Novo Nordisk Foundation Center for Basic Metabolic Research

  1. 2011
  2. Published

    Childhood overweight after establishment of the gut microbiota: the role of delivery mode, pre-pregnancy weight and early administration of antibiotics

    Adeltoft, T. A., Andersen, C. S., Gamborg, Michael Orland, Sørensen, Thorkild I.A. & Riis, J. T., 1 Apr 2011, In: International Journal of Obesity. 35, 4, p. 522-9 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Common variants in CNDP1 and CNDP2, and risk of nephropathy in type 2 diabetes.

    Ahluwalia, Tarun Veer Singh, Lindholm, E. & Groop, L., 15 May 2011, In: Diabetologia.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Uromodulin gene variant is associated with type 2 diabetic nephropathy.

    Ahluwalia, Tarun Veer Singh, Groop, L. & Melander, O., 29 Sep 2011, In: Journal of Hypertension.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    C-reactive protein and cancer

    Allin, K. H., 2011, Faculty of Health Sciences, University of Copenhagen.

    Research output: Book/ReportPh.D. thesis

  6. Published

    Insight into structure and assembly of the nuclear pore complex by utilizing the genome of a eukaryotic thermophile

    Amlacher, S., Sarges, P., Flemming, D., van Noort, V., Kunze, R., Devos, D. P., Arumugam, Mani, Bork, P. & Hurt, E., 2011, In: Cell. 146, 2, p. 277-89 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Weight gain in different periods of pregnancy and offspring's body mass index at 7 years of age

    Andersen, C. S., Gamborg, M., Sørensen, Thorkild I.A. & Nohr, E. A., 2011, In: International Journal of Pediatric Obesity. 6, 2-2, p. e179-86

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    The Birth Weight Lowering C-Allele of rs900400 Near LEKR1 and CCNL1 Associates with Elevated Insulin Release following an Oral Glucose Challenge

    Andersson, E. A., Harder, M. N., Pilgaard, K., Pisinger, C., Stancáková, A., Kuusisto, J., Grarup, N., Færch, K., Poulsen, P., Witte, D. R., Jørgensen, T., Vaag, Allan, Laakso, M., Pedersen, Oluf Borbye & Hansen, Torben, Nov 2011, In: P L o S One. 6, 11, p. e27096 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Enterotypes of the human gut microbiome: [Plus]Corrigendum [Plus]Addendum

    Arumugam, M., Raes, J., Pelletier, E., Le Paslier, D., Yamada, T., Mende, D. R., Fernandes, G. R., Tap, J., Bruls, T., Batto, J-M., dos Santos, M. B. Q., Borruel, N., Casellas, F., Fernandez, L., Gautier, L., Hansen, T., Hattori, M., Hayashi, T., Kleerebezem, M., Kurokawa, K. & 31 others, Leclerc, M., Levenez, F., Manichanh, C., Nielsen, H. B., Nielsen, T., Pons, N., Poulain, J., Qin, J., Sicheritz-Ponten, T., Tims, S., Torrents, D., Ugarte, E., Zoetendal, E. G., Wang, J., Guarner, F., Pedersen, Oluf Borbye, de Vos, W. M., Brunak, Søren, Doré, J., Antolín, M., Artiguenave, F., Blottiere, H. M., Almeida, M., Brechot, C., Cara, C., Chervaux, C., Cultrone, A., Delorme, C., Denariaz, G., Kristiansen, Karsten & MetaHIT Consortium, M. C., 2011, In: Nature. 473, 7346, p. 174-180 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Glucagon antagonism as a potential therapeutic target in type 2 diabetes

    Bagger, J. I., Knop, Filip Krag, Holst, Jens Juul & Vilsbøll, Tina, Nov 2011, In: Diabetes, Obesity and Metabolism. 13, 11, p. 965-971 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Impaired regulation of the incretin effect in patients with type 2 diabetes

    Bagger, J. I., Knop, Filip Krag, Lund, Asger Bach, drb459, drb459, Holst, Jens Juul & Vilsbøll, Tina, 2011, In: Journal of Clinical Endocrinology and Metabolism. 96, 3, p. 737-45 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Obesity research based on the Copenhagen School Health Records Register

    Baker, J. L. & Sørensen, Thorkild I.A., 2011, In: Scandinavian Journal of Public Health. Supplement. 39, 7 Suppl, p. 196-200 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Bioinformatics-driven identification and examination of candidate genes for non-alcoholic fatty liver disease

    Banasik, Karina, Justesen, Johanne Marie, Hornbak, M., Krarup, N. T., Gjesing, A. P., Sandholt, C. H., Søndergaard Jensen, T., Grarup, N., Andersson, Åsa, Jørgensen, T., Witte, D. R., Sandbæk, A., Lauritzen, T., Thorens, B., Brunak, Søren, Sørensen, Thorkild I.A., Pedersen, Oluf Borbye & Hansen, Torben, 1 Jan 2011, In: P L o S One. 6, 1, p. e16542

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    The FOXO3A rs2802292 G-Allele Associates with Improved Peripheral and Hepatic Insulin Sensitivity and Increased Skeletal Muscle-FOXO3A mRNA Expression in Twins

    Banasik, Karina, Ribel-Madsen, R., Gjesing, A. P., Wegner, L., Andersson, Åsa, Poulsen, P., Borglykke, A., Witte, D. R., Pedersen, Oluf Borbye, Hansen, Torben & Vaag, Allan, 1 Jan 2011, In: Journal of Clinical Endocrinology and Metabolism. 96, 1, p. E119-24

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    DNA methylation in metabolic disorders

    Barrès, Romain & Zierath, Juleen R, 1 Apr 2011, In: American Journal of Clinical Nutrition. 93, 4, p. 897S-900

    Research output: Contribution to journalReviewResearchpeer-review

  16. Published

    Balance og stofskifte: To forestillinger om kroppen i medicinens historie

    Bencard, Adam, 2011

    Research output: Non-textual form2D/3D (psysical products)Communication

  17. Published

    Changes in waist circumference and the incidence of acute myocardial infarction in middle-aged men and women

    Berentzen, T. L., Jakobsen, M. U., Stegger, J. G., Halkjaer, J., Tjønneland, A., Sørensen, Thorkild I.A. & Overvad, K., 2011, In: P L o S One. 6, 10, p. e26849

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Changes in waist circumference and the incidence of diabetes in middle-aged men and women

    Berentzen, T. L., Jakobsen, M. U., Halkjaer, J., Tjønneland, A., Sørensen, Thorkild I.A. & Overvad, K., 2011, In: P L o S One. 6, 8, p. e23104

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    PKCδ regulates hepatic insulin sensitivity and hepatosteatosis in mice and humans

    Bezy, O., Tran, T. T., Pihlajamäki, J., Suzuki, R., Emanuelli, Brice, Winnay, J., Mori, M. A., Haas, J., Biddinger, S. B., Leitges, M., Goldfine, A. B., Patti, M. E., King, G. L. & Kahn, C. R., Jun 2011, In: The Journal of Clinical Investigation. 121, 6, p. 2504-17 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Implications of central obesity-related variants in LYPLAL1, NRXN3, MSRA, and TFAP2B on quantitative metabolic traits in adult Danes

    Bille, D. S., Banasik, Karina, Justesen, Johanne Marie, Sandholt, C. H., Sandbæk, A., Lauritzen, T., Jørgensen, T., Witte, D. R., Holm, Jens-Christian, Hansen, Torben & Pedersen, Oluf Borbye, 1 Jun 2011, In: P L o S One. 6, 6, p. e20640 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published
  22. Published

    The effect of Glucagon-Like Peptide-2 on mesenteric blood flow and cardiac parameters in end-jejunostomy short bowel patients

    Bremholm, L., Hornum, Mads, Andersen, U. B., Hartmann, Bolette, Holst, Jens Juul & Jeppesen, Palle Bekker, 2011, In: Regulatory Peptides. 168, 1-3, p. 32-8 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Counter-regulatory hormone responses to spontaneous hypoglycaemia during treatment with insulin Aspart or human soluble insulin: a double-blinded randomized cross-over study

    Brock Jacobsen, I., Vind, B. F., Korsholm, L., Flyvbjerg, A., Frystyk, J., Holst, Jens Juul, Beck-Nielsen, H. & Henriksen, J. E., 2011, In: Acta Physiologica (Print). 202, 3, p. 337-347 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Genetic and environmental influences on oxidative damage assessed in elderly Danish twins

    Broedbaek, K., Ribel-Madsen, R., Henriksen, T., Weimann, A., Petersen, M., Andersen, Jon Thor Trærup, Afzal, Shoaib, Hjelvang, B., Roberts, L. J., Vaag, Allan, Poulsen, P. & Poulsen, Henrik Enghusen, 2011, In: Free Radical Biology & Medicine. 50, 11, p. 1488-91 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    LIF is a contraction-induced myokine stimulating human myocyte proliferation

    Broholm, C., Laye, M. J., Brandt, C., Vadalasetty, R., Pilegaard, Henriette, Pedersen, Bente Klarlund & Schéele, Camilla Charlotte Nielsen, 2011, In: Journal of Applied Physiology. 111, 1, p. 251-9 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Child overweight - mothers' competence to take action

    Brødsgaard, A., Wagner, L., Peitersen, B., Poulsen, I. & Sørensen, Thorkild I.A., Aug 2011, In: Obesity Facts. 4, 4, p. 305-11 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Maternal and child awareness and expectations of child overweight

    Brødsgaard, A., Wagner, L., Peitersen, B., Poulsen, I. & Sørensen, Thorkild I.A., 1 Jan 2011, In: Obesity Facts. 4, 4, p. 297-304 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Association studies of novel obesity-related gene variants with quantitative metabolic phenotypes in a population-based sample of 6,039 Danish individuals

    Burgdorf, K. S., Gjesing, A. P., Grarup, N., Justesen, Johanne Marie, Sandholt, C. H., Witte, D. R., Jørgensen, T., Madsbad, Sten, Hansen, Torben & Pedersen, Oluf Borbye, 28 Sep 2011, In: Diabetologia. 55, 1, p. 105-13 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Studies of the Association of Arg72Pro of Tumor Suppressor Protein p53 with Type 2 Diabetes in a Combined Analysis of 55,521 Europeans

    Burgdorf, K. S., Grarup, N., Justesen, Johanne Marie, Harder, M. N., Witte, D. R., Jørgensen, T., Sandbæk, A., Lauritzen, T., Madsbad, Sten, Hansen, Torben, DIAGRAM Consortium, D. C. & Pedersen, Oluf Borbye, 2011, In: P L o S One. 6, 1, p. e15813 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Liraglutide Treatment Is Associated with a Low Frequency and Magnitude of Antibody Formation with No Apparent Impact on Glycemic Response or Increased Frequency of Adverse Events: Results from the Liraglutide Effect and Action in Diabetes (LEAD) trials

    Buse, J. B., Garber, A., Rosenstock, J., Schmidt, W. E., Brett, J. H., Videbæk, N., Holst, Jens Juul & Nauck, M., 2011, In: Journal of Clinical Endocrinology and Metabolism. 96, 6, p. 1695-702 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Glucose-dependent insulinotropic polypeptide: a bifunctional glucose-dependent regulator of glucagon and insulin secretion in humans

    Christensen, M., Vedtofte, L., Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2011, In: Diabetes. 60, 12, p. 3103-9 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Lixisenatide for type 2 diabetes mellitus

    Christensen, M., Knop, Filip Krag, Vilsbøll, Tina & Holst, Jens Juul, 2011, In: Expert Opinion on Investigational Drugs. 20, 4, p. 549-57 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Strenuous physical exercise adversely affects monocyte chemotaxis

    Czepluch, F. S., Barrès, Romain, Caidahl, K., Olieslagers, S., Krook, A., Rickenlund, A., Zierath, Juleen R & Waltenberger, J., Jan 2011, In: Thrombosis and Haemostasis. 105, 1, p. 122-30 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Adipose tissue fatty acid patterns and changes in anthropometry: a cohort study

    Dahm, C. C., Gorst-Rasmussen, A., Jakobsen, M. U., Schmidt, E. B., Tjønneland, A., Sørensen, Thorkild I.A. & Overvad, K., 2011, In: P L o S One. 6, 7, p. e22587

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Treatments and services for neurodevelopmental disorders on advocacy websites: Information or evaluation?

    Di Pietro, N. C., Whiteley, Louise & Illes, J., 2011, In: Neuroethics. 5, 2, p. 197-209 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Nutrient-dependent acetylation controls basic regulatory metabolic switches and cellular reprogramming

    Dominy, J. E., Gerhart-Hines, Zach & Puigserver, P., 2011, In: Cold Spring Harbor Symposia on Quantitative Biology. 76, p. 203-209 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Heritability of optic disc diameters: a twin study

    Drobnjak, D., Taarnhøj, N. C., Mitchell, P., Wang, J. J., Tan, A., Kessel, Line, Hougaard, J., Sørensen, Thorkild I.A. & Larsen, Michael, 1 Mar 2011, In: Acta Ophthamologica (Online). 89, 2, p. e193-8

    Research output: Contribution to journalJournal articleResearch

  38. Published

    Genetic polymorphisms in the hypothalamic pathway in relation to subsequent weight change--the DiOGenes study

    Du, H., Ängquist, Lars, Vimaleswaran, K. S., Hansen, R. D., van der, D. L., Holst, C., Tjønneland, A., Overvad, K., Jakobsen, M. U., Boeing, H., Meidtner, K., Palli, D., Masala, G., Bouatia-Naji, N., Saris, W. H. M., Feskens, E. J. M., Wareham, N. J., Sørensen, Thorkild I.A. & Loos, R. J. F., 2011, In: P L o S One. 6, 2, p. e17436

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Improved glycemic control induced by both metformin and repaglinide is associated with a reduction in blood levels of 3-deoxyglucosone in nonobese patients with type 2 diabetes

    Engelen, L., Lund, S. S., Ferreira, I., Tarnow, L., Parving, H., Gram, J., Winther, Kaj, Pedersen, Oluf Borbye, Teerlink, T., Barto, R., Stehouwer, C. D. A., Vaag, Allan & Schalkwijk, C. G., 2011, In: European Journal of Endocrinology. 164, 3, p. 371-9 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Changes in Glucose Homeostasis after Roux-en-Y Gastric Bypass Surgery for Obesity at Day Three, Two Months, and One Year after Surgery: Role of Gut Peptides

    Falkén, Y., Hellström, P. M., Holst, Jens Juul & Näslund, E., 2011, In: Journal of Clinical Endocrinology and Metabolism. 96, 7, p. 2227-35 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    A circadian rhythm orchestrated by histone deacetylase 3 controls hepatic lipid metabolism

    Feng, D., Liu, T., Sun, Z., Bugge, A. S., Mullican, S. E., Alenghat, T., Liu, X. S. & Lazar, M. A., 11 Mar 2011, In: Science (New York, N.Y.). 331, 6022, p. 1315-9 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Is socioeconomic status of the rearing environment causally related to obesity in the offspring?

    Fontaine, K. R., Robertson, H. T., Holst, C., Desmond, R., Stunkard, A. J., Sørensen, Thorkild I.A. & Allison, D. B., 2011, In: P L o S One. 6, 11, p. e27692

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Phosphorylation and Acetylation of Acyl-CoA Synthetase- I

    Frahm, J. L., Li, L. O., Grevengoed, Trisha Jean & Coleman, R. A., 22 Jul 2011, In: Journal of Proteomics & Bioinformatics. 4, 7, p. 129-137 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Genetic variation at CHRNA5-CHRNA3-CHRNB4 interacts with smoking status to influence body mass index

    Freathy, R. M., Kazeem, G. R., Morris, R. W., Johnson, P. C. D., Paternoster, L., Ebrahim, S., Hattersley, A. T., Hill, A., Hingorani, A. D., Holst, C., Jefferis, B. J., Kring, S. I. I., Mooser, V., Padmanabhan, S., Preisig, M., Ring, S. M., Sattar, N., Upton, M. N., Vollenweider, P., Waeber, G. & 8 others, Sørensen, Thorkild I.A., Frayling, T. M., Watt, G., Lawlor, D. A., Whincup, P. H., Tozzi, F., Davey Smith, G. & Munafò, M., 2011, In: International Journal of Epidemiology. 40, 6, p. 1617-28 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Intrafamilial Variability of Early-Onset Diabetes due to an INS Mutation

    Fredheim, S., Svensson, Jannet, Pørksen, S., Hansen, L., Hansen, Torben, Pedersen, Oluf Borbye, Mortensen, H. B., Barbetti, F. & Nielsen, L. B., 2011, In: Case Reports in Genetics. 2011, p. 258978

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    C-peptide increases Na,K-ATPase expression via PKC- and MAP kinase-dependent activation of transcription factor ZEB in human renal tubular cells

    Galuska, D., Pirkmajer, S., Barrès, Romain, Ekberg, K., Wahren, J. & Chibalin, A. V., 2011, In: P L o S One. 6, 12, p. e28294

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    In cirrhotic patients reduced muscle strength is unrelated to muscle capacity for ATP turnover suggesting a central limitation

    Gam, C. M. B., Nielsen, H. B., Secher, Niels H., Larsen, F. S., Ott, P. & Quistorff, B., May 2011, In: Clinical Physiology and Functional Imaging. 31, 3, p. 169-74 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Neuroethics and fMRI: Mapping a fledgling relationship

    Garnett, A., Whiteley, Louise, Piwowar, H., Rasmussen, E. & Illes, J., 22 Apr 2011, In: P L o S One. 6, 4, p. e18537

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    The cAMP/PKA Pathway Rapidly Activates SIRT1 to Promote Fatty Acid Oxidation Independently of Changes in NAD +

    Gerhart-Hines, Zach, Dominy, J. E., Blättler, S. M., Jedrychowski, M. P., Banks, A. S., Lim, J. H., Chim, H., Gygi, S. P. & Puigserver, P., 23 Dec 2011, In: Molecular Cell. 44, 6, p. 851-863 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Carriers of the TCF7L2 rs7903146 TT genotype have elevated levels of plasma glucose, serum proinsulin and plasma gastric inhibitory polypeptide (GIP) during a meal test

    Gjesing, A. P., Kjems, L. L., Vestmar, M. A., Grarup, N., Linneberg, Allan René, Deacon, Carolyn F., Holst, Jens Juul, Pedersen, Oluf Borbye & Hansen, Torben, 1 Jan 2011, In: Diabetologia. 54, 1, p. 103-10 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Studies of a genetic variant in HK1 in relation to quantitative metabolic traits and to the prevalence of type 2 diabetes

    Gjesing, A. P., Nielsen, A. A., Brandslund, I., Christensen, C., Sandbæk, A., Jørgensen, T., Witte, D., Bonnefond, A., Froguel, P., Hansen, Torben & Pedersen, Oluf Borbye, 1 Jan 2011, In: B M C Medical Genetics. 12, p. 99 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review