Novo Nordisk Foundation Center for Basic Metabolic Research

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  1. 2023
  2. Published

    Standard procedures for blood withdrawal in conscious male rats induce stress and profoundly affect glucose tolerance and secretion of glucoregulatory hormones

    Pedersen, K., Andersen, H., Fledelius, C., Holst, Jens Juul, Hjuler, S. T. & Kuhre, Rune Ehrenreich, 2023, In: Molecular Metabolism. 69, 101689.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Emergence of the obesity epidemic preceding the presumed obesogenic transformation of the society

    Pedersen, M. M., Ekstrøm, Claus Thorn & Sørensen, Thorkild I.A., 2023, In: Science Advances. 9, 37, 7 p., eadg6237.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Targeted Delivery of Butyrate Improves Glucose Homeostasis, Reduces Hepatic Lipid Accumulation and Inflammation in db/db Mice

    Pedersen, Signe Schultz, Prause, Michala Cecilie Burstein, Sørensen, C., Størling, Joachim, Moritz, Thomas, Mariño, E. & Billestrup, Nils, 2023, In: International Journal of Molecular Sciences. 24, 5, 17 p., 4533.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Oral supplementation of nicotinamide riboside alters intestinal microbial composition in rats and mice, but not humans

    Peluso, A. A., Lundgaard, A. T., Babaei, P., Mousovich-Neto, F., Rocha, A. L., Damgaard, M. V., Bak, E. G., Gnanasekaran, T., Dollerup, O. L., Trammell, S. A. J., Nielsen, T. S., Kern, T., Abild, C. B., Sulek, K., Ma, T., Gerhart-Hines, Z., Gillum, M. P., Arumugam, M., Ørskov, C., McCloskey, D. & 4 others, Jessen, N., Herrgård, M. J., Mori, M. A. S. & Treebak, Jonas Thue, 2023, In: npj Aging. 9, 21 p., 7.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Functional assay for assessment of agonistic or antagonistic activity of angiotensin AT2 receptor ligands reveals that EMA401 and PD123319 have agonistic properties

    Peluso, A. A., Souza-Silva, I. M., Villela, D. C., Hansen, P. B. L., Hallberg, A., Bader, M., Santos, R., Sumners, C. & Steckelings, U. M., 2023, In: Biochemical Pharmacology. 216, 12 p., 115793.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Time of day determines postexercise metabolism in mouse adipose tissue

    Pendergrast, L. A., Lundell, L. S., Ehrlich, Amy M, Ashcroft, Stephen Paul, Schönke, M., Basse, A. L., Krook, A., Treebak, Jonas Thue, Dollet, L. & Zierath, Juleen R, 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 8, e2218510120.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Free fatty acid receptor 1 stimulates cAMP production and gut hormone secretion through Gq-mediated activation of adenylate cyclase 2

    Petersen, Jacob Emil, Pedersen, M. H., Dmytriyeva, O., Nellemose, E., Arora, Tulika, Engelstoft, M. S., Asher, W. B., Javitch, J. A., Schwartz, Thue W. & Trauelsen, Mette, 2023, In: Molecular Metabolism. 74, 10 p., 101757.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Endosomal egress and intercellular transmission of hepatic ApoE-containing lipoproteins and its exploitation by the hepatitis C virus

    Pham, M., Lee, J., Ritter, C., Thielemann, Roman, Meyer, J., Haselmann, U., Funaya, C., Laketa, V., Rohr, K. & Bartenschlager, R., 2023, In: PLoS Pathogens. 19, 7, 40 p., e1011052.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    TNIK is a conserved regulator of glucose and lipid metabolism in obesity

    Pham, Tang Cam Phung, Dollet, L., Ali, Mona Sadek, Raun, Steffen Henning, Møller, Lisbeth L V, Jafari Kermani, Abbas, Ditzel, N., Andersen, Nicoline Resen, Fritzen, Andreas Mæchel, Gerhart-Hines, Zach, Kiens, Bente, Suomalainen, A., Simpson, S. J., Salling Olsen, M., Kieser, A., Schjerling, Peter, Nieminen, A. I., Richter, Erik A., Havula, E. & Sylow, Lykke, 2023, In: Science Advances. 9, 32, 18 p., eadf7119.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Interwoven challenges of covid-19, poor diet, and cardiometabolic health

    Piernas, C. & Merino, Jordi, 2023, In: BMJ. 383, 5 p., 076810.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Transcriptional and epigenomic profiling identifies YAP signaling as a key regulator of intestinal epithelium maturation

    Pikkupeura, Laura Maarit, Bardini Bressan, Raul, Guiu, J., Chen, Y., Maimets, Martti, Mayer, Daniela, Schweiger, P. J., Hansen, Stine Lind, Maciag, Grzegorz Jerzy, Larsen, Hjalte List, Lõhmussaar, Kadi, Pedersen, M. T., Teves, Joji Marie Yap, Lange, Jette Bornholdt, Benes, V., Sandelin, Albin Gustav & Jensen, Kim Bak, 2023, In: Science Advances. 9, 28, 16 p., eadf9460.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Commensal bacteria weaken the intestinal barrier by suppressing epithelial neuropilin-1 and Hedgehog signaling

    Pontarollo, G., Kollar, B., Mann, A., Khuu, M. P., Kiouptsi, K., Bayer, F., Brandão, I., Zinina, V. V., Hahlbrock, J., Malinarich, F., Mimmler, M., Bhushan, S., Marini, F., Ruf, W., Belheouane, M., Baines, J. F., Endres, K., Reba, S. M., Raker, V. K., Deppermann, C. & 8 others, Welsch, C., Bosmann, M., Soshnikova, N., Chassaing, B., Bergentall, M., Sommer, F., Bäckhed, F. & Reinhardt, C., 2023, In: Nature Metabolism. 5, 7, p. 1174-1187 25 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Reuniting philosophy and science to advance cancer research

    Pradeu, T., Daignan-Fornier, B., Ewald, A., Germain, P. L., Okasha, S., Plutynski, A., Benzekry, S., Bertolaso, M., Bissell, M., Brown, J. S., Chin-Yee, B., Chin-Yee, I., Clevers, H., Cognet, L., Darrason, M., Farge, E., Feunteun, J., Galon, J., Giroux, E., Green, S. & 18 others, Gross, F., Jaulin, F., Knight, R., Laconi, E., Larmonier, N., Maley, C., Mantovani, A., Moreau, V., Nassoy, P., Rondeau, E., Santamaria, D., Sawai, C. M., Seluanov, A., Sepich-Poore, G. D., Sisirak, V., Solary, E., Yvonnet, Sarah & Laplane, L., 2023, In: Biological Reviews. 98, p. 1668-1686 19 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Post-prandial secretion of glucagon-like peptide-2 (GLP-2) after carbohydrate-, fat- or protein enriched meals in healthy subjects

    Prahm, A. P., Hvistendahl, M. K., Brandt, Christopher Filtenborg, Blanche, Paul Frédéric, Hartmann, Bolette, Holst, Jens Juul & Jeppesen, Palle Bekker, 2023, In: Peptides. 169, 8 p., 171091.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Effects of acute exercise and exercise training on plasma GDF15 concentrations and associations with appetite and cardiometabolic health in individuals with overweight or obesity – A secondary analysis of a randomized controlled trial

    Quist, Jonas Salling, Klein, A. B., Færch, K., Beaulieu, K., Rosenkilde, M., Gram, A. S., Sjödin, Anders Mikael, Torekov, Signe Sørensen, Stallknecht, Bente Merete, Clemmensen, Christoffer & Blond, Martin Bæk, 2023, In: Appetite. 182, 11 p., 106423.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Meal sugar-protein balance determines postprandial FGF21 response in humans

    Ramne, Stina, Duizer, Lisanne, Nielsen, M. S., Jørgensen, Niklas Rye, Svenningsen, J. S., Grarup, Niels, Sjödin, Anders Mikael, Raben, Anne & Gillum, M. P., 2023, In: American Journal of Physiology - Endocrinology and Metabolism. 325, 5, p. E491-E499

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    The biochemistry and physiology of long-chain dicarboxylic acid metabolism

    Ranea-Robles, Pablo & Houten, S. M., 2023, In: Biochemical Journal. 480, 9, p. 607-627 21 p.

    Research output: Contribution to journal › Review › Research › peer-review

  19. Published

    Preanalytical impact on the accuracy of measurements of glucagon, GLP-1 and GIP in clinical trials

    Rasmussen, C., Richter, Michael Martin, Jensen, N. J., Heinz, N., Hartmann, Bolette, Holst, Jens Juul, Kjeldsen, Sasha Alexandra Sampson & Albrechtsen, Nicolai Jacob Wewer, 2023, In: Scandinavian Journal of Clinical and Laboratory Investigation. 83, 8, p. 591-598

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Metabolic Profiling Early Post-Allogeneic Haematopoietic Cell Transplantation in the Context of CMV Infection

    Rasmussen, K. K., dos Santos, Q., MacPherson, C. R., Zucco, Adrian G., Gjærde, L. K., Ilett, Emma Elizabeth, Lodding, I., Helleberg, Marie, Lundgren, Jens, Nielsen, S. D., Brix, S., Sengeløv, Henrik & Murray, D. D., 2023, In: Metabolites. 13, 9, 11 p., 968.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Circulating Amino Acids and Risk of Peripheral Artery Disease in the PREDIMED Trial

    Razquin, C., Ruiz-Canela, M., Toledo, E., Clish, C. B., Guasch-Ferré, M., García-Gavilán, J. F., Wittenbecher, C., Alonso-Gómez, A., Fitó, M., Liang, L., Corella, D., Gómez-Gracia, E., Estruch, R., Fiol, M., Santos-Lozano, J. M., Serra-Majem, L., Ros, E., Aros, F., Salas-Salvadó, J., Hu, F. B. & 1 others, Martínez-González, M. A., 2023, In: International Journal of Molecular Sciences. 24, 12 p., 270.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    The influence of insulin-related genetic variants on fetal growth, fetal blood flow, and placental weight in a prospective pregnancy cohort

    Reim, Pauline Kromann, pjx571, pjx571, Gybel-Brask, D., Schnurr, T. M., Kelstrup, Louise, Høgdall, Estrid Vilma Solyom & Hansen, Torben, 2023, In: Scientific Reports. 13, 10 p., 19638.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Postprandial secretion of follistatin after gastric bypass surgery and sleeve gastrectomy

    Richter, Michael Martin, Svane, M. S., Kristiansen, V. B., Holst, Jens Juul, Madsbad, Sten & Bojsen-Møller, K. N., 2023, In: Peptides. 163, 8 p., 170978.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Plasma metabolite profiles associated with the World Cancer Research Fund/American Institute for Cancer Research lifestyle score and future risk of cardiovascular disease and type 2 diabetes

    Rios, S., García-Gavilán, J. F., Babio, N., Paz-Graniel, I., Ruiz-Canela, M., Liang, L., Clish, C. B., Toledo, E., Corella, D., Estruch, R., Ros, E., Fitó, M., Arós, F., Fiol, M., Guasch-Ferré, M., Santos-Lozano, J. M., Li, J., Razquin, C., Martínez-González, M. Á., Hu, F. B. & 1 others, Salas-Salvadó, J., 2023, In: Cardiovascular Diabetology. 22, 13 p., 252.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Hyperglucagonaemia and amino acid alterations in individuals with type 2 diabetes and non-alcoholic fatty liver disease

    Rix, I., Johansen, M. L., Lund, A., Suppli, M. P., Chabanova, E., van Hall, Gerrit, Holst, Jens Juul, Albrechtsen, Nicolai Jacob Wewer, Kistorp, Caroline Michaela Nervil & Knop, Filip Krag, 2023, In: Endocrine Connections. 13, 1, 11 p., e230161.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Monoamines' role in islet cell function and type 2 diabetes risk

    Roberts, F. L., Cataldo, L. R. & Fex, M., 2023, In: Trends in Molecular Medicine. 29, 12, p. 1045-1058 14 p.

    Research output: Contribution to journal › Review › Research › peer-review

  27. Published

    Metabolism and Art

    Rogers, Hannah Star & Bencard, Adam, 2023, In: Leonardo. 56, 4, p. 388–390 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Full activation of thermogenesis in brown adipocytes requires Basigin action

    Rupar, K., Isidor, Marie Sophie, Argemi Muntadas, Lidia, Agueda Oyarzabal, Marina, Plucinska, Kaja, Brown, E. L., Mattanovich, M., Bossi, Simone, Tozzi, M., Tandio, David, Petersen, P. S. S., Henriksen, T. I., Trošt, K., Hansen, Jacob B., Gerhart-Hines, Zach, Nielsen, S., Moritz, Thomas & Emanuelli, Brice, 2023, In: F E B S Journal. 290, 10, p. 2673-2691

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Clostridium scindens secretome suppresses virulence gene expression of Clostridioides difficile in a bile acid-independent manner

    Saenz, C., Fang, Q., Gnanasekaran, Thiyagarajan, Trammell, Sam, Buijink, June D.A., Pisano, P., Wierer, M., Moens, F., Lengger, B., Brejnrod, A. & Arumugam, Mani, 2023, In: Microbiology Spectrum. 11, 5, p. 1-18 e0393322.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Combination of exercise and GLP-1 receptor agonist treatment reduces severity of metabolic syndrome, abdominal obesity, and inflammation: a randomized controlled trial

    Sandsdal, Rasmus Michael, Juhl, C. R., Jensen, Simon Birk Kjær, Lundgren, J. R., Janus, C., Blond, Martin Bæk, Rosenkilde, M., Bogh, A. F., Gliemann, Lasse, Jensen, Jens-Erik Beck, Antoniades, C., Stallknecht, Bente Merete, Holst, Jens Juul, Madsbad, Sten & Torekov, Signe Sørensen, 2023, In: Cardiovascular Diabetology. 22, 1, 12 p., 41.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    FOXO3A-short is a novel regulator of non-oxidative glucose metabolism associated with human longevity

    Santo, E. E., Ribel-Madsen, R., Stroeken, P. J., de Boer, V. C. J., Hansen, N. S., Commandeur, M., Vaag, Allan, Versteeg, R., Paik, J. & Westerhout, E. M., 2023, In: Aging Cell. 22, 3, 13 p., e13763.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Changes in adult obesity prevalence in Denmark, 1987-2021: age-period-cohort analysis of nationally representative data

    Schramm, S., Sørensen, Thorkild I.A., Davidsen, M. & Tolstrup, J. S., 2023, In: European Journal of Public Health. 33, 3, p. 463–467 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Approaching diagnostic messiness through spiderweb strategies: Connecting epistemic practices in the clinic and the laboratory

    Scott-Fordsmand, Helene & Tybjerg, Karin, 2023, In: Studies in History and Philosophy of Science. 102, p. 12-21 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Genetic Loss of Sucrase-Isomaltase Function: Mechanisms, Implications, and Future Perspectives

    Senftleber, N. K., Ramne, Stina, Moltke, Ida, Jørgensen, M. E., Albrechtsen, Anders, Hansen, Torben & Lepola, Mette Andersen, 2023, In: Application of Clinical Genetics. 16, p. 31-39 9 p.

    Research output: Contribution to journal › Review › Research › peer-review

  35. Published

    The effect of sucrase-isomaltase deficiency on metabolism, food intake and preferences: protocol for a dietary intervention study

    Senftleber, N. K., Pedersen, K. S., Schnoor Jørgensen, C., Pedersen, H., Bjerg Christensen, M. M., Kabel Madsen, E., Andersen, K., Jørsboe, E., Gillum, M. P., Frøst, Michael Bom, Hansen, Torben & Jørgensen, M. E., 2023, In: International Journal of Circumpolar Health. 82, 1, 10 p., 2178067.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Expanding known viral diversity in the healthy infant gut

    Shah, S. A., Deng, L., Thorsen, J., Pedersen, A. G., Dion, M. B., Castro-Mejía, J. L., Silins, R., Romme, F. O., Sausset, R., Jessen, L. E., Ndela, E. O., Hjelmsø, M., Rasmussen, M. A., Redgwell, T. A., Rodríguez, C. L., Vestergaard, G., Zhang, Y., Chawes, B., Bønnelykke, K., Sørensen, S. J. & 6 others, Bisgaard, H., Enault, F., Stokholm, Jakob, Moineau, S., Petit, M. A. & Nielsen, Dennis Sandris, 2023, In: Nature Microbiology. 8, p. 986–998

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Absence of gut microbiota reduces neonatal survival and exacerbates liver disease in Cyp2c70-deficient mice with a human-like bile acid composition

    Sjöland, W., Wahlström, A., Makki, K., Schöler, M., Molinaro, A., Olsson, L., Greiner, T. U., Caesar, R., de Boer, J. F., Kuipers, F., Bäckhed, F. & Marschall, H. U., 2023, In: Clinical Science. 137, 13, p. 995-1011 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    GDF15 increases insulin action in the liver and adipose tissue via a β-adrenergic receptor-mediated mechanism

    Sjøberg, K. A., Sigvardsen, Casper Møller, Alvarado-Diaz, A., Andersen, Nicoline Resen, Larance, M., Seeley, R. J., Schjerling, Peter, Knudsen, Jakob Grunnet, Katzilieris Petras, Georgios, Clemmensen, Christoffer, Jørgensen, S. B., De Bock, K. & Richter, Erik A., 2023, In: Cell Metabolism. 35, 8, p. 1327-1340.e5 19 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Uncovering CNS access of lipidated exendin-4 analogues by quantitative whole-brain 3D light sheet imaging

    Skovbjerg, G., Roostalu, U., Salinas, C. G., Skytte, J. L., Perens, J., Clemmensen, Christoffer, Elster, L., Frich, C. K., Hansen, H. H. & Hecksher-Sørensen, J., 2023, In: Neuropharmacology. 238, 109637.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Multiancestry Genome-Wide Association Study of Aortic Stenosis Identifies Multiple Novel Loci in the Million Veteran Program

    Small, A. M., Peloso, G. M., Linefsky, J., Aragam, J., Galloway, A., Tanukonda, V., Wang, L. C., Yu, Z., Sunitha Selvaraj, M., Farber-Eger, E. H., Baker, M. T., Setia-Verma, S., Lee, S. S. K., Preuss, M., Ritchie, M. D., Damrauer, S. M., Rader, D. J., Wells, Q. S., Loos, R., Lubitz, S. A. & 5 others, Thanassoulis, G., Cho, K., Wilson, P. W. F., Natarajan, P. & O'Donnell, C. J., 2023, In: Circulation. 147, 12, p. 942-955 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Seasonal light hours modulate peripheral clocks and energy metabolism in mice

    Small, Lewin Barkla, Lundell, L. S., Iversen, Jo Frøkjær, Ehrlich, Amy M, Dall, M., Basse, A. L., Kellezi, Emilie Dalbram, Hansen, Ann Normann, Treebak, Jonas Thue, Barrès, Romain & Zierath, Juleen R, 2023, In: Cell Metabolism. 35, 10, p. 1722-1735.e5 20 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Exercise metabolism and adaptation in skeletal muscle

    Smith, J. A. B., Murach, K. A., Dyar, K. A. & Zierath, Juleen R, 2023, In: Nature Reviews Molecular Cell Biology. 24, p. 607-632

    Research output: Contribution to journal › Review › Research › peer-review

  43. Published

    Endogenous glucagon-like peptide (GLP)-1 as alternative for GLP-1 receptor agonists: Could this work and how?

    Smits, Mark & Holst, Jens Juul, 2023, In: Diabetes/Metabolism Research and Reviews. 39, 8, 17 p., e3699.

    Research output: Contribution to journal › Review › Research › peer-review

  44. Published

    ROS-induced ribosome impairment underlies ZAKα-mediated metabolic decline in obesity and aging

    Snieckute, G., Ryder, L., Vind, A. C., Wu, Z., Arendrup, F. S., Stoneley, M., Chamois, S., Martinez-Val, A., Leleu, M., Dreos, R., Russell, A., Gay, D. M., Genzor, A. V., Choi, B. S-Y., Basse, A. L., Sass, F., Dall, M., Dollet, L. C. M., Blasius, M., Willis, A. E. & 10 others, Lund, Anders H., Treebak, Jonas Thue, Olsen, Jesper Velgaard, Poulsen, Steen Seier, Pownall, M. E., Jensen, Benjamin Anderschou Holbech, Clemmensen, Christoffer, Gerhart-Hines, Zach, Gatfield, D. & Bekker-Jensen, Simon Holst, 2023, In: Science (New York, N.Y.). 382, 6675, 14 p., eadf3208.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Unanswered questions about the causes of obesity

    Speakman, J. R., Sørensen, Thorkild I.A., Hall, K. D. & Allison, D. B., 2023, In: Science. 381, 6661, p. 944-946 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    The contribution of functional HNF1A variants and polygenic susceptibility to risk of type 2 diabetes in ancestrally diverse populations

    Stalbow, L. A., Preuss, M. H., Smit, Roelof Adriaan Johan, Chami, N., Bjørkhaug, L., Aukrust, I., Gloyn, A. L. & Loos, Ruth, 2023, In: Diabetologia. 66, p. 116-126 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Binge drinking episode causes acute, specific alterations in systemic and hepatic inflammation-related markers

    Stankevic, Evelina, Israelsen, M., Juel, H. B., Madsen, Anne Lundager, Ängquist, Lars, Aldiss, Peter Stuart Jacob, Torp, N., Johansen, S., Hansen, C. D., Hansen, J. K., Thorhauge, K. H., Lindvig, K. P., Madsen, B. S., Sulek, K., Legido-Quigley, C., Thiele, M. S., Krag, A. & Hansen, Torben, 2023, In: Liver International. 43, 12, p. 2680–2691 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    High Plasma Levels of Soluble Lectin-like Oxidized Low-Density Lipoprotein Receptor-1 Are Associated With Inflammation and Cardiometabolic Risk Profiles in Pediatric Overweight and Obesity

    Stinson, Sara, Jonsson, Anna Elisabet, Lepola, Mette Andersen, Lund, Morten Asp Vonsild, Holm, L. A., Fonvig, Cilius Esmann, Huang, Yun, Stankevic, Evelina, Juel, H. B., Ängquist, Lars, Sørensen, Thorkild I.A., Ongstad, E. L., Gaddipati, R., Grimsby, J., Rhodes, C. J., Pedersen, Oluf Borbye, Christiansen, M., Holm, Jens-Christian & Hansen, Torben, 2023, In: Journal of the American Heart Association. 12, 3, p. 538-544 22 p., e8145.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Can breastfeeding promote an antibiotic-resilient microbiome?

    Stokholm, Jakob & Thorsen, Jonathan Jan Ilve, 2023, In: Med. 4, 2, p. 67-68 2 p.

    Research output: Contribution to journal › Comment/debate › Research

  50. Published

    Usefulness of Heat Map Explanations for Deep-Learning-Based Electrocardiogram Analysis

    Storås, A. M., Andersen, O. E., Lockhart, S., Thielemann, Roman, Gnesin, Filip Jurijevitj, Thambawita, Vajira Lasantha Bandara, Hicks, S. A., Kanters, Jørgen K., Strümke, I., Halvorsen, P. & Riegler, M. A., 2023, In: Diagnostics. 13, 14, 11 p., 2345.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    Multi-ancestry genome-wide study in >2.5 million individuals reveals heterogeneity in mechanistic pathways of type 2 diabetes and complications

    VA Million Veteran Program, V. M. V. P., 2023, medRxiv, 39 p.

    Research output: Working paper › Preprint › Research

  52. Published

    Overweight, Weight Loss and Self-reported Global Life Satisfaction: The Lolland-Falster Health Study

    Søby, S. F., Sørensen, Thorkild I.A., Jepsen, R. & Køster-Rasmussen, Rasmus, 2023, In: Obesity Facts. 16, 6, p. 567–575 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    An adiposity force induces obesity in humans independently of a normal energy balance system-a thought experiment

    Sørensen, Thorkild I.A., 2023, In: Philosophical transactions of the Royal Society of London. Series B, Biological sciences. 378, 1885, 9 p., 20220203.

    Research output: Contribution to journal › Review › Research › peer-review

  54. Published

    Sphingolipids Are Depleted in Alcohol-Related Liver Fibrosis

    Thiele, M., Suvitaival, T., Trošt, K., Kim, M., de Zawadzki, A., Kjaergaard, M., Rasmussen, D. N., Lindvig, K. P., Israelsen, M., Detlefsen, S., Andersen, P., Juel, H. B., Nielsen, T., Georgiou, S., Filippa, V., Kuhn, M., Nishijima, S., Moitinho-Silva, L., Rossing, P., Trebicka, J. & 14 others, Anastasiadou, E., Bork, P., Hansen, T., Legido-Quigley, C., Krag, A., Mann, M., Matthijnssens, J., Arumugam, Mani, Henrar, R., Israelsen, H., Karsdal, M., Melberg, H. O., MicrobLiver Consortium, M. C. & GALAXY Consortium, G. C., 2023, In: Gastroenterology. 164, 7, p. 1248-1260

    Research output: Contribution to journal › Journal article › Research › peer-review

  55. Published

    Alteration of Gut Microbiome in Patients With Schizophrenia Indicates Links Between Bacterial Tyrosine Biosynthesis and Cognitive Dysfunction

    Thirion, F., Speyer, H., Hansen, T. H., Nielsen, T., Fan, Y., Le Chatelier, E., Fromentin, S., Berland, M., Plaza Oñate, F., Pons, N., Galleron, N., Levenez, F., Markó, L., Birkner, T., Jørgensen, T., Forslund, S. K., Vestergaard, H., Hansen, T., Nordentoft, M., Mors, O. & 3 others, Benros, Michael Eriksen, Pedersen, Oluf Borbye & Ehrlich, S. D., 2023, In: Biological Psychiatry Global Open Science. 3, 2, p. 283-291 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  56. Published

    The gut microbiota in multiple sclerosis varies with disease activity

    Thirion, F., Sellebjerg, Finn Thorup, Fan, Yong, Lyu, Liwei, Hansen, T. H., Pons, N., Levenez, F., Quinquis, B., Stankevic, Evelina, Søndergaard, H. B., Dantoft, T. M., Poulsen, C. S., Forslund, S. K., drb459, drb459, Hansen, Torben, Brix, S., Oturai, A., Sørensen, Per Soelberg, Ehrlich, S. D. & Pedersen, Oluf Borbye, 2023, In: Genome Medicine. 15, 17 p., 1.

    Research output: Contribution to journal › Journal article › Research › peer-review

  57. Published

    Middle ear effusion, ventilation tubes and neurological development in childhood

    Thorsen, Jonathan Jan Ilve, Pedersen, T. M., Cecilie Mora-Jensen, A. R., Bjarnadó ttir, E., Bager, S. C., Bisgaard, H. & Stokholm, Jakob, 2023, In: PLoS ONE. 18, 1, 14 p., e0280199.

    Research output: Contribution to journal › Journal article › Research › peer-review

  58. Published

    A novel splice-affecting HNF1A variant with large population impact on diabetes in Greenland

    Thuesen, A. C. B., Stæger, F. F., Kaci, A., Solheim, M. H., Aukrust, I., Jørsboe, E., Santander, C. G., Andersen, M. K., Li, Z., Gilly, A., Stinson, S. E., Gjesing, A. P., Bjerregaard, P., Pedersen, M. L., Larsen, C. V. L., Grarup, N., Jørgensen, M. E., Zeggini, E., Bjørkhaug, L., Njølstad, P. R. & 3 others, Albrechtsen, Anders, Moltke, Ida & Hansen, Torben, 2023, In: The Lancet Regional Health - Europe. 24, 12 p., 100529.

    Research output: Contribution to journal › Journal article › Research › peer-review

  59. Published

    Genetics of metabolic traits in Greenlanders

    Thuesen, Anne Cathrine Baun, Lepola, Mette Andersen & Hansen, Torben, 2023, In: Danish Medical Journal. 70, 12, 9 p., A05230332.

    Research output: Contribution to journal › Review › Research › peer-review

  60. Published

    Identification of pathogenic GCK variants in patients with common type 2 diabetes can lead to discontinuation of pharmacological treatment

    Thuesen, Anne Cathrine Baun, Jensen, Rasmus Tanderup, Maagensen, H., Kristiansen, M. R., Sørensen, H. T., Vaag, Allan, Beck-Nielsen, H., Pedersen, Oluf Borbye, Grarup, Niels, Nielsen, J. S., Rungby, Jørgen, Gjesing, A. P., Storgaard, H., Vilsbøll, Tina & Hansen, Torben, 2023, In: Molecular Genetics and Metabolism Reports. 35, 8 p., 100972.

    Research output: Contribution to journal › Journal article › Research › peer-review

  61. Published

    Second international consensus report on gaps and opportunities for the clinical translation of precision diabetes medicine

    Tobias, D. K., Merino, J., Ahmad, A., Aiken, C., Benham, J. L., Bodhini, D., Clark, A. L., Colclough, K., Corcoy, R., Cromer, S. J., Duan, D., Felton, J. L., Francis, E. C., Gillard, P., Gingras, V., Gaillard, R., Haider, E., Hughes, A., Ikle, J. M., Jacobsen, L. M. & 180 others, Kahkoska, A. R., Kettunen, J. L. T., Kreienkamp, R. J., Lim, L. L., Männistö, J. M. E., Massey, R., Mclennan, N. M., Miller, R. G., Morieri, M. L., Most, J., Naylor, R. N., Ozkan, B., Patel, K. A., Pilla, S. J., Prystupa, K., Raghavan, S., Rooney, M. R., Schön, M., Semnani-Azad, Z., Sevilla-Gonzalez, M., Svalastoga, P., Takele, W. W., Tam, C. H. T., Thuesen, Anne Cathrine Baun, Tosur, M., Wallace, A. S., Wang, C. C., Wong, J. J., Yamamoto, J. M., Young, K., Amouyal, C., Lepola, Mette Andersen, Bonham, M. P., Chen, M., Cheng, F., Chikowore, T., Chivers, S. C., Clemmensen, Christoffer, Dabelea, D., Dawed, A. Y., Deutsch, A. J., Dickens, L. T., DiMeglio, L. A., Dudenhöffer-Pfeifer, M., Evans-Molina, C., Fernández-Balsells, M. M., Fitipaldi, H., Fitzpatrick, S. L., Gitelman, S. E., Goodarzi, M. O., Grieger, J. A., Guasch Ferre, Marta, Habibi, N., Hansen, Torben, Huang, C., Harris-Kawano, A., Ismail, H. M., Hoag, B., Johnson, R. K., Jones, A. G., Koivula, R. W., Leong, A., Leung, G. K. W., Libman, I. M., Liu, K., Long, S. A., Lowe, W. L., Morton, R. W., Motala, A. A., Onengut-Gumuscu, S., Pankow, J. S., Pathirana, M., Pazmino, S., Perez, D., Petrie, J. R., Powe, C. E., Quinteros, A., Jain, R., Ray, D., Ried-Larsen, M., Saeed, Z., Santhakumar, V., Kanbour, S., Sarkar, S., Monaco, G. S. F., Scholtens, D. M., Selvin, E., Sheu, W. H. H., Speake, C., Stanislawski, M. A., Steenackers, N., Steck, A. K., Stefan, N., Støy, J., Taylor, R., Tye, S. C., Ukke, G. G., Urazbayeva, M., Van der Schueren, B., Vatier, C., Wentworth, J. M., Hannah, W., White, S. L., Yu, G., Zhang, Y., Zhou, S. J., Beltrand, J., Polak, M., Aukrust, I., de Franco, E., Flanagan, S. E., Maloney, K. A., McGovern, A., Molnes, J., Nakabuye, Mariam, Njølstad, P. R., Pomares-Millan, H., Provenzano, M., Saint-Martin, C., Zhang, C., Zhu, Y., Auh, S., de Souza, R., Fawcett, A. J., Gruber, C., Mekonnen, E. G., Mixter, E., Sherifali, D., Eckel, R. H., Nolan, J. J., Philipson, L. H., Brown, R. J., Billings, L. K., Boyle, K., Costacou, T., Dennis, J. M., Florez, J. C., Gloyn, A. L., Gomez, M. F., Gottlieb, P. A., Greeley, S. A. W., Griffin, K., Hattersley, A. T., Hirsch, I. B., Hivert, M. F., Hood, K. K., Josefson, J. L., Kwak, S. H., Laffel, L. M., Lim, S. S., Loos, Ruth, Ma, R. C. W., Mathieu, C., Mathioudakis, N., Meigs, J. B., Misra, S., Mohan, V., Murphy, R., Oram, R., Owen, K. R., Ozanne, S. E., Pearson, E. R., Perng, W., Pollin, T. I., Pop-Busui, R., Pratley, R. E., Redman, L. M., Redondo, M. J., Reynolds, R. M., Semple, R. K., Sherr, J. L., Sims, E. K., Sweeting, A., Tuomi, T., Udler, M. S., Vesco, K. K., Vilsbøll, Tina, Wagner, R., Rich, S. S. & Franks, P. W., 2023, In: Nature Medicine. 29, 10, p. 2438-2457 20 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  62. Published

    Microbial dietary protein metabolism regulates GLP-1 mediated intestinal transit

    Toft, P. B., Yashiro, H., Erion, D. M., Gillum, M. P., Bäckhed, F. & Arora, Tulika, 2023, In: FASEB Journal. 37, 10, 8 p., e23201.

    Research output: Contribution to journal › Journal article › Research › peer-review

  63. Published

    Microbial metabolite p-cresol inhibits gut hormone expression and regulates small intestinal transit in mice

    Toft, P. B., Vanslette, A. M., Trošt, K., Moritz, Thomas, Gillum, M. P., Bäckhed, F. & Arora, Tulika, 2023, In: Frontiers in Endocrinology. 14, 7 p., 1200391.

    Research output: Contribution to journal › Journal article › Research › peer-review

  64. Published

    Optogenetic control of YAP can enhance the rate of wound healing

    Toh, Jia Ying Pearlyn, Sudol, M. & Saunders, T. E., 2023, In: Cellular and Molecular Biology Letters. 28, 17 p., 39.

    Research output: Contribution to journal › Letter › Research › peer-review

  65. Published

    Paracrine relationship between incretin hormones and endogenous 5-hydroxytryptamine in the small and large intestine

    Tough, I. R., Lund, M. L., Patel, B. A., Schwartz, Thue W. & Cox, H. M., 2023, In: Neurogastroenterology and Motility. 35, 8, 14 p., e14589.

    Research output: Contribution to journal › Journal article › Research › peer-review

  66. Published

    Sleep-Time eating boosts exercise endurance

    Treebak, Jonas Thue, 2023, In: Life Metabolism. 2, 5, 2 p., load029.

    Research output: Contribution to journal › Journal article › Research › peer-review

  67. Published

    Collections, Knowledge and Time

    Tybjerg, Karin (ed.) & Grünfeld, Martin (ed.), 2023, Belgium. 243 p. (Centaurus).

    Research output: Book/Report › Book › peer-review

  68. Published

    Genetics of Plasma Bilirubin and Associations between Bilirubin and Cardiometabolic Risk Profiles in Danish Children and Adolescents

    Ullah, A., Stankevic, Evelina, Holm, L. A., Stinson, Sara, Juel, H. B., Fonvig, Cilius Esmann, Lund, M. A. V., Trier, C., pjx571, pjx571, Ängquist, Lars, Jonsson, Anna Elisabet, Pedersen, Oluf Borbye, Grarup, Niels, Holm, Jens-Christian & Hansen, Torben, 2023, In: Antioxidants. 12, 8, 1613.

    Research output: Contribution to journal › Journal article › Research › peer-review

  69. Published

    Type 2 Diabetes risk alleles in Peptidyl-glycine Alpha-amidating Monooxygenase influence GLP-1 levels and response to GLP-1 Receptor Agonists

    Umapathysivam, M. M., Araldi, E., Hastoy, B., Dawed, A. Y., Vatandaslar, H., Sengupta, S., Kaufmann, A., Thomsen, S., Hartmann, B., Jonsson, A. E., Kabakci, H., Thaman, S., Grarup, N., Have, C. T., Færch, K., Gjesing, A. P., Nawaz, S., Cheeseman, J., Neville, M. J., Pedersen, O. & 12 others, Walker, M., Jennison, C., Hattersley, A. T., Hansen, Torben, Karpe, F., Holst, Jens Juul, Jones, A. G., Ristow, M., McCarthy, M. I., Pearson, E. R., Stoffel, M. & Gloyn, A. L., 2023, medRxiv, 35 p.

    Research output: Working paper › Preprint › Research

  70. Published

    Beta cell dysfunction induced by bone morphogenetic protein (BMP)-2 is associated with histone modifications and decreased NeuroD1 chromatin binding

    Urizar, A. I., Prause, Michala Cecilie Burstein, Ingerslev, L. R., Wortham, M., Sui, Y., Sander, M., Williams, K., Barrès, Romain, Larsen, M. R., Christensen, G. L. & Billestrup, Nils, 2023, In: Cell Death and Disease. 14, 7, 16 p., 399.

    Research output: Contribution to journal › Journal article › Research › peer-review

  71. Published

    Metabolic Dysregulation in Adult Survivors of Pediatric Hematopoietic Stem Cell Transplantation: The Role of Incretins

    Vadmand, A. C., Nissen, A. A., Mathiesen, S., Ebbesen, M. S., Gerbek, T., Fridh, M. K., Sørensen, K., Hartmann, Bolette, Holst, Jens Juul & Muller, Klaus, 2023, In: Journal of Clinical Endocrinology and Metabolism. 108, 2, p. 453–462

    Research output: Contribution to journal › Journal article › Research › peer-review

  72. Published

    Serotonin receptor 4 agonism prevents high fat diet induced reduction in GLP-1 in mice

    Vanslette, A. M., Toft, P. B., Lund, M. L., Moritz, Thomas & Arora, Tulika, 2023, In: European Journal of Pharmacology. 960, 176181.

    Research output: Contribution to journal › Journal article › Research › peer-review

  73. Published

    Genomic Disorders in CKD across the Lifespan

    Verbitsky, M., Krishnamurthy, S., Krithivasan, P., Hughes, D., Khan, A., Marasà, M., Vena, N., Khosla, P., Zhang, J., Lim, T. Y., Glessner, J. T., Weng, C., Shang, N., Shen, Y., Hripcsak, G., Hakonarson, H., Ionita-Laza, I., Levy, B., Kenny, E. E., Loos, R. J. F. & 11 others, Kiryluk, K., Sanna-Cherchi, S., Crosslin, D. R., Furth, S., Warady, B. A., Igo, R. P., Iyengar, S. K., Wong, C. S., Parsa, A., Feldman, H. I. & Gharavi, A. G., 2023, In: Journal of the American Society of Nephrology : JASN. 34, 4, p. 607-618 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  74. Published

    Gestational age at birth and body size from infancy through adolescence: An individual participant data meta-analysis on 253,810 singletons in 16 birth cohort studies

    Vinther, J. L., Cadman, T., Avraam, D., Ekstrøm, C. T., I A Sørensen, T., Elhakeem, A., Santos, A. C., Pinot de Moira, A., Heude, B., Iñiguez, C., Pizzi, C., Simons, E., Voerman, E., Corpeleijn, E., Zariouh, F., Santorelli, G., Inskip, H. M., Barros, H., Carson, J., Harris, J. R. & 27 others, Nader, J. L., Ronkainen, J., Strandberg-Larsen, Katrine, Santa-Marina, L., Calas, L., Kristiansen, Luise Cederkvist, Popovic, M., Charles, M., Welten, M., Vrijheid, M., Azad, M., Subbarao, P., Burton, P., Mandhane, P. J., Huang, R., Wilson, R. C., Haakma, S., Fernández-Barrés, S., Turvey, S., Santos, S., Tough, S. C., Sebert, S., Moraes, T. J., Salika, T., Jaddoe, V. W. V., Lawlor, D. A. & Nybo Andersen, Anne-Marie, 2023, In: PLoS Medicine. 20, 1, 27 p., e1004036.

    Research output: Contribution to journal › Journal article › Research › peer-review

  75. Published

    Gestational age and trajectories of body mass index and height from birth through adolescence in the Danish National Birth Cohort

    Vinther, Johan Lerbech, Ekstrøm, Claus Thorn, Sørensen, Thorkild I.A., Kristiansen, Luise Cederkvist, Lawlor, D. A. & Nybo Andersen, Anne-Marie, 2023, In: Scientific Reports. 13, 10 p., 3298.

    Research output: Contribution to journal › Journal article › Research › peer-review

  76. Published

    Increased Insulin Secretion and Glucose Effectiveness in Obese Patients with Type 2 Diabetes following Bariatric Surgery

    Visentin, R., Brodersen, K., Richelsen, B., Møller, N., Dalla Man, C., Pedersen, A. K., Abrahamsen, J., Holst, Jens Juul & Nielsen, M. F., 2023, In: Journal of Diabetes Research. 2023, 14 p., 127426.

    Research output: Contribution to journal › Journal article › Research › peer-review

  77. Published

    Whole exome sequencing identified a novel splice donor site variant in interleukin 2 receptor alpha chain

    Waheed, N., Naseer, M., Haider, N., Suleman, Sufyan & Ullah, A., 2023, In: Immunogenetics. 75, p. 71-79

    Research output: Contribution to journal › Journal article › Research › peer-review

  78. Published

    Plasma metabolomic profiles associated with mortality and longevity in a prospective analysis of 13,512 individuals

    Wang, F., Tessier, A. J., Liang, L., Wittenbecher, C., Haslam, D. E., Fernández-Duval, G., Heather Eliassen, A., Rexrode, K. M., Tobias, D. K., Li, J., Zeleznik, O., Grodstein, F., Martínez-González, M. A., Salas-Salvadó, J., Clish, C., Lee, K. H., Sun, Q., Stampfer, M. J., Hu, F. B. & Guasch Ferre, Marta, 2023, In: Nature Communications. 14, 1, 11 p., 5744.

    Research output: Contribution to journal › Journal article › Research › peer-review

  79. Published

    Meal timing of dietary total antioxidant capacity and its association with all-cause, CVD and cancer mortality: the US national health and nutrition examination survey, 1999–2018

    Wang, P., Jiang, Xuye, Tan, Q., Du, S. & Shi, D., 2023, In: International Journal of Behavioral Nutrition and Physical Activity. 20, 13 p., 83.

    Research output: Contribution to journal › Journal article › Research › peer-review

  80. Published

    Global Biobank analyses provide lessons for developing polygenic risk scores across diverse cohorts

    Wang, Y., Namba, S., Lopera-Maya, E. A., Kerminen, S., Tsuo, K., Läll, K., Kanai, M., Zhou, W., Wu, K. H. H., Favé, M. J., Bhatta, L., Awadalla, P., Brumpton, B. M., Deelen, P., Hveem, K., Lo Faro, V., Mägi, R., Murakami, Y., Sanna, S., Smoller, J. W. & 49 others, Uzunovic, J., Wolford, B. N., Wu, K. H. H., Rasheed, H., Hirbo, J. B., Bhattacharya, A., Zhao, H., Surakka, I., Lopera-Maya, E. A., Chapman, S. B., Karjalainen, J., Kurki, M., Mutaamba, M., Partanen, J. J., Brumpton, B. M., Chavan, S., Chen, T. T., Daya, M., Ding, Y., Feng, Y. C. A., Gignoux, C. R., Graham, S. E., Hornsby, W. E., Ingold, N., Johnson, R., Laisk, T., Lin, K., Lv, J., Millwood, I. Y., Loos, Ruth, BBJ, B., BioMe, B., BioVU, B., Canadian Partnership for Tomorrow's Health/OHS, C. P. F. T. H., China Kadoorie Biobank Collaborative Group, C. K. B. C. G., Colorado Center for Personalized Medicine, C. C. F. P. M., deCODE Genetics, D. G., ESTBB, E., FinnGen, F., Generation Scotland, G. S., Genes & Health, G. &. H., LifeLines, L., Mass General Brigham Biobank, M. G. B. B., Michigan Genomics Initiative, M. G. I., QIMR Berghofer Biobank, Q. B. B., Taiwan Biobank, T. B., The HUNT Study, T. H. S., UCLA ATLAS Community Health Initiative, U. A. C. H. I. & UKBB, U., 2023, In: Cell Genomics. 3, 1, 18 p., 100241.

    Research output: Contribution to journal › Journal article › Research › peer-review

  81. Published

    Rare variants in long non-coding RNAs are associated with blood lipid levels in the TOPMed whole-genome sequencing study

    Wang, Y., Selvaraj, M. S., Li, X., Li, Z., Holdcraft, J. A., Arnett, D. K., Bis, J. C., Blangero, J., Boerwinkle, E., Bowden, D. W., Cade, B. E., Carlson, J. C., Carson, A. P., Chen, Y. D. I., Curran, J. E., de Vries, P. S., Dutcher, S. K., Ellinor, P. T., Floyd, J. S., Fornage, M. & 31 others, Freedman, B. I., Gabriel, S., Germer, S., Gibbs, R. A., Guo, X., He, J., Heard-Costa, N., Hildalgo, B., Hou, L., Irvin, M. R., Joehanes, R., Kaplan, R. C., Kardia, S. L., Kelly, T. N., Kim, R., Kooperberg, C., Kral, B. G., Levy, D., Li, C., Liu, C., Lloyd-Jone, D., Loos, Ruth, Mahaney, M. C., Martin, L. W., Mathias, R. A., Minster, R. L., Mitchell, B. D., Montasser, M. E., Morrison, A. C., Murabito, J. M. & NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, N. T. F. P. M. (. C., 2023, In: American Journal of Human Genetics. 110, 10, p. 1704-1717 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  82. Published

    Distilling causality between physical activity traits and obesity via Mendelian randomization

    Wang, Z., Davey Smith, G., Loos, Ruth & den Hoed, M., 2023, In: Communications Medicine. 3, 6 p., 173.

    Research output: Contribution to journal › Journal article › Research › peer-review

  83. Published

    Molecular Connectomics Reveals a Glucagon-Like Peptide 1 Sensitive Neural Circuit for Satiety

    Webster, A. N., Becker, J. J., Li, C., Schwalbe, D. C., Kerspern, D., Karolczak, E. O., Godschall, E. N., Belmont-Rausch, Dylan Matthew, Pers, Tune H, Lutas, A., Habib, N., Güler, A. D., Krashes, M. J. & Campbell, J. N., 2023, bioRxiv, 47 p.

    Research output: Working paper › Preprint › Research

  84. Published

    Pregnancy-Associated Bleeding and Genetics: Five Sequence Variants in the Myometrium and Progesterone Signaling Pathway are associated with postpartum hemorrhage

    Westergaard, D., Steinthorsdottir, V., Stefansdottir, L., Rohde, P. D., Wu, X., Geller, F., Tyrmi, J., Havulinna, A. S., Navais, P. S., Flatley, C., Ostrowski, S. R., Pedersen, O. B., Erikstrup, C., Sørensen, E., Mikkelsen, C., Brun, M. T., Jensen, B. A., Brodersen, T., Ullum, H., Magnus, P. & 8 others, Andreassen, O. A., Njolstad, P. R., Krebs, Lone, Hansen, Thomas Folkmann, Banasik, Karina, Brunak, Søren, Nielsen, Henriette Svarre & FinnGen, F., 2023, medRxiv, 51 p. (medRxiv).

    Research output: Working paper › Preprint › Research

  85. Published

    100 years of glucagon and 100 more

    Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Cherrington, A. D., Finan, B., Gluud, Lise Lotte, Dean, E. D., Campbell, J. E., Bloom, S. R., Tan, T. M., Knop, Filip Krag & Müller, T. D., 2023, In: Diabetologia. 66, p. 1378–1394

    Research output: Contribution to journal › Review › Research › peer-review

  86. Published

    Low birthweight is associated with a higher incidence of type 2 diabetes over two decades independent of adult BMI and genetic predisposition

    Wibaek, R., Andersen, G. S., Linneberg, Allan René, Hansen, Torben, Grarup, Niels, Thuesen, Anne Cathrine Baun, Jensen, Rasmus Tanderup, Wells, J. C. K., Pilgaard, Kasper Ascanius, Brøns, C., Vistisen, D. & Vaag, Allan, 2023, In: Diabetologia. 66, p. 1669–1679 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  87. Published

    Genome-wide association study and functional characterization identifies candidate genes for insulin-stimulated glucose uptake

    Williamson, A., Norris, D. M., Yin, X., Broadaway, K. A., Moxley, A. H., Vadlamudi, S., Wilson, E. P., Jackson, A. U., Ahuja, V., Andersen, M. K., Arzumanyan, Z., Bonnycastle, L. L., Bornstein, S. R., Bretschneider, M. P., Buchanan, T. A., Chang, Y-C., Chuang, L-M., Chung, R-H., Clausen, T. D., Damm, P. & 31 others, Delgado, G. E., de Mello, V. D., Dupuis, J., Dwivedi, O. P., Erdos, M. R., Silva, L. F., Frayling, T. M., Gieger, C., Goodarzi, M. O., Guo, X., Gustafsson, S., Hakaste, L., Hammar, U., Hatem, G., Herrmann, S., Højlund, K., Horn, K., Jonsson, Anna Elisabet, Kovacs, P., Linneberg, Allan René, Mathiesen, Elisabeth, Friis, Carsten, Stinson, Sara, Suleman, Sufyan, Vistisen, D., Witte, D. R., Hansen, Torben, Lind, L., Schwarz, Peter, Grarup, Niels & Meta-Analysis of Glucose and Insulin-related Traits Consortium (MAGIC), M. O. G. A. I. T. C. (., 2023, In: Nature Genetics. 55, 6, p. 973-983 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  88. Published

    Hepatic Glucose Production, Ureagenesis, and Lipolysis Quantified using the Perfused Mouse Liver Model

    Winther-Sørensen, Marie, Kemp, I. M., Bisgaard, Hanne Cathrine, Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2023, In: Journal of Visualized Experiments. 2023, 200, e65596.

    Research output: Contribution to journal › Journal article › Research › peer-review

  89. Published

    Glucose Transport and Utilization in the Hippocampus: From Neurophysiology to Diabetes-Related Development of Dementia

    Yonamine, Caio Yogi, Michalani, M. L. E., Moreira, R. J. & Machado, U. F., 2023, In: International Journal of Molecular Sciences. 24, 22, 24 p., 16480.

    Research output: Contribution to journal › Review › Research › peer-review

  90. Published

    Postmortem Brains from Subjects with Diabetes Mellitus Display Reduced GLUT4 Expression and Soma Area in Hippocampal Neurons: Potential Involvement of Inflammation

    Yonamine, Caio Yogi, Passarelli, M., Suemoto, C. K., Pasqualucci, C. A., Jacob-Filho, W., Alves, V. A. F., Marie, S. K. N., Correa-Giannella, M. L., Britto, L. R. & Machado, U. F., 2023, In: Cells. 12, 9, 21 p., 1250.

    Research output: Contribution to journal › Journal article › Research › peer-review

  91. Published

    Genetic architecture of spatial electrical biomarkers for cardiac arrhythmia and relationship with cardiovascular disease

    Young, W. J., Haessler, J., Benjamins, J-W., Repetto, L., Yao, J., Isaacs, A., Harper, A. R., Ramirez, J., Garnier, S., van Duijvenboden, S., Baldassari, A. R., Concas, M. P., Duong, T., Foco, L., Isaksen, J. L., Mei, H., Noordam, R., Nursyifa, C., Richmond, A., Santolalla, M. L. & 74 others, Sitlani, C. M., Soroush, N., Thériault, S., Trompet, S., Aeschbacher, S., Ahmadizar, F., Alonso, A., Brody, J. A., Campbell, A., Correa, A., Darbar, D., De Luca, A., Deleuze, J., Ellervik, Christina, Fuchsberger, C., Goel, A., Grace, C., Guo, X., Hansen, Torben, Heckbert, S. R., Jackson, R. D., Kors, J. A., Lima-Costa, M. F., Linneberg, Allan René, Macfarlane, P. W., Morrison, A. C., Navarro, P., Porteous, D. J., Pramstaller, P. P., Reiner, A. P., Risch, L., Schotten, U., Shen, X., Sinagra, G., Soliman, E. Z., Stoll, M., Tarazona-Santos, E., Tinker, A., Trajanoska, K., Villard, E., Warren, H. R., Whitsel, E. A., Wiggins, K. L., Arking, D. E., Avery, C. L., Conen, D., Girotto, G., Grarup, Niels, Hayward, C., Jukema, J. W., Mook-Kanamori, D. O., Olesen, Morten Steen Salling, Padmanabhan, S., Psaty, B. M., Pattaro, C., Ribeiro, A. L. P., Rotter, J. I., Stricker, B. H., van der Harst, P., van Duijn, C. M., Verweij, N., Wilson, J. G., Orini, M., Charron, P., Watkins, H., Kooperberg, C., Lin, H. J., Wilson, J. F., Kanters, Jørgen K., Sotoodehnia, N., Mifsud, B., Lambiase, P. D., Tereshchenko, L. G. & Munroe, P. B., 14 Mar 2023, In: Nature Communications. 14, 1, 16 p., 1411.

    Research output: Contribution to journal › Journal article › Research › peer-review

  92. Published

    Causal factors underlying diabetes risk informed by Mendelian randomisation analysis: evidence, opportunities and challenges

    Yuan, S., Merino, Jordi & Larsson, S. C., 2023, In: Diabetologia. 66, p. 800-812 13 p.

    Research output: Contribution to journal › Review › Research › peer-review

  93. Published

    Estimation of Life's Essential 8 Score with Incomplete Data of Individual Metrics

    Zheng, Y., Huang, T., Guasch Ferre, Marta, Hart, J., Laden, F., Chavarro, J., Rimm, E., Coull, B. & Hu, H., 2023, In: Frontiers in Cardiovascular Medicine. 10, 11 p., 1216693.

    Research output: Contribution to journal › Journal article › Research › peer-review

  94. Published

    Gene-educational attainment interactions in a multi-population genome-wide meta-analysis identify novel lipid loci

    de las Fuentes, L., Schwander, K. L., Brown, M. R., Bentley, A. R., Winkler, T. W., Sung, Y. J., Munroe, P. B., Miller, C. L., Aschard, H., Aslibekyan, S., Bartz, T. M., Bielak, L. F., Chai, J. F., Cheng, C. Y., Dorajoo, R., Feitosa, M. F., Guo, X., Hartwig, F. P., Horimoto, A., Kolčić, I. & 178 others, Lim, E., Liu, Y., Manning, A. K., Marten, J., Musani, S. K., Noordam, R., Padmanabhan, S., Rankinen, T., Richard, M. A., Ridker, P. M., Smith, A. V., Vojinovic, D., Zonderman, A. B., Alver, M., Boissel, M., Christensen, K., Freedman, B. I., Gao, C., Giulianini, F., Harris, S. E., He, M., Hsu, F. C., Kühnel, B., Laguzzi, F., Li, X., Lyytikäinen, L. P., Nolte, I. M., Poveda, A., Rauramaa, R., Riaz, M., Robino, A., Sofer, T., Takeuchi, F., Tayo, B. O., van der Most, P. J., Verweij, N., Ware, E. B., Weiss, S., Wen, W., Yanek, L. R., Zhan, Y., Amin, N., Arking, D. E., Ballantyne, C., Boerwinkle, E., Brody, J. A., Broeckel, U., Campbell, A., Canouil, M., Chai, X., Chen, Y. D. I., Chen, X., Chitrala, K. N., Concas, M. P., de Faire, U., de Mutsert, R., de Silva, H. J., de Vries, P. S., Do, A., Faul, J. D., Fisher, V., Floyd, J. S., Forrester, T., Friedlander, Y., Girotto, G., Gu, C. C., Hallmans, G., Heikkinen, S., Heng, C. K., Homuth, G., Hunt, S., Ikram, M. A., Jacobs, D. R., Kavousi, M., Khor, C. C., Kilpeläinen, Tuomas O., Koh, W. P., Komulainen, P., Langefeld, C. D., Liang, J., Liu, K., Liu, J., Lohman, K., Mägi, R., Manichaikul, A. W., McKenzie, C. A., Meitinger, T., Milaneschi, Y., Nauck, M., Nelson, C. P., O’Connell, J. R., Palmer, N. D., Pereira, A. C., Perls, T., Peters, A., Polašek, O., Raitakari, O. T., Rice, K., Rice, T. K., Rich, S. S., Sabanayagam, C., Schreiner, P. J., Shu, X. O., Sidney, S., Sims, M., Smith, J. A., Starr, J. M., Strauch, K., Tai, E. S., Taylor, K. D., Tsai, M. Y., Uitterlinden, A. G., van Heemst, D., Waldenberger, M., Wang, Y. X., Wei, W. B., Wilson, G., Xuan, D., Yao, J., Yu, C., Yuan, J. M., Zhao, W., Becker, D. M., Bonnefond, A., Bowden, D. W., Cooper, R. S., Deary, I. J., Divers, J., Esko, T., Franks, P. W., Froguel, P., Gieger, C., Jonas, J. B., Kato, N., Lakka, T. A., Leander, K., Lehtimäki, T., Magnusson, P. K. E., North, K. E., Ntalla, I., Penninx, B., Samani, N. J., Snieder, H., Spedicati, B., van der Harst, P., Völzke, H., Wagenknecht, L. E., Weir, D. R., Wojczynski, M. K., Wu, T., Zheng, W., Zhu, X., Bouchard, C., Chasman, D. I., Evans, M. K., Fox, E. R., Gudnason, V., Hayward, C., Horta, B. L., Kardia, S. L. R., Krieger, J. E., Mook-Kanamori, D. O., Peyser, P. A., Province, M. M., Psaty, B. M., Rudan, I., Sim, X., Smith, B. H., van Dam, R. M., van Duijn, C. M., Wong, T. Y., Arnett, D. K., Rao, D. C., Gauderman, J., Liu, C. T., Morrison, A. C., Rotter, J. I. & Fornage, M., 2023, In: Frontiers in Genetics. 14, 16 p., 1235337.

    Research output: Contribution to journal › Journal article › Research › peer-review

  95. Published

    Butyrate and hexanoate-enriched triglycerides increase postprandrial systemic butyrate and hexanoate in men with overweight/obesity: A double-blind placebo-controlled randomized crossover trial

    van Deuren, T., Smolders, L., Hartog, A., Bouwman, F. G., Holst, Jens Juul, Venema, K., Blaak, E. E. & Canfora, E. E., 2023, In: Frontiers in Nutrition. 9, 19 p., 1066950.

    Research output: Contribution to journal › Journal article › Research › peer-review

  96. Published

    Genetic insights into resting heart rate and its role in cardiovascular disease

    van de Vegte, Y. J., Eppinga, R. N., van der Ende, M. Y., Hagemeijer, Y. P., Mahendran, Y., Salfati, E., Smith, A. V., Tan, V. Y., Arking, D. E., Ntalla, I., Appel, E. V., Schurmann, C., Brody, J. A., Rueedi, R., Polasek, O., Sveinbjornsson, G., Lecoeur, C., Ladenvall, C., Zhao, J. H., Isaacs, A. & 31 others, Wang, L., Luan, J., Hwang, S. J., Mononen, N., Auro, K., Jackson, A. U., Bielak, L. F., Zeng, L., Shah, N., Nethander, M., Campbell, A., Rankinen, T., Pechlivanis, S., Qi, L., Zhao, W., Rizzi, F., Tanaka, T., Robino, A., Cocca, M., Lange, L., Müller-Nurasyid, M., Roselli, C., Zhang, W., Kleber, M. E., Witte, D. R., Linneberg, Allan René, Lind, L., Hansen, Torben, Grarup, Niels, Loos, Ruth & DCCT/EDIC Research Group, D. R. G., 2023, In: Nature Communications. 14, 4646.

    Research output: Contribution to journal › Journal article › Research › peer-review

  97. 2024
  98. Published

    Searching for information about stem cells online in an age of artificial intelligence: How should the stem cell community respond?

    Hoeyer, Klaus, Couturier, A., Barawi, K., Drew, C., Grundtvig, Anders, Lane, E., Munk, A. K., Whiteley, Louise & Munsie, M., 2024, In: Stem Cell Reports. 19, 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  99. Published

    Understanding risk and causal mechanisms for developing obesity in infants and young children: A National Institutes of Health workshop

    Aagaard, K. M., Barkin, S. L., Burant, C. F., Carnell, S., Demerath, E., Donovan, S. M., Eneli, I., Francis, L. A., Gilbert-Diamond, D., Hivert, M. F., LeBourgeois, M. K., Loos, R. J. F., Lumeng, J. C., Miller, A. L., Okely, A. D., Osganian, S. K., Ramirez, A. G., Trasande, L., Van Horn, L. V., Wake, M. & 2 others, Wright, R. J. & Yanovski, S. Z., 2024, In: Obesity Reviews. 25, 4, 21 p., e13690.

    Research output: Contribution to journal › Review › Research › peer-review

  100. Published

    Identification of novel homozygous variants in FOXE3 and AP4M1 underlying congenital syndromic anophthalmia and microphthalmia

    Akbar, W., Ullah, A., Haider, N., Suleman, Sufyan, Khan, F. U., Shah, A. A., Sikandar, M. A., Basit, S. & Ahmad, W., 2024, In: Journal of Gene Medicine. 26, 1, 10 p., e3601.

    Research output: Contribution to journal › Journal article › Research › peer-review

  101. Published

    100 ancient genomes show repeated population turnovers in Neolithic Denmark

    Allentoft, M. E., Sikora, M., Fischer, A., Sjögren, K-G., Ingason, A., Macleod, R., Rosengren, A., Schulz Paulsson, B., Jørkov, M. L. S., Novosolov, M., Stenderup, J., Price, T. D., Mortensen, M. F., Nielsen, A. B., Hede, M. U., Sørensen, L., Nielsen, P. O., Rasmussen, P., Jensen, T. Z. T., Refoyo-Martínez, A. & 48 others, Irving-Pease, Evan, Barrie, William Felix Sinclair, Pearson, A., Sousa da Mota, B., Demeter, Fabrice, Henriksen, Rasmus Henrik Amund, Vimala, Tharsika, McColl, Hugh, Vaughn, A., Vinner, Lasse, Renaud, Gabriel, Stern, A., Johannsen, N. N., Ramsøe, Abigail Daisy, Schork, A. J., Ruter, Anthony Henry, Gotfredsen, Anne Birgitte, Nielsen, B. H., Petersen, Erik Brinch, Kannegaard, E., Hansen, J., Pedersen, K. B., Pedersen, L., Klassen, L., Meldgaard, Morten, Johansen, M., Uldum, O. C., Lotz, P., Lysdahl, P., Bangsgaard, Pernille, Petersen, P. V., Maring, R., Iversen, Rune, Wåhlin, S., Sørensen, S. A., Andersen, S. H., Jørgensen, T., Lynnerup, Niels, Lawson, D. J., Rasmussen, Simon, Korneliussen, Thorfinn Sand, Kjær, Kurt H., Durbin, R., Nielsen, Rasmus, Delaneau, O., Werge, Thomas, Kristiansen, Kristian & Willerslev, Eske, 2024, In: Nature. 625, 7994, p. 329-337 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  102. Published

    Population genomics of post-glacial western Eurasia

    Allentoft, M. E., Sikora, M., Refoyo-Martínez, A., Irving-Pease, E. K., Fischer, A., Barrie, W., Ingason, A., Stenderup, J., Sjögren, K-G., Pearson, A., da Mota, B. S., Paulsson, B. S., Halgren, A., Macleod, R., Jørkov, M. L. S., Demeter, F., Sørensen, L., Nielsen, P. O., Henriksen, R. A., Vimala, T. & 144 others, McColl, Hugh, Margaryan, Ashot, Ilardo, M., Vaughn, A., Mortensen, M. F., Nielsen, A. B., Hede, M. U., Johannsen, N. N., Rasmussen, P., Vinner, Lasse, Renaud, Gabriel, Stern, A., Jensen, Theis Zetner Trolle, Scorrano, Gabriele, Schroeder, Hannes, Lysdahl, P., Ramsøe, Abigail Daisy, Skorobogatov, A., Schork, A. J., Rosengren, A., Ruter, Anthony Henry, Outram, A., Timoshenko, A. A., Buzhilova, A., Coppa, A., Zubova, A., Silva, A. M., Hansen, Anders Johannes, Gromov, A., Logvin, A., Gotfredsen, Anne Birgitte, Nielsen, B. H., González-Rabanal, B., Lalueza-Fox, C., McKenzie, C. J., Gaunitz, Charleen, Blasco, C., Liesau, C., Martinez-Labarga, C., Pozdnyakov, D. V., Cuenca-Solana, D., Lordkipanidze, D. O., En’shin, D., Salazar-García, D. C., Price, T. D., Borić, D., Kostyleva, E., Veselovskaya, E. V., Usmanova, E. R., Cappellini, Enrico, Petersen, Erik Brinch, Kannegaard, E., Radina, F., Yediay, Fulya Eylem, Duday, H., Gutiérrez-Zugasti, I., Merts, I., Potekhina, I., Shevnina, I., Altinkaya, Isin, Guilaine, J., Hansen, J., Tortosa, J. E. A., Zilhão, J., Vega, J., Pedersen, K. B., Tunia, K., Zhao, Lei, Mylnikova, L. N., Larsson, L., Metz, L., Yepiskoposyan, L., Pedersen, L., Sarti, L., Orlando, L., Slimak, L., Klassen, L., Blank, M., González-Morales, M., Silvestrini, M., Vretemark, M., Nesterova, M. S., Rykun, M., Rolfo, M. F., Szmyt, M., Przybyła, M., Calattini, M., Sablin, M., Dobisíková, M., Meldgaard, Morten, Johansen, M., Berezina, N., Card, N., Saveliev, N. A., Poshekhonova, O., Rickards, O., Lozovskaya, O. V., Gábor, O., Uldum, O. C., Aurino, P., Kosintsev, P., Courtaud, P., Ríos, P., Mortensen, P., Lotz, P., Persson, P., Bangsgaard, Pernille, de Barros Damgaard, P., Vang Petersen, P., Martinez, P. P., Włodarczak, P., Smolyaninov, R. V., Maring, R., Menduiña, R., Badalyan, R., Iversen, Rune, Turin, R., Vasilyev, S., Wåhlin, S., Borutskaya, S., Skochina, S., Sørensen, S. A., Andersen, S. H., Jørgensen, T., Serikov, Y. B., Molodin, V. I., Smrcka, V., Merts, V., Appadurai, V., Moiseyev, V., Magnusson, Y., Kjær, Kurt H., Lynnerup, Niels, Lawson, D. J., Sudmant, P. H., Rasmussen, Simon, Korneliussen, Thorfinn Sand, Durbin, R., Nielsen, Rasmus, Delaneau, O., Werge, Thomas, Racimo, Fernando, Kristiansen, Kristian & Willerslev, Eske, 2024, In: Nature. 625, 7994, p. 301-311

    Research output: Contribution to journal › Journal article › Research › peer-review

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