- 2012
- Published
Genome-wide and caste-specific DNA methylomes of the ants Camponotus floridanus and Harpegnathos saltator
Bonasio, R., Li, Q., Lian, J., Mutti, N. S., Jin, L., Zhao, H., Zhang, P., Wen, P., Xiang, H., Ding, Y., Jin, Z., Shen, S. S., Wang, Z., Wang, W., Wang, J., Berger, S. L., Liebig, J., KU, thw266 & Reinberg, D., 2012, In: Current Biology. 22, 19, p. 1755-1764 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic Variant SLC2A2 Is Associated with Risk of Cardiovascular Disease - Assessing the Individual and Cumulative Effect of 46 Type 2 Diabetes Related Genetic Variants
Borglykke, A., Grarup, N., Sparsø, T., Linneberg, Allan René, Fenger, M., Jeppesen, J., Hansen, Torben, Pedersen, Oluf Borbye & Jørgensen, T., 2012, In: P L o S One. 7, 11, p. e50418Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A genome-wide association meta-analysis identifies new childhood obesity loci
Bradfield, J. P., Taal, H. R., Timpson, N. J., Scherag, A., Lecoeur, C., Warrington, N. M., Hypponen, E., Holst, C., Valcarcel, B., Thiering, E., Salem, R. M., Schumacher, F. R., Cousminer, D. L., Sleiman, P. M. A., Zhao, J., Berkowitz, R. I., Vimaleswaran, K. S., Jarick, I., Pennell, C. E., Evans, D. M. & 31 others, , 2012, In: Nature Genetics. 44, 5, p. 526-31 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Enteral nutrients potentiate glucagon-like peptide-2 action and reduce dependence on parenteral nutrition in a rat model of human intestinal failure
Brinkman, A. S., Murali, S. G., Hitt, S., Solverson, P. M., Holst, Jens Juul & Ney, D. M., 1 Sep 2012, In: A J P: Gastrointestinal and Liver Physiology (Online). 303, 5, p. G610-22Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Relationships among tonic and episodic aspects of motivation to eat, gut peptides, and weight before and after bariatric surgery
Bryant, E. J., King, N. A., Falkén, Y., Hellström, P. M., Holst, Jens Juul, Blundell, J. E. & Näslund, E., 12 Oct 2012, In: Surgery for Obesity and Related Diseases.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of high-fat overfeeding on mitochondrial function, glucose and fat metabolism, and adipokine levels in low birth weight subjects.
Brøns, C., Jacobsen, S., Hiscock, N., White, A., Nilsson, E., Dunger, D., Astrup, A., Quistorff, B. & Vaag, A., 2012, In: American Journal of Physiology: Endocrinology and Metabolism. 302, 1, p. E43-E51 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rev-erbα and Rev-erbβ coordinately protect the circadian clock and normal metabolic function
Bugge, A. S., Feng, D., Everett, L. J., Briggs, E. R., Mullican, S. E., Wang, F., Jager, J. & Lazar, M. A., 1 Apr 2012, In: Genes & Development. 26, 7, p. 657-67 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Alcohol intake and its effect on some appetite-regulating hormones in man: influence of gastroprotection with sucralfate
Calissendorff, J., Gustafsson, T., Holst, Jens Juul, Brismar, K. & Röjdmark, S., 2012, In: Endocrine Research. 37, 3, p. 154-62 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A metabolic prosurvival role for PML in breast cancer
Carracedo, A., Weiss, D., Leliaert, A. K., Bhasin, M., De Boer, V. C. J., Laurent, G., Adams, A. C., Sundvall, M., Song, S. J., Ito, K., Finley, L. S., Egia, A., Libermann, T., Gerhart-Hines, Zach, Puigserver, P., Haigis, M. C., Maratos-Flier, E., Richardson, A. L., Schafer, Z. T. & Pandolfi, P. P., 4 Sep 2012, In: Journal of Clinical Investigation. 122, 9, p. 3088-3100 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
(1)H MRS assessment of hepatic steatosis in overweight children and adolescents: comparison between 3T and open 1T MR-systems
Chabanova, E., Bille, D. S., Thisted, E., Holm, Jens-Christian & Thomsen, Henrik S., 2012, In: Abdominal Imaging. 38, 2, p. 315-9 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
MR spectroscopy of liver in overweight children and adolescents: investigation of ¹H T2 relaxation times at 3T
Chabanova, E., Bille, D. S., Thisted, E., Holm, Jens-Christian & Thomsen, Henrik S., 2012, In: European Journal of Radiology Extra. 81, 5, p. 811-4 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association of an Osteopontin gene promoter polymorphism with susceptibility to diabetic nephropathy in Asian Indians
Cheema, B. S., Iyengar, S., Ahluwalia, Tarun Veer Singh, Kohli, H. S., Sharma, R., Shah, V. N., Bhansali, A., Sakhuja, V. & Khullar, M., 9 Oct 2012, In: Clinica chimica acta; international journal of clinical chemistry. 413, 19-20, p. 1600-4 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transcriptome and network changes in climbers at extreme altitudes
Chen, F., Zhang, W., Liang, Y., Huang, J., Li, K., Green, C. D., Liu, J., Zhang, G., Zhou, B., Yi, X., Wang, W., Liu, H., Xu, X., Shen, F., Qu, N., Wang, Y., Gao, G., San, A., JiangBai, L., Sang, H. & 6 others, , 2012, In: P L o S One. 7, 2, p. e31645-e31645Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals
Dastani, Z., Hivert, M-F., Timpson, N., Perry, J. R. B., Yuan, X., Scott, R. A., Henneman, P., Heid, I. M., Kizer, J. R., Lyytikäinen, L-P., Fuchsberger, C., Tanaka, T., Morris, A. P., Small, K., Isaacs, A., Beekman, M., Coassin, S., Lohman, K., Qi, L., Kanoni, S. & 31 others, , 2012, In: P L o S Genetics (Online). 8, 3, p. e1002607Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mechanisms of improved glycaemic control after Roux-en-Y gastric bypass
Dirksen, C., Jørgensen, N. B., Bojsen-Møller, K. N., Jacobsen, S. H., Hansen, D. L., Worm, Dorte, Holst, Jens Juul & Madsbad, Sten, 2012, In: Diabetologia. 55, 7, p. 1890-901 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Major Lineage of Enteroendocrine Cells Coexpress CCK, Secretin, GIP, GLP-1, PYY, and Neurotensin but Not Somatostatin
Egerod, Kristoffer Lihme, Engelstoft, M. S., Grunddal, Kaare Villum, Nøhr, M. K., Secher, A., Sakata, I., Pedersen, Jens, Windeløv, Johanne Agerlin, Füchtbauer, E., Olsen, Jørgen, Sundler, F., Christensen, Jan Pravsgaard, Wierup, N., Olsen, Jesper Velgaard, Holst, Jens Juul, Zigman, J. M., Poulsen, Steen Seier & Schwartz, Thue W., 1 Dec 2012, In: Endocrinology. 153, 12, p. 5782-95 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of beta cell and incretin function in patients with MODY1 (HNF4A MODY) and MODY3 (HNF1A MODY) in a Swedish patient collection
Ekholm, E., Shaat, N. & Holst, Jens Juul, Oct 2012, In: Acta Diabetologica. 49, 5, p. 349-54 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An aromatic region to induce a switch between agonism and inverse agonism at the ghrelin receptor
Els, S., Schild, E., Petersen, P. S., Kilian, T., Mokrosinski, J., Frimurer, Thomas Michael, Chollet, C., Schwartz, Thue W., Holst, Birgitte & Beck-Sickinger, A. G., 13 Sep 2012, In: Journal of Medicinal Chemistry. 55, 17, p. 7437-49 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
RNase L controls terminal adipocyte differentiation, lipids storage and insulin sensitivity via CHOP10 mRNA regulation
Fabre, O. M. J., Salehzada, T., Lambert, K., Boo Seok, Y., Zhou, A., Mercier, J. & Bisbal, C., Sep 2012, In: Cell Death and Differentiation. 19, 9, p. 1470-81 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Incretin and pancreatic hormone secretion in Caucasian non-diabetic carriers of the TCF7L2 rs7903146 risk T allele
Faerch, K., Pilgaard, K., Knop, Filip Krag, Hansen, Torben, Pedersen, Oluf Borbye, Jørgensen, T. & Holst, Jens Juul, 2012, In: Diabetes, Obesity and Metabolism Online. 15, 1, p. 91-95 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Programming of adipose tissue miR-483-3p and GDF-3 expression by maternal diet in type 2 diabetes
Ferland-McCollough, D., Fernandez-Twinn, D. S., Cannell, I. G., David, H., Warner, M., Vaag, Allan, Bork-Jensen, J., Brøns, C., Gant, T. W., Willis, A. E., Siddle, K., Bushell, M. & Ozanne, S. E., 2012, In: Cell Death and Differentiation. 19, p. 1003-12 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Muscle fat content and abdominal adipose tissue distribution investigated by magnetic resonance spectroscopy and imaging in obese children and youths
Fonvig, C. E., Bille, D. S., Chabanova, E., Nielsen, T. R. H., Thomsen, Henrik S. & Holm, Jens-Christian, 2012, In: Pediatric Reports. 4, 1, p. e11Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Muscle inflammatory signaling in response to 9 days of physical inactivity in young men with low compared to normal birth weight
Friedrichsen, M., Ribel-Madsen, R., Mortensen, B., Hansen, C. N., Alibegovic, A. C., Højbjerre, L., Sonne, M. P., Wojtaszewski, Jørgen F P, Stallknecht, Bente Merete, Dela, Flemming & Vaag, Allan, 2012, In: European Journal of Endocrinology. 167, 6, p. 829-838 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Adult glucose metabolism in extremely birthweight-discordant monozygotic twins
Frost, M., Petersen, I., Brixen, K., Beck-Nielsen, H., Holst, Jens Juul, Christiansen, L., Højlund, K. & Christensen, K., Dec 2012, In: Diabetologia. 55, 12, p. 3204-12 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-1 decreases intracerebral glucose content by activating hexokinase and changing glucose clearance during hyperglycemia
Gejl, M., Egefjord, L., Lerche, S., Vang, K., Bibby, B. M., Holst, Jens Juul, Mengel, A., Møller, N., Rungby, J., Brock, B. & Gjedde, Albert, Dec 2012, In: Journal of Cerebral Blood Flow and Metabolism. 32, 12, p. 2146-2152 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
'Omics'-driven discoveries in prevention and treatment of type 2 diabetes
Gjesing, A. M. P. & Pedersen, Oluf Borbye, 2012, In: European Journal of Clinical Investigation. Supplement. 42, 6, p. 579-88 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fasting and oral glucose-stimulated levels of glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) are highly familial traits
Gjesing, A. M. P., Ekstrøm, Claus Thorn, Eiberg, Hans Rudolf Lytchoff, Urhammer, S. A., Holst, Jens Juul, Pedersen, Oluf Borbye & Hansen, Teis Schjals, 2012, In: Diabetologia. 55, 5, p. 1338-1345 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Læsningen af vignetter
Grünfeld, Martin & Monrad, M., 2012, Vignetmetoden. Ejrnæs, M. & Monrad, M. (eds.). Akademisk ForlagResearch output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
The glycemic, insulinemic and plasma amino acid responses to equi-carbohydrate milk meals, a pilot- study of bovine and human milk
Gunnerud, U., Holst, Jens Juul, Östman, E. & Björck, I., 2012, In: Nutrition Journal. 11, p. 83Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of pre-meal drinks with protein and amino acids on glycemic and metabolic responses at a subsequent composite meal
Gunnerud, U. J., Heinzle, C., Holst, Jens Juul, Östman, E. M. & Björck, I. M. E., 2012, In: P L o S One. 7, 9, p. e44731Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Frequent mutations of genes encoding ubiquitin-mediated proteolysis pathway components in clear cell renal cell carcinoma
Guo, G., Gui, Y., Gao, S., Tang, A., Hu, X., Huang, Y., Jia, W., Li, Z., He, M., Sun, L., Song, P., Sun, X., Zhao, X., Yang, S., Liang, C., Wan, S., Zhou, F., Chen, C., Zhu, J., Li, X. & 35 others, , 2012, In: Nature Genetics. 44, 1, p. 17-19 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Calcium sensing in exocytosis
Gustavsson, N., Wu, B. & Han, W., 2012, In: Advances in Experimental Medicine and Biology. 740, p. 731-57 27 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Clinical correlates of weight loss and attrition during a 10-week dietary intervention study: Results from the NUGENOB project
Handjieva-Darlenska, T., Holst, C., Grau, K., Blaak, E., Martinez, J. A., Oppert, J., Taylor, M. A., Sørensen, Thorkild I.A. & Astrup, A., 2012, In: Obesity Facts. 5, 6, p. 928-936 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Intake of ruminant trans fatty acids and changes in body weight and waist circumference
Hansen, C. P., Berentzen, T. L., Halkjær, J., Tjønneland, A., Sørensen, Thorkild I.A., Overvad, K. & Jakobsen, M. U., 2012, In: European Journal of Clinical Nutrition. 66, 10, p. 1104-9 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GPR119 as a fat sensor
Hansen, Harald S., Rosenkilde, Mette, Holst, Jens Juul & Schwartz, Thue W., Jul 2012, In: Trends in Pharmacological Sciences. 33, 7, p. 374-81 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Beta-Cell Specific DMT1 KO Protects Islets from Cytokine Induced ROS and Apoptosis
Hansen, J. B., Heller, S., Madsen, A. N., Holst, Birgitte, Tonnesen, M. F. & Mandrup-Poulsen, Thomas, 2012.Research output: Contribution to conference › Poster › Research › peer-review
- Published
Divalent metal transporter 1 regulates iron-mediated ROS and pancreatic ß cell fate in response to cytokines
Hansen, J. B., Tonnesen, M. F., Madsen, A. N., Hagedorn, P., Friberg, J., Grunnet, L. G., Heller, R. S., Nielsen, A. Ø., Størling, J., Baeyens, L., Anker-Kitai, L., Qvortrup, K., Bouwens, L., Efrat, S., Aalund, M., Andrews, N. C., Billestrup, N., Karlsen, A. E., Holst, B., Pociot, F. & 1 others, , 2012, In: Cell Metabolism. 16, 4, p. 449-61 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impaired incretin-induced amplification of insulin secretion after glucose homeostatic dysregulation in healthy subjects
Hansen, K. B., Vilsbøll, Tina, Bagger, J. I., Holst, Jens Juul & Knop, Filip Krag, 2012, In: Journal of Clinical Endocrinology and Metabolism. 97, 4, p. 1363-70 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The arginine of the DRY motif in transmembrane segment III functions as a balancing micro-switch in the activation of the β2-adrenergic receptor
Hansen, L. V., Groenen, M., Nygaard, R., Frimurer, Thomas Michael, Holliday, N. D. & Schwartz, Thue W., 14 Sep 2012, In: Journal of Biological Chemistry. 287, 38, p. 31973-82 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Obesity: lessons from evolution and the environment
Heitmann, B. L., Westerterp, K. R., Loos, R. J. F., Sørensen, Thorkild I.A., O'Dea, K., McLean, P., Jensen, T. K., Eisenmann, J., Speakman, J. R., Simpson, S. J., Reed, D. R. & Westerterp-Plantenga, M. S., 2012, In: Obesity Reviews. 13, 10, p. 910-22 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Apolipoprotein(a) genetic sequence variants associated with systemic atherosclerosis and coronary atherosclerotic burden but not with venous thromboembolism
Helgadottir, A., Gretarsdottir, S., Thorleifsson, G., Holm, H., Patel, R. S., Gudnason, T., Jones, G. T., van Rij, A. M., Eapen, D. J., Baas, A. F., Tregouet, D-A., Morange, P-E., Emmerich, J., Lindblad, B., Gottsäter, A., Kiemeny, L. A., Lindholt, J. S., Sakalihasan, N., Ferrell, R. E., Carey, D. J. & 63 others, , 2012, In: Journal of the American College of Cardiology. 60, 8, p. 722-9 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A comparative analysis of the intestinal metagenomes present in guinea pigs (Cavia porcellus) and humans (Homo sapiens)
Hildebrand, F., Ebersbach, T., Nielsen, H. B., Li, X., Sonne, Si Brask, dos Santos, M. B. Q., Dimitrov, P., Madsen, L., Qin, J., Wang, J., Raes, J., Kristiansen, Karsten & Licht, T. R., 2012, In: B M C Genomics. 13, 514, 22 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Longitudinal changes in blood pressure during weight loss and regain of weight in obese boys and girls
Holm, J., Gamborg, M., Neland, M., Ward, L., Gammeltoft, S., Heitmann, B. L., Sørensen, Thorkild I.A. & Ibsen, K. K., 2012, In: Journal of Hypertension. 30, 2, p. 368-74 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Acute differential effects of milk-derived dietary proteins on postprandial lipaemia in obese non-diabetic subjects
Holmer-Jensen, J., Hartvigsen, M., Mortensen, L. S., Astrup, A., de Vrese, M., Holst, Jens Juul, Thomsen, C. & Hermansen, K., 2012, In: European Journal of Clinical Nutrition. 66, p. 32-38 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Incretin based therapies: do they hold their promise?
Holst, Jens Juul, 2012, In: Journal of Diabetes. 4, 1, p. 4-7 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Potential new approaches to modifying intestinal GLP-1 secretion in patients with type 2 diabetes mellitus: focus on bile acid sequestrants
Holst, Jens Juul & McGill, M. A., 2012, In: Clinical Drug Investigation. 32, 1, p. 1-14 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Single-cell exome sequencing and monoclonal evolution of a JAK2-negative myeloproliferative neoplasm
Hou, Y., Song, L., Zhu, P., Zhang, B., Tao, Y., Xu, X., Li, F., Wu, K., Liang, J., Shao, D., Wu, H., Ye, X., Ye, C., Wu, R., Jian, M., Chen, Y., Xie, W., Zhang, R., Chen, L., Liu, X. & 20 others, , 2012, In: Cell. 148, 5, p. 873-885 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transmission ratio distortion: review of concept and implications for genetic association studies
Huang, L. O., Labbe, A. & Infante-RIvard, C., 2012, In: Human Genetics.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Leptin og dens betydning for vægtvedligeholdelse
Iepsen, E. P. W., Torekov, Signe Sørensen & Holst, Jens Juul, 2012, In: Klinisk biokemi i Norden. 24, 4, p. 8-15 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Maternal Distress during Pregnancy and Offspring Childhood Overweight
Ingstrup, K. G., Schou Andersen, C., Adeltoft, T. A., Pedersen, P., Sørensen, Thorkild I.A. & Nohr, E. A., 2012, In: Journal of Obesity. 2012, p. 462845Research output: Contribution to journal › Journal article › Research › peer-review
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Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
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Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets
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The isoenzyme pattern of LDH does not play a physiological role; except perhaps during fast transitions in energy metabolism
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Determinants of plasma levels of proglucagon and the metabolic impact of glucagon receptor signalling: a UK Biobank study
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The interplay between birth weight and obesity in determining childhood and adolescent cardiometabolic risk
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Targeting postsynaptic glutamate receptor scaffolding proteins PSD-95 and PICK1 for obesity treatment
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