Novo Nordisk Foundation Center for Basic Metabolic Research

  1. Published

    In the rat pancreas, somatostatin tonically inhibits glucagon secretion and is required for glucose-induced inhibition of glucagon secretion

    Xu, S. F. S., Andersen, Daniel Bjørklund, Izarzugaza, J. M. G., Kuhre, Rune Ehrenreich & Holst, Jens Juul, 2020, In: Acta Physiologica. 229, 3, 15 p., e13464.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Resequencing 50 accessions of cultivated and wild rice yields markers for identifying agronomically important genes

    Xu, X., Liu, X., Ge, S., Jensen, J. D., Hu, F., Li, X., Dong, Y., Gutenkunst, R. N., Fang, L., Huang, L., Li, J., He, W., Zhang, G., Zheng, X., Zhang, F., Li, Y., Yu, C., Kristiansen, K., Zhang, X., Wang, J. & 5 others, Wright, M., McCouch, S., Nielsen, Rasmus, Wang, J. & Wang, W., 2012, In: Nature Biotechnology. 30, 1, p. 105-111 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Single-cell exome sequencing reveals single-nucleotide mutation characteristics of a kidney tumor: Cell

    Xu, X., Hou, Y., Yin, X., Bao, L., Tang, A., Song, L., Li, F., Tsang, S., Wu, K., Wu, H., He, W., Zeng, L., Xing, M., Wu, R., Jiang, H., Liu, X., Cao, D., Guo, G., Hu, X., Gui, Y. & 19 others, Li, Z., Xie, W., Sun, X., Shi, M., Cai, Z., Wang, B., Zhong, M., Li, J., Lu, Z., Gu, N., Zhang, X., Goodman, L., Bolund, L., Wang, J., Yang, H., Kristiansen, Karsten, Dean, M., Li, Y. & Wang, J., 2012, In: Cell. 148, 5, p. 886-895 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Embryo genome profiling by single-cell sequencing for preimplantation genetic diagnosis in a β-thalassemia family

    Xu, Y., Chen, S., Yin, X., Shen, X., Pan, X., Chen, F., Jiang, H., Liang, Y., Wang, W., Xu, X., Wang, J., Zhang, X., Zhou, C. & Wang, J., 2015, In: Clinical Chemistry. 61, 4, p. 617-626 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Early phase glucagon and insulin secretory abnormalities, but not incretin secretion, are similarly responsible for hyperglycemia after ingestion of nutrients

    Yabe, D., Kuroe, A., Watanabe, K., Iwasaki, M., Hamasaki, A., Hamamoto, Y., Harada, N., Yamane, S., Lee, S., Murotani, K., Deacon, Carolyn F., Holst, Jens Juul, Hirano, T., Inagaki, N., Kurose, T. & Seino, Y., 2015, In: Journal of Diabetes and its Complications. 29, p. 413-421 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Mendelian Randomisation Studies Do Not Support a Causal Role for Reduced Circulating Adiponectin Levels in Insulin Resistance and Type 2 Diabetes

    Yaghootkar, H., Lamina, C., Scott, R. A., Dastani, Z., Hivert, M-F., Warren, L. L., Stancáková, A., Buxbaum, S. G., Lyytikäinen, L-P., Henneman, P., Wu, Y., Cheung, C. Y., Pankow, J. S., Jackson, A. U., Gustafsson, S., Zhao, J. H., Ballantyne, C. M., Xie, W., Bergman, R. N., Boehnke, M. & 31 others, El Bouazzaoui, F., Collins, F. S., Dunn, S. H., Dupuis, J., Forouhi, N. G., Gillson, C., Hattersley, A. T., Hong, J., Kähönen, M., Kuusisto, J., Kedenko, L., Kronenberg, F., Doria, A., Assimes, T. L., Ferrannini, E., Hansen, Torben, Hao, K., Häring, H., Knowles, J. W., Lindgren, C. M., Nolan, J. J., Paananen, J., Pedersen, Oluf Borbye, Quertermous, T., Smith, U., Lehtimäki, T., Liu, C., Loos, R. J., McCarthy, M. I., Morris, A. D. & the GENESIS consortium, T. G. C., 8 Jul 2013, In: Diabetes. 62, 10, p. 3589 3598 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Association analysis of 29,956 individuals confirms that a low-frequency variant at CCND2 halves the risk of type 2 diabetes by enhancing insulin secretion

    Yaghootkar, H., Stancáková, A., Freathy, R. M., Vangipurapu, J., Weedon, M. N., Xie, W., Wood, A. R., Ferrannini, E., Mari, A., Ring, S. M., Lawlor, D. A., Davey Smith, G., Jørgensen, T., Hansen, T., Pedersen, O., Steinthorsdottir, V., Guðbjartsson, D. F., Thorleifsson, G., Thorsteinsdottir, U., Stefansson, K. & 7 others, Hattersley, A. T., Walker, M., Morris, A. D., McCarthy, M. I., Palmer, C. N. A., Laakso, M. & Frayling, T. M., Jun 2015, In: Diabetes. 64, 6, p. 2279-85 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Genetic Studies of Leptin Concentrations Implicate Leptin in the Regulation of Early Adiposity

    Yaghootkar, H., Zhang, Y., Spracklen, C. N., Karaderi, T., Huang, L. O., Bradfield, J., Schurmann, C., Fine, R. S., Preuss, M. H., Kutalik, Z., Wittemans, L. B., Lu, Y., Metz, S., Willems, S. M., Li-Gao, R., Grarup, N., Wang, S., Molnos, S., Sandoval-Zárate, A. A., Nalls, M. A. & 32 others, Lange, L. A., Haesser, J., Guo, X., Lyytikäinen, L., Feitosa, M. F., Sitlani, C. M., Venturini, C., Mahajan, A., Kacprowski, T., Wang, C. A., Chasman, D. I., Amin, N., Broer, L., Robertson, N., Young, K. L., Allison, M., Auer, P. L., Blüher, M., Borja, J. B., Bork-Jensen, J., Carrasquilla, Germán D., Christofidou, P., Demirkan, A., Doege, C. A., Jakupovic, Hermina, Li, J., Lind, L., Kovacs, P., Hansen, Torben, Loos, R. J., Kilpeläinen, Tuomas O. & Leptin Exomechip Collaboration, L. E. C., 2020, In: Diabetes. 69, 11, 93 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Prediabetes Defined by First Measured HbA1c Predicts Higher Cardiovascular Risk Compared With HbA1c in the Diabetes Range: A Cohort Study of Nationwide Registries

    Yahyavi, S. K., Snorgaard, O., Knop, Filip Krag, Schou, Morten, Lee, C., Selmer, C., Gislason, Gunnar Hilmar, Torp-Pedersen, Christian, Blomberg Jensen, M. & Nissen Bonde, A., 2021, In: Diabetes Care. 44, 12, p. 2767-2774 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    A genome-wide association study in the Japanese population identifies susceptibility loci for type 2 diabetes at UBE2E2 and C2CD4A-C2CD4B

    Yamauchi, T., Hara, K., Maeda, S., Yasuda, K., Takahashi, A., Horikoshi, M., Nakamura, M., Fujita, H., Grarup, N., Cauchi, S., Ng, D. P. K., Ma, R. C. W., Tsunoda, T., Kubo, M., Watada, H., Maegawa, H., Okada-Iwabu, M., Iwabu, M., Shojima, N., Shin, H. D. & 26 others, Andersen, G., Witte, D. R., Jørgensen, T., Lauritzen, T., Sandbæk, A., Hansen, T., Ohshige, T., Omori, S., Saito, I., Kaku, K., Hirose, H., So, W., Beury, D., Chan, J. C. N., Park, K. S., Tai, E. S., Ito, C., Tanaka, Y., Kashiwagi, A., Kawamori, R., Kasuga, M., Froguel, P., Pedersen, Oluf Borbye, Kamatani, N., Nakamura, Y. & Kadowaki, T., 1 Oct 2010, In: Nature Genetics. 42, 10, p. 864-8 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques

    Yan, G., Zhang, G., Fang, X., Zhang, Y., Li, C., Ling, F., Cooper, D. N., Li, Q., Li, Y., van Gool, A. J., Du, H., Chen, J., Chen, R., Zhang, P., Huang, Z., Thompson, J. R., Meng, Y., Bai, Y., Wang, J., Zhuo, M. & 26 others, Wang, T., Huang, Y., Wei, L., Li, J., Wang, Z., Hu, H., Yang, P., Le, L., Stenson, P. D., Li, B., Liu, X., Ball, E. V., An, N., Huang, Q., Zhang, Y., Fan, W., Zhang, X., Li, Y., Wang, W., Katze, M. G., Su, B., Nielsen, Rasmus, Yang, H., Wang, J., Wang, X. & Wang, J., 2011, In: Nature Biotechnology. 29, 11, p. 1019-1023 5 p.

    Research output: Contribution to journalLetterResearchpeer-review

  12. Published

    Evidence for non-CpG methylation in mammals

    Yan, J., Zierath, Juleen R & Barrès, Romain, 1 Nov 2011, In: Experimental Cell Research. 317, 18, p. 2555-61 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Effect of three types of additives in poor solvent on preparation of sustained-release nitrendipine microspheres by the quasi-emulsion solvent diffusion method

    Yang, Mingshi, Cui, F., Fan, Yong, You, B., Ren, K., Feng, H. & Kawashima, Y., 1 Mar 2005, In: Journal of Drug Delivery Science and Technology. 15, 2, p. 129-135 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Molecular genetic overlap between migraine and major depressive disorder

    Yang, Y., Zhao, H., Boomsma, D. I., Ligthart, L., Belin, A. C., Smith, G. D., Esko, T., Freilinger, T. M., Hansen, T. F., Ikram, M. A., Kallela, M., Kubisch, C., Paraskevi, C., Strachan, D. P., Wessman, M., Gormley, P., Anttila, V., Winsvold, B. S., Palta, P., Esko, T. & 30 others, Pers, Tune H, Farh, K. H., Cuenca-Leon, E., Muona, M., Furlotte, N. A., Kurth, T., Ingason, A., McMahon, G., Ligthart, L., Terwindt, G. M., Kallela, M., Freilinger, T. M., Ran, C., Gordon, S. G., Stam, A. H., Steinberg, S., Borck, G., Koiranen, M., Quaye, L., Adams, H. H. H., Lehtimäki, T., Sarin, A. P., Wedenoja, J., Hinds, D. A., Buring, J. E., Schürks, M., Christensen, A. F., Hansen, Thomas Folkmann, Werge, Thomas & Olesen, Jes, 2018, In: European Journal of Human Genetics. 26, 8, p. 1202-1216 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Spatial consequences of bridging the saccadic gap

    Yarrow, K., Whiteley, Louise, Rothwell, J. C. & Haggard, P., 2006, In: Vision Research. 46, 4, p. 545-55 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Biases in the perceived timing of perisaccadic perceptual and motor events

    Yarrow, K., Whiteley, Louise, Haggard, P. & Rothwell, J. C., 2006, In: Attention, Perception & Psychophysics. 68, 7, p. 1217-26 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Cytoglobin affects tumorigenesis and the expression of ulcerative colitis-associated genes under chemically induced colitis in mice

    Yassin, M., Kissow, Hannelouise, Vainer, B., Joseph, P. D., Hay-Schmidt, Anders, Olsen, J. & Pedersen, Anders Elm, 2018, In: Scientific Reports. 8, p. 1-16 6905.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Rectal insulin instillation inhibits inflammation and tumor development in chemically-induced colitis

    Yassin, M., Sadowska, Z., Tritsaris, Katerina, Kissow, Hannelouise, Hansen, Camilla Hartmann Friis, Forman, Julie Lyng, Rogler, G., Troelsen, J. T., Pedersen, Anders Elm & Olsen, Jørgen, 2018, In: Journal of Crohn's and Colitis. 12, 12, p. 1459–1474 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus

    Yasuda, K., Miyake, K., Horikawa, Y., Hara, K., Osawa, H., Furuta, H., Hirota, Y., Mori, H., Jonsson, A. E., Sato, Y., Yamagata, K., Hinokio, Y., Wang, H-Y., Tanahashi, T., Nakamura, N., Oka, Y., Iwasaki, N., Iwamoto, Y., Yamada, Y., Seino, Y. & 27 others, Maegawa, H., Kashiwagi, A., Takeda, J., Maeda, E., Shin, H. D., Cho, Y. M., Park, K. S., Lee, H. K., Ng, M. C. Y., Ma, R. C. W., So, W., Chan, J. C. N., Lyssenko, V., Tuomi, T., Nilsson, P., Groop, L., Kamatani, N., Sekine, A., Nakamura, Y., Yamamoto, K., Yoshida, T., Tokunaga, K., Itakura, M., Makino, H., Nanjo, K., Kadowaki, T. & Kasuga, M., Sep 2008, In: Nature Genetics. 40, 9, p. 1092-7 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    A saturated map of common genetic variants associated with human height

    Yengo, L., Vedantam, S., Marouli, E., Sidorenko, J., Bartell, E., Sakaue, S., Graff, M., Eliasen, A. U., Jiang, Y., Raghavan, S., Miao, J., Arias, J. D., Graham, S. E., Mukamel, R. E., Spracklen, C. N., Yin, X., Chen, S-H., Ferreira, T., Highland, H. H., Ji, Y. & 37 others, Karaderi, Tugce, Lin, K., Lull, K., Malden, D. E., Lepola, Mette Andersen, Appadurai, V., Bork-Jensen, J., Burgdorf, Kristoffer Sølvsten, Hansen, Thomas Folkmann, Jonsson, Anna Elisabet, Jorgensen, T., Liu, J., Møllehave, Line Tang, Smit, Roelof Adriaan Johan, Zhao, J., Bisgaard, H., Bønnelykke, Klaus, Dantoft, T. M., Grarup, N., Hansen, Torben, Jackson, R. D., Karpe, F., Kovacs, P., Lind, L., Linneberg, Allan René, Pedersen, Oluf Borbye, Werge, Thomas, Sun, Y., Loos, Ruth, Winkler, T. W., 23andMe Res Team, 2. R. T., VA Million Vet Program, V. M. V. P., DiscovEHR DiscovEHR MyCode Communi, D. D. M. C., eEMERGE Elect Med Records Genomics, E. E. M. R. G., LifeLines Cohort Study, L. C. S., PRACTICAL consortium, P. C. & Understanding Soc Sci Grp, U. S. S. G., 2022, In: Nature. 610, p. 704–712

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Preserved glucagon-like peptide-1 responses to oral glucose, but reduced incretin effect, insulin secretion and sensitivity in young Asians with type 2 diabetes mellitus

    Yeow, T. P., Pacini, G., Tura, A., Hor, C. P., Lim, S. L., Tan, F. H. S., Tong, C. V., Hong, J. Y. H., Md Zain, F., Holst, Jens Juul & Wan Mohamud, W. N., 2017, In: BMJ open diabetes research & care. 5, 1, 9 p., e000352.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Minimum information about a marker gene sequence (MIMARKS) and minimum information about any (x) sequence (MIxS) specifications

    Yilmaz, P., Kottmann, R., Field, D., Knight, R., Cole, J. R., Amaral-Zettler, L., Gilbert, J. A., Karsch-Mizrachi, I., Johnston, A., Cochrane, G., Vaughan, R., Hunter, C., Park, J., Morrison, N., Rocca-Serra, P., Sterk, P., Arumugam, M., Bailey, M., Baumgartner, L., Birren, B. W. & 78 others, Blaser, M. J., Bonazzi, V., Booth, T., Bork, P., Bushman, F. D., Buttigieg, P. L., Chain, P. S. G., Charlson, E., Costello, E. K., Huot-Creasy, H., Dawyndt, P., DeSantis, T., Fierer, N., Fuhrman, J. A., Gallery, R. E., Gevers, D., Gibbs, R. A., San Gil, I., Gonzalez, A., Gordon, J. I., Guralnick, R., Hankeln, W., Highlander, S., Hugenholtz, P., Jansson, J., Kau, A. L., Kelley, S. T., Kennedy, J., Knights, D., Koren, O., Kuczynski, J., Kyrpides, N., Larsen, R., Lauber, C. L., Legg, T., Ley, R. E., Lozupone, C. A., Ludwig, W., Lyons, D., Maguire, E., Methé, B. A., Meyer, F., Muegge, B., Nakielny, S., Nelson, K. E., Nemergut, D., Neufeld, J. D., Newbold, L. K., Oliver, A. E., Pace, N. R., Palanisamy, G., Peplies, J., Petrosino, J., Proctor, L., Pruesse, E., Quast, C., Raes, J., Ratnasingham, S., Ravel, J., Relman, D. A., Assunta-Sansone, S., Schloss, P. D., Schriml, L., Sinha, R., Smith, M. I., Sodergren, E., Spo, A., Stombaugh, J., Tiedje, J. M., Ward, D. V., Weinstock, G. M., Wendel, D., White, O., Whiteley, A., Wilke, A., Wortman, J. R., Yatsunenko, T. & Glöckner, F. O., 2011, In: Nature Biotechnology. 29, 5, p. 415-20 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Genetic and environmental factors affecting birth size variation: a pooled individual-based analysis of secular trends and global geographical differences using 26 twin cohorts

    Yokoyama, Y., Jelenkovic, A., Hur, Y-M., Sund, R., Fagnani, C., Stazi, M. A., Brescianini, S., Ji, F., Ning, F., Pang, Z., Knafo-Noam, A., Mankuta, D., Abramson, L., Rebato, E., Hopper, J. L., Cutler, T. L., Saudino, K. J., Nelson, T. L., Whitfield, K. E., Corley, R. P. & 40 others, Huibregtse, B. M., Derom, C. A., Vlietinck, R. F., Loos, Ruth, Llewellyn, C. H., Fisher, A., Bjerregaard-Andersen, M., Beck-Nielsen, H., Sodemann, M., Krueger, R. F., McGue, M., Pahlen, S., Bartels, M., van Beijsterveldt, C. E. M., Willemsen, G., Harris, J. R., Brandt, I., Nilsen, T. S., Craig, J. M., Saffery, R., Dubois, L., Boivin, M., Brendgen, M., Dionne, G., Vitaro, F., Haworth, C. M. A., Plomin, R., Bayasgalan, G., Narandalai, D., Rasmussen, F., Tynelius, P., Tarnoki, A. D., Tarnoki, D. L., Ooki, S., Rose, R. J., Pietilainen, K. H., Sørensen, Thorkild I.A., Boomsma, D. I., Kaprio, J. & Silventoinen, K., 2018, In: International Journal of Epidemiology. 47, 4, p. 1195-1206 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Twin's Birth-Order Differences in Height and Body Mass Index From Birth to Old Age: A Pooled Study of 26 Twin Cohorts Participating in the CODATwins Project

    Yokoyama, Y., Jelenkovic, A., Sund, R., Sung, J., Hopper, J. L., Ooki, S., Heikkilä, K., Aaltonen, S., Tarnoki, A. D., Tarnoki, D. L., Willemsen, G., Bartels, M., van Beijsterveldt, T. C. E. M., Saudino, K. J., Cutler, T. L., Nelson, T. L., Whitfield, K. E., Wardle, J., Llewellyn, C. H., Fisher, A. & 48 others, He, M., Ding, X., Bjerregaard-Andersen, M., Beck-Nielsen, H., Sodemann, M., Song, Y., Yang, S., Lee, K., Jeong, H., Knafo-Noam, A., Mankuta, D., Abramson, L., Burt, S. A., Klump, K. L., Ordoñana, J. R., Sánchez-Romera, J. F., Colodro-Conde, L., Harris, J. R., Brandt, I., Nilsen, T. S., Craig, J. M., Saffery, R., Ji, F., Ning, F., Pang, Z., Dubois, L., Boivin, M., Brendgen, M., Dionne, G., Vitaro, F., Martin, N. G., Medland, S. E., Montgomery, G. W., Magnusson, P. K. E., Pedersen, N. L., Aslan, A. K. D., Tynelius, P., Haworth, C. M. A., Plomin, R., Rebato, E., Rose, R. J., Goldberg, J. H., Rasmussen, F., Hur, Y., Sørensen, Thorkild I.A., Boomsma, D. I., Kaprio, J. & Silventoinen, K., 2016, In: Twin Research and Human Genetics. 19, 2, p. 112-24 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Postmortem Brains from Subjects with Diabetes Mellitus Display Reduced GLUT4 Expression and Soma Area in Hippocampal Neurons: Potential Involvement of Inflammation

    Yonamine, Caio Yogi, Passarelli, M., Suemoto, C. K., Pasqualucci, C. A., Jacob-Filho, W., Alves, V. A. F., Marie, S. K. N., Correa-Giannella, M. L., Britto, L. R. & Machado, U. F., 2023, In: Cells. 12, 9, 21 p., 1250.

    Research output: Contribution to journalJournal articleResearchpeer-review