- 2018
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A randomized placebo-controlled clinical trial of nicotinamide riboside in obese men: safety, insulin-sensitivity, and lipid-mobilizing effects
Dollerup, O. L., Christensen, B., Svart, M., Schmidt, M. S., Sulek, K., Ringgaard, S., Stødkilde-Jørgensen, H., Møller, N., Brenner, C., Treebak, Jonas Thue & Jessen, N., 2018, In: American Journal of Clinical Nutrition. 108, 2, p. 343-353 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sperm epigenetics and influence of environmental factors
Donkin, I. & Barrès, Romain, 2018, In: Molecular Metabolism. 14, p. 1-11 11 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Human P2Y11 expression level affects human P2X7 receptor-mediated cell death
Dreisig, K., Sund, L., Dommer, M. W., Kristensen, N. P., Boddum, K., Viste, R., Fredholm, S., Ødum, Niels, Jäättelä, M., Skov, Søren & Kornum, Birgitte Rahbek, 2018, In: Frontiers in Immunology. 9, JUN, 12 p., 1159.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Prospective Cohort Study in Patients with Type 2 Diabetes Mellitus for Validation of Biomarkers (PROVALID) - Study Design and Baseline Characteristics
Eder, S., Leierer, J., Kerschbaum, J., Rosivall, L., Wiecek, A., de Zeeuw, D., Mark, P. B., Heinze, G., Rossing, Peter, Heerspink, H. L. & Mayer, G., 2018, In: Kidney and Blood Pressure Research. 43, 1, p. 181-190Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Profiling of G protein-coupled receptors in vagal afferents reveals novel gut-to-brain sensing mechanisms
Egerod, Kristoffer Lihme, Petersen, N., Timshel, P. N., Rekling, Jens Christian, Wang, Y., Liu, Q., Schwartz, Thue W. & Gautron, L., 2018, In: Molecular Metabolism. 12, p. 62-75 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Birth weight variants are associated with variable fetal intrauterine growth from 20 weeks of gestation
pjx571, pjx571, Gybel-brask, D., Mahendran, Y., Crusell, Mie Korslund Wiinblad, Hansen, T. H., Schnurr, T. M., Høgdall, Estrid Vilma Solyom, Skibsted, L., Hansen, Torben & drb459, drb459, 2018, In: Scientific Reports. 8, 11 p., 8376.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Common variants in the hERG (KCNH2) voltage-gated potassium channel are associated with altered fasting and glucose-stimulated plasma incretin and glucagon responses
pjx571, pjx571, Mahendran, Y., Jonsson, Anna Elisabet, Gjesing, A. P., Weeke, P. E., Jørgensen, M. E., Færch, K., Witte, D. R., Holst, Jens Juul, Jørgensen, T., Grarup, N., Pedersen, Oluf Borbye, drb459, drb459, Torekov, Signe Sørensen, Kanters, Jørgen K. & Hansen, Torben, 2018, In: B M C Genetics. 19, 1, p. 1-9 9 p., 15.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exercise training alters the genomic response to acute exercise in human adipose tissue
Fabre, O., Ingerslev, L. R., Garde, C., Donkin, I., Simar, D. & Barrès, Romain, 2018, In: Epigenomics. 10, 8, p. 1033-1050 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Separating "good" from "bad" faecal dysbiosis: evidence from two cross-sectional studies
Farup, P. G., Aasbrenn, M. & Valeur, J., 2018, In: BMC Obesity. 5, 10 p., 30.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries
Feitosa, M. F., Kraja, A. T., Chasman, D. I., Sung, Y. J., Winkler, T. W., Ntalla, I., Guo, X., Franceschini, N., Cheng, C-Y., Sim, X., Vojinovic, D., Marten, J., Musani, S. K., Li, C., Bentley, A. R., Brown, M. R., Schwander, K., Richard, M. A., Noordam, R., Aschard, H. & 31 others, , 2018, In: PLoS ONE. 13, 6, p. 1-36 e0198166.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cohort Profile: Pregnancy And Childhood Epigenetics (PACE) Consortium
Felix, J. F., Joubert, B. R., Baccarelli, A. A., Sharp, G. C., Almqvist, C., Annesi-Maesano, I., Arshad, H., Baïz, N., Bakermans-Kranenburg, M. J., Bakulski, K. M., Binder, E. B., Bouchard, L., Breton, C. V., Brunekreef, B., Brunst, K. J., Burchard, E. G., Bustamante, M., Chatzi, L., Cheng Munthe-Kaas, M., Corpeleijn, E. & 104 others, , 2018, In: International Journal of Epidemiology. 47, 1, p. 22-23u 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Guanylin and uroguanylin mRNA expression is increased following Roux-en-Y gastric bypass, but guanylins do not play a significant role in body weight regulation and glycemic control
Fernandez-Cachon, M. L., Pedersen, S. L., Rigbolt, K. T., Zhang, C., Fabricius, K., Hansen, H. H., Elster, L., Fink, L. N., Schäfer, M., Rhee, N. A., Langholz, E., Wandall, E., Friis, S. U., Vilmann, P., Kristiansen, V. B., Schmidt, C., Schreiter, K., Breitschopf, K., Hübschle, T., Jorsal, T. & 6 others, , Mar 2018, In: Peptides. 101, p. 32-43 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Combination of Fosfomycin, Metronidazole, and Recombinant Human Granulocyte-Macrophage Colony-Stimulating Factor is Stable in vitro and Has Maintained Antibacterial Activity
Fonnes, S., Holzknecht, Barbara Juliane, Gasbjerg, Lærke Smidt, Weisser, J. J., Hallberg, H. W., Arpi, M. & Rosenberg, Jacob, 2018, In: Drug Research. 68, 6, p. 349-354Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Non-insulin pharmacological therapies for treating type 1 diabetes
Frandsen, C. S., Dejgaard, T. F., Madsbad, Sten & Holst, Jens Juul, 2018, In: Expert Opinion on Pharmacotherapy. 19, 9, p. 947-960Research output: Contribution to journal › Review › Research › peer-review
- Published
A Common Allele in FGF21 Associated with Sugar Intake Is Associated with Body Shape, Lower Total Body-Fat Percentage, and Higher Blood Pressure
Frayling, T. M., Beaumont, R. N., Jones, S. E., Yaghootkar, H., Tuke, M. A., Ruth, K. S., Casanova, F., West, B., Locke, J., Sharp, S., Ji, Y., Thompson, W., Harrison, J., Etheridge, A. S., Gallins, P. J., Jima, D., Wright, F., Zhou, Y., Innocenti, F., Lindgren, C. M. & 6 others, , 2018, In: Cell Reports. 23, 2, p. 327-336Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of liraglutide on ectopic fat in polycystic ovary syndrome: A randomized clinical trial
Frøssing, S., Nylander, M., Chabanova, E., Frystyk, J., Holst, Jens Juul, Kistorp, Caroline Michaela Nervil, Skouby, Sven O. & Faber, Jens, Jan 2018, In: Diabetes, Obesity and Metabolism. 20, 1, p. 215-218Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human GIP(3-30)NH inhibits G protein-dependent as well as G protein-independent signaling and is selective for the GIP receptor with high-affinity binding to primate but not rodent GIP receptors
Gabe, M. B. N., Sparre-Ulrich, A. H., Pedersen, M. F., Gasbjerg, Lærke Smidt, Inoue, A., Bräuner, Hans, Hartmann, Bolette & Rosenkilde, M. M., 31 Jan 2018, In: Biochemical Pharmacology. 150, p. 97-107 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Higher chlorzoxazone clearance in obese children compared with nonobese peers
Gade, C., Dalhoff, Kim, Petersen, Tonny Studsgaard, Riis, T., Schmeltz, C., Chabanova, E., Christensen, H. R., Mikus, G., Burhenne, J., Holm, Jens-Christian & Holst, H., 2018, In: British Journal of Clinical Pharmacology. 84, 8, p. 1738-1747 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Succesfuld behandling af KCNJ11-neonatal diabetes uden insulin
Gade-Rasmussen, B., Madsbad, Sten, Svane, M. S., Martinussen, C. & Hansen, Torben, 2018, In: Ugeskrift for Laeger. 180, 46, 2 p., V08180547.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Disruption of glucagon receptor signaling causes hyperaminoacidemia exposing a possible liver-alpha-cell axis
Galsgaard, Katrine Douglas, Winther-Sørensen, Marie, Ørskov, Cathrine, Kissow, Hannelouise, Poulsen, Steen Seier, Vilstrup, H., Prehn, C., Adamski, J., Jepsen, Sara Lind, Hartmann, Bolette, Dal, Jenna Elizabeth Hunt, Charron, M. J., Pedersen, Jens, Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, 2018, In: American Journal of Physiology: Endocrinology and Metabolism. 314, 1, p. E93-E103Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Postprandial effects of individual and combined GIP and GLP-1 receptor antagonism in healthy subjects
Gasbjerg, Lærke Smidt, Helsted, M. M., wbf943, wbf943, Lanng, A. R., Stensen, S., Jakobsen, M. H., Hartmann, Bolette, Christensen, Mikkel Bring, Holst, Jens Juul, Vilsbøll, Tina, Rosenkilde, M. M. & Knop, Filip Krag, 2018, In: Diabetologia. 61, S1, p. S246-S246 503.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
GIP(3-30)NH2 is an efficacious GIP receptor antagonist in humans: a randomised, double-blinded, placebo-controlled, crossover study
Gasbjerg, Lærke Smidt, Christensen, Mikkel Bring, Hartmann, Bolette, Lanng, A. R., wbf943, wbf943, Gabe, M. B. N., Dela, Flemming, Vilsbøll, Tina, Holst, Jens Juul, Rosenkilde, Mette & Knop, Filip Krag, Feb 2018, In: Diabetologia. 61, 2, p. 413-423Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucose-dependent insulinotropic polypeptide (GIP) receptor antagonists as anti-diabetic agents
Gasbjerg, Lærke Smidt, Gabe, M. B. N., Hartmann, Bolette, Christensen, Mikkel Bring, Knop, Filip Krag, Holst, Jens Juul & Rosenkilde, Mette, Feb 2018, In: Peptides. 100, p. 173-181Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Parsing the Potential Neuroendocrine Actions of FGF21 in Primates
Gillum, M. P., 2018, In: Endocrinology. 159, 5, p. 1966-1970 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cohort-wide deep whole genome sequencing and the allelic architecture of complex traits
Gilly, A., Suyeges, D., Kuchenbaecker, K., Pollard, M., Southam, L., Hatzikotoulas, K., Farmaki, A-E., Bjornland, T., Waples, R., Appel, E. V. R., Casalone, E., Melloni, G., Kilian, B., Rayner, N. W., Ntalla, I., Kundu, K., Walter, K., Danesh, J., Butterworth, A., Barroso, I. & 5 others, , 1 Dec 2018, In: Nature Communications. 9, p. 1-9 4674.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Childhood Stature and Growth in Relation to First Ischemic Stroke or Intracerebral Hemorrhage
Gjærde, L. K., Truelsen, T. C. & Baker, J. L., Mar 2018, In: Stroke. 49, 3, p. 579-585Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Squeezing Flux Out of Fat
Gonzalez-Franquesa, A. & Patti, M., 2018, In: Trends in Endocrinology and Metabolism. 29, 4, p. 201-202Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An adult-based insulin resistance genetic risk score associates with insulin resistance, metabolic traits and altered fat distribution in Danish children and adolescents who are overweight or obese
Graae, A. S., Hollensted, M., Kloppenborg, J. T., Mahendran, Y., Schnurr, T. M., Appel, E. V. R., Rask, J., Nielsen, T. R. H., Johansen, M., Linneberg, Allan René, Jørgensen, M. E., Grarup, N., Kadarmideen, H. N., Holst, Birgitte, Pedersen, Oluf Borbye, Holm, Jens-Christian & Hansen, Torben, Aug 2018, In: Diabetologia. 61, 8, p. 1769-1779Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of novel high-impact recessively inherited type 2 diabetes risk variants in the Greenlandic population
Grarup, N., Moltke, Ida, Lepola, Mette Andersen, Bjerregaard, P., Larsen, C. V. L., Dahl-Petersen, I. K., Jørsboe, E., Tiwari, H. K., Hopkins, S. E., Wiener, H. W., Boyer, B. B., Linneberg, Allan René, Pedersen, Oluf Borbye, Jørgensen, M. E., Albrechtsen, Anders & Hansen, Torben, 1 Sep 2018, In: Diabetologia. 61, 9, p. 2005–2015Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Loss-of-function variants in ADCY3 increase risk of obesity and type 2 diabetes
Grarup, N., Moltke, Ida, Lepola, Mette Andersen, Dalby, M., Vitting-Seerup, K., Kern, T. S., Mahendran, Y., Jørsboe, E., Larsen, C. V. L., Dahl-Petersen, I. K., Gilly, A., Suveges, D., Dedoussis, G., Zeggini, E., Pedersen, Oluf Borbye, Andersson, Robin, Bjerregaard, P., Jørgensen, M. E., Albrechtsen, Anders & Hansen, Torben, 2018, In: Nature Genetics. 50, 2, p. 172-174 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of Smoking Versus Nonsmoking on Postprandial Glucose Metabolism in Heavy Smokers Compared With Nonsmokers
Grøndahl, M. F., Bagger, J. I., Lund, A., Faurschou, A., Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, Jun 2018, In: Diabetes Care. 41, 6, p. 1260-1267Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A large-scale RNA interference screen identifies genes that regulate autophagy at different stages
Guo, S., Pridham, K. J., Virbasius, C., He, B., Zhang, L., Varmark, H., Green, M. R. & Sheng, Z., 2018, In: Scientific Reports. 8, 1, p. 1-15 2822.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Population-based studies of relationships between dietary acidity load, insulin resistance and incident diabetes in Danes 11 Medical and Health Sciences 1103 Clinical Sciences
Gæde, J., Nielsen, T., Madsen, M. L., Toft, Ulla Marie Nørgaard, Jørgensen, T., Overvad, K., Tjønneland, Anne, Hansen, Torben, Allin, K. H. & Pedersen, Oluf Borbye, 6 Oct 2018, In: Nutrition Journal. 17, 1, 91.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-Like Peptide-1 Inhibits Prandial Gastrointestinal Motility Through Myenteric Neuronal Mechanisms in Humans
Halim, M. A., Degerblad, M., Sundbom, M., Karlbom, U., Holst, Jens Juul, Webb, D. & Hellstrom, P. M., 2018, In: Journal of Clinical Endocrinology & Metabolism. 103, 2, p. 575-585Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Discovery of a Potent Thiazolidine Free Fatty Acid Receptor 2 Agonist with Favorable Pharmacokinetic Properties
Hansen, A. H., Sergeev, E., Bolognini, D., Sprenger, R. R., Ekberg, J. H., Ejsing, C. S., McKenzie, C. J., Ulven, Elisabeth Rexen, Milligan, G. & Ulven, Trond, 2018, In: Journal of Medicinal Chemistry. 61, 21, p. 9534-9550 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A low-gluten diet induces changes in the intestinal microbiome of healthy Danish adults
Hansen, L. B. S., Roager, H. M., Søndertoft, N. B., Gøbel, R. J., Kristensen, M. B., Vallès-Colomer, M., Vieira-Silva, S., Ibrügger, S., Lind, M. V., Mærkedahl, R. B., Bahl, M. I., Madsen, M. L., Havelund, J., Falony, G., Tetens, I., Nielsen, T., Allin, K. H., Frandsen, H. L., Hartmann, B., Holst, J. J. & 32 others, , 2018, In: Nature Communications. 9, 13 p., 4630.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cancer and Pain
Hansen, R. B. & Falk, S., Nov 2018, The Oxford Handbook of the Neurobiology of Pain. Oxford University PressResearch output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Bone turnover, calcium homeostasis, and vitamin D status in Danish vegans
Hansen, T. H., Madsen, M. T. B., Jørgensen, N. R., Cohen, A. S., Hansen, Torben, drb459, drb459, Pedersen, Oluf Borbye & Allin, K. H., 2018, In: European Journal of Clinical Nutrition. 72, p. 1046-1054 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of a vegan diet on the human salivary microbiota
Hansen, T. H., Kern, T., Bak, Emilie Glad, Kashani, A., Allin, K. H., Nielsen, T., Hansen, Torben & Pedersen, Oluf Borbye, 2018, In: Scientific Reports. 8, p. 1-11 5847.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of drinking water pH on the human gut microbiota and glucose regulation: results of a randomized controlled cross-over intervention
Hansen, T. H., Thomassen, M. T., Madsen, M. L., Kern, T., Bak, Emilie Glad, Kashani, A., Allin, K. H., Hansen, Torben & Pedersen, Oluf Borbye, 2018, In: Scientific Reports. 8, 12 p., 16626.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The association of IgA deficiency on infection rate, self-perceived health, and levels of C-reactive protein in healthy blood donors
Hauge, S. C., Jensen, C. K., Nielsen, L. K., Pedersen, Oluf Borbye, Sørensen, E., Thørner, L. W., Hjalgrim, H., Erikstrup, C., Nielsen, K. R., Kaspersen, K. A., Didriksen, Maria, Dziegiel, Morten Hanefeld & Ullum, H., 1 Mar 2018, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 126, 3, p. 248-256 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The role of the incretins in the postprandial bone remodelling
Helsted, M. M., Gasbjerg, Lærke Smidt, Lanng, A. R., Stensen, S., Hartmann, Bolette, Christensen, Mikkel Bring, Holst, Jens Juul, Vilsbøll, Tina, Rosenkilde, M. M. & Knop, Filip Krag, 2018, In: Diabetologia. 61, S1, p. S221-S221 449.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Single Cell Analysis Identifies the miRNA Expression Profile of a Subpopulation of Muscle Precursor Cells Unique to Humans With Type 2 Diabetes
Henriksen, T. I., Heywood, S. E., Hansen, N. S., Pedersen, Bente Klarlund, Schéele, Camilla Charlotte Nielsen & Nielsen, S., 2018, In: Frontiers in Physiology. 9, p. 1-13 13 p., 883.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In Vitro Community Synergy between Bacterial Soil Isolates Can Be Facilitated by pH Stabilization of the Environment
Herschend, J., Koren, K., Røder, Henriette Lyng, Brejnrod, A., Kühl, Michael & Burmølle, Mette, 2018, In: Applied and Environmental Microbiology. 84, 21, e01450.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In vitro community synergy between bacterial soil isolates can be facilitated by pH stabilisation of the environment.
Herschend, J., Koren, K., Røder, Henriette Lyng, Brejnrod, A. D., Kühl, Michael & Burmølle, Mette, 2018, In: Applied and Environmental Microbiology. 84, 21, p. 1-15 e01450-18.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic Susceptibility for Childhood BMI has no Impact on Weight Loss Following Lifestyle Intervention in Danish Children
Hollensted, M., Fogh, M., Schnurr, T. M., Kloppenborg, J. T., Have, C. T., Nielsen, T. R. H., Rask, J., Lund, Morten Asp Vonsild, Frithioff-Bøjsøe, C., Østergaard Johansen, M., Vincent Rosenbaum Appel, E., Mahendran, Y., Grarup, N., Kadarmideen, H. N., Pedersen, Oluf Borbye, Holm, Jens-Christian & Hansen, Torben, 2018, In: Obesity. 26, 12, p. 1915-1922 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic insights into fetal growth and measures of glycaemic regulation and adiposity in adulthood: a family-based study
Hollensted, M., Ekstrøm, Claus Thorn, Pedersen, Oluf Borbye, Eiberg, Hans Rudolf Lytchoff, Hansen, Torben & Gjesing, A. P., 2018, In: BMC Medical Genetics. 19, p. 1-9 9 p., 207.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Oxyntomodulin: actions and role in diabetes
Holst, Jens Juul, Albrechtsen, Nicolai Jacob Wewer, Gabe, M. B. N. & Rosenkilde, M. M., 2018, In: Peptides. 100, p. 48-53 6 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Erratum to semaglutide seems to be more effective the other GLP-1Ras
Holst, Jens Juul & Madsbad, Sten, 2018, In: Annals of Translational Medicine. 6, 3, p. 74Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mechanisms in bariatric surgery: Gut hormones, diabetes resolution, and weight loss
Holst, Jens Juul, Madsbad, Sten, Bojsen-Møller, K. N., Svane, M. S., Jørgensen, N. B., Dirksen, C. & Martinussen, C., May 2018, In: Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery. 14, 5, p. 708-714 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evidence of genetic predisposition for metabolically healthy obesity and metabolically obese normal weight
Huang, L. O., Loos, Ruth & Kilpeläinen, Tuomas O., 2018, In: Physiological Genomics. 50, 3, p. 169-178 10 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Stimulation of the Bile Acid Receptor Tgr5 Promotes Intestinal Growth
Dal, Jenna Elizabeth Hunt, Hartmann, Bolette, Ullmer, C., Holst, Jens Juul & Kissow, Hannelouise, 1 May 2018, In: Gastroenterology. 154, 6 (S1), 1 p., S-333.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Effect of liraglutide treatment on jejunostomy output in patients with short bowel syndrome: An open-label pilot study
Hvistendahl, M., Brandt, C. F., Tribler, S., Naimi, R. M., Hartmann, Bolette, Holst, Jens Juul, Rehfeld, Jens Frederik, Hornum, Mads, Andersen, Jens Rikardt, Henriksen, B. M., Brøbech Mortensen, P. & Jeppesen, Palle Bekker, 2018, In: Journal of Parenteral and Enteral Nutrition. 42, 1, p. 112-121 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Endogenous glucagon-like peptide- 1 and 2 are essential for regeneration after acute intestinal injury in mice
Hytting-Andreasen, R., Balk-Møller, E., Hartmann, Bolette, Pedersen, Jens, Windeløv, Johanne Agerlin, Holst, Jens Juul & Kissow, Hannelouise, 2018, In: PLoS ONE. 13, 6, p. 1-14 e0198046.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Role of Glucagon in the Pathophysiology and Treatment of Type 2 Diabetes
Hædersdal, S., Lund, A., Knop, Filip Krag & Vilsbøll, Tina, 2018, In: Mayo Clinic Proceedings. 93, 2, p. 217-239Research output: Contribution to journal › Review › Research › peer-review
- Published
Sevoflurane Impairs Insulin Secretion and Tissue-Specific Glucose Uptake In Vivo
Høyer, K. F., Nielsen, Thomas Svava, Risis, S., Treebak, Jonas Thue & Jessen, N., 2018, In: Basic & Clinical Pharmacology & Toxicology. 123, 6, p. 732-738Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Patients with Obesity Caused by Melanocortin-4 Receptor Mutations Can Be Treated with a Glucagon-like Peptide-1 Receptor Agonist
Iepsen, E. W., Zhang, J., Thomsen, Henrik S., Hansen, E. L., Hollensted, M., Madsbad, Sten, Hansen, Torben, Holst, Jens Juul, Holm, Jens-Christian & Torekov, Signe Sørensen, 2018, In: Cell Metabolism. 28, 1, p. 23-32.e3Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gamma-Aminobutyric Acid Signaling in Brown Adipose Tissue Promotes Systemic Metabolic Derangement in Obesity
Ikegami, R., Shimizu, I., Sato, T., Yoshida, Y., Hayashi, Y., Suda, M., Katsuumi, G., Li, J., Wakasugi, T., Minokoshi, Y., Okamoto, S., Hinoi, E., Nielsen, S., Jespersen, N. Z., Schéele, Camilla Charlotte Nielsen, Soga, T. & Minamino, T., 2018, In: Cell Reports. 24, 11, p. 2827-2837.e5 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Endurance training remodels sperm-borne small RNA expression and methylation at neurological gene hotspots
Ingerslev, L. R., Donkin, I., Fabre, O., Versteyhe, S., Mechta, Mie, Pattamaprapanont, P., Mortensen, B., Krarup, N. T. & Barrès, Romain, 2018, In: Clin Epigenetics. 10, 1, p. 1-11 12.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High Blood Eosinophils in Acute Exacerbation of Chronic Obstructive Lung Disease Is Not Associated with Higher Risk of Readmission or Mortality
Jabarkhil, A., Janner, Julie Hjortsø, Moberg, M., Eriksen, N., Pedersen, M. N., Jensen, C. B., Ängquist, Lars, Vestbo, J., Jess, T. & Porsbjerg, Celeste Michala, 2018, In: American Journal of Respiratory and Critical Care Medicine. 197, 1 p., A3123.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Meta-analysis of exome array data identifies six novel genetic loci for lung function
Jackson, V. E., Latourelle, J. C., Wain, L. V., Smith, A. V., Grove, M. L., Bartz, T. M., Obeidat, M., Province, M. A., Gao, W., Qaiser, B., Porteous, D. J., Cassano, P. A., Ahluwalia, T. S., Grarup, N., Li, J., Altmaier, E., Marten, J., Harris, S. E., Manichaikul, A., Pottinger, T. D. & 31 others, , 2018, In: Wellcome Open Research. 3, p. 1-28Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Associations between birth size and later height from infancy through adulthood: An individual based pooled analysis of 28 twin cohorts participating in the CODATwins project
Jelenkovic, A., Yokoyama, Y., Sund, R., Hur, Y-M., Harris, J. R., Brandt, I., Nilsen, T. S., Ooki, S., Ullemar, V., Almqvist, C., Magnusson, P. K. E., Saudino, K. J., Stazi, M. A., Fagnani, C., Brescianini, S., Nelson, T. L., Whitfield, K. E., Knafo-Noam, A., Mankuta, D., Abramson, L. & 31 others, , 2018, In: Early Human Development. 120, p. 53-60 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Birth size and gestational age in opposite-sex twins as compared to same-sex twins: An individual-based pooled analysis of 21 cohorts
Jelenkovic, A., Sund, R., Yokoyama, Y., Hur, Y-M., Ullemar, V., Almqvist, C., Magnusson, P. K. E., Willemsen, G., Bartels, M., van Beijsterveldt, C. E. M., Bogl, L. H., Pietilainen, K. H., Vuoksimaa, E., Ji, F., Ning, F., Pang, Z., Nelson, T. L., Whitfield, K. E., Rebato, E., Llewellyn, C. H. & 38 others, , 1 Dec 2018, In: Scientific Reports. 8, 1, p. 1-8 8 p., 6300.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increase in clinically recorded type 2 diabetes after colectomy
Jensen, A. B., Sørensen, Thorkild I.A., Pedersen, Oluf Borbye, Jess, T., Brunak, Søren & Allin, K. H., 2018, In: eLife. 7, e37420.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Change in weight status from childhood to early adulthood and late adulthood risk of colon cancer in men: a population-based cohort study
Jensen, B. W., Bjerregaard, L. G., Ängquist, Lars, Gögenur, Ismail, Renehan, A. G., Osler, Merete, Sørensen, Thorkild I.A. & Baker, J. L., 1 Oct 2018, In: International Journal of Obesity. 42, p. 1797-1803 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Childhood body mass index and risk of inflammatory bowel disease in adulthood: a population-based cohort study
Jensen, C. B., Ängquist, Lars, Mendall, M. A., Sørensen, Thorkild I.A., Baker, J. L. & Jess, T., 2018, In: The American Journal of Gastroenterology. 113, 5, p. 694-701 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
RCR - A Danish textbook for courses in Responsible Conduct of Research
Jensen, Karsten Klint (ed.), Whiteley, Louise (ed.) & Sandøe, Peter (ed.), Jan 2018, 3 ed. Frederiksberg: Department of Food and Resource Economics, University of Copenhagen. 115 p.Research output: Book/Report › Book › Education
- Published
Stone Age “chewing gum” yields 5,700 yearold human genome and oral microbiome
Jensen, Theis Zetner Trolle, Niemann, Jonas, Iversen, K. H., Fotaki, Anna Katerina, Gopalakrishan, S., Sinding, Mikkel Holger Strander, Ellegaard, M. R., Allentoft, Morten Erik, Lanigan, Liam Thomas, Taurozzi, Alberto John, Nielsen, Sofie Holtsmark, Dee, M. W., Mortensen, M. N., Christensen, M. C., Sørensen, S. A., Collins, Matthew James, Gilbert, M Thomas P, Sikora, Martin, Rasmussen, Simon & Schroeder, Hannes, 2018, bioRxiv, 32 p.Research output: Working paper › Preprint › Research
- Published
Protocol for Meal-time Administration of Exenatide for Glycaemic Control in Type 1 Diabetes Cases (The MAG1C trial): A randomised, double-blinded, placebo-controlled trial
Johansen, N. J., Dejgaard, T. F., Lund, A., Vilsbøll, Tina, Andersen, H. U. & Knop, Filip Krag, 2018, In: BMJ Open. 8, 6, 8 p., 021861.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of Gut Microbiota and Diet on the Development of Atherosclerosis in Apoe-/- Mice
Jonsson, A. L., Caesar, R., Akrami, R., Reinhardt, C., Hallenius, F. F., Boren, J. & Baeckhed, F., 2018, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 38, 10, p. 2318-2326 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Enteroendocrine K and L cells in healthy and type 2 diabetic individuals
Jorsal, T., Rhee, N. A., Pedersen, Jens, Wahlgren, C. D., Mortensen, B., Jepsen, Sara Lind, Jelsing, J., Dalbøge, L. S., Vilmann, Peter, Hassan, H., Hendel, J. W., Poulsen, Steen Seier, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 1 Feb 2018, In: Diabetologia. 61, 2, p. 284-294 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hidradenitis suppurativa and electrocardiographic changes: a cross‐sectional population study
Juhl, C. R., Miller, I. M., Jemec, Gregor, Kanters, Jørgen K. & Ellervik, Christina, Jan 2018, In: British Journal of Dermatology. 178, 1, p. 222-228Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dairy Intake and Acne Vulgaris: A Systematic Review and Meta-Analysis of 78,529 Children, Adolescents, and Young Adults
Juhl, C. R., Bergholdt, H. K. M., Miller, I. M., Jemec, Gregor, Kanters, Jørgen K. & Ellervik, Christina, 9 Aug 2018, In: Nutrients. 10, 8, 13 p., 1049.Research output: Contribution to journal › Review › Research › peer-review
- Published
Lactase Persistence, Milk Intake, and Adult Acne: A Mendelian Randomization Study of 20,416 Danish Adults
Juhl, C. R., Bergholdt, H. K. M., Miller, I. M., Jemec, Gregor, Kanters, Jørgen K. & Ellervik, Christina, 8 Aug 2018, In: Nutrients. 10, 8, 11 p., 1041.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The complement system is differently regulated in white and brown adipocytes
Justesen, L., Bayarri-Olmos, R., Schéele, Camilla Charlotte Nielsen & Garred, Peter, 2018, In: Molecular Immunology. 102, p. 170 1 p.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Neurog3-dependent pancreas dysgenesis causes ectopic pancreas in Hes1 mutant mice
Jørgensen, Mette Christine, de Lichtenberg, K. H., Collin, C. A., Klinck, R., Ekberg, J. H., Engelstoft, M. S., Lickert, H. & Serup, Palle, Sep 2018, In: Development (Cambridge, England). 145, 17, p. 1-11 11 p., dev163568.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Breastfeeding and later maternal risk of hypertension and cardiovascular disease - The role of overall and abdominal obesity
Kirkegaard, H., Bliddal, M., Stovring, H., Rasmussen, K. M., Gunderson, E. P., Køber, Lars Valeur, Sørensen, Thorkild I.A. & Nohr, E. A., 2018, In: Preventive Medicine. 114, p. 140-148 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exploring mucosal function as a clinical endpoint in ulcerative colitis
Kjaergaard, S., Damm, M. M. B., Chang, J., Riis, Lene Buhl, Hytting-Andreasen, R., Krug, S. M., Schulzke, J. D., Bindslev, Niels & Hansen, Morten Bagge, 2018, In: Journal of Crohn's and Colitis. 12, S1, p. S169-S169 P145 .Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Indicator of RNA oxidation in urine for the prediction of mortality in patients with type 2 diabetes and microalbuminuria: a post-hoc analysis of the Steno-2 trial
Kjær, L. K., Oellgaard, J., Henriksen, T., Gaede, P., Pedersen, Oluf Borbye & Poulsen, Henrik Enghusen, 2018, In: Free Radical Biology and Medicine. 129, p. 247-255Research output: Contribution to journal › Journal article › Research › peer-review
- Published
AMPK in skeletal muscle function and metabolism
Kjøbsted, Rasmus, Hingst, J. R., Fentz, J., Foretz, M., Sanz, M., Pehmøller, C., Shum, M., Marette, A., Mounier, R., Treebak, Jonas Thue, Wojtaszewski, Jørgen F P, Viollet, B. & Lantier, L., 2018, In: F A S E B Journal. 32, 4, p. 1741-1777 37 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Exercise increases circulating GDF15 in humans
Kleinert, Maximilian, Clemmensen, Christoffer, Sjøberg, K. A., Carl, Christian Strini, Jeppesen, J. F., Wojtaszewski, Jørgen F P, Kiens, Bente & Richter, Erik A., 2018, In: Molecular Metabolism. 9, p. 187-191 5 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Time-resolved hypothalamic open flow micro-perfusion reveals normal leptin transport across the blood–brain barrier in leptin resistant mice
Kleinert, Maximilian, Kotzbeck, P., Altendorfer-Kroath, T., Birngruber, T., Tschöp, M. H. & Clemmensen, Christoffer, 2018, In: Molecular Metabolism. 13, p. 77-82 6 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Impaired fasting glucose and the metabolic profile in Danish children and adolescents with normal weight, overweight, or obesity
Kloppenborg, J. T., Fonvig, Cilius Esmann, Nielsen, T. R. H., Mollerup, P. M., Bøjsøe, C., Pedersen, Oluf Borbye, Johannesen, Jesper, Hansen, Torben & Holm, Jens-Christian, May 2018, In: Pediatric Diabetes. 19, 3, p. 356-365Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of impaired glucose metabolism on weight loss in multidisciplinary childhood obesity treatment
Kloppenborg, J. T., Gamborg, Michael Orland, Fonvig, Cilius Esmann, Nielsen, T. R. H., Pedersen, Oluf Borbye, Johannesen, Jesper, Hansen, Torben & Holm, Jens-Christian, 2018, In: Pediatric Diabetes. 19, 3, p. 366-374 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A gut feeling about glucagon: Eje Prize 2018
Knop, Filip Krag, 2018, In: European Journal of Endocrinology. 178, 6, p. R267-R280 14 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Microbially Produced Imidazole Propionate Impairs Insulin Signaling through mTORC1
Koh, A., Molinaro, A., Stahlman, M., Khan, M. T., Schmidt, C., Manneras-Holm, L., Wu, H., Carreras, A., Jeong, H., Olofsson, L. E., Bergh, P., Gerdes, V., Hartstra, A., de Brauw, M., Perkins, R., Nieuwdorp, M., Bergstrom, G. & Backhed, F., 2018, In: Cell. 175, 4, p. 947-961.e17Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Incretin responses to oral glucose and mixed meal tests and changes in fasting glucose levels during 7 years of follow-up: The Hoorn Meal Study
Koopman, A. D. M., Rutters, F., Rauh, S. P., Nijpels, G., Holst, Jens Juul, Beulens, J. W., Alssema, M. & Dekker, J. M., 2018, In: PloS one. 13, 1, 13 p., e0191114.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pleiotropic Effects of Heparins: From Clinical Applications to Molecular Mechanisms in Hepatocellular Carcinoma
Korhan, P., Yılmaz, Y., Bağırsakçı, E., Güneş, A., Topel, Hande, Carr, B. I. & Atabey, N., 2018, In: Canadian Journal of Gastroenterology. 2018, p. 7568742Research output: Contribution to journal › Review › Research › peer-review
- Published
Hypertension genetic risk score is associated with burden of coronary heart disease among patients referred for coronary angiography
Krogager, M. L., Skals, R. K., Appel, E. V. R., Schnurr, T. M., pjx571, pjx571, Have, C. T., Pedersen, Oluf Borbye, Engstrøm, Thomas, Roden, D. M., Gislason, Gunnar Hilmar, Poulsen, Henrik Enghusen, Køber, Lars Valeur, Stender, Steen, Hansen, Torben, Grarup, N., Andersson, C., Torp-Pedersen, Christian & Weeke, P. E., 2018, In: P L o S One. 13, 12, p. 1-17 e0208645.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Assessing Rare Variation in Complex Traits
Kuchenbaecker, K. & Appel, E. V. R., 2018, Genetic Epidemiology: Methods and Protocols. Evangelou, E. (ed.). Springer, p. 51-71 (Methods in Molecular Biology, Vol. 1793).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Bile acids are important direct and indirect regulators of the secretion of appetite- and metabolism-regulating hormones from the gut and pancreas.
Kuhre, Rune Ehrenreich, Albrechtsen, Nicolai Jacob Wewer, Larsen, Olav, Jepsen, Sara Lind, Balk-Møller, E., Andersen, Daniel Bjørklund, Deacon, Carolyn F., Schoonjans, K., Reimann, F., Gribble, F. M., Albrechtsen, Reidar, Hartmann, Bolette, Rosenkilde, Mette & Holst, Jens Juul, 2018, In: Molecular Metabolism. 11, p. 84-95 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gut microbiota dysbiosis is associated with malnutrition and reduced plasma amino acid levels: Lessons from genome-scale metabolic modeling
Kumar, M., Ji, B., Babaei, P., Das, P., Lappa, D., Ramakrishnan, G., Fox, T. E., Haque, R., Petri, W. A., Backhed, F. & Nielsen, J., 2018, In: Metabolic Engineering. 49, p. 128-142Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Spatial QRS-T angle variants for prediction of all-cause mortality
Kück, K., Isaksen, Jonas L., Graff, C., Skaaby, T., Linneberg, Allan René, Hansen, Torben & Kanters, Jørgen K., 2018, In: Journal of Electrocardiology. 51, 5, p. 768-775 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Effect of Ethanol on Inflammation Markers and FGF-21 in Healthy Individuals
Lanng, A. R., Gasbjerg, Lærke Smidt, Bergmann, N. C., Møller, H., Gillum, M., Gronbaek, H., Vilsbøll, Tina & Knop, Filip Krag, 2018, In: Diabetes. 67, Supplement 1, 2415-PUB.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
FAK tyrosine phosphorylation is regulated by AMPK and controls metabolism in human skeletal muscle
Lassiter, D. G., Nylén, C., Sjögren, R. J. O., Chibalin, A. V., Wallberg-Henriksson, H., Näslund, E., Krook, A. & Zierath, Juleen R, 2018, In: Diabetologia. 61, 2, p. 424-432 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
AMPK activation negatively regulates GDAP1, which influences metabolic processes and circadian gene expression in skeletal muscle
Lassiter, D. G., Sjogren, R. J. O., Gabriel, B. M., Krook, A. & Zierath, Juleen R, 2018, In: Molecular Metabolism. 16, p. 12-23Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Adaptive changes in pancreas post Roux-en-Y gastric bypass induced weight loss
Lautenbach, A., Wernecke, M., Riedel, N., Veigel, J., Yamamura, J., Keller, S., Jung, R., Busch, P., Mann, O., Knop, Filip Krag, Holst, Jens Juul, Meier, J. J. & Aberle, J., Oct 2018, In: Diabetes - Metabolism: Research and Reviews (Print Edition). 34, 7, p. 1-8 e3025.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals
Lee, J. J., Wedow, R., Okbay, A., Kong, E., Maghzian, O., Zacher, M., Tuan Anh Nguyen-Viet, Bowers, P., Sidorenko, J., Linner, R. K., Fontana, M. A., Kundu, T., Lee, C., Li, H., Li, R., Royer, R., Timshel, P. N., Walters, R. K., Willoughby, E. A., Yengo, L. & 58 others, , 2018, In: Nature Genetics. 50, 8, p. 1112-+Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interleukin-6 Delays Gastric Emptying in Humans with Direct Effects on Glycemic Control
Lehrskov, L. L., Lyngbaek, M. P., Soederlund, L., Legaard, G. E., Ehses, J. A., Heywood, S. E., Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Karstoft, K., Pedersen, Bente Klarlund & Ellingsgaard, H., 2018, In: Cell Metabolism. 27, 6, p. 1201-1211Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Systems signatures reveal unique remission-path of Type 2 diabetes following Roux-en-Y gastric bypass surgery
Li, Q-R., Wang, Z-M., Albrechtsen, N. J. W., Wang, D-D., Su, Z-D., Gao, X-F., Wu, Q-Q., Zhang, H-P., Zhu, L., Li, R-X., Jacobsen, S., Jørgensen, N. B., Dirksen, C., Bojsen-Møller, K. N., Petersen, J. S., Madsbad, S., Clausen, T. R., Diderichsen, B., Chen, L-N., Holst, J. J. & 2 others, , 2018, In: EBioMedicine. 28, p. 234-240 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
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Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets
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The isoenzyme pattern of LDH does not play a physiological role; except perhaps during fast transitions in energy metabolism
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