Novo Nordisk Foundation Center for Basic Metabolic Research

  1. 2018
  2. Published

    Papio spp. Colon microbiome and its link to obesity in pregnancy

    Li, Xuan Ji, Rensing, C., Taylor, W. L., Costelle, C., Brejnrod, A. D., Ferry, R. J. ,. J., Higgins, P. B., Folli, F., Kottapalli, K. R., Hubbard, G. B., Dick, E. J. ,. J., Yooseph, S., Nelson, K. E. & Schlabritz-Loutsevitch, N., Dec 2018, In: Journal of Medical Primatology. 47, 6, p. 393-401

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders

    Ligthart, S., Vaez, A., Vosa, U., Stathopoulou, M. G., de Vries, P. S., Prins, B. P., Van der Most, P. J., Tanaka, T., Naderi, E., Rose, L. M., Wu, Y., Karlsson, R., Barbalic, M., Lin, H., Pool, R., Zhu, G., Mace, A., Sidore, C., Trompet, S., Mangino, M. & 266 others, Sabater-Lleal, M., Kemp, J. P., Abbasi, A., Kacprowski, T., Verweij, N., Smith, A. V., Huang, T., Marzi, C., Feitosa, M. F., Lohman, K. K., Kleber, M. E., Milaneschi, Y., Mueller, C., Huq, M., Vlachopoulou, E., Lyytikainen, L., Oldmeadow, C., Deelen, J., Perola, M., Zhao, J., Feenstra, B., Amini, M., Lahti, J., Schraut, K. E., Fornage, M., Suktitipat, B., Chen, W., Li, X., Nutile, T., Malerba, G., Luan, J., Bak, T., Schork, N., Del Greco, F. M., Thiering, E., Mahajan, A., Marioni, R. E., Mihailov, E., Eriksson, J., Ozel, A. B., Zhang, W., Nethander, M., Cheng, Y., Aslibekyan, S., Ang, W., Gandin, I., Yengo, L., Portas, L., Kooperberg, C., Hofer, E., Rajan, K. B., Schurmann, C., den Hollander, W., Ahluwalia, Tarun Veer Singh, Zhao, J., Draisma, H. H. M., Ford, I., Timpson, N., Teumer, A., Huang, H., Wahl, S., Liu, Y., Huang, J., Uh, H., Geller, F., Joshi, P. K., Yanek, L. R., Trabetti, E., Lehne, B., Vozzi, D., Verbanck, M., Biino, G., Saba, Y., Meulenbelt, I., O'Connell, J. R., Laakso, M., Giulianini, F., Magnusson, P. K. E., Ballantyne, C. M., Hottenga, J. J., Montgomery, G., Rivadineira, F., Rueedi, R., Steri, M., Herzig, K., Stott, D. J., Menni, C., Franberg, M., St Pourcain, B., Felix, S. B., Pers, Tune H, Bakker, S. J. L., Kraft, P., Peters, A., Vaidya, D., Delgado, G., Smit, J. H., Grossmann, V., Sinisalo, J., Seppala, I., Williams, S. R., Holliday, E. G., Moed, M., Langenberg, C., Raikkonen, K., Ding, J., Campbell, H., Sale, M. M., Chen, Y. I., James, A. L., Ruggiero, D., Soranzo, N., Hartman, C. A., Smith, E. N., Berenson, G. S., Fuchsberger, C., Hernandez, D., Tiesler, C. M. T., Giedraitis, V., Liewald, D., Fischer, K., Mellstrom, D., Larsson, A., Wang, Y., Scott, W. R., Lorentzon, M., Beilby, J., Ryan, K. A., Pennell, C. E., Vuckovic, D., Balkau, B., Concas, M. P., Schmidt, R., de Leon, C. F. M., Bottinger, E. P., Kloppenburg, M., Paternoster, L., Boehnke, M., Musk, A. W., Willemsen, G., Evans, D. M., Madden, P. A. F., Kahonen, M., Kutalik, Z., Zoledziewska, M., Karhunen, V., Kritchevsky, S. B., Sattar, N., Lachance, G., Clarke, R., Harris, T. B., Raitakari, O. T., Attia, J. R., Van Heemst, D., Kajantie, E., Sorice, R., Gambaro, G., Scott, R. A., Hicks, A. A., Ferrucci, L., Standl, M., Lindgren, C. M., Starr, J. M., Karlsson, M., Lind, L., Li, J. Z., Chambers, J. C., Mori, T. A., de Geus, E. J. C. N., Heath, A. C., Martin, N. G., Auvinen, J., Buckley, B. M., de Craen, A. J. M., Waldenberger, M., Strauch, K., Meitinger, T., Scott, R. J., McEvoy, M., Beekman, M., Bombieri, C., Ridker, P. M., Mohlke, K. L., Pedersen, N. L., Morrison, A. C., Boomsma, D. I., Whitfield, J. B., Strachan, D. P., Hofman, A., Vollenweider, P., Cucca, F., Jarvelin, M., Jukema, J. W., Spector, T. D., Hamsten, A., Zeller, T., Uitterlinden, A. G., Nauck, M., Gudnason, V., Qi, L., Grallert, H., Borecki, I. B., Rotter, J. I., Maerz, W., Wild, P. S., Lokki, M., Boyle, M., Salomaa, V., Melbye, M., Eriksson, J. G., Wilson, J. F., Penninx, B. W. J. H., Becker, D. M., Worrall, B. B., Gibson, G., Krauss, R. M., Ciullo, M., Zaza, G., Wareham, N. J., Oldehinkel, A. J., Palmer, L. J., Murray, S. S., Pramstaller, P. P., Bandinelli, S., Heinrich, J., Ingelsson, E., Deary, I. J., Magi, R., Vandenput, L., van der Harst, P., Desch, K. C., Kooner, J. S., Ohlsson, C., Hayward, C., Lehtimaki, T., Shuldiner, A. R., Arnett, D. K., Beilin, L. J., Robino, A., Froguel, P., Pirastu, M., Jess, T., Koenig, W., Loos, Ruth, Evans, D. A., Schmidt, H., Smith, G. D., Slagboom, P. E., Eiriksdottir, G., Morris, A. P., Psaty, B. M., Tracy, R. P., Nolte, I. M., Boerwinkle, E., Visvikis-Siest, S., Reiner, A. P., Gross, M., Bis, J. C., Franke, L., Franco, O. H., Benjamin, E. J., Chasman, D. I., Dupuis, J., Snieder, H., Dehghan, A. & Alizadeh, B. Z., 1 Nov 2018, In: American Journal of Human Genetics. 103, 5, p. 691-706

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Common and Rare Coding Genetic Variation Underlying the Electrocardiographic PR Interval

    Lin, H., van Setten, J., Smith, A. V., Bihlmeyer, N. A., Warren, H. R., Brody, J. A., Radmanesh, F., Hall, L., Grarup, N., Müller-Nurasyid, M., Boutin, T., Verweij, N., Lin, H. J., Li-Gao, R., van den Berg, M. E., Marten, J., Weiss, S., Prins, B. P., Haessler, J., Lyytikäinen, L-P. & 81 others, Mei, H., Harris, T. B., Launer, L. J., Li, M., Alonso, A., Soliman, E. Z., Connell, J. M., Huang, P. L., Weng, L., Jameson, H. S., Hucker, W., Hanley, A., Tucker, N. R., Chen, Y. I., Bis, J. C., Rice, K. M., Sitlani, C. M., Kors, J. A., Xie, Z., Wen, C., Magnani, J. W., Nelson, C. P., Kanters, Jørgen K., Sinner, M. F., Strauch, K., Peters, A., Waldenberger, M., Meitinger, T., Bork-Jensen, J., Pedersen, Oluf Borbye, Linneberg, Allan René, Rudan, I., de Boer, R. A., van der Meer, P., Yao, J., Guo, X., Taylor, K. D., Sotoodehnia, N., Rotter, J. I., Mook-Kanamori, D. O., Trompet, S., Rivadeneira, F., Uitterlinden, A., Eijgelsheim, M., Padmanabhan, S., Smith, B. H., Völzke, H., Felix, S. B., Homuth, G., Völker, U., Mangino, M., Spector, T. D., Bots, M. L., Perez, M., Kähönen, M., Raitakari, O. T., Gudnason, V., Arking, D. E., Munroe, P. B., Psaty, B. M., van Duijn, C. M., Benjamin, E. J., Rosand, J., Samani, N. J., Hansen, Torben, Kääb, S., Polasek, O., van der Harst, P., Heckbert, S. R., Jukema, J. W., Stricker, B. H., Hayward, C., Dörr, M., Jamshidi, Y., Asselbergs, F. W., Kooperberg, C., Lehtimäki, T., Wilson, J. G., Ellinor, P. T., Lubitz, S. A. & Isaacs, A., 2018, In: Circulation. Genomic and precision medicine. 11, 5, p. 1-11 e002037.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Elucidation of the intrinsic optical properties of hydrogen-bonded and protonated flavin chromophores by photodissociation action spectroscopy

    Lincke, K., Langeland, J., Madsen, A. Ø., Kiefer, H. V., Skov, L., Gruber, E., Mikkelsen, Kurt Valentin, Andersen, L. H. & Nielsen, Mogens Brøndsted, 2018, In: Physical Chemistry Chemical Physics. 20, 45, p. 28678-28684 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    One-carbon metabolism markers are associated with cardiometabolic risk factors

    Lind, M. V., Lauritzen, Lotte, drb459, drb459, Hansen, Torben, Pedersen, Oluf Borbye, Kristensen, M. B. & Ross, A. B., 2018, In: Nutrition, Metabolism & Cardiovascular Diseases. 28, 4, p. 402-410 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Predicting albuminuria response to spironolactone treatment with urinary proteomics in patients with type 2 diabetes and hypertension

    Lindhardt, M., Persson, F., Oxlund, C., Jacobsen, I. A., Zürbig, P., Mischak, H., Rossing, Peter & Heerspink, H. J. L., Feb 2018, In: Nephrology, Dialysis, Transplantation. 33, 2, p. 296-303 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Uncovering the anatomical and molecular landscape of the developing entorhinal cortex.

    Liu, Y., Bergmann, T. B., Peralvo Vidal, Juan Miguel, Lee, J., Mori, Yuki, Seemann, Ernst Stefan, Pihl, M., Thomsen, Preben Dybdahl, Gorodkin, Jan, Hyttel, P., Pers, Tune H, witter, M. & Hall, Vanessa Jane, 2018.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  9. Published

    Genes that make you fat, but keep you healthy

    Loos, Ruth & Kilpeläinen, Tuomas O., 2018, In: Journal of Internal Medicine. 284, 5, p. 450-463 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Inhibitor-Induced Conformational Changes in ASIC1A

    Lund, Camilla, Borg, C. B., Lynagh, T. & Pless, Stephan, 2 Feb 2018, p. 130A-130A.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  11. Published

    Brown fat: the biological furnace that could burn away obesity

    Lund, Jens, Peics, J. & Gerhart-Hines, Zach, 2018, In: Biozoom. 20, 3, p. 4-6 3 p.

    Research output: Contribution to journalJournal articleResearch

  12. Published

    Enterochromaffin 5-HT cells - A major target for GLP-1 and gut microbial metabolites

    Lund, M. L., Egerod, Kristoffer Lihme, Engelstoft, M. S., Dmytriyeva, O., Theodorsson, E., Patel, B. A. & Schwartz, Thue W., 2018, In: Molecular Metabolism. 11, p. 70-83 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Cold-Activated Lipid Dynamics in Adipose Tissue Highlights a Role for Cardiolipin in Thermogenic Metabolism

    Lynes, M. D., Shamsi, F., Sustarsic, E. G., Leiria, L. O., Wang, C. H., Su, S. C., Huang, T. L., Gao, Fei, Narain, N. R., Chen, E. Y., Cypess, A. M., Schulz, T. J., Gerhart-Hines, Zach, Kiebish, M. A. & Tseng, Y. H., 2018, In: Cell Reports. 24, 3, p. 781-790 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Individual and combined glucose-lowering effects of glucagon receptor antagonism and dipeptidyl peptidase-4 inhibition

    Maagensen, H., Haedersdal, S., Lund, A., Nielsen-Hannerup, E., Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 2018, In: Diabetologia. 61, p. S246-S247

    Research output: Contribution to journalConference abstract in journalResearch

  15. Published

    Treatment with GLP-1 Receptor Agonists

    Madsbad, Sten & Holst, Jens Juul, 2018, Diabetes: Epidemiology, Genetics, Pathogenesis, Diagnosis, Prevention, and Treatment. Bonora, E. & DeFronzo, R. (eds.). Springer, 45 p. (Endocrinology).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  16. Published

    The role of the bacterial microbiota in alcoholic and non-alcoholic fatty liver disease

    Madsen, Anne Lundager, Brach, Thorsten, Kern, T., Bak, Emilie Glad, Nielsen, T. & Arumugam, Mani, 9 Nov 2018, The Human Gut-Liver-Axis in Health and Disease. Springer, p. 89-104 16 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterEducation

  17. Published

    Antifibrotic and molecular aspects of rifaximin in alcoholic liver disease: study protocol for a randomized controlled trial

    Madsen, B. S., Trebicka, J., Thiele, M., Israelsen, M., Arumugam, Mani, Havelund, T. & Krag, A., 2018, In: Trials. 19, p. 1-5 5 p., 143.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Evolutionary conservation of the allosteric activation of factor VIIa by tissue factor in lamprey: comment

    Madsen, J. J., Persson, E. & Olsen, O. H., 2018, In: Journal of Thrombosis and Haemostasis. 16, 7, p. 1450-1454

    Research output: Contribution to journalComment/debateResearchpeer-review

  19. Published

    Genome-wide association analyses identify 39 new susceptibility loci for diverticular disease

    Maguire, L. H., Handelman, S. K., Du, X., Chen, Y., Pers, Tune H & Speliotes, E. K., 2018, In: Nature Genetics. 50, 10, p. 1359-1365

    Research output: Contribution to journalLetterResearchpeer-review

  20. Published

    Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps

    Mahajan, A., Taliun, D., Thurner, M., Robertson, N. R., Torres, J. M., Rayner, N. W., Payne, A. J., Steinthorsdottir, V., Scott, R. A., Grarup, N., Cook, J. P., Schmidt, E. M., Wuttke, M., Sarnowski, C., Magill, R., Nano, J., Gieger, C., Trompet, S., Lecoeur, C., Preuss, M. H. & 95 others, Prins, B. P., Guo, X., Bielak, L. F., Below, J. E., Bowden, D. W., Chambers, J. C., Kim, Y. J., Ng, M. C. Y., Petty, L. E., Sim, X., Zhang, W., Bennett, A. J., Bork-Jensen, J., Brummett, C. M., Canouil, M., Kardt, K. E., Fischer, K., Kardia, S. L. R., Kronenberg, F., Lall, K., Liu, C., Locke, A. E., Luan, J., Ntalla, L., Nylander, V., Schoenherr, S., Schurmann, C., Yengo, L., Bottinger, E. P., Brandslund, I., Christensen, C., Dedoussis, G., Florez, J. C., Ford, I., France, O. H., Frayling, T. M., Giedraitis, V., Hackinger, S., Hattersley, A. T., Herder, C., Ikram, M. A., Ingelsson, M., Jorgensen, M. E., Jorgensen, T., Kriebel, J., Kuusisto, J., Ligthart, S., Lindgren, C. M., Linneberg, Allan René, Lyssenko, V., Mamakou, V., Meitinger, T., Mohlke, K. L., Morris, A. D., Nadkarni, G., Pankow, J. S., Peters, A., Sattar, N., Stancakova, A., Strauch, K., Taylor, K. D., Thorand, B., Thorleifsson, G., Thorsteinsdottir, U., Tuomilehto, J., Witte, D. R., Dupuis, J., Peyser, P. A., Zeggini, E., Loos, Ruth, Froguel, P., Ingelsson, E., Lind, L., Groop, L., Laakso, M., Collins, F. S., Jukema, J. W., Palmer, C. N. A., Grallert, H., Metspalu, A., Dehghan, A., Koettgen, A., Abecasis, G. R., Meigs, J. B., Rotter, J. I., Marchini, J., Pedersen, Oluf Borbye, Hansen, Torben, Langenberg, C., Wareham, N. J., Stefansson, K., Gloyn, A. L., Morris, A. P., Boehnke, M. & McCarthy, M. I., 2018, In: Nature Genetics. 50, 11, p. 1505-1513

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes

    Mahajan, A., Wessel, J., Willems, S. M., Zhao, W., Robertson, N. R., Chu, A. Y., Gan, W., Kitajima, H., Taliun, D., Rayner, N. W., Guo, X., Lu, Y., Li, M., Jensen, R. A., Hu, Y., Huo, S., Lohman, K. K., Zhang, W., Cook, J. P., Prins, B. P. & 32 others, Flannick, J., Grarup, N., Trubetskoy, V. V., Kravic, J., Kim, Y. J., Rybin, D. V., Yaghootkar, H., Müller-Nurasyid, M., Meidtner, K., Li-Gao, R., Varga, T. V., Marten, J., Li, J., Afzal, Shoaib, Bork-Jensen, J., Tybjærg-Hansen, Anne, Jørgensen, M. E., Jørgensen, T., Kovacs, P., Linneberg, Allan René, Liu, J., Nielsen, S. F., Rode, L., Witte, D. R., Hansen, Torben, Karpe, F., Lind, L., Loos, R. J. F., Nordestgaard, Børge, Pedersen, Oluf Borbye, ExomeBP Consortium, E. C. & V Varga, Tibor, Apr 2018, In: Nature Genetics. 50, 4, p. 559-571 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    The Impact of Dietary Fiber on Gut Microbiota in Host Health and Disease

    Makki, K., Deehan, E. C., Walter, J. & Backhed, F., 2018, In: Cell Host & Microbe. 23, 6, p. 705-715

    Research output: Contribution to journalReviewResearchpeer-review

  23. Published
  24. Published

    GSK3 is a negative regulator of the thermogenic program in brown adipocytes

    Markussen, L. K., Winther, Sally, Wicksteed, B. & Hansen, Jacob B., 2018, In: Scientific Reports. 8, p. 1-12 3469.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    L cell secretory responses after gastric bypass surgery can be imitated in un-operated individuals by modulating carbohydrate digestion

    Martinussen, C., Bojsen-Moller, K. N., Dirksen, C., Svane, M. S., Holst, Jens Juul & Madsbad, Sten, 2018, In: Diabetologia. 61, S1, p. S124-S125 244.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  26. Published

    Benchmarking the HLA typing performance of Polysolver and Optitype in 50 Danish parental trios

    Matey-Hernandez, M. L., Danish Pan Genome Consortium, D. P. G. C., Brunak, Søren, Izarzugaza, J. M. G., Sørensen, L. M., Petersen, Bent, Sibbesen, Jonas Andreas, Liu, S., Belling, K. G., Have, C. T., Bork-Jensen, J., Sun, J., Hansen, Torben, Krogh, Anders, Sørensen, Thorkild I.A., Pedersen, Oluf Borbye, Wang, J., Eiberg, Hans Rudolf Lytchoff & Kristiansen, Karsten, 2018, In: BMC Bioinformatics. 19, p. 1-12 239.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Methodology for Accurate Detection of Mitochondrial DNA Methylation

    Mechta, Mie, Ingerslev, L. R. & Barrès, Romain, 2018, In: Journal of Visualized Experiments. 135, e57772.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Translating biased signaling in the ghrelin receptor system into differential in vivo functions

    Mende, F., Johnsen, Cecilie Hundahl, Plouffe, B., Skov, Louise Julie, Sivertsen, B., Madsen, A. N., Lückmann, Michael, Diep, T. A., Offermanns, S., Frimurer, Thomas Michael, Bouvier, M. & Holst, Birgitte, 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 43, p. E10255-E10264 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    No changes in levels of bone formation and resorption markers following a broad-spectrum antibiotic course

    Mikkelsen, K. H., Vilsbøll, Tina, Holst, Jens Juul, Hartmann, Bolette, Knop, Filip Krag & Frost, M., 2018, In: BMC Endocrine Disorders. 18, 6 p., 60.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Structural changes at the myrtenol backbone reverse its positive allosteric potential into inhibitory GABAA receptor modulation

    Milanos, S., Kuenzel, K., Gilbert, D. F., Janzen, D., Sasi, M., Buettner, A., Frimurer, Thomas Michael & Villmann, C., 2018, In: Biological Chemistry. 399, 6, p. 549-563 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Specific synbiotics in early life protect against diet-induced obesity in adult mice

    Mischke, M., Arora, Tulika, Tims, S., Engels, E., Sommer, N., van Limpt, K., Baars, A., Oozeer, R., Oosting, A., Bäckhed, F. & Knol, J., 2018, In: Diabetes, Obesity and Metabolism. 20, 6, p. 1408-1418 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Metabolite ratios as potential biomarkers for type 2 diabetes: a DIRECT study

    Molnos, S., Wahl, S., Haid, M., Eekhoff, E. M. W., Pool, R., Floegel, A., Deelen, J., Much, D., Prehn, C., Breier, M., Draisma, H. H., van Leeuwen, N., Simonis-Bik, A. M. C., Jonsson, A., Willemsen, G., Bernigau, W., Wang-Sattler, R., Suhre, K., Peters, A., Thorand, B. & 24 others, Herder, C., Rathmann, W., Roden, M., Gieger, C., Kramer, M. H. H., van Heemst, D., Pedersen, H. K., Gudmundsdottir, V., Schulze, M. B., Pischon, T., de Geus, E. J. C., Boeing, H., Boomsma, D. I., Ziegler, A. G., Slagboom, P. E., Hummel, S., Beekman, M., Grallert, H., Brunak, Søren, McCarthy, M. I., Gupta, R., Pearson, E. R., Adamski, J. & 't Hart, L. M., 2018, In: Diabetologia. 61, 1, p. 117-129 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Breastfeeding and complementary feeding in relation to body mass index and overweight at ages 7 and 11 y: A path analysis within the Danish National Birth Cohort

    Morgen, C. S., Ängquist, Lars, Baker, J. L., Nybo Andersen, Anne-Marie, Sørensen, Thorkild I.A. & Michaelsen, Kim F., 2018, In: American Journal of Clinical Nutrition. 107, 3, p. 313-322 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Prenatal risk factors influencing childhood BMI and overweight independent of birth weight and infancy BMI: a path analysis within the Danish National Birth Cohort

    Morgen, C. S., Ängquist, Lars, Baker, J. L., Andersen, A., Michaelsen, Kim F. & Sørensen, Thorkild I.A., 1 Apr 2018, In: International Journal of Obesity. 42, 4, p. 594-602 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Divergent effects of resistance and endurance exercise on plasma bile acids, FGF19, and FGF21 in humans

    Morville, T., Sahl, Ronni Eg, Trammell, Sam, Svenningsen, J. S., Gillum, M. P., Helge, Jørn Wulff & Clemmensen, Christoffer, 2018, In: JCI Insight. 3, 15, p. 1-13 e122737.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Gut: a key player in the pathogenesis of type 2 diabetes?

    Muscogiuri, G., Balercia, G., Barrea, L., Cignarelli, A., Giorgino, F., Holst, Jens Juul, Laudisio, D., Orio, F., Tirabassi, G. & Colao, A., 2018, In: Critical Reviews in Food Science and Nutrition. 58, 8, p. 1294–1309

    Research output: Contribution to journalReviewResearchpeer-review

  37. Published

    In vivo and ex vivo inflammatory markers of common metabolic phenotypes in humans

    Mærkedahl, R. B., Frøkiær, Hanne, Stenbæk, M. G., Nielsen, C. B., Lind, M. V., Lundtoft, C., Bohr, M. B., Ibrügger, S., Metzdorff, S. B., drb459, drb459, Pedersen, Oluf Borbye & Lauritzen, Lotte, 2018, In: Metabolic Syndrome and Related Disorders. 16, 1, p. 29-39 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Anti-Obesity Therapy: from Rainbow Pills to Polyagonists.

    Müller, T., Clemmensen, Christoffer, Finan, B., DiMarchi, R. & Tschöp, M., Oct 2018, In: Pharmacological Reviews.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Quantitative perfusion assessment of intestinal anastomoses in pigs treated with glucagon-like peptide 2

    Nerup, N., Ring, L. L., Strandby, R. B., Egeland, C., Svendsen, M. B. S., Hasselby, Jane Preuss, Willemoe, G. L., Hartmann, Bolette, Svendsen, Lars Bo & Achiam, Michael Patrick, 2018, In: Langenbeck's Archives of Surgery. 403, 7, p. 881-889

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Age at first birth in women is genetically associated with increased risk of schizophrenia

    Ni, G., Gratten, J., Wray, N. R., Lee, S. H., Ripke, S., Neale, B. M., Corvin, A., Walters, J. T. R., Farh, K. H., Holmans, P. A., Lee, P., Bulik-Sullivan, B., Collier, D. A., Huang, H., Pers, T. H., Agartz, I., Agerbo, E., Albus, M., Alexander, M., Amin, F. & 281 others, Bacanu, S. A., Begemann, M., Belliveau, R. A., Bene, J., Bergen, S. E., Bevilacqua, E., Bigdeli, T. B., Black, D. W., Bruggeman, R., Buccola, N. G., Buckner, R. L., Byerley, W., Cahn, W., Cai, G., Campion, D., Cantor, R. M., Carr, V. J., Carrera, N., Catts, S. V., Chambert, K. D., Chan, R. C. K., Chen, R. Y. L., Chen, E. Y. H., Cheng, W., Cheung, E. F. C., Chong, S. A., Cloninger, C. R., Cohen, D., Cohen, N., Cormican, P., Craddock, N., Crowley, J. J., Curtis, D., Davidson, M., Davis, K. L., Degenhardt, F., Del Favero, J., Demontis, D., Dikeos, D., Dinan, T., Djurovic, S., Donohoe, G., Drapeau, E., Duan, J., Dudbridge, F., Durmishi, N., Eichhammer, P., Eriksson, J., Escott-Price, V., Essioux, L., Fanous, A. H., Farrell, M. S., Frank, J., Franke, L., Freedman, R., Freimer, N. B., Friedl, M., Friedman, J. I., Fromer, M., Genovese, G., Georgieva, L., Giegling, I., Giusti-Rodríguez, P., Godard, S., Goldstein, J. I., Golimbet, V., Gopal, S., Haan, L. D., Hammer, C., Hamshere, M. L., Hansen, M., Hansen, Thomas Folkmann, Haroutunian, V., Hartmann, A. M., Henskens, F. A., Herms, S., Hirschhorn, J. N., Hoffmann, P., Hofman, A., Hollegaard, M. V., Hougaard, D. M., Ikeda, M., Joa, I., Juliá, A., Kahn, R. S., Kalaydjieva, L., Karachanak-Yankova, S., Karjalainen, J., Kavanagh, D., Keller, M. C., Kennedy, J. L., Khrunin, A., Kim, Y., Klovins, J., Knowles, J. A., Konte, B., Kucinskas, V., Kucinskiene, Z. A., Kuzelova-Ptackova, H., Kähler, A. K., Laurent, C., Keong, J. L. C., Legge, S. E., Lerer, B., Li, M., Li, T., Liang, K. Y., Lieberman, J., Limborska, S., Loughland, C. M., Lubinski, J., Lönnqvist, J., Macek, M., Magnusson, P. K. E., Maher, B. S., Maier, W., Mallet, J., Marsal, S., Mattheisen, M., Mattingsdal, M., McCarley, R. W., McDonald, C., McIntosh, A. M., Meier, S., Meijer, C. J., Melegh, B., Melle, I., Mesholam-Gately, R. I., Metspalu, A., Michie, P. T., Milani, L., Milanova, V., Mokrab, Y., Morris, D. W., Mors, O., Murphy, K. C., Murray, R. M., Myin-Germeys, I., Müller-Myhsok, B., Nelis, M., Nenadic, I., Nertney, D. A., Nestadt, G., Nicodemus, K. K., Nikitina-Zake, L., Nisenbaum, L., Nordin, A., O'callaghan, E., O'dushlaine, C., O'neill, F. A., Oh, S. Y., Olincy, A., Olsen, L., Os, J. V., Pantelis, C., Papadimitriou, G. N., Papiol, S., Parkhomenko, E., Pato, M. T., Paunio, T., Pejovic-Milovancevic, M., Perkins, D. O., Pietiläinen, O., Pimm, J., Pocklington, A. J., Powell, J., Price, A., Pulver, A. E., Purcell, S. M., Quested, D., Rasmussen, H. B., Reichenberg, A., Reimers, M. A., Richards, A. L., Roffman, J. L., Roussos, P., Ruderfer, D. M., Salomaa, V., Sanders, A. R., Schall, U., Schubert, C. R., Schulze, T. G., Schwab, S. G., Scolnick, E. M., Scott, R. J., Seidman, L. J., Shi, J., Sigurdsson, E., Silagadze, T., Silverman, J. M., Sim, K., Slominsky, P., Smoller, J. W., So, H. C., Spencer, C. C. A., Stahl, E. A., Stefansson, H., Steinberg, S., Stogmann, E., Straub, R. E., Strengman, E., Strohmaier, J., Stroup, T. S., Subramaniam, M., Suvisaari, J., Svrakic, D. M., Szatkiewicz, J. P., Söderman, E., Thirumalai, S., Toncheva, D., Tosato, S., Veijola, J., Waddington, J., Walsh, D., Wang, D., Wang, Q., Webb, B. T., Weiser, M., Wildenauer, D. B., Williams, N. M., Williams, S., Witt, S. H., Wolen, A. R., Wong, E. H. M., Wormley, B. K., Xi, H. S., Zai, C. C., Zheng, X., Zimprich, F., Stefansson, K., Visscher, P. M., Adolfsson, R., Andreassen, O. A., Blackwood, D. H. R., Bramon, E., Buxbaum, J. D., Børglum, A. D., Cichon, S., Darvasi, A., Domenici, E., Ehrenreich, H., Esko, T., Gejman, P. V., Gill, M., Gurling, H., Hultman, C. M., Iwata, N., Jablensky, A. V., Jönsson, E. G., Kendler, K. S., Kirov, G., Knight, J., Lencz, T., Levinson, D. F., Li, Q. S., Liu, J., Malhotra, A. K., McCarroll, S. A., McQuillin, A., Moran, J. L., Mortensen, P. B., Mowry, B. J., Nöthen, M. M., Ophoff, R. A., Owen, M. J., Palotie, A., Pato, C. N., Petryshen, T. L., Posthuma, D., Rietschel, M., Riley, B. P., Rujescu, D., Sham, P. C., Sklar, P., Clair, D. S., Weinberger, D. R., Wendland, J. R., Werge, Thomas, Daly, M. J., Sullivan, P. F. & O'donovan, M. C., 2018, In: Scientific Reports. 8, 1, p. 1-14 10168.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Identification of novel LEPR mutations in Pakistani families with morbid childhood obesity

    Niazi, R. K., Gjesing, A. P., Hollensted, M., Have, C. T., Grarup, N., Pedersen, Oluf Borbye, Ullah, A., Shahid, G., Ahmad, W., Gul, A. & Hansen, Torben, 2018, In: BMC Medical Genetics. 19, 1, p. 1-8 199.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    The effect of diaries written by relatives for intensive care patients on posttraumatic stress (DRIP study): protocol for a randomized controlled trial and mixed methods study

    Nielsen, A. H., Angel, S., Egerod, Ingrid Eugenie & Hansen, Torben, 2018, In: BMC Nursing. 17, p. 1-10 10 p., 37.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    NAMPT-mediated NAD+ biosynthesis is indispensable for adipose tissue plasticity and development of obesity

    Nielsen, K. N., Peics, J., Ma, Tao, Karavaeva, Iuliia, Dall, M., Chubanava, Sabina, Basse, A. L., Dmytriyeva, O., Treebak, Jonas Thue & Gerhart-Hines, Zach, May 2018, In: Molecular Metabolism. 11, p. 178-188 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Hepatitis B virus upregulates host microRNAs that target apoptosis-regulatory genes in an in vitro cell model

    Nielsen, K. O., Jacobsen, K. S., Mirza, A. H., Winther, T. N., Størling, J., Glebe, D., Pociot, Flemming & Høgh, Birthe, 2018, In: Experimental Cell Research. 371, 1, p. 92-103

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Childhood obesity treatment; Effects on BMI SDS, body composition, and fasting plasma lipid concentrations

    Nielsen, T. R. H., Fonvig, Cilius Esmann, Dahl, M., Mollerup, P. M., Lausten-Thomsen, U., Pedersen, Oluf Borbye, Hansen, Torben & Holm, Jens-Christian, 2018, In: P L o S One. 13, 2, p. 1-18 18 p., e0190576.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Lactobacillus reuteri reduces bone loss in older women with low bone mineral density: a randomized, placebo-controlled, double-blind, clinical trial

    Nilsson, A. G., Sundh, D., Backhed, F. & Lorentzon, M., 2018, In: Journal of Internal Medicine. 284, 3, p. 307-317

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    The effect of DPP-4 protected GLP-1 (7-36) on coronary microcirculation in obese adults

    Nilsson, M., Bove, K., Suhrs, E., Hermann, T., Madsbad, Sten, Holst, Jens Juul, Prescott, Eva & Zander, M., 2018, In: Diabetologia. 61, S1, p. S354-S355 729.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  48. Published

    The effect of metformin versus placebo in combination with insulin analogues on bone mineral density and trabecular bone score in patients with type 2 diabetes mellitus: a randomized placebo-controlled trial

    Nordklint, A. K., Almdal, Thomas Peter, Vestergaard, P., Lundby-Christensen, L., Boesgaard, T. W., Breum, Leif, Gade-Rasmussen, B., Sneppen, S. B., Gluud, C., Hemmingsen, B., Jensen, T., Krarup, T., Madsbad, Sten, Mathiesen, Elisabeth, Perrild, Hans, Tarnow, L., Thorsteinsson, B., drb459, drb459, Lund, S. S. & Eiken, P., 2018, In: Osteoporosis International. 29, 11, p. 2517-2526

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Soil bacteria show different tolerance ranges to an unprecedented disturbance

    Nunes, I. M., Jurburg, S., Jacquiod, S. J. A., Brejnrod, A. D., Falcão Salles, J., Priemé, Anders & Sørensen, Søren Johannes, Feb 2018, In: Biology and Fertility of Soils. 54, 2, p. 189–202 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Fasting decreases plasma FGF21 in obese subjects and the expression of FGF21 receptors in adipose tissue in both lean and obese subjects

    Nygaard, E. B., Ørskov, Cathrine, Almdal, Thomas Peter, drb459, drb459 & Andersen, B., 2018, In: Journal of Endocrinology. 239, 1, p. 73-80

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Application of urinary proteomics as possible risk predictor of renal and cardiovascular complications in patients with type 2-diabetes and microalbuminuria

    Oellgaard, J., Gæde, P., Persson, F., Rossing, Peter, Parving, H. & Pedersen, Oluf Borbye, 2018, In: Journal of Diabetes and its Complications. 32, 12, p. 1133-1140

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Reduced risk of heart failure with intensified multifactorial intervention in individuals with type 2 diabetes and microalbuminuria: 21 years of follow-up in the randomised Steno-2 study

    Oellgaard, J., Gaede, P., Rossing, Peter, Rorth, R., Køber, Lars Valeur, Parving, H. & Pedersen, Oluf Borbye, 2018, In: Diabetologia. 61, 8, p. 1724-1733

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    The Intestinotrophic Effects of Glucagon-Like Peptide-2 in Relation to Intestinal Neoplasia

    Orhan, Adile, Gögenur, Ismail & Kissow, Hannelouise, 2018, In: The Journal of clinical endocrinology and metabolism. 103, 8, p. 2827-2837

    Research output: Contribution to journalReviewResearchpeer-review

  54. Published

    Recovery of gut microbiota of healthy adults following antibiotic exposure

    Palleja, A., Mikkelsen, K. H., Forslund, S. K., Kashani, A., Allin, K. H., Nielsen, T., Hansen, T. H., Liang, S., Feng, Q., Zhang, C., Pyl, P. T., Coelho, L. P., Yang, H., Wang, J., Typas, A., Nielsen, M. F., Nielsen, H. B., Bork, P., Wang, J., Vilsbøll, T. & 4 others, Hansen, Torben, Knop, Filip Krag, Arumugam, Mani & Pedersen, Oluf Borbye, Nov 2018, In: Nature Microbiology. 3, 11, p. 1255-1265 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    Exposure to the gut microbiota drives distinct methylome and transcriptome changes in intestinal epithelial cells during postnatal development

    Pan, W., Sommer, F., Falk-Paulsen, M., Ulas, T., Best, P., Fazio, A., Kachroo, P., Luzius, A., Jentzsch, M., Rehman, A., Mueller, F., Lengauer, T., Walter, J., Kuenzel, S., Baines, J. F., Schreiber, S., Franke, A., Schultze, J. L., Backhed, F. & Rosenstiel, P., 2018, In: Genome Medicine. 10, p. 1-15 27.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    Outcome of childhood obesity

    Pedersen, D. C., Sørensen, Thorkild I.A. & Baker, J. L., 2018, Eating Disorders and Obesity in Children and Adolescents. Hebebrand, J. & Herpertz-Dahlmann, B. (eds.). 1 ed. St. Louis, Missouri: Elsevier, p. 165-169 5 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  57. Published

    A computational framework to integrate high-throughput "-omics" datasets for the identification of potential mechanistic links

    Pedersen, H. K., Forslund, S. K., Gudmundsdottir, V., Petersen, A. Ø., Hildebrand, F., Hyötyläinen, T., Nielsen, T., Hansen, Torben, Bork, P., Ehrlich, S. D., Brunak, Søren, Oresic, M., Pedersen, Oluf Borbye & Nielsen, H. B., 2018, In: Nature Protocols. 13, 12, p. 2781-2800 20 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    Identification of protein phosphatase involvement in the AT2 receptor-induced activation of endothelial nitric oxide synthase

    Peluso, A., 2018, In: Clinical Science.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    Hemodynamic Effects of Glucagon: A Literature Review

    Petersen, K. M., Bogevig, S., Holst, Jens Juul, Knop, Filip Krag & Christensen, Mikkel Bring, 2018, In: Journal of Clinical Endocrinology & Metabolism. 103, 5, p. 1804-1812

    Research output: Contribution to journalReviewResearchpeer-review

  60. Published

    Response to Letter to the Editor: "Hemodynamic Effects of Glucagon: A Literature Review"

    Petersen, K. M., Bøgevig, S., Holst, Jens Juul, Knop, Filip Krag & Christensen, Mikkel Bring, 2018, In: The Journal of clinical endocrinology and metabolism. 103, 12, p. 4480-4481 2 p.

    Research output: Contribution to journalComment/debateResearch

  61. Published

    Delayed age at transfer of adoptees to adoptive parents is associated with increased mortality irrespective of social class of the adoptive parents: a cohort study

    Petersen, L., Andersen, Per Kragh, Sørensen, Thorkild I.A. & Mortensen, Erik Lykke, 2018, In: BMC Public Health. 18, 1, 7 p., 435.

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. Published

    Inhibiting RHOA Signaling in Mice Increases Glucose Tolerance and Numbers of Enteroendocrine and Other Secretory Cells in the Intestine

    Petersen, N., Frimurer, Thomas Michael, Pedersen, M. T., Egerod, Kristoffer Lihme, Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Grapin-Botton, A., Jensen, Kim Bak & Schwartz, Thue W., 2018, In: Gastroenterology. 155, 4, p. 1164-1176 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    Obesity is associated with vitamin D deficiency in Danish children and adolescents

    Plesner, J. L., Dahl, M., Fonvig, Cilius Esmann, Nielsen, T. R. H., Kloppenborg, J. T., Pedersen, Oluf Borbye, Hansen, Torben & Holm, Jens-Christian, 26 Jan 2018, In: Journal of Pediatric Endocrinology and Metabolism. 31, 1, p. 53-61 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. Published
  65. Published

    Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6

    Prins, B. P., Mead, T. J., Brody, J. A., Sveinbjornsson, G., Ntalla, I., Bihlmeyer, N. A., van den Berg, M., Bork-Jensen, J., Cappellani, S., Van Duijvenboden, S., Klena, N. T., Gabriel, G. C., Liu, X., Gulec, C., Grarup, N., Haessler, J., Hall, L. M., Iorio, A., Isaacs, A., Li-Gao, R. & 31 others, Lin, H., Liu, C., Lyytikäinen, L., Marten, J., Mei, H., Müller-Nurasyid, M., Orini, M., Padmanabhan, S., Radmanesh, F., Ramirez, J., Robino, A., Schwartz, M., van Setten, J., Smith, A. V., Verweij, N., Warren, H. R., Weiss, S., Alonso, A., Arnar, D. O., Bots, M. L., de Boer, R. A., Dominiczak, A. F., Eijgelsheim, M., Ellinor, P. T., Guo, X., Felix, S. B., Linneberg, Allan René, Pedersen, Oluf Borbye, Hansen, Torben, Kanters, Jørgen K. & et al., E. A., 17 Jul 2018, In: Genome Biology. 19, 17 p., 87.

    Research output: Contribution to journalJournal articleResearchpeer-review

  66. Published

    Distinct signalling properties of insulin receptor substrate (IRS)-1 and IRS-2 in mediating insulin/IGF-1 action

    Rabiee, A., Krüger, M., Ardenkjær-Larsen, J., Ronald Kahn, C. & Emanuelli, Brice, 2018, In: Cellular Signalling. 47, p. 1-15

    Research output: Contribution to journalJournal articleResearchpeer-review

  67. Published

    Effects of Preceding Ethanol Intake on Glucose Response to Low-Dose Glucagon in Individuals With Type 1 Diabetes: A Randomized, Placebo-Controlled, Crossover Study

    Ranjan, A., Nørgaard, Kirsten, Tetzschner, R., Steineck, I. I. K., Clausen, T. R., Holst, Jens Juul, Madsbad, Sten & Schmidt, S., 2018, In: Diabetes Care. 41, 4, p. 797-806

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    Relationship between Optimum Mini‐doses of Glucagon and Insulin Levels when Treating Mild Hypoglycaemia in Patients with Type 1 Diabetes: A Simulation Study

    Ranjan, A., Wendt, S. L., Schmidt, S., Madsbad, Sten, Holst, Jens Juul, Madsen, H., Knudsen, C. B., Jørgensen, J. B. & Nørgaard, Kirsten, 2018, In: Basic & Clinical Pharmacology & Toxicology. 122, 3, p. 322-330

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. Published

    Antibiotic exposure in early life and childhood overweight and obesity: A systematic review and meta-analysis

    Rasmussen, S. H., Shrestha, S., Bjerregaard, L. G., Ängquist, Lars, Baker, J. L., Jess, T. & Allin, K. H., 2018, In: Diabetes, Obesity and Metabolism. 20, 6, p. 1508–1514

    Research output: Contribution to journalReviewResearchpeer-review

  70. Published

    Cholecystokinin secretion is suppressed by glucagon-like peptide-1: clue to the mechanism of the adverse gallbladder events of GLP-1-derived drugs

    Rehfeld, Jens Frederik, Knop, Filip Krag, Asmar, A., Madsbad, Sten, Holst, Jens Juul & Asmar, M., 2018, In: Scandinavian Journal of Gastroenterology. 53, 12, p. 1429-1432

    Research output: Contribution to journalJournal articleResearchpeer-review

  71. Published

    Whole-genome and Transcriptome Sequencing of Prostate Cancer Identify New Genetic Alterations Driving Disease Progression

    Ren, S., Wei, G-H., Liu, D., Wang, L., Hou, Y., Zhu, S., Peng, L., Zhang, Q., Cheng, Y., Su, H., Zhou, X., Zhang, J., Li, F., Zheng, H., Zhao, Z., Yin, C., He, Z., Gao, X., Zhau, H. E., Chu, C-Y. & 42 others, Wu, J. B., Collins, C., Volik, S. V., Bell, R., Huang, J., Wu, K., Xu, D., Ye, D., Yu, Y., Zhu, L., Qiao, M., Lee, H., Yang, Y., Zhu, Y., Shi, X., Chen, R., Wang, Y., Xu, W., Cheng, Y., Xu, C., Gao, X., Zhou, T., Yang, B., Hou, J., Liu, L., Zhang, Z., Zhu, Y., Qin, C., Shao, P., Pang, J., Chung, L. W. K., Xu, J., Wu, C., Zhong, W., Xu, X., Li, Y., Zhang, X., Wang, J., Yang, H., Wang, J., Huang, H. & Sun, Y., 2018, In: European Urology. 73, 3, p. 322-339 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  72. Published

    Structure-Activity Investigations and Optimisations of Non-metabolite Agonists for the Succinate Receptor 1

    Ulven, Elisabeth Rexen, Trauelsen, Mette, Brvar, M., Lückmann, Michael, Bielefeldt, L. Ø., Jensen, L. K. I., Schwartz, Thue W. & Frimurer, Thomas Michael, 2018, In: Scientific Reports. 8, 1, p. 1-18 10010.

    Research output: Contribution to journalJournal articleResearchpeer-review

  73. Published

    Perturbations in the p53/miR-34a/SIRT1 pathway in the R6/2 Huntington's disease model

    Reynolds, R. H., Petersen, M. H., Willert, C. W., Heinrich, M., Nymann, N., Dall, M., Treebak, Jonas Thue, Björkqvist, M., Silahtaroglu, Asli, Hasholt, Lis Frydenreich & Nørremølle, Anne, 2018, In: Molecular and Cellular Neuroscience. 88, p. 118-129

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. Published

    Diagnostik og behandling af maturity onset diabetes of the young type 3

    Rose, K., Christensen, A. S., Storgaard, H., Hædersdal, S., Hansen, Torben, Knop, Filip Krag & Vilsbøll, Tina, 2018, In: Ugeskrift for Laeger. 180, 6 p., V06170502.

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. Published

    Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

    Bipolar Disorder and Schizophrenia Working Group of the Psychiatric Genomics Consortium douglas.ruderfer@vanderbilt.edu, B. D. A. S. W. G. O. T. P. G. C. D. R. E., Psychosis Endophenotypes International Consortium, P. E. I. C. & Wellcome Trust Case-Control Consortium, W. T. C. C., 14 Jun 2018, In: Cell. 173, 7, p. 1705-1715.e16

    Research output: Contribution to journalJournal articleResearchpeer-review

  76. Published

    Effect of metformin on plasma metabolite profile in the Copenhagen Insulin and Metformin Therapy (CIMT) trial

    Safai, N., Suvitaival, T., Ali, A., Spegel, P., Al-Majdoub, M., Carstensen, B., drb459, drb459 & Ridderstråle, M., 2018, In: Diabetic Medicine. 35, 7, p. 944-953

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. Published

    Impact of a multifactorial treatment programme on clinical outcomes and cardiovascular risk estimates: a retrospective cohort study from a specialised diabetes centre in Denmark

    Safai, N., Carstensen, Bendix, drb459, drb459 & Ridderstråle, M., 1 Mar 2018, In: BMJ Open. 8, 3, e019214.

    Research output: Contribution to journalJournal articleResearchpeer-review

  78. Published

    Variation in mitochondrial respiratory capacity and myosin heavy chain composition in repeated muscle biopsies

    Sahl, Ronni Eg, Morville, T., Kraunsøe, R., Dela, Flemming, Helge, Jørn Wulff & Larsen, Steen, 1 Sep 2018, In: Analytical Biochemistry. 556, p. 119-124 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  79. Published

    A carbohydrate-reduced high-protein diet acutely decreases postprandial and diurnal glucose excursions in type 2 diabetes patients

    Samkani, A., fbg982, fbg982, Kandel, D., Kjaer, S., Astrup, A., Deacon, Carolyn F., Holst, Jens Juul, Madsbad, Sten, Rehfeld, Jens Frederik, Haugaard, Steen Bendix & Krarup, T., 2018, In: British Journal of Nutrition. 119, 8, p. 910-917 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  80. Published

    The acute effects of dietary carbohydrate reduction on postprandial responses of non-esterified fatty acids and triglycerides: a randomized trial

    Samkani, A., fbg982, fbg982, Anholm, C., Astrup, A., Deacon, Carolyn F., Holst, Jens Juul, Madsbad, S., Boston, R., Krarup, T. & Haugaard, Steen Bendix, 2018, In: Lipids in Health and Disease. 17, 9 p., 295.

    Research output: Contribution to journalJournal articleResearchpeer-review

  81. Published

    Acute effects of dietary carbohydrate restriction on glycemia, lipemia and appetite regulating hormones in normal-weight to obese subjects

    Samkani, A. A., fbg982, fbg982, Thomsen, M. N., Astrup, A., Deacon, Carolyn F., Holst, Jens Juul, Madsbad, Sten, Rehfeld, Jens Frederik, Krarup, T. & Haugaard, Steen Bendix, 2018, In: Nutrients. 10, 9, 14 p., 1285.

    Research output: Contribution to journalJournal articleResearchpeer-review

  82. Published

    Brown Fat AKT2 Is a Cold-Induced Kinase that Stimulates ChREBP-Mediated De Novo Lipogenesis to Optimize Fuel Storage and Thermogenesis

    Sanchez-Gurmaches, J., Tang, Y., Jespersen, N. Z., Wallace, M., Martinez Calejman, C., Gujja, S., Li, H., Edwards, Y. J. K., Wolfrum, C., Metallo, C. M., Nielsen, S., Schéele, Camilla Charlotte Nielsen & Guertin, D. A., 9 Jan 2018, In: Cell Metabolism. 27, 1, p. 195-209.e6

    Research output: Contribution to journalJournal articleResearchpeer-review

  83. Published

    About this book

    Sandøe, Peter, Jensen, Karsten Klint & Whiteley, Louise, Jan 2018, RCR – A Danish textbook for courses in Responsible Conduct of Research. Jensen, K. K., Whiteley, L. & Sandøe, P. (eds.). 3 ed. Frederiksberg: Department of Food and Resource Economics, University of Copenhagen, p. 8-11 4 p.

    Research output: Chapter in Book/Report/Conference proceedingPreface/postscriptEducation

  84. Published

    Gestational weight gain charts for different body mass index groups for women in Europe, North America, and Oceania

    Santos, S., Eekhout, I., Voerman, E., Gaillard, R., Barros, H., Charles, M-A., Chatzi, L., Chevrier, C., Chrousos, G. P., Corpeleijn, E., Costet, N., Crozier, S., Doyon, M., Eggesbo, M., Fantini, M. P., Farchi, S., Forastiere, F., Gagliardi, L., Georgiu, V., Godfrey, K. M. & 60 others, Gori, D., Grote, V., Hanke, W., Hertz-Picciotto, I., Heude, B., Hivert, M., Hryhorczuk, D., Huang, R., Inskip, H., Jusko, T. A., Karvonen, A. M., Koletzko, B., Kupers, L. K., Lagstrom, H., Lawlor, D. A., Lehmann, I., Lopez-Espinosa, M., Magnus, P., Majewska, R., Makela, J., Manios, Y., McDonald, S. W., Mommers, M., Morgen, C. S., Moschonis, G., Murinova, L., Newnham, J., Nohr, E. A., Nybo Andersen, Anne-Marie, Oken, E., Oostvogels, A. J. J. M., Pac, A., Papadopoulou, E., Pekkanen, J., Pizzi, C., Polanska, K., Porta, D., Richiardi, L., Rifas-Shiman, S. L., Roeleveld, N., Santa-Marina, L., Santos, A. C., Smit, H. A., Sørensen, Thorkild I.A., Standl, M., Stanislawski, M., Stoltenberg, C., Thiering, E., Thijs, C., Torrent, M., Tough, S. C., Trnovec, T., van Gelder, M. M. H. J., van Rossem, L., von Berg, A., Vrijheid, M., Vrijkotte, T. G. M., Zvinchuk, O., van Buuren, S. & Jaddoe, V. W. V., 5 Nov 2018, In: BMC Medicine. 16, 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  85. Published

    Betydning af sædcellens epigenetik for befrugtning og fosterudvikling

    Saupstad, M., Andersen, E. & Barrès, Romain, 2018, In: Ugeskrift for Laeger. 180, p. 2-5 V02180152.

    Research output: Contribution to journalJournal articleResearchpeer-review

  86. Published

    Effects of a diet rich in arabinoxylan and resistant starch compared with a diet rich in refined carbohydrates on postprandial metabolism and features of the metabolic syndrome

    Schioldan, A. G., Gregersen, S., Hald, S., Bjørnshave, A., Bohl, M., Hartmann, Bolette, Holst, Jens Juul, Stødkilde-Jørgensen, H. & Hermansen, K., Mar 2018, In: European Journal of Nutrition. 57, 2, p. 795–807

    Research output: Contribution to journalJournal articleResearchpeer-review

  87. Published

    The effect of casein, hydrolyzed casein, and whey proteins on urinary and postprandial plasma metabolites in overweight and moderately obese human subjects

    Schmedes, M. S., Bendtsen, L. Q., Gomes, S., Liaset, B., Holst, Jens Juul, Ritz, C., Reitelseder, S., Sjödin, Anders Mikael, Astrup, A., Young, J. F., Sundekilde, U. K. & Bertram, H. C., 2018, In: Journal of the Science of Food and Agriculture. 98, 15, p. 5598-5605 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  88. Published

    Genetic predisposition to adiposity is associated with increased objectively assessed sedentary time in young children

    Schnurr, T. M., Viitasalo, A., Eloranta, A., Damsgaard, Camilla Trab, Mahendran, Y., Have, C. T., Väistö, J., Hjorth, Mads Fiil, Christensen, L. B., Brage, S., Atalay, M., Lyytikäinen, L., Lindi, V., Lakka, T., Michaelsen, Kim F., Kilpeläinen, Tuomas O. & Hansen, Torben, 2018, In: International Journal of Obesity. 42, 1, p. 111-114 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  89. Published

    Bifidobacteria or fiber protects against diet-induced microbiota-mediated colonic mucus deterioration

    Schroeder, B. O., Birchenough, G. M. H., Ståhlman, M., Arike, L., Johansson, M. E. V., Hansson, G. C. & Bäckhed, F., 2018, In: Cell Host & Microbe. 23, 1, p. 27-40 + e1-e7 22 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  90. Published

    Proteomics Analysis of Skeletal Muscle from Leptin-Deficient ob/ob Mice Reveals Adaptive Remodeling of Metabolic Characteristics and Fiber Type Composition

    Schönke, M., Björnholm, M., Chibalin, A. V., Zierath, Juleen R & Deshmukh, Atul Shahaji, 2018, In: Proteomics. 18, 5-6, p. 1-11 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  91. Published

    Metabolomic profiling of maternal hair suggests rapid development of intrahepatic cholestasis of pregnancy

    Seymour, J. V. D., Tu, S., He, X., Zhang, H., Han, T., Baker, P. N. & Sulek, K., 2018, In: Metabolomics. 14, 6, p. 1-5 79.

    Research output: Contribution to journalJournal articleResearchpeer-review

  92. Published

    Skeletal muscle O-GlcNAc transferase is important for muscle energy homeostasis and whole-body insulin sensitivity

    Shi, H., Munk, A., Nielsen, T. S., Daughtry, M. R., Larsson, L., Li, S., Høyer, K. F., Geisler, H. W., Sulek, K., Kjøbsted, R., Fisher, T., Andersen, M. M., Shen, Z., Hansen, U. K., England, E. M., Cheng, Z., Højlund, K., Wojtaszewski, J., Yang, X., Hulver, M. W. & 3 others, Helm, R. F., Treebak, Jonas Thue & Gerrard, D. E., 2018, In: Molecular Metabolism. 11, p. 160-177 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  93. Published

    Accurate genotyping across variant classes and lengths using variant graphs

    Sibbesen, Jonas Andreas, Maretty, L., Krogh, Anders, Petersen, Bent, Sibbesen, Jonas Andreas, Liu, S., Have, C. T., Bork-Jensen, J., Guo, X., Hansen, Torben, Krogh, Anders, Sørensen, Thorkild I.A., Pedersen, Oluf Borbye, Wang, J. & Brunak, Søren, 2018, In: Nature Genetics. 50, p. 1054-1059 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  94. Published

    The glucagon like peptide-2 'axis': Capacity for production and response following intestinal resection or repair of gastroschisis in infants

    Sigalet, D. L., Lam, V., Brindle, M., Boctor, D., Wallace, L., de Heuval, E., Hartmann, Bolette & Holst, Jens Juul, 2018, In: Journal of Pediatric Surgery. 53, 5, p. 898-904

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. Published

    Estimating the causal effect of body mass index on hay fever, asthma and lung function using Mendelian randomization

    Skaaby, T., Taylor, A. E., Thuesen, B. H., Jacobsen, R. K., Friedrich, N., Møllehave, L. T., Hansen, S., Larsen, S. C., Völker, U., Nauck, M., Völzke, H., Hansen, Torben, Pedersen, Oluf Borbye, Jørgensen, T., Paternoster, L., Munafò, M., Grarup, N. & Linneberg, Allan René, 2018, In: Allergy. 73, 1, p. 153-164 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  96. Published

    Associations of genetic determinants of serum vitamin B12 and folate concentrations with hay fever and asthma: a Mendelian randomization meta-analysis

    Skaaby, T., Taylor, A. E., Jacobsen, R. K., Møllehave, L. T., Friedrich, N., Thuesen, B. H., Shabanzadeh, D. M., Paternoster, L., Völker, U., Nauck, M., Völzke, H., Munafò, M., Hansen, Torben, Pedersen, Oluf Borbye, Jørgensen, T., Grarup, N. & Linneberg, Allan René, 2018, In: European Journal of Clinical Nutrition. 72, 2, p. 264–271 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  97. Published

    Genetic risk score of insulin resistance risk variants is associated with increased risk of coronary artery disease in patients referred to coronary angiography

    Skals, R. K., Krogager, M. L., Appel, E. V. R., Schnurr, T. M., Have, C. T., Gislason, Gunnar Hilmar, Poulsen, Henrik Enghusen, Køber, Lars Valeur, Engstrøm, Thomas, Stender, S., Hansen, Torben, Grarup, N., Andersson, C., Torp-Pedersen, C. & Weeke, P. E., 2018, In: European Heart Journal. 39, p. 752-753

    Research output: Contribution to journalJournal articleResearchpeer-review

  98. Published

    Separate effects of glucagon like peptide-2 (GLP-2) and glucose-dependent insulinotropic polypeptide (GIP) on bone remodelling

    Skov-Jeppesen, Kirsa, Svane, M., Martinussen, C., Gabe, M., Gasbjerg, Lærke Smidt, Madsbad, Sten, Holst, Jens Juul, Rosenkilde, Mette & Hartmann, Bolette, 2018, In: Diabetologia. 61, S1, p. S245-S245 501.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  99. Published

    Genome-Wide Interactions with Dairy Intake for Body Mass Index in Adults of European Descent

    Smith, C. E., Follis, J. L., Dashti, H. S., Tanaka, T., Graff, M., Fretts, A. M., Kilpeläinen, T. O., Wojczynski, M. K., Richardson, K., Nalls, M. A., Schulz, C-A., Liu, Y., Frazier-Wood, A. C., van Eekelen, E., Wang, C., de Vries, P. S., Mikkilä, V., Rohde, R., Psaty, B. M., Hansen, T. & 43 others, Feitosa, M. F., Lai, C., Houston, D. K., Ferruci, L., Ericson, U., Wang, Z., de Mutsert, R., Oddy, W. H., de Jonge, E. A. L., Seppälä, I., Justice, A. E., Lemaitre, R. N., Sørensen, Thorkild I.A., Province, M. A., Parnell, L. D., Garcia, M. E., Bandinelli, S., Orho-Melander, M., Rich, S. S., Rosendaal, F. R., Pennell, C. E., Kiefte-de Jong, J. C., Kähönen, M., Young, K. L., Pedersen, Oluf Borbye, Aslibekyan, S., Rotter, J. I., Mook-Kanamori, D. O., Zillikens, M. C., Raitakari, O. T., North, K. E., Overvad, K., Arnett, D. K., Hofman, A., Lehtimäki, T., Tjønneland, A., Uitterlinden, A. G., Rivadeneira, F., Franco, O. H., German, J. B., Siscovick, D. S., Cupples, L. A. & Ordovás, J. M., 2018, In: Molecular Nutrition & Food Research. 62, 3, p. 1-12 12 p., 1700347.

    Research output: Contribution to journalJournal articleResearchpeer-review

  100. Published

    Renoprotective effects of dulaglutide in patients with T2DM and CKD

    Sorensen, Charlotte Mehlin & Holst, Jens Juul, 2018, In: Nature Reviews. Nephrology. 14, 11, p. 659-660

    Research output: Contribution to journalComment/debateResearchpeer-review

  101. Published

    Glucose Tolerance Tests and Osteocalcin Responses in Healthy People

    Starup-Linde, J., Westberg-Rasmussen, S., Lykkeboe, S., Handberg, A., Hartmann, Bolette, Holst, Jens Juul, Hermansen, K., Vestergaard, P. & Gregersen, S., 2018, In: Frontiers in Endocrinology. 9

    Research output: Contribution to journalJournal articleResearchpeer-review