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Efficacy and safety of meal-time administration of short-acting exenatide for glycaemic control in type 1 diabetes (MAG1C): a randomised, double-blind, placebo-controlled trial
Johansen, N. J., Dejgaard, T. F., Lund, A., Schluntz, C., Frandsen, C. S., Forman, Julie Lyng, Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Pedersen-Bjergaard, Ulrik, Madsbad, Sten, Vilsbøll, Tina, Andersen, H. U. & Knop, Filip Krag, 2020, In: The Lancet Diabetes & Endocrinology. 8, 4, p. 313-324 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of short-acting exenatide added three times daily to insulin therapy on bone metabolism in type 1 diabetes
Johansen, N. J., Dejgaard, T. F., Lund, A., Schlüntz, Camilla, Hartmann, Bolette, Holst, Jens Juul, Vilsbøll, Tina, Andersen, H. U. & Knop, Filip Krag, 2022, In: Diabetes, Obesity and Metabolism. 24, 2, p. 221-227Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of an intensive lifestyle intervention on the underlying mechanisms of improved glycaemic control in individuals with type 2 diabetes: a secondary analysis of a randomised clinical trial
Johansen, M. Y., Karstoft, K., MacDonald, C. S., Hansen, K. B., Ellingsgaard, H., Hartmann, Bolette, Albrechtsen, Nicolai Jacob Wewer, Vaag, A. A., Holst, Jens Juul, Pedersen, Bente Klarlund & Ried-Larsen, M., 2020, In: Diabetologia. 63, p. 2410-2422 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Ghrelin Does Not Directly Stimulate Secretion of Glucagon-like Peptide-1
Jepsen, Sara Lind, Vestergaard, E. T., Larraufie, P., Gribble, F. M., Reimann, F., Jorgensen, J. O. L., Holst, Jens Juul & Kuhre, Rune Ehrenreich, 2020, In: Journal of Clinical Endocrinology & Metabolism. 105, 1, p. 266-275Research output: Contribution to journal › Journal article › Research › peer-review
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Paracrine Crosstalk between Intestinal L- and D-cells Controls Secretion of Glucagon-Like Peptide-1 in mice
Jepsen, Sara Lind, Grunddal, Kaare Villum, Albrechtsen, Nicolai Jacob Wewer, Engelstoft, M. S., Gabe, M. B. N., Jensen, E. P., Ørskov, Cathrine, Poulsen, Steen Seier, Rosenkilde, M. M., Pedersen, J., Gribble, F. M., Reimann, F., Deacon, Carolyn F., Schwartz, Thue W., Christ, A. D., Martin, R. E. & Holst, Jens Juul, 2019, In: American Journal of Physiology: Endocrinology and Metabolism. 317, 6, p. E1081-E1093Research output: Contribution to journal › Journal article › Research › peer-review
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Antagonizing somatostatin receptor subtype 2 and 5 reduces blood glucose in a gut- and GLP-1R-dependent manner
Jepsen, Sara Lind, Albrechtsen, Nicolai Jacob Wewer, Windeløv, Johanne Agerlin, Galsgaard, Katrine Douglas, Dal, Jenna Elizabeth Hunt, Farb, T. B., Kissow, Hannelouise, Pedersen, J., Deacon, Carolyn F., Martin, R. E. & Holst, Jens Juul, 2021, In: JCI insight. 6, 4, 15 p., e143228.Research output: Contribution to journal › Journal article › Research › peer-review
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Glucagon-like peptide 2 improves nutrient absorption and nutritional status in short-bowel patients with no colon
Jeppesen, Palle Bekker, Hartmann, Bolette, Thulesen, J., Graff, J., Lohmann, J., Hansen, B. S., Tofteng, F., Poulsen, Steen Seier, Madsen, J. L., Holst, Jens Juul & Mortensen, P. B., Mar 2001, In: Gastroenterology. 120, 4, p. 806-815 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Elevated plasma glucagon-like peptide 1 and 2 concentrations in ileum resected short bowel patients with a preserved colon
Jeppesen, Palle Bekker, Hartmann, Bolette, Thulesen, J., Hansen, B. S., Holst, Jens Juul, Poulsen, Steen Seier & Mortensen, P. B., Sep 2000, In: Gut. 47, 3, p. 370-6 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Exploratory analysis of eating- and physical activity-related outcomes from a randomized controlled trial for weight loss maintenance with exercise and liraglutide single or combination treatment
Jensen, Simon Birk Kjær, Janus, C., Lundgren, J. R., Juhl, C. R., Sandsdal, Rasmus Michael, Olsen, L. M., Andresen, A., Borg, S. A., Jacobsen, I. C., Finlayson, G., Stallknecht, Bente Merete, Holst, Jens Juul, Madsbad, Sten & Torekov, Signe Sørensen, 2022, In: Nature Communications. 13, 1, 11 p., 4770.Research output: Contribution to journal › Journal article › Research › peer-review
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Protocol for a randomised controlled trial of the combined effects of the GLP-1 receptor agonist liraglutide and exercise on maintenance of weight loss and health after a very low-calorie diet
Jensen, Simon Birk Kjær, Lundgren, J. R., Janus, C., Juhl, C. R., Olsen, L. M., Rosenkilde, M., Holst, Jens Juul, Stallknecht, Bente Merete, Madsbad, Sten & Torekov, Signe Sørensen, 2019, In: BMJ Open. 9, 11, 10 p., e031431.Research output: Contribution to journal › Journal article › Research › peer-review
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Weight loss maintenance with exercise and liraglutide improves glucose tolerance, glucagon response, and beta cell function
Jensen, Simon Birk Kjær, Juhl, C. R., Janus, C., Lundgren, J. R., Martinussen, C., Wiingaard, C., Knudsen, C., Frikke-Schmidt, Ruth, Stallknecht, Bente Merete, Holst, Jens Juul, Madsbad, Sten & Torekov, Signe Sørensen, 2023, In: Obesity. 31, 4, p. 977-989 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Reply - Letter to the editor - On carbohydrate restriction and health-related quality of life and cognition in type 2 diabetes
Jensen, N. J., Thomsen, M. N., Skytte, M. J., Astrup, A., Holst, Jens Juul, Madsbad, Sten, Magkos, Faidon, Miskowiak, Kamilla, Haugaard, Steen Bendix, Krarup, T. & Rungby, Jørgen, 2022, In: Clinical Nutrition. 41, 9, p. 2061-2062 2 p.Research output: Contribution to journal › Comment/debate › Research
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Weight-loss induced by carbohydrate restriction does not negatively affect health-related quality of life and cognition in people with type 2 diabetes: A randomised controlled trial
Jensen, N. J., Wodschow, H. Z., Skytte, M. J., Samkani, A., Astrup, A., Frystyk, J., Hartmann, Bolette, Holst, Jens Juul, Larsen, T. M., Madsbad, Sten, Magkos, Faidon, Miskowiak, Kamilla, Haugaard, Steen Bendix, Krarup, T., Rungby, Jørgen & Thomsen, M. N., 2022, In: Clinical Nutrition. 41, 7, p. 1605-1612 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The effect of dietary carbohydrate restriction beyond weight loss on health-related quality of life and cognition
Jensen, N. J., Wodschow, H. Z., fbg982, fbg982, Samkani, A., Astrup, A., Frystyk, J., Hartmann, Bolette, Holst, Jens Juul, Larsen, T. M., Madsbad, Sten, Magkos, Faidon, Miskowiak, Kamilla, Rungby, Jørgen, Haugaard, Steen Bendix & Thomsen, M. N., 2021, In: Diabetologia. 64, SUPPL 1, p. 62-63 114.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Glucagon-like peptide-1 receptor regulation of basal dopamine transporter activity is species-dependent
Jensen, M. E., Galli, A., Thomsen, M., Jensen, Kathrine Louise, Thomsen, G. K., Klausen, M. K., Vilsbøll, Tina, Christensen, Mikkel Bring, Holst, Jens Juul, Owens, A., Robertson, S., Daws, L., Zanella, D., Gether, Ulrik, Knudsen, Gitte Moos & Fink-Jensen, Anders, 2020, In: Neurochemistry International. 138, 9 p., 104772.Research output: Contribution to journal › Journal article › Research › peer-review
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GLP-1-induced renal vasodilation in rodents depends exclusively on the known GLP-1 receptor and is lost in pre-hypertensive rats
Jensen, E. P., Møller, S., Hviid, A. V. R., Veedfald, Simon, Holst, Jens Juul, Pedersen, Jens, Ørskov, Cathrine & Sorensen, Charlotte Mehlin, 2020, In: American Journal of Physiology: Renal Physiology. 318, 6, p. F1409-F1417Research output: Contribution to journal › Journal article › Research › peer-review
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Responses of gut and pancreatic hormones, bile acids, and fibroblast growth factor-21 differ to glucose, protein, and fat ingestion after gastric bypass surgery
Jensen, C. Z., Bojsen-Møller, K. N., Svane, M. S., Holst, L. M., Hermansen, K., Hartmann, Bolette, Albrechtsen, Nicolai Jacob Wewer, Kuhre, Rune Ehrenreich, Kristiansen, V. B., Rehfeld, Jens Frederik, Clausen, T. R., Holst, Jens Juul & Madsbad, Sten, 2020, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 318, 4, p. G661-G672 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Gastric Bypass with Different Biliopancreatic Limb Lengths Results in Similar Post-absorptive Metabolomics Profiles
Jarak, I., Pereira, S. S., Carvalho, R. A., Oliveira, P. F., Alves, M. G., Guimarães, M., Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Nora, M. & Monteiro, M. P., 2020, In: Obesity Surgery. 30, 3, p. 1068-1078 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Habitual activity associates with lower fasting and greater glucose-induced GLP-1 response in men
Janus, C., Vistisen, D., Amadid, H., Witte, D. R., Lauritzen, T., Brage, S., Bjerregaard, A., Hansen, Torben, Holst, Jens Juul, Jørgensen, M. E., Pedersen, Oluf Borbye, Færch, K. & Torekov, Signe Sørensen, 2019, In: Endocrine Connections. 8, 12, p. 1607–1617 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Glucagon Receptor Signaling and Glucagon Resistance
Janah, L., Kjeldsen, Sasha Alexandra Sampson, Galsgaard, Katrine Douglas, Winther-Sørensen, Marie, Stojanovska, E., Pedersen, Jens, Knop, Filip Krag, Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2019, In: International Journal of Molecular Sciences. 20, 13, 27 p., 3314.Research output: Contribution to journal › Review › Research › peer-review
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Effects of aerobic training and semaglutide treatment on pancreatic β-cell secretory function in patients with type 2 diabetes
Ingersen, Arthur, Schmücker, Malte, Alexandersen, C., Graungaard, B., Thorngreen, T., Borch, Jacob, Holst, Jens Juul, Helge, Jørn Wulff & Dela, Flemming, 2023, In: Journal of Clinical Endocrinology and Metabolism. 108, 11, p. 2798–2811Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Adults with pathogenic MC4R mutations have increased final height and thereby increased bone mass
Iepsen, E. W., Zhang, J., Hollensted, M., Madsbad, Sten, Hansen, Torben, Holst, Jens Juul, Jørgensen, Niklas Rye, Holm, Jens-Christian & Torekov, Signe Sørensen, 2020, In: Journal of Bone and Mineral Metabolism. 38, 1, p. 117-125 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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GLP-1 Receptor Agonist Treatment in Morbid Obesity and Type 2 Diabetes Due to Pathogenic Homozygous Melanocortin-4 Receptor Mutation: A Case Report
Iepsen, E. W., Have, C. T., Veedfald, Simon, Madsbad, Sten, Holst, Jens Juul, Grarup, Niels, Pedersen, Oluf Borbye, Brandslund, I., Holm, Jens-Christian, Hansen, Torben & Torekov, Signe Sørensen, 2020, In: Cell Reports Medicine. 1, 1, 8 p., 100006.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP-1 receptor agonist treatment increases bone formation and prevents bone loss in weight-reduced obese women
Iepsen, E. P. W., Lundgren, J. R., Hartmann, Bolette, Pedersen, Oluf Borbye, Hansen, Torben, Jørgensen, Niklas Rye, Jensen, J. B., Holst, Jens Juul, Madsbad, Sten & Torekov, Signe Sørensen, 2015, In: The Journal of clinical endocrinology and metabolism. 100, 8, p. 2909 –2917 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The glucagon receptor antagonist LY2409021 does not affect gastrointestinal-mediated glucose disposal or the incretin effect in individuals with and without type 2 diabetes
Hædersdal, S., Lund, A., Nielsen-Hannerup, E., Maagensen, H., Forman, Julie Lyng, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 2022, In: European Journal of Endocrinology. 187, 4, p. 507-518 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The Glucagon Receptor Antagonist LY2409021 has No Effect on Postprandial Glucose in Type 2 Diabetes
Hædersdal, S., Lund, A., Maagensen, H., Nielsen-Hannerup, E., Gasbjerg, Lærke Smidt, Rosenkilde, Mette, Forman, Julie Lyng, van Hall, Gerrit, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 2022, In: European Journal of Endocrinology. 186, 2, p. 207-221 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The role of glucagon in the acute therapeutic effects of SGLT2 inhibition
Hædersdal, S., Lund, A., Nielsen-Hannerup, E., Maagensen, H., van Hall, Gerrit, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 2020, In: Diabetes. 69, 12, p. 2619-2629 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Endogenous glucagon-like peptide- 1 and 2 are essential for regeneration after acute intestinal injury in mice
Hytting-Andreasen, R., Balk-Møller, E., Hartmann, Bolette, Pedersen, Jens, Windeløv, Johanne Agerlin, Holst, Jens Juul & Kissow, Hannelouise, 2018, In: PLoS ONE. 13, 6, p. 1-14 e0198046.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Patients with Long QT Syndrome Due to Impaired hERG-encoded Kv11.1 Potassium Channel Have Exaggerated Endocrine Pancreatic and Incretin Function Associated with Reactive Hypoglycemia
Hyltén-Cavallius, L., Iepsen, E. W., Albrechtsen, Nicolai Jacob Wewer, Svendstrup, M., Lubberding, Anniek Frederike, Hartmann, Bolette, Jespersen, Thomas, Linneberg, Allan René, Christiansen, M., drb459, drb459, Pedersen, Oluf Borbye, Holst, Jens Juul, Kanters, Jørgen K., Hansen, Torben & Torekov, Signe Sørensen, 2017, In: Circulation. 135, 18, p. 1705-1719 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The diurnal variation of bone formation is attenuated in adult patients with type 2 diabetes
Hygum, K., Starup-Linde, J., Harslor, T., Jørgensen, Niklas Rye, Hartmann, Bolette, Holst, Jens Juul & Langdahl, B. L., 2019, In: European Journal of Endocrinology. 181, 3, p. 221-231Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of liraglutide treatment on jejunostomy output in patients with short bowel syndrome: An open-label pilot study
Hvistendahl, M., Brandt, C. F., Tribler, S., Naimi, R. M., Hartmann, Bolette, Holst, Jens Juul, Rehfeld, Jens Frederik, Hornum, Mads, Andersen, Jens Rikardt, Henriksen, B. M., Brøbech Mortensen, P. & Jeppesen, Palle Bekker, 2018, In: Journal of Parenteral and Enteral Nutrition. 42, 1, p. 112-121 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pharmacological activation of TGR5 promotes intestinal growth via a GLP-2 dependent pathway in mice
Dal, Jenna Elizabeth Hunt, Billeschou, Anna, Windeløv, Johanne Agerlin, Hartmann, Bolette, Ullmer, C., Holst, Jens Juul & Kissow, Hannelouise, 2020, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 318, 6, p. G980-G987Research output: Contribution to journal › Journal article › Research › peer-review
- Published
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Dietary Fiber Is Essential to Maintain Intestinal Size, L-Cell Secretion, and Intestinal Integrity in Mice
Dal, Jenna Elizabeth Hunt, Hartmann, Bolette, Schoonjans, K., Holst, Jens Juul & Kissow, Hannelouise, 2021, In: Frontiers in Endocrinology. 12, 10 p., 640602.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Intestinal Growth in Glucagon Receptor Knockout Mice Is Not Associated With the Formation of AOM/DSS-Induced Tumors
Dal, Jenna Elizabeth Hunt, Yassin, M., Olsen, Jørgen, Hartmann, Bolette, Holst, Jens Juul & Kissow, Hannelouise, 2021, In: Frontiers in Endocrinology. 12, 7 p., 695145.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucose- and Bile Acid-Stimulated Secretion of Gut Hormones in the Isolated Perfused Intestine Is Not Impaired in Diet-Induced Obese Mice
Dal, Jenna Elizabeth Hunt, Holst, Jens Juul & Jepsen, Sara Lind, 2022, In: Frontiers in Endocrinology. 13, 10 p., 884501.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dietary impact on fasting and stimulated GLP-1 secretion in different metabolic conditions - a narrative review
Huber, H., Schieren, A., Holst, Jens Juul & Simon, M., 2024, In: The American Journal of Clinical Nutrition. 119, 3, p. 599-627Research output: Contribution to journal › Review › Research › peer-review
- Published
What combines best with GLP-1 for obesity treatment: GIP receptor agonists or antagonists?
Holst, Jens Juul, 2021, In: Cell Reports Medicine. 2, 5, 2 p., 100284.Research output: Contribution to journal › Comment/debate › Research
- Published
The role of incretins on insulin function and glucose homeostasis
Holst, Jens Juul, Gasbjerg, Lærke Smidt & Rosenkilde, Mette, 2021, In: Endocrinology. 162, 7, 10 p., bqab065.Research output: Contribution to journal › Review › Research › peer-review
- Published
Incretin therapy for diabetes mellitus type 2
Holst, Jens Juul, 2020, In: Current Opinion in Endocrinology, Diabetes and Obesity. 27, 1, p. 2-10Research output: Contribution to journal › Review › Research › peer-review
- Published
Long-acting glucagon-like peptide-1 receptor agonist-status December 2018
Holst, Jens Juul, 2019, In: Annals of Translational Medicine. 7, 5, 6 p., 83 .Research output: Contribution to journal › Editorial › Research
- Published
Incretin-based therapy of metabolic disease
Holst, Jens Juul, 2023, In: Danish Medical Journal. 70, 1, A10220597.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-1 (GLP-1): are its roles as endogenous hormone and therapeutic wizard congruent?
Holst, Jens Juul, 2022, In: Journal of Internal Medicine. 291, 5, p. 557-573Research output: Contribution to journal › Review › Research › peer-review
- Published
Treatment of Type 2 Diabetes and Obesity on the Basis of the Incretin System: The 2021 Banting Medal for Scientific Achievement Award Lecture
Holst, Jens Juul, 2021, In: Diabetes. 70, 11, p. 2468-2475 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon and other proglucagon-derived peptides in the pathogenesis of obesity
Holst, Jens Juul, 2022, In: Frontiers in Nutrition. 9, 8 p., 964406.Research output: Contribution to journal › Review › Research › peer-review
- Published
Discovery of the GI Effects of GLP-1: An Historical Perspective
Holst, Jens Juul, 2022, In: Digestive Diseases and Sciences. 67, p. 2716-2720Research output: Contribution to journal › Review › Research › peer-review
- Published
Bone resorption is decreased postprandially by intestinal factors and glucagon-like peptide-2 is a possible candidate
Holst, Jens Juul, Hartmann, Bolette, Gottschalck, I. B., Jeppesen, Palle Bekker, Miholic, J. & Henriksen, D. B., Jul 2007, In: Scandinavian Journal of Gastroenterology. 42, 7, p. 814-20 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Recent advances of GIP and future horizons
Holst, Jens Juul & Rosenkilde, Mette, 2020, In: Peptides. 125, 6 p., 170230.Research output: Contribution to journal › Review › Research › peer-review
- Published
Which to choose, an oral or an injectable glucagon-like peptide-1 receptor agonist?
Holst, Jens Juul, 2019, In: The Lancet. 394, 10192, p. 4-6Research output: Contribution to journal › Editorial › Research › peer-review
- Published
GLP-1 - Incretin and pleiotropic hormone with pharmacotherapy potential. Increasing secretion of endogenous GLP-1 for diabetes and obesity therapy
Holst, Jens Juul, Jepsen, Sara Lind & Modvig, Ida Marie, 2022, In: Current Opinion in Pharmacology. 63, p. 1-7 102189.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GIP as a Therapeutic Target in Diabetes and Obesity: Insight From Incretin Co-agonists
Holst, Jens Juul & Rosenkilde, M. M., 2020, In: Journal of Clinical Endocrinology & Metabolism. 105, 8, p. E2710-E2716 7 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Glucagon 100 years. Important, but still enigmatic
Holst, Jens Juul, 2023, In: Peptides. 161, 6 p., 170942.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Searching for the physiological role of glucose-dependent insulinotropic polypeptide
Holst, Jens Juul, Windeløv, Johanne Agerlin, Boer, G. A., Pedersen, Jens, Svendsen, B., Christensen, M., Torekov, Signe Sørensen, Asmar, M., Hartmann, Bolette & Nissen, A., 1 Apr 2016, In: Journal of Diabetes Investigation. 7, S1, p. 8-12 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
From the Incretin Concept and the Discovery of GLP-1 to Today's Diabetes Therapy
Holst, Jens Juul, 2019, In: Frontiers in Endocrinology. 10, 10 p., 260.Research output: Contribution to journal › Review › Research › peer-review
- Published
The incretin system in healthy humans: The role of GIP and GLP-1
Holst, Jens Juul, 2019, In: Metabolism. 96, p. 46-55Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Actions of glucagon-like peptide-1 receptor ligands in the gut
Holst, Jens Juul, Andersen, Daniel Bjørklund & Grunddal, Kaare Villum, 2022, In: British Journal of Pharmacology. 179, 4, p. 727-742Research output: Contribution to journal › Review › Research › peer-review
- Published
New Lessons from the gut: Studies of the role of gut peptides in weight loss and diabetes resolution after gastric bypass and sleeve gastrectomy
Holst, Jens Juul, Madsbad, Sten, Bojsen-Møller, Kirstine Nyvold, Dirksen, C. & Svane, M., 2024, In: Peptides. 176, 9 p., 171199.Research output: Contribution to journal › Review › Research › peer-review
- Published
Glucagon-like peptides 1 and 2, enteroglucagon, glicentin and oxyntomodulin
Holst, Jens Juul, Deacon, Carolyn F., Hartmann, Bolette & Pedersen, Jens, 2013, Handbook of Biologically Active Peptides . Kastin, AJ. (ed.). 2 ed. Elsevier, p. 1241-1250 10 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Education
- Published
Physiology of the Incretin Hormones, GIP and GLP-1-Regulation of Release and Posttranslational Modifications
Holst, Jens Juul, Albrechtsen, Nicolai Jacob Wewer, Rosenkilde, Mette & Deacon, Carolyn F., 2019, In: Comprehensive Physiology. 9, 4, p. 1339-1381Research output: Contribution to journal › Journal article › Research › peer-review
- Published
What is Diabetes Remission?
Holst, Jens Juul & Madsbad, Sten, 2021, In: Diabetes Therapy. 12, p. 641-646 6 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Methods and Guidelines for Measurement of Glucagon in Plasma
Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2019, In: International Journal of Molecular Sciences (Online). 20, 10 p., 5416.Research output: Contribution to journal › Review › Research › peer-review
- Published
Secretion and Impact of Gut Hormones in Obesity and Diabetes
Holst, Jens Juul, 2023, Encyclopedia of Cell Biology: Systems, Translational and Specialized Cell Aspects of Cell Biology. Bradshaw, R. A., Hart, G. W. & Stahl, P. D. (eds.). 2 ed. Elsevier, Vol. 6. p. 543-550 8 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Proglucagon processing in porcine and human pancreas
Holst, Jens Juul, Bersani, M., Johnsen, A. H., Kofod, H., Hartmann, Bolette & Ørskov, Cathrine, 1994, In: Journal of Biological Chemistry. 269, 29, p. 18827-33 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GIP infusion in patients with type 1 diabetes seems to attenuate post-prandial glucose excursions after prandial insulin over-dose and physical activity
Hoe, B., Heimburger, S. M. N., Gasbjerg, L. S., Lanng, A. R., Lynggaard, M. B., Hartmann, Bolette, Holst, Jens Juul, Vilsbøll, Tina, Lund, A., Engberg, S., Dejgaard, T. F., Christensen, Mikkel Bring & Knop, Filip Krag, 2020, In: Diabetologia. 63, Suppl. 1, p. S117 1 p., 232.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
The Sensory Mechanisms of Nutrient-Induced GLP-1 Secretion
Hjørne, A. P., Modvig, Ida Marie & Holst, Jens Juul, 2022, In: Metabolites. 12, 5, 15 p., 420.Research output: Contribution to journal › Review › Research › peer-review
- Published
Effect of 6 weeks of very low-volume high-intensity interval training on oral glucose-stimulated incretin hormone response
Hindsø, M., Kuhlman, A. B., Dohlmann, T. L., Lund, M. T., Hartmann, Bolette, Holst, Jens Juul, Larsen, Steen & Helge, Jørn Wulff, 2022, In: European Journal of Sport Science. 22, 3, p. 381-389Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The importance of endogenously secreted GLP-1 and GIP for postprandial glucose tolerance and β-cell function after Roux-en-Y gastric bypass and sleeve gastrectomy surgery
Hindsø, M., Hedbäck, N., Svane, M. S., Møller, A., Martinussen, C., Jørgensen, N. B., Dirksen, C., Gasbjerg, Lærke Smidt, Kristiansen, V. B., Hartmann, Bolette, Rosenkilde, Mette, Holst, Jens Juul, Madsbad, Sten & Bojsen-Møller, K. N., 2023, In: Diabetes. 72, 3, p. 336–347Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The role of GLP-1 in postprandial glucose metabolism after bariatric surgery: a narrative review of human GLP-1 receptor antagonist studies
Hindsø, M., Svane, M. S., Hedbäck, N., Holst, Jens Juul, Madsbad, Sten & Bojsen-Møller, K. N., 2021, In: Surgery for Obesity and Related Diseases. 17, 7, p. 1383-1391Research output: Contribution to journal › Review › Research › peer-review
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Early effects of Roux-en-Y gastric bypass on dietary fatty acid absorption and metabolism in people with obesity and normal glucose tolerance
Hindsø, M., Bojsen-Møller, K. N., Kristiansen, V. B., Holst, Jens Juul, van Hall, Gerrit & Madsbad, Sten, 2022, In: International Journal of Obesity. 46, 7, p. 1359-1365Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Postprandial Dyslipidemia, Hyperinsulinemia, and Impaired Gut Peptides/Bile Acids in Adolescents with Obesity
Higgins, V., Asgari, S., Hamilton, J. K., Wolska, A., Remaley, A. T., Hartmann, Bolette, Holst, Jens Juul & Adeli, K., 2020, In: Journal of Clinical Endocrinology & Metabolism. 105, 4, p. 1228-1241Research output: Contribution to journal › Journal article › Research › peer-review
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Disassociation of bone resorption and formation by GLP-2: a 14-day study in healthy postmenopausal women
Henriksen, D. B., Alexandersen, P., Hartmann, Bolette, Adrian, C. L., Byrjalsen, I., Bone, H. G., Holst, Jens Juul & Christiansen, C., Mar 2007, In: Bone. 40, 3, p. 723-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Four-month treatment with GLP-2 significantly increases hip BMD: a randomized, placebo-controlled, dose-ranging study in postmenopausal women with low BMD
Henriksen, D. B., Alexandersen, P., Hartmann, Bolette, Adrian, C. L., Byrjalsen, I., Bone, H. G., Holst, Jens Juul & Christiansen, C., 2009, In: Bone. 45, 5, p. 833-42 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The role of endogenous GIP and GLP-1 in postprandial bone homeostasis
Helsted, M. M., Gasbjerg, Lærke Smidt, Lanng, A. R., Bergmann, N. C., Stensen, S., Hartmann, Bolette, Christensen, Mikkel Bring, Holst, Jens Juul, Vilsbøll, Tina, Rosenkilde, Mette & Knop, Filip Krag, 2020, In: Bone. 140, 7 p., 115553.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The role of the incretins in the postprandial bone remodelling
Helsted, M. M., Gasbjerg, Lærke Smidt, Lanng, A. R., Stensen, S., Hartmann, Bolette, Christensen, Mikkel Bring, Holst, Jens Juul, Vilsbøll, Tina, Rosenkilde, M. M. & Knop, Filip Krag, 2018, In: Diabetologia. 61, S1, p. S221-S221 449.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
No effect of the turmeric root phenol curcumin on prednisolone-induced gluco-metabolic perturbations in men with overweight or obesity
Hellmann, P. H., Bagger, J. I., Carlander, K. R., Hansen, K. B., Forman, Julie Lyng, Størling, Joachim, Chabanova, E., Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2023, In: Endocrine Connections. 12, 4, e220334.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of curcumin on hepatic fat content in individuals with obesity
Hellmann, P. H., Bagger, J. I., Carlander, K. R., Forman, Julie Lyng, Chabanova, E., Svenningsen, J. S., Holst, Jens Juul, Gillum, M. P., Vilsbøll, Tina & Knop, Filip Krag, 2022, In: Diabetes, Obesity and Metabolism. 24, 11, p. 2192-2202 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GIP affects hepatic fat and brown adipose tissue thermogenesis, but not white adipose tissue transcriptome in T1D
Heimbürger, S. M. N., Hoe, B., Nielsen, C. N., Bergman, N. C., Skov-Jeppesen, Kirsa, Hartmann, Bolette, Holst, Jens Juul, Dela, Flemming, Overgaard, J., Størling, Joachim, Vilsbøll, Tina, Dejgaard, T. F., Havelund, J. F., Gorshkov, V., Kjeldsen, F., Færgeman, N. J. K., Madsen, M. R., Christensen, Mikkel Bring & Knop, Filip Krag, 2022, In: Journal of Clinical Endocrinology and Metabolism. 107, 12, p. 3261–3274Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of 6-day subcutaneous glucose-dependent insulinotropic polypeptide infusion on time in glycaemic range in patients with type 1 diabetes: a randomised, double-blind, placebo-controlled crossover trial
Heimbürger, S. M. N., Hoe, B., Nielsen, C. N., Bergmann, N. C., Hartmann, Bolette, Holst, Jens Juul, Vilsbøll, Tina, Dejgaard, T. F., Christensen, Mikkel Bring & Knop, Filip Krag, 2021, In: Diabetologia. 64, p. 2425-2431Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucose-dependent insulinotropic polypeptide (GIP) induces lipolysis during stable basal insulin substitution and hyperglycemia in men with type 1 diabetes: a randomized, double-blind, placebo-controlled, crossover clinical trial
Heimburger, S. M., Nielsen, C. N., Calanna, S., Holst, Jens Juul, Vilsbøll, Tina, Knop, Filip Krag & Christensen, Mikkel Bring, 2022, In: Diabetes, Obesity and Metabolism. 24, 1, p. 142-147Research output: Contribution to journal › Journal article › Research › peer-review
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Six-day sc GIP infusion increases plasma NEFA without altering the adipose tissue transcriptome, GIPR levels or plasma markers of inflammation in patients with type 1 diabetes
Heimburger, S. M. N., Hoe, B., Nielsen, C. N., Hartmann, Bolette, Holst, Jens Juul, Dela, Flemming, Overgaard, J., Størling, Joachim, Vilsbøll, Tina, Dejgaard, T. F., Pyke, C., Christensen, M. B. & Knop, Filip Krag, 2021, In: Diabetologia. 64, SUPPL 1, p. 258-258 494.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Six-day subcutaneous GIP infusion increases glycaemic time in range in patients with type 1 diabetes
Heimbuerger, S. M. N., Hoe, B., Nielsen, C. N., Bergmann, N. C., Hartmann, Bolette, Holst, Jens Juul, Størling, Joachim, Vilsbøll, Tina, Dejgaard, T. F., Christensen, Mikkel Bring & Knop, Filip Krag, 2020, In: Diabetologia. 63, SUPPL 1, p. S73 1 p., 145.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Effect of Meal Texture on Postprandial Glucose Excursions and Gut Hormones After Roux-en-Y Gastric Bypass and Sleeve Gastrectomy
Hedbäck, N., Hindsø, M., Bojsen-Møller, K. N., Linddal, A. K., Jørgensen, N. B., Dirksen, C., Møller, A., Kristiansen, V. B., Hartmann, Bolette, Holst, Jens Juul, Svane, M. S. & Madsbad, Sten, 2022, In: Frontiers in Nutrition. 9, 889710.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of meal texture on glucose excursions after bariatric surgery
Hedbäck, N., Hindso, M., Linddal, A. K., Bojsen-Moller, K. N., Jorgensen, N. B., Dirksen, C., Moller, A., Kristiansen, V. B., Holst, Jens Juul, Svane, M. S. & Madsbad, Sten, 2020, In: Diabetologia. 63, Suppl. 1, p. S203 1 p., 411.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Signs of a Glucose- and Insulin-Independent Gut-Bone Axis and Aberrant Bone Homeostasis in Type 1 Diabetes
Hartmann, Bolette, Longo, M., Mathiesen, D. S., Hare, Kristine Juul, Jørgensen, Niklas Rye, Esposito, K., Deacon, Carolyn F., Vilsbøll, Tina, Holst, Jens Juul & Knop, Filip Krag, 2024, In: Journal of Clinical Endocrinology and Metabolism. 109, 1, p. e259-e265 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dipeptidyl peptidase IV inhibition enhances the intestinotrophic effect of glucagon-like peptide-2 in rats and mice
Hartmann, Bolette, Thulesen, J., Kissow, Hannelouise, Thulesen, S., Ørskov, Cathrine, Ropke, C., Poulsen, Steen Seier & Holst, Jens Juul, 2000, In: Endocrinology. 141, 11, p. 4013-20 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Glucagon-Like Peptide 2 Inhibits Postprandial Gallbladder Emptying in Man: A Randomized, Double-Blinded, Crossover Study
Hansen, N. L., Brønden, Andreas, Nexoe-Larsen, C. C., Christensen, A. S., Sonne, D. P., Rehfeld, Jens Frederik, Albrechtsen, Nicolai Jacob Wewer, Hartmann, Bolette, Vilsbøll, Tina, Holst, Jens Juul & Knop, Filip Krag, 2020, In: Clinical and Translational Gastroenterology. 11, 12, 9 p., e00257.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Important species differences regarding lymph contribution to gut hormone responses
Hansen, M., Hjøllund, K. R., Hartmann, Bolette, Plamboeck, A., Deacon, Carolyn F., Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, Sep 2015, In: Peptides. 71, p. 28-31 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-1 secretion is influenced by perfusate glucose concentration and by a feedback mechanism involving somatostatin in isolated perfused porcine ileum
Hansen, L., Hartmann, Bolette, Mineo, H. & Holst, Jens Juul, 15 Apr 2004, In: Regulatory Peptides. 118, 1-2, p. 11-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A low-gluten diet induces changes in the intestinal microbiome of healthy Danish adults
Hansen, L. B. S., Roager, H. M., Søndertoft, N. B., Gøbel, R. J., Kristensen, M. B., Vallès-Colomer, M., Vieira-Silva, S., Ibrügger, S., Lind, M. V., Mærkedahl, R. B., Bahl, M. I., Madsen, M. L., Havelund, J., Falony, G., Tetens, I., Nielsen, T., Allin, K. H., Frandsen, H. L., Hartmann, B., Holst, J. J. & 32 others, , 2018, In: Nature Communications. 9, 13 p., 4630.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Acute effects of glucagon-like peptide-1, GLP-19-36 amide, and exenatide on mesenteric blood flow, cardiovascular parameters, and biomarkers in healthy volunteers
Hansen, Lasse Bremholm, Andersen, U. B., Hornum, Mads, Hilsted, L., Veedfald, S., Hartmann, Bolette & Holst, Jens Juul, Feb 2017, In: Physiological Reports. 5, 4, 12 p., e13102.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Combined N-terminal and C-terminal truncations of Glucose dependent Insulinotropic Polypeptide (GIP) are potent and efficient GIP receptor antagonists
Hansen, L. S., wbf943, wbf943, Svendsen, B., Christensen, M., Hartmann, Bolette, Knop, Filip Krag, Holst, Jens Juul & Rosenkilde, Mette, Sep 2015, In: Diabetologia. 58, 1 supplement, p. S276-S277 2 p., 569.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
N- and C-terminally truncated forms of glucose-dependent insulinotropic polypeptide are high-affinity competitive antagonists of the human GIP receptor
Hansen, L. S., wbf943, wbf943, Christensen, M., Knop, Filip Krag, Hartmann, Bolette, Holst, Jens Juul & Rosenkilde, Mette, Mar 2016, In: British Journal of Pharmacology. 173, 5, p. 826-838 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Liraglutide-Induced Weight Loss May be Affected by Autonomic Regulation in Type 1 Diabetes
Hansen, C. S., Frandsen, C. S., Fleischer, J., Vistisen, D., Holst, Jens Juul, Tarnow, L., Knop, Filip Krag, Madsbad, Sten, Andersen, H. U. & Dejgaard, T. F., 2019, In: Frontiers in Endocrinology. 10, 9 p., 242.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rapid gut growth but persistent delay in digestive function in the postnatal period of preterm pigs
Hansen, C. F., Thymann, Thomas, Andersen, A. D., Holst, Jens Juul, Hartmann, Bolette, Hilsted, Linda, Langhorn, L., Jelsing, J. & Sangild, Per Torp, 28 Jan 2016, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 310, 8, p. G550-560 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Studies in Rats of Combined Muscle and Liver Perfusion and of Muscle Extract Indicate That Contractions Release a Muscle Hormone Directly Enhancing Hepatic Glycogenolysis
Han, X. X., Holst, Jens Juul & Galbo, Henrik, 2022, In: Journal of Personalized Medicine. 12, 5, 12 p., 837.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-Like Peptide-1 Inhibits Prandial Gastrointestinal Motility Through Myenteric Neuronal Mechanisms in Humans
Halim, M. A., Degerblad, M., Sundbom, M., Karlbom, U., Holst, Jens Juul, Webb, D. & Hellstrom, P. M., 2018, In: Journal of Clinical Endocrinology & Metabolism. 103, 2, p. 575-585Research output: Contribution to journal › Journal article › Research › peer-review
- Published
LEAP2 reduces postprandial glucose excursions and ad libitum food intake in healthy men
Hagemann, C. A., Jensen, M. S., Holm, Stephanie Kjærulff, Gasbjerg, Lærke Smidt, Byberg, Sarah, Skov-Jeppesen, Kirsa, Hartmann, Bolette, Holst, Jens Juul, Dela, Flemming, Vilsbøll, Tina, Christensen, Mikkel Bring, Holst, Birgitte & Knop, Filip Krag, 2022, In: Cell Reports Medicine. 3, 4, 100582.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exercise-related hypoglycaemia induces QTc-interval prolongation in individuals with type 1 diabetes
Hagelqvist, P. G., Andersen, A., Maytham, K. B., Andreasen, C. R., Engberg, S., Lindhardt, T. B., Faber, Jens, Holst, Jens Juul, Forman, Julie Lyng, Pedersen-Bjergaard, Ulrik, Knop, Filip Krag & Vilsbøll, Tina, 2023, In: Diabetes, Obesity and Metabolism. 25, 5, p. 1186-1195 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Short-term administration of glucagon-like peptide-2. Effects on bone mineral density and markers of bone turnover in short-bowel patients with no colon
Haderslev, Kent Valentin, Jeppesen, Palle Bekker, Hartmann, Bolette, Thulesen, J., Sorensen, H. A., Graff, J., Tofteng, F., Poulsen, S. S., Madsen, J. L., Holst, Jens Juul, Staun, Michael, Mortensen, P. B. & Poulsen, Steen Seier, 1 Apr 2002, In: Scandinavian Journal of Gastroenterology. 37, 4, p. 392-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Can Metabolite and Hormone Profiles Provide a Rationale for Choosing Between Bariatric Procedures?
Guimarães, M., Pereira, S. S., Holst, Jens Juul, Nora, M. & Monteiro, M. P., 2021, In: Obesity Surgery. 31, p. 2174-2179Research output: Contribution to journal › Journal article › Research › peer-review
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Meal induced gut hormone secretion is altered in aerobically trained compared to sedentary young healthy males
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Whole grain-rich diet reduces body weight and systemic low-grade inflammation without inducing major changes of the gut microbiome: a randomised cross-over trial
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Glucagon-like peptide 1 (GLP-1)
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Determinants of plasma levels of proglucagon and the metabolic impact of glucagon receptor signalling: a UK Biobank study
Research output: Contribution to journal › Journal article › Research › peer-review
Signs of a Glucose- and Insulin-Independent Gut-Bone Axis and Aberrant Bone Homeostasis in Type 1 Diabetes
Research output: Contribution to journal › Journal article › Research › peer-review
Exercise-induced increase in muscle insulin sensitivity in men is amplified when assessed using a meal test
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