- 2018
- Published
Papio spp. Colon microbiome and its link to obesity in pregnancy
Li, Xuan Ji, Rensing, C., Taylor, W. L., Costelle, C., Brejnrod, A. D., Ferry, R. J. ,. J., Higgins, P. B., Folli, F., Kottapalli, K. R., Hubbard, G. B., Dick, E. J. ,. J., Yooseph, S., Nelson, K. E. & Schlabritz-Loutsevitch, N., Dec 2018, In: Journal of Medical Primatology. 47, 6, p. 393-401Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders
Ligthart, S., Vaez, A., Vosa, U., Stathopoulou, M. G., de Vries, P. S., Prins, B. P., Van der Most, P. J., Tanaka, T., Naderi, E., Rose, L. M., Wu, Y., Karlsson, R., Barbalic, M., Lin, H., Pool, R., Zhu, G., Mace, A., Sidore, C., Trompet, S., Mangino, M. & 266 others, , 1 Nov 2018, In: American Journal of Human Genetics. 103, 5, p. 691-706Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Common and Rare Coding Genetic Variation Underlying the Electrocardiographic PR Interval
Lin, H., van Setten, J., Smith, A. V., Bihlmeyer, N. A., Warren, H. R., Brody, J. A., Radmanesh, F., Hall, L., Grarup, N., Müller-Nurasyid, M., Boutin, T., Verweij, N., Lin, H. J., Li-Gao, R., van den Berg, M. E., Marten, J., Weiss, S., Prins, B. P., Haessler, J., Lyytikäinen, L-P. & 81 others, , 2018, In: Circulation. Genomic and precision medicine. 11, 5, p. 1-11 e002037.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Elucidation of the intrinsic optical properties of hydrogen-bonded and protonated flavin chromophores by photodissociation action spectroscopy
Lincke, K., Langeland, J., Madsen, A. Ø., Kiefer, H. V., Skov, L., Gruber, E., Mikkelsen, Kurt Valentin, Andersen, L. H. & Nielsen, Mogens Brøndsted, 2018, In: Physical Chemistry Chemical Physics. 20, 45, p. 28678-28684 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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One-carbon metabolism markers are associated with cardiometabolic risk factors
Lind, M. V., Lauritzen, Lotte, drb459, drb459, Hansen, Torben, Pedersen, Oluf Borbye, Kristensen, M. B. & Ross, A. B., 2018, In: Nutrition, Metabolism & Cardiovascular Diseases. 28, 4, p. 402-410 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Predicting albuminuria response to spironolactone treatment with urinary proteomics in patients with type 2 diabetes and hypertension
Lindhardt, M., Persson, F., Oxlund, C., Jacobsen, I. A., Zürbig, P., Mischak, H., Rossing, Peter & Heerspink, H. J. L., Feb 2018, In: Nephrology, Dialysis, Transplantation. 33, 2, p. 296-303 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Uncovering the anatomical and molecular landscape of the developing entorhinal cortex.
Liu, Y., Bergmann, T. B., Peralvo Vidal, Juan Miguel, Lee, J., Mori, Yuki, Seemann, Ernst Stefan, Pihl, M., Thomsen, Preben Dybdahl, Gorodkin, Jan, Hyttel, P., Pers, Tune H, witter, M. & Hall, Vanessa Jane, 2018.Research output: Contribution to conference › Conference abstract for conference › Research
- Published
Genes that make you fat, but keep you healthy
Loos, Ruth & Kilpeläinen, Tuomas O., 2018, In: Journal of Internal Medicine. 284, 5, p. 450-463 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhibitor-Induced Conformational Changes in ASIC1A
Lund, Camilla, Borg, C. B., Lynagh, T. & Pless, Stephan, 2 Feb 2018, p. 130A-130A.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
- Published
Brown fat: the biological furnace that could burn away obesity
Lund, Jens, Peics, J. & Gerhart-Hines, Zach, 2018, In: Biozoom. 20, 3, p. 4-6 3 p.Research output: Contribution to journal › Journal article › Research
- Published
Enterochromaffin 5-HT cells - A major target for GLP-1 and gut microbial metabolites
Lund, M. L., Egerod, Kristoffer Lihme, Engelstoft, M. S., Dmytriyeva, O., Theodorsson, E., Patel, B. A. & Schwartz, Thue W., 2018, In: Molecular Metabolism. 11, p. 70-83 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cold-Activated Lipid Dynamics in Adipose Tissue Highlights a Role for Cardiolipin in Thermogenic Metabolism
Lynes, M. D., Shamsi, F., Sustarsic, E. G., Leiria, L. O., Wang, C. H., Su, S. C., Huang, T. L., Gao, Fei, Narain, N. R., Chen, E. Y., Cypess, A. M., Schulz, T. J., Gerhart-Hines, Zach, Kiebish, M. A. & Tseng, Y. H., 2018, In: Cell Reports. 24, 3, p. 781-790 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Individual and combined glucose-lowering effects of glucagon receptor antagonism and dipeptidyl peptidase-4 inhibition
Maagensen, H., Haedersdal, S., Lund, A., Nielsen-Hannerup, E., Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 2018, In: Diabetologia. 61, p. S246-S247Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Treatment with GLP-1 Receptor Agonists
Madsbad, Sten & Holst, Jens Juul, 2018, Diabetes: Epidemiology, Genetics, Pathogenesis, Diagnosis, Prevention, and Treatment. Bonora, E. & DeFronzo, R. (eds.). Springer, 45 p. (Endocrinology).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
The role of the bacterial microbiota in alcoholic and non-alcoholic fatty liver disease
Madsen, Anne Lundager, Brach, Thorsten, Kern, T., Bak, Emilie Glad, Nielsen, T. & Arumugam, Mani, 9 Nov 2018, The Human Gut-Liver-Axis in Health and Disease. Springer, p. 89-104 16 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Education
- Published
Antifibrotic and molecular aspects of rifaximin in alcoholic liver disease: study protocol for a randomized controlled trial
Madsen, B. S., Trebicka, J., Thiele, M., Israelsen, M., Arumugam, Mani, Havelund, T. & Krag, A., 2018, In: Trials. 19, p. 1-5 5 p., 143.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evolutionary conservation of the allosteric activation of factor VIIa by tissue factor in lamprey: comment
Madsen, J. J., Persson, E. & Olsen, O. H., 2018, In: Journal of Thrombosis and Haemostasis. 16, 7, p. 1450-1454Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Genome-wide association analyses identify 39 new susceptibility loci for diverticular disease
Maguire, L. H., Handelman, S. K., Du, X., Chen, Y., Pers, Tune H & Speliotes, E. K., 2018, In: Nature Genetics. 50, 10, p. 1359-1365Research output: Contribution to journal › Letter › Research › peer-review
- Published
Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps
Mahajan, A., Taliun, D., Thurner, M., Robertson, N. R., Torres, J. M., Rayner, N. W., Payne, A. J., Steinthorsdottir, V., Scott, R. A., Grarup, N., Cook, J. P., Schmidt, E. M., Wuttke, M., Sarnowski, C., Magill, R., Nano, J., Gieger, C., Trompet, S., Lecoeur, C., Preuss, M. H. & 95 others, , 2018, In: Nature Genetics. 50, 11, p. 1505-1513Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes
Mahajan, A., Wessel, J., Willems, S. M., Zhao, W., Robertson, N. R., Chu, A. Y., Gan, W., Kitajima, H., Taliun, D., Rayner, N. W., Guo, X., Lu, Y., Li, M., Jensen, R. A., Hu, Y., Huo, S., Lohman, K. K., Zhang, W., Cook, J. P., Prins, B. P. & 32 others, , Apr 2018, In: Nature Genetics. 50, 4, p. 559-571 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Impact of Dietary Fiber on Gut Microbiota in Host Health and Disease
Makki, K., Deehan, E. C., Walter, J. & Backhed, F., 2018, In: Cell Host & Microbe. 23, 6, p. 705-715Research output: Contribution to journal › Review › Research › peer-review
- Published
Comparing olive oil and C4-dietary oil, a prodrug for the GPR119 agonist, 2-oleoyl glycerol, less energy intake of the latter is needed to stimulate incretin hormone secretion in overweight subjects with type 2 diabetes
Mandøe, M. J., Hansen, K. B., Windeløv, Johanne Agerlin, Knop, Filip Krag, Rehfeld, Jens Frederik, Rosenkilde, Mette, Holst, Jens Juul & Hansen, Harald S., 2018, In: Nutrition and Diabetes. 8, 1, p. 1-10 2.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GSK3 is a negative regulator of the thermogenic program in brown adipocytes
Markussen, L. K., Winther, Sally, Wicksteed, B. & Hansen, Jacob B., 2018, In: Scientific Reports. 8, p. 1-12 3469.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
L cell secretory responses after gastric bypass surgery can be imitated in un-operated individuals by modulating carbohydrate digestion
Martinussen, C., Bojsen-Moller, K. N., Dirksen, C., Svane, M. S., Holst, Jens Juul & Madsbad, Sten, 2018, In: Diabetologia. 61, S1, p. S124-S125 244.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Benchmarking the HLA typing performance of Polysolver and Optitype in 50 Danish parental trios
Matey-Hernandez, M. L., Danish Pan Genome Consortium, D. P. G. C., Brunak, Søren, Izarzugaza, J. M. G., Sørensen, L. M., Petersen, Bent, Sibbesen, Jonas Andreas, Liu, S., Belling, K. G., Have, C. T., Bork-Jensen, J., Sun, J., Hansen, Torben, Krogh, Anders, Sørensen, Thorkild I.A., Pedersen, Oluf Borbye, Wang, J., Eiberg, Hans Rudolf Lytchoff & Kristiansen, Karsten, 2018, In: BMC Bioinformatics. 19, p. 1-12 239.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Methodology for Accurate Detection of Mitochondrial DNA Methylation
Mechta, Mie, Ingerslev, L. R. & Barrès, Romain, 2018, In: Journal of Visualized Experiments. 135, e57772.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Translating biased signaling in the ghrelin receptor system into differential in vivo functions
Mende, F., Johnsen, Cecilie Hundahl, Plouffe, B., Skov, Louise Julie, Sivertsen, B., Madsen, A. N., Lückmann, Michael, Diep, T. A., Offermanns, S., Frimurer, Thomas Michael, Bouvier, M. & Holst, Birgitte, 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 43, p. E10255-E10264 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
No changes in levels of bone formation and resorption markers following a broad-spectrum antibiotic course
Mikkelsen, K. H., Vilsbøll, Tina, Holst, Jens Juul, Hartmann, Bolette, Knop, Filip Krag & Frost, M., 2018, In: BMC Endocrine Disorders. 18, 6 p., 60.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structural changes at the myrtenol backbone reverse its positive allosteric potential into inhibitory GABAA receptor modulation
Milanos, S., Kuenzel, K., Gilbert, D. F., Janzen, D., Sasi, M., Buettner, A., Frimurer, Thomas Michael & Villmann, C., 2018, In: Biological Chemistry. 399, 6, p. 549-563 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Specific synbiotics in early life protect against diet-induced obesity in adult mice
Mischke, M., Arora, Tulika, Tims, S., Engels, E., Sommer, N., van Limpt, K., Baars, A., Oozeer, R., Oosting, A., Bäckhed, F. & Knol, J., 2018, In: Diabetes, Obesity and Metabolism. 20, 6, p. 1408-1418 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Metabolite ratios as potential biomarkers for type 2 diabetes: a DIRECT study
Molnos, S., Wahl, S., Haid, M., Eekhoff, E. M. W., Pool, R., Floegel, A., Deelen, J., Much, D., Prehn, C., Breier, M., Draisma, H. H., van Leeuwen, N., Simonis-Bik, A. M. C., Jonsson, A., Willemsen, G., Bernigau, W., Wang-Sattler, R., Suhre, K., Peters, A., Thorand, B. & 24 others, , 2018, In: Diabetologia. 61, 1, p. 117-129 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Breastfeeding and complementary feeding in relation to body mass index and overweight at ages 7 and 11 y: A path analysis within the Danish National Birth Cohort
Morgen, C. S., Ängquist, Lars, Baker, J. L., Nybo Andersen, Anne-Marie, Sørensen, Thorkild I.A. & Michaelsen, Kim F., 2018, In: American Journal of Clinical Nutrition. 107, 3, p. 313-322 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prenatal risk factors influencing childhood BMI and overweight independent of birth weight and infancy BMI: a path analysis within the Danish National Birth Cohort
Morgen, C. S., Ängquist, Lars, Baker, J. L., Andersen, A., Michaelsen, Kim F. & Sørensen, Thorkild I.A., 1 Apr 2018, In: International Journal of Obesity. 42, 4, p. 594-602 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Divergent effects of resistance and endurance exercise on plasma bile acids, FGF19, and FGF21 in humans
Morville, T., Sahl, Ronni Eg, Trammell, Sam, Svenningsen, J. S., Gillum, M. P., Helge, Jørn Wulff & Clemmensen, Christoffer, 2018, In: JCI Insight. 3, 15, p. 1-13 e122737.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gut: a key player in the pathogenesis of type 2 diabetes?
Muscogiuri, G., Balercia, G., Barrea, L., Cignarelli, A., Giorgino, F., Holst, Jens Juul, Laudisio, D., Orio, F., Tirabassi, G. & Colao, A., 2018, In: Critical Reviews in Food Science and Nutrition. 58, 8, p. 1294–1309Research output: Contribution to journal › Review › Research › peer-review
- Published
In vivo and ex vivo inflammatory markers of common metabolic phenotypes in humans
Mærkedahl, R. B., Frøkiær, Hanne, Stenbæk, M. G., Nielsen, C. B., Lind, M. V., Lundtoft, C., Bohr, M. B., Ibrügger, S., Metzdorff, S. B., drb459, drb459, Pedersen, Oluf Borbye & Lauritzen, Lotte, 2018, In: Metabolic Syndrome and Related Disorders. 16, 1, p. 29-39 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Anti-Obesity Therapy: from Rainbow Pills to Polyagonists.
Müller, T., Clemmensen, Christoffer, Finan, B., DiMarchi, R. & Tschöp, M., Oct 2018, In: Pharmacological Reviews.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantitative perfusion assessment of intestinal anastomoses in pigs treated with glucagon-like peptide 2
Nerup, N., Ring, L. L., Strandby, R. B., Egeland, C., Svendsen, M. B. S., Hasselby, Jane Preuss, Willemoe, G. L., Hartmann, Bolette, Svendsen, Lars Bo & Achiam, Michael Patrick, 2018, In: Langenbeck's Archives of Surgery. 403, 7, p. 881-889Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Age at first birth in women is genetically associated with increased risk of schizophrenia
Ni, G., Gratten, J., Wray, N. R., Lee, S. H., Ripke, S., Neale, B. M., Corvin, A., Walters, J. T. R., Farh, K. H., Holmans, P. A., Lee, P., Bulik-Sullivan, B., Collier, D. A., Huang, H., Pers, T. H., Agartz, I., Agerbo, E., Albus, M., Alexander, M., Amin, F. & 281 others, , 2018, In: Scientific Reports. 8, 1, p. 1-14 10168.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of novel LEPR mutations in Pakistani families with morbid childhood obesity
Niazi, R. K., Gjesing, A. P., Hollensted, M., Have, C. T., Grarup, N., Pedersen, Oluf Borbye, Ullah, A., Shahid, G., Ahmad, W., Gul, A. & Hansen, Torben, 2018, In: BMC Medical Genetics. 19, 1, p. 1-8 199.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of diaries written by relatives for intensive care patients on posttraumatic stress (DRIP study): protocol for a randomized controlled trial and mixed methods study
Nielsen, A. H., Angel, S., Egerod, Ingrid Eugenie & Hansen, Torben, 2018, In: BMC Nursing. 17, p. 1-10 10 p., 37.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
NAMPT-mediated NAD+ biosynthesis is indispensable for adipose tissue plasticity and development of obesity
Nielsen, K. N., Peics, J., Ma, Tao, Karavaeva, Iuliia, Dall, M., Chubanava, Sabina, Basse, A. L., Dmytriyeva, O., Treebak, Jonas Thue & Gerhart-Hines, Zach, May 2018, In: Molecular Metabolism. 11, p. 178-188 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hepatitis B virus upregulates host microRNAs that target apoptosis-regulatory genes in an in vitro cell model
Nielsen, K. O., Jacobsen, K. S., Mirza, A. H., Winther, T. N., Størling, J., Glebe, D., Pociot, Flemming & Høgh, Birthe, 2018, In: Experimental Cell Research. 371, 1, p. 92-103Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Childhood obesity treatment; Effects on BMI SDS, body composition, and fasting plasma lipid concentrations
Nielsen, T. R. H., Fonvig, Cilius Esmann, Dahl, M., Mollerup, P. M., Lausten-Thomsen, U., Pedersen, Oluf Borbye, Hansen, Torben & Holm, Jens-Christian, 2018, In: P L o S One. 13, 2, p. 1-18 18 p., e0190576.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lactobacillus reuteri reduces bone loss in older women with low bone mineral density: a randomized, placebo-controlled, double-blind, clinical trial
Nilsson, A. G., Sundh, D., Backhed, F. & Lorentzon, M., 2018, In: Journal of Internal Medicine. 284, 3, p. 307-317Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of DPP-4 protected GLP-1 (7-36) on coronary microcirculation in obese adults
Nilsson, M., Bove, K., Suhrs, E., Hermann, T., Madsbad, Sten, Holst, Jens Juul, Prescott, Eva & Zander, M., 2018, In: Diabetologia. 61, S1, p. S354-S355 729.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
The effect of metformin versus placebo in combination with insulin analogues on bone mineral density and trabecular bone score in patients with type 2 diabetes mellitus: a randomized placebo-controlled trial
Nordklint, A. K., Almdal, Thomas Peter, Vestergaard, P., Lundby-Christensen, L., Boesgaard, T. W., Breum, Leif, Gade-Rasmussen, B., Sneppen, S. B., Gluud, C., Hemmingsen, B., Jensen, T., Krarup, T., Madsbad, Sten, Mathiesen, Elisabeth, Perrild, Hans, Tarnow, L., Thorsteinsson, B., drb459, drb459, Lund, S. S. & Eiken, P., 2018, In: Osteoporosis International. 29, 11, p. 2517-2526Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Soil bacteria show different tolerance ranges to an unprecedented disturbance
Nunes, I. M., Jurburg, S., Jacquiod, S. J. A., Brejnrod, A. D., Falcão Salles, J., Priemé, Anders & Sørensen, Søren Johannes, Feb 2018, In: Biology and Fertility of Soils. 54, 2, p. 189–202 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fasting decreases plasma FGF21 in obese subjects and the expression of FGF21 receptors in adipose tissue in both lean and obese subjects
Nygaard, E. B., Ørskov, Cathrine, Almdal, Thomas Peter, drb459, drb459 & Andersen, B., 2018, In: Journal of Endocrinology. 239, 1, p. 73-80Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Application of urinary proteomics as possible risk predictor of renal and cardiovascular complications in patients with type 2-diabetes and microalbuminuria
Oellgaard, J., Gæde, P., Persson, F., Rossing, Peter, Parving, H. & Pedersen, Oluf Borbye, 2018, In: Journal of Diabetes and its Complications. 32, 12, p. 1133-1140Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reduced risk of heart failure with intensified multifactorial intervention in individuals with type 2 diabetes and microalbuminuria: 21 years of follow-up in the randomised Steno-2 study
Oellgaard, J., Gaede, P., Rossing, Peter, Rorth, R., Køber, Lars Valeur, Parving, H. & Pedersen, Oluf Borbye, 2018, In: Diabetologia. 61, 8, p. 1724-1733Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Intestinotrophic Effects of Glucagon-Like Peptide-2 in Relation to Intestinal Neoplasia
Orhan, Adile, Gögenur, Ismail & Kissow, Hannelouise, 2018, In: The Journal of clinical endocrinology and metabolism. 103, 8, p. 2827-2837Research output: Contribution to journal › Review › Research › peer-review
- Published
Recovery of gut microbiota of healthy adults following antibiotic exposure
Palleja, A., Mikkelsen, K. H., Forslund, S. K., Kashani, A., Allin, K. H., Nielsen, T., Hansen, T. H., Liang, S., Feng, Q., Zhang, C., Pyl, P. T., Coelho, L. P., Yang, H., Wang, J., Typas, A., Nielsen, M. F., Nielsen, H. B., Bork, P., Wang, J., Vilsbøll, T. & 4 others, , Nov 2018, In: Nature Microbiology. 3, 11, p. 1255-1265 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exposure to the gut microbiota drives distinct methylome and transcriptome changes in intestinal epithelial cells during postnatal development
Pan, W., Sommer, F., Falk-Paulsen, M., Ulas, T., Best, P., Fazio, A., Kachroo, P., Luzius, A., Jentzsch, M., Rehman, A., Mueller, F., Lengauer, T., Walter, J., Kuenzel, S., Baines, J. F., Schreiber, S., Franke, A., Schultze, J. L., Backhed, F. & Rosenstiel, P., 2018, In: Genome Medicine. 10, p. 1-15 27.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Outcome of childhood obesity
Pedersen, D. C., Sørensen, Thorkild I.A. & Baker, J. L., 2018, Eating Disorders and Obesity in Children and Adolescents. Hebebrand, J. & Herpertz-Dahlmann, B. (eds.). 1 ed. St. Louis, Missouri: Elsevier, p. 165-169 5 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
A computational framework to integrate high-throughput "-omics" datasets for the identification of potential mechanistic links
Pedersen, H. K., Forslund, S. K., Gudmundsdottir, V., Petersen, A. Ø., Hildebrand, F., Hyötyläinen, T., Nielsen, T., Hansen, Torben, Bork, P., Ehrlich, S. D., Brunak, Søren, Oresic, M., Pedersen, Oluf Borbye & Nielsen, H. B., 2018, In: Nature Protocols. 13, 12, p. 2781-2800 20 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of protein phosphatase involvement in the AT2 receptor-induced activation of endothelial nitric oxide synthase
Peluso, A., 2018, In: Clinical Science.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hemodynamic Effects of Glucagon: A Literature Review
Petersen, K. M., Bogevig, S., Holst, Jens Juul, Knop, Filip Krag & Christensen, Mikkel Bring, 2018, In: Journal of Clinical Endocrinology & Metabolism. 103, 5, p. 1804-1812Research output: Contribution to journal › Review › Research › peer-review
- Published
Response to Letter to the Editor: "Hemodynamic Effects of Glucagon: A Literature Review"
Petersen, K. M., Bøgevig, S., Holst, Jens Juul, Knop, Filip Krag & Christensen, Mikkel Bring, 2018, In: The Journal of clinical endocrinology and metabolism. 103, 12, p. 4480-4481 2 p.Research output: Contribution to journal › Comment/debate › Research
- Published
Delayed age at transfer of adoptees to adoptive parents is associated with increased mortality irrespective of social class of the adoptive parents: a cohort study
Petersen, L., Andersen, Per Kragh, Sørensen, Thorkild I.A. & Mortensen, Erik Lykke, 2018, In: BMC Public Health. 18, 1, 7 p., 435.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhibiting RHOA Signaling in Mice Increases Glucose Tolerance and Numbers of Enteroendocrine and Other Secretory Cells in the Intestine
Petersen, N., Frimurer, Thomas Michael, Pedersen, M. T., Egerod, Kristoffer Lihme, Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Grapin-Botton, A., Jensen, Kim Bak & Schwartz, Thue W., 2018, In: Gastroenterology. 155, 4, p. 1164-1176 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Obesity is associated with vitamin D deficiency in Danish children and adolescents
Plesner, J. L., Dahl, M., Fonvig, Cilius Esmann, Nielsen, T. R. H., Kloppenborg, J. T., Pedersen, Oluf Borbye, Hansen, Torben & Holm, Jens-Christian, 26 Jan 2018, In: Journal of Pediatric Endocrinology and Metabolism. 31, 1, p. 53-61 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Maternal obesity reprograms offspring's executive brain centers in a sex-specific manner? An Editorial for "Perinatal high fat diet and early life methyl donor supplementation alter one carbon metabolism and DNA methylation in the brain" on page 362
Plucinska, Kaja & Barger, S. W., 2018, In: Journal of Neurochemistry. 145, 5, p. 358-361Research output: Contribution to journal › Editorial › Research
- Published
Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6
Prins, B. P., Mead, T. J., Brody, J. A., Sveinbjornsson, G., Ntalla, I., Bihlmeyer, N. A., van den Berg, M., Bork-Jensen, J., Cappellani, S., Van Duijvenboden, S., Klena, N. T., Gabriel, G. C., Liu, X., Gulec, C., Grarup, N., Haessler, J., Hall, L. M., Iorio, A., Isaacs, A., Li-Gao, R. & 31 others, , 17 Jul 2018, In: Genome Biology. 19, 17 p., 87.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Distinct signalling properties of insulin receptor substrate (IRS)-1 and IRS-2 in mediating insulin/IGF-1 action
Rabiee, A., Krüger, M., Ardenkjær-Larsen, J., Ronald Kahn, C. & Emanuelli, Brice, 2018, In: Cellular Signalling. 47, p. 1-15Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of Preceding Ethanol Intake on Glucose Response to Low-Dose Glucagon in Individuals With Type 1 Diabetes: A Randomized, Placebo-Controlled, Crossover Study
Ranjan, A., Nørgaard, Kirsten, Tetzschner, R., Steineck, I. I. K., Clausen, T. R., Holst, Jens Juul, Madsbad, Sten & Schmidt, S., 2018, In: Diabetes Care. 41, 4, p. 797-806Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Relationship between Optimum Mini‐doses of Glucagon and Insulin Levels when Treating Mild Hypoglycaemia in Patients with Type 1 Diabetes: A Simulation Study
Ranjan, A., Wendt, S. L., Schmidt, S., Madsbad, Sten, Holst, Jens Juul, Madsen, H., Knudsen, C. B., Jørgensen, J. B. & Nørgaard, Kirsten, 2018, In: Basic & Clinical Pharmacology & Toxicology. 122, 3, p. 322-330Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Antibiotic exposure in early life and childhood overweight and obesity: A systematic review and meta-analysis
Rasmussen, S. H., Shrestha, S., Bjerregaard, L. G., Ängquist, Lars, Baker, J. L., Jess, T. & Allin, K. H., 2018, In: Diabetes, Obesity and Metabolism. 20, 6, p. 1508–1514Research output: Contribution to journal › Review › Research › peer-review
- Published
Cholecystokinin secretion is suppressed by glucagon-like peptide-1: clue to the mechanism of the adverse gallbladder events of GLP-1-derived drugs
Rehfeld, Jens Frederik, Knop, Filip Krag, Asmar, A., Madsbad, Sten, Holst, Jens Juul & Asmar, M., 2018, In: Scandinavian Journal of Gastroenterology. 53, 12, p. 1429-1432Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Whole-genome and Transcriptome Sequencing of Prostate Cancer Identify New Genetic Alterations Driving Disease Progression
Ren, S., Wei, G-H., Liu, D., Wang, L., Hou, Y., Zhu, S., Peng, L., Zhang, Q., Cheng, Y., Su, H., Zhou, X., Zhang, J., Li, F., Zheng, H., Zhao, Z., Yin, C., He, Z., Gao, X., Zhau, H. E., Chu, C-Y. & 42 others, , 2018, In: European Urology. 73, 3, p. 322-339 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structure-Activity Investigations and Optimisations of Non-metabolite Agonists for the Succinate Receptor 1
Ulven, Elisabeth Rexen, Trauelsen, Mette, Brvar, M., Lückmann, Michael, Bielefeldt, L. Ø., Jensen, L. K. I., Schwartz, Thue W. & Frimurer, Thomas Michael, 2018, In: Scientific Reports. 8, 1, p. 1-18 10010.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Perturbations in the p53/miR-34a/SIRT1 pathway in the R6/2 Huntington's disease model
Reynolds, R. H., Petersen, M. H., Willert, C. W., Heinrich, M., Nymann, N., Dall, M., Treebak, Jonas Thue, Björkqvist, M., Silahtaroglu, Asli, Hasholt, Lis Frydenreich & Nørremølle, Anne, 2018, In: Molecular and Cellular Neuroscience. 88, p. 118-129Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Diagnostik og behandling af maturity onset diabetes of the young type 3
Rose, K., Christensen, A. S., Storgaard, H., Hædersdal, S., Hansen, Torben, Knop, Filip Krag & Vilsbøll, Tina, 2018, In: Ugeskrift for Laeger. 180, 6 p., V06170502.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes
Bipolar Disorder and Schizophrenia Working Group of the Psychiatric Genomics Consortium douglas.ruderfer@vanderbilt.edu, B. D. A. S. W. G. O. T. P. G. C. D. R. E., Psychosis Endophenotypes International Consortium, P. E. I. C. & Wellcome Trust Case-Control Consortium, W. T. C. C., 14 Jun 2018, In: Cell. 173, 7, p. 1705-1715.e16Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of metformin on plasma metabolite profile in the Copenhagen Insulin and Metformin Therapy (CIMT) trial
Safai, N., Suvitaival, T., Ali, A., Spegel, P., Al-Majdoub, M., Carstensen, B., drb459, drb459 & Ridderstråle, M., 2018, In: Diabetic Medicine. 35, 7, p. 944-953Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of a multifactorial treatment programme on clinical outcomes and cardiovascular risk estimates: a retrospective cohort study from a specialised diabetes centre in Denmark
Safai, N., Carstensen, Bendix, drb459, drb459 & Ridderstråle, M., 1 Mar 2018, In: BMJ Open. 8, 3, e019214.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Variation in mitochondrial respiratory capacity and myosin heavy chain composition in repeated muscle biopsies
Sahl, Ronni Eg, Morville, T., Kraunsøe, R., Dela, Flemming, Helge, Jørn Wulff & Larsen, Steen, 1 Sep 2018, In: Analytical Biochemistry. 556, p. 119-124 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A carbohydrate-reduced high-protein diet acutely decreases postprandial and diurnal glucose excursions in type 2 diabetes patients
Samkani, A., fbg982, fbg982, Kandel, D., Kjaer, S., Astrup, A., Deacon, Carolyn F., Holst, Jens Juul, Madsbad, Sten, Rehfeld, Jens Frederik, Haugaard, Steen Bendix & Krarup, T., 2018, In: British Journal of Nutrition. 119, 8, p. 910-917 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The acute effects of dietary carbohydrate reduction on postprandial responses of non-esterified fatty acids and triglycerides: a randomized trial
Samkani, A., fbg982, fbg982, Anholm, C., Astrup, A., Deacon, Carolyn F., Holst, Jens Juul, Madsbad, S., Boston, R., Krarup, T. & Haugaard, Steen Bendix, 2018, In: Lipids in Health and Disease. 17, 9 p., 295.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Acute effects of dietary carbohydrate restriction on glycemia, lipemia and appetite regulating hormones in normal-weight to obese subjects
Samkani, A. A., fbg982, fbg982, Thomsen, M. N., Astrup, A., Deacon, Carolyn F., Holst, Jens Juul, Madsbad, Sten, Rehfeld, Jens Frederik, Krarup, T. & Haugaard, Steen Bendix, 2018, In: Nutrients. 10, 9, 14 p., 1285.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Brown Fat AKT2 Is a Cold-Induced Kinase that Stimulates ChREBP-Mediated De Novo Lipogenesis to Optimize Fuel Storage and Thermogenesis
Sanchez-Gurmaches, J., Tang, Y., Jespersen, N. Z., Wallace, M., Martinez Calejman, C., Gujja, S., Li, H., Edwards, Y. J. K., Wolfrum, C., Metallo, C. M., Nielsen, S., Schéele, Camilla Charlotte Nielsen & Guertin, D. A., 9 Jan 2018, In: Cell Metabolism. 27, 1, p. 195-209.e6Research output: Contribution to journal › Journal article › Research › peer-review
- Published
About this book
Sandøe, Peter, Jensen, Karsten Klint & Whiteley, Louise, Jan 2018, RCR – A Danish textbook for courses in Responsible Conduct of Research. Jensen, K. K., Whiteley, L. & Sandøe, P. (eds.). 3 ed. Frederiksberg: Department of Food and Resource Economics, University of Copenhagen, p. 8-11 4 p.Research output: Chapter in Book/Report/Conference proceeding › Preface/postscript › Education
- Published
Gestational weight gain charts for different body mass index groups for women in Europe, North America, and Oceania
Santos, S., Eekhout, I., Voerman, E., Gaillard, R., Barros, H., Charles, M-A., Chatzi, L., Chevrier, C., Chrousos, G. P., Corpeleijn, E., Costet, N., Crozier, S., Doyon, M., Eggesbo, M., Fantini, M. P., Farchi, S., Forastiere, F., Gagliardi, L., Georgiu, V., Godfrey, K. M. & 60 others, , 5 Nov 2018, In: BMC Medicine. 16, 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Betydning af sædcellens epigenetik for befrugtning og fosterudvikling
Saupstad, M., Andersen, E. & Barrès, Romain, 2018, In: Ugeskrift for Laeger. 180, p. 2-5 V02180152.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of a diet rich in arabinoxylan and resistant starch compared with a diet rich in refined carbohydrates on postprandial metabolism and features of the metabolic syndrome
Schioldan, A. G., Gregersen, S., Hald, S., Bjørnshave, A., Bohl, M., Hartmann, Bolette, Holst, Jens Juul, Stødkilde-Jørgensen, H. & Hermansen, K., Mar 2018, In: European Journal of Nutrition. 57, 2, p. 795–807Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of casein, hydrolyzed casein, and whey proteins on urinary and postprandial plasma metabolites in overweight and moderately obese human subjects
Schmedes, M. S., Bendtsen, L. Q., Gomes, S., Liaset, B., Holst, Jens Juul, Ritz, C., Reitelseder, S., Sjödin, Anders Mikael, Astrup, A., Young, J. F., Sundekilde, U. K. & Bertram, H. C., 2018, In: Journal of the Science of Food and Agriculture. 98, 15, p. 5598-5605 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic predisposition to adiposity is associated with increased objectively assessed sedentary time in young children
Schnurr, T. M., Viitasalo, A., Eloranta, A., Damsgaard, Camilla Trab, Mahendran, Y., Have, C. T., Väistö, J., Hjorth, Mads Fiil, Christensen, L. B., Brage, S., Atalay, M., Lyytikäinen, L., Lindi, V., Lakka, T., Michaelsen, Kim F., Kilpeläinen, Tuomas O. & Hansen, Torben, 2018, In: International Journal of Obesity. 42, 1, p. 111-114 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bifidobacteria or fiber protects against diet-induced microbiota-mediated colonic mucus deterioration
Schroeder, B. O., Birchenough, G. M. H., Ståhlman, M., Arike, L., Johansson, M. E. V., Hansson, G. C. & Bäckhed, F., 2018, In: Cell Host & Microbe. 23, 1, p. 27-40 + e1-e7 22 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Proteomics Analysis of Skeletal Muscle from Leptin-Deficient ob/ob Mice Reveals Adaptive Remodeling of Metabolic Characteristics and Fiber Type Composition
Schönke, M., Björnholm, M., Chibalin, A. V., Zierath, Juleen R & Deshmukh, Atul Shahaji, 2018, In: Proteomics. 18, 5-6, p. 1-11 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Metabolomic profiling of maternal hair suggests rapid development of intrahepatic cholestasis of pregnancy
Seymour, J. V. D., Tu, S., He, X., Zhang, H., Han, T., Baker, P. N. & Sulek, K., 2018, In: Metabolomics. 14, 6, p. 1-5 79.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Skeletal muscle O-GlcNAc transferase is important for muscle energy homeostasis and whole-body insulin sensitivity
Shi, H., Munk, A., Nielsen, T. S., Daughtry, M. R., Larsson, L., Li, S., Høyer, K. F., Geisler, H. W., Sulek, K., Kjøbsted, R., Fisher, T., Andersen, M. M., Shen, Z., Hansen, U. K., England, E. M., Cheng, Z., Højlund, K., Wojtaszewski, J., Yang, X., Hulver, M. W. & 3 others, , 2018, In: Molecular Metabolism. 11, p. 160-177 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Accurate genotyping across variant classes and lengths using variant graphs
Sibbesen, Jonas Andreas, Maretty, L., Krogh, Anders, Petersen, Bent, Sibbesen, Jonas Andreas, Liu, S., Have, C. T., Bork-Jensen, J., Guo, X., Hansen, Torben, Krogh, Anders, Sørensen, Thorkild I.A., Pedersen, Oluf Borbye, Wang, J. & Brunak, Søren, 2018, In: Nature Genetics. 50, p. 1054-1059 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The glucagon like peptide-2 'axis': Capacity for production and response following intestinal resection or repair of gastroschisis in infants
Sigalet, D. L., Lam, V., Brindle, M., Boctor, D., Wallace, L., de Heuval, E., Hartmann, Bolette & Holst, Jens Juul, 2018, In: Journal of Pediatric Surgery. 53, 5, p. 898-904Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Estimating the causal effect of body mass index on hay fever, asthma and lung function using Mendelian randomization
Skaaby, T., Taylor, A. E., Thuesen, B. H., Jacobsen, R. K., Friedrich, N., Møllehave, L. T., Hansen, S., Larsen, S. C., Völker, U., Nauck, M., Völzke, H., Hansen, Torben, Pedersen, Oluf Borbye, Jørgensen, T., Paternoster, L., Munafò, M., Grarup, N. & Linneberg, Allan René, 2018, In: Allergy. 73, 1, p. 153-164 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Associations of genetic determinants of serum vitamin B12 and folate concentrations with hay fever and asthma: a Mendelian randomization meta-analysis
Skaaby, T., Taylor, A. E., Jacobsen, R. K., Møllehave, L. T., Friedrich, N., Thuesen, B. H., Shabanzadeh, D. M., Paternoster, L., Völker, U., Nauck, M., Völzke, H., Munafò, M., Hansen, Torben, Pedersen, Oluf Borbye, Jørgensen, T., Grarup, N. & Linneberg, Allan René, 2018, In: European Journal of Clinical Nutrition. 72, 2, p. 264–271 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic risk score of insulin resistance risk variants is associated with increased risk of coronary artery disease in patients referred to coronary angiography
Skals, R. K., Krogager, M. L., Appel, E. V. R., Schnurr, T. M., Have, C. T., Gislason, Gunnar Hilmar, Poulsen, Henrik Enghusen, Køber, Lars Valeur, Engstrøm, Thomas, Stender, S., Hansen, Torben, Grarup, N., Andersson, C., Torp-Pedersen, C. & Weeke, P. E., 2018, In: European Heart Journal. 39, p. 752-753Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Separate effects of glucagon like peptide-2 (GLP-2) and glucose-dependent insulinotropic polypeptide (GIP) on bone remodelling
Skov-Jeppesen, Kirsa, Svane, M., Martinussen, C., Gabe, M., Gasbjerg, Lærke Smidt, Madsbad, Sten, Holst, Jens Juul, Rosenkilde, Mette & Hartmann, Bolette, 2018, In: Diabetologia. 61, S1, p. S245-S245 501.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Genome-Wide Interactions with Dairy Intake for Body Mass Index in Adults of European Descent
Smith, C. E., Follis, J. L., Dashti, H. S., Tanaka, T., Graff, M., Fretts, A. M., Kilpeläinen, T. O., Wojczynski, M. K., Richardson, K., Nalls, M. A., Schulz, C-A., Liu, Y., Frazier-Wood, A. C., van Eekelen, E., Wang, C., de Vries, P. S., Mikkilä, V., Rohde, R., Psaty, B. M., Hansen, T. & 43 others, , 2018, In: Molecular Nutrition & Food Research. 62, 3, p. 1-12 12 p., 1700347.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Renoprotective effects of dulaglutide in patients with T2DM and CKD
Sorensen, Charlotte Mehlin & Holst, Jens Juul, 2018, In: Nature Reviews. Nephrology. 14, 11, p. 659-660Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Glucose Tolerance Tests and Osteocalcin Responses in Healthy People
Starup-Linde, J., Westberg-Rasmussen, S., Lykkeboe, S., Handberg, A., Hartmann, Bolette, Holst, Jens Juul, Hermansen, K., Vestergaard, P. & Gregersen, S., 2018, In: Frontiers in Endocrinology. 9Research output: Contribution to journal › Journal article › Research › peer-review
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Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
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Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets
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The isoenzyme pattern of LDH does not play a physiological role; except perhaps during fast transitions in energy metabolism
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