- 2012
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Effects of short-term high-fat overfeeding on genome-wide DNA methylation in the skeletal muscle of healthy young men
Jacobsen, S. C., Brøns, C., Bork-Jensen, J., Ribel-Madsen, R., Yang, B., Lara, E., Hall, E., Calvanese, V., Nilsson, E., Jørgensen, S. W., Mandrup, S., Ling, C., Fernandez, A. F., Fraga, M. F., Poulsen, P. & Vaag, Allan, 2012, In: Diabetologia. 55, 12, p. 3341-3349 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Changes in Gastrointestinal Hormone Responses, Insulin Sensitivity, and Beta-Cell Function Within 2 Weeks After Gastric Bypass in Non-diabetic Subjects
Jacobsen, S. H., Olesen, S. C., Dirksen, C., Jørgensen, N. B., Bojsen-Møller, K. N., Kielgast, U., Worm, Dorte, Almdal, Thomas Peter, Naver, L. S., Hvolris, L. E., Rehfeld, Jens Frederik, Wulff, B. S., Clausen, T. R., Hansen, D. L., Holst, Jens Juul & Madsbad, Sten, 2012, In: Obesity Surgery. 22, 7, p. 1084-96 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Enteral bile acid treatment improves parenteral nutrition-related liver disease and intestinal mucosal atrophy in neonatal pigs
Jain, A. K., Stoll, B., Burrin, D. G., Holst, Jens Juul & Moore, D. D., 2012, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 302, 2, p. G218-24Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fish consumption does not prevent increase in waist circumference in European women and men
Jakobsen, M. U., Due, K. M., Dethlefsen, C., Halkjaer, J., Holst, C., Forouhi, N. G., Tjønneland, A., Boeing, H., Buijsse, B., Palli, D., Masala, G., Du, H., van der A, D. L., Wareham, N. J., Feskens, E. J. M., Sørensen, Thorkild I.A. & Overvad, K., 2012, In: British Journal of Nutrition. 108, 5, p. 924-31 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Steroid-induced insulin resistance and impaired glucose tolerance are both associated with a progressive decline of incretin effect in first-degree relatives of patients with type 2 diabetes
Jensen, D. H., Aaboe, K., Henriksen, J. E., Vølund, A., Holst, Jens Juul, Madsbad, Sten & Krarup, T., 2012, In: Diabetologia. 55, 5, p. 1406-16 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An effort to use human-based exome capture methods to analyze chimpanzee and macaque exomes
Jin, X., He, M., Ferguson, B., Meng, Y., Ouyang, L., Ren, J., Mailund, T., Sun, F., Sun, L., Shen, J., Zhuo, M., Song, L., Wang, J., Ling, F., Zhu, Y., Hvilsom, C., Siegismund, H. R., Liu, X., Gong, Z., Ji, F. & 15 others, , 2012, In: P L o S One. 7, 7, 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of a common variant of the PCSK2 gene on reduced insulin secretion
Jonsson, Anna Elisabet, Isomaa, B., Tuomi, T., Eriksson, J. G., Groop, L. & Lyssenko, V., Dec 2012, In: Diabetologia. 55, 12, p. 3245-51 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Acute and long-term effects of Roux-en-Y gastric bypass on glucose metabolism in subjects with Type 2 diabetes and normal glucose tolerance
Jørgensen, N. B., Jacobsen, S. H., Dirksen, C., Bojsen-Møller, K. N., Naver, L., Hvolris, L., Clausen, T. R., Wulff, B. S., Worm, Dorte, Lindqvist Hansen, D., Madsbad, Sten & Holst, Jens Juul, 2012, In: American Journal of Physiology: Endocrinology and Metabolism. 303, 1, p. E122-31Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Systems Genetics Experimental Design and Analyses to Detect Causal Variants and Gene Regulatory Networks for Childhood Obesity in Denmark and India
BioChild consortium, B. C., 2012.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
- Published
Molecular mechanisms of lipoapoptosis and metformin protection in GLP-1 secreting cells
Kappe, C., Holst, Jens Juul, Zhang, Q. & Sjöholm, A., 12 Oct 2012, In: Biochemical and Biophysical Research Communications. 427, 1, p. 91-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Low-grade inflammation in young adults exposed to intrauterine hyperglycemia
Kelstrup, L., Clausen, Tine Dalsgaard, Mathiesen, Elisabeth, Hansen, Torben & Damm, Peter, 2012, In: Diabetes Research and Clinical Practice. 97, 2, p. 322-330 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exogenous glucagon-like peptide-2 (GLP-2) prevents chemotherapy-induced mucositis in rat small intestine
Kissow, Hannelouise, Viby, N., Hartmann, Bolette, Holst, Jens Juul, Timm, M., Thim, L. & Poulsen, Steen Seier, 2012, In: Cancer Chemotherapy and Pharmacology. Supplement. 70, 1, p. 39-48 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-1 (GLP-1) receptor agonism or DPP-4 inhibition does not accelerate neoplasia in carcinogen treated mice
Kissow, Hannelouise, Hartmann, Bolette, Holst, Jens Juul, Viby, N., Gasbjerg, Lærke Smidt, Rosenkilde, Mette, Hare, K. J. & Poulsen, Steen Seier, 10 Nov 2012, In: Regulatory Peptides. 179, 1-3, p. 91-100 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
- Published
Impaired incretin effect and fasting hyperglucagonaemia characterizing type 2 diabetic subjects are early signs of dysmetabolism in obesity
Knop, Filip Krag, Aaboe, K., Vilsbøll, Tina, Vølund, A., Holst, Jens Juul, Krarup, T. & Madsbad, Sten, 2012, In: Diabetes, Obesity and Metabolism. 14, 6, p. 500-510 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Maternal dietary glycaemic load during pregnancy and gestational weight gain, birth weight and postpartum weight retention: a study within the Danish National Birth Cohort
Knudsen, V. K., Heitmann, B. L., Halldorsson, T. I., Sørensen, Thorkild I.A. & Olsen, S. F., 2012, In: British Journal of Nutrition. p. 1-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The PNPLA3 rs738409 G-allele associates with reduced fasting serum triglyceride and serum cholesterol in Danes with impaired glucose regulation
Krarup, N. T., Grarup, Niels, Banasik, Karina, Friedrichsen, M., Færch, K., Sandholt, C. H., Jørgensen, T., Poulsen, P., Witte, D. R., Vaag, Allan, Sørensen, Thorkild I.A., Pedersen, Oluf Borbye & Hansen, Torben, 2012, In: P L o S One. 7, 7, 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Analyses of single nucleotide polymorphisms in selected nutrient-sensitive genes in weight-regain prevention: the DIOGENES study
Larsen, L. H., Ängquist, Lars, Vimaleswaran, K. S., Hager, J., Viguerie, N., Loos, Ruth, Handjieva-Darlenska, T., Jebb, S. A., Kunesova, M., Larsen, T. M., Martinez, J. A., Papadaki, A., Pfeiffer, A. F. H., van Baak, M. A., Sørensen, Thorkild I.A., Holst, C., Langin, D., Astrup, A. & Saris, W. H. M., 2012, In: American Journal of Clinical Nutrition. 95, 5, p. 1254-1260 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Multilocus sequence typing of total-genome-sequenced bacteria
Larsen, Mette Vang, Cosentino, S., Rasmussen, Simon, Friis, Carsten, Hasman, H., Marvig, R. L., Jelsbak, L., Sicheritz-Pontén, T., Ussery, D. W., Aarestrup, F. M. & Lund, O., Apr 2012, In: Journal of Clinical Microbiology. 50, 4, p. 1355-61 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
snpTree--a web-server to identify and construct SNP trees from whole genome sequence data
Leekitcharoenphon, P., Kaas, R. S., Thomsen, M. C. F., Friis, Carsten, Rasmussen, Simon & Aarestrup, F. M., 2012, In: BMC Genomics. 13 Suppl 7, p. S6Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bereavement in early life and later childhood overweight
Li, J., Olsen, J., Vestergaard, M., Obel, C., Baker, J. L. & Sørensen, Thorkild I.A., 2012, In: Obesity Facts. 5, 6, p. 881-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Single-cell sequencing analysis characterizes common and cell-lineage-specific mutations in a muscle-invasive bladder cancer
Li, Y., Xu, X., Song, L., Hou, Y., Li, Z., Tsang, S., Li, F., Im, K., Wu, K., Wu, H., Ye, X., Li, G., Wang, L., Zhang, B., Liang, J., Xie, W., Wu, R., Jiang, H., Liu, X., Yu, C. & 20 others, , 2012, In: GigaScience. 1, 12, 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Randomised controlled trial of colostrum to improve intestinal function in patients with short bowel syndrome
Lund, P., Sangild, Per Torp, Aunsholt, L., Hartmann, Bolette, Holst, Jens Juul, Mortensen, J., Mortensen, P. B. & Jeppesen, P. B., 2012, In: European Journal of Clinical Nutrition. 66, 9, p. 1059-1065 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Validation of a multi-marker model for the prediction of incident type 2 diabetes mellitus: Combined results of the Inter99 and Botnia studies
Lyssenko, V., Jørgensen, T., Gerwien, R. W., Hansen, Torben, Rowe, M. W., McKenna, M. P., Kolberg, J., Pedersen, Oluf Borbye, Borch-Johnsen, K. & Groop, L., Jan 2012, In: Diabetes and Vascular Disease Research. 9, 1Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Intrinsic differences in adipocyte precursor cells from different white fat depots
Macotela, Y., Emanuelli, Brice, Mori, M. A., Gesta, S., Schulz, T. J., Tseng, Y. & Kahn, C. R., Jul 2012, In: Diabetes. 61, 7, p. 1691-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Incretin hormones in patients with type 2 diabetes are increased by diet-oil, a pro-drug for the GPR 119 receptor agonist, 2-oleoyl-glycerol
Mandoe, M. J., Hansen, K. B., Knop, Filip Krag, Holst, Jens Juul & Hansen, Harald S., Oct 2012, In: Diabetologia. 55, p. S340-S340Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Leg length, sitting height and postmenopausal breast cancer risk
Mellemkjær, L., Christensen, J., Frederiksen, K., Baker, J. L., Olsen, A., Sørensen, Thorkild I.A. & Tjønneland, A., 2012, In: B J C. 107, 1, p. 165-8 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Assessment of metagenomic assembly using simulated next generation sequencing data
Mende, D. R., Waller, A. S., Sunagawa, S., Järvelin, A. I., Chan, M. M., Arumugam, Mani, Raes, J. & Bork, P., 2012, In: P L o S One. 7, 2, p. e31386Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structural and functional development of small intestine in intrauterine growth retarded porcine offspring born to gilts fed diets with differing protein ratios throughout pregnancy
Mickiewicz, M., Zabielski, R., Grenier, B., Le Normand, L., Savary, G., Holst, Jens Juul, Oswald, I. P., Metges, C. C. & Guilloteau, P., 2012, In: Journal of Physiology and Pharmacology. 63, 3, p. 225-39 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Novel synthetic route to the C-nucleoside, 2-deoxy benzamide riboside
Midtkandal, R. R., Redpath, P., Trammell, Sam, MacDonald, S. J. F., Brenner, C. & Migaud, M. E., 15 Aug 2012, In: Bioorganic and Medicinal Chemistry Letters. 22, 16, p. 5204-5207 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Modulation of constitutive activity and signaling bias of the ghrelin receptor by conformational constraint in the second extracellular loop
Mokrosinski, J., Frimurer, Thomas Michael, Sivertsen, B., Schwartz, Thue W. & Holst, Birgitte, Sep 2012, In: Journal of Biological Chemistry. 287, p. 33488-33502 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes
Morris, A. P., Voight, B. F., Teslovich, T. M., Ferreira, T., Segrè, A. V., Steinthorsdottir, V., Strawbridge, R. J., Khan, A. H., Grallert, H., Mahajan, A., Prokopenko, I., Kang, H. M., Dina, C., Esko, T., Fraser, R. M., Kanoni, S., Kumar, A., Lagou, V., Langenberg, C., Luan, J. & 31 others, , Sep 2012, In: Nature Genetics. 44, 9, p. 981-90 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of different fractions of whey protein on postprandial lipid and hormone responses in type 2 diabetes
Mortensen, L. S., Holmer-Jensen, J., Hartvigsen, M., Jensen, V. K., Astrup, A., Vrese, M. D., Holst, Jens Juul, Thomsen, C. H. P. & Hermansen, K., 2012, In: European Journal of Clinical Nutrition. 66, 7, p. 799-805 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rational design of conformationally constrained cyclopentapeptide antagonists for C-x-C chemokine receptor 4 (CXCR4)
Mungalpara, J., Thiele, S., Eriksen, Ø., Eksteen, J., Rosenkilde, Mette & Våbenø, J., 9 Oct 2012, In: Journal of Medicinal Chemistry. 55, 22, p. 10287-10291 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mechanisms for the antihyperglycemic effect of sitagliptin in patients with type 2 diabetes
Muscelli, E., Casolaro, A., Gastaldelli, A., Mari, A., Seghieri, G., Astiarraga, B., Chen, Y., Alba, M., Holst, Jens Juul & Ferrannini, E., Aug 2012, In: Journal of Clinical Endocrinology and Metabolism. 97, 8, p. 2818-26 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prolonged successful therapy for hyperinsulinaemic hypoglycaemia after gastric bypass: the pathophysiological role of GLP1 and its response to a somatostatin analogue
Myint, K. S., Greenfield, J. R., Farooqi, I. S., Henning, E., Holst, Jens Juul & Finer, N., 2012, In: European Journal of Endocrinology. 166, 5, p. 951-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of 2weeks lower limb immobilization and two separate rehabilitation regimens on gastrocnemius muscle protein turnover signaling and normalization genes
Nedergaard, A., Jespersen, J. G., Pingel, Jessica, Christensen, B., Sroczynski, N., Langberg, Henning, Kjaer, M. & Schjerling, Peter, 2012, In: BMC Research Notes.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Satiety scores and satiety hormone response after sucrose-sweetened soft drink compared with isocaloric semi-skimmed milk and with non-caloric soft drink: a controlled trial
Nielsen, M. M., Sparre, A. B., Holst, Jens Juul, Fenger-Grøn, M., Pedersen, S. B., Astrup, A. & Richelsen, B., 2012, In: European Journal of Clinical Nutrition. 66, 4, p. 523-529 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Metabolic effects of short-term GLP-1 treatment in insulin resistant heart failure patients
Nielsen, R., Wiggers, H., Halbirk, M., Bøtker, H., Holst, Jens Juul, Schmitz, O., Frandsen, E. R., Nielsen, S., Møller, N. & Nørrelund, H., 2012, In: Experimental and Clinical Endocrinology and Diabetes. 120, 5, p. 266-72 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
MicroRNA expression profiling of carcinoma in situ cells of the testis
Novotny, G. W., Belling, K. C., Bramsen, J. B., Nielsen, J. E., Bork-Jensen, J., Almstrup, Kristian, Sonne, Si Brask, Kjems, J., Rajpert-De Meyts, E. & Leffers, H., 2012, In: Endocrine - Related Cancer. 19, p. 365-379 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transcriptional and translational regulation of cytokine signaling in inflammatory ß-cell dysfunction and apoptosis
Novotny, G. W., Lundh, M., Backe, M. B., Christensen, D. P., Hansen, J. B., Dahllöf, M. S., Pallesen, E. & Mandrup-Poulsen, Thomas, 2012, In: Archives of Biochemistry and Biophysics. 528, 2, p. 171-84Research output: Contribution to journal › Review › Research › peer-review
- Published
Metformin stimulates FGF21 expression in primary hepatocytes
Nygaard, E. B., Vienberg, S. G., Ørskov, Cathrine, Hansen, Harald S. & Andersen, B., 2012, In: Experimental Diabetes Research. 2012, p. 465282 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Treatment of adult short bowel syndrome patients with teduglutide
Nørholk, L. M., Holst, Jens Juul & Jeppesen, Palle Bekker, 2012, In: Expert Opinion on Pharmacotherapy. 13, 2, p. 235-43 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The incretin effect in patients with maturity onset diabetes of the young
Ostoft, S. H., Bagger, J. I., Hansen, T., Pedersen, O., Holst, Jens Juul, Knop, Filip Krag & Vilsboll, T., 2012, In: Diabetologia. 55, p. S144-S144Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A genome-wide association search for type 2 diabetes genes in African Americans
Palmer, N. D., McDonough, C. W., Hicks, P. J., Roh, B. H., Wing, M. R., An, S. S., Hester, J. M., Cooke, J. N., Bostrom, M. A., Rudock, M. E., Talbert, M. E., Lewis, J. P., Ferrara, A., Lu, L., Ziegler, J. T., Sale, M. M., Divers, J., Shriner, D., Adeyemo, A., Rotimi, C. N. & 31 others, , 2012, In: P L o S One. 7, 1, p. e29202Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cross-talk between insulin and Wnt signaling in preadipocytes: role of Wnt co-receptor low density lipoprotein receptor-related protein-5 (LRP5)
Palsgaard, J., Emanuelli, Brice, Winnay, J. N., Sumara, G., Karsenty, G. & Kahn, C. R., 6 Apr 2012, In: The Journal of Biological Chemistry. 287, 15, p. 12016-26 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Improving membrane binding as a design strategy for amphipathic peptide hormones: 2-helix variants of PYY3-36
Pedersen, S. L., Bhatia, V. K., Jurt, S., Paulsson, J. F., Pedersen, M. H., Jørgensen, R., Holst, Birgitte, Stamou, Dimitrios, Vrang, N., Zerbe, O. & Jensen, Knud Jørgen, 2012, In: Journal of Peptide Science. 18, 9, p. 579-587 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Leptin-induced mTOR activation defines a specific molecular and transcriptional signature controlling CD4+ effector T cell responses
Procaccini, C., De Rosa, V., Galgani, M., Carbone, F., Cassano, S., Greco, D., Qian, K., Auvinen, P., Calì, G., Stallone, G., Formisano, L., La Cava, A. & Matarese, G., 15 Sep 2012, In: Journal of Immunology. 189, 6, p. 2941-53 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Re-analysis of bipolar disorder and schizophrenia gene expression complements the Kraepelinian dichotomy
Qian, K., Di Lieto, A., Corander, J., Auvinen, P. & Greco, D., 2012, In: Advances in Experimental Medicine and Biology. 736, p. 563-77 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
miRSeqNovel: an R based workflow for analyzing miRNA sequencing data
Qian, K., Auvinen, E., Greco, D. & Auvinen, P., Oct 2012, In: Molecular and Cellular Probes. 26, 5, p. 208-11 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A metagenome-wide association study of gut microbiota in type 2 diabetes
Qin, J., Li, Y., Cai, Z., Li, S., Zhu, J., Zhang, F., Liang, S., Zhang, W., Guan, Y., Shen, D., Peng, Y., Zhang, D., Jie, Z., Wu, W., Qin, Y., Xue, W., Li, J., Han, L., Lu, D., Wu, P. & 36 others, , 2012, In: Nature. 490, 7418, p. 55-60 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Linagliptin, a selective DPP-4 inhibitor, inhibits DPP-4, increases incretin levels, lowers glucagon, and improves glycaemic control in patients with Type 2 diabetes.
Rauch, T., Graefe-Mody, U., Deacon, Carolyn F., Ring, A., Holst, Jens Juul, Woerle, H., Dugi, K. & Heise, T., 2012, In: Diabetes Therapy. 3, 1, p. 10Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Linagliptin increases incretin levels, lowers glucagon, and improves glycemic control in type 2 diabetes mellitus
Rauch, T., Graefe-Mody, U., Deacon, Carolyn F., Ring, A., Holst, Jens Juul, Woerle, H., Dugi, K. A. & Heise, T., Nov 2012, In: Diabetes Therapy. 3, 1, p. 10Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide analysis of DNA methylation differences in muscle and fat from monozygotic twins discordant for type 2 diabetes
Ribel-Madsen, R., Fraga, M. F., Jacobsen, S., Bork-Jensen, J., Lara, E., Calvanese, V., Fernandez, A. F., Friedrichsen, M., Vind, B. F., Højlund, K., Beck-Nielsen, H., Esteller, M., Vaag, Allan & Poulsen, P., 2012, In: P L o S One. 7, 12, p. e51302Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Receptor oligomerization in family B1 of G-protein-coupled receptors: focus on BRET investigations and the link between GPCR oligomerization and binding cooperativity
Roed, S. N., Ørgaard, A., Jørgensen, R. & De Meyts, P., 2012, In: Frontiers in Endocrinology. 3, p. 62 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impaired crosstalk between pulsatile insulin and glucagon secretion in prediabetic individuals
Rohrer, S., Menge, B. A., Grüber, L., Deacon, Carolyn F., Schmidt, W. E., Veldhuis, J. D., Holst, Jens Juul & Meier, J. J., 2012, In: Journal of Clinical Endocrinology and Metabolism. 97, 5, p. E791-E795Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reduced insulin exocytosis in human pancreatic β-cells with gene variants linked to type 2 diabetes
Rosengren, A. H., Braun, M., Mahdi, T., Andersson, S. A., Travers, M. E., Shigeto, M., Zhang, E., Almgren, P., Ladenvall, C., Axelsson, A. S., Edlund, A., Pedersen, M. G., Jonsson, A. E., Ramracheya, R., Tang, Y., Walker, J. N., Barrett, A., Johnson, P. R. V., Lyssenko, V., McCarthy, M. I. & 6 others, , Jul 2012, In: Diabetes. 61, 7, p. 1726-33 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The insulinogenic effect of whey protein is partially mediated by a direct effect of amino acids and GIP on β-cells
Salehi, A., Gunnerud, U., Muhammed, S. J., Ostman, E., Holst, Jens Juul, Björck, I. & Rorsman, P., 2012, In: Nutrition & Metabolism. 9, 1, p. 48Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies
Sarwar, N., Butterworth, A. S., Freitag, D. F., Gregson, J., Willeit, P., Gorman, D. N., Gao, P., Saleheen, D., Rendon, A., Nelson, C. P., Braund, P. S., Hall, A. S., Chasman, D. I., Tybjærg-Hansen, A., Chambers, J. C., Benjamin, E. J., Franks, P. W., Clarke, R., Wilde, A. A. M., Trip, M. D. & 31 others, , 31 Mar 2012, In: Lancet. 379, 9822, p. 1205-13 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
SDCCAG8 obesity alleles and reduced weight loss after a lifestyle intervention in overweight children and adolescents
Scherag, A., Kleber, M., Boes, T., Kolbe, A., Ruth, A., Grallert, H., Illig, T., Heid, I. M., Toschke, A. M., Grau, K., Sørensen, Thorkild I.A., Hebebrand, J., Hinney, A., Reinehr, T. & NUGENOB Consortium, N. C., 2012, In: Obesity. 20, 2, p. 466-70 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of intravenous infusions of PYY3-36 and GLP-1, as monoinfusion and in combination, on ad libitum energy intake in healthy obese subjects
Schmidt, J. B., Gregersen, N. T., Pedersen, S. D., Holst, Jens Juul, Schwartz, Thue W., Astrup, A. & Sjödin, Anders Mikael, 10 Aug 2012, In: Regulatory Peptides. 177, Supplement, p. S32 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Roux-en-Y gastric bypass surgery does not preserve energy expenditure in humans
Schmidt, J. B., Gunvald, L. E., Gregersen, N. T., Pedersen, S. D., Holst, Jens Juul, Hansen, D. L., Worm, Dorte, Madsbad, Sten, Astrup, A. & Sjödin, Anders Mikael, 2012, In: Regulatory Peptides. 177, suppl.1, p. S32 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Effects of everyday life events on glucose, insulin, and glucagon dynamics in continuous subcutaneous insulin infusion-treated type 1 diabetes: collection of clinical data for glucose modeling
Schmidt, S. D., Finan, D. A., Duun-Henriksen, A. K., Jørgensen, J. B., Madsen, H., Bengtsson, H., Holst, Jens Juul, Madsbad, S. & Nørgaard, K., 2012, In: Diabetes Technology & Therapeutics. 14, 3, p. 210-217 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Maternal Recreational Exercise during Pregnancy in relation to Children's BMI at 7 Years of Age
Schou Andersen, C., Juhl, M., Gamborg, M., Sørensen, Thorkild I.A. & Nohr, E. A., 2012, In: International Journal of Pediatrics. 2012, p. 920583Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways
Diabetes Genetics Replication and Meta-analysis (DIAGRAM) Consortium, D. G. R. A. M. (. C., Sep 2012, In: Nature Genetics. 44, 9, p. 991-1005 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
No interactions between previously associated 2-hour glucose gene variants and physical activity or BMI on 2-hour glucose levels
Scott, R. A., Chu, A. Y., Grarup, N., Manning, A. K., Hivert, M-F., Shungin, D., Tönjes, A., Yesupriya, A., Barnes, D., Bouatia-Naji, N., Glazer, N. L., Jackson, A. U., Kutalik, Z., Lagou, V., Marek, D., Rasmussen-Torvik, L. J., Stringham, H. M., Tanaka, T., Aadahl, M., Arking, D. E. & 87 others, , 2012, In: Diabetes. 61, 5, p. 1291-6 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The combination of colesevelam with sitagliptin enhances glycemic control in diabetic ZDF rat model
Shang, Q., Liu, M. K., Saumoy, M., Holst, Jens Juul, Salen, G. & Xu, G., 2012, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 302, 8, p. G815-23Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Analysis of substrate specificity and cyclin Y binding of PCTAIRE-1 kinase
Shehata, S. N., Hunter, R. W., Ohta, E., Peggie, M. W., Lou, H. J., Sicheri, F., Zeqiraj, E., Turk, B. E. & Sakamoto, Kei, 1 Nov 2012, In: Cellular Signalling. 24, 11, p. 2085-2094 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Growth in height in childhood and risk of coronary heart disease in adult men and women
Silventoinen, K., Baker, J. L. & Sørensen, Thorkild I.A., 2012, In: P L o S One. 7, 1, p. e30476Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Muscle mitochondrial metabolism and calcium signaling impairment in patients treated with statins
Sirvent, P., Fabre, O. M. J., Bordenave, S., Hillaire-Buys, D., Raynaud De Mauverger, E., Lacampagne, A. & Mercier, J., 1 Mar 2012, In: Toxicology and Applied Pharmacology. 259, 2, p. 263-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of glucagon-like peptide 1 on cardiovascular risk
Sivertsen, J., Rosenmeier, J., Holst, Jens Juul & Vilsbøll, T., Apr 2012, In: Nature Reviews Cardiology. 9, 4, p. 209-22 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Common variation in oxidative phosphorylation genes is not a major cause of insulin resistance or type 2 diabetes
Snogdal, L. S., Wod, M., Grarup, Niels, Vestmar, M., Sparsø, T. H., Jørgensen, T., Lauritzen, T., Beck-Nielsen, H., Henriksen, J. E., Pedersen, Oluf Borbye, Hansen, Torben & Højlund, K., 2012, In: Diabetologia. 55, 2, p. 340-8 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Examining the effects of hyperglycemia on pancreatic endocrine function in humans: evidence for in vivo glucotoxicity
Solomon, T. P. J., Knudsen, S. H., Karstoft, K., Winding, K., Holst, Jens Juul & Pedersen, Bente Klarlund, Dec 2012, In: Journal of Clinical Endocrinology and Metabolism. 97, 12, p. 4682-91 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Single nucleotide polymorphisms in IL1B and the risk of acute coronary syndrome: a Danish case-cohort study
Stegger, J. G., Schmidt, E. B., Tjønneland, A., Kopp, T. I., Sørensen, Thorkild I.A., Vogel, U. B. & Overvad, K., 2012, In: P L o S One. 7, 6, p. e36829Research output: Contribution to journal › Journal article › Research › peer-review
- Published
TFAP2B influences the effect of dietary fat on weight loss under energy restriction
Stocks, T., Angquist, L., Banasik, K., Harder, M. N., Taylor, M. A., Hager, J., Arner, P., Oppert, J-M., Martinez, J. A., Polak, J., Rousseau, F., Langin, D., Rössner, S., Holst, C., Macdonald, I. A., Kamatani, Y., Pfeiffer, A. F. H., Kunesova, M., Saris, W. H. M., Hansen, T. & 3 others, , 2012, In: P L o S One. 7, 8, p. e43212 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Continuous parenteral and enteral nutrition induces metabolic dysfunction in neonatal pigs
Stoll, B., Puiman, P. J., Cui, L., Chang, X., Benight, N. M., Bauchart-Thevret, C., Hartmann, Bolette, Holst, Jens Juul & Burrin, D. G., Sep 2012, In: Journal of Parenteral and Enteral Nutrition. 36, 5, p. 538-50 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
5'-AMP activated protein kinase is involved in the regulation of myocardial ß-oxidative capacity in mice
Stride, N., Larsen, S., Treebak, Jonas Thue, Hansen, C. N., Hey-Mogensen, M., Speerschneider, T., Jensen, Thomas Elbenhardt, Jeppesen, J., Wojtaszewski, Jørgen F P, Richter, Erik A., Køber, Lars Valeur & Dela, Flemming, 22 Feb 2012, In: Frontiers in Physiology. 3, 7 p., 00033.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A genome-wide association study of monozygotic twin-pairs suggests a locus related to variability of serum high-density lipoprotein cholesterol
Surakka, I., Whitfield, J. B., Perola, M., Visscher, P. M., Montgomery, G. W., Falchi, M., Willemsen, G., de Geus, E. J. C., Magnusson, P. K. E., Christensen, K., Sørensen, T. I. A., Pietiläinen, K. H., Rantanen, T., Silander, K., Widén, E., Muilu, J., Rahman, I., Liljedahl, U., Syvänen, A-C., Palotie, A. & 9 others, , 2012, In: Twin Research and Human Genetics. 15, 6, p. 691-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of a very low calorie diet on insulin sensitivity, beta cell function, insulin clearance, incretin hormone secretion, androgen levels and body composition in obese young women
Svendsen, P. F., Jensen, F. K., Holst, Jens Juul, Haugaard, Steen Bendix, Nilas, L. & Madsbad, Sten, Sep 2012, In: Scandinavian Journal of Clinical & Laboratory Investigation. 72, 5, p. 410-9 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Rab-GTPase-activating protein TBC1D1 regulates skeletal muscle glucose metabolism
Szekeres, F., Chadt, A., Tom, R. Z., Deshmukh, Atul Shahaji, Chibalin, A. V., Björnholm, M., Al-Hasani, H. & Zierath, Juleen R, 15 Aug 2012, In: American Journal of Physiology: Endocrinology and Metabolism. 303, 4, p. E524-33Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A systems genetics approach identifies genes and pathways for type 2 diabetes in human islets
Taneera, J., Lang, S., Sharma, A., Fadista, J., Zhou, Y., Ahlqvist, E., Jonsson, A. E., Lyssenko, V., Vikman, P., Hansson, O., Parikh, H., Korsgren, O., Soni, A., Krus, U., Zhang, E., Jing, X-J., Esguerra, J. L. S., Wollheim, C. B., Salehi, A., Rosengren, A. & 2 others, , 3 Jul 2012, In: Cell Metabolism. 16, 1, p. 122-34 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-2 (GLP-2) increases net amino acid utilization by the portal-drained viscera of ruminating calves
Taylor-Edwards, C. C., Burrin, D. G., Kristensen, N. B., Holst, Jens Juul, McLeod, K. R. & Harmon, D. L., Dec 2012, In: Animal. 6, 12, p. 1985-97 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Modulation in selectivity and allosteric properties of small-molecule ligands for CC-chemokine receptors
Thiele, S., Malmgaard-Clausen, M., Engel-Andreasen, J., Steen, A., Rummel, P. C., Nielsen, M. C., Gloriam, David E., Frimurer, Thomas Michael, Ulven, Trond & Rosenkilde, Mette, 27 Sep 2012, In: Journal of Medicinal Chemistry. 55, 18, p. 8164-77 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic variation in the 15q25 nicotinic acetylcholine receptor gene cluster (CHRNA5-CHRNA3-CHRNB4) interacts with maternal self-reported smoking status during pregnancy to influence birth weight
Tyrrell, J., Huikari, V., Christie, J. T., Cavadino, A., Bakker, R., Brion, M-J. A., Geller, F., Paternoster, L., Myhre, R., Potter, C., Johnson, P. C. D., Ebrahim, S., Feenstra, B., Hartikainen, A-L., Hattersley, A. T., Hofman, A., Kaakinen, M., Lowe, L. P., Magnus, P., McConnachie, A. & 24 others, , 2012, In: Human Molecular Genetics. 21, 24, p. 5344-58 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
PheVI:09 (Phe6.44) as a sliding microswitch in seven-transmembrane (7TM) G protein-coupled receptor activation
Valentin-Hansen, L., Holst, Birgitte, Frimurer, Thomas Michael, Schwartz, Thue W. & Hansen, L. V., 21 Dec 2012, In: Journal of Biological Chemistry. 287, 52, p. 43516-43526 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Insulin resistance after a 72-h fast is associated with impaired AS160 phosphorylation and accumulation of lipid and glycogen in human skeletal muscle
Vendelbo, M., Clasen, B. F. F., Treebak, Jonas Thue, Møller, L., Krusenstjerna-Hafstrøm, T., Madsen, M., Nielsen, Thomas Svava, Stødkilde-Jørgensen, H., Pedersen, S. B., Jørgensen, J. O. L., Goodyear, L. J., Wojtaszewski, Jørgen F P, Møller, N. & Jessen, N., 2012, In: American Journal of Physiology: Endocrinology and Metabolism. 302, 2, p. E190-E200 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Time-Resolved quantitative phosphoproteomics: New insights into angiotensin-(1-7) signaling networks in human endothelial cells
Verano-Braga, T., Schwämmle, V., Sylvester, M., Passos-Silva, D. G., Peluso, A. A. B., Etelvino, G. M., Santos, R. A. S. & Roepstorff, P., 2012, In: Journal of Proteome Research.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Propionate absorbed from the colon acts as gluconeogenic substrate in a strict carnivore, the domestic cat (Felis catus)
Verbrugghe, A., Hesta, M., Daminet, S., Polis, I., Holst, Jens Juul, Buyse, J., Wuyts, B. & Janssens, G. P. J., Dec 2012, In: Journal of Animal Physiology and Animal Nutrition (Online). 96, 6, p. 1054-64 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Adipose-specific deletion of TFAM increases mitochondrial oxidation and protects mice against obesity and insulin resistance
Vernochet, C., Mourier, A., Bezy, O., Macotela, Y., Boucher, J., Rardin, M. J., An, D., Lee, K. Y., Ilkayeva, O. R., Zingaretti, C. M., Emanuelli, Brice, Smyth, G., Cinti, S., Newgard, C. B., Gibson, B. W., Larsson, N. & Kahn, C. R., 5 Dec 2012, In: Cell Metabolism. 16, 6, p. 765-76 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Development of obesity and polycystic ovary syndrome in adolescents
Vilmann, L. S., Thisted, E., Baker, J. L. & Holm, Jens-Christian, 2012, In: Hormone Research in Paediatrics. 78, 5-6, p. 269-78 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Attention in a bayesian framework
Whiteley, Louise & Sahani, M., 14 Jun 2012, In: Frontiers in Human Neuroscience. 6, 100Research output: Contribution to journal › Journal article › Research › peer-review
- Published
No body is as it seems
Whiteley, Louise, 29 Jun 2012, In: Science (New York, N.Y.). 336, 6089, p. 1641 1 p.Research output: Contribution to journal › Literature review › Research
- Published
Resisting the Revelatory Scanner: Critical Engagements with fMRI in Popular Media
Whiteley, Louise, 2012, In: BioSocieties. 7, 3, p. 245-272Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Resequencing 50 accessions of cultivated and wild rice yields markers for identifying agronomically important genes
Xu, X., Liu, X., Ge, S., Jensen, J. D., Hu, F., Li, X., Dong, Y., Gutenkunst, R. N., Fang, L., Huang, L., Li, J., He, W., Zhang, G., Zheng, X., Zhang, F., Li, Y., Yu, C., Kristiansen, K., Zhang, X., Wang, J. & 5 others, , 2012, In: Nature Biotechnology. 30, 1, p. 105-111 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Single-cell exome sequencing reveals single-nucleotide mutation characteristics of a kidney tumor: Cell
Xu, X., Hou, Y., Yin, X., Bao, L., Tang, A., Song, L., Li, F., Tsang, S., Wu, K., Wu, H., He, W., Zeng, L., Xing, M., Wu, R., Jiang, H., Liu, X., Cao, D., Guo, G., Hu, X., Gui, Y. & 19 others, , 2012, In: Cell. 148, 5, p. 886-895 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The human small intestinal microbiota is driven by rapid uptake and conversion of simple carbohydrates
Zoetendal, E. G., Raes, J., van den Bogert, B., Arumugam, Mani, Booijink, C. C. G. M., Troost, F. J., Bork, P., Wels, M., de Vos, W. M. & Kleerebezem, M., 2012, In: I S M E Journal. 6, 7, p. 1415-26 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Chenodeoxycholic acid reduces intestinal permeability in newly weaned piglets
van der Meer, Y., Gerrits, W. J. J., van den Bosch, M., Holst, Jens Juul, Moreto, M., Buurman, W. A., Kulik, W. & van Kempen, T. A. T. G., Dec 2012, In: Journal of Animal Science. 90 Suppl 4, p. 302-4 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2013
- Published
The CTRB1/2 locus affects diabetes susceptibility and treatment via the incretin pathway
't Hart, L. M., Fritsche, A., Nijpels, G., van Leeuwen, N., Donnelly, L. A., Dekker, J. M., Alssema, M., Fadista, J., Carlotti, F., Gjesing, A. P., Palmer, C. N. A., van Haeften, T. W., Herzberg-Schäfer, S. A., Simonis-Bik, A. M. C., Houwing-Duistermaat, J. J., Helmer, Q., Deelen, J., Guigas, B., Hansen, T., Machicao, F. & 14 others, , 14 May 2013, In: Diabetes. 62, 9, p. 3275-3281 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gene x Physical Activity Interactions in Obesity: Combined Analysis of 111,421 Individuals of European Ancestry
Ahmad, S., Rukh, G., Varga, T. V., Ali, A., Kurbasic, A., Shungin, D., Ericson, U., Koivula, R. W., Chu, A. Y., Rose, L. M., Ganna, A., Qi, Q., Stancakova, A., Sandholt, C. H., Elks, C. E., Curhan, G., Jensen, M. K., Tamimi, R. M., Allin, K. H., Jorgensen, T. & 26 others, , Jul 2013, In: PLOS Genetics. 9, 7Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gene × physical activity interactions in obesity: combined analysis of 111,421 individuals of European ancestry
Ahmad, S., Rukh, G., Varga, T. V., Ali, A., Kurbasic, A., Shungin, D., Ericson, U., Koivula, R. W., Chu, A. Y., Rose, L. M., Ganna, A., Qi, Q., Stančáková, A., Sandholt, C. H., Elks, C. E., Curhan, G., Jensen, M. K., Tamimi, R. M., Allin, K. H., Jørgensen, T. & 27 others, , Jul 2013, In: P L o S Genetics (Online). 9, 7, p. e1003607Research output: Contribution to journal › Journal article › Research › peer-review
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Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
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Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets
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The isoenzyme pattern of LDH does not play a physiological role; except perhaps during fast transitions in energy metabolism
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Determinants of plasma levels of proglucagon and the metabolic impact of glucagon receptor signalling: a UK Biobank study
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Targeting postsynaptic glutamate receptor scaffolding proteins PSD-95 and PICK1 for obesity treatment
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mTORC1 controls murine postprandial hepatic glycogen synthesis via Ppp1r3b
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