Novo Nordisk Foundation Center for Basic Metabolic Research

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  1. Published

    Imputation of label-free quantitative mass spectrometry-based proteomics data using self-supervised deep learning

    Webel, Henry, Niu, Lili, Nielsen, Annelaura Bach, Locard-Paulet, Marie, Mann, Matthias, Jensen, Lars Juhl & Rasmussen, Simon, 2024, In: Nature Communications. 15, 15 p., 5405.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Effects of carbohydrate restriction on body weight and glycemic control in individuals with type 2 diabetes: A randomized controlled trial of efficacy in real-life settings

    Weber, P., Thomsen, M. N., fbg982, fbg982, Samkani, A., Carl, M. H., Astrup, A., Frystyk, J., Holst, Jens Juul, Hartmann, Bolette, Madsbad, Sten, Magkos, Faidon, Krarup, T. & Haugaard, Steen Bendix, 2022, In: Nutrients. 14, 24, 12 p., 5244.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Molecular Connectomics Reveals a Glucagon-Like Peptide 1 Sensitive Neural Circuit for Satiety

    Webster, A. N., Becker, J. J., Li, C., Schwalbe, D. C., Kerspern, D., Karolczak, E. O., Godschall, E. N., Belmont-Rausch, Dylan Matthew, Pers, Tune H, Lutas, A., Habib, N., Güler, A. D., Krashes, M. J. & Campbell, J. N., 2023, bioRxiv, 47 p.

    Research output: Working paper › Preprint › Research

  4. Published

    Global hypomethylation is an independent prognostic factor in diffuse large B cell lymphoma

    Wedge, E., Hansen, Jakob Werner, Garde, C., Asmar, F., Tholstrup, Dorte Maegaard, Kristensen, S. S., Munch-Petersen, H. D., Ralfkiaer, E., Brown, Peter de Nully, Grønbæk, Kirsten & Kristensen, L. S., Jul 2017, In: American Journal of Hematology. 92, 7, p. 689-694 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Comparative genome sequencing and analyses of Mycobacterium cosmeticum reveal potential for biodesulfization of gasoline

    Wee, W. Y., Dutta, A., Jayaraj, J. & Choo, S. W., 2019, In: PLOS ONE. 14, 4, 18 p., e0214663.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    LMNA rs4641 and the muscle lamin A and C isoforms in twins--metabolic implications and transcriptional regulation

    Wegner, L., Anthonsen, S., Bork-Jensen, J., Dalgaard, L., Hansen, Torben, Pedersen, Oluf Borbye, Poulsen, P. & Vaag, Allan, Aug 2010, In: The Journal of clinical endocrinology and metabolism. 95, 8, p. 3884-92 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Impact of TCF7L2 rs7903146 on insulin secretion and action in young and elderly Danish twins.

    Wegner, L., Hussain, M. S., Pilgaard, K., Hansen, T., Pedersen, Oluf Borbye, Vaag, Allan & Poulsen, I. P., 2008, In: Journal of Clinical Endocrinology and Metabolism. 93, 10, p. 4013-9 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Common variation in LMNA increases susceptibility to type 2 diabetes and associates with elevated fasting glycemia and estimates of body fat and height in the general population: studies of 7,495 Danish whites

    Wegner, L., Andersen, G., Sparsø, T., Grarup, N., Glümer, C., Borch-Johnsen, K., Jørgensen, T., Hansen, Torben & Pedersen, Oluf Borbye, 2007, In: Diabetes. 56, 3, p. 694-8 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Closing in on the C. elegans ORFeome by cloning TWINSCAN predictions

    Wei, C., Lamesch, P., Arumugam, Mani, Rosenberg, J., Hu, P., Vidal, M. & Brent, M. R., 2005, In: Genome Research. 15, 4, p. 577-82 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Cannabinoid receptor 1 antagonist genistein attenuates marijuana-induced vascular inflammation

    Wei, T-T., Chandy, M., Nishiga, M., Zhang, A., Kumar, K. K., Thomas, D., Manhas, A., Rhee, S., Justesen, J. M., Chen, I. Y., Wo, H-T., Khanamiri, S., Yang, J. Y., Seidl, F. J., Burns, N. Z., Liu, C., Sayed, N., Shie, J-J., Yeh, C-F., Yang, K-C. & 5 others, Lau, E., Lynch, K. L., Rivas, M., Kobilka, B. K. & Wu, J. C., 2022, In: Cell. 185, 10, p. 1676-1693.e23

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Targeted next-generation sequencing as a comprehensive test for patients with and female carriers of DMD/BMD: a multi-population diagnostic study

    Wei, X., Dai, Y., Yu, P., Qu, N., Lan, Z., Hong, X., Sun, Y., Yang, G., Xie, S., Shi, Q., Zhou, H., Zhu, Q., Chu, Y., Yao, F., Wang, J., He, J., Yang, Y., Liang, Y., Yang, Y., Qi, M. & 8 others, Yang, L., Wang, W., Wu, H., Duan, J., Shen, C., Wang, J., Cui, L. & Yi, X., 2014, In: European Journal of Human Genetics. 22, p. 110-118 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches

    Welsh, J. A., Goberdhan, D. C. I., O’Driscoll, L., Buzas, E. I., Blenkiron, C., Bussolati, B., Cai, H., Di Vizio, D., Driedonks, T. A. P., Erdbrügger, U., Falcon-Perez, J. M., Fu, Q. L., Hill, A. F., Lenassi, M., Lim, S. K., Mahoney, M. Ỹ. G., Mohanty, S., Möller, A., Nieuwland, R., Ochiya, T. & 31 others, Sahoo, S., Torrecilhas, A. C., Zheng, L., Zijlstra, A., Abuelreich, S., Bagabas, R., Bergese, P., Bridges, E. M., Brucale, M., Burger, D., Carney, R. P., Cocucci, E., Crescitelli, R., Hanser, E., Harris, A. L., Haughey, N. J., Benediktsdóttir, B. E., Gargiulo, E., Gori, A., Guo, W., Hufnagel, Antonia Sophie, Di Ianni, E., Jacobsen, Søren, Li, B., Mellergaard, M., Nejsum, P., Nolan, J. P., Østergaard, Ole, Yarani, R., Yin, H. & MISEV Consortium, M. C., 2024, In: Journal of Extracellular Vesicles. 13, 2, 84 p., e12404.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    The brominated flame retardant PBDE 99 promotes adipogenesis via regulating mitotic clonal expansion and PPARγ expression

    Wen, Q., Xie, X., Zhao, C., Ren, Q., Zhang, X., Wei, D., Emanuelli, Brice & Du, Y., 2019, In: The Science of the Total Environment. 670, p. 67-77 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Cross-Validation of a Glucose-Insulin-Glucagon Pharmacodynamics Model for Simulation Using Data From Patients With Type 1 Diabetes

    Wendt, S. L., Ranjan, A., Møller, J. K., Schmidt, S., Knudsen, C. B., Holst, Jens Juul, Madsbad, Sten, Madsen, H., Nørgaard, Kirsten & Jørgensen, J. B., 1 Nov 2017, In: Journal of Diabetes Science and Technology. 11, 6, p. 1101-1111 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Genetic Determinants of Electrocardiographic P-Wave Duration and Relation to Atrial Fibrillation

    Weng, L. C., Hall, A. W., Choi, S. H., Jurgens, S. J., Haessler, J., Bihlmeyer, N. A., Grarup, N., Lin, H., Teumer, A., Li-Gao, R., Yao, J., Guo, X., Brody, J. A., Müller-Nurasyid, M., Schramm, K., Verweij, N., van den Berg, M. E., van Setten, J., Isaacs, A., Ramírez, J. & 40 others, Warren, H. R., Padmanabhan, S., Kors, J. A., de Boer, R. A., van der Meer, P., Sinner, M. F., Waldenberger, M., Psaty, B. M., Taylor, K. D., Völker, U., Kanters, Jørgen K., Li, M., Alonso, A., Perez, M. V., Vaartjes, I., Bots, M. L., Huang, P. L., Heckbert, S. R., Lin, H. J., Kornej, J., Munroe, P. B., van Duijn, C. M., Asselbergs, F. W., Stricker, B. H., van der Harst, P., Kääb, S., Peters, A., Sotoodehnia, N., Rotter, J. I., Mook-Kanamori, D. O., Dörr, M., Felix, S. B., Linneberg, Allan René, Hansen, Torben, Arking, D. E., Kooperberg, C., Benjamin, E. J., Lunetta, K. L., Ellinor, P. T. & Lubitz, S. A., 2020, In: Circulation. Genomic and precision medicine. 13, 5, p. 387-395 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Meta-Analysis of Genome-Wide Association Studies Reveals Genetic Mechanisms of Supraventricular Arrhythmias

    Weng, L. C., Khurshid, S., Hall, A. W., Nauffal, V., Morrill, V. N., Sun, Y. V., Rämö, J. T., Beer, D., Lee, S., Nadkarni, G., Johnson, R., Andreasen, L., Clayton, A., Pullinger, C. R., Yoneda, Z. T., Friedman, D. J., Hyman, M. C., Judy, R. L., Skanes, A. C., Orland, K. M. & 39 others, Jordà, P., Treu, T. M., Oetjens, M. T., Subbiah, R., Hartmann, J. P., May, H. T., Kane, J. P., Issa, T. Z., Nafissi, N. A., Leong-Sit, P., Dubé, M. P., Roselli, C., Choi, S. H., Tardif, J. C., Khan, H. R., Knight, S., Svendsen, Jesper Hastrup, Walker, B., Linnér, R. K., Gaziano, J. M., Tadros, R., Fatkin, D., Rader, D. J., Shah, S. H., Roden, D. M., Marcus, G. M., Loos, Ruth, Damrauer, S. M., Haggerty, C. M., Cho, K., Palotie, A., Olesen, Morten Steen Salling, Eckhardt, L. L., Roberts, J. D., Cutler, M. J., Shoemaker, M. B., Wilson, P. W. F., Ellinor, P. T. & Lubitz, S. A., 2024, In: Circulation: Genomic and Precision Medicine. 17, 3, e004320.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Mutation analysis of the MCHR1 gene in human obesity

    Wermter, A-K., Reichwald, K., Büch, T., Geller, F., Platzer, C., Huse, K., Hess, C., Remschmidt, H., Gudermann, T., Preibisch, G., Siegfried, W., Goldschmidt, H-P., Li, W-D., Price, R. A., Biebermann, H., Krude, H., Vollmert, C., Wichmann, H-E., Illig, T., Sørensen, T. I. A. & 11 others, Astrup, A., Larsen, L. H., Pedersen, Oluf Borbye, Eberlé, D., Clément, K., Blundell, J., Wabitsch, M., Schäfer, H., Platzer, M., Hinney, A. & Hebebrand, J., 2005, In: European Journal of Endocrinology. 152, 6, p. 851-62 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Four groups of type 2 diabetes contribute to the etiological and clinical heterogeneity in newly diagnosed individuals: An IMI DIRECT study

    Wesolowska-Andersen, A., Brorsson, C. A., Bizzotto, R., Mari, A., Tura, A., Koivula, R., Mahajan, A., Vinuela, A., Tajes, J. F., Sharma, S., Haid, M., Prehn, C., Artati, A., Hong, M. G., Musholt, P. B., Kurbasic, A., Masi, F. D., Tsirigos, K., Pedersen, H. K., Gudmundsdottir, V. & 31 others, Thomas, Cecilia Engel, Banasik, Karina, Jennison, C., Jones, A., Kennedy, G., Bell, J., Thomas, L., Frost, G., Thomsen, H., Allin, K., Hansen, T. H., drb459, drb459, Hansen, Torben, Rutters, F., Elders, P., t'Hart, L., Bonnefond, A., Canouil, M., Brage, S., Kokkola, T., Heggie, A., McEvoy, D., Hattersley, A., McDonald, T., Teare, H., Ridderstrale, M., Walker, M., Forgie, I., Pedersen, Oluf Borbye, Brunak, Søren & IMI-DIRECT consortium, I. C., 2022, In: Cell Reports Medicine. 3, 1, 25 p., 100477.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility

    Wessel, J., Chu, A. Y., Willems, S. M., Wang, S., Yaghootkar, H., Brody, J. A., Dauriz, M., Hivert, M-F., Raghavan, S., Lipovich, L., Hidalgo, B., Fox, K., Huffman, J. E., An, P., Lu, Y., Rasmussen-Torvik, L. J., Grarup, N., Ehm, M. G., Li, L., Baldridge, A. S. & 31 others, Stančáková, A., Abrol, R., Besse, C., Boland, A., Bork-Jensen, J., Fornage, M., Freitag, D. F., Garcia, M. E., Guo, X., Hara, K., Isaacs, A., Jakobsdottir, J., Lange, L. A., Layton, J. C., Li, M., Hua Zhao, J., Meidtner, K., Morrison, A. C., Nalls, M. A., Peters, M. J., Sabater-Lleal, M., Schurmann, C., Silveira, A., Smith, A. V., Southam, L., Allin, K. H., Jørgensen, T., Linneberg, Allan René, Hansen, Torben, Pedersen, Oluf Borbye & EPIC-InterAct Consortium, E. C., 29 Jan 2015, In: Nature Communications. 6, p. 5897

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Differential impact of glucose administered intravenously or orally on bone turnover markers in healthy male subjects

    Westberg-Rasmussen, S., Starup-Linde, J., Hermansen, K., Holst, Jens Juul, Hartmann, Bolette, Vestergaard, P. & Gregersen, S., Apr 2017, In: Bone. 97, p. 261-266 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Pregnancy-Associated Bleeding and Genetics: Five Sequence Variants in the Myometrium and Progesterone Signaling Pathway are associated with postpartum hemorrhage

    Westergaard, D., Steinthorsdottir, V., Stefansdottir, L., Rohde, P. D., Wu, X., Geller, F., Tyrmi, J., Havulinna, A. S., Navais, P. S., Flatley, C., Ostrowski, S. R., Pedersen, O. B., Erikstrup, C., Sørensen, E., Mikkelsen, C., Brun, M. T., Jensen, B. A., Brodersen, T., Ullum, H., Magnus, P. & 8 others, Andreassen, O. A., Njolstad, P. R., Krebs, Lone, Hansen, Thomas Folkmann, Banasik, Karina, Brunak, Søren, Nielsen, Henriette Svarre & FinnGen, F., 2023, medRxiv, 51 p. (medRxiv).

    Research output: Working paper › Preprint › Research

  22. Published

    Glucagon-like peptide-1 7-36 amide and peptide YY from the L-cell of the ileal mucosa are potent inhibitors of vagally induced gastric acid secretion in man

    Wettergren, A., Petersen, H., Ørskov, Cathrine, Christiansen, J., Sheikh, S. P. & Holst, Jens Juul, Jun 1994, In: Scandinavian Journal of Gastroenterology. 29, 6, p. 501-5 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Truncated GLP-1 (proglucagon 78-107-amide) inhibits gastric and pancreatic functions in man

    Wettergren, A., Schjoldager, B., Mortensen, P. E., Myhre, J., Christiansen, J. & Holst, Jens Juul, 1993, In: Digestive Diseases and Sciences. Vol. 38, no. 4, p. 665-673

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Glucagon-like peptide-1 (GLP-1) 7-36 amide and peptide YY from L-cell in the ileal mucosa are potent inhibitors of vagally induced gastric acid secretion in man

    Wettergren, A., Petersen, H., Ørskov, Cathrine, Christiansen, J., Sheikh, S. & Holst, Jens Juul, 1994, In: Scandinavian Journal of Gastroenterology. 29, p. 501-505

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Associations between ghrelin and leptin and neural food cue reactivity in a fasted and sated state

    Wever, M. C. M., van Meer, F., Charbonnier, L., Crabtree, D. R., Buosi, W., Giannopoulou, A., Androutsos, O., Johnstone, A. M., Manios, Y., Meek, C. L., Holst, Jens Juul, Smeets, P. A. M. & Full4Health consortium, F. C., 2021, In: NeuroImage. 240, 11 p., 118374.

    Research output: Contribution to journal › Journal article › Research › peer-review

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