lipopolysaccharide-induced illness elevates glucagon-like peptide-1 and suppresses peptide YY: A human-randomized cross-over trial

    Brodersen, K., Mose, M., Ramer Mikkelsen, U., Jørgensen, J. O. L., Festersen Nielsen, M., Møller, N., Wegeberg, A., Brock, C., Hartmann, Bolette, Holst, Jens Juul & Rittig, N., 2022, In: Physiological Reports. 10, 18, 12 p., e15462.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Reply - Letter to the editor - On carbohydrate restriction and health-related quality of life and cognition in type 2 diabetes

    Jensen, N. J., Thomsen, M. N., Skytte, M. J., Astrup, A., Holst, Jens Juul, Madsbad, Sten, Magkos, Faidon, Miskowiak, Kamilla, Haugaard, Steen Bendix, Krarup, T. & Rungby, Jørgen, 2022, In: Clinical Nutrition. 41, 9, p. 2061-2062 2 p.

    Research output: Contribution to journal › Comment/debate › Research

  15. Published

    Role of endogenous incretins in the regulation of postprandial lipoprotein metabolism

    Taskinen, M., Matikainen, N., Björnson, E., Söderlund, S., Ainola, M., Hakkarainen, A., Lundbom, N., Sihlbom, C., Thorsell, A., Andersson, L., Adiels, M., Hartmann, Bolette, Deacon, Carolyn F., Holst, Jens Juul, Packard, C. J. & Borén, J., 2022, In: European Journal of Endocrinology. 187, 1, p. 75-84 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Segmental reversal of the distal small intestine in a short bowel syndrome model in piglets showed detrimental effect on weight gain

    Schmidt, L. H., Aa, J. S., Hartmann, Bolette, Madsen, G. I., Qvist, N. & Ellebæk, M. B., 2022, In: BMC Gastroenterology. 22, 1, 9 p., 349.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Studies in Rats of Combined Muscle and Liver Perfusion and of Muscle Extract Indicate That Contractions Release a Muscle Hormone Directly Enhancing Hepatic Glycogenolysis

    Han, X. X., Holst, Jens Juul & Galbo, Henrik, 2022, In: Journal of Personalized Medicine. 12, 5, 12 p., 837.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    THERAPY OF ENDOCRINE DISEASE: Amylin and calcitonin - physiology and pharmacology

    Mathiesen, D. S., Lund, A., Holst, Jens Juul, Knop, Filip Krag, Lutz, T. A. & Bagger, J. I., 2022, In: European Journal of Endocrinology. 186, 6, p. R93-R111

    Research output: Contribution to journal › Review › Research › peer-review

  19. Published

    The Glucagon Receptor Antagonist LY2409021 has No Effect on Postprandial Glucose in Type 2 Diabetes

    Hædersdal, S., Lund, A., Maagensen, H., Nielsen-Hannerup, E., Gasbjerg, Lærke Smidt, Rosenkilde, Mette, Forman, Julie Lyng, van Hall, Gerrit, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 2022, In: European Journal of Endocrinology. 186, 2, p. 207-221 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    The Liver-Alpha Cell Axis in Health and in Disease

    Richter, Michael Martin, Galsgaard, Katrine Douglas, Elmelund, E., Knop, Filip Krag, Suppli, M. P., Holst, Jens Juul, Winther-Sørensen, Marie, Kjeldsen, Sasha Alexandra Sampson & Albrechtsen, Nicolai Jacob Wewer, 2022, In: Diabetes. 71, +, p. 1852–1861

    Research output: Contribution to journal › Review › Research › peer-review

  21. Published

    The Location of Missense Variants in the Human GIP Gene Is Indicative for Natural Selection

    Lindquist, Peter, Gasbjerg, Lærke Smidt, Mokrosinski, J., Holst, Jens Juul, Hauser, Alexander Sebastian & Rosenkilde, Mette, 2022, In: Frontiers in Endocrinology. 13, 14 p., 891586.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    The Role of D-allulose and Erythritol on the Activity of the Gut Sweet Taste Receptor and Gastrointestinal Satiation Hormone Release in Humans: A Randomized, Controlled Trial

    Teysseire, F., Bordier, V., Budzinska, A., Weltens, N., Rehfeld, Jens Frederik, Holst, Jens Juul, Hartmann, Bolette, Beglinger, C., Van Oudenhove, L., Wölnerhanssen, B. K. & Meyer-Gerspach, A. C., 2022, In: Journal of Nutrition. 152, 5, p. 1228–1238,

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    The Sensory Mechanisms of Nutrient-Induced GLP-1 Secretion

    Hjørne, A. P., Modvig, Ida Marie & Holst, Jens Juul, 2022, In: Metabolites. 12, 5, 15 p., 420.

    Research output: Contribution to journal › Review › Research › peer-review

  24. Published

    The effect of curcumin on hepatic fat content in individuals with obesity

    Hellmann, P. H., Bagger, J. I., Carlander, K. R., Forman, Julie Lyng, Chabanova, E., Svenningsen, J. S., Holst, Jens Juul, Gillum, M. P., Vilsbøll, Tina & Knop, Filip Krag, 2022, In: Diabetes, Obesity and Metabolism. 24, 11, p. 2192-2202 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    The glucagon receptor antagonist LY2409021 does not affect gastrointestinal-mediated glucose disposal or the incretin effect in individuals with and without type 2 diabetes

    Hædersdal, S., Lund, A., Nielsen-Hannerup, E., Maagensen, H., Forman, Julie Lyng, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 2022, In: European Journal of Endocrinology. 187, 4, p. 507-518 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    The incretin/glucagon system as a target for pharmacotherapy of obesity

    Del Prato, S., Gallwitz, B., Holst, Jens Juul & Meier, J. J., 2022, In: Obesity Reviews. 23, 2, 13 p., e13372.

    Research output: Contribution to journal › Journal article › Research › peer-review

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