Novo Nordisk Foundation Center for Basic Metabolic Research

  1. 2015
  2. Published

    Browning of human adipocytes requires KLF11 and reprogramming of PPARγ superenhancers

    Loft, A., Forss, I., Siersbæk, M. S., Schmidt, S. F., Larsen, A. B., Madsen, J. G. S., Pisani, D. F., Nielsen, R., Aagaard, M. M., Mathison, A., Neville, M. J., Urrutia, R., Karpe, F., Amri, E. & Mandrup, S., 2015, In: Genes & Development. 29, p. 7-22 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Preoperative β-cell function in patients with type 2 diabetes is important for the outcome of Roux-en-Y gastric bypass surgery

    Lund, M. T., Hansen, M., Skaaby, Stinna, Dalby, S., Støckel, M., Floyd, A. K., Bech, K., Helge, Jørn Wulff, Holst, Jens Juul & Dela, Flemming, 13 Apr 2015, In: The Journal of Physiology. 593, 14, p. 3123-33 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Histone deacetylase 3 inhibition improves glycaemia and insulin secretion in obese diabetic rats

    Lundh, M., Galbo, T., Poulsen, Steen Seier & Mandrup-Poulsen, Thomas, Jul 2015, In: Diabetes, Obesity and Metabolism. 17, 7, p. 703-7 5 p.

    Research output: Contribution to journalLetterResearchpeer-review

  5. Published

    Asthma in patients with psoriasis

    Lønnberg, A. S., Skov, L., Skytthe, A., Kyvik, K. O., Pedersen, Oluf Borbye, Meteran, Howraman, Backer, Vibeke & Thomsen, Simon Francis, 2015, In: British Journal of Dermatology. p. 1660-1661

    Research output: Contribution to journalLetterResearchpeer-review

  6. Published

    Biotin starvation causes mitochondrial protein hyperacetylation and partial rescue by the SIRT3-like deacetylase Hst4p

    Madsen, C. T., Sylvestersen, K. B., Young, C., Buch-Larsen, Sara Charlotte, Poulsen, J. W., Andersen, M. A., Palmqvist, E. A., Hey-Mogensen, M., Jensen, P. B., Treebak, Jonas Thue, Lisby, Michael & Nielsen, Michael Lund, 2015, In: Nature Communications. 6, 12 p., 7726.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    iRNA-seq: computational method for genome-wide assessment of acute transcriptional regulation from total RNA-seq data

    Madsen, J. G. S., Schmidt, S. F., Larsen, B. D., Loft, A., Nielsen, R. & Mandrup, S., 31 Mar 2015, In: Nucleic Acids Research. 43, 6, p. 1-9 9 p., e40.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Identification and Functional Characterization of G6PC2 Coding Variants Influencing Glycemic Traits Define an Effector Transcript at the G6PC2-ABCB11 Locus

    Mahajan, A., Sim, X., Ng, H. J., Manning, A., Rivas, M. A., Highland, H. M., Locke, A. E., Grarup, N., Im, H. K., Cingolani, P., Flannick, J., Fontanillas, P., Fuchsberger, C., Gaulton, K. J., Teslovich, T. M., Rayner, N. W., Robertson, N. R., Beer, N. L., Rundle, J. K., Bork-Jensen, J. & 31 others, Ladenvall, C., Blancher, C., Buck, D., Buck, G., Burtt, N. P., Gabriel, S., Gjesing, A. M. P., Groves, C. J., Hollensted, M., Huyghe, J. R., Jackson, A. U., Jun, G., Justesen, Johanne Marie, Mangino, M., Murphy, J., Neville, M., Onofrio, R., Small, K. S., Stringham, H. M., Syvänen, A., Trakalo, J., Abecasis, G., Bell, G. I., Blangero, J., Cox, N. J., Duggirala, R., Linneberg, Allan René, Jørgensen, T., Hansen, Torben, Pedersen, Oluf Borbye & T2D-GENES consortium and GoT2D consortium, T. C. A. G. C., Jan 2015, In: P L o S Genetics. 11, 1, p. 1-25 25 p., e1004876.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    The 2-monoacylglycerol moiety of dietary fat appears to be responsible for the fat-induced release of GLP-1 in humans.

    Mandøe, M. J., Hansen, K. B., Hartmann, Bolette, Rehfeld, Jens Frederik, Holst, Jens Juul & Hansen, Harald S., 2015, In: The American Journal of Clinical Nutrition. 102, 3, p. 548-555 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Downregulation of 5-HT7 Serotonin Receptors by the Atypical Antipsychotics Clozapine and Olanzapine. Role of Motifs in the C-Terminal Domain and Interaction with GASP-1

    Manfra, O., Van Craenenbroeck, K., Skieterska, K., Frimurer, Thomas Michael, Schwartz, Thue W., Levy, F. O. & Andressen, K. W., Jul 2015, In: A C S Chemical Neuroscience. 6, 7, p. 1206–1218 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    RNA-Seq and Mass-Spectrometry-Based Lipidomics Reveal Extensive Changes of Glycerolipid Pathways in Brown Adipose Tissue in Response to Cold

    Marcher, A., Loft, A., Nielsen, R., Vihervaara, T., Madsen, J. G. S., Sysi-Aho, M., Ekroos, K. & Mandrup, S., 1 Dec 2015, In: Cell Reports. 13, 9, p. 2000-13 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    The gut microbiota modulates host amino acid and glutathione metabolism in mice

    Mardinoglu, A., Shoaie, S., Bergentall, M., Ghaffari, P., Zhang, C., Larsson, E., Bäckhed, G. F. & Nielsen, J., 2015, In: Molecular Systems Biology. 11, 10, p. 1-15 15 p., 834.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Effect of moderate- and high-intensity acute exercise on appetite in obese individuals

    Martins, C., Stensvold, D., Finlayson, G., Holst, Jens Juul, Wisloff, U., Kulseng, B., Morgan, L. & King, N. A., Jan 2015, In: Medicine and Science in Sports and Exercise. 47, 1, p. 40-8 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Immediate enhancement of first-phase insulin secretion and unchanged glucose effectiveness in patients with type 2 diabetes after Roux-en-Y gastric bypass

    Martinussen, C., Bojsen-Moller, K. N., Dirksen, C., Jacobsen, S. H., Jørgensen, N. B., Kristiansen, V. B., Holst, Jens Juul & Madsbad, Sten, 15 Mar 2015, In: American Journal of Physiology: Endocrinology and Metabolism. 308, 6, p. E535-44 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Central serotonergic neurons activate and recruit thermogenic brown and beige fat and regulate glucose and lipid homeostasis

    McGlashon, J. M., Gorecki, M. C., Kozlowski, A. E., Thirnbeck, C. K., Markan, K. R., Leslie, K. L., Kotas, M. E., Potthoff, M. J., Richerson, G. B. & Gillum, M. P., May 2015, In: Cell Metabolism. 21, 5, p. 692-705 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Effect of Antibiotics on Gut Microbiota, Gut Hormones and Glucose Metabolism

    Mikkelsen, K. H., Frost, M., Bahl, M. I., Licht, T. R., Jensen, U. S., Rosenberg, Jacob, Pedersen, Oluf Borbye, Hansen, Torben, Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, T. & Knop, Filip Krag, 12 Nov 2015, In: PLOS ONE. 10, 11, p. 1-14 e0142352.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Use of Antibiotics and Risk of Type 2 Diabetes: A Population-Based Case-Control Study

    Mikkelsen, K. H., Knop, Filip Krag, Frost, M., Hallas, J. & Pottegård, A., 2015, In: Journal of Clinical Endocrinology and Metabolism. 100, 10, p. 3633-40 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Uncovering the genetic history of the present-day greenlandic population

    Moltke, Ida, Fumagalli, M., Korneliussen, Thorfinn Sand, Crawford, J. E., Bjerregaard, P., Jørgensen, M. E., Grarup, N., Gulløv, H. C., Linneberg, Allan René, Pedersen, Oluf Borbye, Hansen, Torben, Nielsen, Rasmus & Albrechtsen, Anders, 2015, In: American Journal of Human Genetics. 96, 1, p. 54-69 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Prenatal exposure to systemic antibacterials and overweight and obesity in Danish schoolchildren: a prevalence study

    Mor, A., Antonsen, S., Kahlert, J., Holsteen, V., Jørgensen, S., Holm-Pedersen, J., Sørensen, H. T., Pedersen, Oluf Borbye & Ehrenstein, V., 2015, In: International journal of obesity (2005). 39, 10, p. 1450-1455 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Heavier smoking may lead to a relative increase in waist circumference: evidence for a causal relationship from a Mendelian randomisation meta-analysis. The CARTA consortium

    Morris, R. W., Taylor, A. E., Fluharty, M. E., Bjørngaard, J. H., Åsvold, B. O., Elvestad Gabrielsen, M., Campbell, A., Marioni, R., Kumari, M., Korhonen, T., Männistö, S., Marques-Vidal, P., Kaakinen, M., Cavadino, A., Postmus, I., Husemoen, L. L. N., Skaaby, T., Ahluwalia, T. V. S., Treur, J. L., Willemsen, G. & 42 others, Dale, C., Wannamethee, S. G., Lahti, J., Palotie, A., Räikkönen, K., McConnachie, A., Padmanabhan, S., Wong, A., Dalgård, C., Paternoster, L., Ben-Shlomo, Y., Tyrrell, J., Horwood, J., Fergusson, D. M., Kennedy, M. A., Nohr, E. A., Christiansen, L., Kyvik, K. O., Kuh, D., Watt, G., Eriksson, J. G., Whincup, P. H., Vink, J. M., Boomsma, D. I., Davey Smith, G., Lawlor, D., Linneberg, Allan René, Ford, I., Jukema, J. W., Power, C., Hyppönen, E., Jarvelin, M., Preisig, M., Borodulin, K., Kaprio, J., Kivimaki, M., Smith, B. H., Hayward, C., Romundstad, P. R., Sørensen, Thorkild I.A., Munafò, M. R. & Sattar, N., 2015, In: B M J Open. 5, 8, p. 1-10 10 p., e008808.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Novel combinatorial therapies involving leptin: Opportunities for mechanistic advances and therapeutic translation in human diseases

    Müller, T. D., Clemmensen, Christoffer, Finan, B., Dimarchi, R. D. & Tschöp, M. H., 1 Jan 2015, Leptin: Regulation and Clinical Applications. Springer, p. 267-279 13 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  22. Published

    Association study between CDH2 and Gilles de la Tourette syndrome in a Danish cohort

    Nazaryan, L., Bertelsen, B., Padmanabhuni, S. S., Debes, N. M., LuCamp, L., Have, C. T. & Tümer, Asuman Zeynep, 30 Aug 2015, In: Psychiatry Research. 228, 3, p. 974-5 2 p.

    Research output: Contribution to journalLetterResearchpeer-review

  23. Published

    Contribution of common non-synonymous variants in PCSK1 to body-mass index variation and risk of obesity: a systematic review and meta-analysis with evidence from up to 331,175 individuals

    Nead, K. T., Li, A., Wehner, M. R., Neupane, B., Gustafsson, S., Butterworth, A., Engert, J. C., Davis, A. D., Hegele, R. A., Miller, R., den Hoed, M., Khaw, K-T., Oskari Kilpeläinen, T., Wareham, N., Edwards, T. L., Hallmans, G., Varga, T. V., Kardia, S. L. R., Smith, J. A., Zhao, W. & 31 others, Faul, J. D., Weir, D., Mi, J., Xi, B., Canizales Quinteros, S., Cooper, C., Sayer, A. A., Jameson, K., Grøntved, A., Fornage, M., Sidney, S., Hanis, C. L., Highland, H. M., Häring, H., Heni, M., Lasky-Su, J., Weiss, S. T., Gerhard, G. S., Still, C., Melka, M. M., Pausova, Z., Paus, T., Grant, S. F. A., Hakonarson, H., Price, R. A., Wang, K., Scherag, A., Hebebrand, J., Hinney, A., Franks, P. W. & BioBank Japan, B. J., 17 Mar 2015, In: Human Molecular Genetics. 24, 2, p. 3582–3594 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Early child care and obesity at 12 months of age in the Danish National Birth Cohort

    Neelon, S. E. B., Andersen, C. S., Morgen, C. S., Kamper-Jørgensen, Mads, Oken, E., Gillman, M. W. & Sørensen, Thorkild I.A., 2015, In: International journal of obesity (2005). 39, p. 33-38 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    NKG2D-Dependent Activation of Dendritic Epidermal T cells in Contact Hypersensitivity

    Nielsen, M. M., Dyring-Andersen, Beatrice, Schmidt, J. D., Witherden, D., Lovato, P., Woetmann, Anders , Ødum, Niels, Poulsen, Steen Seier, Havran, W. L., Geisler, Carsten & Bonefeld, Charlotte Menne, May 2015, In: Journal of Investigative Dermatology. 135, 5, p. 1311-19 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Insulin resistance as a physiological defense against metabolic stress: implications for the management of subsets of type 2 diabetes

    Nolan, C. J., Ruderman, N. B., Kahn, S. E., Pedersen, Oluf Borbye & Prentki, M., Mar 2015, In: Diabetes. 64, 3, p. 673-86 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Response to Comments on Nolan et al. Insulin Resistance as a Physiological Defense Against Metabolic Stress: Implications for the Management of Subsets of Type 2 Diabetes. Diabetes 2015;64:673-686

    Nolan, C. J., Ruderman, N. B., Kahn, S. E., Pedersen, Oluf Borbye & Prentki, M., 2015, In: Diabetes. 64, 10, p. e38-9 2 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  28. Published

    Mutation-Guided Unbiased Modeling of the Fat Sensor GPR119 for High-Yield Agonist Screening.

    Norn, C., Pedersen, M. H., Engelstoft, M. S., Kim, S. H., Lehmann, J., Jones, R. M., Schwartz, Thue W. & Frimurer, Thomas Michael, 2015, In: Structure. 23, 12, p. 2377-2386 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Expression of the short chain fatty acid receptor GPR41/FFAR3 in autonomic and somatic sensory ganglia

    Nøhr, M. K., Egerod, Kristoffer Lihme, Christiansen, S. H., Gille, A., Offermanns, S., Schwartz, Thue W. & Møller, Morten, 2 Apr 2015, In: Neuroscience. 290, p. 126-37 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Diabetes mellitus and metabolic syndrome

    Ortega, E., Martín-Cordero, L., Garcia-Roves, P. M., Chicco, A. J., Gonzalez-Franquesa, A. & Marado, D., 1 Jan 2015, Biomarkers of Cardiometabolic Risk, Inflammation and Disease. Springer, p. 55-79 25 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  31. Published

    HOODS: finding context-specific neighborhoods of proteins, chemicals and diseases

    Palleja, A. & Jensen, Lars Juhl, 2015, In: PeerJ. 3, p. 1-10 10 p., e1057.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Comparative analyses of QTLs influencing obesity and metabolic phenotypes in pigs and humans

    Pant, S. D., Karlskov-Mortensen, Peter, Jacobsen, M. J., Cirera, Susanna, Kogelman, L., Bruun, Camilla Vibeke Sichlau, Mark, T., Jørgensen, Claus Bøttcher, Grarup, N., Appel, E. V. R., Galjatovic, E. A. A., Hansen, T., Pedersen, Oluf Borbye, Guerin, M., Huby, T., Lesnik, P., Meuwissen, T. H. E., Kadarmideen, H. & Fredholm, Merete, 8 Sep 2015, In: PLOS ONE. 10, 9, 22 p., e0137356.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis

    Paternoster, L., Standl, M., Waage, J., Baurecht, H., Hotze, M., Strachan, D. P., Curtin, J. A., Bønnelykke, K., Tian, C., Takahashi, A., Esparza-Gordillo, J., Alves, A. C., Thyssen, J. P., den Dekker, H. T., Ferreira, M. A., Altmaier, E., Sleiman, P. M. A., Xiao, F. L., Gonzalez, J. R., Marenholz, I. & 31 others, Kalb, B., Pino-Yanes, M., Xu, C., Carstensen, L., Groen-Blokhuis, M. M., Venturini, C., Pennell, C. E., Barton, S. J., Levin, A. M., Curjuric, I., Bustamante, M., Kreiner-Møller, E., Lockett, G. A., Bacelis, J., Bunyavanich, S., Myers, R. A., Matanovic, A., Kumar, A., Tung, J. Y., Hirota, T., Kubo, M., McArdle, W. L., Henderson, A. J., Kemp, J. P., Zheng, J., Smith, G. D., Grarup, N., Bisgaard, H., Melbye, M., Linneberg, Allan René & Australian Asthma Genetics Consortium (AAGC), A. A. G. C. (., Dec 2015, In: Nature Genetics. 47, 12, p. 1449-56 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    GPR40 (FFAR1) – Combined Gs and Gq signaling in vitro is associated with robust incretin secretagogue action ex vivo and in vivo

    Pedersen, M. H., Bentsen, M. A., Husted, Anna Sofie, Ekberg, J. P., Wright, M. J., Di Salvo, J., Weinglass, A. B., Engelstoft, M. S., Madsen, A. N., Lückmann, Michael, Miller, M. W., Trujillo, M. E., Frimurer, Thomas Michael, Holst, Birgitte, Howard, A. D. & Schwartz, Thue W., Jan 2015, In: Molecular Metabolism. 4, 1, p. 3-14 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Plasma proteomics classifiers improve risk prediction for renal disease in patients with hypertension or type 2 diabetes

    Pena, M. J., Jankowski, J., Heinze, G., Kohl, M., Heinzel, A., Bakker, S. J. L., Gansevoort, R. T., Rossing, Peter, de Zeeuw, D., Heerspink, H. J. L. & Jankowski, V., Oct 2015, In: Journal of Hypertension. 33, 10, p. 2123-32 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Prognostic clinical and molecular biomarkers of renal disease in type 2 diabetes

    Pena, M. J., de Zeeuw, D., Mischak, H., Jankowski, J., Oberbauer, R., Woloszczuk, W., Benner, J., Dallmann, G., Mayer, B., Mayer, G., Rossing, Peter & Lambers Heerspink, H. J., Aug 2015, In: Nephrology, Dialysis, Transplantation. 30, Suppl 4, p. iv86-95

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Hepatic NAD salvage pathway is enhanced in mice on a high-fat diet

    Penke, M., Larsen, P. S., Schuster, S., Dall, M., Jensen, Benjamin Anderschou Holbech, Gorski, T., Meusel, A., Richter, S., Vienberg, S. G., Treebak, Jonas Thue, Kiess, W. & Garten, A., 2015, In: Molecular and Cellular Endocrinology. 412, p. 65-72 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Cuff inflations do not affect night-time blood pressure: comparison of 24 h ambulatory blood pressure measured by a cuff and a tonometric device in type 2 diabetes

    Petersen, E. H., Theilade, S., Hansen, T. W., Lindhardt, M. K. & Rossing, Peter, Dec 2015, In: Blood Pressure Monitoring. 20, 6, p. 369-72 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Severe hypoglycaemia during treatment with sulphonylureas in patients with type 2 diabetes in the Capital Region of Denmark

    Pilemann-Lyberg, S., Thorsteinsson, B., Snorgaard, O., Zander, M., drb459, drb459 & Røder, M. E., 2015, In: Diabetes Research and Clinical Practice. 110, 2, p. 202-7 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Inflammatory and metabolic alterations of Kager's fat pad in chronic achilles tendinopathy

    Pingel, Jessica, Petersen, M. C. H., Fredberg, U., Kjær, S. G., Quistorff, B., Langberg, Henning & Hansen, Jacob B., 2015, In: P L o S One. 10, 5, 13 p., e0127811.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    The role of efferent cholinergic transmission for the insulinotropic and glucagonostatic effects of GLP-1

    Plamboeck, A., Veedfald, Simon, Deacon, Carolyn F., Hartmann, Bolette, Vilsbøll, T., Knop, Filip Krag & Holst, Jens Juul, Sep 2015, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 309, 5, p. R544-51 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    DISEASES: Text mining and data integration of disease-gene associations

    Pletscher-Frankild, S., Pallejà, A., Tsafou, K., Binder, J. X. & Jensen, Lars Juhl, Mar 2015, In: Methods. 74, p. 83-9 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Circulating miR-192 and miR-193b are markers of prediabetes and are modulated by an exercise intervention

    Párrizas, M., Brugnara, L., Esteban, Y., González-Franquesa, A., Canivell, S., Murillo, S., Gordillo-Bastidas, E., Cussó, R., Cadefau, J. A., García-Roves, P. M., Servitja, J. & Novials, A., Mar 2015, In: The Journal of clinical endocrinology and metabolism. 100, 3, p. E407-15

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Dietary intake, FTO genetic variants and adiposity: a combined analysis of over 16,000 children and adolescents

    Qi, Q., Downer, M. K., Oskari Kilpeläinen, T., Taal, H. R., Barton, S. J., Ntalla, I., Standl, M., Boraska, V., Huikari, V., Kiefte-de Jong, J. C., Körner, A., Lakka, T. A., Liu, G., Magnusson, J., Okuda, M., Raitakari, O., Richmond, R., Scott, R. A., Bailey, M. E. S., Scheuermann, K. & 22 others, Holloway, J. W., Inskip, H., Isasi, C. R., Mossavar-Rahmani, Y., Jaddoe, V. W. V., Laitinen, J., Lindi, V., Melén, E., Pitsiladis, Y., Pitkänen, N., Snieder, H., Heinrich, J., Timpson, N. J., Wang, T., Yuji, H., Zeggini, E., Dedoussis, G. V., Kaplan, R. C., Wylie-Rosett, J., Loos, R. J. F., Hu, F. B. & Qi, L., Jul 2015, In: Diabetes. 64, 7, p. 2467-76 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Impaired oxidative capacity due to decreased CPT1b levels as a contributing factor to fat accumulation in obesity

    Ratner, C., Madsen, A. N., Kristensen, L. V., Skov, Louise Julie, Pedersen, K. S., Mortensen, Ole Hartvig, Knudsen, Gitte Moos, Raun, K. & Holst, Birgitte, 8 Apr 2015, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 308, 11, p. R973-R982 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Dual-hormone treatment with insulin and glucagon in patients with type 1 diabetes

    Reiband, H. K., Schmidt, S., Ranjan, A., Holst, Jens Juul, Madsbad, Sten & Nørgaard, Kirsten, 2015, In: Diabetes - Metabolism: Research and Reviews (Print Edition). 31, 7, p. 672-9 8 p.

    Research output: Contribution to journalReviewResearchpeer-review

  47. Published

    Effect of Roux-en-Y gastric bypass on the distribution and hormone expression of small-intestinal enteroendocrine cells in obese patients with type 2 diabetes

    Rhee, N. A., Wahlgren, C. D., Pedersen, J., Mortensen, B., Langholz, E., Wandall, E. P., Friis, S. U., Vilmann, Peter, Paulsen, S. J., Kristiansen, V. B., Jelsing, J., Dalbøge, L. S., Poulsen, Steen Seier, Holst, Jens Juul, Vilsbøll, T. & Knop, Filip Krag, 2015, In: Diabetologia. 58, 10, p. 2254-2258 5 p.

    Research output: Contribution to journalLetterResearchpeer-review

  48. Published

    Exploring possible epigenetic mediation of early-life environmental exposures on adiposity and obesity development

    Richmond, R. C., Timpson, N. J. & Sørensen, Thorkild I.A., Aug 2015, In: International Journal of Epidemiology. 44, 4, p. 1191-8 8 p.

    Research output: Contribution to journalReviewResearchpeer-review

  49. Published

    Population genetic differentiation of height and body mass index across Europe

    Robinson, M. R., Hemani, G., Medina-Gomez, C., Mezzavilla, M., Esko, T., Shakhbazov, K., Powell, J. E., Vinkhuyzen, A., Berndt, S. I., Gustafsson, S., Justice, A. E., Kahali, B., Locke, A. E., Pers, T. H., Vedantam, S., Wood, A. R., van Rheenen, W., Andreassen, O. A., Gasparini, P., Metspalu, A. & 23 others, Berg, L. H. V. D., Veldink, J. H., Rivadeneira, F., Werge, Thomas, Abecasis, G. R., Boomsma, D. I., Chasman, D. I., de Geus, E. J. C., Frayling, T. M., Hirschhorn, J. N., Hottenga, J. J., Ingelsson, E., Loos, R. J. F., Magnusson, P. K. E., Martin, N. G., Montgomery, G. W., North, K. E., Pedersen, N. L., Spector, T. D., Speliotes, E. K., Goddard, M. E., Yang, J. & Visscher, P. M., Nov 2015, In: Nature Genetics. 47, 11, p. 1357-62, 2 unpag. Methods 8 p.

    Research output: Contribution to journalLetterResearchpeer-review

  50. Published

    Peptidomics combined with cDNA library unravel the diversity of centipede venom

    Rong, M., Yang, S., Wen, B., Mo, G., Kang, D., Liu, J., Lin, Z., Jiang, W., Li, B., Du, C., Yang, S., Jiang, H., Feng, Q., Xu, X., Wang, J. & Lai, R., 30 Jan 2015, In: Journal of Proteomics. 114, 1, p. 28-37 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Inability to match energy intake with energy expenditure at sustained near-maximal rates of energy expenditure in older men during a 14-d cycling expedition

    Rosenkilde Larsen, M., Morville, T., Riis Andersen, P., Kjær, K., Rasmusen, H., Holst, Jens Juul, Dela, Flemming, Westerterp, K., Sjödin, Anders Mikael & Helge, Jørn Wulff, 2015, In: American Journal of Clinical Nutrition. 102, 6, p. 1398-1405 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Specific inhibition of bile acid transport alters plasma lipids and GLP-1

    Rudling, M., Camilleri, M., Graffner, H., Holst, Jens Juul & Rikner, L., 2015, In: B M C Cardiovascular Disorders. 15, p. 1-8 8 p., 75.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Impact of age, BMI and HbA1c levels on the genome-wide DNA methylation and mRNA expression patterns in human adipose tissue and identification of epigenetic biomarkers in blood

    Rönn, T., Volkov, P., Gillberg, L., Kokosar, M., Perfilyev, A., Jacobsen, A. L., Jørgensen, S. W., Brøns, C., Jansson, P., Eriksson, K., Pedersen, Oluf Borbye, Hansen, Torben, Groop, L., Stener-Victorin, E., Vaag, Allan, Nilsson, E. & Ling, C., 1 Jul 2015, In: Human Molecular Genetics. 24, 13, p. 3792-813 22 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    L-glutamine and whole protein restore first-phase insulin response and increase glucagon-like Peptide-1 in type 2 diabetes patients

    Samocha-Bonet, D., Chisholm, D. J., Holst, Jens Juul & Greenfield, J. R., 2015, In: Nutrients. 7, 4, p. 2101-8 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    Genome-wide association studies of human adiposity: Zooming in on synapses.

    Sandholt, C. H., Grarup, N., Pedersen, Oluf Borbye & Hansen, Torben, 2015, In: Molecular and Cellular Endocrinology. 418, Part 2, p. 90-100 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    Obesity Beige adipocytes-will they beat obesity?.

    Sandholt, C. H. & Pedersen, Oluf Borbye, 2015, In: Nature Reviews Endocrinology. 11, 12, p. 694-696 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    About this book

    Sandøe, Peter, Jensen, Karsten Klint & Whiteley, Louise, Sep 2015, RCR – A Danish textbook for courses in Responsible Conduct of Research. Jensen, K. K., Whiteley, L. & Sandøe, P. (eds.). 1. ed. Frederiksberg: Department of Food and Resource Economics, University of Copenhagen, p. 1-4 4 p.

    Research output: Chapter in Book/Report/Conference proceedingPreface/postscriptEducation

  58. Published

    Optimisation of in silico derived 2-aminobenzimidazole hits as unprecedented selective kappa opioid receptor agonists

    Sasmal, P. K., Krishna, C. V., Sudheerkumar Adabala, S., Rawoof, K. A., Thadi, A., Sukumar, K. P., Cheera, S., Abbineni, C., Rao, K. V. L. N., Prasanthi, A., Nijhawan, K., Jaleel, M., Ramachandran Iyer, L., Chaitanya, T. K., Tiwari, N. K., Krishna, N. L., Potluri, V., Khanna, I., Frimurer, T. M., Lückmann, M. & 3 others, Rist, Ø., Elster, L. & Högberg, T., 15 Feb 2015, In: Bioorganic & Medicinal Chemistry Letters. 25, 4, p. 887-92 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    Smoking and diabetes risk: building a causal case with clinical implications

    Sattar, N., Sørensen, Thorkild I.A., Taylor, A. E., Morris, R. & Munafò, M. R., Dec 2015, In: The Lancet Diabetes & Endocrinology. 3, 12, p. 918-20 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    No association of maternal gestational weight gain with offspring blood pressure and hypertension at age 18 years in male sibling-pairs: a prospective register-based cohort study

    Scheers Andersson, E., Tynelius, P., Nohr, E. A., Sørensen, Thorkild I.A. & Rasmussen, F., 20 Mar 2015, In: PLOS ONE. 10, 3, p. 1-12 12 p., e0121202.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published

    The renal protective effect of angiotensin receptor blockers depends on intra-individual response variation in multiple risk markers

    Schievink, B., de Zeeuw, D., Parving, H., Rossing, Peter & Lambers Heerspink, H. J., Oct 2015, In: British Journal of Clinical Pharmacology. 80, 4, p. 678-86 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. Published

    Acute TNF-induced repression of cell identity genes is mediated by NFκB-directed redistribution of cofactors from super-enhancers

    Schmidt, S. F., Larsen, B. D., Loft, A., Nielsen, R., Madsen, J. G. S. & Mandrup, S., Sep 2015, In: Genome Research. 25, 9, p. 1281-94 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    Effects of sitagliptin on counterregulatory and incretin hormones during acute hypoglycaemia in patients with type 1 diabetes: a randomized double blind placebo-controlled cross-over study

    Schopman, J. E., Hoekstra, J. B. L., Frier, B. M., Ackermans, M. T., de Sonnaville, J. J. J., Stades, A. M., Zwertbroek, R., Hartmann, Bolette, Holst, Jens Juul, Knop, Filip Krag & Holleman, F., Jun 2015, In: Diabetes, Obesity and Metabolism. 17, 6, p. 546-53 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. Published

    Vitamin D-rich marine Inuit diet and markers of inflammation – a population-based survey in Greenland

    Schæbel, L. K., Bonefeld-Jørgensen, E. C., Laurberg, P., drb459, drb459 & Andersen, S., Oct 2015, In: Journal of Nutritional Science. 4, p. 1-8 8 p., e40.

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. Published

    Hypoglycemia-associated changes in the electroencephalogram in patients with type 1 diabetes and normal hypoglycemia awareness or unawareness

    Sejling, A., Kjær, T. W., Pedersen-Bjergaard, Ulrik, Diemar, S. S., Frandsen, C. S. S., Hilsted, L., Faber, Jens, Holst, Jens Juul, Tarnow, L., Nielsen, M. N., Remvig, L. S., Thorsteinsson, B. & Juhl, C. B., May 2015, In: Diabetes. 64, 5, p. 1760-9 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  66. Published

    Infrared thermographic assessment of changes in skin temperature during hypoglycaemia in patients with type 1 diabetes

    Sejling, A., Lange, Kai, Frandsen, C. S., Diemar, S. S., Tarnow, L., Faber, Jens, Holst, Jens Juul, Hartmann, Bolette, Hilsted, Linda, Kjaer, T. W., Juhl, C. B., Thorsteinsson, B. & Pedersen-Bjergaard, Ulrik, 2015, In: Diabetologia. 58, p. 1898–1906 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  67. Published

    Early gradual feeding with bovine colostrum improves gut function and NEC resistance relative to infant formula in preterm pigs

    Shen, René Liang, Thymann, Thomas, Østergaard, M. V., Støy, A. C. F., Krych, Lukasz, Nielsen, Dennis Sandris, Lauridsen, C., Hartmann, Bolette, Holst, Jens Juul, Burrin, D. G. & Sangild, Per Torp, 2015, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 309, 5, p. G310-G323 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    Quantifying Diet-Induced Metabolic Changes of the Human Gut Microbiome

    Shoaie, S., Ghaffari, P., Kovatcheva-Datchary, P., Mardinoglu, A., Sen, P., Pujos-Guillot, E., de Wouters, T., Juste, C., Rizkalla, S., Chilloux, J., Hoyles, L., Nicholson, J. K., Dore, J., Dumas, M. E., Clement, K., Bäckhed, G. F., Nielsen, J. & MICRO-Obes Consortium, M. C., 4 Aug 2015, In: Cell Metabolism. 22, 2, p. 320-31 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. Published

    The CODATwins Project: The Cohort Description of Collaborative Project of Development of Anthropometrical Measures in Twins to Study Macro-Environmental Variation in Genetic and Environmental Effects on Anthropometric Traits

    Silventoinen, K., Jelenkovic, A., Sund, R., Honda, C., Aaltonen, S., Yokoyama, Y., Tarnoki, A. D., Tarnoki, D. L., Ning, F., Ji, F., Pang, Z., Ordoñana, J. R., Sánchez-Romera, J. F., Colodro-Conde, L., Burt, S. A., Klump, K. L., Medland, S. E., Montgomery, G. W., Kandler, C., McAdams, T. A. & 106 others, Eley, T. C., Gregory, A. M., Saudino, K. J., Dubois, L., Boivin, M., Haworth, C. M. A., Plomin, R., Öncel, S. Y., Aliev, F., Stazi, M. A., Fagnani, C., D'Ippolito, C., Craig, J. M., Saffery, R., Siribaddana, S. H., Hotopf, M., Sumathipala, A., Spector, T., Mangino, M., Lachance, G., Gatz, M., Butler, D. A., Bayasgalan, G., Narandalai, D., Freitas, D. L., Maia, J. A., Harden, K. P., Tucker-Drob, E. M., Christensen, K., Skytthe, A., Kyvik, K. O., Hong, C., Chong, Y., Derom, C. A., Vlietinck, R. F., Loos, R. J. F., Cozen, W., Hwang, A. E., Mack, T. M., He, M., Ding, X., Chang, B., Silberg, J. L., Eaves, L. J., Maes, H. H., Cutler, T. L., Hopper, J. L., Aujard, K., Magnusson, P. K. E., Pedersen, N. L., Aslan, A. K. D., Song, Y., Yang, S., Lee, K., Baker, L. A., Tuvblad, C., Bjerregaard-Andersen, M., Beck-Nielsen, H., Sodemann, M., Heikkilä, K., Tan, Q., Zhang, D., Swan, G. E., Krasnow, R., Jang, K. L., Knafo-Noam, A., Mankuta, D., Abramson, L., Lichtenstein, P., Krueger, R. F., McGue, M., Pahlen, S., Tynelius, P., Duncan, G. E., Buchwald, D., Corley, R. P., Huibregtse, B. M., Nelson, T. L., Whitfield, K. E., Franz, C. E., Kremen, W. S., Lyons, M. J., Ooki, S., Brandt, I., Nilsen, T. S., Inui, F., Watanabe, M., Bartels, M., van Beijsterveldt, T. C. E. M., Wardle, J., Llewellyn, C. H., Fisher, A., Rebato, E., Martin, N. G., Iwatani, Y., Hayakawa, K., Rasmussen, F., Sung, J., Harris, J. R., Willemsen, G., Busjahn, A., Goldberg, J. H., Boomsma, D. I., Hur, Y., Sørensen, Thorkild I.A. & Kaprio, J., Aug 2015, In: Twin Research and Human Genetics. 18, 4, p. 348-60 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. Published

    Intake of Lactobacillus reuteri Improves Incretin and Insulin Secretion in Glucose-Tolerant Humans: A Proof of Concept

    Simon, M., Strassburger, K., Nowotny, B., Kolb, H., Nowotny, P., Burkart, V., Zivehe, F., Hwang, J., Stehle, P., Pacini, G., Hartmann, Bolette, Holst, Jens Juul, MacKenzie, C., Bindels, L. B., Martinez, I., Walter, J., Henrich, B., Schloot, N. C. & Roden, M., 2015, In: Diabetes Care. 38, 10, p. 1827-34 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  71. Published

    Differential effects of glucagon-like peptide-1 on microvascular recruitment and glucose metabolism in short- and long-term Insulin resistance

    Sjøberg, K. A., Rattigan, S., Jeppesen, J. F., Lundsgaard, Anne-Marie, Holst, Jens Juul & Kiens, Bente, 2015, In: Journal of Physiology. 593, 9, p. 2185-2198 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  72. Published

    No changes in serum tryptase after bariatric surgery

    Skaaby, T., drb459, drb459, Thomsen, S., Knudsen, A. L., Jørgensen, Niklas Rye & Linneberg, Allan René, 2015, In: Annals of Epidemiology. 25, 10, p. 800-1 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  73. Published

    The gut microbiota engages different signaling pathways to induce Duox2 expression in the ileum and colon epithelium

    Sommer, F. & Bäckhed, G. F., Mar 2015, In: Mucosal Immunology. 8, 2, p. 372-9 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. Published

    Site-specific programming of the host epithelial transcriptome by the gut microbiota

    Sommer, F., Nookaew, I., Sommer, N., Fogelstrand, P. & Bäckhed, G. F., 2015, In: Genome Biology (Online Edition). 16, p. 1-15 15 p., 62.

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. Published

    Comment on Xu et al. Effects of Metformin on Metabolite Profiles and LDL Cholesterol in Patients With Type 2 Diabetes

    Sonne, David Peick & Knop, Filip Krag, Dec 2015, In: Diabetes Care. 38, 12, p. e215 1 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  76. Published

    Pancreatic Amylase and Lipase Plasma Concentrations Are Unaffected by Increments in Endogenous GLP-1 Levels Following Liquid Meal Tests

    Sonne, David Peick, Vilsbøll, T. & Knop, Filip Krag, 2015, In: Diabetes Care. 38, 5, p. e71-2 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. Published

    Atmospheric Smell: hospital-based and museum-staged

    Stenslund, A., 2015, SL Grafik. 216 p.

    Research output: Book/ReportPh.D. thesis

  78. Published

    Reduced CD300LG mRNA tissue expression, increased intramyocellular lipid content and impaired glucose metabolism in healthy male carriers of Arg82Cys in CD300LG: a novel genometabolic cross-link between CD300LG and common metabolic phenotypes

    Støy, J., Kampmann, U., Mengel, A., Magnusson, N. E., Jessen, N., Grarup, N., Rungby, Jørgen, Stødkilde-Jørgensen, H., Brandslund, I., Christensen, C., Hansen, Torben, Pedersen, Oluf Borbye & Møller, N., 2015, In: BMJ open diabetes research & care. 3, 1, p. 1-12 12 p., e000095.

    Research output: Contribution to journalJournal articleResearchpeer-review

  79. Published

    Updates in weight loss surgery and gastrointestinal peptides

    Svane, M. S., Bojsen-Møller, K. N., Madsbad, Sten & Holst, Jens Juul, Feb 2015, In: Current Opinion in Endocrinology, Diabetes and Obesity. 22, 1, p. 21-8 8 p.

    Research output: Contribution to journalReviewResearchpeer-review

  80. Published

    An Analysis of Cosecretion and Coexpression of Gut Hormones From Male Rat Proximal and Distal Small Intestine

    Svendsen, B., Pedersen, Jens, Albrechtsen, Nicolai Jacob Wewer, Hartmann, Bolette, Toräng, S., Rehfeld, Jens Frederik, Poulsen, Steen Seier & Holst, Jens Juul, Mar 2015, In: Endocrinology. 156, 3, p. 847-857 11 p., en20141710.

    Research output: Contribution to journalJournal articleResearchpeer-review

  81. Published

    Childhood maltreatment and obesity

    Sørensen, Thorkild I.A., Aug 2015, In: Obesity. 23, 8, p. 1528 1 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  82. Published

    Endogenous GLP-1 mediates postprandial reductions in activation in central reward and satiety areas in patients with type 2 diabetes

    Ten Kulve, J. S., Veltman, D. J., van Bloemendaal, L., Barkhof, F., Deacon, Carolyn F., Holst, Jens Juul, Konrad, R. J., Sloan, J. H., Drent, M. L., Diamant, M. & IJzerman, R. G., Dec 2015, In: Diabetologia. 58, 12, p. 2688-98 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  83. Published

    Associations of the Inflammatory Marker YKL-40 with Measures of Obesity and Dyslipidaemia in Individuals at High Risk of Type 2 Diabetes

    Thomsen, S. B., Gjesing, A. M. P., Rathcke, C. N., Ekstrøm, Claus Thorn, Eiberg, Hans Rudolf Lytchoff, Hansen, T., Pedersen, Oluf Borbye & drb459, drb459, 21 Jul 2015, In: PLOS ONE. 10, 7, p. 1-10 10 p., e0133672.

    Research output: Contribution to journalJournal articleResearchpeer-review

  84. Published

    Assessment of body composition by dual-energy X-ray absorptiometry, bioimpedance analysis and anthropometrics in children: the Physical Activity and Nutrition in Children study

    Tompuri, T. T., Lakka, T. A., Hakulinen, M., Lindi, V., Laaksonen, D. E., Kilpeläinen, Tuomas O., Jääskeläinen, J., Lakka, H. & Laitinen, T., 2015, In: Clinical Physiology and Functional Imaging. 35, 1, p. 21-33 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  85. Published

    The anorexic hormone Peptide YY3-36 is rapidly metabolized to inactive Peptide YY3-34 in vivo.

    Toräng, S., Veedfald, Simon, Rosenkilde, Mette, Hartmann, Bolette & Holst, Jens Juul, 20 Jul 2015, In: Physiological Reports. 3, 7, p. 1-8 8 p., e12455.

    Research output: Contribution to journalJournal articleResearchpeer-review

  86. Published

    NNMT: A Bad Actor in Fat Makes Good in Liver

    Trammell, Sam & Brenner, C., 4 Aug 2015, In: Cell Metabolism. 22, 2, p. 200-201 2 p.

    Research output: Contribution to journalEditorialResearchpeer-review

  87. Published

    Roux-en-Y Gastric Bypass and Vertical Banded Gastroplasty Induce Long-Term Changes on the Human Gut Microbiome Contributing to Fat Mass Regulation

    Tremaroli, V., Karlsson, F., Werling, M., Ståhlman, M., Kovatcheva-Datchary, P., Olbers, T., Fändriks, L., le Roux, C. W., Nielsen, J. & Bäckhed, G. F., 4 Aug 2015, In: Cell Metabolism. 22, 2, p. 228-38 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  88. Published

    Biased Gs Versus Gq Proteins and β-Arrestin Signaling in the NK1 Receptor Determined by Interactions in the Water Hydrogen Bond Network

    Valentin-Hansen, L., Frimurer, Thomas Michael, Mokrosinski, J., Holliday, N. D. & Schwartz, Thue W., 2 Oct 2015, In: The Journal of Biological Chemistry. 290, 40, p. 24495-508 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  89. Published

    Genome of the Netherlands population-specific imputations identify an ABCA6 variant associated with cholesterol levels

    Van Leeuwen, E. M., Karssen, L. C., Deelen, J., Isaacs, A., Medina-Gomez, C., Mbarek, H., Kanterakis, A., Trompet, S., Postmus, I., Verweij, N., Van Enckevort, D. J., Huffman, J. E., White, C. C., Feitosa, M. F., Bartz, T. M., Manichaikul, A., Joshi, P. K., Peloso, G. M., Deelen, P., Van Dijk, F. & 105 others, Willemsen, G., De Geus, E. J., Milaneschi, Y., Penninx, B. W. J. H., Francioli, L. C., Menelaou, A., Pulit, S. L., Rivadeneira, F., Hofman, A., Oostra, B. A., Franco, O. H., Leach, I. M., Beekman, M., De Craen, A. J. M., Uh, H. W., Trochet, H., Hocking, L. J., Porteous, D. J., Sattar, N., Packard, C. J., Buckley, B. M., Brody, J. A., Bis, J. C., Rotter, J. I., Mychaleckyj, J. C., Campbell, H., Duan, Q., Lange, L. A., Wilson, J. F., Hayward, C., Polasek, O., Vitart, V., Rudan, I., Wright, A. F., Rich, S. S., Psaty, B. M., Borecki, I. B., Kearney, P. M., Stott, D. J., Cupples, L. A., Jukema, J. W., Van Der Harst, P., Sijbrands, E. J., Hottenga, J. J., Uitterlinden, A. G., Swertz, M. A., Van Ommen, G. J. B., De Bakker, P. I. W., Eline Slagboom, P., Boomsma, D. I., Wijmenga, C., Van Duijn, C. M., Neerincx, P. B. T., Elbers, C. C., Palamara, P. F., Peer, I., Abdellaoui, A., Kloosterman, W. P., Van Oven, M., Vermaat, M., Li, M., Laros, J. F. J., Stoneking, M., De Knijff, P., Kayser, M., Veldink, J. H., Van Den Berg, L. H., Byelas, H., Den Dunnen, J. T., Dijkstra, M., Amin, N., Van Der Velde, K. J., Van Setten, J., Kattenberg, M., Van Schaik, B. D. C., Bot, J., Nijman, I. J., Mei, H., Koval, V., Ye, K., Lameijer, E. W., Moed, M. H., Hehir-Kwa, J. Y., Handsaker, R. E., Sunyaev, S. R., Sohail, M., Hormozdiari, F., Marschall, T., Schönhuth, A., Guryev, V., Suchiman, H. E. D., Wolffenbuttel, B. H., Platteel, M., Pitts, S. J., Potluri, S., Cox, D. R., Li, Q., Li, Y., Du, Y., Chen, R., Cao, H., Li, N., Cao, S., Wang, J. & Bovenberg, J. A., 2015, In: Nature Communications. 6, 6 p., 6065.

    Research output: Contribution to journalJournal articleResearchpeer-review

  90. Published

    Pancreatic polypeptide responses to isoglycemic oral and intravenous glucose in humans with and without intact vagal innervation

    Veedfald, Simon, Plamboeck, A., Hartmann, Bolette, Svendsen, Lars Bo, Vilsbøll, T., Knop, Filip Krag & Holst, Jens Juul, Sep 2015, In: Peptides. 71, p. 229-31 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  91. Published

    Proteome- and transcriptome-driven reconstruction of the human myocyte metabolic network and its use for identification of markers for diabetes

    Väremo, L., Schéele, Camilla Charlotte Nielsen, Broholm, C., Mardinoglu, A., Kampf, C., Asplund, A., Nookaew, I., Uhlén, M., Pedersen, Bente Klarlund & Nielsen, J., 2015, In: Cell Reports. 11, 6, p. 921-33 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  92. Published

    Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility

    Wessel, J., Chu, A. Y., Willems, S. M., Wang, S., Yaghootkar, H., Brody, J. A., Dauriz, M., Hivert, M-F., Raghavan, S., Lipovich, L., Hidalgo, B., Fox, K., Huffman, J. E., An, P., Lu, Y., Rasmussen-Torvik, L. J., Grarup, N., Ehm, M. G., Li, L., Baldridge, A. S. & 31 others, Stančáková, A., Abrol, R., Besse, C., Boland, A., Bork-Jensen, J., Fornage, M., Freitag, D. F., Garcia, M. E., Guo, X., Hara, K., Isaacs, A., Jakobsdottir, J., Lange, L. A., Layton, J. C., Li, M., Hua Zhao, J., Meidtner, K., Morrison, A. C., Nalls, M. A., Peters, M. J., Sabater-Lleal, M., Schurmann, C., Silveira, A., Smith, A. V., Southam, L., Allin, K. H., Jørgensen, T., Linneberg, Allan René, Hansen, Torben, Pedersen, Oluf Borbye & EPIC-InterAct Consortium, E. C., 29 Jan 2015, In: Nature Communications. 6, p. 5897

    Research output: Contribution to journalJournal articleResearchpeer-review

  93. Published

    Public Science Communication

    Whiteley, Louise, 2015, RCR – A Danish textbook for courses in Responsible Conduct of Research. Jensen, K. K., Whiteley, L. & Sandøe, P. (eds.). Frederiksberg, p. 90-107

    Research output: Chapter in Book/Report/Conference proceedingBook chapterEducation

  94. Published

    The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

    Winkler, T. W., Justice, A. E., Graff, M., Barata, L., Feitosa, M. F., Chu, S., Czajkowski, J., Esko, T., Fall, T., Kilpeläinen, T. O., Lu, Y., Mägi, R., Mihailov, E., Pers, T. H., Rüeger, S., Teumer, A., Ehret, G. B., Ferreira, T., Heard-Costa, N. L., Karjalainen, J. & 31 others, Lagou, V., Mahajan, A., Neinast, M. D., Prokopenko, I., Simino, J., Teslovich, T. M., Jansen, R., Westra, H., White, C. C., Absher, D., Ahluwalia, Tarun Veer Singh, Ahmad, S., Albrecht, E., Alves, A. C., Bragg-Gresham, J. L., de Craen, A. J. M., Bis, J. C., Bonnefond, A., Boucher, G., Banasik, Karina, Grarup, N., Hansen, Torben, Jørgensen, T., Krarup, N. T., Linneberg, Allan René, Ribel-Madsen, R., Sparsø, T. H., Melbye, M., Pedersen, Oluf Borbye, Sørensen, Thorkild I.A. & CHARGE Consortium, C. C., 1 Oct 2015, In: P L o S Genetics. 11, 10, p. 1-42 42 p., e1005378.

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. Published

    Synaptotagmin-7 phosphorylation mediates GLP-1-dependent potentiation of insulin secretion from β-cells

    Wu, B., Wei, S., Petersen, N., Ali, Y., Wang, X., Bacaj, T., Rorsman, P., Hong, W., Südhof, T. C. & Han, W., 11 Aug 2015, In: National Academy of Sciences. Proceedings. 112, 32, p. 9996-10001 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  96. Published

    Linking Microbiota to Human Diseases: A Systems Biology Perspective

    Wu, H., Tremaroli, V. & Bäckhed, F., 6 Nov 2015, In: Trends in Endocrinology and Metabolism. 26, 12, p. 758-70 13 p.

    Research output: Contribution to journalReviewResearchpeer-review

  97. Published

    Tumor suppressor ASXL1 is essential for the activation of INK4B expression in response to oncogene activity and anti-proliferative signals

    Wu, X., Bekker-Jensen, I. H., Christensen, J., Rasmussen, K. D., Sidoli, S., Qi, Y., Kong, Y., Wang, X., Cui, Y., Xiao, Z., Xu, G., Williams, K., Rappsilber, J., Sønderby, C. K., Winther, Ole, Jensen, O. N. & Helin, K., 2015, In: Cell Research. 25, p. 1205-1218 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  98. Published

    A catalog of the mouse gut metagenome: [incl. Author Correction]

    Xiao, L., Feng, Q., Liang, S., Sonne, S. B., Xia, Z., Qiu, X., Li, X., Long, H., Zhang, J., Zhang, D., Liu, C., Fang, Z., Chou, J., Glanville, J., Hao, Q., Kotowska, D. E., Colding, C. S., Licht, T. R., Wu, D., Yu, J. & 17 others, Sung, J. J. Y., Liang, Q., Li, J., Jia, H., Lan, Z., Tremaroli, V., Dworzynski, P., Nielsen, H. B., Bäckhed, G. F., Dore, J., Le Chatelier, E., Ehrlich, S. D., Lin, J. C., Arumugam, Mani, Wang, J., Madsen, L. & Kristiansen, Karsten, 2015, In: Nature Biotechnology. 33, 10, p. 1103-1108 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  99. Published

    Inherited coding variants at the CDKN2A locus influence susceptibility to acute lymphoblastic leukaemia in children

    Xu, H., Zhang, H., Yang, W., Yadav, R., Morrison, A. C., Qian, M., Devidas, M., Liu, Y., Perez-Andreu, V., Zhao, X., Gastier-Foster, J. M., Lupo, P. J., Neale, G., Raetz, E., Larsen, E., Bowman, W. P., Carroll, W. L., Winick, N., Williams, R., Hansen, T. & 13 others, Holm, Jens-Christian, Mardis, E., Fulton, R., Pui, C., Zhang, J., Mullighan, C. G., Evans, W. E., Hunger, S. P., Gupta, R., Schmiegelow, Kjeld, Loh, M. L., Relling, M. V. & Yang, J. J., 2015, In: Nature Communications. 6, p. 1-7 7 p., 7553.

    Research output: Contribution to journalJournal articleResearchpeer-review

  100. Published

    Embryo genome profiling by single-cell sequencing for preimplantation genetic diagnosis in a β-thalassemia family

    Xu, Y., Chen, S., Yin, X., Shen, X., Pan, X., Chen, F., Jiang, H., Liang, Y., Wang, W., Xu, X., Wang, J., Zhang, X., Zhou, C. & Wang, J., 2015, In: Clinical Chemistry. 61, 4, p. 617-626 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  101. Published

    Early phase glucagon and insulin secretory abnormalities, but not incretin secretion, are similarly responsible for hyperglycemia after ingestion of nutrients

    Yabe, D., Kuroe, A., Watanabe, K., Iwasaki, M., Hamasaki, A., Hamamoto, Y., Harada, N., Yamane, S., Lee, S., Murotani, K., Deacon, Carolyn F., Holst, Jens Juul, Hirano, T., Inagaki, N., Kurose, T. & Seino, Y., 2015, In: Journal of Diabetes and its Complications. 29, p. 413-421 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review