Novo Nordisk Foundation Center for Basic Metabolic Research

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  1. Published

    Whole exome sequencing identified a novel splice donor site variant in interleukin 2 receptor alpha chain

    Waheed, N., Naseer, M., Haider, N., Suleman, Sufyan & Ullah, A., 2023, In: Immunogenetics. 75, p. 71-79

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Production of deoxycholic acid by low-abundant microbial species is associated with impaired glucose metabolism

    Wahlström, A., Brumbaugh, A., Sjöland, W., Olsson, L., Wu, H., Henricsson, M., Lundqvist, A., Makki, K., Hazen, S. L., Bergström, G., Marschall, H. U., Fischbach, M. A. & Bäckhed, F., 2024, In: Nature Communications. 15, 11 p., 4276.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Crosstalk between Bile Acids and Gut Microbiota and Its Impact on Farnesoid X Receptor Signalling

    Wahlström, A., Kovatcheva-Datchary, P., Ståhlman, M., Bäckhed, F. & Marschall, H. U., Mar 2017, In: Digestive Diseases. 35, 3, p. 246-250 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Cyp3a11 is not essential for the formation of murine bile acids

    Wahlström, A., Al-Dury, S., Ståhlman, M., Bäckhed, F. & Marschall, H., Jul 2017, In: Biochemistry and Biophysics Reports. 10, p. 70-75 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Induction of farnesoid X receptor signaling in germ-free mice colonized with a human microbiota

    Wahlström, A., Kovatcheva-Datchary, P., Ståhlman, M., Khan, M., Bäckhed, G. F. & Marschall, H., Feb 2017, In: Journal of Lipid Research. 58, 2, p. 412-419 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Intestinal Crosstalk between Bile Acids and Microbiota and Its Impact on Host Metabolism

    Wahlström, A., Sayin, S. I., Marschall, H. & Bäckhed, G. F., 12 Jul 2016, In: Cell Metabolism. 24, 1, p. 41-50 10 p.

    Research output: Contribution to journal › Review › Research › peer-review

  7. Published

    Genome-wide association study of the modified Stumvoll Insulin Sensitivity Index identifies BCL2 and FAM19A2 as novel insulin sensitivity loci

    Walford, G. A., Gustafsson, S., Rybin, D., Stančáková, A., Chen, H., Liu, C-T., Hong, J., Jensen, R. A., Rice, K., Morris, A. P., Mägi, R., Tönjes, A., Prokopenko, I., Kleber, M. E., Delgado, G., Silbernagel, G., Jackson, A. U., Appel, E. V., Grarup, N., Lewis, J. P. & 59 others, Montasser, M. E., Landenvall, C., Staiger, H., Luan, J., Frayling, T. M., Weedon, M. N., Xie, W., Morcillo, S., Martínez-Larrad, M. T., Biggs, M. L., Ida Chen, Y., Corbaton-Anchuelo, A., Faerch, K., Zumaquero, J. M., Goodarzi, M. O., Kizer, J., Koistinen, H. A., Leong, A., Lind, L., Lindgren, C., Machicao, F., Manning, A. K., Martín-Núñez, G. M., Rojo-Martínez, G., Rotter, J. I., Siscovick, D. S., Zmuda, J. M., Zhang, Z., Serrano-Rios, M., Smith, U., Soriguer, F., Hansen, Torben, Jørgensen, T., Linnenberg, A., Pedersen, Oluf Borbye, Walker, M., Langenberg, C., Scott, R. A., Wareham, N. J., Fritsche, A., Häring, H., Stefan, N., Groop, L., O'Connell, J. R., Boehnke, M., Bergman, R. N., Collins, F. S., Mohlke, K. L., Tuomilehto, J., März, W., Kovacs, P., Stumvoll, M., Psaty, B. M., Kuusisto, J., Laakso, M., Meigs, J. B., Dupuis, J., Ingelsson, E. & Florez, J. C., Oct 2016, In: Diabetes. 65, 10, p. 3200-3211 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    CRISPR-engineered human brown-like adipocytes prevent diet-induced obesity and ameliorate metabolic syndrome in mice

    Wang, C., Lundh, M., Fu, A., Kriszt, R., Huang, T. L., Lynes, M. D., Leiria, L. O., Shamsi, F., Darcy, J., Greenwood, B. P., Narain, N. R., Tolstikov, V., Smith, K. L., Emanuelli, Brice, Chang, Y., Hagen, S., Danial, N. N., Kiebish, M. A. & Tseng, Y., 2020, In: Science Translational Medicine. 12, 558, 15 p., eaaz8664.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Plasma metabolomic profiles associated with mortality and longevity in a prospective analysis of 13,512 individuals

    Wang, F., Tessier, A. J., Liang, L., Wittenbecher, C., Haslam, D. E., Fernández-Duval, G., Heather Eliassen, A., Rexrode, K. M., Tobias, D. K., Li, J., Zeleznik, O., Grodstein, F., Martínez-González, M. A., Salas-Salvadó, J., Clish, C., Lee, K. H., Sun, Q., Stampfer, M. J., Hu, F. B. & Guasch Ferre, Marta, 2023, In: Nature Communications. 14, 1, 11 p., 5744.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Exercise effects on γ3-AMPK activity, Akt substrate of 160 kDa phosphorylation, and glucose uptake in muscle of normal and insulin-resistant female rats

    Wang, H., Arias, E. B., Treebak, Jonas Thue & Cartee, G. D., 2022, In: Journal of Applied Physiology. 132, 1, p. 140-153 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Multi-ancestry genome-wide gene-sleep interactions identify novel loci for blood pressure

    Wang, H., Noordam, R., Cade, B. E., Schwander, K., Winkler, T. W., Lee, J., Sung, Y. J., Bentley, A. R., Manning, A. K., Aschard, H., Kilpeläinen, T. O., Ilkov, M., Brown, M. R., Horimoto, A. R., Richard, M., Bartz, T. M., Vojinovic, D., Lim, E., Nierenberg, J. L., Liu, Y. & 105 others, Chitrala, K., Rankinen, T., Musani, S. K., Franceschini, N., Rauramaa, R., Alver, M., Zee, P. C., Harris, S. E., van der Most, P. J., Nolte, I. M., Munroe, P. B., Palmer, N. D., Kühnel, B., Weiss, S., Wen, W., Hall, K. A., Lyytikäinen, L., O'Connell, J., Eiriksdottir, G., Launer, L. J., de Vries, P. S., Arking, D. E., Chen, H., Boerwinkle, E., Krieger, J. E., Schreiner, P. J., Sidney, S., Shikany, J. M., Rice, K., Chen, Y. I., Gharib, S. A., Bis, J. C., Luik, A. I., Ikram, M. A., Uitterlinden, A. G., Amin, N., Xu, H., Levy, D., He, J., Lohman, K. K., Zonderman, A. B., Rice, T. K., Sims, M., Wilson, G., Sofer, T., Rich, S. S., Palmas, W., Yao, J., Guo, X., Rotter, J. I., Biermasz, N. R., Mook-Kanamori, D. O., Martin, L. W., Barac, A., Wallace, R. B., Gottlieb, D. J., Komulainen, P., Heikkinen, S., Mägi, R., Milani, L., Metspalu, A., Starr, J. M., Milaneschi, Y., Waken, R. J., Gao, C., Waldenberger, M., Peters, A., Strauch, K., Meitinger, T., Roenneberg, T., Völker, U., Dörr, M., Shu, X., Mukherjee, S., Hillman, D. R., Kähönen, M., Wagenknecht, L. E., Gieger, C., Grabe, H. J., Zheng, W., Palmer, L. J., Lehtimäki, T., Gudnason, V., Morrison, A. C., Pereira, A. C., Fornage, M., Psaty, B. M., van Duijn, C. M., Liu, C., Kelly, T. N., Evans, M. K., Bouchard, C., Fox, E. R., Kooperberg, C., Zhu, X., Lakka, T. A., Esko, T., North, K. E., Deary, I. J., Snieder, H., Penninx, B. W. J. H., Gauderman, W. J., Rao, D. C., Redline, S. & van Heemst, D., 2021, In: Molecular Psychiatry. 26, p. 6293-6304

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Meal timing of dietary total antioxidant capacity and its association with all-cause, CVD and cancer mortality: the US national health and nutrition examination survey, 1999–2018

    Wang, P., Jiang, Xuye, Tan, Q., Du, S. & Shi, D., 2023, In: International Journal of Behavioral Nutrition and Physical Activity. 20, 13 p., 83.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Androgen receptor and nutrient signaling pathways coordinate the demand for increased amino acid transport during prostate cancer progression

    Wang, Q., Bailey, C. G., Ng, C., Tiffen, J., Thoeng, A., Minhas, V., Lehman, M. L., Hendy, S. C., Buchanan, G., Nelson, C. C., Rasko, J. E. J., Holst, J. & Holst, Jens Juul, 2011, In: Cancer Research. 71, 24, p. 7525-7536 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Sucrose synthase activity is not required for cellulose biosynthesis in Arabidopsis

    Wang, W., Viljamaa, S., Hodek, O., Moritz, Thomas & Niittylä, T., 2022, In: Plant Journal. 110, 5, p. 1493-1497

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Aberrant gut microbiota alters host metabolome and impacts renal failure in humans and rodents

    Wang, X., Yang, S., Li, S., Zhao, L., Hao, Y., Qin, J., Zhang, L., Zhang, C., Bian, W., Zuo, L. I., Gao, X., Zhu, B., Lei, X., Gu, Z., Cui, W., Xu, X., Li, Z., Zhu, B., Li, Y., Chen, S. & 24 others, Guo, H., Zhang, H., Sun, Jing, Zhang, M., Hui, Y., Zhang, X., Liu, X., Sun, B., Wang, L., Qiu, Q., Zhang, Y., Li, X., Liu, W., Xue, R., Wu, H., Shao, D., Li, J., Zhou, Y., Li, S., Yang, R., Pedersen, Oluf Borbye, Yu, Z., Ehrlich, S. D. & Ren, F., 2020, In: Gut. 69, 12, p. 2131-2142 319766.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Global Biobank analyses provide lessons for developing polygenic risk scores across diverse cohorts

    Wang, Y., Namba, S., Lopera-Maya, E. A., Kerminen, S., Tsuo, K., Läll, K., Kanai, M., Zhou, W., Wu, K. H. H., Favé, M. J., Bhatta, L., Awadalla, P., Brumpton, B. M., Deelen, P., Hveem, K., Lo Faro, V., Mägi, R., Murakami, Y., Sanna, S., Smoller, J. W. & 49 others, Uzunovic, J., Wolford, B. N., Wu, K. H. H., Rasheed, H., Hirbo, J. B., Bhattacharya, A., Zhao, H., Surakka, I., Lopera-Maya, E. A., Chapman, S. B., Karjalainen, J., Kurki, M., Mutaamba, M., Partanen, J. J., Brumpton, B. M., Chavan, S., Chen, T. T., Daya, M., Ding, Y., Feng, Y. C. A., Gignoux, C. R., Graham, S. E., Hornsby, W. E., Ingold, N., Johnson, R., Laisk, T., Lin, K., Lv, J., Millwood, I. Y., Loos, Ruth, BBJ, B., BioMe, B., BioVU, B., Canadian Partnership for Tomorrow's Health/OHS, C. P. F. T. H., China Kadoorie Biobank Collaborative Group, C. K. B. C. G., Colorado Center for Personalized Medicine, C. C. F. P. M., deCODE Genetics, D. G., ESTBB, E., FinnGen, F., Generation Scotland, G. S., Genes & Health, G. &. H., LifeLines, L., Mass General Brigham Biobank, M. G. B. B., Michigan Genomics Initiative, M. G. I., QIMR Berghofer Biobank, Q. B. B., Taiwan Biobank, T. B., The HUNT Study, T. H. S., UCLA ATLAS Community Health Initiative, U. A. C. H. I. & UKBB, U., 2023, In: Cell Genomics. 3, 1, 18 p., 100241.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Rare variants in long non-coding RNAs are associated with blood lipid levels in the TOPMed whole-genome sequencing study

    Wang, Y., Selvaraj, M. S., Li, X., Li, Z., Holdcraft, J. A., Arnett, D. K., Bis, J. C., Blangero, J., Boerwinkle, E., Bowden, D. W., Cade, B. E., Carlson, J. C., Carson, A. P., Chen, Y. D. I., Curran, J. E., de Vries, P. S., Dutcher, S. K., Ellinor, P. T., Floyd, J. S., Fornage, M. & 31 others, Freedman, B. I., Gabriel, S., Germer, S., Gibbs, R. A., Guo, X., He, J., Heard-Costa, N., Hildalgo, B., Hou, L., Irvin, M. R., Joehanes, R., Kaplan, R. C., Kardia, S. L., Kelly, T. N., Kim, R., Kooperberg, C., Kral, B. G., Levy, D., Li, C., Liu, C., Lloyd-Jone, D., Loos, Ruth, Mahaney, M. C., Martin, L. W., Mathias, R. A., Minster, R. L., Mitchell, B. D., Montasser, M. E., Morrison, A. C., Murabito, J. M. & NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, N. T. F. P. M. (. C., 2023, In: American Journal of Human Genetics. 110, 10, p. 1704-1717 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Distilling causality between physical activity traits and obesity via Mendelian randomization

    Wang, Z., Davey Smith, G., Loos, Ruth & den Hoed, M., 2023, In: Communications Medicine. 3, 6 p., 173.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    The Value of Rare Genetic Variation in the Prediction of Common Obesity in European Ancestry Populations

    Wang, Z., Choi, S. W., Chami, N., Boerwinkle, E., Fornage, M., Redline, S., Bis, J. C., Brody, J. A., Psaty, B. M., Kim, W., McDonald, M. L. N., Regan, E. A., Silverman, E. K., Liu, C. T., Vasan, R. S., Kalyani, R. R., Mathias, R. A., Yanek, L. R., Arnett, D. K., Justice, A. E. & 21 others, North, K. E., Kaplan, R., Heckbert, S., de Andrade, M., Guo, X., Lange, L. A., Rich, S., Rotter, J. I., Ellinor, P. T., Lubitz, S. A., Blangero, J., Shoemaker, M. B., Darbar, D., Gladwin, M. T., Albert, C. M., Chasman, D. I., Jackson, R. D., Kooperberg, C., Reiner, A. P., O’Reilly, P. F. & Loos, Ruth, 2022, In: Frontiers in Endocrinology. 13, 12 p., 863893.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention

    Wang, Z., Emmerich, A., Pillon, N. J., Moore, T., Hemerich, D., Cornelis, M. C., Mazzaferro, E., Broos, S., Ahluwalia, T. S., Bartz, T. M., Bentley, A. R., Bielak, L. F., Chong, M., Chu, A. Y., Berry, D., Dorajoo, R., Dueker, N. D., Kasbohm, E., Feenstra, B., Feitosa, M. F. & 32 others, Gieger, C., Graff, M., Hall, L. M., Haller, T., Hartwig, F. P., Hillis, D. A., Huikari, V., Heard-Costa, N., Holzapfel, C., Jackson, A. U., Johansson, A., Jorgensen, A. M., Kaakinen, M. A., Karlsson, R., Kerr, K. F., Kim, B., Koolhaas, C. M., Kutalik, Z., Pacolet, A., Zhao, J., Balslev-Harder, M. N., Grarup, N., Linneberg, Allan René, Hansen, Torben, Melbye, M., Pedersen, Oluf Borbye, Pers, Tune H, Sørensen, Thorkild I.A., Zierath, Juleen R, Kilpeläinen, Tuomas O., Loos, Ruth & LifeLines Cohort Study, L. C. S., 2022, In: Nature Genetics. 54, p. 1332–1344 25 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    The genetic history of Greenlandic-European contact

    Waples, R. K., Hauptmann, A. L., Seiding, I. H., Jørsboe, E., Jørgensen, M. E., Grarup, N., Andersen, M. K., Larsen, C. V. L., Bjerregaard, P., Hellenthal, G., Hansen, Torben, Albrechtsen, Anders & Moltke, Ida, 2021, In: Current Biology. 31, 10, p. 2214-2219.e4

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Animal models of mucositis: critical tools for advancing pathobiological understanding and identifying therapeutic targets

    Wardill, H. R., Tissing, W. J. E., Kissow, Hannelouise & Stringer, A. M., 2019, In: Current Opinion in Supportive and Palliative Care. 13, 2, p. 119-133

    Research output: Contribution to journal › Review › Research › peer-review

  23. Published

    Maternal and fetal genetic contribution to gestational weight gain

    Warrington, N. M., Richmond, R., Fenstra, B., Myhre, R., Gaillard, R., Paternoster, L., Wang, C. A., Beaumont, R. N., Das, S., Murcia, M., Barton, S. J., Espinosa, A., Thiering, E., Atalay, M., Pitkänen, N., Ntalla, I., Jonsson, A. E., Freathy, R., Karhunen, V., Tiesler, C. M. T. & 44 others, Allard, C., Crawford, A., Ring, S. M., Melbye, M., Magnus, P., Rivadeneira, F., Skotte, L., Hansen, Torben, Marsh, J., Guxens, M., Holloway, J. W., Grallert, H., Jaddoe, V. W. V., Lowe, W. L., Roumeliotaki, T., Hattersley, A. T., Lindi, V., Pahkala, K., Panoutsopoulou, K., Standl, M., Flexeder, C., Bouchard, L., Aagaard Nohr, E., Marina, L. S., Kogevinas, M., Niinikoski, H., Dedoussis, G., Heinrich, J., Reynolds, R. M., Lakka, T., Zeggini, E., Raitakari, O. T., Chatzi, L., Inskip, H. M., Bustamante, M., Hivert, M., Jarvelin, M., Sørensen, Thorkild I.A., Pennell, C., Felix, J. F., Jacobsson, B., Geller, F., Evans, D. M. & Lawlor, D. A., 2018, In: International journal of obesity (2005). 42, p. 775–784

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

    Stokholm, Jakob, Michaelsen, Kim F., Freathy, R. M. & EGG Consortium, E. C., 2019, In: Nature Genetics. 51, 5, p. 804-814

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Physiology insights

    Watanabe, R. M. & Hansen, Torben, 2016, The Genetics of Type 2 Diabetes and Related Traits: Biology, Physiology and Translation. Springer, p. 207-221 15 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

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