- 2016
- Published
Childhood body mass index and risk of schizophrenia in relation to childhood age, sex and age of first contact with schizophrenia
Sørensen, H. J., Gamborg, Michael Orland, Sørensen, Thorkild I.A., Baker, J. L. & Mortensen, Erik Lykke, Apr 2016, In: European Psychiatry. 34, p. 64-9 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits
Teumer, A., Qi, Q., Nethander, M., Aschard, H., Bandinelli, S., Beekman, M., Berndt, S. I., Bidlingmaier, M., Broer, L., Cappola, A., Ceda, G. P., Chanock, S., Chen, M-H., Chen, T. C., Chen, Y-D. I., Chung, J., Del Greco Miglianico, F., Eriksson, J., Ferrucci, L., Friedrich, N. & 31 others, , 29 Jun 2016, In: Aging Cell. 15, 5, p. 811-824 14 p., e1006166.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dating of Pregnancy in First versus Second Trimester in Relation to Post-Term Birth Rate: A Cohort Study
Thagaard, I. N., Krebs, Lone, Lausten-Thomsen, U., Olesen-Larsen, S., Holm, Jens-Christian, Christiansen, M. & Larsen, T., 2016, In: PloS one. 11, 1, 9 p., e0147109.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Alcohol consumption and risk of atrial fibrillation: Observational and genetic estimates of association
Tolstrup, J. S., Wium-Andersen, M. K., Ørsted, D. D. & Nordestgaard, Børge, Sep 2016, In: European Journal of Preventive Cardiology. 23, 14, p. 1514-23 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In vivo and in vitro degradation of peptide YY3-36 to inactive peptide YY3-34 in humans
Toräng, S., Bojsen-Møller, K. N., Svane, M. S., Hartmann, Bolette, Rosenkilde, Mette, Madsbad, Sten & Holst, Jens Juul, 27 Jan 2016, In: A J P: Regulatory, Integrative and Comparative Physiology (Online). 310, 1, p. R866-R874 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nicotinamide riboside is a major NAD+ precursor vitamin in cow milk
Trammell, Sam, Y., L., Redpath, P., Migaud, M. E. & Brenner, C., 1 May 2016, In: Journal of Nutrition. 146, 5, p. 957-963 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nicotinamide riboside is uniquely and orally bioavailable in mice and humans
Trammell, Sam, Schmidt, M. S., Weidemann, B. J., Redpath, P., Jaksch, F., Dellinger, R. W., Li, Z., Abel, E. D., Migaud, M. E. & Brenner, C., 10 Oct 2016, In: Nature Communications. 7, 12948.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nicotinamide riboside opposes type 2 diabetes and neuropathy in mice
Trammell, Sam, Weidemann, B. J., Chadda, A., Yorek, M. S., Holmes, A., Coppey, L. J., Obrosov, A., Kardon, R. H., Yorek, M. A. & Brenner, C., 27 May 2016, In: Scientific Reports. 6, 26933.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of a Family-Based Childhood Obesity Treatment Program on Parental Weight Status
Trier, C., Dahl, M., Stjernholm, T., Nielsen, T. R. H., Bøjsøe, C., Fonvig, C. E., Pedersen, Oluf Borbye, Hansen, Torben & Holm, Jens-Christian, 2016, In: P L o S One. 11, 8, p. 1-11 11 p., e0161921.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic Evidence for Causal Relationships Between Maternal Obesity-Related Traits and Birth Weight
Tyrrell, J., Richmond, R. C., Palmer, T. M., Feenstra, B., Rangarajan, J., Metrustry, S., Cavadino, A., Paternoster, L., Armstrong, L. L., De Silva, N. M. G., Wood, A. R., Horikoshi, M., Geller, F., Myhre, R., Bradfield, J. P., Kreiner-Møller, E., Huikari, V., Painter, J. N., Hottenga, J. J., Allard, C. & 31 others, , 2016, In: J A M A: The Journal of the American Medical Association. 315, 11, p. 1129-40 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Oral treatment with improves insulin sensitivity in mice
Udayappan, S., Manneras-Holm, L., Chaplin-Scott, A., Belzer, C., Herrema, H., Dallinga-Thie, G. M., Duncan, S. H., Stroes, E. S. G., Groen, A. K., Flint, H. J., Backhed, F., de Vos, W. M. & Nieuwdorp, M., 2016, In: npj Biofilms and Microbiomes. 2, 10 p., 16009.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Body mass index at school age and hospital admissions for asthma in early adulthood: A prospective study of 321,830 children
Ulrik, Charlotte Suppli, Lophaven, S. N., Andersen, Zorana Jovanovic, Sørensen, Thorkild I.A. & Baker, J. L., 2016.Research output: Contribution to conference › Paper › Research › peer-review
- Published
A comprehensive compartmental model of blood glucose regulation for healthy and type 2 diabetic subjects
Vahidi, O., Kwok, K. E., Gopaluni, R. B. & Knop, Filip Krag, 2016, In: Medical & Biological Engineering & Computing. 54, 9, p. 1383-1398 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Major rapid weight loss induces changes in cardiac repolarization
Vedel-Larsen, E., Iepsen, E. P. W., Lundgren, J., Graff, C., Struijk, J. J., Hansen, Torben, Holst, Jens Juul, Madsbad, Sten, Torekov, Signe Sørensen & Kanters, Jørgen K., 10 Feb 2016, In: Journal of Electrocardiology. 49, 3, p. 467-472 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cephalic phase secretion of insulin and other enteropancreatic hormones in humans
Veedfald, Simon, Plamboeck, A., Deacon, Carolyn F., Hartmann, Bolette, Knop, Filip Krag, Vilsbøll, Tina & Holst, Jens Juul, 1 Jan 2016, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 310, 1, p. G43-51Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The insulinotropic effect of exogenous GLP-1 is not affected by acute vagotomy in anaesthetized pigs
Veedfald, Simon, Hansen, M., Christensen, L. W., Larsen, S. A. H., Hjøllund, K. R., Plamboeck, A., Hartmann, Bolette, Deacon, Carolyn F. & Holst, Jens Juul, 30 Mar 2016, In: Experimental Physiology. 101, 7, p. 895-912 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Systematic Comparison of Purification and Normalization Protocols for Quantitative MicroRNA Expressional Profiling in Insulin-Producing Cells
Vestergaard, A. L., Blankestijn, M., Stahl, J. L., Pallesen, E. M. H., Bang-Berthelsen, C. H., Pociot, Flemming, Novotny, G. W., Lundh, M. & Mandrup-Poulsen, Thomas, 2016, In: International Journal of Molecular Sciences (Online). 17, 6, 8 p., 896.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Functional and genetic epidemiological characterisation of the FFAR4 (GPR120) p.R270H variant in the Danish population
Vestmar, M. A., Galijatovic, E. A. A., Christensen, C. R., Pedersen, M. H., Glümer, C., Linneberg, Allan René, Witte, D. R., Jørgensen, M. E., Christensen, C., Brandslund, I., Lauritzen, T., Pedersen, Oluf Borbye, Holst, Birgitte, Grarup, N., Schwartz, Thue W. & Hansen, Torben, Sep 2016, In: Journal of Medical Genetics. 53, 9, p. 616-23 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Intestinal Crosstalk between Bile Acids and Microbiota and Its Impact on Host Metabolism
Wahlström, A., Sayin, S. I., Marschall, H. & Bäckhed, G. F., 12 Jul 2016, In: Cell Metabolism. 24, 1, p. 41-50 10 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Genome-wide association study of the modified Stumvoll Insulin Sensitivity Index identifies BCL2 and FAM19A2 as novel insulin sensitivity loci
Walford, G. A., Gustafsson, S., Rybin, D., Stančáková, A., Chen, H., Liu, C-T., Hong, J., Jensen, R. A., Rice, K., Morris, A. P., Mägi, R., Tönjes, A., Prokopenko, I., Kleber, M. E., Delgado, G., Silbernagel, G., Jackson, A. U., Appel, E. V., Grarup, N., Lewis, J. P. & 59 others, , Oct 2016, In: Diabetes. 65, 10, p. 3200-3211 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Physiology insights
Watanabe, R. M. & Hansen, Torben, 2016, The Genetics of Type 2 Diabetes and Related Traits: Biology, Physiology and Translation. Springer, p. 207-221 15 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Inability of Some Commercial Assays to Measure Suppression of Glucagon Secretion
Albrechtsen, Nicolai Jacob Wewer, Veedfald, Simon, Plamboeck, A., Deacon, Carolyn F., Hartmann, Bolette, Knop, Filip Krag, Vilsbøll, Tina & Holst, Jens Juul, 2016, In: Journal of Diabetes Research. 2016, 5 p., 8352957.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Oxyntomodulin Identified as a Marker of Type 2 Diabetes and Gastric Bypass Surgery by Mass-spectrometry Based Profiling of Human Plasma
Albrechtsen, Nicolai Jacob Wewer, Hornburg, D., Albrechtsen, Reidar, Svendsen, B., Toräng, S., Jepsen, Sara Lind, Kuhre, Rune Ehrenreich, Hansen, M., Janus, C., Floyd, A., Lund, Asger Bach, Vilsbøll, Tina, Knop, Filip Krag, drb459, drb459, Deacon, Carolyn F., Meissner, F., Mann, Matthias, Holst, Jens Juul & Hartmann, Bolette, May 2016, In: EBioMedicine. 7, p. 112-120 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The biology of glucagon and the consequences of hyperglucagonemia
Albrechtsen, Nicolai Jacob Wewer, Kuhre, Rune Ehrenreich, Pedersen, Jens, Knop, Filip Krag & Holst, Jens Juul, 9 Sep 2016, In: Biomarkers in Medicine. 10, 11, p. 1141-1151 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Do glucagonomas always produce glucagon?
Albrechtsen, Nicolai Jacob Wewer, Challis, B., Damjanov, I. & Holst, Jens Juul, 1 Feb 2016, In: Bosnian Journal of Basic Medical Sciences. 16, 1, p. 1-7 7 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Use of anesthesia dramatically alters the oral glucose tolerance and insulin secretion in C57Bl/6 mice
Windeløv, Johanne Agerlin, Pedersen, Jens & Holst, Jens Juul, Jun 2016, In: Physiological Reports. 4, 11, 6 p., e12824.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Peptide YY3-36 and glucagon-like peptide-1 in functional dyspepsia. Secretion and role in symptom generation
Witte, A., Hilsted, Linda, Holst, Jens Juul & Schmidt, P. T., Apr 2016, In: Scandinavian Journal of Gastroenterology. 51, 4, p. 400-409 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Twin's Birth-Order Differences in Height and Body Mass Index From Birth to Old Age: A Pooled Study of 26 Twin Cohorts Participating in the CODATwins Project
Yokoyama, Y., Jelenkovic, A., Sund, R., Sung, J., Hopper, J. L., Ooki, S., Heikkilä, K., Aaltonen, S., Tarnoki, A. D., Tarnoki, D. L., Willemsen, G., Bartels, M., van Beijsterveldt, T. C. E. M., Saudino, K. J., Cutler, T. L., Nelson, T. L., Whitfield, K. E., Wardle, J., Llewellyn, C. H., Fisher, A. & 48 others, , 2016, In: Twin Research and Human Genetics. 19, 2, p. 112-24 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of Gastric Bypass and Gastric Banding on Bone Remodeling in Obese Patients with Type 2 Diabetes
Yu, E. W., Wewalka, M., Ding, S., Simonson, D. C., Foster, K., Holst, Jens Juul, Vernon, A., Goldfine, A. B. & Halperin, F., Feb 2016, In: Journal of Clinical Endocrinology and Metabolism. 101, 2, p. 714–722Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Insights into metabolic disease from studying genetics in isolated populations: stories from Greece to Greenland
Zeggini, E., Gloyn, A. L. & Hansen, Torben, 18 Mar 2016, In: Diabetologia. 59, 5, p. 938-941 4 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Building Bridges through Scientific Conferences
Zierath, Juleen R, 17 Nov 2016, In: Cell. 167, 5, p. 1155-1158 4 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Sex-specific associations between birth weight and adult primary liver cancer in a large cohort of Danish children
Zimmermann, E., Berentzen, T. L., Gamborg, Michael Orland, Sørensen, Thorkild I.A. & Baker, J. L., 15 Mar 2016, In: International Journal of Cancer. 138, 6, p. 1410–1415 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Altered Microbiota Contributes to Reduced Diet-Induced Obesity upon Cold Exposure
Ziętak, M., Kovatcheva-Datchary, P., Markiewicz, L. H., Ståhlman, M., Kozak, L. P. & Bäckhed, G. F., 14 Jun 2016, In: Cell Metabolism. 23, 6, p. 1216-23 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High-fat diet reprograms the epigenome of rat spermatozoa and transgenerationally affects metabolism of the offspring
de Castro Barbosa, T., Ingerslev, L. R., Alm, P. S., Versteyhe, S., Massart, J., Rasmussen, M., Donkin, I., Sjögren, R., Mudry, J. M., Vetterli, L., Gupta, S., Krook, A., Zierath, Juleen R & Barrès, Romain, Mar 2016, In: Molecular Metabolism. 5, 3, p. 184-97 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reproducibility of coronary atherosclerotic plaque characteristics in populations with low, intermediate, and high prevalence of coronary artery disease by multidetector computer tomography: a guide to reliable visual coronary plaque assessments
de Knegt, M. C., Linde, J. J., Fuchs, A., Nordestgaard, Børge, Køber, Lars Valeur, Hove, Jens Dahlgaard & Kofoed, Klaus Fuglsang, Oct 2016, In: International Journal of Cardiovascular Imaging. 32, 10, p. 1555-66 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration
de Vries, P. S., Chasman, D. I., Sabater-Lleal, M., Chen, M-H., Huffman, J. E., Steri, M., Tang, W., Teumer, A., Marioni, R. E., Grossmann, V., Hottenga, J. J., Trompet, S., Müller-Nurasyid, M., Zhao, J. H., Brody, J. A., Kleber, M. E., Guo, X., Wang, J. J., Auer, P. L., Attia, J. R. & 111 others, , 2016, In: Human Molecular Genetics. 25, 2, p. 358-370 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Distal, not proximal, colonic acetate infusions promote fat oxidation and improve metabolic markers in overweight/obese men
van der Beek, C. M., Canfora, E. E., Lenaerts, K., Troost, F. J., Damink, S. W. M. O., Holst, Jens Juul, Masclee, A. A. M., Dejong, C. H. C. & Blaak, E. E., 11 Oct 2016, In: Clinical Science. 130, 22, p. 2073-2082 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
52 Genetic Loci Influencing Myocardial Mass
van der Harst, P., van Setten, J., Verweij, N., Vogler, G., Franke, L., Maurano, M. T., Wang, X., Mateo Leach, I., Eijgelsheim, M., Sotoodehnia, N., Hayward, C., Sorice, R., Meirelles, O., Lyytikäinen, L-P., Polašek, O., Tanaka, T., Arking, D. E., Ulivi, S., Trompet, S., Müller-Nurasyid, M. & 140 others, , 27 Sep 2016, In: Journal of the American College of Cardiology. 68, 13, p. 1435-48 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
FGF21 Mediates Endocrine Control of Simple Sugar Intake and Sweet Taste Preference by the Liver
von Holstein-Rathlou, S., BonDurant, L. D., Peltekian, L., Naber, M. C., Yin, T. C., Claflin, K. E., Urizar, A. I., Madsen, A. N., Ratner, C., Holst, B., Karstoft, K., Vandenbeuch, A., Anderson, C. B., Cassell, M. D., Thompson, A. P., Solomon, T. P., Rahmouni, K., Kinnamon, S. C., Pieper, A. A., Gillum, M. P. & 1 others, , 9 Feb 2016, In: Cell Metabolism. 23, 2, p. 335-43 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Urinary biomarkers are associated with incident cardiovascular disease, all-cause mortality and deterioration of kidney function in type 2 diabetic patients with microalbuminuria
von Scholten, B. J., Reinhard, H., Hansen, Tine Willum, Oellgaard, J., Parving, H., Jacobsen, P. K. & Rossing, Peter, Jul 2016, In: Diabetologia. 59, 7, p. 1549–1557Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High body mass index and risk of exacerbations and pneumonias in individuals with chronic obstructive pulmonary disease: observational and genetic risk estimates from the Copenhagen General Population Study
Çolak, Y., Afzal, Shoaib, Lange, Peter & Nordestgaard, Børge, Oct 2016, In: International Journal of Epidemiology. 45, 5, p. 1551-1559 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Majority of never-smokers with airflow limitation do not have asthma: the Copenhagen General Population Study
Çolak, Y., Afzal, Shoaib, Nordestgaard, Børge & Lange, Peter, Jul 2016, In: Thorax. 71, 7, p. 614-623 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Provision of amniotic fluid during parenteral nutrition increases weight gain with limited effects on gut structure, function, immunity, and microbiology in newborn preterm pigs
Østergaard, M. V., Shen, René Liang, Støy, A. C. F., Skovgaard, K., Krych, Ł., Leth, S. S., Nielsen, Dennis Sandris, Hartmann, Bolette, Bering, S. B., Schmidt, M. & Sangild, Per Torp, 2016, In: Journal of Parenteral and Enteral Nutrition. 40, 4, p. 552-566 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
Childhood BMI growth trajectories and endometrial cancer risk
Aarestrup, J., Gamborg, M., Tilling, K., Ulrich, L. G., Sørensen, Thorkild I.A. & Baker, J. L., 15 Jan 2017, In: International Journal of Cancer. 140, 2, p. 310–315 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Carriers of a VEGFA enhancer polymorphism selectively binding CHOP/DDIT3 are predisposed to increased circulating levels of thyroid-stimulating hormone
Ahluwalia, Tarun Veer Singh, Troelsen, J. T., Balslev-Harder, M., Bork-Jensen, J., Thuesen, B. H., Cerqueira, C., Linneberg, Allan René, Grarup, N., Pedersen, Oluf Borbye, Hansen, Torben & Dalgaard, L. T., Mar 2017, In: Journal of Medical Genetics. 54, 3, p. 166-175 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Circulating Glucagon 1-61 Regulates Blood Glucose by Increasing Insulin Secretion and Hepatic Glucose Production
Albrechtsen, N. J. W., Kuhre, R. E., Hornburg, D., Jensen, C. Z., Hornum, M., Dirksen, C., Svane, M., Gasbjerg, L. S., Jorgensen, N. B., Gabe, M. N., Balk-Moller, E., Albrechtsen, R., Winther-Sorensen, M., Galsgaard, K. D., Meissner, F., Jorsal, T., Lund, A., Vilsboll, T., Eliasen, R., Bojsen-Moller, K. N. & 9 others, , Nov 2017, In: Cell Reports. 21, 6, p. 1452-1460Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic determinants of serum vitamin B12 and their relation to body mass index
Allin, K. H., Friedrich, N., Pietzner, M., Grarup, N., Thuesen, B. H., Linneberg, Allan René, Pisinger, C., Hansen, Torben, Pedersen, Oluf Borbye & Sandholt, C. H., Feb 2017, In: European Journal of Epidemiology. 32, 2, p. 125–134Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Grandpaternal-induced transgenerational dietary reprogramming of the unfolded protein response in skeletal muscle
Alm, P. S., de Castro Barbosa, T., Barrès, Romain, Krook, A. & Zierath, Juleen R, Jul 2017, In: Molecular Metabolism. 6, 7, p. 621-630 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic determinants of circulating GIP and GLP-1 concentrations
Almgren, P., Lindqvist, A., Krus, U., Hakaste, L., Ottosson-Laakso, E., Asplund, O., Sonestedt, E., Prasad, R. B., Laurila, E., Orho-Melander, M., Melander, O., Tuomi, T., Holst, Jens Juul, Nilsson, P. M., Wierup, N., Groop, L. & Ahlqvist, E., 2 Nov 2017, In: JCI insight. 2, 21, 13 p., e93306.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A study of associations between early DHA status and fatty acid desaturase (FADS) SNP and developmental outcomes in children of obese mothers
Andersen, K. R., Harsløf, L. B. S., Schnurr, T. M., Hansen, Torben, Hellgren, L. I., Michaelsen, Kim F. & Lauritzen, Lotte, 2017, In: The British Journal of Nutrition. 117, 2, p. 278-286 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Diabetes-associated microbiota in fa/fa rats is modified by Roux-en-Y gastric bypass
Arora, Tulika, Seyfried, F., Docherty, N. G., Tremaroli, V., le Roux, C. W., Perkins, R. & Bäckhed, F., Sep 2017, In: I S M E Journal. 11, 9, p. 2035-2046 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-1 elicits vasodilation in adipose tissue and skeletal muscle in healthy men
Asmar, A., Asmar, M., Simonsen, L., Madsbad, Sten, Holst, Jens Juul, Hartmann, Bolette, Sorensen, Charlotte Mehlin & Bülow, J., Feb 2017, In: Physiological Reports. 5, 3, 12 p., e13073.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Gluco- and Liporegulatory and Vasodilatory Effects of Glucose-Dependent Insulinotropic Polypeptide (GIP) Are Abolished by an Antagonist of the Human GIP Receptor
Asmar, M., Asmar, A., Simonsen, L., Gasbjerg, Lærke Smidt, wbf943, wbf943, Rosenkilde, Mette, Hartmann, Bolette, Dela, Flemming, Holst, Jens Juul & Bülow, J., Sep 2017, In: Diabetes. 66, 9, p. 2363-2371 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increased liver fat content in totally pancreatectomised patients
Bagger, J. I., Lund, A. B., Albrechtsen, Nicolai Jacob Wewer, Christensen, M., Grøndahl, M. F., Hansen, C. P., Storkholm, J., Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2017, In: Diabetologia. 60, S1, p. S572-S573Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Regulation of glycolysis in brown adipocytes by HIF-1α
Basse, A. L., Isidor, Marie Sophie, Winther, Sally, Skjoldborg, N. B., Murholm, M., Andersen, E. S., Pedersen, S. B., Wolfrum, C., Quistorff, B. & Hansen, Jacob B., 22 Jun 2017, In: Scientific Reports. 7, 15 p., 4052.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mind the Gut
Bencard, Adam, Gerdes, N., Vilstrup-Møller, N. C., Whiteley, Louise, Bjerregaard, Malthe Kouassi & Thon, C., 2017Research output: Non-textual form › 2D/3D (psysical products) › Research
- Published
Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016: a pooled analysis of 2416 population-based measurement studies in 128·9 million children, adolescents, and adults
Bentham, J., Di Cesare, M., Bilano, V., Jørgensen, T., Linneberg, Allan René, Michaelsen, Kim F., Molbo, Drude, Mortensen, Erik Lykke, Osler, Merete, Sørensen, Thorkild I.A., Zhussupov, B., Zimmermann, E., Cisneros, J. Z., Damsgaard, Camilla Trab, Ängquist, Lars & NCD Risk Factor Collaboration (NCD-RisC), N. R. F. C. (., 2017, In: Lancet. 390, 10113, p. 2627-2642 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pannexin-2-deficiency sensitizes pancreatic beta-cells to cytokine-induced apoptosis in vitro and impairs glucose tolerance in vivo
Berchtold, L. A., Miani, M., Diep, T. A., Madsen, A. N., Cigliola, V., Colli, M., Miskovic Krivokapic, Jelena, Pociot, Flemming, Eizirik, D. L., Meda, P., Holst, Birgitte, Billestrup, Nils & Storling, J., 2017, In: Molecular and Cellular Endocrinology. 448, p. 108-121 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Height at Ages 7-13 Years in Relation to Developing Type 2 Diabetes Throughout Adult Life
Bjerregaard, L. G., Jensen, B. W. & Baker, J. L., Jul 2017, In: Paediatric and Perinatal Epidemiology. 31, 4, p. 284-292 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Are Adverse Effects of Child Overweight on Risk of Type 2 Diabetes Reversible by Remission to Normal Weight in Young Adulthood?
Bjerregaard, L. G., Jensen, B. W., Ängquist, Lars, Osler, Merete, Sørensen, Thorkild I.A. & Baker, J. L., 2017, p. A3. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
- Published
Variations in the prevalence of obesity among european countries, and a consideration of possible causes
Blundell, J. E., Baker, J. L., Boyland, E., Blaak, E., Charzewska, J., De Henauw, S., Frühbeck, G., Gonzalez-Gross, M., Hebebrand, J., Holm, Lotte, Kriaucioniene, V., Lissner, L., Oppert, J. M., Schindler, K., Silva, A. M. & Woodward, E., 2017, In: Obesity Facts. 10, p. 25-37 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Does the sex of one's co-twin affect height and BMI in adulthood? A study of dizygotic adult twins from 31 cohorts
Bogl, L. H., Jelenkovic, A., Vuoksimaa, E., Ahrenfeldt, L., Pietiläinen, K. H., Stazi, M. A., Fagnani, C., D'Ippolito, C., Hur, Y-M., Jeong, H-U., Silberg, J. L., Eaves, L. J., Maes, H. H., Bayasgalan, G., Narandalai, D., Cutler, T. L., Kandler, C., Jang, K. L., Christensen, K., Skytthe, A. & 56 others, , 2017, In: Biology of Sex Differences. 8, 12 p., 14.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Variable reliability of surrogate measures of insulin sensitivity after Roux-en-Y gastric bypass
Bojsen-Møller, K. N., Dirksen, C., Svane, M. S., Jørgensen, N. B., Holst, Jens Juul, Richter, Erik A. & Madsbad, Sten, 2017, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 312, 5, p. R797-R805 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Abscisic acid controls the release of insulin from beta-cells, Glucagon-Like Peptide-1 from intestinal L-cells and glucagon from alpha-cells
Booz, V., Christiansen, Charlotte Bayer, Kuhre, Rune Ehrenreich, Saltiel, M. Y., Sturla, L., Sociali, G., Zocchi, E., Holst, Jens Juul & Bruzzone, S., 2017, In: European Journal of Clinical Investigation. 47, p. 112-113Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Bioinformatics for discovery of microbiome variation
Brejnrod, A. D., 2017, Department of Biology, Faculty of Science, University of Copenhagen.Research output: Book/Report › Ph.D. thesis › Research
- Published
The KDM5 family is required for activation of pro-proliferative cell cycle genes during adipocyte differentiation
Brier, A. B., Loft, A., Madsen, J. G. S., Rosengren, T., Nielsen, R., Schmidt, S. F., Liu, Z., Yan, Q., Gronemeyer, H. & Mandrup, S., 28 Feb 2017, In: Nucleic Acids Research. 45, 4, p. 1743-1759 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Metformin potentiates bile acid-induced GLP-1 secretion in patients with type 2 diabetes
Bronden, A., Alber, A., Rohde, U., Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2017, In: Diabetologia. 60, p. 113-113 242.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Clinical Pharmacokinetics and Pharmacodynamics of Albiglutide
Brønden, A., Knop, Filip Krag & Christensen, Mikkel Bring, 2017, In: Clinical Pharmacokinetics. 56, 7, p. 719-731Research output: Contribution to journal › Review › Research › peer-review
- Published
Single-Dose Metformin Enhances Bile Acid-Induced Glucagon-Like Peptide-1 Secretion in Patients With Type 2 Diabetes
Brønden, A., Albér, A., Rohde, U., Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, Nov 2017, In: The Journal of clinical endocrinology and metabolism. 102, 11, p. 4153-4162 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Selection in Europeans on fatty acid desaturases associated with dietary changes
Buckley, M. T., Racimo, Fernando, Allentoft, Morten Erik, Jensen, M. K., Jonsson, Anna Elisabet, Huang, H., Hormozdiari, F., Sikora, Martin, Marnetto, D., Eskin, E., Jørgensen, M. E., Grarup, N., Pedersen, Oluf Borbye, Hansen, Torben, Kraft, P., Willerslev, Eske & Nielsen, Rasmus, Jun 2017, In: Molecular Biology and Evolution. 34, 6, p. 1307-1318 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
DPP4 gene variation affects GLP-1 secretion, insulin secretion, and glucose tolerance in humans with high body adiposity
Böhm, A., Wagner, R., Machicao, F., Holst, Jens Juul, Gallwitz, B., Stefan, N., Fritsche, A., Häring, H. & Staiger, H., 2017, In: PloS one. 12, 7, 13 p., e0181880.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A molecular census of arcuate hypothalamus and median eminence cell types
Campbell, J. N., Macosko, E. Z., Fenselau, H., Pers, Tune H, Lyubetskaya, A., Tenen, D., Goldman, M., Verstegen, A. M. J., Resch, J. M., McCarroll, S. A., Rosen, E. D., Lowell, B. B. & Tsai, L. T., Mar 2017, In: Nature Neuroscience. 20, 3, p. 484-496 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mechanism by which arylamine N-acetyltransferase 1 ablation causes insulin resistance in mice
Camporez, J. P., Wang, Y., Faarkrog, K., Chukijrungroat, N., Petersen, K. F. & Shulman, G. I., Dec 2017, In: Proceedings of the National Academy of Sciences of the United States of America. 114, 52, p. E11285-E11292 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Colonic infusions of short-chain fatty acid mixtures promote energy metabolism in overweight/obese men: a randomized crossover trial
Canfora, E. E., van der Beek, C. M., Jocken, J. W. E., Goossens, G. H., Holst, Jens Juul, Olde Damink, S. W. M., Lenaerts, K., Dejong, C. H. C. & Blaak, E. E., 24 May 2017, In: Scientific Reports. 7, 12 p., 2360.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Supplementation of Diet With Galacto-oligosaccharides Increases Bifidobacteria, but Not Insulin Sensitivity, in Obese Prediabetic Individuals
Canfora, E. E., van der Beek, C. M., Hermes, G. D. A., Goossens, G. H., Jocken, J. W. E., Holst, Jens Juul, van Eijk, H. M., Venema, K., Smidt, H., Zoetendal, E. G., Dejong, C. H. C., Lenaerts, K. & Blaak, E. E., Jul 2017, In: Gastroenterology. 153, 1, p. 87-97.e3Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Postmenopausal hormone therapy and risk of stroke: A pooled analysis of data from population-based cohort studies
Carrasquilla, Germán D., Frumento, P., Berglund, A., Borgfeldt, C., Bottai, M., Chiavenna, C., Eliasson, M., Engstrom, G., Hallmans, G., Jansson, J., Magnusson, P. K., Nilsson, P. M., Pedersen, N. L., Wolk, A. & Leander, K., Nov 2017, In: PLoS Medicine. 14, 11Research output: Contribution to journal › Journal article › Research › peer-review
- Published
DNA methylation changes at infertility genes in newborn twins conceived by in vitro fertilisation
Castillo-Fernandez, J. E., Loke, Y. J., Bass-Stringer, S., Gao, F., Xia, Y., Wu, H., Lu, H., Liu, Y., Wang, J., Spector, T. D., Saffery, R., Craig, J. M. & Bell, J. T., 24 Mar 2017, In: Genome Medicine. 9, 15 p., 28.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
1H MRS Assessment of Hepatic Fat Content. Comparison Between Normal- and Excess-weight Children and Adolescents
Chabanova, E., Fonvig, Cilius Esmann, Bøjsøe, C., Holm, Jens-Christian & Thomsen, Henrik S., Aug 2017, In: Academic Radiology. 24, 8, p. 982-987 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A functional IFN-λ4-generating DNA polymorphism could protect older asthmatic women from aeroallergen sensitization and associate with clinical features of asthma
Chinnaswamy, S., Wardzynska, A., Pawelczyk, M., Makowska, J., Skaaby, T., Mercader, J. M., Ahluwalia, T. S., Grarup, N., Guindo-Martinez, M., Bisgaard, H., Torrents, D., Linneberg, Allan René, Bønnelykke, Klaus & Kowalski, M. L., 5 Sep 2017, In: Scientific Reports. 7, 1, p. 1-11 11 p., 10500.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Instrumentalization of eating improves weight loss maintenance in obesity
Christensen, Bodil Just, Iepsen, E. P. W., Lundgren, J. R., Holm, Lotte, Madsbad, Sten, Holst, Jens Juul & Torekov, Signe Sørensen, 2017, In: Obesity Facts. 10, 6, p. 633-647 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Overexpression of protein kinase STK25 in mice exacerbates ectopic lipid accumulation, mitochondrial dysfunction and insulin resistance in skeletal muscle
Chursa, U., Nuñez-Durán, E., Cansby, E., Amrutkar, M., Sütt, S., Ståhlman, M., Olsson, B., Borén, J., Johansson, M. E., Bäckhed, G. F., Johansson, B. R., Sihlbom, C. & Mahlapuu, M., Mar 2017, In: Diabetologia. 60, 3, p. 553-567 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Robust GLP-1 secretion by basic L-amino acids does not require the GPRC6A receptor
Clemmensen, Christoffer, Jørgensen, C. V., Smajilovic, S. & Bräuner, Hans, 2017, In: Diabetes, Obesity and Metabolism. 19, 4, p. 599-603Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Critical role for GLP-1 in symptomatic post-bariatric hypoglycaemia
Craig, C. M., Liu, L., Deacon, Carolyn F., Holst, Jens Juul & McLaughlin, T. L., Mar 2017, In: Diabetologia. 60, 3, p. 531-540Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ponderal index at birth associates with later risk of gestational diabetes mellitus
Crusell, Mie Korslund Wiinblad, Damm, Peter, Hansen, Torben, Pedersen, Oluf Borbye, Glümer, C., Vaag, Allan & Lauenborg, J., Aug 2017, In: Archives of Gynecology and Obstetrics. 296, 2, p. 249-256 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Subclinical Hypothyroidism in Danish Lean and Obese Children and Adolescents
Dahl, M., Ohrt, J. D., Fonvig, C. E., Kloppenborg, J. T., Pedersen, Oluf Borbye, Hansen, Torben & Holm, Jens-Christian, 1 Mar 2017, In: JCRPE Journal of Clinical Research in Pediatric Endocrinology. 9, 1, p. 8-16 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cardiovascular safety and benefits of GLP-1 receptor agonists
Dalsgaard, N. B., Brønden, A., Vilsbøll, Tina & Knop, Filip Krag, 2017, In: Expert Opinion on Drug Safety. 16, 3, p. 351-363 13 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Acetylcholine-related proteins in non-neoplastic appearing colonic mucosa from patients with colorectal neoplasia
Damm, M. M. B., Jensen, T. S. R., Mahmood, B., Lundh, M., Poulsen, Steen Seier, Bindslev, Niels & Hansen, M. B., 2017, In: Molecular Carcinogenesis. 56, 10, p. 2223-2233 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cohort description: The Danish study of Functional Disorders
Dantoft, T. M., Ebstrup, J. F., Linneberg, Allan René, Skovbjerg, S., Madsen, A. L., Mehlsen, J., Brinth, L., Eplov, L. F., Carstensen, T. W., Schroder, A., Fink, P. K., Mortensen, Erik Lykke, Hansen, Torben, Pedersen, Oluf Borbye & Jørgensen, T., Feb 2017, In: Clinical Epidemiology. 9, p. 127-139 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Biased agonism and allosteric modulation of GPR183- a 7TM receptor also known as EBV-induced EBI2
Daugvilaite, V., Madsen, C. M., Lückmann, Michael, Castello Echeverria, C., Sailer, A. W., Frimurer, Thomas Michael, Rosenkilde, Mette & Benned-Jensen, T., 2017, In: British Journal of Pharmacology. 174, 13, p. 2031–2042Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Abnormal epigenetic changes during differentiation of human skeletal muscle stem cells from obese subjects
Davegårdh, C., Broholm, C., Perfilyev, A., Henriksen, T., García-Calzón, S., Peijs, L., Hansen, N. S., Volkov, P., Kjøbsted, Rasmus, Wojtaszewski, Jørgen F P, Pedersen, M., Pedersen, Bente Klarlund, Ballak, D. B., Dinarello, C. A., Heinhuis, B., Joosten, L. A. B., Nilsson, E., Vaag, Allan, Schéele, Camilla Charlotte Nielsen & Ling, C., 2017, In: BMC Medicine. 15, 27 p., 39.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ER Stress Inhibits Liver Fatty Acid Oxidation while Unmitigated Stress Leads to Anorexia-Induced Lipolysis and Both Liver and Kidney Steatosis
DeZwaan-McCabe, D., Sheldon, R. D., Gorecki, M. C., Guo, D., Gansemer, E. R., Kaufman, R. J., Rahmouni, K., Gillum, M. P., Taylor, E. B., Teesch, L. M. & Rutkowski, D. T., 30 May 2017, In: Cell Reports. 19, 9, p. 1794-1806 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of liraglutide on cardiovascular risk factors in patients with type 1 diabetes
Dejgaard, T. F., Johansen, N. B., Frandsen, C. S. S., Asmar, A., Tarnow, L., Knop, Filip Krag, Madsbad, Sten & Andersen, H. U., May 2017, In: Diabetes, Obesity and Metabolism. 19, 5, p. 734–738Research output: Contribution to journal › Letter › Research › peer-review
- Published
Dairy consumption, systolic blood pressure, and risk of hypertension: Mendelian randomization study
Ding, M., Huang, T., Bergholdt, H. K. M., Sørensen, Thorkild I.A., Linneberg, Allan René, Sandholt, C. H., Pedersen, Oluf Borbye, Hansen, Torben, Kilpeläinen, Tuomas O., CHARGE Consortium, C. C., Nordestgaard, Børge, Ellervik, Christina, Qi, L. & Mendelian Randomization of Dairy Consumption Working Group, M. R. O. D. C. W. G., 2017, In: The BMJ. 356, 10 p., j1000.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Discovery, characterization, and clinical development of the glucagon-like peptides
Drucker, D. J., Habener, J. F. & Holst, Jens Juul, 1 Dec 2017, In: The Journal of Clinical Investigation. 127, 12, p. 4217-4227 11 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Hepatocyte MyD88 affects bile acids, gut microbiota and metabolome contributing to regulate glucose and lipid metabolism
Duparc, T., Plovier, H., Marrachelli, V. G., Van Hul, M., Essaghir, A., Ståhlman, M., Matamoros, S., Geurts, L., Pardo-Tendero, M. M., Druart, C., Delzenne, N. M., Demoulin, J., van der Merwe, S. W., van Pelt, J., Bäckhed, G. F., Monleon, D., Everard, A. & Cani, P. D., 2017, In: Gut. 66, 4, p. 620-632 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
'No cognitive-enhancing effect of GLP-1 receptor agonism in antipsychotic-treated, obese patients with schizophrenia': authors' response
Ebdrup, Bjørn, Ishøy, P. L., Fagerlund, Birgitte, Broberg, B. V., Bak, N., Knop, Filip Krag & Glenthøj, Birte Yding, Nov 2017, In: Acta Psychiatrica Scandinavica. 136, 5, p. 526-527Research output: Contribution to journal › Comment/debate › Research
- Published
Difference in postprandial GLP-1 response despite similar glucose kinetics after consumption of wheat breads with different particle size in healthy men
Eelderink, C., Noort, M. W. J., Sozer, N., Koehorst, M., Holst, Jens Juul, Deacon, Carolyn F., Rehfeld, Jens Frederik, Poutanen, K., Vonk, R. J., Oudhuis, L. & Priebe, M. G., 2017, In: European Journal of Nutrition. 56, 3, p. 1063-1076 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Histone deacetylase 3 prepares brown adipose tissue for acute thermogenic challenge
Emmett, M. J., Lim, H., Jager, J., Richter, H. J., Adlanmerini, M., Peed, L. C., Briggs, E. R., Steger, D. J., Ma, Tao, Sims, C. A., Baur, J. A., Pei, L., Won, K., Seale, P., Gerhart-Hines, Zach & Lazar, M. A., 2017, In: Nature Genetics. 546, 7659, p. 544-448Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exercise modulates the aortic renin-angiotensin system independently of estrogen therapy in ovariectomized hypertensive rats
Endlich, P. W., Claudio, E. R. G., Lima, L. C. F., Ribeiro Júnior, R. F., Peluso, A. A. B., Stefanon, I., Bissoli, N. S., Lemos, V. S., Santos, R. A. S. D. & Abreu, G. R. D., 2017, In: Peptides.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Homozygous carriers of the TCF7L2 rs7903146 T-allele show altered postprandial response in triglycerides and triglyceride-rich lipoproteins
pjx571, pjx571, Hansen, T. H., Mahendran, Y., Pyl, P., Galijatovic, E. A. A., Jonsson, Anna Elisabet, Gjesing, A., Linneberg, Allan René, Jørgensen, T., Hansen, Torben & drb459, drb459, 21 Feb 2017, In: Scientific Reports. 7, 8 p., 43128.Research output: Contribution to journal › Journal article › Research › peer-review
Most downloads
-
5500
downloads
Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
5253
downloads
Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
4541
downloads
The isoenzyme pattern of LDH does not play a physiological role; except perhaps during fast transitions in energy metabolism
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Latest publications
Determinants of plasma levels of proglucagon and the metabolic impact of glucagon receptor signalling: a UK Biobank study
Research output: Contribution to journal › Journal article › Research › peer-review
The interplay between birth weight and obesity in determining childhood and adolescent cardiometabolic risk
Research output: Contribution to journal › Journal article › Research › peer-review
Targeting postsynaptic glutamate receptor scaffolding proteins PSD-95 and PICK1 for obesity treatment
Research output: Contribution to journal › Journal article › Research › peer-review