Novo Nordisk Foundation Center for Basic Metabolic Research

  1. Published

    Epigenetic rewiring of skeletal muscle enhancers after exercise training supports a role in the whole-body function and human health

    Williams, K., Carrasquilla, Germán D., Ingerslev, L. R., Hochreuter, Mette Yde, Hansson, Svenja, Pillon, N. J., Donkin, I., Versteyhe, S., Zierath, Juleen R, Kilpeläinen, Tuomas O. & Barrès, Romain, 2021, In: Molecular Metabolism. 53, 13 p., 101290.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Genome-wide association study and functional characterization identifies candidate genes for insulin-stimulated glucose uptake

    Williamson, A., Norris, D. M., Yin, X., Broadaway, K. A., Moxley, A. H., Vadlamudi, S., Wilson, E. P., Jackson, A. U., Ahuja, V., Andersen, M. K., Arzumanyan, Z., Bonnycastle, L. L., Bornstein, S. R., Bretschneider, M. P., Buchanan, T. A., Chang, Y-C., Chuang, L-M., Chung, R-H., Clausen, T. D., Damm, P. & 31 others, Delgado, G. E., de Mello, V. D., Dupuis, J., Dwivedi, O. P., Erdos, M. R., Silva, L. F., Frayling, T. M., Gieger, C., Goodarzi, M. O., Guo, X., Gustafsson, S., Hakaste, L., Hammar, U., Hatem, G., Herrmann, S., Højlund, K., Horn, K., Jonsson, Anna Elisabet, Kovacs, P., Linneberg, Allan René, Mathiesen, Elisabeth, Friis, Carsten, Stinson, Sara, Suleman, Sufyan, Vistisen, D., Witte, D. R., Hansen, Torben, Lind, L., Schwarz, Peter, Grarup, Niels & Meta-Analysis of Glucose and Insulin-related Traits Consortium (MAGIC), M. O. G. A. I. T. C. (., 2023, In: Nature Genetics. 55, 6, p. 973-983 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Surgically Induced Interpregnancy Weight Loss and Prevalence of Overweight and Obesity in Offspring

    Willmer, M., Berglind, D., Sørensen, Thorkild I.A., Näslund, E., Tynelius, P. & Rasmussen, F., 2013, In: P L o S One. 8, 12, p. 1-7 7 p., e82247.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Gastric emptying, glucose responses, and insulin secretion after a liquid test meal: effects of exogenous glucagon-like peptide-1 (GLP-1)-(7-36) amide in type 2 (noninsulin-dependent) diabetic patients

    Willms, B., Werner, J., Holst, Jens Juul, Ørskov, Cathrine, Creutzfeldt, W. & Nauck, M. A., Jan 1996, In: Endocrinology. 81, 1, p. 327-32 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Genetic studies of abdominal MRI data identify genes regulating hepcidin as major determinants of liver iron concentration

    Wilman, H. R., Parisinos, C. A., Atabaki-Pasdar, N., Kelly, M., Thomas, E. L., Neubauer, S., Jennison, C., Ehrhardt, B., Baum, P., Schoelsch, C., Freijer, J., Grempler, R., Graefe-Mody, U., Hennige, A., Dings, C., Lehr, T., Scherer, N., Sihinecich, I., Pattou, F., Raverdi, V. & 31 others, Caiazzo, R., Torres, F., Verkindt, H., Mari, A., Tura, A., Giorgino, T., Bizzotto, Froguel, P., Brorsson, C., Brunak, Søren, De Masi, F., Pedersen, H., Banasik, Karina, Thomas, Cecilia Engel, Lundgaard, Agnete Troen, Nielsen, A., Mazzoni, G., Karaderi, Tugce, Rasmussen, Simon, Johansen, Joachim, Allesøe, R., Arumugam, Mani, Allin, K., Hansen, Torben, Hansen, T., Jonsson, Anna Elisabet, Pedersen, Oluf Borbye, Dutta, A., Vogt, J., drb459, drb459 & IMI-DIRECT consortium, I. C., 2019, In: Journal of Hepatology. 71, 3, p. 594-602 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. E-pub ahead of print

    Childhood adversity trajectories and weight status in young adult men: a register-based study including 359,783 Danish men

    Wimmelmann, Cathrine Lawaetz, Sejling, Christoffer, Clarke, Rebecca B, Elsenburg, Leonie K., Sørensen, Thorkild I.A. & Rod, Naja Hulvej, 2024, (E-pub ahead of print) In: International journal of obesity (2005).

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Why is it so difficult to measure glucagon-like peptide-1 in a mouse?

    Windeløv, Johanne Agerlin, Albrechtsen, Nicolai Jacob Wewer, Kuhre, Rune Ehrenreich, Jepsen, Sara Lind, Hornburg, D., Pedersen, Jens, Jensen, E. P., Galsgaard, Katrine Douglas, Winther-Sørensen, Marie, Ørgaard, A., Deacon, Carolyn F., Mann, Matthias, Kissow, Hannelouise, Hartmann, Bolette & Holst, Jens Juul, Oct 2017, In: Diabetologia. 60, 10, p. 2066-2075 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Use of anesthesia dramatically alters the oral glucose tolerance and insulin secretion in C57Bl/6 mice

    Windeløv, Johanne Agerlin, Pedersen, Jens & Holst, Jens Juul, Jun 2016, In: Physiological Reports. 4, 11, 6 p., e12824.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Quality control and conduct of genome-wide association meta-analyses

    Winkler, T. W., Day, F. R., Croteau-Chonka, D. C., Wood, A. R., Locke, A. E., Mägi, R., Ferreira, T., Fall, T., Graff, M., Justice, A. E., Luan, J., Gustafsson, S., Randall, J. C., Vedantam, S., Workalemahu, T., Kilpeläinen, T., Scherag, A., Esko, T., Kutalik, Z., Heid, I. M. & 2 others, Loos, Ruth & Genetic Investigation of Anthropometric Traits (GIANT) Consortium, G. I. O. A. T. (. C., May 2014, In: Nature Protocols (Online). 9, 5, p. 1192-1212 21 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

    Winkler, T. W., Justice, A. E., Graff, M., Barata, L., Feitosa, M. F., Chu, S., Czajkowski, J., Esko, T., Fall, T., Kilpeläinen, T. O., Lu, Y., Mägi, R., Mihailov, E., Pers, T. H., Rüeger, S., Teumer, A., Ehret, G. B., Ferreira, T., Heard-Costa, N. L., Karjalainen, J. & 31 others, Lagou, V., Mahajan, A., Neinast, M. D., Prokopenko, I., Simino, J., Teslovich, T. M., Jansen, R., Westra, H., White, C. C., Absher, D., Ahluwalia, Tarun Veer Singh, Ahmad, S., Albrecht, E., Alves, A. C., Bragg-Gresham, J. L., de Craen, A. J. M., Bis, J. C., Bonnefond, A., Boucher, G., Banasik, Karina, Grarup, Niels, Hansen, Torben, Jørgensen, T., Krarup, N. T., Linneberg, Allan René, Ribel-Madsen, R., Sparsø, T. H., Melbye, M., Pedersen, Oluf Borbye, Sørensen, Thorkild I.A. & CHARGE Consortium, C. C., 1 Oct 2015, In: P L o S Genetics. 11, 10, p. 1-42 42 p., e1005378.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Differential and shared genetic effects on kidney function between diabetic and non-diabetic individuals

    Winkler, T. W., Rasheed, H., Teumer, A., Gorski, M., Rowan, B. X., Stanzick, K. J., Thomas, L. F., Tin, A., Hoppmann, A., Chu, A. Y., Tayo, B., Thio, C. H. L., Cusi, D., Chai, J-F., Sieber, K. B., Horn, K., Li, M., Scholz, M., Cocca, M., Wuttke, M. & 31 others, van der Most, P. J., Yang, Q., Ghasemi, S., Nutile, T., Li, Y., Pontali, G., Günther, F., Dehghan, A., Correa, A., Parsa, A., Feresin, A., de Vries, A. P. J., Zonderman, A. B., Smith, A. V., Oldehinkel, A. J., De Grandi, A., Rosenkranz, A. R., Franke, A., Teren, A., Metspalu, A., Hicks, A. A., Morris, A. P., Tönjes, A., Morgan, A., Podgornaia, A. I., Christensen, K., Lind, L., Kovacs, P., Rossing, Peter, Loos, Ruth & LifeLines Cohort Study, L. C. S., 2022, In: Communications Biology . 5, p. 580 20 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Body mass index and risk of infections: a Mendelian randomization study of 101,447 individuals

    Winter-Jensen, M., Afzal, Shoaib, Jess, T., Nordestgaard, Børge & Allin, K. H., 2020, In: European Journal of Epidemiology. 35, 4, p. 347-354

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Protective succinate-SUCNR1 metabolic stress signaling gone bad

    Winther, Sally, Trauelsen, Mette & Schwartz, Thue W., 2021, In: Cell Metabolism. 33, 7, p. 1276-1278 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Restricting glycolysis impairs brown adipocyte glucose and oxygen consumption

    Winther, Sally, Isidor, Marie Sophie, Basse, A. L., Skjoldborg, N., Cheung, A., Quistorff, B. & Hansen, Jacob B., 2018, In: American Journal of Physiology: Endocrinology and Metabolism. 314, 3, p. E214-E223 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Utility of Plasma Concentration of Trimethylamine N-Oxide in Predicting Cardiovascular and Renal Complications in Individuals With Type 1 Diabetes

    Winther, S. A., Øllgaard, J. C., Tofte, N., Tarnow, L., Wang, Z., Ahluwalia, T. S., Jorsal, A., Theilade, S., Parving, H., Hansen, T. W., Hazen, S. L., Pedersen, Oluf Borbye & Rossing, Peter, 2019, In: Diabetes Care. 42, 8, p. 1512-1520

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Gut microbiota profile and selected plasma metabolites in type 1 diabetes without and with stratification by albuminuria

    Winther, S. A., Henriksen, P., Vogt, J. K., Hansen, T. H., Ahonen, L., Suvitaival, T., Zobel, E. H., Frimodt-Møller, M., Hansen, T. W., Hansen, Torben, Parving, H., Legido-Quigley, C., Rossing, Peter & Pedersen, Oluf Borbye, 2020, In: Diabetologia. 63, p. 2713-2724 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Plasma trimethylamine N-oxide and its metabolic precursors and risk of mortality, cardiovascular and renal disease in individuals with type 2-diabetes and albuminuria

    Winther, S. A., Øllgaard, J. C., Hansen, T. W., Von Scholten, B. J., Reinhard, H., Ahluwalia, Tarun Veer Singh, Wang, Z., Gæde, P., Parving, H. H., Hazen, S., Pedersen, Oluf Borbye & Rossing, Peter, 2021, In: PLoS ONE. 16, 3, 14 p., e0244402.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Trimethylamine-N-Oxide and Renal Complications, Cardiovascular Disease, and Mortality in Individuals with Type 2 Diabetes and Microalbuminuria

    Winther, S. A., Øllgaard, J. C., Hansen, T., von Scholten, B. J., Gaede, P., Parving, H., Pedersen, Oluf Borbye & Rossing, Peter, 2019, In: Journal of the American Society of Nephrology. 30, Kidney Week Edition, p. 904 1 p., SA-PO551.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  19. Published

    Hepatic steatosis and glucagon resistance develope in parallel resulting in hyperglucagonaemia and hyperaminoacidaemia

    Winther-Sørensen, Marie, Galsgaard, Katrine Douglas, Santos, A., Pedersen, J., Hassing, Anna Skab, Dall, M., Treebak, Jonas Thue, Kjeldsen, Sasha Alexandra Sampson, Knop, Filip Krag, Werge, M. P., Eriksen, P. L., Vilstrup, H., Gluud, Lise Lotte, Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2020, In: Diabetologia. 63, SUPPL 1, p. S71-S72 142.

    Research output: Contribution to journalConference abstract in journalResearch

  20. E-pub ahead of print
  21. Published

    Glucagon acutely regulates hepatic amino acid catabolism and the effect may be disturbed by steatosis

    Winther-Sørensen, M., Galsgaard, K. D., Santos, A., Trammell, S. A. J., Sulek, K., Kuhre, R. E., Pedersen, J., Andersen, D. B., Hassing, A. S., Dall, M., Treebak, J. T., Gillum, M. P., Torekov, S. S., Windeløv, J. A., Hunt, J. E., Kjeldsen, S. A. S., Jepsen, S. L., Vasilopoulou, C. G., Knop, F. K., Ørskov, C. & 7 others, Werge, M. P., Bisgaard, Hanne Cathrine, Eriksen, P. L., Vilstrup, H., Gluud, Lise Lotte, Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2020, In: Molecular Metabolism. 42, 18 p., 101080.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Hepatic Glucose Production, Ureagenesis, and Lipolysis Quantified using the Perfused Mouse Liver Model

    Winther-Sørensen, Marie, Kemp, I. M., Bisgaard, Hanne Cathrine, Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2023, In: Journal of Visualized Experiments. 2023, 200, e65596.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Meta-analysis of fecal metagenomes reveals global microbial signatures that are specific for colorectal cancer

    Wirbel, J., Pyl, P. T., Kartal, E., Zych, K., Kashani, A., Milanese, A., Fleck, J. S., Voigt, A. Y., Palleja, A., Ponnudurai, R., Sunagawa, S., Coelho, L. P., Schrotz-King, P., Vogtmann, E., Habermann, N., Niméus, E., Thomas, A. M., Manghi, P., Gandini, S., Serrano, D. & 15 others, Mizutani, S., Shiroma, H., Shiba, S., Shibata, T., Yachida, S., Yamada, T., Waldron, L., Naccarati, A., Segata, N., Sinha, R., Ulrich, C. M., Brenner, H., Arumugam, Mani, Bork, P. & Zeller, G., 2019, In: Nature Medicine. 25, 4, p. 679-689 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Peptide YY3-36 and glucagon-like peptide-1 in functional dyspepsia. Secretion and role in symptom generation

    Witte, A., Hilsted, Linda, Holst, Jens Juul & Schmidt, P. T., Apr 2016, In: Scandinavian Journal of Gastroenterology. 51, 4, p. 400-409 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Involvement of endogenous glucagon-like peptide-1 in regulation of gastric motility and pancreatic endocrine secretion

    Witte, A., Grybäck, P., Jacobsson, H., Näslund, E., Hellström, P. M., Holst, Jens Juul, Hilsted, Linda & Schmidt, P. T., 2011, In: Scandinavian Journal of Gastroenterology. Supplement. 46, 4, p. 428-35 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    The exercise-induced long noncoding RNA CYTOR promotes fast-twitch myogenesis in aging

    Wohlwend, M., Laurila, P., William, K., Romani, M., Lima, T., Pattawaran, P., Benegiamo, G., Salonen, M., Schneider, B. L., Lahti, J., Eriksson, J. G., Barrès, Romain, Wisloff, U., Moreira, José & Auwerx, J., 2021, In: Science Translational Medicine. 13, 623, 14 p., eabc7367.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Fueling the fire of adipose thermogenesis

    Wolfrum, C. & Gerhart-Hines, Zach, 2022, In: Science. 375, 6586, p. 1229-1231 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Gastric emptying of solutions containing the natural sweetener erythritol and effects on gut hormone secretion in humans: A pilot dose-ranging study

    Wolnerhanssen, B. K., Drewe, J., Verbeure, W., le Roux, C. W., Dellatorre-Teixeira, L., Rehfeld, Jens Frederik, Holst, Jens Juul, Hartmann, Bolette, Tack, J., Peterli, R., Beglinger, C. & Meyer-Gerspach, A. C., 2021, In: Diabetes, Obesity and Metabolism. 23, 6, p. 1311-1321

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    A Genome-Wide Association Study of IVGTT-Based Measures of First Phase Insulin Secretion Refines the Underlying Physiology of Type 2 Diabetes Variants

    Wood, A. R., Jonsson, A., Jackson, A. U., Wang, T-N., van Leewen, N., Palmer, N. D., Kobes, S., Deelen, J., Boquete-Vilarino, L., Paananen, J., Stančáková, A., Boomsma, D. I., de Geus, E. J., Eekhoff, E. M., Fritsche, A., Kramer, M., Nijpels, G., Simonis-Bik, A. M. C., van Haeften, T. W., Mahajan, A. & 31 others, Boehnke, M., Bergman, R. N., Tuomilehto, J., Collins, F. S., Mohlke, K. L., Banasik, Karina, Groves, C. J., McCarthy, M. I., Pearson, E. R., Natali, A., Mari, A., Buchanan, T. A., Taylor, K. D., Xiang, A. H., Gjesing, A. P., Grarup, Niels, Eiberg, Hans Rudolf Lytchoff, Pedersen, Oluf Borbye, Chen, Y., Laakso, M., Norris, J. M., Smith, U., Wagenknecht, L. E., Baier, L., Bowden, D. W., Hansen, Torben, Walker, M., Watanabe, R. M., 't Hart, L. M., Hanson, R. L. & Frayling, T. M., 2017, In: Diabetes. 66, 8, p. 2296-2309

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Synaptotagmin-7 phosphorylation mediates GLP-1-dependent potentiation of insulin secretion from β-cells

    Wu, B., Wei, S., Petersen, N., Ali, Y., Wang, X., Bacaj, T., Rorsman, P., Hong, W., Südhof, T. C. & Han, W., 11 Aug 2015, In: National Academy of Sciences. Proceedings. 112, 32, p. 9996-10001 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Linking Microbiota to Human Diseases: A Systems Biology Perspective

    Wu, H., Tremaroli, V. & Bäckhed, F., 6 Nov 2015, In: Trends in Endocrinology and Metabolism. 26, 12, p. 758-70 13 p.

    Research output: Contribution to journalReviewResearchpeer-review

  32. Published

    The Gut Microbiota in Prediabetes and Diabetes: A Population-Based Cross-Sectional Study

    Wu, H., Tremaroli, V., Schmidt, C., Lundqvist, A., Olsson, L. M., Kramer, M., Gummesson, A., Perkins, R., Bergstrom, G. & Backhed, F., 2020, In: Cell Metabolism. 32, 3, p. 379-390.e3 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Metformin alters the gut microbiome of individuals with treatment-naive type 2 diabetes, contributing to the therapeutic effects of the drug

    Wu, H., Esteve, E., Tremaroli, V., Khan, M. T., Caesar, R., Mannerås-Holm, L., Ståhlman, M., Olsson, L. M., Serino, M., Planas-Fèlix, M., Xifra, G., Mercader, J. M., Torrents, D., Burcelin, R., Ricart, W., Perkins, R., Fernàndez-Real, J. M. & Bäckhed, F., Jul 2017, In: Nature Medicine. 23, 7, p. 850-858 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Identification of rat genes by TWINSCAN gene prediction, RT-PCR, and direct sequencing

    Wu, J. Q., Shteynberg, D., Arumugam, Mani, Gibbs, R. A. & Brent, M. R., 2004, In: Genome Research. 14, 4, p. 665-71 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    SOAPfusion: a robust and effective computational fusion discovery tool for RNA-seq reads

    Wu, J., Zhang, W., Huang, S., He, Z., Cheng, Y., Wang, J., Lam, T., Peng, Z. & Yiu, S., 2013, In: Bioinformatics. 29, 23, p. 2971-2978 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Tumor suppressor ASXL1 is essential for the activation of INK4B expression in response to oncogene activity and anti-proliferative signals

    Wu, X., Bekker-Jensen, I. H., Christensen, J., Rasmussen, K. D., Sidoli, S., Qi, Y., Kong, Y., Wang, X., Cui, Y., Xiao, Z., Xu, G., Williams, K., Rappsilber, J., Sønderby, C. K., Winther, Ole, Jensen, O. N. & Helin, K., 2015, In: Cell Research. 25, p. 1205-1218 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Universal infant health interventions and young adult outcomes

    Wüst, Miriam, Mortensen, Erik Lykke, Osler, Merete & Sørensen, Thorkild I.A., 2018, In: Health Economics. 27, 8, p. 1319-1324 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function

    Wyss, A. B., Sofer, T., Lee, M. K., Terzikhan, N., Nguyen, J. N., Lahousse, L., Latourelle, J. C., Smith, A. V., Bartz, T. M., Feitosa, M. F., Gao, W., Ahluwalia, T. S., Tang, W., Oldmeadow, C., Duan, Q., de Jong, K., Wojczynski, M. K., Wang, X-Q., Noordam, R., Hartwig, F. P. & 82 others, Jackson, V. E., Wang, T., Obeidat, M., Hobbs, B. D., Huan, T., Gui, H., Parker, M. M., Hu, D., Mogil, L. S., Kichaev, G., Jin, J., Graff, M., Harris, T. B., Kalhan, R., Heckbert, S. R., Paternoster, L., Burkart, K. M., Liu, Y., Holliday, E. G., Wilson, J. G., Vonk, J. M., Sanders, J. L., Barr, R. G., de Mutsert, R., Baptista Menezes, A. M., Adams, H. H. H., van den Berge, M., Joehanes, R., Levin, A. M., Liberto, J., Launer, L. J., Morrison, A. C., Sitlani, C. M., Celedon, J. C., Kritchevsky, S. B., Scott, R. J., Christensen, K., Rotter, J. I., Bonten, T. N., Wehrmeister, F. C., Bosse, Y., Xiao, S., Oh, S., Franceschini, N., Brody, J. A., Kaplan, R. C., Lohman, K., McEvoy, M., Province, M. A., Rosendaal, F. R., Taylor, K. D., Nickle, D. C., Williams, L. K., Burchard, E. G., Wheeler, H. E., Sin, D. D., Gudnason, V., North, K. E., Fornage, M., Psaty, B. M., Myers, R. H., O'Connor, G., Hansen, Torben, Laurie, C. C., Cassano, P. A., Sung, J., Kim, W. J., Attia, J. R., Lange, L., Boezen, H. M., Thyagarajan, B., Rich, S. S., Mook-Kanamori, D. O., Horta, B. L., Uitterlinden, A. G., Im, H. K., Cho, M. H., Brusselle, G. G., Gharib, S. A., Dupuis, J., Manichaikul, A. & London, S. J., 2018, In: Nature Communications. 9, 15 p., 2976.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    High-fat feeding rather than obesity drives taxonomical and functional changes in the gut microbiota in mice

    Xiao, L., Sonne, S. B., Feng, Q., Chen, N., Xia, Z., Li, X., Fang, Z., Zhang, D., Fjære, E., Midtbø, L. K., Derrien, M., Hugenholtz, F., Tang, L., Li, J., Zhang, J., Liu, C., Hao, Q., Vogel, U. B., Mortensen, A., Kleerebezem, M. & 8 others, Licht, T. R., Yang, H., Wang, J., Li, Y., Arumugam, Mani, Wang, J., Madsen, L. & Kristiansen, Karsten, 8 Apr 2017, In: Microbiome. 5, 12 p., 43.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    A catalog of the mouse gut metagenome: [incl. Author Correction]

    Xiao, L., Feng, Q., Liang, S., Sonne, S. B., Xia, Z., Qiu, X., Li, X., Long, H., Zhang, J., Zhang, D., Liu, C., Fang, Z., Chou, J., Glanville, J., Hao, Q., Kotowska, D. E., Colding, C. S., Licht, T. R., Wu, D., Yu, J. & 17 others, Sung, J. J. Y., Liang, Q., Li, J., Jia, H., Lan, Z., Tremaroli, V., Dworzynski, P., Nielsen, H. B., Bäckhed, G. F., Dore, J., Le Chatelier, E., Ehrlich, S. D., Lin, J. C., Arumugam, Mani, Wang, J., Madsen, L. & Kristiansen, Karsten, 2015, In: Nature Biotechnology. 33, 10, p. 1103-1108 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Glutamate prevents intestinal atrophy via luminal nutrient sensing in a mouse model of total parenteral nutrition

    Xiao, W., Feng, Y., Holst, Jens Juul, Hartmann, Bolette, Yang, H. & Teitelbaum, D. H., May 2014, In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 28, 5, p. 2073-87 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Genetic variants associated with glycine metabolism and their role in insulin sensitivity and type 2 diabetes

    Xie, W., Wood, A. R., Lyssenko, V., Weedon, M. N., Knowles, J. W., Alkayyali, S., Assimes, T. L., Quertermous, T., Abbasi, F., Paananen, J., Häring, H., Hansen, T., Pedersen, O., Smith, U., Laakso, M., Dekker, J. M., Nolan, J. J., Groop, L., Ferrannini, E., Adam, K-P. & 4 others, Gall, W. E., Frayling, T. M., Walker, M. & MAGIC Investigators, M. I., Jun 2013, In: Diabetes. 62, 6, p. 2141-50 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    SOAPdenovo-Trans: de novo transcriptome assembly with short RNA-Seq reads

    Xie, Y., Wu, G., Tang, J., Luo, R., Patterson, J., Liu, S., Huang, W., He, G., Gu, S., Li, S., Zhou, X., Lam, T., Li, Y., Xu, X., Wong, G. K. & Wang, J., 2014, In: Bioinformatics. 30, 12, p. 1660-1666 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Inherited coding variants at the CDKN2A locus influence susceptibility to acute lymphoblastic leukaemia in children

    Xu, H., Zhang, H., Yang, W., Yadav, R., Morrison, A. C., Qian, M., Devidas, M., Liu, Y., Perez-Andreu, V., Zhao, X., Gastier-Foster, J. M., Lupo, P. J., Neale, G., Raetz, E., Larsen, E., Bowman, W. P., Carroll, W. L., Winick, N., Williams, R., Hansen, T. & 13 others, Holm, Jens-Christian, Mardis, E., Fulton, R., Pui, C., Zhang, J., Mullighan, C. G., Evans, W. E., Hunger, S. P., Gupta, R., Schmiegelow, Kjeld, Loh, M. L., Relling, M. V. & Yang, J. J., 2015, In: Nature Communications. 6, p. 1-7 7 p., 7553.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    A semaphorin-plexin-Rasal1 signaling pathway inhibits gastrin expression and protects against peptic ulcers

    Xu, R., Höß, C., Swiercz, J. M., Brandt, D. T., Lutz, V., Petersen, N., Li, R., Zhao, D., Oleksy, A., Creigh-Pulatmen, T., Trokter, M., Fedorova, M., Atzberger, A., Strandby, R. B., Olsen, A. A., Achiam, M. P., Matthews, D., Huber, M., Gröne, H-J., Offermanns, S. & 1 others, Worzfeld, T., 2022, In: Science Translational Medicine. 14, 654, eabf1922.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Application of tandem biotransformation for biosynthesis of new pentacyclic triterpenoid derivatives with neuroprotective effect

    Xu, S., Chen, H., Fan, Yong, Xu, W. & Zhang, J., 2020, In: Bioorganic & Medicinal Chemistry Letters. 30, 4, 5 p., 126947.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    New 30-norlupane derivatives through chemical-microbial semi-synthesis of betulinic acid and their neuroprotective effect

    Xu, S., Chen, H., Yang, Z., Lyu, Liwei, Fan, Yong, Sha, M., Zhang, J., Xu, W. & Lin, Y., 2020, In: Bioorganic & Medicinal Chemistry Letters. 30, 17, 127407.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    In the rat pancreas, somatostatin tonically inhibits glucagon secretion and is required for glucose-induced inhibition of glucagon secretion

    Xu, S. F. S., Andersen, Daniel Bjørklund, Izarzugaza, J. M. G., Kuhre, Rune Ehrenreich & Holst, Jens Juul, 2020, In: Acta Physiologica. 229, 3, 15 p., e13464.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Resequencing 50 accessions of cultivated and wild rice yields markers for identifying agronomically important genes

    Xu, X., Liu, X., Ge, S., Jensen, J. D., Hu, F., Li, X., Dong, Y., Gutenkunst, R. N., Fang, L., Huang, L., Li, J., He, W., Zhang, G., Zheng, X., Zhang, F., Li, Y., Yu, C., Kristiansen, K., Zhang, X., Wang, J. & 5 others, Wright, M., McCouch, S., Nielsen, Rasmus, Wang, J. & Wang, W., 2012, In: Nature Biotechnology. 30, 1, p. 105-111 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Single-cell exome sequencing reveals single-nucleotide mutation characteristics of a kidney tumor: Cell

    Xu, X., Hou, Y., Yin, X., Bao, L., Tang, A., Song, L., Li, F., Tsang, S., Wu, K., Wu, H., He, W., Zeng, L., Xing, M., Wu, R., Jiang, H., Liu, X., Cao, D., Guo, G., Hu, X., Gui, Y. & 19 others, Li, Z., Xie, W., Sun, X., Shi, M., Cai, Z., Wang, B., Zhong, M., Li, J., Lu, Z., Gu, N., Zhang, X., Goodman, L., Bolund, L., Wang, J., Yang, H., Kristiansen, Karsten, Dean, M., Li, Y. & Wang, J., 2012, In: Cell. 148, 5, p. 886-895 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review