Novo Nordisk Foundation Center for Basic Metabolic Research

  1. Published

    Characterization of immunoactive pancreastatin in porcine tissues

    Børglum, T. D., Holst, Jens Juul & Fahrenkrug, J., 1991, In: Scand. J. Clin. Lab. Invest.. 51, p. 681-691

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Multi-technique approach for qualitative and quantitative characterization of furazidin degradation kinetics under alkaline conditions

    Bērziņš, Kārlis, Kons, A., Grante, I., Dzabijeva, D., Nakurte, I. & Actiņš, A., 2016, In: Journal of Pharmaceutical and Biomedical Analysis.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Interaction between dietary lipids and gut microbiota regulates hepatic cholesterol metabolism

    Caesar, R., Nygren, H., Orešič, M. & Bäckhed, G. F., Mar 2016, In: Journal of Lipid Research. 57, 3, p. 474-81 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Crosstalk between Gut Microbiota and Dietary Lipids Aggravates WAT Inflammation through TLR Signaling

    Caesar, R., Tremaroli, V., Kovatcheva-Datchary, P., Cani, P. D. & Bäckhed, G. F., 6 Oct 2015, In: Cell Metabolism. 22, 4, p. 658-68 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Chronic erythropoietin treatment improves diet-induced glucose intolerance in rats

    Caillaud, C., Mechta, Mie, Ainge, H., Madsen, A. N., Ruell, P., Mas, E., Bisbal, C., Mercier, J., Twigg, S., Mori, T. A., Simar, D. & Barrès, Romain, 2015, In: Journal of Endocrinology. 225, 2, p. 77-88 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Secretion of glucagon-like peptide-1 in patients with type 2 diabetes mellitus: systematic review and meta-analyses of clinical studies

    Calanna, S., Christensen, M., Holst, Jens Juul, Laferrère, B., Gluud, Lise Lotte, Vilsbøll, Tina & Knop, Filip Krag, May 2013, In: Diabetologia. 56, 5, p. 965-72 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Secretion of glucose-dependent insulinotropic polypeptide in patients with type 2 diabetes: systematic review and meta-analysis of clinical studies

    Calanna, S., Christensen, Mikkel Bring, Holst, Jens Juul, Laferrère, B., Gluud, Lise Lotte, Vilsbøll, T. & Knop, Filip Krag, Oct 2013, In: Diabetes Care. 36, 10, p. 3346-52 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Alcohol intake and its effect on some appetite-regulating hormones in man: influence of gastroprotection with sucralfate

    Calissendorff, J., Gustafsson, T., Holst, Jens Juul, Brismar, K. & Röjdmark, S., 2012, In: Endocrine Research. 37, 3, p. 154-62 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Long-term effects of bariatric surgery on meal disposal and β-cell function in diabetic and nondiabetic patients

    Camastra, S., Muscelli, E., Gastaldelli, A., Holst, Jens Juul, Astiarraga, B., Baldi, S., Nannipieri, M., Ciociaro, D., Anselmino, M., Mari, A. & Ferrannini, E., Nov 2013, In: Diabetes. 62, 11, p. 3709-17 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    A molecular census of arcuate hypothalamus and median eminence cell types

    Campbell, J. N., Macosko, E. Z., Fenselau, H., Pers, Tune H, Lyubetskaya, A., Tenen, D., Goldman, M., Verstegen, A. M. J., Resch, J. M., McCarroll, S. A., Rosen, E. D., Lowell, B. B. & Tsai, L. T., Mar 2017, In: Nature Neuroscience. 20, 3, p. 484-496 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Mechanism by which arylamine N-acetyltransferase 1 ablation causes insulin resistance in mice

    Camporez, J. P., Wang, Y., Faarkrog, K., Chukijrungroat, N., Petersen, K. F. & Shulman, G. I., Dec 2017, In: Proceedings of the National Academy of Sciences of the United States of America. 114, 52, p. E11285-E11292 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Supplementation of Diet With Galacto-oligosaccharides Increases Bifidobacteria, but Not Insulin Sensitivity, in Obese Prediabetic Individuals

    Canfora, E. E., van der Beek, C. M., Hermes, G. D. A., Goossens, G. H., Jocken, J. W. E., Holst, Jens Juul, van Eijk, H. M., Venema, K., Smidt, H., Zoetendal, E. G., Dejong, C. H. C., Lenaerts, K. & Blaak, E. E., Jul 2017, In: Gastroenterology. 153, 1, p. 87-97.e3

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Colonic infusions of short-chain fatty acid mixtures promote energy metabolism in overweight/obese men: a randomized crossover trial

    Canfora, E. E., van der Beek, C. M., Jocken, J. W. E., Goossens, G. H., Holst, Jens Juul, Olde Damink, S. W. M., Lenaerts, K., Dejong, C. H. C. & Blaak, E. E., 24 May 2017, In: Scientific Reports. 7, 12 p., 2360.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Fiber mixture-specific effect on distal colonic fermentation and metabolic health in lean but not in prediabetic men

    Canfora, E. E., Hermes, G. D. A., Mueller, M., Bastings, J., Vaughan, E. E., van den Berg, M. A., Holst, Jens Juul, Venema, K., Zoetendal, E. G. & Blaak, E. E., 2022, In: Gut Microbes. 14, 1

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    2′-fucosyllactose alone or combined with resistant starch increases circulating short-chain fatty acids in lean men and men with prediabetes and obesity

    Canfora, E. E., Vliex, L. M. M., Wang, T., Nauta, A., Bouwman, F. G., Holst, Jens Juul, Venema, K., Zoetendal, E. G. & Blaak, E. E., 2023, In: Frontiers in Nutrition. 10, 13 p., 1200645.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    AMPK regulates energy expenditure by modulating NAD + metabolism and SIRT1 activity

    Cantó, C., Gerhart-Hines, Zach, Feige, J. N., Lagouge, M., Noriega, L., Milne, J. C., Elliott, P. J., Puigserver, P. & Auwerx, J., 23 Apr 2009, In: Nature. 458, 7241, p. 1056-1060 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Interdependence of AMPK and SIRT1 for metabolic adaptation to fasting and exercise in skeletal muscle

    Cantó, C., Jiang, L. Q., Deshmukh, Atul Shahaji, Mataki, C., Coste, A., Lagouge, M., Zierath, Juleen R & Auwerx, J., 3 Mar 2010, In: Cell Metabolism. 11, 3, p. 213-9 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    A short-read multiplex sequencing method for reliable, cost-effective and high-throughput genotyping in large-scale studies: [plus] Erratum

    Cao, H., Wang, Y., Zhang, W., Chai, X., Zhang, X., Chen, S., Yang, F., Zhang, C., Guo, Y., Liu, Y., Tang, Z., Chen, C., Xue, Y., Zhen, H., Xu, Y., Rao, B., Liu, T., Zhao, M., Zhang, W., Li, Y. & 6 others, Zhang, X., Tellier, L. C. A. M., Krogh, Anders, Kristiansen, Karsten, Wang, J. & Li, J., 2013, In: Human Mutation. 34, 12, p. 1715-1720 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    An integrated tool to study MHC region: accurate SNV detection and HLA genes typing in human MHC region using targeted high-throughput sequencing

    Cao, H., Wu, J., Wang, Y., Jiang, H., Zhang, T., Liu, X., Xu, Y., Liang, D., Gao, P., Sun, Y., Gifford, B., D'Ascenzo, M., Liu, X., Tellier, L. C. A. M., Yang, F., Tong, X., Chen, D., Zheng, J., Li, W., Richmond, T. & 3 others, Xu, X., Wang, J. & Li, Y., 2013, In: P L o S One. 8, 7, 9 p., e69388.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Whole exome sequencing of insulinoma reveals recurrent T372R mutations in YY1

    Cao, Y., Gao, Z., Li, L., Jiang, X., Shan, A., Cai, J., Peng, Y., Li, Y., Jiang, X., Huang, X., Wang, J., Wei, Q., Qin, G., Zhao, J., Jin, X., Liu, L., Li, Y., Wang, W., Wang, J. & Ning, G., 2013, In: Nature Communications. 4, 6 p., 2810.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Spinal astroglial cannabinoid receptors control pathological tremor

    Carlsen, Eva Maria Meier, Falk, S., Skupio, U., Robin, L., Zottola, A. C. P., Marsicano, G. & Perrier, Jean-Francois Marie, 2021, In: Nature Neuroscience. 24, p. 658–666 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    A metabolic prosurvival role for PML in breast cancer

    Carracedo, A., Weiss, D., Leliaert, A. K., Bhasin, M., De Boer, V. C. J., Laurent, G., Adams, A. C., Sundvall, M., Song, S. J., Ito, K., Finley, L. S., Egia, A., Libermann, T., Gerhart-Hines, Zach, Puigserver, P., Haigis, M. C., Maratos-Flier, E., Richardson, A. L., Schafer, Z. T. & Pandolfi, P. P., 4 Sep 2012, In: Journal of Clinical Investigation. 122, 9, p. 3088-3100 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Does genetic predisposition to higher fat expandability attenuate the impact of weight gain on cardiometabolic risk?

    Carrasquilla, Germán D., Linneberg, Allan René, Jørgensen, T., Grarup, Niels, Pedersen, Oluf Borbye, Hansen, Torben, Sørensen, Thorkild I.A. & Kilpeläinen, Tuomas O., 2019, In: European Journal of Human Genetics. 27, Suppl. 2, p. 1764 1 p.

    Research output: Contribution to journalConference abstract in journalResearch

  24. Published

    Causality between physical activity, sedentary behavior and obesity: A Mendelian randomization study

    Carrasquilla, Germán D., García Ureña, Mario, Fall, T., Sørensen, Thorkild I.A. & Kilpeläinen, Tuomas O., 2022, In: European Journal of Human Genetics. 30, Supplement 1, p. 536-536 1 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  25. Published

    Postmenopausal hormone therapy and risk of stroke: A pooled analysis of data from population-based cohort studies

    Carrasquilla, Germán D., Frumento, P., Berglund, A., Borgfeldt, C., Bottai, M., Chiavenna, C., Eliasson, M., Engstrom, G., Hallmans, G., Jansson, J., Magnusson, P. K., Nilsson, P. M., Pedersen, N. L., Wolk, A. & Leander, K., Nov 2017, In: PLoS Medicine. 14, 11

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Does menopausal hormone therapy reduce myocardial infarction risk if initiated early after menopause? A population-based case-control study

    Carrasquilla, Germán D., Berglund, A., Gigante, B., Landgren, B., de Faire, U., Hallqvist, J. & Leander, K., Jun 2015, In: Menopause . 22, 6, p. 598-606

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Estimating causality between smoking and abdominal obesity by Mendelian randomization

    Carrasquilla, Germán D., García Ureña, Mario, Romero Lado, María José & Kilpeläinen, Tuomas O., 2024, In: Addiction. 119, p. 1024-1034

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Mendelian randomization suggests a bidirectional, causal relationship between physical inactivity and adiposity

    Carrasquilla, Germán D., García Ureña, Mario, Fall, T., Sørensen, Thorkild I.A. & Kilpeläinen, Tuomas O., 2022, In: eLife. 11, 25 p., e70386.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Dietary Fat and the Genetic Risk of Type 2 Diabetes

    Carrasquilla, Germán D., Jakupovic, Hermina & Kilpeläinen, Tuomas O., 2019, In: Current Diabetes Reports. 19, 6 p., 109.

    Research output: Contribution to journalReviewResearchpeer-review

  30. Published
  31. Published

    Child-to-adult body size change and risk of type 2 diabetes and cardiovascular disease

    Carrasquilla, Germán D., Ängquist, Lars, Sørensen, Thorkild I.A., Kilpeläinen, Tuomas O. & Loos, Ruth, 2024, In: Diabetologia. 67, p. 864–873 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    The Genetic Basis of Hypertriglyceridemia

    Carrasquilla, Germán D., Christiansen, Malene Revsbech & Kilpeläinen, Tuomas O., 2021, In: Current Atherosclerosis Reports. 23, 10 p., 39.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Estimating the causal relationship between smoking and abdominal adiposity using Mendelian randomization

    Carrasquilla, Germán D., García Ureña, Mario, Sharma, S. & Kilpeläinen, Tuomas O., 2022, Cold Spring Harbor Laboratory, (bioRxiv).

    Research output: Working paperPreprintResearch

  34. Published

    Evidence for L1-associated DNA rearrangements and negligible L1 retrotransposition in glioblastoma multiforme

    Carreira, P. E., Ewing, A. D., Li, G., Schauer, S. N., Upton, K. R., Fagg, A. C., Morell, S., Kindlova, M., Gerdes, P., Richardson, S. R., Li, B., Gerhardt, D. J., Wang, J., Brennan, P. M. & Faulkner, G. J., 2016, In: Mobile D N A. 7, 14 p., 21.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    23, 22 Calling the Microbiota to Control Atherosclerosis

    Carreras, A. & Bäckhed, F., 2018, In: Immunity. 49, 5, p. 788-790 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Exercise Promotes Healthy Aging of Skeletal Muscle

    Cartee, G. D., Hepple, R. T., Bamman, M. M. & Zierath, Juleen R, 14 Jun 2016, In: Cell Metabolism. 23, 6, p. 1034-47 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Short Article Hypothalamic bile acid-TGR5 signaling protects from obesity

    Castellanos-Jankiewicz, A., Guzman-Quevedo, O., Fenelon, V. S., Zizzari, P., Quarta, C., Bellocchio, L., Tailleux, A., Charton, J., Fernandois, D., Henricsson, M., Piveteau, C., Simon, V., Allard, C., Quemener, S., Guinot, V., Hennuyer, N., Perino, A., Duveau, A., Maitre, M., Leste-Lasserre, T. & 13 others, Clark, S., Dupuy, N., Cannich, A., Gonzales, D., Deprez, B., Mithieux, G., Dombrowicz, D., Backhed, F., Prevot, V., Marsicano, G., Staels, B., Schoonjans, K. & Cota, D., 2021, In: Cell Metabolism. 33, 7, p. 1483-1492.e1-e10 21 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    DNA methylation changes at infertility genes in newborn twins conceived by in vitro fertilisation

    Castillo-Fernandez, J. E., Loke, Y. J., Bass-Stringer, S., Gao, F., Xia, Y., Wu, H., Lu, H., Liu, Y., Wang, J., Spector, T. D., Saffery, R., Craig, J. M. & Bell, J. T., 24 Mar 2017, In: Genome Medicine. 9, 15 p., 28.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Secretion of glucagon-like peptide-2 responds to nutrient intake but not glucose provision in milk-fed calves

    Castro, J. J., Morrison, S. Y., Hosseinni, A., Loor, J. J., Drackley, J. K., Ipharraguerre, I. R., Holst, Jens Juul & Hartmann, Bolette, Jul 2016, In: Journal of Dairy Science. 99, 7, p. 5793–5807

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    The human batokine EPDR1 regulates β-cell metabolism and function

    Cataldo Bascunan, Luis Rodrigo, Gao, Q., Argemi Muntadas, Lidia, Hodek, O., Cowan, E., Hladkou, S., Gheibi, S., Spegel, P., Prasad, R. B., Eliasson, L., Schéele, Camilla Charlotte Nielsen, Fex, M., Mulder, H. & Moritz, Thomas, 2022, In: Molecular Metabolism. 66, 14 p., 101629.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    MAFA and MAFB regulate exocytosis-related genes in human β-cells

    Cataldo Bascunan, Luis Rodrigo, Singh, T., Achanta, K., Bsharat, S., Prasad, R. B., Luan, C., Renström, E., Eliasson, L. & Artner, I., 2022, In: Acta Physiologica. 234, 2, 14 p., e13761.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    A Multi-Omics Approach to Liver Diseases: Integration of Single Nuclei Transcriptomics with Proteomics and HiCap Bulk Data in Human Liver

    Cavalli, M., Diamanti, K., Pan, G., Spalinskas, R., Kumar, C., Deshmukh, Atul Shahaji, Mann, Matthias, Sahlén, P., Komorowski, J. & Wadelius, C., 2020, In: O M I C S: A Journal of Integrative Biology. 24, 4, 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Mass spectrometry-based proteomics approaches to interrogate skeletal muscle adaptations to exercise

    Cervone, D. T., Moreno Justicia, Roger, Prats Quesada, Júlia & Deshmukh, Atul Shahaji, 2024, In: Scandinavian Journal of Medicine and Science in Sports. 34, 1, 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    1H MRS Assessment of Hepatic Fat Content. Comparison Between Normal- and Excess-weight Children and Adolescents

    Chabanova, E., Fonvig, Cilius Esmann, Bøjsøe, C., Holm, Jens-Christian & Thomsen, Henrik S., Aug 2017, In: Academic Radiology. 24, 8, p. 982-987 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    MR spectroscopy of liver in overweight children and adolescents: investigation of ¹H T2 relaxation times at 3T

    Chabanova, E., Bille, D. S., Thisted, E., Holm, Jens-Christian & Thomsen, Henrik S., 2012, In: European Journal of Radiology Extra. 81, 5, p. 811-4 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    (1)H MRS assessment of hepatic steatosis in overweight children and adolescents: comparison between 3T and open 1T MR-systems

    Chabanova, E., Bille, D. S., Thisted, E., Holm, Jens-Christian & Thomsen, Henrik S., 2012, In: Abdominal Imaging. 38, 2, p. 315-9 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    The potential of tailoring the gut microbiome to prevent and treat cardiometabolic disease

    Chakaroun, R. M., Olsson, L. M. & Bäckhed, F., 2023, In: Nature Reviews Cardiology. 20, p. 217-235

    Research output: Contribution to journalReviewResearchpeer-review

  48. Published

    Structure-Activity Relationships and Identification of Optmized CC-Chemokine Receptor CCR1, 5, and 8 Metal-Ion Chelators

    Chalikiopoulos, A., Thiele, S., Malmgaard-Clausen, M., Rydberg, P., Isberg, V., Ulven, Trond, Frimurer, Thomas Michael, Rosenkilde, Mette & Gloriam, David E., 25 Nov 2013, In: Journal of Chemical Information and Modeling. 53, 11, p. 2863-73 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Heterogeneity of glucagonomas due to differential processing of proglucagon-derived peptides

    Challis, B. G., Albrechtsen, Nicolai Jacob Wewer, Bansiya, V., Burling, K., Barker, P., Hartmann, Bolette, Gribble, F., O'Rahilly, S., Holst, Jens Juul & Simpson, H. L., 2015, In: Endocrinology, Diabetes & Metabolism Case Reports. 2015, p. 1-7 7 p., 150105.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits

    Chami, N., Chen, M-H., Slater, A. J., Eicher, J. D., Evangelou, E., Tajuddin, S. M., Love-Gregory, L., Kacprowski, T., Schick, U. M., Nomura, A., Giri, A., Lessard, S., Brody, J. A., Schurmann, C., Pankratz, N., Yanek, L. R., Manichaikul, A., Pazoki, R., Mihailov, E., Hill, W. D. & 93 others, Raffield, L. M., Burt, A., Bartz, T. M., Becker, D. M., Becker, L. C., Boerwinkle, E., Bork-Jensen, J., Bottinger, E. P., O'Donoghue, M. L., Crosslin, D. R., de Denus, S., Dubé, M., Elliott, P., Engström, G., Evans, M. K., Floyd, J. S., Fornage, M., Gao, H., Greinacher, A., Gudnason, V., Hansen, Torben, Harris, T. B., Hayward, C., Hernesniemi, J., Highland, H. M., Hirschhorn, J. N., Hofman, A., Irvin, M. R., Kähönen, M., Lange, E., Launer, L. J., Lehtimäki, T., Li, J., Liewald, D. C. M., Linneberg, Allan René, Liu, Y., Lu, Y., Lyytikäinen, L., Mägi, R., Mathias, R. A., Melander, O., Metspalu, A., Mononen, N., Nalls, M. A., Nickerson, D. A., Nikus, K., O'Donnell, C. J., Orho-Melander, M., Pedersen, Oluf Borbye, Petersmann, A., Polfus, L., Psaty, B. M., Raitakari, O. T., Raitoharju, E., Richard, M., Rice, K. M., Rivadeneira, F., Rotter, J. I., Schmidt, F., Smith, A. V., Starr, J. M., Taylor, K. D., Teumer, A., Thuesen, B. H., Torstenson, E. S., Tracy, R. P., Tzoulaki, I., Zakai, N. A., Vacchi-Suzzi, C., van Duijn, C. M., van Rooij, F. J. A., Cushman, M., Deary, I. J., Velez Edwards, D. R., Vergnaud, A., Wallentin, L., Waterworth, D. M., White, H. D., Wilson, J. G., Zonderman, A. B., Kathiresan, S., Grarup, Niels, Esko, T., Loos, R. J. F., Lange, L. A., Faraday, N., Abumrad, N. A., Edwards, T. L., Ganesh, S. K., Auer, P. L., Johnson, A. D., Reiner, A. P. & Lettre, G., 7 Jul 2016, In: American Journal of Human Genetics. 99, 1, p. 8-21 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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