Novo Nordisk Foundation Center for Basic Metabolic Research

Metabolic effects of one-week binge drinking and fast food intake during Roskilde Festival in young healthy male adults

Demant, Mia Grønlund, Suppli, M. P., Foghsgaard, S., Gether, L., Grøndahl, M. F. G., Dalsgaard, N. B., Bergmann, S. S., Lanng, A. R., Gasbjerg, Lærke Smidt, Thomasen, M., Bagger, J. I., Strandberg, C., Kønig, M. J., Grønbæk, H., Becker, U., Holst, Jens Juul, Knop, J., Gillum, M. P., Vilsbøll, Tina & Knop, Filip Krag, Apr 2021, In: European Journal of Endocrinology. 185, 1, p. 23-32

Research output: Contribution to journal › Journal article › Research › peer-review

Deep muscle-proteomic analysis of freeze-dried human muscle biopsies reveals fiber type-specific adaptations to exercise training

Deshmukh, Atul Shahaji, Steenberg, D. E., Hostrup, Morten, Birk, Jesper Bratz, Larsen, Jeppe Kjærgaard, Santos, A., Kjøbsted, Rasmus, Hingst, J. R., Schéele, Camilla Charlotte Nielsen, Murgia, M., Kiens, Bente, Richter, Erik A., Mann, Matthias & Wojtaszewski, Jørgen F P, 2021, In: Nature Communications. 12, 15 p., 304.

Research output: Contribution to journal › Journal article › Research › peer-review

Genome-Wide Association Analysis of Pancreatic Beta-Cell Glucose Sensitivity

Deshmukh, H. A., Madsen, A. L., Viñuela, A., Have, C. T., Grarup, N., Tura, A., Mahajan, A., Heggie, A. J., Koivula, R. W., De Masi, F., Tsirigos, K. K., Linneberg, A., Drivsholm, T., Pedersen, O., Sørensen, T. I. A., Astrup, A., Gjesing, A. A. P., Pavo, I., Wood, A. R., Ruetten, H. & 14 others, Jones, A. G., Koopman, A. D. M., Cederberg, H., Rutters, F., Ridderstrale, M., Laakso, M., McCarthy, M. I., Frayling, T. M., Ferrannini, E., Franks, P. W., Pearson, E. R., Mari, A., Hansen, T. & Walker, M., 2021, In: Journal of Clinical Endocrinology and Metabolism. 106, 1, p. 80-90 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Risk of Urolithiasis in Patients With Inflammatory Bowel Disease: A Nationwide Danish Cohort Study 1977–2018

Dimke, H., Winther-Jensen, M., Allin, K. H., Lund, L. & Jess, T., 2021, In: Clinical Gastroenterology and Hepatology. 19, 12, p. 2532-2540.e2

Research output: Contribution to journal › Journal article › Research › peer-review

The role of the molecular circadian clock in human energy homeostasis

Dollet, L., Pendergrast, L. A. & Zierath, Juleen R, 2021, In: Current Opinion in Lipidology. 32, 1, p. 16-23 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Cell-free DNA and RNA - measurement and applications in clinical diagnostics with focus on metabolic disorders

Drag, Markus Hodal & Kilpeläinen, Tuomas O., 2021, In: Physiological Genomics. 53, 1, p. 33-46

Research output: Contribution to journal › Journal article › Research › peer-review

Glucagon-Like Peptide-1 Is Associated With Systemic Inflammation in Pediatric Patients Treated With Hematopoietic Stem Cell Transplantation

Sørum, Maria Ebbesen, Kissow, Hannelouise, Hartmann, Bolette, Kielsen, K., Sørensen, K., Stinson, Sara, Frithioff-Bojsoe, C., Fonvig, Cilius Esmann, Holm, Jens-Christian, Hansen, Torben, Holst, Jens Juul & Müller, K. G., 2021, In: Frontiers in Immunology. 12, 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The effects of a 2-year physical activity and dietary intervention on plasma lipid concentrations in children: the PANIC Study

Eloranta, A-M., Sallinen, T., Viitasalo, A., Lintu, N., Väistö, J., Jalkanen, H., Tompuri, T. T., Soininen, S., Haapala, E. A., Kiiskinen, S., Schnurr, T. M., Kilpeläinen, T. O., Mikkonen, S., Savonen, K., Atalay, M., Brage, S., Laaksonen, D. E., Lindi, V., Ågren, J., Schwab, U. & 2 others, Jääskeläinen, J. & Lakka, T. A., 2021, In: European Journal of Nutrition. 60, p. 425-434

Research output: Contribution to journal › Journal article › Research › peer-review

Estimation of SARS-CoV-2 Infection Fatality Rate by Real-time Antibody Screening of Blood Donors

Erikstrup, C., Hother, C. E., Pedersen, O. B. V., Mølbak, K., Skov, R. L., Holm, D. K., Saekmose, S. G., Nilsson, A. C., Brooks, P. T., Boldsen, J. K., Mikkelsen, C., Gybel-Brask, M., Sørensen, E., Dinh, K. M., Mikkelsen, S., Moller, B. K., Haunstrup, T., Harritshøj, L., Jensen, B. A., Hjalgrim, H. & 2 others, Lillevang, S. T. & Ullum, H., 2021, In: Clinical Infectious Diseases. 72, 2, p. 249-253 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Germline variants and breast cancer survival in patients with distant metastases at primary breast cancer diagnosis

Escala-Garcia, M., Canisius, S., Keeman, R., Beesley, J., Anton-Culver, H., Arndt, V., Augustinsson, A., Becher, H., Beckmann, M. W., Behrens, S., Bermisheva, M., Bojesen, S. E., Bolla, M. K., Brenner, H., Canzian, F., Castelao, J. E., Chang-Claude, J., Chanock, S. J., Couch, F. J., Czene, K. & 31 others, Daly, M. B., Dennis, J., Devilee, P., Dörk, T., Dunning, A. M., Easton, D. F., Ekici, A. B., Eliassen, A. H., Fasching, P. A., Flyger, H., Gago-Dominguez, M., García-Closas, M., García-Sáenz, J. A., Geisler, J., Giles, G. G., Grip, M., Gündert, M., Hahnen, E., Haiman, C. A., Håkansson, N., Hall, P., Hamann, U., Hartikainen, J. M., Heemskerk-Gerritsen, B. A. M., Hollestelle, A., Hoppe, R., Hopper, J. L., Luben, R. N., Scott, C., Wang, Q. & kConFab/AOCS Investigators, K. I., 2021, In: Scientific Reports. 11, 1, 11 p., 19787.

Research output: Contribution to journal › Journal article › Research › peer-review

Gut microbiota in human metabolic health and disease

Fan, Yong & Pedersen, Oluf Borbye, 2021, In: Nature Reviews. Microbiology. 19, p. 55-71 17 p.

Research output: Contribution to journal › Review › Research › peer-review

HIV infection drives interferon signaling within intestinal SARS-CoV-2 target cells

Fardoos, R., Asowata, O. E., Herbert, N., Nyquist, S. K., Zungu, Y., Singh, A., Ngoepe, A., Mbano, I. M., Mthabela, N., Ramjit, D., Karim, F., Kuhn, W., Madela, F. G., Manzini, V. T., Anderson, F., Berger, B., Pers, Tune H, Shalek, A. K., Leslie, A. & Kløverpris, Henrik Nyhus, 2021, In: JCI insight. 6, 16, e148920.

Research output: Contribution to journal › Journal article › Research › peer-review

Human skeletal muscle CD90⁺ fibro-adipogenic progenitors are associated with muscle degeneration in type 2 diabetic patients

Farup, J., Just, J., de Paoli, F., Lin, L., Jensen, J. B., Billeskov, T., Roman, I. S., Cömert, C., Møller, A. B., Madaro, L., Groppa, E., Fred, R. G., Kampmann, U., Gormsen, L. C., Pedersen, S. B., Bross, P., Stevnsner, T., Eldrup, N., Pers, T. H., Rossi, F. M. V. & 2 others, Puri, P. L. & Jessen, N., 2021, In: Cell Metabolism. 33, 11, p. 2201-2214.e11

Research output: Contribution to journal › Journal article › Research › peer-review

Editorial: Proglucagon-Derived Peptides

Flatt, P. R., Knop, Filip Krag & Tarasov, A. I., Nov 2021, In: Frontiers in Endocrinology. 12, 776871.

Research output: Contribution to journal › Editorial › Research

Human Milk Oligosaccharides Modulate Fecal Microbiota and Are Safe for Use in Children With Overweight: A Randomized Controlled Trial

Fonvig, Cilius Esmann, Amundsen, I. D., Vigsnæs, L. K., Sørensen, N., Frithioff-Bojsoe, C., Christiansen, M., Hedley, P. L., Holm, L. A., McConnell, B. & Holm, Jens-Christian, 2021, In: Journal of Pediatric Gastroenterology and Nutrition. 73, 3, p. 408-414 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Combinatorial, additive and dose-dependent drug–microbiome associations

Forslund, S. K., Chakaroun, R., Zimmermann-Kogadeeva, M., Markó, L., Aron-Wisnewsky, J., Nielsen, T., Moitinho-Silva, L., Schmidt, T. S. B., Falony, G., Vieira-Silva, S., Adriouch, S., Alves, R. J., Assmann, K., Bastard, J. P., Birkner, T., Caesar, R., Chilloux, J., Coelho, L. P., Fezeu, L., Galleron, N. & 23 others, Helft, G., Isnard, R., Ji, B., Kuhn, M., Le Chatelier, E., Myridakis, A., Olsson, L., Pons, N., Prifti, E., Quinquis, B., Roume, H., Lewinter, C., Søndertoft, N. B., Pedersen, H. K., Hansen, T. H., Hartmann, Bolette, Holst, Jens Juul, Hornbak, M., Jørgensen, Niklas Rye, Justesen, Johanne Marie, Krarup, N., Svendstrup, M. & The MetaCardis Consortium*, T. M. C., 2021, In: Nature. 600, p. 500-517 18 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Maximal fat oxidation rate is higher in fit women and unfit women with obesity, compared to normal weight unfit women

Frandsen, J., Hansen, I. M. D., Wismann, J. F., Olsen, M. H., Brage-Andersen, M. R., Sahl, Ronni Eg, Hansen, M., Ingersen, Arthur, Modvig, J. L., Schmücker, M., brl298, brl298, Dela, Flemming, Larsen, Steen & Helge, Jørn Wulff, 2021, In: Journal of Clinical Endocrinology and Metabolism. 106, 11, p. E4389-E4399 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Effects of whey protein and dietary fiber intake on insulin sensitivity, body composition, energy expenditure, blood pressure, and appetite in subjects with abdominal obesity

Fuglsang-Nielsen, R., Rakvaag, E., Langdahl, B., Knudsen, K. E. B., Hartmann, Bolette, Holst, Jens Juul, Hermansen, K. & Gregersen, S., 2021, In: European Journal of Clinical Nutrition. 75, p. 611–619

Research output: Contribution to journal › Journal article › Research › peer-review

Disrupted circadian oscillations in type 2 diabetes are linked to altered rhythmic mitochondrial metabolism in skeletal muscle

Gabriel, B. M., Altıntaş, Ali, Smith, J. A. B., Sardon-Puig, L., Zhang, X., Basse, A. L., Laker, R. C., Gao, H., Liu, Z., Dollet, L., Treebak, Jonas Thue, Zorzano, A., Huo, Z., Rydén, M., Lanner, J. T., Esser, K. A., Barrès, Romain, Pillon, N. J., Krook, A. & Zierath, Juleen R, 2021, In: Science Advances. 7, 43, 20 p., eabi9654.

Research output: Contribution to journal › Journal article › Research › peer-review

Genome-wide association study identifies novel susceptibility loci for KIT D816V positive mastocytosis

Galatà, G., García-Montero, A. C., Kristensen, T., Dawoud, A. A. Z., Muñoz-González, J. I., Meggendorfer, M., Guglielmelli, P., Hoade, Y., Alvarez-Twose, I., Gieger, C., Strauch, K., Ferrucci, L., Tanaka, T., Bandinelli, S., Schnurr, T. M., Haferlach, T., Broesby-Olsen, S., Vestergaard, H., Møller, M. B., Bindslev-Jensen, C. & 7 others, Vannucchi, A. M., Orfao, A., Radia, D., Reiter, A., Chase, A. J., Cross, N. C. P. & Tapper, W. J., 2021, In: American Journal of Human Genetics. 108, 2, p. 284-294 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The liver–alpha cell axis associates with liver fat and insulin resistance: a validation study in women with non-steatotic liver fat levels

Gar, C., Haschka, S. J., Kern-Matschilles, S., Rauch, B., Sacco, V., Prehn, C., Adamski, J., Seissler, J., Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul & Lechner, A., 2021, In: Diabetologia. 64, 3, p. 512-520

Research output: Contribution to journal › Journal article › Research › peer-review

Dose-dependent efficacy of the glucose-dependent insulinotropic polypeptide (GIP)receptor antagonistGIP(3-30)NH₂ on GIP actions in humans

Gasbjerg, Lærke Smidt, Bari, E. J., Stensen, S., Hoe, B., Lanng, A. R., Mathiesen, D. S., Christensen, Mikkel Bring, Hartmann, Bolette, Holst, Jens Juul, Rosenkilde, Mette & Knop, Filip Krag, 2021, In: Diabetes, Obesity and Metabolism. 23, 1, p. 68-74

Research output: Contribution to journal › Journal article › Research › peer-review

Exendin(9-39)NH2: Recommendations for clinical use based on a systematic literature review

Gasbjerg, Lærke Smidt, Bari, E. J., Christensen, Mikkel Bring & Knop, Filip Krag, 2021, In: Diabetes, Obesity and Metabolism. 23, 11, p. 2419-2436

Research output: Contribution to journal › Journal article › Research › peer-review

Expression of Cholecystokinin and its Receptors in the Intestinal Tract of Type 2 Diabetes Patients and Healthy Controls

Gilliam-Vigh, H., Jorsal, T., Rehfeld, Jens Frederik, Pedersen, Jens, Poulsen, Steen Seier, Vilsbøll, Tina & Knop, Filip Krag, 2021, In: Journal of Clinical Endocrinology and Metabolism. 106, 8, p. 2164-2170 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Ecological adaptation and succession of human fecal microbial communities in an automated in vitro fermentation system

Gnanasekaran, Thiyagarajan, Geraldo, Juliana Assis, Ahrenkiel, D. W., Alvarez Silva, Maria Camila, Saenz, C., Khan, Adnan, Hanteer, O., Gunalan, V., Trost, K., Moritz, Thomas & Arumugam, Mani, 2021, In: mSystems. 6, 4, 18 p., e00232-21.

Research output: Contribution to journal › Journal article › Research › peer-review

Discovery of thymosin β4 as a human exerkine and growth factor

Gonzalez-Franquesa, A., Stocks, Ben Nicholas, Borg, M. L., Kuefner, M., Kellezi, Emilie Dalbram, Nielsen, Thomas Svava, Agrawal, A., Pankratova, Stanislava, Chibalin, A. V., Karlsson, H. K. R., Gheibi, S., Björnholm, M., Jørgensen, Niklas Rye, Clemmensen, Christoffer, Treebak, Jonas Thue, Hostrup, Morten, Krook, A., Zierath, Juleen R & Deshmukh, Atul Shahaji, 2021, In: American Journal of Physiology: Cell Physiology. 321, 5, p. C770-C778 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Insulin and 5-aminoimidazole-4-carboxamide ribonucleotide (Aicar) differentially regulate the skeletal muscle cell secretome

Gonzalez-Franquesa, A., Peijs, Lone, Cervone, D. T., Koçana, C., Zierath, Juleen R & Deshmukh, Atul Shahaji, 2021, In: Proteomes. 9, 3, 16 p., 37.

Research output: Contribution to journal › Journal article › Research › peer-review

Mass-spectrometry-based proteomics reveals mitochondrial supercomplexome plasticity

Gonzalez-Franquesa, A., Stocks, Ben Nicholas, Chubanava, Sabina, Hattel, H. B., Moreno Justicia, Roger, Peijs, Lone, Treebak, Jonas Thue, Zierath, Juleen R & Deshmukh, Atul Shahaji, 2021, In: Cell Reports. 35, 8, 20 p., 109180.

Research output: Contribution to journal › Journal article › Research › peer-review

Determinants of penetrance and variable expressivity in monogenic metabolic conditions across 77,184 exomes

Goodrich, J. K., Singer-Berk, M., Son, R., Sveden, A., Wood, J., England, E., Cole, J. B., Weisburd, B., Watts, N., Caulkins, L., Dornbos, P., Koesterer, R., Zappala, Z., Zhang, H., Maloney, K. A., Dahl, A., Aguilar-Salinas, C. A., Atzmon, G., Barajas-Olmos, F., Barzilai, N. & 31 others, Blangero, J., Boerwinkle, E., Bonnycastle, L. L., Bottinger, E., Bowden, D. W., Centeno-Cruz, F., Chambers, J. C., Chami, N., Chan, E., Chan, J., Cheng, C. Y., Cho, Y. S., Contreras-Cubas, C., Córdova, E., Correa, A., DeFronzo, R. A., Duggirala, R., Dupuis, J., Garay-Sevilla, M. E., García-Ortiz, H., Gieger, C., Glaser, B., González-Villalpando, C., Gonzalez, M. E., Grarup, N., Groop, L., Gross, M., Hansen, Torben, Linneberg, Allan René, Pedersen, Oluf Borbye & AMP-T2D-GENES Consortia, A. C., 2021, In: Nature Communications. 12, 15 p., 3505.

Research output: Contribution to journal › Journal article › Research › peer-review

The power of genetic diversity in genome-wide association studies of lipids

Graham, S. E., Clarke, S. L., Wu, K-H. H., Kanoni, S., Zajac, G. J. M., Ramdas, S., Surakka, I., Ntalla, I., Vedantam, S., Winkler, T. W., Locke, A. E., Marouli, E., Hwang, M. Y., Han, S., Narita, A., Choudhury, A., Bentley, A. R., Ekoru, K., Verma, A., Trivedi, B. & 504 others, Martin, H. C., Hunt, K. A., Hui, Q., Klarin, D., Zhu, X., Thorleifsson, G., Helgadottir, A., Gudbjartsson, D. F., Holm, H., Olafsson, I., Akiyama, M., Sakaue, S., Terao, C., Kanai, M., Zhou, W., Brumpton, B. M., Rasheed, H., Ruotsalainen, S. E., Havulinna, A. S., Veturi, Y., Feng, Q., Rosenthal, E. A., Lingren, T., Pacheco, J. A., Pendergrass, S. A., Haessler, J., Giulianini, F., Bradford, Y., Miller, J. E., Campbell, A., Lin, K., Millwood, I. Y., Hindy, G., Rasheed, A., Faul, J. D., Zhao, W., Weir, D. R., Turman, C., Huang, H., Graff, M., Mahajan, A., Brown, M. R., Zhang, W., Yu, K., Schmidt, E. M., Pandit, A., Gustafsson, S., Yin, X., Luan, J., Zhao, J., Matsuda, F., Jang, H., Yoon, K., Medina-Gomez, C., Pitsillides, A., Hottenga, J. J., Willemsen, G., Wood, A. R., Ji, Y., Gao, Z., Haworth, S., Mitchell, R. E., Chai, J. F., Aadahl, Mette, Yao, J., Manichaikul, A., Warren, H. R., Ramirez, J., Bork-Jensen, J., Karhus, L. L., Goel, A., Sabater-Lleal, M., Noordam, R., Sidore, C., Fiorillo, E., McDaid, A. F., Marques-Vidal, P., Wielscher, M., Trompet, S., Sattar, N., Møllehave, Line Tang, Thuesen, B. H., Munz, M., Zeng, L., Huang, J., Yang, B., Poveda, A., Kurbasic, A., Lamina, C., Forer, L., Scholz, M., Galesloot, T. E., Bradfield, J. P., Daw, E. W., Zmuda, J. M., Mitchell, J. S., Fuchsberger, C., Christensen, H., Brody, J. A., Feitosa, M. F., Wojczynski, M. K., Preuss, M., Mangino, M., Christofidou, P., Verweij, N., Benjamins, J. W., Engmann, J., Kember, R. L., Slieker, R. C., Lo, K. S., Zilhao, N. R., Phuong Le, Kleber, M. E., Delgado, G. E., Huo, S., Ikeda, D. D., Iha, H., Yang, J., Liu, J., Leonard, H. L., Marten, J., Schmidt, B., Arendt, M., Smyth, L. J., Canadas-Garre, M., Wang, C., Nakatochi, M., Wong, A., Hutri-Kahonen, N., Sim, X., Xia, R., Huerta-Chagoya, A., Fernandez-Lopez, J. C., Lyssenko, V., Ahmed, M., Jackson, A. U., Irvin, M. R., Oldmeadow, C., Kim, H., Ryu, S., Timmers, P. R. H. J., Arbeeva, L., Dorajoo, R., Lange, L. A., Chai, X., Prasad, G., Lores-Motta, L., Pauper, M., Long, J., Li, X., Theusch, E., Takeuchi, F., Spracklen, C. N., Loukola, A., Bollepalli, S., Warner, S. C., Wang, Y. X., Wei, W. B., Nutile, T., Ruggiero, D., Sung, Y. J., Hung, Y., Chen, S., Liu, F., Yang, J., Kentistou, K. A., Gorski, M., Brumat, M., Meidtner, K., Bielak, L. F., Smith, J. A., Hebbar, P., Farmaki, A., Hofer, E., Lin, M., Xue, C., Zhang, J., Concas, M. P., Vaccargiu, S., van der Most, P. J., Pitkanen, N., Cade, B. E., Lee, J., van Der Laan, S. W., Chitrala, K. N., Weiss, S., Zimmermann, M. E., Lee, J. Y., Choi, H. S., Nethander, M., Freitag-Wolf, S., Southam, L., Rayner, N. W., Wang, C. A., Lin, S., Wang, J., Couture, C., Lyytikainen, L., Nikus, K., Cuellar-Partida, G., Vestergaard, H., Hildalgo, B., Giannakopoulou, O., Cai, Q., Obura, M. O., van Setten, J., Li, X., Schwander, K., Terzikhan, N., Shin, J. H., Jackson, R. D., Reiner, A. P., Martin, L. W., Chen, Z., Li, L., Highland, H. M., Young, K. L., Kawaguchi, T., Thiery, J., Bis, J. C., Nadkarni, G. N., Launer, L. J., Li, H., Nalls, M. A., Raitakari, O. T., Ichihara, S., Wild, S. H., Nelson, C. P., Campbell, H., Jager, S., Nabika, T., Al-Mulla, F., Niinikoski, H., Braund, P. S., Kolcic, I., Kovacs, P., Giardoglou, T., Katsuya, T., Bhatti, F., de Kleijn, D., de Borst, G. J., Kim, E. K., Adams, H. H. H., Ikram, M. A., Zhu, X., Asselbergs, F. W., Kraaijeveld, A. O., Beulens, J. W. J., Shu, X., Rallidis, L. S., Pedersen, Oluf Borbye, Hansen, Torben, Mitchell, P., Hewitt, A. W., Kahonen, M., Perusse, L., Bouchard, C., Tonjes, A., Chen, Y. I., Pennell, C. E., Mori, T. A., Lieb, W., Franke, A., Ohlsson, C., Mellstrom, D., Cho, Y. S., Lee, H., Yuan, J., Koh, W., Rhee, S. Y., Woo, J., Heid, I. M., Stark, K. J., Volzke, H., Homuth, G., Evans, M. K., Zonderman, A. B., Polasek, O., Pasterkamp, G., Hoefer, I. E., Redline, S., Pahkala, K., Oldehinkel, A. J., Snieder, H., Biino, G., Schmidt, R., Schmidt, H., Chen, Y. E., Bandinelli, S., Dedoussis, G., Thanaraj, T. A., Kardia, S. L. R., Kato, N., Schulze, M. B., Girotto, G., Jung, B., Boger, C. A., Joshi, P. K., Bennett, D. A., De Jager, P. L., Lu, X., Mamakou, V., Brown, M., Caulfield, M. J., Munroe, P. B., Guo, X., Ciullo, M., Jonas, J. B., Samani, N. J., Kaprio, J., Pajukanta, P., Adair, L. S., Bechayda, S. A., de Silva, H. J., Wickremasinghe, A. R., Krauss, R. M., Wu, J., Zheng, W., den Hollander, A. I., Bharadwaj, D., Correa, A., Wilson, J. G., Lind, L., Heng, C., Nelson, A. E., Golightly, Y. M., Wilson, J. F., Penninx, B., Kim, H., Attia, J., Scott, R. J., Rao, D. C., Arnett, D. K., Walker, M., Koistinen, H. A., Chandak, G. R., Yajnik, C. S., Mercader, J. M., Tusie-Luna, T., Aguilar-Salinas, C. A., Villalpando, C. G., Orozco, L., Fornage, M., Tai, E. S., van Dam, R. M., Lehtimaki, T., Chaturvedi, N., Yokota, M., Liu, J., Reilly, D. F., McKnight, A. J., Kee, F., Jockel, K., McCarthy, M. I., Palmer, C. N. A., Vitart, V., Hayward, C., Simonsick, E., van Duijn, C. M., Lu, F., Qu, J., Hishigaki, H., Lin, X., Marz, W., Parra, E. J., Cruz, M., Gudnason, V., Tardif, J., Lettre, G., 't Hart, L. M., Elders, P. J. M., Damrauer, S. M., Kumari, M., Kivimaki, M., van der Harst, P., Spector, T. D., Loos, R. J. F., Province, M. A., Psaty, B. M., Brandslund, I., Pramstaller, P. P., Christensen, K., Ripatti, S., Widen, E., Hakonarson, H., Grant, S. F. A., Kiemeney, L. A. L. M., de Graaf, J., Loeffler, M., Kronenberg, F., Gu, D., Erdmann, J., Schunkert, H., Franks, P. W., Linneberg, Allan René, Jukema, J. W., Khera, A. 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D., Jousilahti, P., Salomaa, V., Hveem, K., Asvold, B. O., Kubo, M., Kamatani, Y., Okada, Y., Murakami, Y., Thorsteinsdottir, U., Stefansson, K., Ho, Y., Lynch, J. A., Rader, D. J., Tsao, P. S., Chang, K., Cho, K., O'Donnell, C. J., Gaziano, J. M., Wilson, P., Rotimi, C. N., Hazelhurst, S., Ramsay, M., Trembath, R. C., van Heel, D. A., Tamiya, G., Yamamoto, M., Kim, B., Mohlke, K. L., Frayling, T. M., Hirschhorn, J. N., Kathiresan, S., Boehnke, M., Natarajan, P., Peloso, G. M., Brown, C. D., Morris, A. P., Assimes, T. L., Deloukas, P., Sun, Y. V. & Willer, C. J., 2021, In: Nature. 600, p. 675-679

Research output: Contribution to journal › Journal article › Research › peer-review

An abundant biliary fatty acid metabolite derived from dietary omega-3 polyunsaturated fatty acids regulates triglycerides

Grevengoed, Trisha Jean, Trammell, Sam, Svenningsen, J. S., Makarov, M., Nielsen, Thomas Svava, Jacobsen, Jens Christian Brings, Calder, P. C., Migaud, M. E., Cravatt, B. & Gillum, M. P., 2021, In: Journal of Clinical Investigation. 131, 6, 12 p., e143861.

Research output: Contribution to journal › Journal article › Research › peer-review

Treatment of type 2 diabetes in children: what are the specific considerations?

Grondahl, M. F. G., Johannesen, Jesper, Kristensen, K. & Knop, Filip Krag, 2021, In: Expert Opinion on Pharmacotherapy. 22, 16, p. 2127-2141 15 p.

Research output: Contribution to journal › Journal article › Research › peer-review

MultiPep: a hierarchical deep learning approach for multi-label classification of peptide bioactivities

Grønning, Alexander GB, Kacprowski, T. & Schéele, Camilla Charlotte Nielsen, 2021, In: Biology Methods and Protocols. 6, 1, 16 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Selective release of gastrointestinal hormones induced by an orally active GPR39 agonist

Grunddal, K. V., Diep, T. A., Petersen, N., Tough, I. R., Skov, Louise Julie, Liu, L., Buijink, J. A., Mende, F., Jin, C., Jepsen, Sara Lind, Sørensen, L. M. E., Achiam, Michael Patrick, Strandby, R. B., Bach, Anders, Hartmann, Bolette, Frimurer, Thomas Michael, Hjorth, Siv Annegrethe, Bouvier, M., Cox, H. & Holst, Birgitte, 2021, In: Molecular Metabolism. 49, 14 p., 101207.

Research output: Contribution to journal › Journal article › Research › peer-review

Enabling single-cell trajectory network enrichment

Grønning, Alexander GB, Oubounyt, M., Kanev, K., Lund, J., Kacprowski, T., Zehn, D., Röttger, R. & Baumbach, J., 2021, In: Nature Computational Science. 1, 2, p. 153-163

Research output: Contribution to journal › Journal article › Research › peer-review

The Living Room: En gentænkning af museumsgenstandes endeligt

Grünfeld, Martin, 2021, In: Danske Museer. 34

Research output: Contribution to journal › Journal article › Communication

Can Metabolite and Hormone Profiles Provide a Rationale for Choosing Between Bariatric Procedures?

Guimarães, M., Pereira, S. S., Holst, Jens Juul, Nora, M. & Monteiro, M. P., 2021, In: Obesity Surgery. 31, p. 2174-2179

Research output: Contribution to journal › Journal article › Research › peer-review

Longitudinal plasma protein profiling of newly diagnosed type 2 diabetes

Gummesson, A., Björnson, E., Fagerberg, L., Zhong, W., Tebani, A., Edfors, F., Schmidt, C., Lundqvist, A., Adiels, M., Bäckhed, F., Schwenk, J. M., Jansson, P. A., Uhlén, M. & Bergström, G., 2021, In: EBioMedicine. 63, 11 p., 103147.

Research output: Contribution to journal › Journal article › Research › peer-review

Identification and Metabolic Profiling of a Novel Human Gut-derived LEAP2 Fragment

Hagemann, C. A., Zhang, C., Hansen, H. H., Jorsal, T., Rigbolt, K. T. G., Madsen, M. R., Bergmann, N. C., Heimbürger, S. M. N., Falkenhahn, M., Theis, S., Breitschopf, K., Holm, Stephanie Kjærulff, Hedegaard, M. A., Christensen, Mikkel Bring, Vilsbøll, Tina, Holst, Birgitte, Vrang, N., Jelsing, J. & Knop, Filip Krag, 2021, In: The Journal of clinical endocrinology and metabolism. 106, 2, p. e966-e981

Research output: Contribution to journal › Journal article › Research › peer-review

Leaky Gut as a Potential Culprit for the Paradoxical Dysglycemic Response to Gastric Bypass-Associated Ileal Microbiota

Hankir, M. K., Seyfried, F., Schellinger, I. N., Schlegel, N. & Arora, Tulika, 2021, In: Metabolites. 11, 3, 10 p., 153.

Research output: Contribution to journal › Journal article › Research › peer-review

The Biochemical Pathways of Nicotinamide-Derived Pyridones

Hayat, F., Sonavane, M., Makarov, M. V., Trammell, Sam, McPherson, P., Gassman, N. R. & Migaud, M. E., 2021, In: International Journal of Molecular Sciences. 22, 3, 28 p., 1145.

Research output: Contribution to journal › Journal article › Research › peer-review

Maternal obesity and metabolic disorders associate with congenital heart defects in the offspring: A systematic review

Hedermann, G., Hedley, P. L., Thagaard, I. N., Krebs, Lone, Ekelund, Charlotte Kvist, Sørensen, Thorkild I.A. & Christiansen, M., May 2021, In: PLoS ONE. 16, 5 , 22 p., e0252343.

Research output: Contribution to journal › Review › Research › peer-review

Six-day sc GIP infusion increases plasma NEFA without altering the adipose tissue transcriptome, GIPR levels or plasma markers of inflammation in patients with type 1 diabetes

Heimburger, S. M. N., Hoe, B., Nielsen, C. N., Hartmann, Bolette, Holst, Jens Juul, Dela, Flemming, Overgaard, J., Størling, Joachim, Vilsbøll, Tina, Dejgaard, T. F., Pyke, C., Christensen, M. B. & Knop, Filip Krag, 2021, In: Diabetologia. 64, SUPPL 1, p. 258-258 494.

Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

The effect of 6-day subcutaneous glucose-dependent insulinotropic polypeptide infusion on time in glycaemic range in patients with type 1 diabetes: a randomised, double-blind, placebo-controlled crossover trial

Heimbürger, S. M. N., Hoe, B., Nielsen, C. N., Bergmann, N. C., Hartmann, Bolette, Holst, Jens Juul, Vilsbøll, Tina, Dejgaard, T. F., Christensen, Mikkel Bring & Knop, Filip Krag, 2021, In: Diabetologia. 64, p. 2425-2431

Research output: Contribution to journal › Journal article › Research › peer-review

The gut microbiota regulates hypothalamic inflammation and leptin sensitivity in Western diet-fed mice via a GLP-1R-dependent mechanism

Heiss, C. N., Mannerås-Holm, L., Lee, Y. S., Serrano-Lobo, J., Håkansson Gladh, A., Seeley, R. J., Drucker, D. J., Bäckhed, F. & Olofsson, L. E., 2021, In: Cell Reports. 35, 8, 16 p., 109163.

Research output: Contribution to journal › Journal article › Research › peer-review

Brown Adipose Tissue: A Metabolic Regulator in a Hypothalamic Cross Talk?

Henningsen, J. B. & Schéele, Camilla Charlotte Nielsen, 2021, In: Annual Review of Physiology. 83, p. 279-301 23 p.

Research output: Contribution to journal › Review › Research › peer-review

Effects of excitotoxicity in the hypothalamus in transgenic mouse models of Huntington disease

Henningsen, J. B., Soylu-Kucharz, R., Bjorkqvist, M. & Petersen, Å., 2021, In: Heliyon. 7, 8, 9 p., 07808.

Research output: Contribution to journal › Journal article › Research › peer-review

Explaining deep neural networks for knowledge discovery in electrocardiogram analysis

Hicks, S. A., Isaksen, Jonas L., Thambawita, V., Ghouse, Jonas, Ahlberg, Gustav, Linneberg, Allan René, Grarup, N., Strümke, I., Ellervik, Christina, Olesen, Morten Steen Salling, Hansen, Torben, Graff, C., von Holstein-Rathlou, Niels-Henrik, Halvorsen, P., Maleckar, M. M., Riegler, M. A. & Kanters, Jørgen K., 2021, In: Scientific Reports. 11, 1, 11 p., 10949.

Research output: Contribution to journal › Journal article › Research › peer-review

The role of GLP-1 in postprandial glucose metabolism after bariatric surgery: a narrative review of human GLP-1 receptor antagonist studies

Hindsø, M., Svane, M. S., Hedbäck, N., Holst, Jens Juul, Madsbad, Sten & Bojsen-Møller, K. N., 2021, In: Surgery for Obesity and Related Diseases. 17, 7, p. 1383-1391

Research output: Contribution to journal › Review › Research › peer-review

Microbial regulation of hexokinase 2 links mitochondrial metabolism and cell death in colitis

Hinrichsen, F., Hamm, J., Westermann, M., Schröder, L., Shima, K., Mishra, N., Walker, A., Sommer, N., Klischies, K., Prasse, D., Zimmermann, J., Kaiser, S., Bordoni, D., Fazio, A., Marinos, G., Laue, G., Imm, S., Tremaroli, V., Basic, M., Häsler, R. & 10 others, Schmitz, R. A., Krautwald, S., Wolf, A., Stecher, B., Schmitt-Kopplin, P., Kaleta, C., Rupp, J., Bäckhed, F., Rosenstiel, P. & Sommer, F., 2021, In: Cell Metabolism. 33, 12, p. 2355-2366.e8

Research output: Contribution to journal › Journal article › Research › peer-review

What is Diabetes Remission?

Holst, Jens Juul & Madsbad, Sten, 2021, In: Diabetes Therapy. 12, p. 641-646 6 p.

Research output: Contribution to journal › Comment/debate › Research › peer-review

The role of incretins on insulin function and glucose homeostasis

Holst, Jens Juul, Gasbjerg, Lærke Smidt & Rosenkilde, Mette, 2021, In: Endocrinology. 162, 7, 10 p., bqab065.

Research output: Contribution to journal › Review › Research › peer-review

Treatment of Type 2 Diabetes and Obesity on the Basis of the Incretin System: The 2021 Banting Medal for Scientific Achievement Award Lecture

Holst, Jens Juul, 2021, In: Diabetes. 70, 11, p. 2468-2475 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

What combines best with GLP-1 for obesity treatment: GIP receptor agonists or antagonists?

Holst, Jens Juul, 2021, In: Cell Reports Medicine. 2, 5, 2 p., 100284.

Research output: Contribution to journal › Comment/debate › Research

Genome-wide discovery of genetic loci that uncouple excess adiposity from its comorbidities

Huang, L. O., Rauch, A., Mazzaferro, E., Preuss, M., Carobbio, S., Bayrak, C. S., Chami, N., Wang, Z., Schick, U. M., Yang, N., Itan, Y., Vidal-Puig, A., den Hoed, M., Mandrup, S., Kilpeläinen, Tuomas O. & Loos, R. J. F., 2021, In: Nature Metabolism. 3, 2, p. 228-243 16 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Do genetic risk scores for childhood adiposity operate independent of BMI of their mothers?

Huang, L. O., Morgen, C. S., Ängquist, Lars, Nohr, E. A., Kilpeläinen, Tuomas O., Hansen, Torben, Sørensen, Thorkild I.A. & Schnurr, T. M., 2021, In: International Journal of Obesity. 45, 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Hypothalamic hormone-sensitive lipase regulates appetite and energy homeostasis

Johnsen, Cecilie Hundahl, Kotzbeck, P., Burm, Hayley Beth, Christiansen, S. H., Pedersen, Lola Julie Torz, zmw799, zmw799, Madsen, M. P., Ratner, C., Serup, A. K., Thompson, J. J., Eichmann, T. O., Pers, Tune H, Woldbye, David Paul Drucker, Piomelli, D., Kiens, Bente, Zechner, R., Skov, Louise Julie & Holst, Birgitte, 2021, In: Molecular Metabolism. 47, 16 p., 101174.

Research output: Contribution to journal › Journal article › Research › peer-review

Dietary Fiber Is Essential to Maintain Intestinal Size, L-Cell Secretion, and Intestinal Integrity in Mice

Dal, Jenna Elizabeth Hunt, Hartmann, Bolette, Schoonjans, K., Holst, Jens Juul & Kissow, Hannelouise, 2021, In: Frontiers in Endocrinology. 12, 10 p., 640602.

Research output: Contribution to journal › Journal article › Research › peer-review

GLP-1 and Intestinal Diseases

Dal, Jenna Elizabeth Hunt, Holst, Jens Juul, Jeppesen, Palle Bekker & Kissow, Hannelouise, 2021, In: Biomedicines. 9, 4, 14 p., 383.

Research output: Contribution to journal › Review › Research › peer-review

Intestinal Growth in Glucagon Receptor Knockout Mice Is Not Associated With the Formation of AOM/DSS-Induced Tumors

Dal, Jenna Elizabeth Hunt, Yassin, M., Olsen, Jørgen, Hartmann, Bolette, Holst, Jens Juul & Kissow, Hannelouise, 2021, In: Frontiers in Endocrinology. 12, 7 p., 695145.

Research output: Contribution to journal › Journal article › Research › peer-review

"Visceral Consciousness": The Gut-Brain Axis in Victorian Sleep and Sleeplessness in Britain and America, 1850-1914

Hussey, Kristin D., 2021, In: Bulletin of the History of Medicine. 95, 3, p. 350-378

Research output: Contribution to journal › Journal article › Research › peer-review

Book Review: Exploring Emotion, Care, and Enthusiasm in “Unloved” Museum Collections. eds. Anna Woodham, Alison Hess, and Rhianedd Smith

Hussey, Kristin D., 2021, In: Museums Worlds: Advances in Research. 9, p. 222-223 2 p.

Research output: Contribution to journal › Literature review › Research

Clinical images, imperial power and Bhau Daji’s secret treatment for leprosy at the Royal College of Physicians Museum

Hussey, Kristin D. & Biggins, M., 2021, In: Science Museum Group Journal. Spring 2021, 15

Research output: Contribution to journal › Journal article › Research › peer-review

Replacing Red Meat with Other Nonmeat Food Sources of Protein is Associated with a Reduced Risk of Type 2 Diabetes in a Danish Cohort of Middle-Aged Adults

Ibsen, D. B., Jakobsen, M. U., Halkjær, J., Tjønneland, Anne, Kilpeläinen, Tuomas O., Parner, E. T. & Overvad, K., 2021, In: The Journal of Nutrition. 151, 5, p. 1241-1248 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Changes in intake of dairy product subgroups and risk of type 2 diabetes: modelling specified food substitutions in the Danish Diet, Cancer and Health cohort

Ibsen, D. B., Overvad, K., Laursen, A. S. D., Halkjær, J., Tjønneland, Anne, Kilpeläinen, Tuomas O., Parner, E. T. & Jakobsen, M. U., 2021, In: European Journal of Nutrition. 60, p. 3449–3459 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Molecular mechanism of ligand binding pathways and activation of the succinate receptor

Iliyaz, Aslihan Shenol, Lückmann, Michael, Trauelsen, Mette, Frimurer, Thomas Michael & Schwartz, Thue W., 2021, In: European Biophysics Journal. 50, Suppl. 1, p. 160 1 p., P-234.

Research output: Contribution to journal › Conference abstract in journal › Research

Comprehensive lipidomics reveals phenotypic differences in hepatic lipid turnover in ALD and NAFLD during alcohol intoxication

Israelsen, M., Kim, M., Suvitaival, T., Madsen, B. S., Hansen, C. D., Torp, N., Trost, K., Thiele, M., Hansen, Torben, Legido-Quigley, C., Krag, A. & MicrobLiver Consortium, M. C., 2021, In: JHEP Reports. 3, 5, 11 p., 100325.

Research output: Contribution to journal › Journal article › Research › peer-review

Lysates of Methylococcus capsulatus Bath induce a lean-like microbiota, intestinal FoxP3⁺RORγt⁺IL-17⁺ Tregs and improve metabolism

Jensen, B. A. H., Holm, J. B., Larsen, I. S., von Burg, N., Derer, S., Sonne, S. B., Pærregaard, S. I., Damgaard, M. V., Indrelid, S. A., Rivollier, A., Agrinier, A. L., Sulek, K., Arnoldussen, Y. J., Fjære, E., Marette, A., Angell, I. L., Rudi, K., Treebak, J. T., Madsen, L., Åkesson, C. P. & 5 others, Agace, W., Sina, C., Kleiveland, C. R., Kristiansen, Karsten & Lea, T. E., 2021, In: Nature Communications. 12, 19 p., 1093.

Research output: Contribution to journal › Journal article › Research › peer-review

Isolation and characterization of muscle stem cells, fibro-adipogenic progenitors, and macrophages from human skeletal muscle biopsies

Jensen, J. B., Møller, A. B., Just, J., Mose, M., de Paoli, F. V., Billeskov, T. B., Fred, Rikard Göran, Pers, Tune H, Pedersen, S. B., Petersen, K. K., Bjerre, M., Farup, J. & Jessen, N., 2021, In: American Journal of Physiology - Cell Physiology. 321, 2, p. C257-C268 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The effect of dietary carbohydrate restriction beyond weight loss on health-related quality of life and cognition

Jensen, N. J., Wodschow, H. Z., fbg982, fbg982, Samkani, A., Astrup, A., Frystyk, J., Hartmann, Bolette, Holst, Jens Juul, Larsen, T. M., Madsbad, Sten, Magkos, Faidon, Miskowiak, Kamilla, Rungby, Jørgen, Haugaard, Steen Bendix & Thomsen, M. N., 2021, In: Diabetologia. 64, SUPPL 1, p. 62-63 114.

Research output: Contribution to journal › Conference abstract in journal › Research

Antagonizing somatostatin receptor subtype 2 and 5 reduces blood glucose in a gut- and GLP-1R-dependent manner

Jepsen, Sara Lind, Albrechtsen, Nicolai Jacob Wewer, Windeløv, Johanne Agerlin, Galsgaard, Katrine Douglas, Dal, Jenna Elizabeth Hunt, Farb, T. B., Kissow, Hannelouise, Pedersen, J., Deacon, Carolyn F., Martin, R. E. & Holst, Jens Juul, 2021, In: JCI insight. 6, 4, 15 p., e143228.

Research output: Contribution to journal › Journal article › Research › peer-review

Amyotrophic lateral sclerosis in the Faroe Islands - a genealogical study

Johansen, M., Svenstrup, K., Mortensen, O., Andorsdottir, G., Steig, B. A., Joensen, P., Hansen, Torben & Petersen, M. S., 2021, In: Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration. 22, 7-8, p. 571-575 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

r-cubed: Guiding the overwhelmed scientist from random wrangling to Reproducible Research in R

Johnston, L., Juel, H., Lengger, B., Witte, D., Chatwin, H., Christiansen, Malene Revsbech & Isaksen, A., 2021, In: Journal of Open Source Education. 4, 44, 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Genome-wide association study of circulating levels of glucagon during an oral glucose tolerance test

Jonsson, Anna Elisabet, Stinson, Sara, Torekov, Signe Sørensen, Clausen, Tine Dalsgaard, Færch, K., Kelstrup, Louise, Grarup, N., Mathiesen, Elisabeth, Damm, Peter, Witte, D. R., Jørgensen, M. E., Pedersen, Oluf Borbye, Holst, Jens Juul & Hansen, Torben, 2021, In: BMC Medical Genomics. 14, 7 p., 3.

Research output: Contribution to journal › Journal article › Research › peer-review

Effects of Manipulating Circulating Bile Acid Concentrations on Postprandial GLP-1 Secretion and Glucose Metabolism After Roux-en-Y Gastric Bypass

Jonsson, I., Bojsen-Moller, K. N., Kristiansen, V. B., Veedfald, Simon, Albrechtsen, Nicolai Jacob Wewer, Clausen, T. R., Kuhre, Rune Ehrenreich, Rehfeld, Jens Frederik, Holst, Jens Juul, Madsbad, Sten & Svane, M. S., 2021, In: Frontiers in Endocrinology. 12, 11 p., 681116.

Research output: Contribution to journal › Journal article › Research › peer-review

The C-terminal peptide of CCL21 drastically augments CCL21 activity through the dendritic cell lymph node homing receptor CCR7 by interaction with the receptor N-terminus

Jørgensen, Astrid Sissel, Brandum, E. P., Mikkelsen, J. M., Orfin, K. A., Boilesen, D. R., Egerod, Kristoffer Lihme, Moussouras, N. A., Vilhardt, Frederik, Kalinski, P., Basse, P., Chen, Yen-Hsi, Yang, Zhang, Dwinell, M. B., Volkman, B. F., Veldkamp, C. T., Holst, Peter Johannes, Lahl, K., Goth, C. K., Rosenkilde, Mette & Hjortø, Gertrud Malene, 2021, In: Cellular and Molecular Life Sciences. 78, p. 6963-6978 16 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Glucose-Dependent Insulinotropic Peptide in the High-Normal Range Is Associated With Increased Carotid Intima-Media Thickness

Jujic, A., Nilsson, P. M., Atabaki-Pasdar, N., Dieden, A., Tuomi, T., Franks, P. W., Holst, Jens Juul, Torekov, Signe Sørensen, Ravassa, S., Diez, J., Persson, M., Ahlqvist, E., Melander, O., Gomez, M. F., Groop, L. & Magnusson, M., 2021, In: Diabetes Care. 44, 1, p. 224-230 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Acute metabolic effects of melatonin - A randomized crossover study in healthy young men

Kampmann, U., Lauritzen, E. S., Grarup, N., Jessen, N., Hansen, Torben, Møller, N. & Stoy, J., 2021, In: Journal of Pineal Research. 70, 2, 13 p., 12706.

Research output: Contribution to journal › Journal article › Research › peer-review

Gastric Residual to Predict Necrotizing Enterocolitis in Preterm Piglets As Models for Infants

Kappel, S. S., Sangild, Per Torp, Hilsted, Linda, Hartmann, Bolette, Thymann, Thomas & Aunsholt, Lise, 2021, In: Journal of Parenteral and Enteral Nutrition. 45, 1, p. 87-93

Research output: Contribution to journal › Journal article › Research › peer-review

Genomic diversity and ecology of human-associated Akkermansia species in the gut microbiome revealed by extensive metagenomic assembly

Karcher, N., Nigro, E., Puncochar, M., Blanco-Miguez, A., Ciciani, M., Manghi, P., Zolfo, M., Cumbo, F., Manara, S., Golzato, D., Cereseto, A., Arumugam, Mani, Bui, T. P. N., Tytgat, H. L. P., Valles-Colomer, M., de Vos, W. M. & Segata, N., 2021, In: Genome Biology. 22, 24 p., 209.

Research output: Contribution to journal › Journal article › Research › peer-review

Quantitative phosphoproteomic analysis of IRS1 in skeletal muscle from men with normal glucose tolerance or type 2 diabetes: A case-control study

Karlsson, H. K. R., Kasahara, A., Ikeda, M., Chibalin, A. V., Harada, J., Rydén, M., Krook, A., Kato, M., Kubota, K. & Zierath, Juleen R, 2021, In: Metabolism. 118, 7 p., 154726.

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Arginine-vasopressin mediates counter-regulatory glucagon release and is diminished in type 1 diabetes

Kim, A., Knudsen, J. G., Madara, J. C., Benrick, A., Hill, T. G., Kadir, L. A., Kellard, J. A., Mellander, L., Miranda, C., Lin, H., James, T., Suba, K., Spigelman, A. F., Wu, Y., Macdonald, P. E., Asterholm, I. W., Magnussen, T., Christensen, M., Vilsbøll, T., Salem, V. & 4 others, Knop, Filip Krag, Rorsman, P., Lowell, B. B. & Briant, L. J. B., 2021, In: eLife. 10, 29 p., e72919.

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Editorial: non-selective beta blockers—in and out of circulation

Kimer, N., Mortensen, C. & Hobolth, L., Mar 2021, In: Alimentary Pharmacology and Therapeutics. 53, 5, p. 632-633 2 p.

Research output: Contribution to journal › Editorial › Research › peer-review

Revision rates of trapeziometacarpal total joint arthroplasty in relation to occupational hand force requirements

Kirkeby, L., Frost, Poul, Svendsen, S. W. & Hansen, Torben, 2021, In: Journal of Hand Surgery: European Volume. 46, 9, p. 968-974 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Loss of Function Glucose-Dependent Insulinotropic Polypeptide Receptor Variants Are Associated With Alterations in BMI, Bone Strength and Cardiovascular Outcomes

Kizilkaya, Hüsün Sheyma, Sørensen, Kimmie Vestergaard, Kibsgaard, C. J., Gasbjerg, Lærke Smidt, Hauser, Alexander Sebastian, wbf943, wbf943, Grarup, N. & Rosenkilde, Mette, 2021, In: Frontiers in Cell and Developmental Biology. 9, 12 p., 749607.

Research output: Contribution to journal › Journal article › Research › peer-review

Neprilysin Inhibition Increases Glucagon Levels in Humans and Mice With Potential Effects on Amino Acid Metabolism

Kjeldsen, Sasha Alexandra Sampson, Hansen, L. H., Esser, N., Mongovin, S., Winther-Sørensen, Marie, Galsgaard, Katrine Douglas, Dal, Jenna Elizabeth Hunt, Kissow, Hannelouise, Ceutz, F. R., Terzic, D., Mark, P. D., Plomgaard, Peter Stendahl, Goetze, Jens P. , Goossens, G. H., Blaak, E. E., Deacon, Carolyn F., Rosenkilde, Mette, Zraika, S., Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2021, In: Endocrine Research. 5, 9, 15 p., bvab084.

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Discovery of GPR183 Agonists Based on an Antagonist Scaffold

Kjær, Viktoria Madeline Skovgaard, Ieremias, L., Daugvilaite, V., Lückmann, Michael, Frimurer, Thomas Michael, Ulven, Trond, Rosenkilde, Mette & Våbenø, J., 2021, In: ChemMedChem. 16, 17, p. 2623-2627

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Pharmacological but not physiological GDF15 suppresses feeding and the motivation to exercise

Klein, A. B., Nicolaisen, T. S., Ørtenblad, N., Gejl, K. D., Jensen, R., Fritzen, A. M., Larsen, E. L., Karstoft, K., Poulsen, H. E., Morville, T., Sahl, R. E., Helge, J. W., Lund, J., Falk, S., Lyngbæk, M., Ellingsgaard, H., Pedersen, B. K., Lu, W., Finan, B., Jørgensen, S. B. & 5 others, Seeley, R. J., Kleinert, Maximilian, Kiens, Bente, Richter, Erik A. & Clemmensen, Christoffer, 2021, In: Nature Communications. 12, 9 p., 1041.

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Curbing gastrointestinal infections by defensin fragment modifications without harming commensal microbiota

Koeninger, L., Osbelt, L., Berscheid, A., Wendler, J., Berger, J., Hipp, K., Lesker, T. R., Pils, M. C., Malek, N. P., Jensen, Benjamin Anderschou Holbech, Brötz-Oesterhelt, H., Strowig, T. & Jan Wehkamp, W., 2021, In: Communications Biology . 4, 1, 11 p., 47.

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Effect of fecal microbiota transplantation combined with Mediterranean diet on insulin sensitivity in subjects with metabolic syndrome

Koopen, A. M., Almeida, E. L., Attaye, I., Witjes, J. J., Rampanelli, E., Majait, S., Kemper, M., Levels, J. H. M., Schimmel, A. W. M., Herrema, H., Scheithauer, T. P. M., Frei, W., Dragsted, Lars Ove, Hartmann, Bolette, Holst, Jens Juul, O’Toole, P. W., Groen, A. K. & Nieuwdorp, M., 2021, In: Frontiers in Microbiology. 12, 15 p., 662159.

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A-769662 inhibits adipocyte glucose uptake in an AMPK-independent manner

Kopietz, F., Alshuweishi, Y., Bijland, S., Alghamdi, F., Degerman, E., Sakamoto, Kei, Salt, I. P. & Göransson, O., 2021, In: Biochemical Journal. 478, 3, p. 633-646 14 p.

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Gut microbial metabolites as multi-kingdom intermediates

Krautkramer, K. A., Fan, J. & Backhed, F., 2021, In: Nature Reviews. Microbiology. 19, p. 77-94 18 p.

Research output: Contribution to journal › Review › Research › peer-review

Novel Anti-inflammatory Treatments in Cirrhosis. A Literature-Based Study

Kronborg, T. M., Lambert, Henriette Ytting, Hobolth, L., Møller, Søren & Kimer, N., 2021, In: Frontiers in Medicine. 8, 718896.

Research output: Contribution to journal › Review › Research › peer-review

Do sodium-glucose transporter-2 inhibitors increase plasma glucagon by direct actions on the alpha-cell? - and does the increase matter for the associated increase in endogenous glucose production?

Kuhre, Rune Ehrenreich, Deacon, Carolyn F., Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, 2021, In: Diabetes, Obesity and Metabolism. 23, 9, p. 2009-2019

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L-Cell Expression of Melanocortin-4-Receptor Is Marginal in Most of the Small Intestine in Mice and Humans and Direct Stimulation of Small Intestinal Melanocortin-4-Receptors in Mice and Rats Does Not Affect GLP-1 Secretion

Kuhre, Rune Ehrenreich, Modvig, Ida Marie, Jepsen, Sara Lind, Kizilkaya, Hüsün Sheyma, Bæch-Laursen, C., Smith, C. A., Reimann, F., Gribble, F. M., Rosenkilde, Mette & Holst, Jens Juul, 2021, In: Frontiers in Endocrinology. 12, 12 p., 690387.

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What Is an L-Cell and How Do We Study the Secretory Mechanisms of the L-Cell?

Kuhre, Rune Ehrenreich, Deacon, Carolyn F., Holst, Jens Juul & Petersen, N., 2021, In: Frontiers in Endocrinology. 12, 19 p., 694284.

Research output: Contribution to journal › Review › Research › peer-review

Large-scale association analyses identify host factors influencing human gut microbiome composition

Kurilshikov, A., Medina-Gomez, C., Bacigalupe, R., Radjabzadeh, D., Wang, J., Demirkan, A., Le Roy, C. I., Raygoza Garay, J. A., Finnicum, C. T., Liu, X., Zhernakova, D. V., Bonder, M. J., Hansen, T. H., Frost, F., Rühlemann, M. C., Turpin, W., Moon, J. Y., Kim, H. N., Lüll, K., Barkan, E. & 84 others, Shah, S. A., Fornage, M., Szopinska-Tokov, J., Wallen, Z. D., Borisevich, D., Agreus, L., Andreasson, A., Bang, C., Bedrani, L., Bell, J. T., Bisgaard, H., Boehnke, M., Boomsma, D. I., Burk, R. D., Claringbould, A., Croitoru, K., Davies, G. E., van Duijn, C. M., Duijts, L., Falony, G., Fu, J., van der Graaf, A., Hansen, Torben, Homuth, G., Hughes, D. A., Ijzerman, R. G., Jackson, M. A., Jaddoe, V. W. V., Joossens, M., Jørgensen, T., Keszthelyi, D., Knight, R., Laakso, M., Laudes, M., Launer, L. J., Lieb, W., Lusis, A. J., Masclee, A. A. M., Moll, H. A., Mujagic, Z., Qibin, Q., Rothschild, D., Shin, H., Sørensen, Søren Johannes, Steves, C. J., Thorsen, Jonathan Jan Ilve, Timpson, N. J., Tito, R. Y., Vieira-Silva, S., Völker, U., Völzke, H., Võsa, U., Wade, K. H., Walter, S., Watanabe, K., Weiss, S., Weiss, F. U., Weissbrod, O., Westra, H. J., Willemsen, G., Payami, H., Jonkers, D. M. A. E., Arias Vasquez, A., de Geus, E. J. C., Meyer, K. A., Stokholm, Jakob, Segal, E., Org, E., Wijmenga, C., Kim, H. L., Kaplan, R. C., Spector, T. D., Uitterlinden, A. G., Rivadeneira, F., Franke, A., Lerch, M. M., Franke, L., Sanna, S., D’Amato, M., Pedersen, Oluf Borbye, Paterson, A. D., Kraaij, R., Raes, J. & Zhernakova, A., 2021, In: Nature Genetics. 53, p. 156-165 19 p.

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Protocol for a randomised, double-blinded, placebo-controlled, double-dummy 6-week clinical trial comparing the treatment effects of the glucagon-like peptide 1 receptor agonist liraglutide versus the bile acid sequestrant colesevelam on bile acid malabsorption

Kårhus, M. L., Brønden, A., Forman, Julie Lyng, Haaber, A., Vilsbøll, Tina, Sonne, D. P. & Knop, Filip Krag, 2021, In: BMJ Open. 11, 2, e044711.

Research output: Contribution to journal › Comment/debate › Research › peer-review