Novo Nordisk Foundation Center for Basic Metabolic Research

  1. Published

    Genome-wide association study of sexual maturation in males and females highlights a role for body mass and menarche loci in male puberty

    The ReproGen Consortium, T. R. C., The Early Growth Genetics (EGG) Consortium, T. E. G. G. (. C., The Early Growth Genetics (EGG) Consortium, T. E. G. G. (. C., The ReproGen Consortium, T. R. C. & The GIANT Consortium, T. G. C., 1 Jan 2014, In: Human Molecular Genetics. 23, 16, p. 4452-4464 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Impact of weight loss achieved through a multidisciplinary intervention on appetite in patients with severe obesity

    Coutinho, S. R., Rehfeld, Jens Frederik, Holst, Jens Juul, Kulseng, B. & Martins, C., Jul 2018, In: American Journal of Physiology: Endocrinology and Metabolism. 315, 1, p. E91-E98

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Modulation of gut microbiota by Mantequilla and Melipona honeys decrease low-grade inflammation caused by high fructose corn syrup or sucrose in rats

    Coutiño-Hernández, D., Sánchez-Tapia, M., Leal-Vega, F., Bobadilla del Valle, M., Ledezma, H., Cervantes, R., Pedraza-Chaverri, J., Granados-Portillo, O., Díaz, D., Antunes-Ricardo, M., Gutiérrez-Uribe, J., Maya, Otoniel, Olin-Sandoval, V., Tovar, A. R. & Torres, N., 2022, In: Food Research International. 151, 13 p., 110856.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Salivary ghrelin response to drinks varying in protein content and quantity and association with energy intake and appetite.

    Crabtree, D. R., Buosi, W., Fyfe, C. L., Horgan, G. W., Holst, Jens Juul, Johnstone, A. M. & Full4Health-study Group, F. G., 2021, In: Physiology and Behavior. 242, 113622.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Appetite Control across the Lifecourse: The Acute Impact of Breakfast Drink Quantity and Protein Content. The Full4Health Project

    Crabtree, D. R., Buosi, W., Fyfe, C. L., Horgan, G. W., Manios, Y., Androutsos, O., Giannopoulou, A., Finlayson, G., Beaulieu, K., Meek, C. L., Holst, Jens Juul, Van Norren, K., Mercer, J. G., Johnstone, A. M. & FullHealth Study Grp, F. S. G., 2020, In: Nutrients. 12, 12, 26 p., 3710.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    The Use of Gastrostomy Tube for the Long-Term Remission of Hyperinsulinemic Hypoglycemia After Roux-en-y Gastric Bypass: A Case Report

    Craig, C., Lamendola, C., Holst, Jens Juul, Deacon, Carolyn F. & McLaughlin, T., 2015, In: AACE Clinical Case Reports. 1, 2, p. e84-e87 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Critical role for GLP-1 in symptomatic post-bariatric hypoglycaemia

    Craig, C. M., Liu, L., Deacon, Carolyn F., Holst, Jens Juul & McLaughlin, T. L., Mar 2017, In: Diabetologia. 60, 3, p. 531-540

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    The effect of gluten in adolescents and young adults with gastrointestinal symptoms: A blinded randomised cross-over trial

    Crawley, C., Savino, N., Halby, C., Sander, S. D., Nybo Andersen, Anne-Marie, Arumugam, Mani, Murray, J., Christensen, R. & Husby, S., 2022, In: Alimentary Pharmacology and Therapeutics, Supplement. 55, 9, p. 1116-1127 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Male reproductive traits are differentially affected by dietary macronutrient balance but unrelated to adiposity

    Crean, A. J., Afrin, S., Niranjan, H., Pulpitel, T. J., Ahmad, G., Senior, A. M., Freire, T., Mackay, F., Nobrega, M. A., Barrès, Romain, Simpson, S. J. & Pini, T., 2023, In: Nature Communications. 14, 1, 12 p., 2566.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Paternal dietary macronutrient balance and energy intake drive metabolic and behavioral differences among offspring

    Crean, A. J., Senior, A. M. N., Freire, T., Clark, T. D., Mackay, F., Austin, G., Pulpitel, T. J., Nobrega, M. A., Barrès, Romain & Simpson, S. J., 2024, In: Nature Communications. 15, 11 p., 2982.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Association and Interaction of Genetics and Area-Level Socioeconomic Factors on the Prevalence of Type 2 Diabetes and Obesity

    Cromer, S. J., Lakhani, C., Mercader, J., Majarian, T., Schroeder, P., Cole, J., Florez, J., Patel, C., Manning, A., Burnett-Bowie, S., Merino, Jordi & Udler, M. S., 2023, In: Diabetes Care. 46, 5, p. 944-952

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Ponderal index at birth associates with later risk of gestational diabetes mellitus

    Crusell, Mie Korslund Wiinblad, Damm, Peter, Hansen, Torben, Pedersen, Oluf Borbye, Glümer, C., Vaag, Allan & Lauenborg, J., Aug 2017, In: Archives of Gynecology and Obstetrics. 296, 2, p. 249-256 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Gestational diabetes and the human salivary microbiota: a longitudinal study during pregnancy and postpartum

    Crusell, M. K. W., Brink, L. R., Nielsen, T., Allin, K. H., Hansen, Torben, Damm, Peter, Lauenborg, J., Hansen, T. H. & Pedersen, Oluf Borbye, 2020, In: BMC Pregnancy and Childbirth. 20, 12 p., 69.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Gestational diabetes is associated with change in the gut microbiota composition in third trimester of pregnancy and postpartum

    Crusell, Mie Korslund Wiinblad, Hansen, T. H., Nielsen, T., Allin, K. H., Rühlemann, M. C., Damm, Peter, drb459, drb459, Rørbye, Christina, Jørgensen, N. R., Christiansen, O. B., Heinsen, F., Franke, A., Hansen, Torben, Lauenborg, J. & Pedersen, Oluf Borbye, 15 May 2018, In: Microbiome. 6, 19 p., 89.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Comparative Studies of the Gut Microbiota in the Offspring of Mothers With and Without Gestational Diabetes

    Crusell, Mie Korslund Wiinblad, Hansen, T. H., Nielsen, T., Allin, K. H., Rühlemann, M. C., Damm, Peter, Vestergaard, H., Rørbye, Christina, Jørgensen, Niklas Rye, Christiansen, O. B., Heinsen, F. A., Franke, A., Hansen, Torben, Lauenborg, J. & Pedersen, Oluf Borbye, 2020, In: Frontiers in Cellular and Infection Microbiology. 10, 14 p., 536282.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Effect of mineralocorticoid receptor antagonists on proteinuria and progression of chronic kidney disease: a systematic review and meta-analysis

    Currie, G., Taylor, A. H. M., Fujita, T., Ohtsu, H., Lindhardt, M., Rossing, Peter, Boesby, L., Edwards, N. C., Ferro, C. J., Townend, J. N., van den Meiracker, A. H., Saklayen, M. G., Oveisi, S., Jardine, A. G., Delles, C., Preiss, D. J. & Mark, P. B., 2016, In: B M C Nephrology. 17, p. 1-14 14 p., 127.

    Research output: Contribution to journalReviewResearchpeer-review

  17. Published

    Crosstalk between tumor acidosis, p53 and extracellular matrix regulates pancreatic cancer aggressiveness

    Czaplinska, D., Ialchina, Renata, Andersen, Henriette Berg, Yao, Jiayi, Stigliani, Arnaud, Dannesboe, Johs, Flinck, M., Chen, X., Mitrega, J., Gnosa, S. P., Dmytriyeva, O., Alves, F., Napp, J., Sandelin, Albin Gustav & Pedersen, Stine Helene Falsig, 2023, In: International Journal of Cancer. 152, 6, p. 1210-1225 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Strenuous physical exercise adversely affects monocyte chemotaxis

    Czepluch, F. S., Barrès, Romain, Caidahl, K., Olieslagers, S., Krook, A., Rickenlund, A., Zierath, Juleen R & Waltenberger, J., Jan 2011, In: Thrombosis and Haemostasis. 105, 1, p. 122-30 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Polygenic predisposition to breast cancer and the risk of coronary artery disease

    D'Souza, M., Schou, Morten, Skals, R., Weeke, P. E., Lee, C., Smedegaard, L., Madelaire, C., Gerds, Thomas Alexander, Poulsen, Henrik Enghusen, Hansen, Torben, Grarup, N., Pedersen, Oluf Borbye, Stender, Steen, Engstrøm, Thomas, Fosbøl, E., Nielsen, D., Gislason, Gunnar Hilmar, Køber, Lars Valeur, Torp-Pedersen, C. & Andersson, C., 2019, In: International Journal of Cardiology. 291, p. 145-151 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Monogenic diabetes variants in Emirati women with gestational diabetes are associated with risk of non-autoimmune diabetes within 5 years after pregnancy

    Daggag, H., Gjesing, A. P., Mohammad, A., Ängquist, Lars, Shobi, B., Antony, S., Haj, D., Al Tikriti, A., Buckley, A., Hansen, Torben & Barakat, M. T., 2022, In: Metabolism open. 16, 7 p., 100213.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Habitual sleep disturbances and migraine: a Mendelian randomization study

    Daghlas, I., Vgontzas, A., Guo, Y., Chasman, D. I., Saxena, R., Pers, Tune H & International Headache Genetics Consortium, I. H. G. C., 2020, In: Annals of Clinical and Translational Neurology. 7, 12, p. 2370-2380 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Effects of lifestyle intervention in tissue‐specific lipidomic profile of formerly obese mice

    Dahdah, N., Gonzalez‐franquesa, A., Samino, S., Gama‐perez, P., Herrero, L., Perales, J. C., Yanes, O., Malagón, M. D. M. & Garcia‐roves, P. M., 2021, In: International Journal of Molecular Sciences. 22, 7, 18 p., 3694.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Subclinical Hypothyroidism in Danish Lean and Obese Children and Adolescents

    Dahl, M., Ohrt, J. D., Fonvig, C. E., Kloppenborg, J. T., Pedersen, Oluf Borbye, Hansen, Torben & Holm, Jens-Christian, 1 Mar 2017, In: JCRPE Journal of Clinical Research in Pediatric Endocrinology. 9, 1, p. 8-16 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    HDAC Inhibitor-Mediated Beta-Cell Protection Against Cytokine-Induced Toxicity Is STAT1 Tyr701 Phosphorylation Independent

    Dahllöf, M. S., Christensen, D. P., Harving, M., Wagner, B. K., Mandrup-Poulsen, Thomas & Lundh, M., 13 Jan 2015, In: Journal of Interferon & Cytokine Research. 35, 1, p. 63-70 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    A common haplotype in the G-protein-coupled receptor gene GPR74 is associated with leanness and increased lipolysis

    Dahlman, I., Dicker, A., Jiao, H., Kere, J., Blomqvist, L., van Harmelen, V., Hoffstedt, J., Borch-Johnsen, K., Jorgensen, T., Hansen, Torben, Pedersen, Oluf Borbye, Laakso, M. & Arner, P., 2007, In: American Journal of Human Genetics. 80, 6, p. 1115-24 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Adipose tissue fatty acid patterns and changes in anthropometry: a cohort study

    Dahm, C. C., Gorst-Rasmussen, A., Jakobsen, M. U., Schmidt, E. B., Tjønneland, A., Sørensen, Thorkild I.A. & Overvad, K., 2011, In: P L o S One. 6, 7, p. e22587

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Voluntary wheel running in the late dark phase ameliorates diet-induced obesity in mice without altering insulin action

    Kellezi, Emilie Dalbram, Basse, A. L., Zierath, Juleen R & Treebak, Jonas Thue, 2019, In: Journal of Applied Physiology. 126, 4, p. 993-1005 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Neuromedin U inhibits food intake partly by inhibiting gastric emptying

    Dalbøge, L. S., Pedersen, S. L., Secher, T., Holst, Birgitte, Vrang, N. & Jelsing, J., Jul 2015, In: Peptides. 69, p. 56-65 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    A prevalent polymorphism in the putative promotor of the UCP3 gene and its relationship to body mass index in the Danish population

    Dalgaard, L. T., Sørensen, Thorkild I.A., Drivsholm, T. B., Borch-Johnsen, K., Andersen, T., Hansen, T. & Pedersen, Oluf Borbye, 2001, In: Journal of Clinical Endocrinology and Metabolism. 86, p. 1398-1402

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Intermediate Expansions of a GAA Repeat in the Frataxin Gene are not associated with Type 2 Diabetes or Altered Glucose-Induced ¿-cell function in Danish Caucasians

    Dalgaard, L. T., Hansen, T., Urhammer, S. A., Clausen, J. O., Eiberg, Hans Rudolf Lytchoff & Pedersen, Oluf Borbye, 1999, In: Diabetes. 48, p. 914-917

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Hepatocyte-specific perturbation of NAD+ biosynthetic pathways in mice induces reversible nonalcoholic steatohepatitis-like phenotypes

    Dall, M., Hassing, Anna Skab, Niu, Lili, Nielsen, Thomas Svava, Ingerslev, L. R., Sulek, K., Trammell, Sam, Gillum, M. P., Barrès, Romain, Larsen, Steen, Poulsen, Steen Seier, Mann, Matthias, Ørskov, Cathrine & Treebak, Jonas Thue, 2021, In: Journal of Biological Chemistry. 297, 6, 26 p., 101388.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    NAD+ and NAFLD - Caution, Causality, and Careful Optimism

    Dall, M., Hassing, Anna Skab & Treebak, Jonas Thue, 2022, In: The Journal of Physiology. 600, 5, p. 1135-1154

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Denmark's big tent includes postdocs

    Dall, M. & Pedersen, M. H., 2023, In: Science. 380, 6641, p. 143 1 p.

    Research output: Contribution to journalLetterResearchpeer-review

  34. Published

    Hepatic NAD+ levels and NAMPT abundance are unaffected during prolonged high-fat diet consumption in C57BL/6JBomTac mice

    Dall, M., Penke, M., Sulek, K., Matz-Soja, M., Holst, Birgitte, Garten, A., Kiess, W. & Treebak, Jonas Thue, 2018, In: Molecular and Cellular Endocrinology. 473, p. 245-256 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Mitochondrial function in liver cells is resistant to perturbations in NAD+ salvage capacity

    Dall, M., Trammell, Sam, Asping, M., Hassing, Anna Skab, Agerholm, M., Vienberg, S. G., Gillum, M. P., Larsen, Steen & Treebak, Jonas Thue, 2019, In: The Journal of Biological Chemistry. 294, 36, p. 13304-13326 23 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Dysregulation of a long noncoding RNA reduces leptin leading to a leptin-responsive form of obesity

    Dallner, O. S., Marinis, J. M., Lu, Y., Birsoy, K., Werner, E., Fayzikhodjaeva, G., Dill, B. D., Molina, H., Moscati, A., Kutalik, Z., Marques-Vidal, P., Kilpeläinen, Tuomas O., Grarup, N., Linneberg, Allan René, Zhang, Y., Vaughan, R., Loos, Ruth, Lazar, M. A. & Friedman, J. M., 2019, In: Nature Medicine. 25, 3, p. 507-530 24 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    The role of GLP-1 in the postprandial effects of acarbose in type 2 diabetes

    Dalsgaard, N. B., Gasbjerg, Lærke Smidt, Hansen, L. S., Hansen, N. L., Stensen, S., Hartmann, Bolette, Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2021, In: European Journal of Endocrinology. 184, 3, p. 387-398 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Effects of glucagon-like peptide-1 receptor agonists on cardiovascular risk factors: A narrative review of head-to-head comparisons

    Dalsgaard, N. B., Vilsbøll, Tina & Knop, Filip Krag, Mar 2018, In: Diabetes, Obesity and Metabolism. 20, 3, p. 508-519

    Research output: Contribution to journalReviewResearchpeer-review

  39. Published

    Cardiovascular safety and benefits of GLP-1 receptor agonists

    Dalsgaard, N. B., Brønden, A., Vilsbøll, Tina & Knop, Filip Krag, 2017, In: Expert Opinion on Drug Safety. 16, 3, p. 351-363 13 p.

    Research output: Contribution to journalReviewResearchpeer-review

  40. Published

    Acarbose diminishes postprandial suppression of bone resorption in patients with type 2 diabetes

    Dalsgaard, N. B., Gasbjerg, Lærke Smidt, Helsted, M. M., Hansen, L. S., Hansen, N. L., Skov-Jeppesen, Kirsa, Hartmann, Bolette, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2023, In: Bone. 170, 116687.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Age-dependent alterations of glucose clearance and homeostasis are temporally separated and modulated by dietary fat

    Damgaard, Mads Vargas, Pærregaard, S. I., Søgaard, I., Andersen, M. A., Paulson, J. N., Treebak, Jonas Thue, Sina, C., Holm, J. B., Kristiansen, Karsten & Jensen, Benjamin Anderschou Holbech, 2018, In: Journal of Nutritional Biochemistry. 54, p. 66-76 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Pterostilbene Fails to Rescue Insulin Secretion and Sensitivity in Multiple Murine Models of Diabetes

    Damgaard, Mads Vargas, Jepsen, Sara Lind, Ashcroft, Stephen Paul, Holst, Jens Juul & Treebak, Jonas Thue, 2022, In: Nutrients. 14, 18, 11 p., 3741.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    What is really known about the effects of nicotinamide riboside supplementation in humans

    Damgaard, Mads Vargas & Treebak, Jonas Thue, 2023, In: Science Advances. 9, 29, 12 p., eadi4862.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Protocol for qPCR analysis that corrects for cDNA amplification efficiency

    Damgaard, Mads Vargas & Treebak, Jonas Thue, 2022, In: STAR Protocols. 3, 3, 11 p., 101515.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Intravenous nicotinamide riboside elevates mouse skeletal muscle NAD+ without impacting respiratory capacity or insulin sensitivity

    Damgaard, Mads Vargas, Nielsen, Thomas Svava, Basse, A. L., Chubanava, Sabina, Trost, K., Moritz, Thomas, Dellinger, R. W., Larsen, Steen & Treebak, Jonas Thue, 2022, In: iScience. 25, 2, 21 p., 103863.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Effects of oleic acid and olive oil on gastric emptying, gut hormone secretion and appetite in lean and overweight or obese males

    Damgaard, Morten, Graff, J., Fuglsang, S., Holst, Jens Juul, Rehfeld, Jens Frederik & Madsen, J. L., 2013, In: e - S P E N Journal. 8, 1, p. e8-e14 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Acetylcholine-related proteins in non-neoplastic appearing colonic mucosa from patients with colorectal neoplasia

    Damm, M. M. B., Jensen, T. S. R., Mahmood, B., Lundh, M., Poulsen, Steen Seier, Bindslev, Niels & Hansen, M. B., 2017, In: Molecular Carcinogenesis. 56, 10, p. 2223-2233 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Impaired insulin-stimulated nonoxidative glucose metabolism in glucose-tolerant women with previous gestational diabetes

    Damm, Peter, drb459, drb459, Kühl, C. E. & Pedersen, Oluf Borbye, Feb 1996, In: American Journal of Obstetrics and Gynecology. 174, 2, p. 722-9 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    A century of trends in adult human height

    Damsgaard, Camilla Trab, Michaelsen, Kim F., Molbo, Drude, Mortensen, Erik Lykke, Sørensen, Thorkild I.A. & NCD Risk Factor Collaboration (NCD-RisC), N. R. F. C. (., 26 Jul 2016, In: eLife. 5, 29 p., e13410.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Trends in adult body-mass index in 200 countries from 1975 to 2014: A pooled analysis of 1698 population-based measurement studies with 19.2 million participants

    Damsgaard, Camilla Trab, Michaelsen, Kim F., Molbo, Drude, Mortensen, Erik Lykke, Sørensen, Thorkild I.A. & NCD Risk Factor Collaboration (NCD-RisC), N. R. F. C. (., 2016, In: The Lancet. 387, 10026, p. 1377-1396 20 p.

    Research output: Contribution to journalJournal articleResearchpeer-review