Secretion and Impact of Gut Hormones in Obesity and Diabetes

Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

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Secretion and Impact of Gut Hormones in Obesity and Diabetes. / Holst, Jens J.

Encyclopedia of Cell Biology: Systems, Translational and Specialized Cell Aspects of Cell Biology. ed. / Ralph A. Bradshaw; Gerald W. Hart; Philip D. Stahl. Vol. 6 2. ed. Elsevier, 2023. p. 543-550.

Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

Harvard

Holst, JJ 2023, Secretion and Impact of Gut Hormones in Obesity and Diabetes. in RA Bradshaw, GW Hart & PD Stahl (eds), Encyclopedia of Cell Biology: Systems, Translational and Specialized Cell Aspects of Cell Biology. 2 edn, vol. 6, Elsevier, pp. 543-550. https://doi.org/10.1016/B978-0-12-821618-7.00264-9

APA

Holst, J. J. (2023). Secretion and Impact of Gut Hormones in Obesity and Diabetes. In R. A. Bradshaw, G. W. Hart, & P. D. Stahl (Eds.), Encyclopedia of Cell Biology: Systems, Translational and Specialized Cell Aspects of Cell Biology (2 ed., Vol. 6, pp. 543-550). Elsevier. https://doi.org/10.1016/B978-0-12-821618-7.00264-9

Vancouver

Holst JJ. Secretion and Impact of Gut Hormones in Obesity and Diabetes. In Bradshaw RA, Hart GW, Stahl PD, editors, Encyclopedia of Cell Biology: Systems, Translational and Specialized Cell Aspects of Cell Biology. 2 ed. Vol. 6. Elsevier. 2023. p. 543-550 https://doi.org/10.1016/B978-0-12-821618-7.00264-9

Author

Holst, Jens J. / Secretion and Impact of Gut Hormones in Obesity and Diabetes. Encyclopedia of Cell Biology: Systems, Translational and Specialized Cell Aspects of Cell Biology. editor / Ralph A. Bradshaw ; Gerald W. Hart ; Philip D. Stahl. Vol. 6 2. ed. Elsevier, 2023. pp. 543-550

Bibtex

@inbook{624267b75ac4424a914f3e31b487108b,
title = "Secretion and Impact of Gut Hormones in Obesity and Diabetes",
abstract = "Gut hormones, otherwise known for their actions on the gastrointestinal tract, have important roles in the regulation of both metabolism and food intake. Insulin-stimulating incretin hormones, GLP-1 and GIP, are responsible for disposal of up to 80% of an oral glucose load, thereby preventing postprandial hyperglycemia (an established cardiovascular risk factor). Absence of the incretin effect leads to overt glucose intolerance. Gut hormones may influence energy balance which has led to investigation of the possible involvement of these hormones and their secretion in the pathogenesis of these diseases. In this short overview, we will discuss some key observations regarding these features with an emphasis on human conditions.",
keywords = "Bariatric surgery, Ghrelin, GIP, Glicentin, Glucagon-like peptide-1. GLP-1, Glucose-dependent insulinotropic polypeptide, LEAP2, Oxyntomodulin, Peptide YY, PYY",
author = "Holst, {Jens J.}",
note = "Publisher Copyright: {\textcopyright} 2023 Elsevier Inc. All rights reserved.",
year = "2023",
doi = "10.1016/B978-0-12-821618-7.00264-9",
language = "English",
isbn = "978-0-12-821624-8",
volume = "6",
pages = "543--550",
editor = "Bradshaw, {Ralph A.} and Hart, {Gerald W.} and Stahl, {Philip D.}",
booktitle = "Encyclopedia of Cell Biology",
publisher = "Elsevier",
address = "Netherlands",
edition = "2",

}

RIS

TY - CHAP

T1 - Secretion and Impact of Gut Hormones in Obesity and Diabetes

AU - Holst, Jens J.

N1 - Publisher Copyright: © 2023 Elsevier Inc. All rights reserved.

PY - 2023

Y1 - 2023

N2 - Gut hormones, otherwise known for their actions on the gastrointestinal tract, have important roles in the regulation of both metabolism and food intake. Insulin-stimulating incretin hormones, GLP-1 and GIP, are responsible for disposal of up to 80% of an oral glucose load, thereby preventing postprandial hyperglycemia (an established cardiovascular risk factor). Absence of the incretin effect leads to overt glucose intolerance. Gut hormones may influence energy balance which has led to investigation of the possible involvement of these hormones and their secretion in the pathogenesis of these diseases. In this short overview, we will discuss some key observations regarding these features with an emphasis on human conditions.

AB - Gut hormones, otherwise known for their actions on the gastrointestinal tract, have important roles in the regulation of both metabolism and food intake. Insulin-stimulating incretin hormones, GLP-1 and GIP, are responsible for disposal of up to 80% of an oral glucose load, thereby preventing postprandial hyperglycemia (an established cardiovascular risk factor). Absence of the incretin effect leads to overt glucose intolerance. Gut hormones may influence energy balance which has led to investigation of the possible involvement of these hormones and their secretion in the pathogenesis of these diseases. In this short overview, we will discuss some key observations regarding these features with an emphasis on human conditions.

KW - Bariatric surgery

KW - Ghrelin

KW - GIP

KW - Glicentin

KW - Glucagon-like peptide-1. GLP-1

KW - Glucose-dependent insulinotropic polypeptide

KW - LEAP2

KW - Oxyntomodulin

KW - Peptide YY

KW - PYY

U2 - 10.1016/B978-0-12-821618-7.00264-9

DO - 10.1016/B978-0-12-821618-7.00264-9

M3 - Book chapter

AN - SCOPUS:85159031696

SN - 978-0-12-821624-8

VL - 6

SP - 543

EP - 550

BT - Encyclopedia of Cell Biology

A2 - Bradshaw, Ralph A.

A2 - Hart, Gerald W.

A2 - Stahl, Philip D.

PB - Elsevier

ER -

ID: 381509278