Novo Nordisk Foundation Center for Basic Metabolic Research

  1. Published

    Should Europe follow the US and declare obesity a disease? A discussion of the so-called utilitarian argument

    Vallgårda, Signild, Nielsen, Morten Ebbe Juul, Hansen, A. K. K., Ó Cathaoir, Katharina, Hartlev, Mette, Holm, Lotte, Christensen, Bodil Just, Jensen, Jørgen Dejgård, Sørensen, Thorkild I.A. & Sandøe, Peter, 2017, In: European Journal of Clinical Nutrition. 71, p. 1263–1267 5 p.

    Research output: Contribution to journalReviewResearchpeer-review

  2. Published

    Duodenal L cell density correlates with features of metabolic syndrome and plasma metabolites

    Van Baar, A. C. G., Prodan, A., Wahlgren, C. D., Poulsen, Steen Seier, Knop, Filip Krag, Groen, A. K., Bergman, J. J., Nieuwdorp, M. & Levin, E., 2018, In: Endocrine Connections. 7, 5, p. 673-680

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    A Previously Undescribed Highly Prevalent Phage Identified in a Danish Enteric Virome Catalog

    Van Espen, L., Bak, E. G., Beller, L., Close, L., Deboutte, W., Juel, H. B., Nielsen, T., Sinar, D., De Coninck, L., Frithioff-Bøjsøe, C., Fonvig, C. E., Jacobsen, S., Kjærgaard, M., Thiele, M., Fullam, A., Kuhn, M., Holm, J. C., Bork, P., Krag, A., Hansen, T. & 2 others, Arumugam, Mani & Matthijnssens, J., 2021, In: mSystems. 6, 5, 20 p., e00382-21.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Reduced obesity, diabetes, and steatosis upon cinnamon and grape pomace are associated with changes in gut microbiota and markers of gut barrier

    Van Hul, M., Geurts, L., Plovier, H., Druart, C., Everard, A., Ståhlman, M., Rhimi, M., Chira, K., Teissedre, P., Delzenne, N. M., Maguin, E., Guilbot, A., Brochot, A., Gérard, P., Bäckhed, F. & Cani, P. D., 2018, In: American Journal of Physiology: Endocrinology and Metabolism. 314, 4, p. E334-E352 19 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Genome of the Netherlands population-specific imputations identify an ABCA6 variant associated with cholesterol levels

    Van Leeuwen, E. M., Karssen, L. C., Deelen, J., Isaacs, A., Medina-Gomez, C., Mbarek, H., Kanterakis, A., Trompet, S., Postmus, I., Verweij, N., Van Enckevort, D. J., Huffman, J. E., White, C. C., Feitosa, M. F., Bartz, T. M., Manichaikul, A., Joshi, P. K., Peloso, G. M., Deelen, P., Van Dijk, F. & 105 others, Willemsen, G., De Geus, E. J., Milaneschi, Y., Penninx, B. W. J. H., Francioli, L. C., Menelaou, A., Pulit, S. L., Rivadeneira, F., Hofman, A., Oostra, B. A., Franco, O. H., Leach, I. M., Beekman, M., De Craen, A. J. M., Uh, H. W., Trochet, H., Hocking, L. J., Porteous, D. J., Sattar, N., Packard, C. J., Buckley, B. M., Brody, J. A., Bis, J. C., Rotter, J. I., Mychaleckyj, J. C., Campbell, H., Duan, Q., Lange, L. A., Wilson, J. F., Hayward, C., Polasek, O., Vitart, V., Rudan, I., Wright, A. F., Rich, S. S., Psaty, B. M., Borecki, I. B., Kearney, P. M., Stott, D. J., Cupples, L. A., Jukema, J. W., Van Der Harst, P., Sijbrands, E. J., Hottenga, J. J., Uitterlinden, A. G., Swertz, M. A., Van Ommen, G. J. B., De Bakker, P. I. W., Eline Slagboom, P., Boomsma, D. I., Wijmenga, C., Van Duijn, C. M., Neerincx, P. B. T., Elbers, C. C., Palamara, P. F., Peer, I., Abdellaoui, A., Kloosterman, W. P., Van Oven, M., Vermaat, M., Li, M., Laros, J. F. J., Stoneking, M., De Knijff, P., Kayser, M., Veldink, J. H., Van Den Berg, L. H., Byelas, H., Den Dunnen, J. T., Dijkstra, M., Amin, N., Van Der Velde, K. J., Van Setten, J., Kattenberg, M., Van Schaik, B. D. C., Bot, J., Nijman, I. J., Mei, H., Koval, V., Ye, K., Lameijer, E. W., Moed, M. H., Hehir-Kwa, J. Y., Handsaker, R. E., Sunyaev, S. R., Sohail, M., Hormozdiari, F., Marschall, T., Schönhuth, A., Guryev, V., Suchiman, H. E. D., Wolffenbuttel, B. H., Platteel, M., Pitts, S. J., Potluri, S., Cox, D. R., Li, Q., Li, Y., Du, Y., Chen, R., Cao, H., Li, N., Cao, S., Wang, J. & Bovenberg, J. A., 2015, In: Nature Communications. 6, 6 p., 6065.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    A systems biology approach to understand gut microbiota and host metabolism in morbid obesity: design of the BARIA Longitudinal Cohort Study

    Van Olden, C. C., Van de Laar, A. W., Meijnikman, A. S., Aydin, O., Van Olst, N., Hoozemans, J. B., De Brauw, L. M., Bruin, S. C., Acherman, Y. I. Z., Verheij, J., Pyykko, J. E., Hagedoorn, M., Sanderman, R., Bosma, N. C., Tremaroli, V., Lundqvist, A., Olofsson, L. E., Herrema, H., Lappa, D., Hjorth, S. & 6 others, Nielsen, J., Schwartz, Thue W., Groen, A. K., Nieuwdorp, M., Backhed, F. & Gerdes, V. E. A., 2021, In: Journal of Internal Medicine. 289, 3, p. 340-354 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    A genome-wide association study of diabetic kidney disease in subjects with type 2 diabetes

    Van Zuydam, N. R., Ahlqvist, E., Sandholm, N., Deshmukh, H., William Rayner, N., Abdalla, M., Ladenvall, C., Ziemek, D., Fauman, E., Robertson, N. R., McKeigue, P. M., Valo, E., Forsblom, C., Harjutsalo, V., Perna, A., Rurali, E., Loredana Marcovecchio, M., Igo, R. P., Lajer, M., Ahluwalia, T. S. & 7 others, Linneberg, Allan René, Witte, D. R., Grarup, N., Pedersen, Oluf Borbye, Hansen, Torben, Rossing, Peter & SUrrogate markers for Micro- and Macrovascular hard endpoints for Innovative diabetes Tools (SUMMIT) Consortium, S. M. F. M. A. M. H. E. F. I. D. T. (. C., 2018, In: Diabetes. 67, 7, p. 1414-1427 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Vagal afferent cholecystokinin receptor activation is required for glucagon-like peptide-1–induced satiation

    Vana, V., Lærke, M. K., Rehfeld, Jens Frederik, Arnold, M., Dmytriyeva, O., Langhans, W., Schwartz, Thue W. & Hansen, Harald S., 2022, In: Diabetes, Obesity and Metabolism. 24, 2, p. 268-280

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Post-oral fat-induced satiation is mediated by endogenous CCK and GLP-1 in a fat self-administration mouse model

    Vana, V., Lærke, M. K., Kleberg, K., Mroz, P. A., Lindberg, B. L., Ekberg, J. H., Rehfeld, Jens Frederik, Schwartz, Thue W. & Hansen, Harald S., 2021, In: Physiology and Behavior. 234, 12 p., 113315.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Serotonin receptor 4 agonism prevents high fat diet induced reduction in GLP-1 in mice

    Vanslette, A. M., Toft, P. B., Lund, M. L., Moritz, Thomas & Arora, Tulika, 2023, In: European Journal of Pharmacology. 960, 176181.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Effects of sitagliptin and metformin treatment on incretin hormone and insulin secretory responses to oral and "isoglycemic" intravenous glucose

    Vardarli, I., Arndt, E., Deacon, Carolyn F., Holst, Jens Juul & Nauck, M. A., Feb 2014, In: Diabetes. 63, 2, p. 663-74 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Inhibition of DPP-4 with vildagliptin improved insulin secretion in response to oral as well as "isoglycemic" intravenous glucose without numerically changing the incretin effect in patients with type 2 diabetes

    Vardarli, I., Nauck, M. A., Köthe, L. D., Deacon, Carolyn F., Holst, Jens Juul, Schweizer, A. & Foley, J. E., 2011, In: Journal of Clinical Endocrinology and Metabolism. 96, 4, p. 945-954 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Association between parental history of diabetes and type 2 diabetes genetic risk scores in the PPP-Botnia and Framingham Offspring Studies

    Vassy, J. L., Shrader, P., Jonsson, Anna Elisabet, Fox, C. S., Lyssenko, V., Isomaa, B., Groop, L., Meigs, J. B. & Franks, P. W., Aug 2011, In: Diabetes Research and Clinical Practice. 93, 2, p. e76-9

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Solute carrier family 2 member 1 is involved in the development of nonalcoholic fatty liver disease

    Vazquez-Chantada, M., Gonzalez-Lahera, A., Martinez-Arranz, I., Garcia-Monzon, C., Regueiro, M. M., Garcia-Rodriguez, J. L., Schlangen, K. A., Mendibil, I., Rodriguez-Ezpeleta, N., Lozano, J. J., Banasik, K., Justesen, J. M., Jørgensen, T., Witte, D. R., Lauritzen, T., Hansen, T., Pedersen, O., Veyrie, N., Clement, K., Tordjman, J. & 12 others, Tran, A., Le Marchand-Brustel, Y., Buque, X., Aspichueta, P., Echevarria-Uraga, J. J., Martin-Duce, A., Caballeria, J., Gual, P., Castro, A., Mato, J. M., Martinez-Chantar, M. L. & Aransay, A. M., Feb 2013, In: Hepatology. 57, 2, p. 505-514 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Major rapid weight loss induces changes in cardiac repolarization

    Vedel-Larsen, E., Iepsen, E. P. W., Lundgren, J., Graff, C., Struijk, J. J., Hansen, Torben, Holst, Jens Juul, Madsbad, Sten, Torekov, Signe Sørensen & Kanters, Jørgen K., 10 Feb 2016, In: Journal of Electrocardiology. 49, 3, p. 467-472 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    One Year's Treatment with the Glucagon-Like Peptide 1 Receptor Agonist Liraglutide Decreases Hepatic Fat Content in Women with Nonalcoholic Fatty Liver Disease and Prior Gestational Diabetes Mellitus in a Randomized, Placebo-Controlled Trial

    Vedtofte, L., Bahne, E., Foghsgaard, S., Bagger, J. I., Andreasen, C., Strandberg, C., Gortz, P. M., Holst, Jens Juul, Gronbaek, H., Svare, J. A., Clausen, Tine Dalsgaard, Mathiesen, Elisabeth, Damm, Peter, Gluud, Lise Lotte, Knop, Filip Krag & Vilsbøll, Tina, 2020, In: Journal of Clinical Medicine. 9, 10, 14 p., 3213.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Efficacy and safety of fixed-ratio combination of insulin degludec and liraglutide (IDegLira) for the treatment of type 2 diabetes

    Vedtofte, L., Knop, Filip Krag & Vilsbøll, Tina, Mar 2017, In: Expert Opinion on Drug Safety. 16, 3, p. 387-396 10 p.

    Research output: Contribution to journalReviewResearchpeer-review

  18. Published

    Ghrelin secretion in humans - a role for the vagus nerve?

    Veedfald, Simon, Plamboeck, A., Hartmann, Bolette, Vilsbøll, Tina, Knop, Filip Krag, Deacon, Carolyn F., Svendsen, Lars Bo & Holst, Jens Juul, Jun 2018, In: Neurogastroenterology and Motility. 30, 6, e13295.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Hyperosmolar Duodenal Saline Infusion Lowers Circulating Ghrelin and Stimulates Intestinal Hormone Release in Young Men

    Veedfald, Simon, Wu, T., Bound, M., Grivell, J., Hartmann, Bolette, Rehfeld, Jens Frederik, Deacon, Carolyn F., Horowitz, M., Holst, Jens Juul & Rayner, C. K., 2018, In: Journal of Clinical Endocrinology & Metabolism. 103, 12, p. 4409-4418

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Glucose-Dependent Insulinotropic Polypeptide Is a Pancreatic Polypeptide Secretagogue in Humans

    Veedfald, Simon, Vedtofte, L., Skov-Jeppesen, Kirsa, Deacon, Carolyn F., Hartmann, Bolette, Vilsbøll, Tina, Knop, Filip Krag, Christensen, Mikkel Bring & Holst, Jens Juul, 2020, In: Journal of Clinical Endocrinology and Metabolism. 105, 3, p. e502-e510

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Glucose homeostasis and the gastrointestinal tract

    Veedfald, Simon, Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, 2019, Molecular Nutrition Carbohydrates. Elsevier, p. 3-19 17 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  22. Published

    Pancreatic polypeptide responses to isoglycemic oral and intravenous glucose in humans with and without intact vagal innervation

    Veedfald, Simon, Plamboeck, A., Hartmann, Bolette, Svendsen, Lars Bo, Vilsbøll, T., Knop, Filip Krag & Holst, Jens Juul, Sep 2015, In: Peptides. 71, p. 229-31 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Pancreatic polypeptide: A potential biomarker of glucose-dependent insulinotropic polypeptide receptor activation in vivo

    Veedfald, Simon, Bergmann, N. C., Vilsbøll, Tina, Christensen, Mikkel Bring, Holst, Jens Juul & Knop, Filip Krag, May 2021, In: Diabetic Medicine Online. 38, 8, e14592.

    Research output: Contribution to journalLetterResearchpeer-review

  24. Published

    Gut hormone secretion, gastric emptying and glucose absorption after frequently sampled oral glucose and liquid mixed meal tests in young men: [Meeting Abstract]

    Veedfald, Simon, Rehfeld, Jens Frederik, vanHall, G., Svendsen, Lars Bo & Holst, Jens Juul, 2020, In: Neurogastroenterology and Motility. 32, SI, p. 56 1 p., 146.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  25. Published

    Cephalic phase secretion of insulin and other enteropancreatic hormones in humans

    Veedfald, Simon, Plamboeck, A., Deacon, Carolyn F., Hartmann, Bolette, Knop, Filip Krag, Vilsbøll, Tina & Holst, Jens Juul, 1 Jan 2016, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 310, 1, p. G43-51

    Research output: Contribution to journalJournal articleResearchpeer-review