Novo Nordisk Foundation Center for Basic Metabolic Research

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  1. 2023
  2. Published

    Incretin-based therapy of metabolic disease

    Holst, Jens Juul, 2023, In: Danish Medical Journal. 70, 1, A10220597.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Machine learning models for blood pressure phenotypes combining multiple polygenic risk scores

    Hrytsenko, Y., Shea, B., Elgart, M., Kurniansyah, N., Lyons, G., Morrison, A. C., Carson, A. P., Haring, B., Mitchel, B. D., Psaty, B. M., Jaeger, B. C., Gu, C. C., Kooperberg, C., Levy, D., Lloyd-Jones, D., Choi, E., Brody, J. A., Smith, J. A., Rotter, J. I., Moll, M. & 18 others, Fornage, M., Simon, N., Castaldi, P., Casanova, R., Chung, R., Kaplan, R., Loos, Ruth, Kardia, S. L. R., Rich, S. S., Redline, S., Kelly, T., O'Connor, T., Zhao, W., Kim, W., Guo, X., Chen, Y. D. I., Sofer, T. & Trans-Omics in Precision Medicine Consortium, T. I. P. M. C., 2023, medRxiv, 41 p.

    Research output: Working paper › Preprint › Research

  4. Published

    An adult-based genetic risk score for liver fat associates with liver and plasma lipid traits in children and adolescents

    Huang, Yun, Stinson, Sara, Juel, H. B., Lund, M. A. V., Holm, Louise Aas, Fonvig, Cilius Esmann, Nielsen, T., Grarup, Niels, Pedersen, Oluf Borbye, Christiansen, M., Chabanova, E., Thomsen, Henrik S., Krag, A., Stender, S., Holm, Jens-Christian & Hansen, Torben, 2023, In: Liver International. 43, 8, p. 1772-1782 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    The power of TOPMed imputation for the discovery of Latino-enriched rare variants associated with type 2 diabetes

    Huerta-Chagoya, A., Schroeder, P., Mandla, R., Deutsch, A. J., Zhu, W., Petty, L., Yi, X., Cole, J. B., Udler, M. S., Dornbos, P., Porneala, B., DiCorpo, D., Liu, C. T., Li, J. H., Szczerbiński, L., Kaur, V., Kim, J., Lu, Y., Martin, A., Eizirik, D. L. & 31 others, Marchetti, P., Marselli, L., Chen, L., Srinivasan, S., Todd, J., Flannick, J., Gubitosi-Klug, R., Levitsky, L., Shah, R., Kelsey, M., Burke, B., Dabelea, D. M., Divers, J., Marcovina, S., Stalbow, L., Loos, Ruth, Darst, B. F., Kooperberg, C., Raffield, L. M., Haiman, C., Sun, Q., McCormick, J. B., Fisher-Hoch, S. P., Ordoñez, M. L., Meigs, J., Baier, L. J., González-Villalpando, C., González-Villalpando, M. E., Orozco, L., García-García, L. & Mexican Biobank, M. B., 2023, In: Diabetologia. 66, p. 1273-1288 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Timeless spaces: Field experiments in the physiological study of circadian rhythms, 1938–1963

    Hussey, Kristin D., 2023, In: History and Philosophy of the Life Sciences. 45, 25 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    PFAS Exposures and the Human Metabolome: A Systematic Review of Epidemiological Studies

    India-Aldana, S., Yao, M., Midya, V., Colicino, E., Chatzi, L., Chu, J., Gennings, C., Jones, D. P., Loos, Ruth, Setiawan, V. W., Smith, M. R., Walker, R. W., Barupal, D., Walker, D. I. & Valvi, D., 2023, In: Current Pollution Reports. 9, p. 510-568

    Research output: Contribution to journal › Review › Research › peer-review

  8. Published

    Effects of aerobic training and semaglutide treatment on pancreatic β-cell secretory function in patients with type 2 diabetes

    Ingersen, Arthur, Schmücker, Malte, Alexandersen, C., Graungaard, B., Thorngreen, T., Borch, Jacob, Holst, Jens Juul, Helge, Jørn Wulff & Dela, Flemming, 2023, In: Journal of Clinical Endocrinology and Metabolism. 108, 11, p. 2798–2811

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Rifaximin-α for liver fibrosis in patients with alcohol-related liver disease (GALA-RIF): a randomised, double-blind, placebo-controlled, phase 2 trial

    Israelsen, M., Madsen, B. S., Torp, N., Johansen, S., Hansen, C. D., Detlefsen, S., Andersen, P., Hansen, J. K., Lindvig, K. P., Rasmussen, D. N., Thorhauge, K. H., Kjærgaard, M., Karsdal, M., Hansen, Torben, Arumugam, Mani, Trebicka, J., Thiele, M., Krag, A. & GALAXY, G., 2023, In: The Lancet Gastroenterology and Hepatology. 8, 6, p. 523-532 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Methylome and proteome integration in human skeletal muscle uncover group and individual responses to high-intensity interval training

    Jacques, M., Landen, S., Romero, J. A., Hiam, D., Schittenhelm, R. B., Hanchapola, I., Shah, A. D., Voisin, S. & Eynon, N., 2023, In: FASEB Journal. 37, 10, 18 p., e23184.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Mosaic chromosomal alterations in blood across ancestries using whole-genome sequencing

    Jakubek, Y. A., Zhou, Y., Stilp, A., Bacon, J., Wong, J. W., Ozcan, Z., Arnett, D., Barnes, K., Bis, J. C., Boerwinkle, E., Brody, J. A., Carson, A. P., Chasman, D. I., Chen, J., Cho, M., Conomos, M. P., Cox, N., Doyle, M. F., Fornage, M., Guo, X. & 31 others, Kardia, S. L. R., Lewis, J. P., Loos, Ruth, Ma, X., Machiela, M. J., Mack, T. M., Mathias, R. A., Mitchell, B. D., Mychaleckyj, J. C., North, K., Pankratz, N., Peyser, P. A., Preuss, M. H., Psaty, B., Raffield, L. M., Vasan, R. S., Redline, S., Rich, S. S., Rotter, J. I., Silverman, E. K., Smith, J. A., Smith, A. P., Taub, M., Taylor, K. D., Yun, J., Li, Y., Desai, P., Bick, A. G., Reiner, A. P., Scheet, P. & Auer, P. L., 2023, In: Nature Genetics. 55, 11, p. 1912-1919 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Weight loss maintenance with exercise and liraglutide improves glucose tolerance, glucagon response, and beta cell function

    Jensen, Simon Birk Kjær, Juhl, C. R., Janus, C., Lundgren, J. R., Martinussen, C., Wiingaard, C., Knudsen, C., Frikke-Schmidt, Ruth, Stallknecht, Bente Merete, Holst, Jens Juul, Madsbad, Sten & Torekov, Signe Sørensen, 2023, In: Obesity. 31, 4, p. 977-989 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Precision medicine in complex diseases - Molecular subgrouping for improved prediction and treatment stratification

    Johansson, Å., Andreassen, O. A., Brunak, Søren, Franks, P. W., Hedman, H., Loos, Ruth, Meder, B., Melén, E., Wheelock, C. E. & Jacobsson, B., 2023, In: Journal of Internal Medicine. 294, 4, p. 378-396 19 p.

    Research output: Contribution to journal › Review › Research › peer-review

  14. Published

    Mitochondrial phosphatidylethanolamine modulates UCP1 to promote brown adipose thermogenesis

    Johnson, J. M., Peterlin, A. D., Balderas, E., Sustarsic, E. G., Maschek, J. A., Lang, M. J., Jara-Ramos, A., Panic, V., Morgan, J. T., Villanueva, C. J., Sanchez, A., Rutter, J., Lodhi, I. J., Cox, J. E., Fisher-Wellman, K. H., Chaudhuri, D., Gerhart-Hines, Zach & Funai, K., 2023, In: Science Advances. 9, 8, 15 p., eade7864.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Endogenous incretin levels and risk of first incident cancer: a prospective cohort study

    Jujic, A., Godina, C., Belting, M., Melander, O., Holst, Jens Juul, Ahlqvist, E., Gomez, M. F., Nilsson, P. M., Jernstrom, H. & Magnusson, M., 2023, In: Scientific Reports. 13, 1, 11 p., 382.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Glucose metabolism, gut-brain hormones, and acromegaly treatment: an explorative single centre descriptive analysis

    Jørgensen, N. T., Erichsen, T. M., Jørgensen, M. B., Idorn, T., Feldt-Rasmussen, Bo, Holst, Jens Juul, Feldt-Rasmussen, Ulla & Klose, M., 2023, In: Pituitary. 26, p. 152–163

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Analysis of DNA methylation at birth and in childhood reveals changes associated with season of birth and latitude

    Kadalayil, L., Alam, M. Z., White, C. H., Ghantous, A., Walton, E., Gruzieva, O., Merid, S. K., Kumar, A., Roy, R. P., Solomon, O., Huen, K., Eskenazi, B., Rzehak, P., Grote, V., Langhendries, J. P., Verduci, E., Ferre, N., Gruszfeld, D., Gao, L., Guan, W. & 83 others, Zeng, X., Schisterman, E. F., Dou, J. F., Bakulski, K. M., Feinberg, J. I., Soomro, M. H., Pesce, G., Baiz, N., Isaevska, E., Plusquin, M., Vafeiadi, M., Roumeliotaki, T., Langie, S. A. S., Standaert, A., Allard, C., Perron, P., Bouchard, L., van Meel, E. R., Felix, J. F., Jaddoe, V. W. V., Yousefi, P. D., Ramlau-Hansen, C. H., Relton, C. L., Tobi, E. W., Starling, A. P., Yang, I. V., Llambrich, M., Santorelli, G., Lepeule, J., Salas, L. A., Bustamante, M., Ewart, S. L., Zhang, H., Karmaus, W., Röder, S., Zenclussen, A. C., Jin, J., Nystad, W., Page, C. M., Magnus, M., Jima, D. D., Hoyo, C., Maguire, R. L., Kvist, T., Czamara, D., Räikkönen, K., Gong, T., Ullemar, V., Rifas-Shiman, S. L., Oken, E., Almqvist, C., Karlsson, R., Lahti, J., Murphy, S. K., Håberg, S. E., London, S., Herberth, G., Arshad, H., Sunyer, J., Grazuleviciene, R., Dabelea, D., Steegers-Theunissen, R. P. M., Nohr, E. A., Sørensen, Thorkild I.A., Duijts, L., Hivert, M. F., Nelen, V., Popovic, M., Kogevinas, M., Nawrot, T. S., Herceg, Z., Annesi-Maesano, I., Fallin, M. D., Yeung, E., Breton, C. V., Koletzko, B., Holland, N., Wiemels, J. L., Melén, E., Sharp, G. C., Silver, M. J., Rezwan, F. I. & Holloway, J. W., 2023, In: Clinical Epigenetics. 15, 23 p., 148.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    A second update on mapping the human genetic architecture of COVID-19

    Kanai, M., Andrews, S., Cordioli, M., Stevens, C., Neale, B. M., Daly, M., Ganna, A., Pathak, G. A., Ellinghaus, D., Banasik, K., Brunak, S., Pedersen, O. B., Westergaard, D., Sequeros, C. B., Nissen, J., Feldt-Rasmussen, U., Grønbæk, K., Ostrowski, S. R., Guindo-Martinez, M., Garcia, S. M. & 70 others, Hjalgrim, Henrik, Admin team lead, A. T. L., Admin team member, A. T. M., Analysis team lead, A. T. L., Analysis team member, A. T. M., Data collection lead, D. C. L., Data collection member, D. C. M., Manuscript analysis team lead, M. A. T. L., Manuscript analysis team members: Mendelian randomization, M. A. T. M. M. R., Manuscript analysis team members: methods development, M. A. T. M. M. D., Manuscript analysis team members: phenome-wide association study, M. A. T. M. P. A. S., Manuscript analysis team members: principal component projection, gene prioritization, M. A. T. M. P. C. P. G. P., Project management lead, P. M. L., Scientific communication lead, S. C. L., Scientific communication member, S. C. M., Writing group lead, W. G. L., Writing group member, W. G. M., 23andMe, 2., Adolescent brain and cognitive development study, A. B. A. C. D. S., Analysis group, A. G., Armenia_Covid-19hg, A., Assessment of the influence of clinical, functional, immunological and genetic factors on the severity of the course of coronavirus infection with SARS-CoV-2 and post-COVID syndrome, A. O. T. I. O. C. F. I. A. G. F. O. T. S. O. T. C. O. C. I. W. S. A. P. S., Avon Longitudinal Study of Parents and Children (ALSPAC), A. L. S. O. P. A. C. (., BelCovid, B., Biobanque Quebec COVID19, B. Q. C., BioVU, B., Bonn Study of COVID-19 Genetics, B. S. O. C. G., CGEn HostSeq—Canadian COVID-19 Human Host Genome Sequencing Databank, C. H. C. H. H. G. S. D., Colorado Center for Personalized Medicine—CCPM, C. C. F. P. M., COMRI/Virology Study, C. S., Covid19 Ioannina Biobank, C. I. B., COVID19-Host(a)ge, C., Covid19hg-CL, C., Danish COVID-19 Genomic Consortium, D. C. G. C., Egypt hgCOVID hub, E. H. H., EraCORE, E., FinnGen, F., French hgCOVID, F. H., GCAT. Genomes For Life, G. G. F. L., Genes & Health, G. &. H., Genetic influences on severity of COVID-19 illness in Korea, G. I. O. S. O. C. I. I. K., GenOMICC, G., Genotek COVID-19 study, G. C. S., Helix Exome+ COVID-19 Phenotypes, H. E. C. P., Host Genetic Factors for COVID-19 Severity and Outcome in Western Indian Population, H. G. F. F. C. S. A. O. I. W. I. P., Host Genetics in COVID Cohorts of Mixed ancestry from Mexico, H. G. I. C. C. O. M. A. F. M., Japan Coronavirus Taskforce, J. C. T., Japan NCGM-COVID19, J. N., Jordan COVID-19 Host Genomics Initiative (JCHGI), J. C. H. G. I. (., Leadership, L., Lung eQTL Consortium, L. E. C., Mass General Brigham—Host Vulnerability to COVID-19, M. G. B. V. T. C., MexGen-COVID, M., Pa-COVID-19, P., Project management group, P. M. G., Project management support, P. M. S., Qatar Genome Program, Q. G. P., SARS-CoV-2 and Host Genome sequencing, S. A. H. G. S., Scientific communication group, S. C. G., Search for Genomic Markers Predicting the Severity of the response to COVID-19, S. F. G. M. P. T. S. O. T. R. T. C., Spanish COalition to Unlock Research on host GEnetics on COVID-19 (SCOURGE), S. C. T. U. R. O. H. G. O. C. (., The Danish Blood Donor Study, T. D. B. D. S., The Genetic Predisposition to severe COVID-19, T. G. P. T. S. C., Tirschenreuth Study (TiKoco), T. S. (., UCLA Precision Health COVID-19 Host Genomics Biobank, U. P. H. C. H. G. B., UK Biobank, U. B., Variability in Immune Response Genes and Severity of SARS-CoV-2 Infection (INMUNGEN-CoV2 study), V. I. I. R. G. A. S. O. S. I. (. S., Website development, W. D., Writing Group, W. G. & The COVID-19 Host Genetics Initiative, T. C. H. G. I., 2023, In: Nature. 621, 7977, p. E7-E26 23 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  19. Published

    Dietary medium-chain fatty acids reduce food intake via the GDF15-GFRAL axis in mice

    Kanta, Josephine Maria, Deisen, L., Johann, K., Holm, Stephanie Kjærulff, Lundsgaard, Anne-Marie, Lund, Jens, Jähnert, M., Schürmann, A., Clemmensen, Christoffer, Kiens, Bente, Fritzen, Andreas Mæchel & Kleinert, Maximilian, 2023, In: Molecular Metabolism. 74, 10 p., 101760.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Gut bacterial metabolism contributes to host global purine homeostasis

    Kasahara, K., Kerby, R. L., Zhang, Q., Pradhan, M., Mehrabian, M., Lusis, A. J., Bergström, G., Bäckhed, F. & Rey, F. E., 2023, In: Cell Host and Microbe. 31, 6, p. 1038-1053.e10

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Maturity-onset diabetes of the young og graviditet

    Kauffmann, A., Jørgensen, I. L., Thuesen, Anne Cathrine Baun, Ringholm, Lene, Clausen, Tine Dalsgaard, Mathiesen, Elisabeth, Hansen, Torben & Damm, Peter, 2023, In: Ugeskrift for Laeger. 185, 21, V02230067.

    Research output: Contribution to journal › Review › Research › peer-review

  22. Published

    Arrest of movement induced by Pedunculopontine-stimulation obstructs hippocampal theta rhythm

    Kaur, Jaspreet, Komi, Salif Axel, Dmytriyeva, O., Houser, Grace Anne, Bonfils, M. C. A. & Berg, Rune W., 2023, bioRxiv, p. 1-14, 14 p.

    Research output: Working paper › Preprint › Research

  23. Published

    Questioning the fetal microbiome illustrates pitfalls of low-biomass microbial studies

    Kennedy, K. M., de Goffau, M. C., Perez-Muñoz, M. E., Arrieta, M. C., Bäckhed, F., Bork, P., Braun, T., Bushman, F. D., Dore, J., de Vos, W. M., Earl, A. M., Eisen, J. A., Elovitz, M. A., Ganal-Vonarburg, S. C., Gänzle, M. G., Garrett, W. S., Hall, L. J., Hornef, M. W., Huttenhower, C., Konnikova, L. & 26 others, Lebeer, S., Macpherson, A. J., Massey, R. C., McHardy, A. C., Koren, O., Lawley, T. D., Ley, R. E., O’Mahony, L., O’Toole, P. W., Pamer, E. G., Parkhill, J., Raes, J., Rattei, T., Salonen, A., Segal, E., Segata, N., Shanahan, F., Sloboda, D. M., Smith, G. C. S., Sokol, H., Spector, T. D., Surette, M. G., Tannock, G. W., Walker, A. W., Yassour, M. & Walter, J., 2023, In: Nature. 613, 7945, p. 639-649 11 p.

    Research output: Contribution to journal › Review › Research › peer-review

  24. Published

    Synergy and oxygen adaptation for development of next-generation probiotics

    Khan, M. T., Dwibedi, C., Sundh, D., Pradhan, M., Kraft, J. D., Caesar, R., Tremaroli, V., Lorentzon, M. & Bäckhed, F., 2023, In: Nature. 620, p. 381-385

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Chronotype, Unhealthy Lifestyle, and Diabetes Risk in Middle-Aged U.S. Women: A Prospective Cohort Study

    Kianersi, S., Liu, Y., Guasch Ferre, Marta, Redline, S., Schernhammer, E., Sun, Q. & Huang, T., 2023, In: Annals of Internal Medicine. 176, 10, p. 1330-1339 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Genome-wide association analyses define pathogenic signaling pathways and prioritize drug targets for IgA nephropathy

    Kiryluk, K., Sanchez-Rodriguez, E., Zhou, X. J., Zanoni, F., Liu, L., Mladkova, N., Khan, A., Marasa, M., Zhang, J. Y., Balderes, O., Sanna-Cherchi, S., Bomback, A. S., Canetta, P. A., Appel, G. B., Radhakrishnan, J., Trimarchi, H., Sprangers, B., Cattran, D. C., Reich, H., Pei, Y. & 168 others, Ravani, P., Galesic, K., Maixnerova, D., Tesar, V., Stengel, B., Metzger, M., Canaud, G., Maillard, N., Berthoux, F., Berthelot, L., Pillebout, E., Monteiro, R., Nelson, R., Wyatt, R. J., Smoyer, W., Mahan, J., Samhar, A. A., Hidalgo, G., Quiroga, A., Weng, P., Sreedharan, R., Selewski, D., Davis, K., Kallash, M., Vasylyeva, T. L., Rheault, M., Chishti, A., Ranch, D., Wenderfer, S. E., Samsonov, D., Claes, D. J., Akchurin, O., Goumenos, D., Stangou, M., Nagy, J., Kovacs, T., Fiaccadori, E., Amoroso, A., Barlassina, C., Cusi, D., Del Vecchio, L., Battaglia, G. G., Bodria, M., Boer, E., Bono, L., Boscutti, G., Caridi, G., Lugani, F., Ghiggeri, G. M., Coppo, R., Peruzzi, L., Esposito, V., Esposito, C., Feriozzi, S., Polci, R., Frasca, G., Galliani, M., Garozzo, M., Mitrotti, A., Gesualdo, L., Granata, S., Zaza, G., Londrino, F., Magistroni, R., Pisani, I., Magnano, A., Marcantoni, C., Messa, P., Mignani, R., Pani, A., Ponticelli, C., Roccatello, D., Salvadori, M., Salvi, E., Santoro, D., Gembillo, G., Savoldi, S., Spotti, D., Zamboli, P., Izzi, C., Alberici, F., Delbarba, E., Florczak, M., Krata, N., Mucha, K., Pączek, L., Niemczyk, S., Moszczuk, B., Pańczyk-Tomaszewska, M., Mizerska-Wasiak, M., Perkowska-Ptasińska, A., Bączkowska, T., Durlik, M., Pawlaczyk, K., Sikora, P., Zaniew, M., Kaminska, D., Krajewska, M., Kuzmiuk-Glembin, I., Heleniak, Z., Bullo-Piontecka, B., Liberek, T., Dębska-Slizien, A., Hryszko, T., Materna-Kiryluk, A., Miklaszewska, M., Szczepańska, M., Dyga, K., Machura, E., Siniewicz-Luzeńczyk, K., Pawlak-Bratkowska, M., Tkaczyk, M., Runowski, D., Kwella, N., Drożdż, D., Habura, I., Kronenberg, F., Prikhodina, L., van Heel, D., Fontaine, B., Cotsapas, C., Wijmenga, C., Franke, A., Annese, V., Gregersen, P. K., Parameswaran, S., Weirauch, M., Kottyan, L., Harley, J. B., Suzuki, H., Narita, I., Goto, S., Lee, H., Kim, D. K., Kim, Y. S., Park, J. H., Cho, B. L., Choi, M., Van Wijk, A., Huerta, A., Ars, E., Ballarin, J., Lundberg, S., Vogt, B., Mani, L. Y., Caliskan, Y., Barratt, J., Abeygunaratne, T., Kalra, P. A., Gale, D. P., Panzer, U., Rauen, T., Floege, J., Schlosser, P., Ekici, A. B., Eckardt, K. U., Chen, N., Xie, J., Lifton, R. P., Loos, Ruth, Kenny, E. E., Ionita-Laza, I., Köttgen, A., Julian, B. A., Novak, J., Scolari, F., Zhang, H. & Gharavi, A. G., 2023, In: Nature Genetics. 55, 7, p. 1091-1105 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Discrepancy between predicted and measured exercise intensity for eliciting the maximal rate of lipid oxidation

    Kittrell, H. D., DiMenna, F. J., Arad, A. D., Oh, W., Hofer, I., Walker, R. W., Loos, Ruth, Albu, J. B. & Nadkarni, G. N., 2023, In: Nutrition, Metabolism and Cardiovascular Diseases. 33, 11, p. 2189-2198

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Markers of Glucagon Resistance Improve With Reductions in Hepatic Steatosis and Body Weight in Type 2 Diabetes

    Kjeldsen, Sasha Alexandra Sampson, Thomsen, M. N., Skytte, M. J., Samkani, A., Richter, Michael Martin, Frystyk, J., Magkos, Faidon, Hansen, E., Thomsen, Henrik S., Holst, Jens Juul, Madsbad, Sten, Haugaard, Steen Bendix, Krarup, T. & Albrechtsen, Nicolai Jacob Wewer, 2023, In: Journal of the Endocrine Society. 7, 11, 11 p., bvad122.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Development of a glucagon sensitivity test in humans: Pilot data and the GLUSENTIC study protocol

    Kjeldsen, S. A. S., Richter, M. M., Jensen, N. J., Nilsson, M. S. D., Heinz, N., Nybing, J. D., Linden, F. H., Høgh-Schmidt, E., Boesen, M. P., Madsbad, S., Vilstrup, H., Schiødt, F. V., Møller, A., Nørgaard, K., Schmidt, S., Rashu, E. B., Gluud, L. L., Haugaard, S. B., Holst, J. J., Rungby, J. & 1 others, Albrechtsen, Nicolai Jacob Wewer, 2023, In: Peptides. 161, 10 p., 170938.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Neprilysin activity is increased in metabolic dysfunction-associated steatotic liver disease and normalizes after bariatric surgery or GLP-1 therapy

    Kjeldsen, S. A. S., Gluud, L. L., Werge, M. P., Pedersen, J. S., Bendtsen, F., Alexiadou, K., Tan, T., Torekov, S. S., Iepsen, E. W., Jensen, N. J., Richter, M. M., Goetze, J. P., Rungby, J., Hartmann, B., Holst, J. J., Holst, B., Holt, J., Gustafsson, F., Madsbad, S., Svane, M. S. & 2 others, Bojsen-Møller, K. N. & Albrechtsen, Nicolai Jacob Wewer, 2023, In: iScience. 26, 11, 13 p., 108190.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Migration mediated by the oxysterol receptor GPR183 depends on arrestin coupling but not receptor internalization

    Kjær, Viktoria Madeline Skovgaard, Daugvilaite, V., Stepniewski, T. M., Madsen, C. M., Jørgensen, Astrid Sissel, Bhuskute, K. R., Inoue, A., Ulven, Trond, Benned-Jensen, T., Hjorth, Siv Annegrethe, Hjortø, Gertrud Malene, Moo, Ee Von, Selent, J. & Rosenkilde, Mette, 2023, In: Science Signaling. 16, 779, 13 p., eabl4283.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    TBC1D4-S711 controls skeletal muscle insulin sensitization after exercise and contraction

    Kjøbsted, Rasmus, Kristensen, Jonas Møller, Eskesen, N. O., Kido, K., Fjorder, Klara, Damgaard, D. F., Larsen, Jeppe Kjærgaard, Andersen, Nicoline Resen, Birk, Jesper Bratz, Gudiksen, Anders, Treebak, Jonas Thue, Schjerling, Peter, Pilegaard, Henriette & Wojtaszewski, Jørgen F P, 2023, In: Diabetes. 72, 7, p. 857-871 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Cross-species comparison of pregnancy-induced GDF15

    Klein, A. B., Ranea-Robles, Pablo, Nicolaisen, T. S., Gil, Cláudia, Johann, K., Prats Quesada, Júlia, Pistoljevic, N., Hviid, K. V. R., Olsen, L. F., Offersen, Simone Margaard, Helge, Jørn Wulff, Nielsen, Henriette Svarre, Bakker, J., Kleinert, Maximilian & Clemmensen, Christoffer, 2023, In: American Journal of Physiology - Endocrinology and Metabolism. 325, 4, p. E303-E309

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    AMPKα2 is a skeletal muscle stem cell intrinsic regulator of myonuclear accretion

    Kneppers, A., Ben Larbi, S., Theret, M., Saugues, A., Dabadie, C., Gsaier, L., Ferry, A., Rhein, P., Gondin, J., Sakamoto, Kei & Mounier, R., 2023, In: iScience. 26, 12, 17 p., 108343.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    The Prevalence of Polyneuropathy in Type 2 Diabetes Subgroups Based on HOMA2 Indices of β-Cell Function and Insulin Sensitivity

    Kristensen, F. P. B., Christensen, D. H., Callaghan, B. C., Stidsen, J. V., Nielsen, J. S., Højlund, K., Beck-Nielsen, H., Jensen, T. S., Andersen, H., Vestergaard, P., Jessen, N., Olsen, M. H., Hansen, Torben, Brøns, C., Vaag, Allan, Sørensen, H. T. & Thomsen, R. W., 2023, In: Diabetes Care. 46, 8, p. 1546-1555 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    The naturally occurring GIP(1-30)NH2 is a GIP receptor agonist in humans

    Krogh, L. S. L., Henriksen, K., Stensen, S., Skov-Jeppesen, Kirsa, Bergmann, N. C., Størling, Joachim, Rosenkilde, Mette, Hartmann, Bolette, Holst, Jens Juul, Gasbjerg, Lærke Smidt & Knop, Filip Krag, 2023, In: European Journal of Endocrinology. 188, 1, lvac015.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Atorvastatin for patients with cirrhosis. A randomized, placebo-controlled trial

    Kronborg, T. M., Schierwagen, R., Trošt, K., Gao, Q., Moritz, Thomas, Bendtsen, Flemming, Gantzel, R. H., Andersen, M. L., Teisner, A. S., Grønbæk, H., Hobolth, L., Møller, Søren, Trebicka, J. & Kimer, N., 2023, In: Hepatology Communications. 7, 12, 11 p., e0332.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    GWAS of random glucose in 476,326 individuals provide insights into diabetes pathophysiology, complications and treatment stratification

    Lagou, V., Jiang, L., Ulrich, A., Zudina, L., González, K. S. G., Balkhiyarova, Z., Faggian, A., Maina, J. G., Chen, S., Todorov, P. V., Sharapov, S., David, A., Marullo, L., Mägi, R., Rujan, R. M., Ahlqvist, E., Thorleifsson, G., Gao, Η., Εvangelou, Ε., Benyamin, B. & 78 others, Scott, R. A., Isaacs, A., Zhao, J. H., Willems, S. M., Johnson, T., Gieger, C., Grallert, H., Meisinger, C., Müller-Nurasyid, M., Strawbridge, R. J., Goel, A., Rybin, D., Albrecht, E., Jackson, A. U., Stringham, H. M., Corrêa, I. R., Farber-Eger, E., Steinthorsdottir, V., Uitterlinden, A. G., Munroe, P. B., Brown, M. J., Schmidberger, J., Holmen, O., Thorand, B., Hveem, K., Wilsgaard, T., Mohlke, K. L., Wang, Z., den Hoed, M., Shmeliov, A., den Hoed, M., Loos, Ruth, Kratzer, W., Haenle, M., Koenig, W., Boehm, B. O., Tan, T. M., Tomas, A., Salem, V., Barroso, I., Tuomilehto, J., Boehnke, M., Florez, J. C., Hamsten, A., Watkins, H., Njølstad, I., Wichmann, H. E., Caulfield, M. J., Khaw, K. T., van Duijn, C. M., Hofman, A., Wareham, N. J., Langenberg, C., Whitfield, J. B., Martin, N. G., Montgomery, G., Scapoli, C., Tzoulaki, I., Elliott, P., Thorsteinsdottir, U., Stefansson, K., Brittain, E. L., McCarthy, M. I., Froguel, P., Sexton, P. M., Wootten, D., Groop, L., Dupuis, J., Meigs, J. B., Deganutti, G., Demirkan, A., Pers, Tune H, Reynolds, C. A., Aulchenko, Y. S., Kaakinen, M. A., Jones, B., Prokopenko, I. & van Duijn, C. M., 2023, In: Nature Genetics. 55, 9, p. 1448-1461 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Sex differences in muscle protein expression and DNA methylation in response to exercise training

    Landen, S., Jacques, M., Hiam, D., Alvarez-Romero, J., Schittenhelm, R. B., Shah, A. D., Huang, C., Steele, J. R., Harvey, N. R., Haupt, L. M., Griffiths, L. R., Ashton, K. J., Lamon, S., Voisin, S. & Eynon, N., 2023, In: Biology of Sex Differences. 14, 20 p., 56.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Self-organized metabotyping of obese individuals identifies clusters responding differently to bariatric surgery

    Lappa, D., Meijnikman, A. S., Krautkramer, K. A., Olsson, L. M., Aydin, Ö., Van Rijswijk, A. S., Acherman, Y. I. Z., De Brauw, M. L., Tremaroli, V., Olofsson, L. E., Lundqvist, A., Hjorth, Siv Annegrethe, Ji, B., Gerdes, V. E. A., Groen, A. K., Schwartz, Thue W., Nieuwdorp, M., Bäckhed, F. & Nielsen, J., 2023, In: PLoS ONE. 18, 3, 26 p., e0279335.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    High-throughput proteomics uncovers exercise training and type 2 diabetes-induced changes in human white adipose tissue

    Larsen, Jeppe Kjærgaard, Kruse, R., Sahebekhtiari, N., Moreno Justicia, Roger, Jorba, G. G., Petersen, M. H., de Almeida, M. E., Ørtenblad, N., Deshmukh, Atul Shahaji & Højlund, K., 2023, In: Science Advances. 9, 48, 16 p., eadi7548.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Oral glucose has little or no effect on appetite and satiety sensations despite a significant gastrointestinal response

    Lauritsen, J. V., Bergmann, N., Junker, A. E., Gyldenløve, Mette, Skov, Lone, Gluud, Lise Lotte, Hartmann, Bolette, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2023, In: European Journal of Endocrinology. 189, 6, p. 619-626 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Birth weight, childhood body mass index, and risk of diverticular disease in adulthood

    Laursen, A. S. D., Jensen, B. W., Strate, L. L., Sørensen, Thorkild I.A., Baker, J. L. & Sørensen, H. T., 2023, In: International Journal of Obesity. 47, p. 207–214 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    A single-cell, time-resolved profiling of Xenopus mucociliary epithelium reveals nonhierarchical model of development

    Lee, J., Møller, A. F., Chae, S., Bussek-Sedzinski, Alexandra Maria, Park, T. J., Kim, Y., Lee, H. S., Pers, Tune H, Kwon, T., Sedzinski, Jakub & Natarajan, K. N., 2023, In: Science Advances. 9, 14, p. eadd5745 23 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Editorial: Healthy adipose tissue expansion

    Lee, K. Y., Emanuelli, Brice & Ussar, S., 2023, In: Frontiers in Cell and Developmental Biology. 11, 3 p., 1287533.

    Research output: Contribution to journal › Editorial › Research

  46. Published

    Ancestral diversity in lipoprotein(a) studies helps address evidence gaps

    Lee, M. P., Dimos, S. F., Raffield, L. M., Wang, Z., Ballou, A. F., Downie, C. G., Arehart, C. H., Correa, A., De Vries, P. S., Du, Z., Gignoux, C. R., Gordon-Larsen, P., Guo, X., Haessler, J., Howard, A. G., Hu, Y., Kassahun, H., Kent, S. T., Lopez, J. A. G., Monda, K. L. & 14 others, North, K. E., Peters, U., Preuss, M. H., Rich, S. S., Rhodes, S. L., Yao, J., Yarosh, R., Tsai, M. Y., Rotter, J. I., Kooperberg, C. L., Loos, Ruth, Ballantyne, C., Avery, C. L. & Graff, M., 2023, In: Open Heart. 10, 2, 11 p., e002382.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Effects of different doses of exercise and diet-induced weight loss on beta-cell function in type 2 diabetes (DOSE-EX): a randomized clinical trial

    Legaard, G. E., Lyngbæk, M. P. P., Almdal, T. P., Karstoft, K., Bennetsen, S. L., Feineis, C. S., Nielsen, N. S., Durrer, C. G., Liebetrau, B., Nystrup, U., Østergaard, M., Thomsen, K., Trinh, B., Solomon, T. P. J., Van Hall, G., Brønd, J. C., Holst, J. J., Hartmann, B., Christensen, R., Pedersen, B. K. & 1 others, Ried-Larsen, M., 2023, In: Nature Metabolism. 5, p. 880–895

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Fungi and bacteria in the beds of rural and urban infants correlate with later risk of atopic diseases

    Lehtimäki, J., Gupta, S., Hjelmsø, M., Shah, S., Thorsen, Jonathan Jan Ilve, Rasmussen, Morten Arendt, Soverini, M., Li, Xuan Ji, Russel, J., Trivedi, Urvish, Brix, S., Bønnelykke, Klaus, Chawes, Bo Lund Krogsgaard, Bisgaard, H., Sørensen, Søren Johannes & Stokholm, Jakob, 2023, In: Clinical and Experimental Allergy. 53, 12, p. 1268-1278 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Molecular Consequences of Peripheral Influenza A Infection on Cell Populations in the Murine Hypothalamus

    Lemcke, René, Jensen, Christine Egebjerg, Pagh-Berendtsen, Nicolai, Egerod, Kristoffer Lihme, Thomsen, Allan Randrup, Pers, Tune H, Christensen, Jan Pravsgaard & Kornum, Birgitte Rahbek, 2023, 31 p.

    Research output: Working paper › Preprint › Research

  50. Published

    Molecular consequences of peripheral Influenza A infection on cell populations in the murine hypothalamus

    Lemcke, René, Jensen, Christine Egebjerg, Pagh-Berendtsen, Nicolai, Egerod, Kristoffer Lihme, Thomsen, Allan Randrup, Pers, Tune H, Christensen, Jan Pravsgaard & Kornum, Birgitte Rahbek, 2023, In: eLife. 12, 28 p., RP87515.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    The effect of traditional diet on glucose homeostasis in carriers and non-carriers of a common TBC1D4 variant in Greenlandic Inuit: A randomized crossover study

    Lewis, Jack Ivor, Lind, M. V., Møller, G., Hansen, Torben, Pedersen, H., Christensen, M. M. B., Laursen, J. C., Nielsen, S., Ottendahl, C. B., Larsen, C. V. L., Stark, K. D., Bjerregaard, P., Jørgensen, M. E. & Lauritzen, Lotte, 2023, In: British Journal of Nutrition. 130, 11, p. 1871-1884

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Improving Mitochondrial Function in Skeletal Muscle Contributes to the Amelioration of Insulin Resistance by Nicotinamide Riboside

    Li, Q., Jiang, Xuye, Zhou, Y., Gu, Y., Ding, Y., Luo, J., Pang, N., Sun, Y., Pei, L., Pan, J., Gao, M., Ma, S., Xiao, Y., Hu, D., Wu, F. & Yang, L., 2023, In: International Journal of Molecular Sciences. 24, 12, 19 p., 10015.

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    A statistical framework for powerful multi-trait rare variant analysis in large-scale whole-genome sequencing studies

    Li, X., Chen, H., Selvaraj, M. S., Van Buren, E., Zhou, H., Wang, Y., Sun, R., McCaw, Z. R., Yu, Z., Arnett, D. K., Bis, J. C., Blangero, J., Boerwinkle, E., Bowden, D. W., Brody, J. A., Cade, B. E., Carson, A. P., Carlson, J. C., Chami, N., Chen, Y-D. I. & 31 others, Curran, J. E., de Vries, P. S., Fornage, M., Franceschini, N., Freedman, B. I., Gu, C., Heard-Costa, N. L., He, J., Hou, L., Hung, Y., Irvin, M. R., Kaplan, R. C., Kardia, S. L. R., Kelly, T., Konigsberg, I., Kooperberg, C., Kral, B. G., Li, C., Loos, Ruth, Mahaney, M. C., Martin, L. W., Mathias, R. A., Minster, R. L., Mitchell, B. D., Montasser, M. E., Morrison, A. C., Palmer, N. D., Peyser, P. A., Psaty, B. M., Raffield, L. M. & NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, N. T. F. P. M. (. C., 2023, bioRxiv, 71 p.

    Research output: Working paper › Preprint › Research

  54. Published

    In Vitro Screening for Probiotic Properties of Lactobacillus and Bifidobacterium Strains in Assays Relevant for Non-Alcoholic Fatty Liver Disease Prevention

    Lopez-Escalera, S., Lund, M. L., Hermes, G. D. A., Choi, Beatrice So-Yun, Sakamoto, Kei & Wellejus, A., 2023, In: Nutrients. 15, 10, 23 p., 2361.

    Research output: Contribution to journal › Journal article › Research › peer-review

  55. Published

    Glucagon-like peptide-1 receptor agonists: role in the prevention and treatment of diabetes-related cardiovascular complications

    Lubberding, Anniek Frederike, Holst, Jens Juul & Madsbad, Sten, 2023, Cardiovascular Endocrinology and Metabolism: Theory and Practice of Cardiometabolic Medicine. Elsevier, p. 365-396

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  56. Published

    Ketolysis drives CD8+ T cell effector function through effects on histone acetylation

    Luda, K. M., Longo, J., Kitchen-Goosen, S. M., Duimstra, L. R., Ma, E. H., Watson, M. J., Oswald, B. M., Fu, Z., Madaj, Z., Kupai, A., Dickson, B. M., DeCamp, L. M., Dahabieh, M. S., Compton, S. E., Teis, R., Kaymak, I., Lau, K. H., Kelly, D. P., Puchalska, P., Williams, K. S. & 7 others, Krawczyk, C. M., Lévesque, D., Boisvert, F. M., Sheldon, R. D., Rothbart, S. B., Crawford, P. A. & Jones, R. G., 2023, In: Immunity. 56, 9, p. 2021-2035.e8 24 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  57. Published

    Childhood Obesity at the Crossroads of Science and Social Justice

    Ludwig, D. S. & Holst, Jens Juul, 2023, In: JAMA. 329, 22, p. 1909-1910

    Research output: Contribution to journal › Editorial › Research

  58. Published

    Is lactate a driver of skin burn-induced adipose browning?

    Lund, Jens, Johansen, Valdemar Brimnes Ingemann, Clemmensen, Christoffer & Gerhart-Hines, Zach, 2023, In: American Journal of Physiology - Endocrinology and Metabolism. 325, 4, p. E421-E422 2 p.

    Research output: Contribution to journal › Comment/debate › Research

  59. Published

    Overlooked confounding in studies of metabolite salts

    Lund, Jens, Clemmensen, Christoffer & Gerhart-Hines, Zach, 2023, In: Nature Metabolism. 5, 4, p. 542-543 2 p.

    Research output: Contribution to journal › Comment/debate › Research

  60. Published

    Physiological protection against weight gain: evidence from overfeeding studies and future directions

    Lund, Jens & Clemmensen, Christoffer, 2023, In: Philosophical transactions of the Royal Society of London. Series B, Biological sciences. 378, 1885, 11 p., 2022.0229.

    Research output: Contribution to journal › Review › Research › peer-review

  61. Published

    The anorectic and thermogenic effects of pharmacological lactate in male mice are confounded by treatment osmolarity and co-administered counterions

    Lund, J., Breum, A. W., Gil, C., Falk, S., Sass, F., Isidor, M. S., Dmytriyeva, O., Ranea-Robles, P., Mathiesen, C. V., Basse, A. L., Johansen, O. S., Fadahunsi, N., Lund, C., Nicolaisen, T. S., Klein, A. B., Ma, T., Emanuelli, B., Kleinert, M., Sørensen, C. M., Gerhart-Hines, Z. & 1 others, Clemmensen, Christoffer, 2023, In: Nature Metabolism. 5, 4, p. 677-698 22 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  62. Published

    Tracing the biological roots of obesity resistance in humans

    Lund, Jens, 2023, In: Nature Reviews Endocrinology. 19, p. 500 1 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  63. Published

    Lactate receptor GPR81 drives breast cancer growth and invasiveness through regulation of ECM properties and Notch ligand DLL4

    Jørgensen, Kathrine Lundø, Dmytriyeva, O., Spøhr, L., Alves, Eliana Carolina Goncalves, Yao, Jiayi, Puig Blasco, Laia, Trauelsen, Mette, Ponniah, M., Severin, M., Sandelin, Albin Gustav, Kveiborg, Marie, Schwartz, Thue W. & Pedersen, Stine Helene Falsig, 2023, In: BMC Cancer. 23, 1, 20 p., 1136.

    Research output: Contribution to journal › Journal article › Research › peer-review

  64. Published

    Biomarkers reflecting pericellular fibrosis improve together with liver histology after bariatric surgery in early non-alcoholic fatty liver disease

    Lønsmann, I., Pedersen, J. S., Krag, A., Hansen, Torben, Karsdal, M., Julie Leeming, D., Juul Nielsen, M. & Bendtsen, Flemming, 2023, In: Clinical Biochemistry. 113, p. 29-35 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  65. Published

    Cardiovascular effects of incretins - focus on glucagon-like peptide-1 receptor agonists

    Madsbad, Sten & Holst, Jens Juul, 2023, In: Cardiovascular Research. p. 886–904 19 p.

    Research output: Contribution to journal › Review › Research › peer-review

  66. Published

    Does glucose lowering restore GIP's effect on insulin secretion?

    Madsbad, Sten, Knop, Filip Krag & Holst, Jens Juul, 2023, In: Nutrition, Metabolism & Cardiovascular Diseases. 33, 9, p. 1817-1818

    Research output: Contribution to journal › Comment/debate › Research

  67. Published

    Insulinotropic effect of endogenously secreted incretins after gastric bypass and sleeve gastrectomy

    Madsbad, Sten & Holst, Jens Juul, 2023, In: Obesity. 31, 11, p. 2723-2724 2 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  68. Published

    Deciphering specificity and cross-reactivity in tachykinin NK1 and NK2 receptors

    Madsen, J. J., Petersen, Jacob Emil, Christensen, D. P., Hansen, J. B., Schwartz, Thue W., Frimurer, Thomas Michael & Olsen, O. H., 2023, In: Journal of Biological Chemistry. 299, 12, 11 p., 105438.

    Research output: Contribution to journal › Journal article › Research › peer-review

  69. Published

    Unravelling Effects of Rosemary (Rosmarinus officinalis L.) Extract on Hepatic Fat Accumulation and Plasma Lipid Profile in Rats Fed a High-Fat Western-Style Diet

    Madsen, S., Bak, S. Y., Yde, C. C., Jensen, H. M., Knudsen, T. A., Bæch-Laursen, C., Holst, Jens Juul, Laustsen, C. & Hedemann, M. S., 2023, In: Metabolites. 13, 9, 21 p., 974.

    Research output: Contribution to journal › Journal article › Research › peer-review

  70. Published

    6α-hydroxylated bile acids mediate TGR5 signalling to improve glucose metabolism upon dietary fiber supplementation in mice

    Makki, K., Brolin, H., Petersen, N., Henricsson, M., Christensen, D. P., Khan, M. T., Wahlström, A., Bergh, P., Tremaroli, V., Schoonjans, K., Marschall, H. & Bäckhed, F., 2023, In: Gut. 72, p. 314-324 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  71. Published

    Schizophrenia-associated somatic copy-number variants from 12,834 cases reveal recurrent NRXN1 and ABCB11 disruptions

    Maury, E. A., Sherman, M. A., Genovese, G., Gilgenast, T. G., Kamath, T., Burris, S. J., Rajarajan, P., Flaherty, E., Akbarian, S., Chess, A., McCarroll, S. A., Loh, P. R., Phillips-Cremins, J. E., Brennand, K. J., Macosko, E. Z., Walters, J. T. R., O'Donovan, M., Sullivan, P., Werge, T., Pers, T. H. & 2 others, Brain Somatic Mosaicism Network, B. S. M. N. & Psychiatric Genomic Consortium Schizophrenia and CNV workgroup, P. G. C. S. A. C. W., 2023, In: Cell Genomics. 3, 8, 22 p., 100356.

    Research output: Contribution to journal › Journal article › Research › peer-review

  72. Published

    Effects of levothyroxine substitution therapy on hunger and food intake in individuals with hypothyroidism

    Medici, B. R., Nygaard, Birte, la Cour, J. L., Krakauer, M., Brønden, Andreas, Sonne, M. P., Holst, Jens Juul, Rehfeld, Jens Frederik, Vilsbøll, Tina, Faber, J. & Knop, Filip Krag, 2023, In: Endocrine Connections. 12, 10, 14 p., e230314.

    Research output: Contribution to journal › Journal article › Research › peer-review

  73. Published

    Rare Heterozygous Loss-of-Function Variants in the Human GLP-1 Receptor Are Not Associated With Cardiometabolic Phenotypes

    Melchiorsen, Josefine Ulrikke, Sørensen, Kimmie Vestergaard, Bork-Jensen, J., Kizilkaya, Hüsün Sheyma, Gasbjerg, Lærke Smidt, Hauser, Alexander Sebastian, Rungby, Jørgen, Sørensen, H. T., Vaag, Allan, Nielsen, J. S., Pedersen, Oluf Borbye, Linneberg, Allan René, Hartmann, Bolette, Gjesing, A. P., Holst, Jens Juul, Hansen, Torben, Rosenkilde, Mette & Grarup, Niels, 2023, In: Journal of Clinical Endocrinology and Metabolism. 108, 11, p. 2821–2833 38 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  74. Published

    Genetic predisposition to macronutrient preference and workplace food choices

    Merino, Jordi, Dashti, H. S., Levy, D. E., Del Rocío Sevilla-González, M., Hivert, M. F., Porneala, B. C., Saxena, R. & Thorndike, A. N., 2023, In: Molecular Psychiatry. 28, 9, p. 2606–2611

    Research output: Contribution to journal › Review › Research › peer-review

  75. Published

    A Danish national, multicentre evaluation of the new donor vigilance system among different staff groups

    Mikkelsen, Christina, Paarup, H. M., Bruun, M. T., Pedersen, L. Ø., Hasslund, S., Larsen, R., Aagaard, B. & Sørensen, B. S., 2023, In: Vox Sanguinis. 118, 2, p. 121-127

    Research output: Contribution to journal › Journal article › Research › peer-review

  76. Published

    Diminishing benefits of urban living for children and adolescents’ growth and development

    Mishra, A., Zhou, B., Rodriguez-Martinez, A., Bixby, H., Baker, J. L., Afzal, S., Allin, K., Andersen, L. B., Ängquist, L., Jørgensen, M. B., Bjerregaard, P., Bojesen, S. E., Christensen, K., Damsgaard, C. T., Dantoft, T. M., Eliasen, M., Eriksen, L., Halkjær, J., Giwercman, A., Jørgensen, T. & 19 others, Kristensen, P. L., Lind, L., Linneberg, Allan René, Madsen, A. L., Michaelsen, Kim F., Møllehave, Line Tang, Mortensen, Erik Lykke, Nordestgaard, Børge, Osler, Merete, Overvad, K., Schmidt, I. M., Schnohr, P., Schramm, S., Sodemann, M., Sørensen, Thorkild I.A., Tjønneland, Anne, Tolstrup, J. S., Wang, Q. & NCD Risk Factor Collaboration (NCD-RisC), N. R. F. C. (., 2023, In: Nature. 615, 7954, p. 874-883 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  77. Published

    RNA sequencing unravels novel L cell constituents and mechanisms of GLP-1 secretion in human gastric bypass-operated intestine

    Miskelly, M. G., Lindqvist, A., Piccinin, E., Hamilton, A., Cowan, E., Nergård, B. J., Del Giudice, R., Ngara, M., Cataldo, L. R., Kryvokhyzha, D., Volkov, P., Engelking, L., Artner, I., Lagerstedt, J. O., Eliasson, L., Ahlqvist, E., Moschetta, A., Hedenbro, J. & Wierup, N., 2023, In: Diabetologia. 67, 2, p. 356-370

    Research output: Contribution to journal › Journal article › Research › peer-review

  78. Published

    Precision subclassification of type 2 diabetes: a systematic review

    Misra, S., Wagner, R., Ozkan, B., Schön, M., Sevilla-Gonzalez, M., Prystupa, K., Wang, C. C., Kreienkamp, R. J., Cromer, S. J., Rooney, M. R., Duan, D., Thuesen, A. C. B., Wallace, A. S., Leong, A., Deutsch, A. J., Andersen, M. K., Billings, L. K., Eckel, R. H., Sheu, W. H-H., Hansen, T. & 8 others, Stefan, N., Goodarzi, M. O., Ray, D., Selvin, E., Florez, J. C., Meigs, J. B., Udler, M. S. & ADA/EASD PMDI, A. P., 2023, In: Communications Medicine. 3, 19 p., 138.

    Research output: Contribution to journal › Journal article › Research › peer-review

  79. Published

    Microbially Produced Imidazole Propionate Is Associated With Heart Failure and Mortality

    Molinaro, A., Nemet, I., Bel Lassen, P., Chakaroun, R., Nielsen, T., Aron-Wisnewsky, J., Bergh, P. O., Li, L., Henricsson, M., Køber, Lars Valeur, Isnard, R., Helft, G., Stumvoll, M., Pedersen, Oluf Borbye, Smith, J. G., Tang, W. H. W., Clément, K., Hazen, S. L., Bäckhed, F. & MetaCardis Consortium, M. C., 2023, In: JACC: Heart Failure. 11, 7, p. 810-821 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  80. Published

    Pre-diabetes is associated with attenuation rather than volume of epicardial adipose tissue on computed tomography

    Molnar, D., Björnson, E., Larsson, M., Adiels, M., Gummesson, A., Bäckhed, F., Hjelmgren, O. & Bergström, G., 2023, In: Scientific Reports. 13, 1, 12 p., 1623.

    Research output: Contribution to journal › Journal article › Research › peer-review

  81. Published

    Genetic prediction of 33 blood group phenotypes using an existing genotype dataset

    Moslemi, C., Sækmose, S. G., Larsen, R., Bay, J. T., Brodersen, T., Didriksen, M., Hjalgrim, H., Banasik, K., Nielsen, K. R., Bruun, M. T., Dowsett, J., Dinh, K. M., Mikkelsen, S., Mikkelsen, C., Hansen, T. F., Ullum, H., Erikstrup, C., Brunak, S., Krogfelt, K. A., Storry, J. R. & 3 others, Ostrowski, Sisse Rye, Olsson, M. L. & Pedersen, Ole Birger Vesterager, 2023, In: Transfusion. 63, 12, p. 2297-2310 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  82. Published

    High anti-SARS-CoV-2 seroprevalence among unvaccinated mother-child pairs from a rural setting of north-eastern Tanzania during the second wave of COVID-19

    Msemo, O. A., Pérez-Alós, L., Minja, D. T. R., Hansen, Cecilie Bo, Gesase, S., Mtove, G., Mbwana, J., Larsen, V. M. L., Bøgestad, E. C. S., Grunnet, Louise Groth, Christensen, Dirk Lund, Bygbjerg, Ib Christian, Burgner, D., Schmiegelow, Christentze, Garred, Peter & Hjort, Line, 2023, In: IJID Regions (Online). 6, p. 48-57 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  83. Published

    Markers of inflammation predict survival in newly diagnosed cirrhosis: a prospective registry study

    Mynster Kronborg, T., Webel, Henry, O’Connell, M. B., Danielsen, K. V., Hobolth, L., Møller, Søren, Jensen, Rasmus Tanderup, Bendtsen, Flemming, Hansen, Torben, Rasmussen, Simon, Juel, H. B. & Kimer, N., 2023, In: Scientific Reports. 13, 11 p., 20039.

    Research output: Contribution to journal › Journal article › Research › peer-review

  84. Published

    Assessing household lifestyle exposures from consumer purchases, the My Purchases cohort

    Møller, F. T., Junker, T. G., Sørensen, Kathrine Kold, Eves, C., Wohlfahrt, J., Dillner, J., Torp-Pedersen, Christian, Wilkowski, B., Chong, S., Pers, Tune H, Yakimov, V., Müller, H., Ethelberg, Steen & Melbye, M., 2023, In: Scientific Reports. 13, 12 p., 21601.

    Research output: Contribution to journal › Journal article › Research › peer-review

  85. Published

    Rationale and design of a prospective, clinical study of kidney biopsies in people with type 2 diabetes and severely increased albuminuria (the PRIMETIME 2 study)

    Møller, M., Borg, Rikke, Bressendorff, I., Fink, L. N., Gravesen, E., Jensen, K. H., Hansen, Torben, Krustrup, D., Persson, F., Rossing, Peter, Sembach, F. E., Thuesen, Anne Cathrine Baun & Hansen, Ditte, 2023, In: BMJ Open. 13, 6, e072216.

    Research output: Contribution to journal › Journal article › Research › peer-review

  86. Published

    Effects of glepaglutide, a long-acting glucagon-like peptide-2 analog, on intestinal morphology and perfusion in patients with short bowel syndrome: Findings from a randomized phase 2 trial

    Naimi, R. M., Hvistendahl, M. K., Poulsen, Steen Seier, Kissow, Hannelouise, Pedersen, Jens, Nerup, N. A., Ambrus, R., Achiam, Michael Patrick, Svendsen, Lars Bo & Jeppesen, Palle Bekker, 2023, In: Journal of Parenteral and Enteral Nutrition. 47, 1, p. 140-150

    Research output: Contribution to journal › Journal article › Research › peer-review

  87. Published

    CaMKK2 is not involved in contraction-stimulated AMPK activation and glucose uptake in skeletal muscle

    Negoita, F., Addinsall, A. B., Hellberg, K., Bringas, C. F., Hafen, P. S., Sermersheim, T. J., Agerholm, M., Lewis, C. T. A., Ahwazi, D., Ling, N. X. Y., Larsen, J. K., Deshmukh, A. S., Hossain, M. A., Oakhill, J. S., Ochala, J., Brault, J. J., Sankar, U., Drewry, D. H., Scott, J. W., Witczak, C. A. & 1 others, Sakamoto, Kei, 2023, In: Molecular Metabolism. 75, 14 p., 101761.

    Research output: Contribution to journal › Journal article › Research › peer-review

  88. Published

    Liraglutide changes postprandial responses of gut hormones involved in the regulation of gallbladder motility

    Nerild, H. H., Brønden, Andreas, Gether, I. M., Hellmann, P. H., Baekdal, M., Gillum, M. P., Svenningsen, J. S., Hartmann, Bolette, Rathor, N., Kudiyanur Muniraju, H. A., Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina, Sonne, David Peick & Knop, Filip Krag, 2023, In: Diabetes, Obesity and Metabolism. 25, 6, p. 1632-1637

    Research output: Contribution to journal › Journal article › Research › peer-review

  89. Published

    Dasiglucagon Treatment for Postprandial Hypoglycemia After Gastric Bypass: A Randomized, Double-Blind, Placebo-Controlled Trial

    Nielsen, C. K., Øhrstrøm, C. C., Houji, I. J. K., Helsted, M. M., Krogh, L. S. L., Johansen, N. J., Hartmann, Bolette, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2023, In: Diabetes Care. 46, 12, p. 2208-2217 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  90. Published

    Hepatoprotective effects of the long-acting fibroblast growth factor 21 analog PF-05231023 in the GAN diet-induced obese and biopsy-confirmed mouse model of nonalcoholic steatohepatitis

    Nielsen, M. H., Gillum, M. P., Vrang, N., Jelsing, J., Hansen, H. H., Feigh, M. & Oró, D., 2023, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 324, 5, p. G378-G388 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  91. Published

    Appetite stimulation with cannabis-based medicine and methods for assessment of glomerular filtration in older patients with medical illness: A study protocol

    Nielsen, R. L., Bornæs, O., Storgaard, I. K., Kallemose, T., Jørgensen, L. M., Jawad, B. N., Altintas, I., Juul-larsen, H. G., Tavenier, J., Durhuus, J. A., Bengaard, A. K. P., Holst, J. J., Kolko, M., Sonne, D. P., Breindahl, T., Damgaard, M., Porrini, E., Hornum, M., Andersen, O., Pedersen, M. M. & 6 others, Rasmussen, H. H., Munk, T., Lund, Trine Meldgaard, Jensen, A. P. S. L., Andersen, A. L. & Houlind, Morten Baltzer, 2023, In: Basic & Clinical Pharmacology & Toxicology. 133, 3, p. 237-253 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  92. Published

    Developmental language disorder – a comprehensive study of more than 46,000 individuals

    Nudel, R., Christensen, Rikke Vang, Kalnak, N., Schwinn, M., Banasik, Karina, Dinh, K. M., Erikstrup, C., Pedersen, Ole Birger Vesterager, Burgdorf, Kristoffer Sølvsten, Ullum, H., Ostrowski, Sisse Rye, Hansen, Thomas Folkmann, Werge, Thomas & DBDS Genomic Consortium, D. G. C., 2023, In: Psychiatry Research. 323, 9 p., 115171.

    Research output: Contribution to journal › Journal article › Research › peer-review

  93. Published

    The national child odontology registry (SCOR): a valuable resource for odontological and public health research

    Nygaard, Nikoline, Ängquist, Lars, Midjord-Belstrøm, Daniel, Stankevic, Evelina, Hansen, Torben, Olsen, A., Rosing, Kasper & Markvart, Merete, 2023, In: BMC Oral Health. 23, 13 p., 608.

    Research output: Contribution to journal › Journal article › Research › peer-review

  94. Published

    Association between pain intensity and depressive symptoms in community-dwelling adults: longitudinal findings from the Survey of Health, Ageing and Retirement in Europe (SHARE)

    Ogliari, G., Ryg, J., Andersen-Ranberg, K., Scheel-Hincke, L. L., Collins, J. T., Cowley, A., Di Lorito, C., Booth, V., Smit, Roelof Adriaan Johan, Akyea, R. K., Qureshi, N., Walsh, D. A., Harwood, R. H. & Masud, T., 2023, In: European Geriatric Medicine. 14, 5, p. 1111-1124 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  95. Published

    Quality of life, patient satisfaction, and cardiovascular outcomes of the randomised 2 x 3 factorial Copenhagen insulin and Metformin therapy (CIMT) trial – A detailed statistical analysis plan

    Olsen, M. H., Almdal, Thomas Peter, Madsbad, Sten, Ovesen, C., Gluud, C., Sneppen, S. B., Breum, Leif, Hedetoft, C., Krarup, T., Lundby-Christensen, L., Mathiesen, Elisabeth, Røder, M. E., drb459, drb459, Wiinberg, N. & Jakobsen, J. C., 2023, In: Contemporary Clinical Trials Communications. 33, 101095.

    Research output: Contribution to journal › Journal article › Research › peer-review

  96. Published

    A literature review of evidence for primary prevention of overweight and obesity in healthy weight children and adolescents: A report produced by a working group of the Danish Council on Health and Disease Prevention

    Olsen, N. J., Østergaard, J. N., Bjerregaard, L. G., Høy, T. V., Kierkegaard, L., Michaelsen, Kim F., Sørensen, Thorkild I.A., Grønbæk, M. K., Bruun, J. M. & Heitmann, Berit, 2023, In: Obesity Reviews. 25, 1, 10 p., e13641.

    Research output: Contribution to journal › Review › Research › peer-review

  97. Published

    De-novo reconstruction and identification of transcriptional gene regulatory network modules differentiating single-cell clusters

    Oubounyt, M., Elkjaer, M. L., Laske, T., Grønning, Alexander GB, Moeller, M. J. & Baumbach, J., 2023, In: NAR Genomics and Bioinformatics. 5, 1, 17 p., lqad018.

    Research output: Contribution to journal › Journal article › Research › peer-review

  98. Published

    The effect of diabetes and the diabetogenic TBC1D4 p.Arg684ter variant on kidney function in Inuit in Greenland

    Overvad, M., Díaz, L. J., Bjerregaard, P., Pedersen, M. L., Larsen, C. V. L., Grarup, Niels, Hansen, Torben, Rossing, Peter & Jørgensen, M. E., 2023, In: International Journal of Circumpolar Health. 82, 8 p., 2191406.

    Research output: Contribution to journal › Journal article › Research › peer-review

  99. Published

    Sugar- or artificially-sweetened beverage consumption, physical activity, and risk of cardiovascular disease in US adults

    Pacheco, L. S., Tobias, D. K., Li, Y., Bhupathiraju, S. N., Willett, W. C., Ludwig, D. S., Ebbeling, C. B., Haslam, D. E., Drouin-Chartier, J., Hu, F. B. & Guasch Ferre, Marta, 2023, medRxiv, 29 p.

    Research output: Working paper › Preprint › Research

  100. Published

    Adipogenic and SWAT cells separate from a common progenitor in human brown and white adipose depots

    Palani, Nagendra Prasad, Horvath, C., Timshel, P. N., Folkertsma, P., Grønning, Alexander GB, Henriksen, T. I., Peijs, Lone, Jensen, V. H., Sun, W., Jespersen, N. Z., Wolfrum, C., Pers, Tune H, Nielsen, S. & Schéele, Camilla Charlotte Nielsen, 2023, In: Nature Metabolism. 5, 6, p. 996-1013 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  101. Published

    New therapies for obesity

    Papamargaritis, D., le Roux, C. W., Holst, Jens Juul & Davies, M. J., 2023, In: Cardiovascular Research. 119, 18, p. 2825–2842

    Research output: Contribution to journal › Review › Research › peer-review

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