- 2020
- Published
ARDD 2020: from aging mechanisms to interventions
Mkrtchyan, G. V., Abdelmohsen, K., Andreux, P., Bagdonaite, I., Barzilai, N., Brunak, S., Cabreiro, F., Cabo, R. D., Campisi, J., Cuervo, A. M., Demaria, M., Ewald, C. Y., Fang, E. F., Faragher, R., Ferrucci, L., Freund, A., Silva-García, C. G., Georgievskaya, A., Gladyshev, V. N., Glass, D. J. & 46 others, , 2020, In: Aging. 12, 24, p. 24486-24503 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
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CCK-1 and CCK-2 receptor agonism do not stimulate GLP-1 and neurotensin secretion in the isolated perfused rat small intestine or GLP-1 and PYY secretion in the rat colon
Modvig, Ida Marie, Christiansen, Charlotte Bayer, Rehfeld, Jens Frederik, Holst, Jens Juul & Veedfald, Simon, 2020, In: Physiological Reports. 8, 2, 8 p., 14352.Research output: Contribution to journal › Journal article › Research › peer-review
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Secretin release after Roux-en-Y gastric bypass reveals a population of glucose-sensitive S cells in distal small intestine
Modvig, Ida Marie, Andersen, Daniel Bjørklund, Grunddal, Kaare Villum, Kuhre, Rune Ehrenreich, Martinussen, C., Christiansen, Charlotte Bayer, Ørskov, Cathrine, Larraufie, P., Kay, R. G., Reimann, F., Gribble, F. M., Hartmann, Bolette, Bojsen-Moller, K. N., Madsbad, Sten, Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, 2020, In: International Journal of Obesity. 44, 9, p. 1859-1871Research output: Contribution to journal › Journal article › Research › peer-review
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Hepatic expression of lipopolysaccharide- binding protein ( Lbp ) is induced by the gut microbiota through Myd88 and impairs glucose tolerance in mice independent of obesity
Molinaro, A., Koh, A., Wu, H., Schoeler, M., Faggi, M. I., Carreras, A., Hallen, A., Backhed, F. & Caesar, R., 2020, In: Molecular Metabolism. 37, 9 p., 100997.Research output: Contribution to journal › Journal article › Research › peer-review
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Imidazole propionate is increased in diabetes and associated with dietary patterns and altered microbial ecology
Molinaro, A., Bel Lassen, P., Henricsson, M., Wu, H., Adriouch, S., Belda, E., Chakaroun, R., Nielsen, T., Bergh, P-O., Rouault, C., Andre, S., Marquet, F., Andreelli, F., Salem, J-E., Assmann, K., Bastard, J-P., Forslund, S., Le Chatelier, E., Falony, G., Pons, N. & 26 others, , 2020, In: Nature Communications. 11, 1, 10 p., 5881.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Plasma Metabolome Profiling of Resistance Exercise and Endurance Exercise in Humans
Morville, T., Sahl, Ronni Eg, Moritz, Thomas, Helge, Jørn Wulff & Clemmensen, Christoffer, 2020, In: Cell Reports. 33, 13, 14 p., 108554.Research output: Contribution to journal › Journal article › Research › peer-review
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Effect of wheat bran derived prebiotic supplementation on gastrointestinal transit, gut microbiota, and metabolic health: a randomized controlled trial in healthy adults with a slow gut transit
Muller, M., Hermes, G. D. A., Canfora, E. E., Holst, Jens Juul, Zoetendal, E. G., Smidt, H., Troost, F., Schaap, F. G., Damink, S. O., Jocken, J. W. E., Lenaerts, K., Masclee, A. A. M. & Blaak, E. E., 2020, In: Gut Microbes. 12, 1, 15 p., e1704141.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cytoplasmic Citrate Flux Modulates the Immune Stimulatory NKG2D Ligand MICA in Cancer Cells
Møller, S. H., Mellergaard, M., Madsen, M., Bermejo, A. V., Jepsen, Stine Dam, Hansen, M. H., Høgh, R. I., Aldana, Blanca, Desler, Claus, Rasmussen, Lene Juel, Sustarsic, E. G., Gerhart-Hines, Zach, Daskalaki, E., Wheelock, C. E., Hiron, T. K., Lin, D., O'Callaghan, C. A., Wandall, Hans H., Andresen, Lars & Skov, Søren, 2020, In: Frontiers in Immunology. 11, 22 p., 1968.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pathophysiological-based treatments of complications of cirrhosis
Møller, Søren, Kimer, N., Barløse, Mads Christian Johannes & Bendtsen, Flemming, 2020, In: Scandinavian Journal of Gastroenterology. 55, 4, p. 383-394Research output: Contribution to journal › Review › Research › peer-review
- Published
Community-intrinsic properties enhance keratin degradation from bacterial consortia
Nasipuri, P., Herschend, J., Brejnrod, A. D., Madsen, Jonas Stenløkke, Espersen, R., Svensson, B., Burmølle, Mette, Jacquiod, S. & Sørensen, Søren Johannes, 2020, In: PLoS ONE. 15, 1, 26 p., e0228108.Research output: Contribution to journal › Journal article › Research › peer-review
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No evidence of tachyphylaxis for insulinotropic actions of glucose-dependent insulinotropic polypeptide (GIP) in subjects with type 2 diabetes, their first-degree relatives, or in healthy subjects
Nauck, M. A., Holle, H., Kahle, M., Tytko, A., Deacon, Carolyn F., Holst, Jens Juul & Meier, J. J., 2020, In: Peptides. 125, 170176.Research output: Contribution to journal › Review › Research › peer-review
- Published
Thyroid hormone receptor α in skeletal muscle is essential for T3-mediated increase in energy expenditure
Nicolaisen, T. S., Klein, A. B., Dmytriyeva, O., Lund, Jens, Ingerslev, L. R., Fritzen, Andreas Mæchel, Carl, Christian Strini, Lundsgaard, Anne-Marie, Frost, M., Ma, Tao, Schjerling, P., Gerhart-Hines, Zach, Flamant, F., Gauthier, K., Larsen, Steen, Richter, Erik A., Kiens, Bente & Clemmensen, Christoffer, 2020, In: F A S E B Journal. 34, 11, p. 15480-15491 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Selective inhibitors of SIRT2 regulate perinuclear α-tubulin acetylation, migration, and invasion of breast cancer cells
Nielsen, A. L., Rajabi, N., Kudo, N., Jørgensen, Kathrine Lundø, Fontenas, M., Lucidi, A., Madsen, A. S., Yoshida, M. & Olsen, Christian Adam, 2020, In: bioRxiv. 26 p.Research output: Contribution to journal › Journal article › Research
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Alpha-Lactalbumin Enriched Whey Protein Concentrate to Improve Gut, Immunity and Brain Development in Preterm Pigs
Nielsen, Charlotte Holme, Hui, Y., Nguyen, Duc Ninh, Ahnfeldt, Agnethe May, Burrin, D. G., Hartmann, Bolette, Heckmann, A. B., Sangild, Per Torp, Thymann, Thomas & Bering, S. B., 2020, In: Nutrients. 12, 1, 20 p., 245.Research output: Contribution to journal › Journal article › Research › peer-review
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Oxyntomodulin and glicentin may predict the effect of bariatric surgery on food preferences and weight loss
Nielsen, M. S., Ritz, C., Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, le Roux, C. W. & Sjödin, Anders Mikael, 2020, In: Journal of Clinical Endocrinology and Metabolism. 105, 4, p. e1064-e1074Research output: Contribution to journal › Journal article › Research › peer-review
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Predictors of weight loss after bariatric surgery - a cross-disciplinary approach combining physiological, social, and psychological measures
Nielsen, M. S., Christensen, Bodil Just, Schmidt, J. B., Tækker, L., Holm, Lotte, Lunn, Susanne, Ritz, C., Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Schnurr, T. M., Hansen, Torben, le Roux, C. W., Lund, Thomas Bøker, Floyd, A. K. & Sjödin, Anders Mikael, 2020, In: International Journal of Obesity. 44, 11, p. 2291-2302 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Data integration for prediction of weight loss in randomized controlled dietary trials
Nielsen, R. L., Helenius, M., Garcia, S. L., Roager, H. M., Aytan-Aktug, D., Hansen, L. B. S., Lind, M. V., Vogt, J. K., Dalgaard, M. D., Bahl, M. I., Jensen, C. B., Muktupavela, R., Warinner, C., Aaskov, V., Gøbel, R., Kristensen, M. B., Frøkiær, H., Sparholt, M. H., Christensen, A. F., Vestergaard, H. & 8 others, , 2020, In: Scientific Reports. 10, 15 p., 20103.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ambulant opfølgning og rehabilitering af dekompenseret levercirrose bør være et tværfagligt samarbejde
O'Connell, M. B., Hobolth, L., Teisner, A. S., Andersen, M. L. & Kimer, N., 2020, In: Ugeskrift for Laeger. 182, 13, 8 p., V08190459.Research output: Contribution to journal › Journal article › Research › peer-review
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Post-load glucose subgroups and associated metabolic traits in individuals with type 2 diabetes: An IMI-DIRECT study
Obura, M., Beulens, J. W. J., Slieker, R., Koopman, A. D. M., Hoekstra, T., Nijpels, G., Elders, P., Koivula, R. W., Kurbasic, A., Laakso, M., Hansen, T. H., Ridderstråle, M., Hansen, T., Pavo, I., Forgie, I., Jablonka, B., Ruetten, H., Mari, A., McCarthy, M. I., Walker, M. & 19 others, , 2020, In: PLoS ONE. 15, 11, 11 p., e0242360.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Low Dose of Pasireotide Prevents Hypoglycemia in Roux-en-Y Gastric Bypass-Operated Individuals
Ohrstrom, C. C., Hansen, D. L., Kielgast, U. L., Hartmann, Bolette, Holst, Jens Juul & Worm, Dorte, 2020, In: Obesity Surgery. 30, p. 1605-1610 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gut microbiota of obese subjects with Prader-Willi syndrome is linked to metabolic health
Olsson, L. M., Poitou, C., Tremaroli, V., Coupaye, M., Aron-Wisnewsky, J., Bäckhed, F., Clément, K. & Caesar, R., 2020, In: Gut. 69, 7, 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Body mass index in young adulthood and risk of subsequent dementia at different levels of intelligence and education in Danish men
Osler, Merete, Okholm, Gunhild Tidemann, Sørensen, Thorkild I.A. & Jørgensen, Terese Sara Høj, 2020, In: European Journal of Epidemiology. 35, p. 843–850 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The effect of diabetes and the common diabetogenic TBC1D4 p.Arg684Ter variant on cardiovascular risk in Inuit in Greenland
Overvad, M., Diaz, L. J., Bjerregaard, P., Pedersen, M. L., Larsen, C. V. L., Senftleber, N., Grarup, N., Hansen, Torben & Jørgensen, M. E., 2020, In: Scientific Reports. 10, 9 p., 22081.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Associations of childhood BMI and change in BMI from childhood to adulthood with risks of hypertensive disorders in pregnancy
Pedersen, D. C., Bjerregaard, L. G., Nohr, E. A., Rasmussen, K. M. & Baker, J. L., 2020, In: American Journal of Clinical Nutrition. 112, 5, p. 1180-1187 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Changes and correlations in height from 7 to 69 years of age across the birth years of 1930 to 1989
Pedersen, D. C., Meyle, K. D., Ängquist, Lars, Andersen, Ingelise, Tjønneland, Anne, Linneberg, Allan René, Osler, Merete, Mortensen, Erik Lykke, Gyntelberg, F., Lund, Rikke, Aarestrup, J. & Baker, J. L., 2020, In: American Journal of Human Biology. 32, 4, e23378.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Risk of pancreatitis in patients with inflammatory bowel disease - a meta-analysis
Pedersen, J. E., Ängquist, Lars, Jensen, C. B., Kjærgaard, J. S., Jess, T. & Allin, K. H., 2020, In: Danish Medical Journal. 67, 3, 6 p., A08190427.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dietary sucrose induces metabolic inflammation and atherosclerotic cardiovascular diseases more than dietary fat in LDLr−/− ApoB100/100 mice
Perazza, L. R., Mitchell, P. L., Jensen, Benjamin Anderschou Holbech, Daniel, N., Boyer, M., Varin, T. V., Bouchareb, R., Nachbar, R. T., Bouchard, M., Blais, M., Gagné, A., Joubert, P., Sweeney, G., Roy, D., Arsenault, B. J., Mathieu, P. & Marette, A., 2020, In: Atherosclerosis. 304, p. 9-21 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Different Malabsorptive Obesity Surgery Interventions Result in Distinct Postprandial Amino Acid Metabolomic Signatures
Pereira, S. S., Jarak, I., Carvalho, R. A., Oliveira, P. F., Alves, M. G., Guimaraes, M., Almeida, R., Pereira, A. M., Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Nora, M. & Monteiro, M. P., 2020, In: Obesity Surgery. 30, p. 4019-4028Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cardiovascular effects of high-dose glucagon: a randomised clinical trial
Petersen, K. M., Bogevig, S., Riis, T., Andersson, N. A. W., Dalhoff, Kim, Holst, Jens Juul, Knop, Filip Krag, Faber, Jens, Petersen, Tonny Studsgaard & Christensen, Mikkel Bring, 2020, In: Diabetologia. 63, SUPPL 1, p. S231-S231Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
High-Dose Glucagon Has Hemodynamic Effects Regardless of Cardiac Beta-Adrenoceptor Blockade: A Randomized Clinical Trial
Petersen, K. M., Bøgevig, S., Riis, T., Andersson, N. W., Dalhoff, Kim, Holst, Jens Juul, Knop, Filip Krag, Faber, Jens, Petersen, Tonny Studsgaard & Christensen, Mikkel Bring, 2020, In: Journal of the American Heart Association. 9, 21, 27 p., e016828.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Three-Dimensional Explant Platform for Studies on Choroid Plexus Epithelium
Petersen, N., Pedersen, Lola Julie Torz, Jensen, Kristian HR, Hjortø, Gertrud Malene, Spiess, Katja & Rosenkilde, Mette, 2020, In: Frontiers in Cellular Neuroscience. 14, 11 p., 108.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of epilepsy-associated neuronal subtypes and gene expression underlying epileptogenesis: [incl. Author Correction]
Pfisterer, U., Petukhov, V., Demharter, S., Meichsner, J., Thompson, J. J., Batiuk, M. Y., Martinez, A. A., Vasistha, Navneet A, Thakur, A., Mikkelsen, Jens D., Adorjan, I., Pinborg, Lars Hageman, Pers, Tune H, von Engelhardt, J., Kharchenko, P. V. & Khodosevich, K., 2020, In: Nature Communications. 11, 1, 19 p., 5038.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Changes in parental smoking during pregnancy and risks of adverse birth outcomes and childhood overweight in Europe and North America: An individual participant data meta-analysis of 229,000 singleton births
Philips, E. M., Santos, S., Trasande, L., Aurrekoetxea, J. J., Barros, H., von Berg, A., Bergström, A., Bird, P. K., Brescianini, S., Chaoimh, C. N., Charles, M-A., Chatzi, L., Chevrier, C., Chrousos, G. P., Costet, N., Criswell, R., Crozier, S., Eggesbo, M., Fantini, M. P., Farchi, S. & 48 others, , 2020, In: PLoS Medicine. 17, 8, 25 p., e1003182.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Butyrate producing colonic Clostridiales metabolise human milk oligosaccharides and cross feed on mucin via conserved pathways
Pichler, M. J., Yamada, C., Shuoker, B., Alvarez Silva, Maria Camila, Gotoh, A., Leth, M. L., Schoof, E., Katoh, T., Sakanaka, M., Katayama, T., Jin, C., Karlsson, N. G., Arumugam, Mani, Fushinobu, S. & Abou Hachem, M., 2020, In: Nature Communications. 11, 15 p., 3285.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transcriptomic profiling of skeletal muscle adaptations to exercise and inactivity
Pillon, N. J., Gabriel, B. M., Dollet, L., Smith, J. A. B., Puig, L. S., Botella, J., Bishop, D. J., Krook, A. & Zierath, Juleen R, 2020, In: Nature Communications. 11, 1, 15 p., 470.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Calsyntenin 3β Is Dynamically Regulated by Temperature in Murine Brown Adipose and Marks Human Multilocular Fat
Plucinska, Kaja, Jespersen, N. Z., Brown, E. L., Petersen, P. S., Rupar, K., Nielsen, S., Schéele, Camilla Charlotte Nielsen & Emanuelli, Brice, 2020, In: Frontiers in Endocrinology. 11, 7 p., 579785.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of obesity, weight loss, and free fatty acids on skeletal muscle clock gene expression
Puig, L. S., Pillon, N. J., Naslund, E., Krook, A. & Zierath, Juleen R, 2020, In: American Journal of Physiology: Endocrinology and Metabolism. 318, 1, p. E1-E10 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Protocol for a single-centre, parallel-group, randomised, controlled, superiority trial on the effects of time-restricted eating on body weight, behaviour and metabolism in individuals at high risk of type 2 diabetes: the REStricted Eating Time (RESET) study
Quist, Jonas Salling, Jensen, M. M., Clemmensen, K. K. B., Pedersen, H., Bjerre, N., Størling, Joachim, Blond, M. B., Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Torekov, Signe Sørensen, Vistisen, D., Jørgensen, M. E., Panda, S., Brock, C., Finlayson, G. & Faerch, K., 2020, In: BMJ Open. 10, 8, 11 p., 037166.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ecological succession in the vaginal microbiota during pregnancy and birth
Rasmussen, Morten Arendt, Thorsen, Jonathan Jan Ilve, Dominguez-Bello, M. G., Blaser, M. J., Mortensen, M. S., Brejnrod, A. D., Shah, S. A., Hjelmsø, M. H., Lehtimäki, J., Trivedi, Urvish, Bisgaard, H., Sørensen, Søren Johannes & Stokholm, Jakob, 2020, In: The ISME Journal. 14, 9, p. 2325-2335 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Housing temperature influences exercise training adaptations in mice
Raun, Steffen Henning, Henriquez-Olguín, Carlos, Karavaeva, Iuliia, Ali, Mona Sadek, Møller, Lisbeth L V, Kot, Witold, Castro-Mejía, J. L., Nielsen, Dennis Sandris, Gerhart-Hines, Zach, Richter, Erik A. & Sylow, Lykke, 2020, In: Nature Communications. 11, 16 p., 1560.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Adverse labour market impacts of childhood and adolescence overweight and obesity in Western societies-A literature review
Reiband, H. K., Heitmann, Berit & Sørensen, Thorkild I.A., 2020, In: Obesity Reviews. 21, 8, e13026.Research output: Contribution to journal › Review › Research › peer-review
- Published
Modeling neural tube development by differentiation of human embryonic stem cells in a microfluidic WNT gradient
Rifes, P., Isaksson, M., Rathore, Gaurav Singh, Aldrin-Kirk, P., Moller, O. K., Barzaghi, G., Lee, J., Egerod, Kristoffer Lihme, Belmont-Rausch, Dylan Matthew, Parmar, M., Pers, Tune H, Laurell, T. & Kirkeby, Agnete, 2020, In: Nature Biotechnology. 38, p. 1265-1273 9 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Predictive Metagenomic Analysis Reveals a Role of Cutaneous Dysbiosis in the Development of Hidradenitis Suppurativa
Ring, H. C., Thorsen, Jonathan Jan Ilve, Jørgensen, A. H., Bay, Lene, Bjarnsholt, Thomas, Fuursted, K., Thomsen, Simon Francis & Jemec, Gregor, 2020, In: Journal of Investigative Dermatology. 140, 7, p. 1473-1476Research output: Contribution to journal › Letter › Research › peer-review
- Published
Oral D/L-3-Hydroxybutyrate Stimulates Cholecystokinin and Insulin Secretion and Slows Gastric Emptying in Healthy Males
Rittig, N., Svart, M., Thomsen, H. H., Vestergaard, E. T., Rehfeld, Jens Frederik, Hartmann, Bolette, Holst, Jens Juul, Johannsen, M., Møller, N. & Jessen, N., 2020, In: Journal of Clinical Endocrinology and Metabolism. 105, 10, 9 p., dgaa483.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Abdominal visceral and subcutaneous adipose tissue and associations with cardiometabolic risk in Inuit, Africans and Europeans: a cross-sectional study
Rønn, P. F., Andersen, G. S., Lauritzen, T., Christensen, Dirk Lund, Aadahl, Mette, Carstensen, Bendix, Grarup, N. & Jørgensen, M. E., 14 Sep 2020, In: BMJ Open. 10, 9, 11 p., e038071.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Use of inhaled corticosteroids and the risk of developing type 2 diabetes in patients with chronic obstructive pulmonary disease
Saeed, M. I., Eklof, J., Achir, I., Sivapalan, P., Meteran, Howraman, Lokke, A., Biering-Sørensen, Tor, Knop, Filip Krag & Jensen , Jens-Ulrik Stæhr , 2020, In: Diabetes, Obesity and Metabolism. 22, 8, p. 1348-1356 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ProAlanase is an Effective Alternative to Trypsin for Proteomics Applications and Disulfide Bond Mapping
Samodova, D., Hosfield, C. M., Cramer, C. N., Giuli, M. V., Cappellini, Enrico, Franciosa, Giulia, Rosenblatt, M. M., Kelstrup, C. D. & Olsen, Jesper Velgaard, 2020, In: Molecular & Cellular Proteomics. 19, 12, 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cerebral small vessel disease genomics and its implications across the lifespan
Sargurupremraj, M., Suzuki, H., Jian, X., Sarnowski, C., Evans, T. E., Bis, J. C., Eiriksdottir, G., Sakaue, S., Terzikhan, N., Habes, M., Zhao, W., Armstrong, N. J., Hofer, E., Yanek, L. R., Hagenaars, S. P., Kumar, R. B., van den Akker, E. B., McWhirter, R. E., Trompet, S., Mishra, A. & 32 others, , 2020, In: Nature Communications. 11, 1, 18 p., 6285.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Secretion of parathyroid hormone may be coupled to insulin secretion in humans
Sass, M. R., Albrechtsen, Nicolai Jacob Wewer, Pedersen, Jens, Hare, Kristine Juul, Borbye-Lorenzen, N., Kiss, K., Vilsbøll, Tina, Knop, Filip Krag, Poulsen, Steen Seier, Jørgensen, Niklas Rye, Holst, Jens Juul, Ørskov, Cathrine & Hartmann, Bolette, 2020, In: Endocrine Connections. 9, 7, p. 747-754Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Train like an athlete: applying exercise interventions to manage type 2 diabetes
Savikj, M. & Zierath, Juleen R, 2020, In: Diabetologia. 63, 8, p. 1491-1499Research output: Contribution to journal › Review › Research › peer-review
- Published
Brown Adipose Crosstalk in Tissue Plasticity and Human Metabolism
Schéele, Camilla Charlotte Nielsen & Wolfrum, C., 2020, In: Endocrine Reviews. 41, 1, p. 53-65Research output: Contribution to journal › Review › Research › peer-review
- Published
Trust is good, control is better: technical considerations in blood microbiome analysis
Schierwagen, R., Alvarez Silva, Maria Camila, Servant, F., Trebicka, J., Lelouvier, B. & Arumugam, Mani, 2020, In: Gut. 69, 7, p. 1362-1363Research output: Contribution to journal › Letter › Research › peer-review
- Published
Obesity, unfavourable lifestyle and genetic risk of type 2 diabetes: a case-cohort study
Schnurr, T. M., Jakupovic, Hermina, Carrasquilla, Germán D., Ängquist, Lars, Grarup, N., Sørensen, Thorkild I.A., Tjønneland, Anne, Overvad, K., Pedersen, Oluf Borbye, Hansen, Torben & Kilpeläinen, Tuomas O., 2020, In: Diabetologia. 63, 7, p. 1324-1332 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The influence of transmitted and non-transmitted parental BMI-associated alleles on the risk of overweight in childhood
Schnurr, T. M., Morgen, C. S., Borisevich, D., Beaumont, R. N., pjx571, pjx571, Ängquist, Lars, Have, C. T., Freathy, R. M., Smith, G. D., Nohr, E. A., Hansen, Torben & Sørensen, Thorkild I.A., 2020, In: Scientific Reports. 10, 1, 10 p., 4806.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Obesity-associated microbiota contributes to mucus layer defects in genetically obese mice
Schroeder, B. O., Birchenough, G. M. H., Pradhan, M., Nystrom, E. E. L., Henricsson, M., Hansson, G. C. & Backhed, F., 2020, In: Journal of Biological Chemistry. 295, 46, p. 15712-15726 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Acute Effects of Three Different Meal Patterns on Postprandial Metabolism in Older Individuals with a Risk Phenotype for Cardiometabolic Diseases: A Randomized Controlled Crossover Trial
Schönknecht, Y. B., Crommen, S., Stoffel-Wagner, B., Coenen, M., Fimmers, R., Holst, Jens Juul, Simon, M. C., Stehle, P. & Egert, S., 2020, In: Molecular Nutrition & Food Research. 64, 9, 13 p., 1901035.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Renlighed
Scott-Fordsmand, Helene, Whiteley, Louise & Friis, Tine, Sep 2020Research output: Other contribution › Net publication - Internet publication › Communication
- Published
Genetic study of the Arctic CPT1A variant suggests that its effect on fatty acid levels is modulated by traditional Inuit diet
Senftleber, N., Jørgensen, M. E., Jørsboe, E., Imamura, F., Forouhi, N. G., Larsen, C. L., Bjerregaard, P., Hansen, Torben & Albrechtsen, Anders, 2020, In: European Journal of Human Genetics. 28, 11, p. 1592-1601 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Exercise and browning of white adipose tissue - a translational perspective
Severinsen, M. C. K., Schéele, Camilla Charlotte Nielsen & Pedersen, Bente Klarlund, 2020, In: Current Opinion in Pharmacology. 52, p. 18-24 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Muscle-Organ Crosstalk: The Emerging Roles of Myokines
Severinsen, M. C. K. & Pedersen, Bente Klarlund, 2020, In: Endocrine Reviews. 41, 4, p. 594-609Research output: Contribution to journal › Review › Research › peer-review
- Published
Effects of Gender-Affirming Hormone Therapy on Insulin Sensitivity and Incretin Responses in Transgender People
Shadid, S., Abosi-Appeadu, K., De Maertelaere, A., Defreyne, J., Veldeman, L., Holst, Jens Juul, Lapauw, B., Vilsbøll, Tina & T'Sjoen, G., 2020, In: Diabetes Care. 43, 2, p. 411-417Research output: Contribution to journal › Journal article › Research › peer-review
- Published
FGF6 and FGF9 regulate UCP1 expression independent of brown adipogenesis
Shamsi, F., Xue, R., Huang, T. L., Lundh, M., Liu, Y., Leiria, L. O., Lynes, M. D., Kempf, E., Wang, C. H., Sugimoto, S., Nigro, P., Landgraf, K., Schulz, T., Li, Y., Emanuelli, B., Kothakota, S., Williams, L. T., Jessen, N., Pedersen, S. B., Böttcher, Y. & 6 others, , 2020, In: Nature Communications. 11, 1, 16 p., 1421.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic and environmental variation in educational attainment: an individual-based analysis of 28 twin cohorts
Silventoinen, K., Jelenkovic, A., Sund, R., Latvala, A., Honda, C., Inui, F., Tomizawa, R., Watanabe, M., Sakai, N., Rebato, E., Busjahn, A., Tyler, J., Hopper, J. L., Ordoñana, J. R., Sánchez-Romera, J. F., Colodro-Conde, L., Calais-Ferreira, L., Oliveira, V. C., Ferreira, P. H., Medda, E. & 55 others, , 2020, In: Scientific Reports. 10, 1, 11 p., 12681.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Distinct alterations of gut morphology and microbiota characterize accelerated diabetes onset in nonobese diabetic mice
Simon, M., Reinbeck, A. L., Wessel, C., Heindirk, J., Jelenik, T., Kaul, K., Arreguin-Cano, J., Strom, A., Blaut, M., Backhed, F., Burkart, V. & Roden, M., 2020, In: Journal of Biological Chemistry. 295, 4, p. 969-980 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of a highly controlled carbohydrate-reduced high-protein diet on markers of oxidatively generated nucleic acid modifications and inflammation in weight stable participants with type 2 diabetes: a randomized controlled trial
Skytte, M. J., Samkani, A., Astrup, A., Larsen, T. M., Frystyk, J., Poulsen, Henrik Enghusen, Henriksen, T., Holst, Jens Juul, Andersen, Ove, Madsbad, Sten, Haugaard, Steen Bendix, Krarup, T. & Larsen, E. L., 2020, In: Scandinavian Journal of Clinical & Laboratory Investigation. 80, 5, p. 401-407 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Contraction influences Per2 gene expression in skeletal muscle through a calcium-dependent pathway
Small, Lewin Barkla, Altıntaş, Ali, Laker, R. C., Ehrlich, Amy M, Pattamaprapanont, P., Villarroel, J., Pillon, N. J., Zierath, Juleen R & Barrès, Romain, 2020, In: The Journal of Physiology. 598, 24, p. 5739-5752Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GIP and the gut-bone axis – Physiological, pathophysiological and potential therapeutic implications
Stensen, S., Gasbjerg, Lærke Smidt, Helsted, M. M., Hartmann, Bolette, Christensen, Mikkel Bring & Knop, Filip Krag, 2020, In: Peptides. 125, 7 p., 170197.Research output: Contribution to journal › Review › Research › peer-review
- Published
snRNA-seq reveals a subpopulation of adipocytes that regulates thermogenesis
Sun, W., Dong, H., Balaz, M., Slyper, M., Drokhlyansky, E., Colleluori, G., Giordano, A., Kovanicova, Z., Stefanicka, P., Balazova, L., Ding, L., Husted, Anna Sofie, Rudofsky, G., Ukropec, J., Cinti, S., Schwartz, Thue W., Regev, A. & Wolfrum, C., 2020, In: Nature. 587, 31 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon Resistance at the Level of Amino Acid Turnover in Obese Subjects With Hepatic Steatosis
Suppli, M. P., Bagger, J. I., Lund, A., Demant, M., van Hall, Gerrit, Strandberg, C., Kønig, M. J., Rigbolt, K., Langhoff, J. L., Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2020, In: Diabetes. 69, 6, p. 1090-1099 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals
Surendran, P., Feofanova, E. V., Lahrouchi, N., Ntalla, I., Karthikeyan, S., Cook, J., Chen, L., Mifsud, B., Yao, C., Kraja, A. T., Cartwright, J. H., Hellwege, J. N., Giri, A., Tragante, V., Thorleifsson, G., Liu, D. J., Prins, B. P., Stewart, I. D., Cabrera, C. P., Eales, J. M. & 34 others, , 2020, In: Nature Genetics. 52, 12, p. 1314-1332 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of a six-week intervention with glucagon-like peptide-1 receptor analogue on pancreatic volume, oedema and DNA synthesis in obese men
Svane, M. S., Johannesen, Helle Hjorth, Martinussen, C., Bojsen-Moller, K. N., Hansen, M. L., Hansen, A. E., Deacon, Carolyn F., Hartmann, Bolette, Keller, S. H., Loft, A., Kjær, Andreas, Madsbad, Sten, Lofgren, J., Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2020, In: Diabetologia. 63, SUPPL 1, p. S216-S217 442.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
No effects of a 6-week intervention with a glucagon-like peptide-1 receptor agonist on pancreatic volume and oedema in obese men without diabetes
Svane, M. S., Johannesen, Helle Hjorth, Martinussen, C., Bojsen-Moller, K. N., Hansen, M. L., Hansen, Adam Espe, Deacon, Carolyn F., Hartmann, Bolette, Keller, S. H., Klausen, T. L., Loft, A., Kjær, Andreas, Madsbad, Sten, Lofgren, J., Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2020, In: Diabetes, Obesity and Metabolism. 22, 10, p. 1837-1846Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Alterations in blood microbiota after colonic cancer surgery
Søby, J. H., Watt, S. K., Vogelsang, R. P., Servant, F., Lelouvier, B., Raskov, H., Knop, Filip Krag & Gögenur, Ismail, 2020, In: BJS open. 4, 6, p. 1227-1237Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Relationship between biochemical and symptomatic hypoglycemia after RYGB. Responses to a mixed meal test: a case-control study
Søeby, M., Nielsen, J. B., Pedersen, S. B., Gribsholt, S. B., Holst, Jens Juul & Richelsen, B., 2020, In: Surgery for Obesity and Related Diseases. 16, 9, p. 1179-1185 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The intestinal microbiome is a co-determinant of the postprandial plasma glucose response
Søndertoft, N. B., Vogt, J. K., Arumugam, Mani, Kristensen, M., Gøbel, R. J., Fan, Yong, Lyu, Liwei, Bahl, M. I., Eriksen, C., Ängquist, Lars, Frøkiær, Hanne, Hansen, T. H., Brix, Susanne, Nielsen, H. B., Hansen, Torben, Vestergaard, H., Gupta, R., Licht, T. R., Lauritzen, Lotte & Pedersen, Oluf Borbye, 2020, In: P L o S One. 15, 9, 23 p., e0238648.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Beating tissue factor at its own game: Design and properties of a soluble tissue factor - independent coagulation factor VIIa
Sørensen, A. B., Tuneew, I., Svensson, L. A., Persson, E., Ostergaard, H., Overgaard, M. T., Olsen, O. H. & Gandhi, P. S., 2020, In: Journal of Biological Chemistry. 295, 2, p. 517-528Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Early life body size and its associations with adult bladder cancer
Sørensen, K. K., Jensen, B. W., Thomas, P. E., Madsen, K., Eriksson, Frank, Aarestrup, J. & Baker, J. L., 2020, In: Annals of Human Biology. 47, 2, p. 166-172 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exposure to traffic noise and gestational weight gain and postpartum weight retention: a cohort study
Sørensen, M., Sørensen, Thorkild I.A., Ketzel, M. & Raaschou-Nielsen, O., 2020, In: Occupational and Environmental Medicine. 77, 2, p. 107-114 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Levels and changes in body mass index decomposed into fat and fat-free mass index: relation to long-term all-cause mortality in the general population
Sørensen, Thorkild I.A., Frederiksen, P. & Heitmann, Berit, 2020, In: International Journal of Obesity. 44, p. 2092–2100 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Activation of metabolite receptor GPR91 promotes platelet aggregation and transcellular biosynthesis of leukotriene C4
Tang, X., Fuchs, D., Tan, S., Trauelsen, Mette, Schwartz, Thue W., Wheelock, C. E., Li, N. & Haeggstrom, J. Z., 2020, In: Journal of Thrombosis and Haemostasis. 18, 4, p. 976-984 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Integration of molecular profiles in a longitudinal wellness profiling cohort
Tebani, A., Gummesson, A., Zhong, W., Koistinen, I. S., Lakshmikanth, T., Olsson, L. M., Boulund, F., Neiman, M., Stenlund, H., Hellström, C., Karlsson, M. J., Arif, M., Dodig-Crnković, T., Mardinoglu, A., Lee, S., Zhang, C., Chen, Y., Olin, A., Mikes, J., Danielsson, H. & 18 others, , 2020, In: Nature Communications. 11, 1, 14 p., 4487.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Early life body size, growth and risks of systemic lupus erythematosus: A large Danish observational cohort study
Thomas, P. E., Jensen, B. W., Sørensen, K. K., Jacobsen, Søren, Aarestrup, J. & Baker, J. L., 2020, In: Seminars in Arthritis and Rheumatism. 50, 6, p. 1507-1512 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reduced carbohydrate and increased protein and fat in the diet augment the positive effect of weight loss on glucose control in type 2 diabetes patients
Thomsen, M. N., Skytte, M. J., Samkani, A., Carl, M. H., Weber, P., Astrup, A., Larsen, T. M., Frystyk, J., Holst, Jens Juul, Hartmann, Bolette, Thomsen, Henrik S., Chabanova, E., Madsbad, Sten, Haugaard, Steen Bendix & Krarup, T., 2020, In: Diabetologia. 63, Suppl. 1, p. S295-S296 614.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
The clinical effects of a carbohydrate-reduced high-protein diet on glycaemic variability in metformin-treated patients with type 2 diabetes mellitus: A randomised controlled study
Thomsen, M. N., fbg982, fbg982, Astrup, A., Deacon, Carolyn F., Holst, Jens Juul, Madsbad, Sten, Krarup, T., Haugaard, Steen Bendix & Samkani, A., 2020, In: Clinical Nutrition ESPEN. 39, p. 46-52 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Outcome of concomitant treatment with thiopurines and allopurinol in patients with inflammatory bowel disease: A nationwide Danish cohort study
Thomsen, S. B., Allin, K. H., Burisch, J., Jensen, C. B., Hansen, S., Gluud, Lise Lotte, Theede, K., Kiszka-Kanowitz, M., Nielsen, A. M. & Less, T., 2020, In: European Journal of Gastroenterology and Hepatology. 8, 1, p. 68-76Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic mapping of etiologic brain cell types for obesity
Timshel, P. N., Thompson, J. J. & Pers, Tune H, 2020, In: eLife. 9, 45 p., 55851.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Leptin Serum Levels are Associated With GLP-1 Receptor Agonist-Mediated Effects on Glucose Metabolism in Clozapine-or Olanzapine-Treated, Prediabetic, Schizophrenia Patients
Tomasik, J., Rustogi, N., Larsen, J. R., Jakobsen, M. I., Svensson, C. K., Vedtofte, L., Jakobsen, M. S. L., Jespersen, H. R., Koyuncu, K., Schjerning, O., Nielsen, Jimmi, Ekstrøm, Claus Thorn, Correll, C. U., Holst, Jens Juul, Vilsbøll, Tina, Bahn, S. & Fink-Jensen, Anders, 2020, In: Schizophrenia Bulletin Open. 1, 1, 11 p., sgaa044.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Metabolic insights from a GHSR-A203E mutant mouse model
Pedersen, Lola Julie Torz, Osborne-Lawrence, S., Rodriguez, J., He, Z., Paula Cornejo, M., Roman Mustafa, E., Jin, C., Petersen, N., Hedegaard, M. A., Nybo, Maja Lind, Martinez Damonte, V., Metzger, N. P., Mani, B. K., Williams, K. W., Raingo, J., Perello, M., Holst, Birgitte & Zigman, J. M., 2020, In: Molecular Metabolism. 39, 16 p., 101004.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Synthetic G protein-coupled bile acid receptor agonists and bile acids act via basolateral receptors in ileal and colonic mucosa
Tough, I. R., Schwartz, Thue W. & Cox, H. M., 2020, In: Neurogastroenterology and Motility. 32, 12, 14 p., e13943.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hepatic Bile Acid Reuptake in the Rat Depends on Bile Acid Conjugation but Not on Agonistic Properties towards FXR and TGR5
Trammell, Sam, Svenningsen, J. S., Holst, Jens Juul, Gillum, M. P. & Kuhre, Rune Ehrenreich, 2020, In: Molecules. 25, 14 p., 2371.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Describing the fecal metabolome in cryogenically collected samples from healthy participants
Trošt, K., Ahonen, L., Suvitaival, T., Christiansen, N., Nielsen, T., Thiele, M., Jacobsen, S., Krag, A., Rossing, Peter, Hansen, Torben, Dragsted, Lars Ove & Legido-Quigley, C., 2020, In: Scientific Reports. 10, 1, 8 p., 885.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Capturing Epidemics: Photographs by Howalt
Tybjerg, Karin, Scott-Fordsmand, Helene & Howalt, N., 2020Research output: Non-textual form › 2D/3D (psysical products) › Research
- Published
Et historisk perspektiv
Tybjerg, Karin, 2020, Personlig medicin : filosofiske og tværvidenskabelige perspektiver. Harnow Klausen, S. & Christiansen, K. (eds.). 1 ed. København: Munksgaard , p. 47-79 32 p. (Sundhed, menneske, samfund, Vol. 2).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Variation in Bile Microbiome by the Etiology of Cholestatic Liver Disease
Tyc, O., Jansen, C., Schierwagen, R., Uschner, F. E., Israelsen, M., Klein, S., Ortiz, C., Strassburg, C. P., Zeuzem, S., Gu, W., Torres, S., Praktiknjo, M., Kersting, S., Langheinrich, M., Nattermann, J., Servant, F., Arumugam, M., Krag, A., Lelouvier, B., Weismueller, T. J. & 1 others, , 2020, In: Liver Transplantation. 26, 12, p. 1652-1657 6 p.Research output: Contribution to journal › Letter › Research
- Published
One Year's Treatment with the Glucagon-Like Peptide 1 Receptor Agonist Liraglutide Decreases Hepatic Fat Content in Women with Nonalcoholic Fatty Liver Disease and Prior Gestational Diabetes Mellitus in a Randomized, Placebo-Controlled Trial
Vedtofte, L., Bahne, E., Foghsgaard, S., Bagger, J. I., Andreasen, C., Strandberg, C., Gortz, P. M., Holst, Jens Juul, Gronbaek, H., Svare, J. A., Clausen, Tine Dalsgaard, Mathiesen, Elisabeth, Damm, Peter, Gluud, Lise Lotte, Knop, Filip Krag & Vilsbøll, Tina, 2020, In: Journal of Clinical Medicine. 9, 10, 14 p., 3213.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucose-Dependent Insulinotropic Polypeptide Is a Pancreatic Polypeptide Secretagogue in Humans
Veedfald, Simon, Vedtofte, L., Skov-Jeppesen, Kirsa, Deacon, Carolyn F., Hartmann, Bolette, Vilsbøll, Tina, Knop, Filip Krag, Christensen, Mikkel Bring & Holst, Jens Juul, 2020, In: Journal of Clinical Endocrinology and Metabolism. 105, 3, p. e502-e510Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gut hormone secretion, gastric emptying and glucose absorption after frequently sampled oral glucose and liquid mixed meal tests in young men: [Meeting Abstract]
Veedfald, Simon, Rehfeld, Jens Frederik, vanHall, G., Svendsen, Lars Bo & Holst, Jens Juul, 2020, In: Neurogastroenterology and Motility. 32, SI, p. 56 1 p., 146.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Statin therapy is associated with lower prevalence of gut microbiota dysbiosis
Vieira-Silva, S., Falony, G., Belda, E., Nielsen, T., Aron-Wisnewsky, J., Chakaroun, R., Forslund, S. K., Assmann, K., Valles-Colomer, M., Nguyen, T. T. D., Proost, S., Prifti, E., Tremaroli, V., Pons, N., Le Chatelier, E., Andreelli, F., Bastard, J-P., Coelho, L. P., Galleron, N., Hansen, T. H. & 28 others, , 2020, In: Nature. 581, 7808, p. 310-315Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increase in adiposity from childhood to adulthood predicts a metabolically obese phenotype in normal-weight adults
Viitasalo, A., Pitkänen, N., Pahkala, K., Lehtimäki, T., Viikari, J. S. A., Raitakari, O. & Kilpeläinen, Tuomas O., 2020, In: International Journal of Obesity. 44, p. 848-851Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reply
Villumsen, M., Jess, T. & Allin, K. H., 2020, In: Clinical Gastroenterology and Hepatology. 18, 4, p. 1003-1004Research output: Contribution to journal › Comment/debate › Research
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Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
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Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets
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The isoenzyme pattern of LDH does not play a physiological role; except perhaps during fast transitions in energy metabolism
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