Novo Nordisk Foundation Center for Basic Metabolic Research

  1. Published

    Global Biobank analyses provide lessons for developing polygenic risk scores across diverse cohorts

    Wang, Y., Namba, S., Lopera-Maya, E. A., Kerminen, S., Tsuo, K., Läll, K., Kanai, M., Zhou, W., Wu, K. H. H., Favé, M. J., Bhatta, L., Awadalla, P., Brumpton, B. M., Deelen, P., Hveem, K., Lo Faro, V., Mägi, R., Murakami, Y., Sanna, S., Smoller, J. W. & 49 others, Uzunovic, J., Wolford, B. N., Wu, K. H. H., Rasheed, H., Hirbo, J. B., Bhattacharya, A., Zhao, H., Surakka, I., Lopera-Maya, E. A., Chapman, S. B., Karjalainen, J., Kurki, M., Mutaamba, M., Partanen, J. J., Brumpton, B. M., Chavan, S., Chen, T. T., Daya, M., Ding, Y., Feng, Y. C. A., Gignoux, C. R., Graham, S. E., Hornsby, W. E., Ingold, N., Johnson, R., Laisk, T., Lin, K., Lv, J., Millwood, I. Y., Loos, Ruth, BBJ, B., BioMe, B., BioVU, B., Canadian Partnership for Tomorrow's Health/OHS, C. P. F. T. H., China Kadoorie Biobank Collaborative Group, C. K. B. C. G., Colorado Center for Personalized Medicine, C. C. F. P. M., deCODE Genetics, D. G., ESTBB, E., FinnGen, F., Generation Scotland, G. S., Genes & Health, G. &. H., LifeLines, L., Mass General Brigham Biobank, M. G. B. B., Michigan Genomics Initiative, M. G. I., QIMR Berghofer Biobank, Q. B. B., Taiwan Biobank, T. B., The HUNT Study, T. H. S., UCLA ATLAS Community Health Initiative, U. A. C. H. I. & UKBB, U., 2023, In: Cell Genomics. 3, 1, 18 p., 100241.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Rare variants in long non-coding RNAs are associated with blood lipid levels in the TOPMed whole-genome sequencing study

    Wang, Y., Selvaraj, M. S., Li, X., Li, Z., Holdcraft, J. A., Arnett, D. K., Bis, J. C., Blangero, J., Boerwinkle, E., Bowden, D. W., Cade, B. E., Carlson, J. C., Carson, A. P., Chen, Y. D. I., Curran, J. E., de Vries, P. S., Dutcher, S. K., Ellinor, P. T., Floyd, J. S., Fornage, M. & 31 others, Freedman, B. I., Gabriel, S., Germer, S., Gibbs, R. A., Guo, X., He, J., Heard-Costa, N., Hildalgo, B., Hou, L., Irvin, M. R., Joehanes, R., Kaplan, R. C., Kardia, S. L., Kelly, T. N., Kim, R., Kooperberg, C., Kral, B. G., Levy, D., Li, C., Liu, C., Lloyd-Jone, D., Loos, Ruth, Mahaney, M. C., Martin, L. W., Mathias, R. A., Minster, R. L., Mitchell, B. D., Montasser, M. E., Morrison, A. C., Murabito, J. M. & NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, N. T. F. P. M. (. C., 2023, In: American Journal of Human Genetics. 110, 10, p. 1704-1717 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Distilling causality between physical activity traits and obesity via Mendelian randomization

    Wang, Z., Davey Smith, G., Loos, Ruth & den Hoed, M., 2023, In: Communications Medicine. 3, 6 p., 173.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    The Value of Rare Genetic Variation in the Prediction of Common Obesity in European Ancestry Populations

    Wang, Z., Choi, S. W., Chami, N., Boerwinkle, E., Fornage, M., Redline, S., Bis, J. C., Brody, J. A., Psaty, B. M., Kim, W., McDonald, M. L. N., Regan, E. A., Silverman, E. K., Liu, C. T., Vasan, R. S., Kalyani, R. R., Mathias, R. A., Yanek, L. R., Arnett, D. K., Justice, A. E. & 21 others, North, K. E., Kaplan, R., Heckbert, S., de Andrade, M., Guo, X., Lange, L. A., Rich, S., Rotter, J. I., Ellinor, P. T., Lubitz, S. A., Blangero, J., Shoemaker, M. B., Darbar, D., Gladwin, M. T., Albert, C. M., Chasman, D. I., Jackson, R. D., Kooperberg, C., Reiner, A. P., O’Reilly, P. F. & Loos, Ruth, 2022, In: Frontiers in Endocrinology. 13, 12 p., 863893.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention

    Wang, Z., Emmerich, A., Pillon, N. J., Moore, T., Hemerich, D., Cornelis, M. C., Mazzaferro, E., Broos, S., Ahluwalia, T. S., Bartz, T. M., Bentley, A. R., Bielak, L. F., Chong, M., Chu, A. Y., Berry, D., Dorajoo, R., Dueker, N. D., Kasbohm, E., Feenstra, B., Feitosa, M. F. & 32 others, Gieger, C., Graff, M., Hall, L. M., Haller, T., Hartwig, F. P., Hillis, D. A., Huikari, V., Heard-Costa, N., Holzapfel, C., Jackson, A. U., Johansson, A., Jorgensen, A. M., Kaakinen, M. A., Karlsson, R., Kerr, K. F., Kim, B., Koolhaas, C. M., Kutalik, Z., Pacolet, A., Zhao, J., Balslev-Harder, M. N., Grarup, N., Linneberg, Allan René, Hansen, Torben, Melbye, M., Pedersen, Oluf Borbye, Pers, Tune H, Sørensen, Thorkild I.A., Zierath, Juleen R, Kilpeläinen, Tuomas O., Loos, Ruth & LifeLines Cohort Study, L. C. S., 2022, In: Nature Genetics. 54, p. 1332–1344 25 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    The genetic history of Greenlandic-European contact

    Waples, R. K., Hauptmann, A. L., Seiding, I. H., Jørsboe, E., Jørgensen, M. E., Grarup, N., Andersen, M. K., Larsen, C. V. L., Bjerregaard, P., Hellenthal, G., Hansen, Torben, Albrechtsen, Anders & Moltke, Ida, 2021, In: Current Biology. 31, 10, p. 2214-2219.e4

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Animal models of mucositis: critical tools for advancing pathobiological understanding and identifying therapeutic targets

    Wardill, H. R., Tissing, W. J. E., Kissow, Hannelouise & Stringer, A. M., 2019, In: Current Opinion in Supportive and Palliative Care. 13, 2, p. 119-133

    Research output: Contribution to journalReviewResearchpeer-review

  8. Published

    Maternal and fetal genetic contribution to gestational weight gain

    Warrington, N. M., Richmond, R., Fenstra, B., Myhre, R., Gaillard, R., Paternoster, L., Wang, C. A., Beaumont, R. N., Das, S., Murcia, M., Barton, S. J., Espinosa, A., Thiering, E., Atalay, M., Pitkänen, N., Ntalla, I., Jonsson, A. E., Freathy, R., Karhunen, V., Tiesler, C. M. T. & 44 others, Allard, C., Crawford, A., Ring, S. M., Melbye, M., Magnus, P., Rivadeneira, F., Skotte, L., Hansen, Torben, Marsh, J., Guxens, M., Holloway, J. W., Grallert, H., Jaddoe, V. W. V., Lowe, W. L., Roumeliotaki, T., Hattersley, A. T., Lindi, V., Pahkala, K., Panoutsopoulou, K., Standl, M., Flexeder, C., Bouchard, L., Aagaard Nohr, E., Marina, L. S., Kogevinas, M., Niinikoski, H., Dedoussis, G., Heinrich, J., Reynolds, R. M., Lakka, T., Zeggini, E., Raitakari, O. T., Chatzi, L., Inskip, H. M., Bustamante, M., Hivert, M., Jarvelin, M., Sørensen, Thorkild I.A., Pennell, C., Felix, J. F., Jacobsson, B., Geller, F., Evans, D. M. & Lawlor, D. A., 2018, In: International journal of obesity (2005). 42, p. 775–784

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

    Stokholm, Jakob, Michaelsen, Kim F., Freathy, R. M. & EGG Consortium, E. C., 2019, In: Nature Genetics. 51, 5, p. 804-814

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Physiology insights

    Watanabe, R. M. & Hansen, Torben, 2016, The Genetics of Type 2 Diabetes and Related Traits: Biology, Physiology and Translation. Springer, p. 207-221 15 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review