- 2009
- Published
Mutations in the VNTR of the carboxyl-ester lipase gene (CEL) are a rare cause of monogenic diabetes
Torsvik, J., Johansson, S., Johansen, A., Ek, J., Minton, J., Raeder, H., Ellard, S., Hattersley, A., Pedersen, Oluf Borbye, Hansen, T., Molven, A. & Njølstad, P. R., 2009, In: Human Genetics. 127, 1, p. 55-64 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Validation of a multimarker model for assessing risk of type 2 diabetes from a five-year prospective study of 6784 Danish people (Inter99)
Urdea, M., Kolberg, J., Wilber, J., Gerwien, R., Moler, E., Rowe, M., Jorgensen, P., Hansen, T., Pedersen, Oluf Borbye, Jørgensen, T. & Borch-Johnsen, K., 2009, In: Journal of Diabetes Science and Technology. 3, 4, p. 748-55 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bleeding peptic ulcer. Prevalence of Helicobacter pylori and use of nonsteroidal anti-inflammatory drugs/acetylsalicylic acid
Vestergard, A., Bredahl, K., Muckadell, O. B. D., Pedersen, Oluf Borbye & Hansen, J. M., 2009, In: Ugeskrift for læger. 171, 4, p. 235-239 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impaired Insulin-Mediated Phosphorylation of Skeletal Muscle TBC1D4 at Multiple Sites in Type 2 Diabetes. Effect of Endurance Training on TBC1D4 Protein and Phosphorylation
Vind, B. F., Pehmoller, C., Treebak, Jonas Thue, Birk, Jesper Bratz, Hey-Mogensen, M., Beck-Nielsen, H., Wojtaszewski, Jørgen F P & Hojlund, K., 2009, In: Diabetes.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fatness-associated FTO gene variant increases mortality independent of fatness--in cohorts of Danish men
Zimmermann, E., Kring, S. I. I., Berentzen, T. L., Holst, C., Pers, T. H., Hansen, Torben, Pedersen, Oluf Borbye, Sørensen, Thorkild I.A. & Jess, T., 2009, In: PLoS ONE. 4, 2, p. e4428Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Variation in the gene encoding Kruppel-like factor 7 influences body fat: studies of 14,818 Danes
Zobel, D., Andreasen, C., Burgdorf, K., Andersson, E., Sandbæk, A., Lauritzen, T., Borch-Johnsen, K., Jørgensen, T., Maeda, S., Nakamura, Y., Eiberg, Hans Rudolf Lytchoff, Pedersen, Oluf Borbye & Hansen, Torben, 2009, In: European Journal of Endocrinology. 160, 4, p. 603-9Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Variants near MC4R associate with obesity and influence obesity-related quantitative traits in a population of middle-aged people: studies of 14,940 Danes
Zobel, D. P., Andreasen, C. H., Grarup, N., Eiberg, Hans Rudolf Lytchoff, Sørensen, Thorkild I.A., Sandbæk, A., Lauritzen, T., Borch-Johnsen, K., Jørgensen, T., Pedersen, Oluf Borbye & Hansen, T., 2009, In: Diabetes. p. 757-764 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2010
- Published
Maternal postpartum distress and childhood overweight
Adeltoft, T. A., Andersen, C. S., Ingstrup, K. G., Nohr, E. A., Sørensen, Thorkild I.A. & Sørensen, Thorkild I.A., 1 Jan 2010, In: P L o S One. 5, 6, p. e11136Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetics of type 2 diabetes.
Ahlqvist, E., Ahluwalia, Tarun Veer Singh & Groop, L., 30 Nov 2010, In: Clinical Chemistry.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Insulin resistance induced by physical inactivity is associated with multiple transcriptional changes in skeletal muscle in young men
Alibegovic, A. C., Sonne, M. P., Højbjerre, L., Bork-Jensen, J., Jacobsen, S., Nilsson, E., Faerch, K., Hiscock, N., Mortensen, B., Friedrichsen, M., Stallknecht, Bente Merete, Dela, Flemming & Vaag, Allan, 1 Nov 2010, In: American Journal of Physiology: Endocrinology and Metabolism. 299, 5, p. E752-63 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The T-allele of TCF7L2 rs7903146 associates with a reduced compensation of insulin secretion for insulin resistance induced by 9 days of bed rest
Alibegovic, A. C., Sonne, M. P., Højbjerre, L., Hansen, T., Pedersen, Oluf Borbye, van Hall, Gerrit, Holst, Jens Juul, Stallknecht, Bente Merete, Dela, Flemming & Vaag, A., 2010, In: Diabetes. 59, 4, p. 836-43 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prenatal exposures to perfluorinated chemicals and anthropometric measures in infancy
Andersen, C. S., Fei, C., Gamborg, Michael Orland, Nohr, E. A., Sørensen, Thorkild I.A. & Olsen, J., 1 Dec 2010, In: American Journal of Epidemiology. 172, 11, p. 1230-7 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Birth weight, childhood body mass index and risk of coronary heart disease in adults: combined historical cohort studies
Andersen, L. G., Ängquist, Lars, Eriksson, J. G., Forsen, T., Gamborg, Michael Orland, Osmond, C., Baker, J. L. & Sørensen, Thorkild I.A., 1 Jan 2010, In: P L o S One. 5, 11, p. e14126Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Latent autoimmune diabetes in adults differs genetically from classical type 1 diabetes diagnosed after the age of 35 years
Lepola, Mette Andersen, Lundgren, V., Turunen, J. A., Forsblom, C., Isomaa, B., Groop, P. H., Groop, L. & Tuomi, T., 1 Sep 2010, In: Diabetes Care. 33, 9, p. 2062-2064 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Type 2 diabetes risk alleles near ADCY5, CDKAL1 and HHEX-IDE are associated with reduced birthweight
Andersson, E. A., Pilgaard, K., Pisinger, C., Harder, M. N., Grarup, N., Faerch, K., Poulsen, P., Witte, D. R., Jørgensen, T., Vaag, Allan, Hansen, Torben & Pedersen, Oluf Borbye, 1 Sep 2010, In: Diabetologia. 53, 9, p. 1908-16 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Do gene variants influencing adult adiposity affect birth weight? A population-based study of 24 loci in 4,744 Danish individuals
Andersson, E. A., Pilgaard, K., Pisinger, C., Harder, M. N., Grarup, N., Færch, K., Sandholt, C., Poulsen, P., Witte, D. R., Jørgensen, T., Vaag, Allan, Pedersen, Oluf Borbye & Hansen, T., 1 Jan 2010, In: P L o S One. 5, 12, p. e14190Research output: Contribution to journal › Journal article › Research › peer-review
- Published
MTNR1B G24E variant associates With BMI and fasting plasma glucose in the general population in studies of 22,142 Europeans
Andersson, E. A., Holst, Birgitte, Sparsø, T., Grarup, N., Banasik, Karina, Holmkvist, J., Jørgensen, T., Borch-Johnsen, K., Egerod, Kristoffer Lihme, Lauritzen, T., Sørensen, Thorkild I.A., Bonnefond, A., Meyre, D., Froguel, P., Schwartz, Thue W., Pedersen, Oluf Borbye & Hansen, Torben, 2010, In: Diabetes. 59, 6, p. 1539-48 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
SmashCommunity: A metagenomic annotation and analysis tool.
Arumugam, Mani, Harrington, E. D., Foerstner, K. U., Raes, J. & Bork, P., Oct 2010, In: Bioinformatics. 26, 23, p. 2977-2978 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The chemistry of life: Four chapters in the history of metabolic research
Bencard, Adam, 2010Research output: Non-textual form › 2D/3D (psysical products) › Communication
- Published
Changes in waist circumference and mortality in middle-aged men and women
Berentzen, T. L., Jakobsen, M. U., Halkjaer, J., Tjønneland, A., Overvad, K. & Sørensen, Thorkild I.A., 1 Jan 2010, In: P L o S One. 5, 9Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bed Rest-Induced Changes in TBC1D4 Phosphorylation and Glycogen Synthase Activity. Effects of Acute Exercise
Bienso, R. S., Ringholm, S., Lundby, C., Achman-Andersen, N. J., Plomgaard, Peter Stendahl, Krogh-Madsen, Rikke, Kiilerich, K., Guerra, B., Treebak, Jonas Thue, Calbet, J. A., Pilegaard, Henriette & Wojtaszewski, J. J. F., 2010, In: Diabetes.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of lifestyle aspects on the association of body size and shape with all-cause mortality in middle-aged men and women
Bigaard, J., Christensen, J., Tjønneland, A., Thomsen, B. L. R., Overvad, K. & Sørensen, Thorkild I.A., 1 Aug 2010, In: Obesity Facts. 3, 4, p. 252-60 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Variants at DGKB/TMEM195, ADRA2A, GLIS3 and C2CD4B loci are associated with reduced glucose-stimulated beta cell function in middle-aged Danish people
Boesgaard, T. W., Grarup, N., Jørgensen, T., Borch-Johnsen, K., Hansen, Torben, Pedersen, Oluf Borbye & Meta-Analysis of Glucose and Insulin-Related Trait Consortium (MAGIC), M. O. G. A. I. T. C. (., 1 Aug 2010, In: Diabetologia. 53, 8, p. 1647-55 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Further evidence that mutations in INS can be a rare cause of Maturity-Onset Diabetes of the Young (MODY)
Boesgaard, T. W., Pruhova, S., Andersson, E. A., Cinek, O., Obermannova, B., Lauenborg, J., Damm, Peter, Bergholdt, R., Pociot, Flemming, Pisinger, C., Barbetti, F., Lebl, J., Pedersen, Oluf Borbye & Hansen, Torben, 1 Jan 2010, In: B M C Medical Genetics. 11, p. 42Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High body mass index in adolescent girls precedes psoriasis hospitalization
Bryld, L. E., Sørensen, Thorkild I.A., Andersen, K. K., Jemec, G. & Baker, J. L., 1 Sep 2010, In: Acta Dermato Venereologica. 90, 5, p. 488-93 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A novel intronic peroxisome proliferator-activated receptor gamma enhancer in the uncoupling protein (UCP) 3 gene as a regulator of both UCP2 and -3 expression in adipocytes
Bugge, A. S., Siersbaek, M., Madsen, M. S., Göndör, A., Rougier, C. & Mandrup, S., 4 Jun 2010, In: The Journal of Biological Chemistry. 285, 23, p. 17310-7 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular Mechanisms and Genome-Wide Aspects of PPAR Subtype Specific Transactivation
Bugge, A. S. & Mandrup, S., 2010, In: PPAR Research. 2010Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Studies of association between LPIN1 variants and common metabolic phenotypes among 17,538 Danes
Burgdorf, K. S., Sandholt, C. H., Sparsø, T., Andersen, G., Witte, D. R., Jørgensen, T., Sandbaek, A., Lauritzen, T., Sørensen, Thorkild I.A., Madsbad, Sten, Hansen, Torben & Pedersen, Oluf Borbye, 1 Jul 2010, In: European Journal of Endocrinology. 163, 1, p. 81-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interdependence of AMPK and SIRT1 for metabolic adaptation to fasting and exercise in skeletal muscle
Cantó, C., Jiang, L. Q., Deshmukh, Atul Shahaji, Mataki, C., Coste, A., Lagouge, M., Zierath, Juleen R & Auwerx, J., 3 Mar 2010, In: Cell Metabolism. 11, 3, p. 213-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Obesity-related polymorphisms and their associations with the ability to regulate fat oxidation in obese europeans: The NUGENOB Study
Corpeleijn, E., Petersen, L., Holst, C., Saris, W. H., Astrup, A., Langin, D., Macdonald, I., Martinez, J. A., Oppert, J., Polak, J., Pedersen, Oluf Borbye, Froguel, P., Arner, P., Sørensen, Thorkild I.A. & Blaak, E. E., 2010, In: Obesity. 18, 7, p. 1369-1377 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nitric oxide increases cyclic GMP levels, AMP-activated protein kinase (AMPK)alpha1-specific activity and glucose transport in human skeletal muscle
Deshmukh, Atul Shahaji, Long, Y. C., de Castro Barbosa, T., Karlsson, H. K. R., Glund, S., Zavadoski, W. J., Gibbs, E. M., Koistinen, H. A., Wallberg-Henriksson, H. & Zierath, Juleen R, Jun 2010, In: Diabetologia. 53, 6, p. 1142-50 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nutrient-dependent regulation of PGC-1α's acetylation state and metabolic function through the enzymatic activities of Sirt1/GCN5
Dominy, J. E., Lee, Y., Gerhart-Hines, Zach & Puigserver, P., Aug 2010, In: Biochimica et Biophysica Acta - Proteins and Proteomics. 1804, 8, p. 1676-1683 8 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Dietary fiber and subsequent changes in body weight and waist circumference in European men and women
Du, H., van der A, D. L., Boshuizen, H. C., Forouhi, N. G., Wareham, N. J., Halkjaer, J., Tjønneland, A., Overvad, K., Jakobsen, M. U., Boeing, H., Buijsse, B., Masala, G., Palli, D., Sørensen, Thorkild I.A., Saris, W. H. M. & Feskens, E. J. M., 1 Feb 2010, In: American Journal of Clinical Nutrition. 91, 2, p. 329-36 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
Dupuis, J., Langenberg, C., Prokopenko, I., Saxena, R., Soranzo, N., Jackson, A. U., Wheeler, E., Glazer, N. L., Bouatia-Naji, N., Gloyn, A. L., Lindgren, C. M., Mägi, R., Morris, A. P., Randall, J., Johnson, T., Elliott, P., Rybin, D., Thorleifsson, G., Steinthorsdottir, V., Henneman, P. & 31 others, , 1 Feb 2010, In: Nature Genetics. 42, 2, p. 105-16 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differential incretin effects of GIP and GLP-1 on gastric emptying, appetite, and insulin-glucose homeostasis
Edholm, T., Degerblad, M., Grybäck, P., Hilsted, Linda, Holst, Jens Juul, Jacobsson, H., Efendic, S., Schmidt, P. T. & Hellström, P. M., 1 Nov 2010, In: Neurogastroenterology and Motility Online. 22, 11, p. 1191-200, e315 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Neuroscience evidence should be incorporated into our ethical practices
Felsen, G., Whiteley, Louise, Nadler, R. & Reiner, P. B., 2010, In: A J O B Neuroscience. 1, 4, p. 36-38Research output: Contribution to journal › Comment/debate › Communication
- Published
Effects of category-specific costs on neural systems for perceptual decision-making
Fleming, S. M., Whiteley, Louise, Hulme, O. J., Sahani, M. & Dolan, R. J., 2010, In: Journal of Neurology & Neurophysiology. 103, 6, p. 3238-47 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differential aetiology and impact of phosphoinositide 3-kinase (PI3K) and Akt signalling in skeletal muscle on in vivo insulin action
Friedrichsen, M., Poulsen, P., Richter, Erik A., Hansen, B. F., Birk, Jesper Bratz, Ribel-Madsen, R., Stender-Petersen, K., Nilsson, E., Beck-Nielsen, H., Vaag, Allan & Wojtaszewski, Jørgen F P, 2010, In: Diabetologia. 53, 9, p. 1998-2007 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Family and population-based studies of variation within the ghrelin receptor locus in relation to measures of obesity
Gjesing, A. P., Larsen, L. H., Torekov, S. S., Hainerová, I. A., Kapur, R., Johansen, A., Albrechtsen, A., Boj, S., Holst, B., Harper, A., Urhammer, S. A., Borch-Johnsen, K., Pisinger, C. H., Echwald, S. M., Eiberg, H. R. L., Astrup, A., Lebl, J., Ferrer, J., Schwartz, T. W., Hansen, T. & 1 others, , 2010, In: P L o S One. 5, 4, 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Physiologic characterization of type 2 diabetes-related loci
Grarup, N., Sparsø, T. & Hansen, Torben, 1 Dec 2010, In: Current Diabetes Reports. 10, 6, p. 485-97 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
TCF7L2 rs7903146-macronutrient interaction in obese individuals' responses to a 10-wk randomized hypoenergetic diet
Grau, K., Cauchi, S., Holst, C., Astrup, A., Martinez, J. A., Saris, W. H. M., Blaak, E. E., Oppert, J., Arner, P., Rössner, S., Macdonald, I. A., Klimcakova, E., Langin, D., Pedersen, Oluf Borbye, Froguel, P. & Sørensen, Thorkild I.A., 2010, In: American Journal of Clinical Nutrition. 91, 2, p. 472-479 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide association study identifies a sequence variant within the DAB2IP gene conferring susceptibility to abdominal aortic aneurysm
Gretarsdottir, S., Baas, A. F., Thorleifsson, G., Holm, H., den Heijer, M., de Vries, J-P. P. M., Kranendonk, S. E., Zeebregts, C. J. A. M., van Sterkenburg, S. M., Geelkerken, R. H., van Rij, A. M., Williams, M. J. A., Boll, A. P. M., Kostic, J. P., Jonasdottir, A., Jonasdottir, A., Walters, G. B., Masson, G., Sulem, P., Saemundsdottir, J. & 82 others, , 1 Aug 2010, In: Nature Genetics. 42, 8, p. 692-7 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Neuronal calcium sensor synaptotagmin-9 is not involved in the regulation of glucose homeostasis or insulin secretion
Gustavsson, N., Wang, X., Wang, Y., Seah, T., Xu, J., Radda, G. K., Südhof, T. C. & Han, W., 9 Nov 2010, In: PLOS ONE. 5, 11, p. e15414Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Treatment of insulin resistance and obesity by stimulating GLP-1 release
Hansen, Harald S., Diep, T. A., Holst, Jens Juul, Rosenkilde, Mette & Andersen, N. W., 29 Dec 2010, IPC No. A61K 31/23, Patent No. PCT/DK2010/050161, 24 Jun 2010Research output: Patent
- Published
SmashCell: A software framework for the analysis of single-cell amplified genome sequences.
Harrington, E. D., Arumugam, Mani, Raes, J., Bork, P. & Relman, D. A., Oct 2010, In: Bioinformatics. 26, 23, p. 2979-2980 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Associations between dietary intake and body fat independent of genetic and familial environmental background
Hasselbalch, A. L., Heitmann, B. L., Kyvik, K. O. & Sørensen, Thorkild I.A., 1 May 2010, In: International Journal of Obesity. 34, 5, p. 892-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Twin study of heritability of eating bread in Danish and Finnish men and women
Hasselbalch, A. L., Silventoinen, K., Keskitalo, K., Pietiläinen, K. H., Rissanen, A., Heitmann, B. L., Kyvik, K. O., Sørensen, Thorkild I.A. & Kaprio, J., 1 Apr 2010, In: Twin Research and Human Genetics. 13, 2, p. 163-7 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution
Heid, I. M., Jackson, A. U., Randall, J. C., Winkler, T. W., Qi, L., Steinthorsdottir, V., Thorleifsson, G., Zillikens, M. C., Speliotes, E. K., Mägi, R., Workalemahu, T., White, C. C., Bouatia-Naji, N., Harris, T. B., Berndt, S. I., Ingelsson, E., Willer, C. J., Weedon, M. N., Luan, J., Vedantam, S. & 31 others, , 1 Nov 2010, In: Nature Genetics. 42, 11, p. 949-60 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A conserved aromatic lock for the tryptophan rotameric switch in TM-VI of seven-transmembrane receptors
Holst, Birgitte, Nygaard, R., Hansen, L. V., Bach, Anders, Engelstoft, M. S., Petersen, P. S., Frimurer, T. M. & Schwartz, Thue W., 2010, In: Journal of Biological Chemistry. 285, 6, p. 3973-85 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Kardiale virkninger af glukagonlignende peptid 1
Holst, Jens Juul, 11 Oct 2010, In: Ugeskrift for Laeger. 172, 41, p. 2821 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
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Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets
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The isoenzyme pattern of LDH does not play a physiological role; except perhaps during fast transitions in energy metabolism
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Determinants of plasma levels of proglucagon and the metabolic impact of glucagon receptor signalling: a UK Biobank study
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Targeting postsynaptic glutamate receptor scaffolding proteins PSD-95 and PICK1 for obesity treatment
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