Novo Nordisk Foundation Center for Basic Metabolic Research

  1. Published

    PPARG Pro12Ala Ala carriers exhibit greater improvements in peripheral insulin sensitivity in response to 12 weeks of aerobic exercise training

    Blond, Martin Bæk, Schnurr, T. M., Rasenkilde, M., Quist, Jonas Salling, Gram, A. S., Reichkendler, M. H., Auerbach, P. L., Nordby, P., Skovgaard, Lene Theil, Ribel-Madsen, R., Justesen, Johanne Marie, Kilpeläinen, Tuomas O., Ploug, Thorkil, Stallknecht, Bente Merete & Hansen, Torben, 2019, In: Physiological Genomics. 51, 6, p. 254-260

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Human Brown Adipocyte Thermogenesis Is Driven by beta 2-AR Stimulation

    Blondin, D. P., Nielsen, S., Kuipers, E. N., Severinsen, M. C., Jensen, V. H., Miard, S., Jespersen, N. Z., Kooijman, S., Boon, M. R., Fortin, M., Phoenix, S., Frisch, F., Guerin, B., Turcotte, E. E., Haman, F., Richard, D., Picard, F., Rensen, P. C. N., Schéele, Camilla Charlotte Nielsen & Carpentier, A. C., 2020, In: Cell Metabolism. 32, 2, p. 287-300.e7 21 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Potent inhibitory effects of transplantable rat glucagonomas and insulinomas on the respective endogenous islet cells are associated with pancreatic apoptosis.

    Blume, N., Skouv, J., Larsson, L., Holst, Jens Juul & Madsen, O. D., 1995, In: J. Clin. Invest.. 96, p. 2227-2235

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Variations in the prevalence of obesity among european countries, and a consideration of possible causes

    Blundell, J. E., Baker, J. L., Boyland, E., Blaak, E., Charzewska, J., De Henauw, S., Frühbeck, G., Gonzalez-Gross, M., Hebebrand, J., Holm, Lotte, Kriaucioniene, V., Lissner, L., Oppert, J. M., Schindler, K., Silva, A. M. & Woodward, E., 2017, In: Obesity Facts. 10, p. 25-37 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Impact of individual and environmental factors on dietary or lifestyle interventions to prevent type 2 diabetes development: a systematic review

    Bodhini, D., Morton, R. W., Santhakumar, V., Nakabuye, Mariam, Pomares-Millan, H., Clemmensen, Christoffer, Fitzpatrick, S. L., Guasch Ferre, Marta, Pankow, J. S., Ried-Larsen, M., Franks, P. W., Tobias, D. K., Merino, Jordi, Mohan, V., Loos, Ruth & ADA/EASD PMDI, A. P., 2023, In: Communications Medicine. 3, 17 p., 133.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Role of sociodemographic, clinical, behavioral, and molecular factors in precision prevention of type 2 diabetes: a systematic review

    Bodhini, D., Morton, R. W., Santhakumar, V., Nakabuye, Mariam, Pomares-Millan, H., Clemmensen, Christoffer, Fitzpatrick, S. L., Guasch Ferre, Marta, Pankow, J. S., Ried-Larsen, M., Franks, P. W., Tobias, D. K., Merino, Jordi, Mohan, V., Loos, Ruth & ADA/EASD Precision Medicine in Diabetes Initiative, A. P. M. I. D. I., 2023, medRxiv.

    Research output: Working paperPreprintResearch

  7. Published

    Glucagon-like peptide-2 in umbilical cord blood from mature infants

    Bodé, S., Hartmann, Bolette, Holst, Jens Juul & Greisen, Gorm, 2007, In: Neonatology. 91, 1, p. 49-53 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Stool energy density is positively correlated to intestinal transit time and related to microbial enterotypes

    Boekhorst, J., Venlet, N., Procházková, Nicola, Hansen, M. L., Lieberoth, C. B., Bahl, M. I., Lauritzen, Lotte, Pedersen, Oluf Borbye, Licht, T. R., Kleerebezem, M. & Roager, Henrik Munch, 2022, In: Microbiome. 10, 10 p., 223.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Incretin Hormones and Type 2 Diabetes-Mechanistic Insights and Therapeutic Approaches

    Boer, G. A. & Holst, Jens Juul, 2020, In: Biology. 9, 12, 20 p., 473.

    Research output: Contribution to journalReviewResearchpeer-review

  10. Published

    GIP receptor deletion in mice confers resistance to HFD-induced obesity via alterations in energy expenditure and adipose tissue lipid metabolism

    Boer, G. A., Keenan, S. N., Miotto, P. M., Holst, Jens Juul & Watt, M. J., 2021, In: American Journal of Physiology: Endocrinology and Metabolism. 320, 4, p. E835-E845 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Glucose-dependent insulinotropic polypeptide receptor antagonist treatment causes a reduction in weight gain in ovariectomised high fat diet-fed mice

    Boer, G. A., Dal, Jenna Elizabeth Hunt, Gabe, M. B. N., Windeløv, Johanne Agerlin, Sparre-Ulrich, A. H., Hartmann, Bolette, Holst, Jens Juul & Rosenkilde, Mette, 2022, In: British Journal of Pharmacology. 179, 18, p. 4486-4499

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Pharmacokinetics of exogenous GIP(1-42) in C57Bl/6 mice; Extremely rapid degradation but marked variation between available assays

    Boer, G. A., Hartmann, Bolette & Holst, Jens Juul, 2021, In: Peptides. 136, 7 p., 170457.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Variants at DGKB/TMEM195, ADRA2A, GLIS3 and C2CD4B loci are associated with reduced glucose-stimulated beta cell function in middle-aged Danish people

    Boesgaard, T. W., Grarup, Niels, Jørgensen, T., Borch-Johnsen, K., Hansen, Torben, Pedersen, Oluf Borbye & Meta-Analysis of Glucose and Insulin-Related Trait Consortium (MAGIC), M. O. G. A. I. T. C. (., 1 Aug 2010, In: Diabetologia. 53, 8, p. 1647-55 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    The common SLC30A8 Arg325Trp variant is associated with reduced first-phase insulin release in 846 non-diabetic offspring of type 2 diabetes patients--the EUGENE2 study

    Boesgaard, T. W., Zilinskaite, J., Vänttinen, M., Laakso, M., Jansson, P., Hammarstedt, A., Smith, U., Stefan, N., Fritsche, A., Häring, H., Hribal, M., Sesti, G., Zobel, D. P., Pedersen, Oluf Borbye, Hansen, Torben & EUGENE 2 Consortium, E. 2. C., 2008, In: Diabetologia. 51, 5, p. 816-20 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Further evidence that mutations in INS can be a rare cause of Maturity-Onset Diabetes of the Young (MODY)

    Boesgaard, T. W., Pruhova, S., Andersson, E. A., Cinek, O., Obermannova, B., Lauenborg, J., Damm, Peter, Bergholdt, R., Pociot, Flemming, Pisinger, C., Barbetti, F., Lebl, J., Pedersen, Oluf Borbye & Hansen, Torben, 1 Jan 2010, In: B M C Medical Genetics. 11, p. 42

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Variant near ADAMTS9 known to associate with type 2 diabetes is related to insulin resistance in offspring of type 2 diabetes patients--EUGENE2 study

    Boesgaard, T. W., Gjesing, A. P., Grarup, N., Rutanen, J., Jansson, P., Hribal, M. L., Sesti, G., Fritsche, A., Stefan, N., Staiger, H., Häring, H., Smith, U., Laakso, M., Pedersen, Oluf Borbye, Hansen, T. & EUGENE2 Consortium, E. C., 2009, In: PLoS ONE. 4, 9, p. e7236

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Insufficient sleep predicts poor weight loss maintenance after one year

    Bogh, A. F., Jensen, Simon Birk Kjær, Juhl, C. R., Janus, C., Sandsdal, Rasmus Michael, Lundgren, J. R., Noer, M. H., Vu, N. Q., Fiorenza, Matteo, Stallknecht, Bente Merete, Holst, Jens Juul, Madsbad, Sten & Torekov, Signe Sørensen, 2023, In: Sleep. 46, 5, 12 p., zsac295.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Does the sex of one's co-twin affect height and BMI in adulthood? A study of dizygotic adult twins from 31 cohorts

    Bogl, L. H., Jelenkovic, A., Vuoksimaa, E., Ahrenfeldt, L., Pietiläinen, K. H., Stazi, M. A., Fagnani, C., D'Ippolito, C., Hur, Y-M., Jeong, H-U., Silberg, J. L., Eaves, L. J., Maes, H. H., Bayasgalan, G., Narandalai, D., Cutler, T. L., Kandler, C., Jang, K. L., Christensen, K., Skytthe, A. & 56 others, Kyvik, K. O., Cozen, W., Hwang, A. E., Mack, T. M., Derom, C. A., Vlietinck, R. F., Nelson, T. L., Whitfield, K. E., Corley, R. P., Huibregtse, B. M., McAdams, T. A., Eley, T. C., Gregory, A. M., Krueger, R. F., McGue, M., Pahlen, S., Willemsen, G., Bartels, M., van Beijsterveldt, T. C. E. M., Pang, Z., Tan, Q., Zhang, D., Martin, N. G., Medland, S. E., Montgomery, G. W., Hjelmborg, J. V. B., Rebato, E., Swan, G. E., Krasnow, R., Busjahn, A., Lichtenstein, P., Öncel, S. Y., Aliev, F., Baker, L. A., Tuvblad, C., Siribaddana, S. H., Hotopf, M., Sumathipala, A., Rijsdijk, F., Magnusson, P. K. E., Pedersen, N. L., Aslan, A. K. D., Ordoñana, J. R., Sánchez-Romera, J. F., Colodro-Conde, L., Duncan, G. E., Buchwald, D., Tarnoki, A. D., Tarnoki, D. L., Yokoyama, Y., Hopper, J. L., Loos, R. J. F., Boomsma, D. I., Sørensen, Thorkild I.A., Silventoinen, K. & Kaprio, J., 2017, In: Biology of Sex Differences. 8, 12 p., 14.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Dairy proteins, dairy lipids, and postprandial lipemia in persons with abdominal obesity (DairyHealth): a 12-wk, randomized, parallel-controlled, double-blinded, diet intervention study

    Bohl, M., Bjørnshave, A., Rasmussen, K. V., Schioldan, A. G., Amer, B., Larsen, M. K., Dalsgaard, T. K., Holst, Jens Juul, Herrmann, A., O'Neill, S., O'Driscoll, L., Afman, L., Jensen, E., Christensen, M. M., Gregersen, S. & Hermansen, K., Apr 2015, In: The American Journal of Clinical Nutrition. 101, 4, p. 870-8 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Accelerated protein digestion and amino acid absorption after Roux-en-Y gastric bypass

    Bojsen-Møller, A. K., Jacobsen, S. H., Dirksen, C., Jørgensen, N. B., Reitelseder, S., Jensen, J. B., Kristiansen, V. B., Holst, Jens Juul, van Hall, Gerrit & Madsbad, Sten, Sep 2015, In: The American Journal of Clinical Nutrition. 102, 3, p. 600-7 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Increased Hepatic Insulin Clearance After Roux-en-Y Gastric Bypass

    Bojsen-Møller, K. N., Dirksen, C., Jørgensen, N. B., Jacobsen, S. H., Hansen, D. L., Worm, Dorte, Naver, L., Kristiansen, V. B., Holst, Jens Juul & Madsbad, Sten, 22 Apr 2013, In: Journal of Clinical Endocrinology and Metabolism. 98, 6, p. E1066-E1071 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Hepatic Insulin Clearance in Regulation of Systemic Insulin Concentrations—Role of Carbohydrate and Energy Availability

    Bojsen-Møller, K. N., Lundsgaard, Anne-Marie, Madsbad, Sten, Kiens, Bente & Holst, Jens Juul, Nov 2018, In: Diabetes. 67, 11, p. 2129-2136 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Variable reliability of surrogate measures of insulin sensitivity after Roux-en-Y gastric bypass

    Bojsen-Møller, K. N., Dirksen, C., Svane, M. S., Jørgensen, N. B., Holst, Jens Juul, Richter, Erik A. & Madsbad, Sten, 2017, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 312, 5, p. R797-R805 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Early enhancements of hepatic and later of peripheral insulin sensitivity combined with increased postprandial insulin secretion contribute to improved glycemic control after Roux-en-Y gastric bypass

    Bojsen-Møller, K. N., Dirksen, C., Jørgensen, N. B., Jacobsen, S. H., Serup, A. K. L., Albers, P. H., Hansen, D. L., Worm, D., Naver, L., Kristiansen, V. B., Wojtaszewski, Jørgen F P, Kiens, Bente, Holst, Jens Juul, Richter, Erik A. & Madsbad, Sten, 2014, In: Diabetes. 63, 5, p. 1725-1737 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Follistatin secretion is enhanced by protein, but not glucose or fat ingestion in obese persons independently of previous gastric bypass surgery

    Bojsen-Møller, K. N., Svane, M. S., Jensen, Christian Zinck, Kjeldsen, Sasha Alexandra Sampson, Holst, Jens Juul, Albrechtsen, Nicolai Jacob Wewer & Madsbad, Sten, 2021, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 320, 5, p. G753-G758

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Primary weight loss failure after Roux-en-Y gastric bypass is characterized by impaired gut-hormone mediated regulation of food intake

    Bojsen-Møller, Kirstine Nyvold, Svane, M. S., Martinussen, C., Dirksen, Carsten Moro, Jørgensen, Nils Bruun, Jensen, Jens-Erik Beck, Jensen, Christian Zinck, Torekov, Signe Sørensen, Kristiansen, V. B., Rehfeld, Jens Frederik, Bork-Jensen, J., Grarup, Niels, Hansen, Torben, Hartmann, Bolette, Holst, Jens Juul & Madsbad, Sten, 2023, In: International Journal of Obesity. 47, 11, p. 1143-1151 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Primaer hyperparatyroidisme--forekomst, symptomer, komplikationer og behandling

    Bollerslev, J., Ogard, C. G., Schwarz, Peter, drb459, drb459, Vestergaard, P. & drb459, drb459, 21 Feb 2005, In: Ugeskrift for Laeger. 167, 8, p. 910-4 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Molecular characterization of a 40-kDa outer membrane protein, FomA, of Fusobacterium periodonticum and comparison with Fusobacterium nucleatum

    Bolstad, A. I., Høgh, Birthe & Jensen, H. B., Oct 1995, In: Oral Microbiology and Immunology. 10, 5, p. 257-64 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Reproducible, interactive, scalable and extensible microbiome data science using QIIME 2

    Bolyen, E., Rideout, J. R., Dillon, M. R., Bokulich, N., Abnet, C. C., Al-Ghalith, G. A., Alexander, H., Alm, E. J., Arumugam, M., Asnicar, F., Bai, Y., Bisanz, J. E., Bittinger, K., Brejnrod, A., Brislawn, C. J., Brown, C. T., Callahan, B. J., Caraballo-Rodriguez, A. M., Chase, J., Cope, E. K. & 92 others, Da Silva, R., Diener, C., Dorrestein, P. C., Douglas, G. M., Durall, D. M., Duvallet, C., Edwardson, C. F., Ernst, M., Estaki, M., Fouquier, J., Gauglitz, J. M., Gibbons, S. M., Gibson, D. L., Gonzalez, A., Gorlick, K., Guo, J., Hillmann, B., Holmes, S., Holste, H., Huttenhower, C., Huttley, G. A., Janssen, S., Jarmusch, A. K., Jiang, L., Kaehler, B. D., Bin Kang, K., Keefe, C. R., Keim, P., Kelley, S. T., Knights, D., Koester, I., Kosciolek, T., Kreps, J., Langille, M. G. I., Lee, J., Ley, R., Liu, Y., Loftfield, E., Lozupone, C., Maher, M., Marotz, C., Martin, B. D., McDonald, D., McIver, L. J., Melnik, A. V., Metcalf, J. L., Morgan, S. C., Morton, J. T., Naimey, A. T., Navas-Molina, J. A., Nothias, L. F., Orchanian, S. B., Pearson, T., Peoples, S. L., Petras, D., Preuss, M. L., Pruesse, E., Rasmussen, L. B., Rivers, A., Robeson, M. S. ,. I., Rosenthal, P., Segata, N., Shaffer, M., Shiffer, A., Sinha, R., Song, S. J., Spear, J. R., Swafford, A. D., Thompson, L. R., Torres, P. J., Trinh, P., Tripathi, A., Turnbaugh, P. J., Ul-Hasan, S., vander Hooft, J. J. J., Vargas, F., Vazquez-Baeza, Y., Vogtmann, E., von Hippel, M., Walters, W., Wan, Y., Wang, M., Warren, J., Weber, K. C., Williamson, C. H. D., Willis, A. D., Xu, Z. Z., Zaneveld, J. R., Zhang, Y., Zhu, Q., Knight, R. & Caporaso, J. G., 2019, In: Nature Biotechnology. 37, 8, p. 852-857

    Research output: Contribution to journalLetterResearchpeer-review

  30. Published

    Author Correction: Reproducible, interactive, scalable and extensible microbiome data science using QIIME 2 (Nature Biotechnology, (2019), 37, 8, (852-857), 10.1038/s41587-019-0209-9)

    Bolyen, E., Rideout, J. R., Dillon, M. R., Bokulich, N. A., Abnet, C. C., Al-Ghalith, G. A., Alexander, H., Alm, E. J., Arumugam, M., Asnicar, F., Bai, Y., Bisanz, J. E., Bittinger, K., Brejnrod, A., Brislawn, C. J., Brown, C. T., Callahan, B. J., Caraballo-Rodríguez, A. M., Chase, J., Cope, E. K. & 92 others, Da Silva, R., Diener, C., Dorrestein, P. C., Douglas, G. M., Durall, D. M., Duvallet, C., Edwardson, C. F., Ernst, M., Estaki, M., Fouquier, J., Gauglitz, J. M., Gibbons, S. M., Gibson, D. L., Gonzalez, A., Gorlick, K., Guo, J., Hillmann, B., Holmes, S., Holste, H., Huttenhower, C., Huttley, G. A., Janssen, S., Jarmusch, A. K., Jiang, L., Kaehler, B. D., Kang, K. B., Keefe, C. R., Keim, P., Kelley, S. T., Knights, D., Koester, I., Kosciolek, T., Kreps, J., Langille, M. G. I., Lee, J., Ley, R., Liu, Y. X., Loftfield, E., Lozupone, C., Maher, M., Marotz, C., Martin, B. D., McDonald, D., McIver, L. J., Melnik, A. V., Metcalf, J. L., Morgan, S. C., Morton, J. T., Naimey, A. T., Navas-Molina, J. A., Nothias, L. F., Orchanian, S. B., Pearson, T., Peoples, S. L., Petras, D., Preuss, M. L., Pruesse, E., Rasmussen, L. B., Rivers, A., Robeson, M. S., Rosenthal, P., Segata, N., Shaffer, M., Shiffer, A., Sinha, R., Song, S. J., Spear, J. R., Swafford, A. D., Thompson, L. R., Torres, P. J., Trinh, P., Tripathi, A., Turnbaugh, P. J., Ul-Hasan, S., van der Hooft, J. J. J., Vargas, F., Vázquez-Baeza, Y., Vogtmann, E., von Hippel, M., Walters, W., Wan, Y., Wang, M., Warren, J., Weber, K. C., Williamson, C. H. D., Willis, A. D., Xu, Z. Z., Zaneveld, J. R., Zhang, Y., Zhu, Q., Knight, R. & Caporaso, J. G., 1 Sep 2019, In: Nature Biotechnology. 37, 9, p. 1091 1 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  31. Published
  32. Published

    The Accuracy of Hemoglobin A1c and Fructosamine Evaluated by Long-Term Continuous Glucose Monitoring in Patients with Type 2 Diabetes Undergoing Hemodialysis

    Bomholt, T., Rix, M., Almdal, Thomas Peter, Knop, Filip Krag, Rosthøj, Susanne, Heinrich, N. S., Jørgensen, M. B., Larsson, A., Hilsted, Linda, Feldt-Rasmussen, Bo & Hornum, Mads, 2022, In: Blood Purification. 51, p. 608–616 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    The Glycemic Effect of Liraglutide Evaluated by Continuous Glucose Monitoring in Persons with Type 2 Diabetes Receiving Dialysis

    Bomholt, T., Idorn, T., Knop, Filip Krag, Jørgensen, M. B., Ranjan, A. G., Resuli, M., Hansen, P. M., Borg, Rikke, Persson, F., Feldt-Rasmussen, Bo & Hornum, Mads, 2021, In: Nephron. 145, 1, p. 27-34

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Hemoglobin A1c and Fructosamine Evaluated in Patients with Type 2 Diabetes Receiving Peritoneal Dialysis Using Long-Term Continuous Glucose Monitoring

    Bomholt, T., Feldt-Rasmussen, Bo, Butt, Rizwan Ahmed, Borg, Rikke, Sarwary, M. H., Elung-Jensen, T., Almdal, Thomas Peter, Knop, Filip Krag, Nørgaard, Kirsten, Ranjan, A. G., Larsson, A., Rix, M. & Hornum, Mads, 2022, In: Nephron. 146, 2, p. 146-152

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Genome-wide and caste-specific DNA methylomes of the ants Camponotus floridanus and Harpegnathos saltator

    Bonasio, R., Li, Q., Lian, J., Mutti, N. S., Jin, L., Zhao, H., Zhang, P., Wen, P., Xiang, H., Ding, Y., Jin, Z., Shen, S. S., Wang, Z., Wang, W., Wang, J., Berger, S. L., Liebig, J., KU, thw266 & Reinberg, D., 2012, In: Current Biology. 22, 19, p. 1755-1764 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Reduced postprandial GLP-1 responses in women with gestational diabetes mellitus

    Bonde, L., Vilsbøll, Tina, Nielsen, T., Bagger, J. I., Svare, J. A., Holst, Jens Juul, Larsen, S. & Knop, Filip Krag, 13 Feb 2013, In: Diabetes, Obesity and Metabolism. 15, 8, p. 713-720 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Fasting serum levels of ferritin are associated with impaired pancreatic beta cell function and decreased insulin sensitivity: a population-based study

    Bonfils, L., Ellervik, Christina, Friedrich, N., Linneberg, Allan René, Sandholt, C. H., Jørgensen, M. E., Jørgensen, T., Hansen, Torben, Pedersen, Oluf Borbye & Allin, K. H., 2015, In: Diabetologia. 58, 3, p. 523-533 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Assessing the role of insulin-like growth factors and binding proteins in prostate cancer using Mendelian randomization: Genetic variants as instruments for circulating levels

    Bonilla, C., Lewis, S. J., Rowlands, M-A., Gaunt, T. R., Davey-Smith, G., Gunnell, D., Palmer, T. M., Donovan, J. L., Hamdy, F. C., Neal, D. E., Eeles, R., Easton, D., Kote-Jarai, Z., Al Olama, A. A., Benlloch, S., Muir, K., Giles, G., Wiklund, F., Grönberg, H., Haiman, C. A. & 22 others, Schleutker, J., Nordestgaard, Børge, Travis, R. C., Pashayan, N., Khaw, K., Stanford, J. L., Blot, W. J., Thibodeau, S. N., Maier, C., Kibel, A. S., Cybulski, C., Cannon-Albright, L., Brenner, H., Park, J., Kaneva, R., Batra, J., Teixeira, M. R., Pandha, H., PRACTICAL consortium, P. C., Lathrop, M., Martin, R. M. & Holly, J. M. P., 1 Oct 2016, In: International Journal of Cancer. 139, 7, p. 1520-1533 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Reassessment of the putative role of BLK-p.A71T loss-of-function mutation in MODY and type 2 diabetes

    Bonnefond, A., Yengo, L., Philippe, J., Dechaume, A., Ezzidi, I., Vaillant, E., Gjesing, A. P., Andersson, E. A., Czernichow, S., Hercberg, S., Hadjadj, S., Charpentier, G., Lantieri, O., Balkau, B., Marre, M., Pedersen, Oluf Borbye, Hansen, Torben, Froguel, P. & Vaxillaire, M., Mar 2013, In: Diabetologia. 56, 3, p. 492-496 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    What is the contribution of two genetic variants regulating VEGF levels to type 2 diabetes risk and to microvascular complications?

    Bonnefond, A., Saulnier, P., Stathopoulou, M. G., Grarup, Niels, Ndiaye, N. C., Roussel, R., Nezhad, M. A., Dechaume, A., Lantieri, O., Hercberg, S., Lauritzen, T., Balkau, B., El-Sayed Moustafa, J. S., Hansen, Torben, Pedersen, Oluf Borbye, Froguel, P., Charpentier, G., Marre, M., Hadjadj, S. & Visvikis-Siest, S., Feb 2013, In: P L o S One. 8, 2, p. e55921

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Genetic variant in HK1 is associated with a proanemic state and A1C but not other glycemic control-related traits

    Bonnefond, A., Vaxillaire, M., Labrune, Y., Lecoeur, C., Chèvre, J-C., Bouatia-Naji, N., Cauchi, S., Balkau, B., Marre, M., Tichet, J., Riveline, J-P., Hadjadj, S., Gallois, Y., Czernichow, S., Hercberg, S., Kaakinen, M., Wiesner, S., Charpentier, G., Lévy-Marchal, C., Elliott, P. & 7 others, Jarvelin, M., Horber, F., Dina, C., Pedersen, Oluf Borbye, Sladek, R., Meyre, D. & Froguel, P., 2009, In: Diabetes. 58, 11, p. 2687-97 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes

    Bonàs-Guarch, S., Guindo-Martínez, M., Miguel-Escalada, I., Grarup, N., Sebastian, D., Rodriguez-Fos, E., Sánchez, F., Planas-Fèlix, M., Cortes-Sánchez, P., González, S., Timshel, P., Pers, T. H., Morgan, C. C., Moran, I., Atla, G., González, J. R., Puiggros, M., Martí, J., Andersson, E. A., Díaz, C. & 23 others, Badia, R. M., Udler, M., Leong, A., Kaur, V., Flannick, J., Jørgensen, T., Linneberg, Allan René, Jørgensen, M. E., Witte, D. R., Christensen, C., Brandslund, I., Appel, E. V., Scott, R. A., Luan, J., Langenberg, C., Wareham, N. J., Pedersen, Oluf Borbye, Zorzano, A., Florez, J. C., Hansen, Torben, Ferrer, J., Mercader, J. M. & Torrents, D., 22 Jan 2018, In: Nature Communications. 9, 14 p., 321.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    The Genome of the Netherlands: design, and project goals

    Boomsma, D. I., Wijmenga, C., Slagboom, E. P., Swertz, M. A., Karssen, L. C., Abdellaoui, A., Ye, K., Guryev, V., Vermaat, M., van Dijk, F., Francioli, L. C., Hottenga, J. J., Laros, J. F. J., Li, Q., Li, Y., Cao, H., Chen, R., Du, Y., Li, N., Cao, S. & 32 others, van Setten, J., Menelaou, A., Pulit, S. L., Hehir-Kwa, J. Y., Beekman, M., Elbers, C. C., Byelas, H., de Craen, A. J. M., Deelen, P., Dijkstra, M., den Dunnen, J. T., de Knijff, P., Houwing-Duistermaat, J., Koval, V., Estrada, K., Hofman, A., Kanterakis, A., van Enckevort, D., Mai, H., Kattenberg, M., van Leeuwen, E. M., Neerincx, P. B. T., Oostra, B., Rivadeneira, F., Suchiman, E. H. D., Uitterlinden, A. G., Willemsen, G., Wolffenbuttel, B. H., Wang, J., de Bakker, P. I. W., van Ommen, G. & van Duijn, C. M., 2014, In: European Journal of Human Genetics. 22, p. 221-227 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Abscisic acid controls the release of insulin from beta-cells, Glucagon-Like Peptide-1 from intestinal L-cells and glucagon from alpha-cells

    Booz, V., Christiansen, Charlotte Bayer, Kuhre, Rune Ehrenreich, Saltiel, M. Y., Sturla, L., Sociali, G., Zocchi, E., Holst, Jens Juul & Bruzzone, S., 2017, In: European Journal of Clinical Investigation. 47, p. 112-113

    Research output: Contribution to journalConference abstract in journalResearch

  45. Published

    Abscisic acid stimulates the release of insulin and of GLP-1 in the rat perfused pancreas and intestine

    Booz, V., Christiansen, Charlotte Bayer, Kuhre, Rune Ehrenreich, Saltiel, M. Y., Sociali, G., Schaltenberg, N., Fischer, A. W., Heeren, J., Zocchi, E., Holst, Jens Juul & Bruzzone, S., 2019, In: Diabetes - Metabolism: Research and Reviews (Print Edition). 35, 8 p., e3102.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    HBD-2 mutations are associated with childhood asthma and prophylactic hBD-2 application prevents asthma in mice

    Borchers, N., Santos-Valente, E., Toncheva, A. A., Wehkamp, J., Franke, A., Gaertner, V. D., Nordkild, P., Genuneit, J., Jensen, Benjamin Anderschou Holbech & Kabesch, M., 2021, In: European Respiratory Journal. 58, Suppl. 65, 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Human β-Defensin 2 Mutations Are Associated With Asthma and Atopy in Children and Its Application Prevents Atopic Asthma in a Mouse Model

    Borchers, N. S., Santos-Valente, E., Toncheva, A. A., Wehkamp, J., Franke, A., Gaertner, V. D., Nordkild, P., Genuneit, J., Jensen, Benjamin Anderschou Holbech & Kabesch, M., 2021, In: Frontiers in Immunology. 12, 12 p., 636061.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Mechanism and Binding Site of the ASIC1A-Big Dynorphin Interaction

    Borg, C. B., Braun, N., Heusser, Stephanie, Bay, Y., Weis, D., Galleano, I., Lund, Camilla, Tian, W., Haugaard-Kedstrom, L. M., Bennett, Eric Paul, Lynagh, T., Strømgaard, Kristian, Andersen, J. & Pless, Stephan, 7 Feb 2020, In: Biophysical Journal. 118, 3, supplement 1, p. 582A-582A

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  49. Published

    Mechanism and site of action of big dynorphin on ASIC1a

    Borg, C. B., Braun, N., Heusser, Stephanie, Bay, Y., Weis, D., Galleano, I., Lund, Camilla, Tian, W., Haugaard-Kedström, L. M., Bennett, Eric Paul, Lynagh, T., Strømgaard, Kristian, Andersen, J. & Pless, Stephan, 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 13, p. 7447-7454

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Integrating multiple lines of evidence to assess the effects of maternal BMI on pregnancy and perinatal outcomes

    Borges, M. C., Clayton, G. L., Freathy, R. M., Felix, J. F., Fernández-Sanlés, A., Soares, A. G., Kilpi, F., Yang, Q., McEachan, R. R. C., Richmond, R. C., Liu, X., Skotte, L., Irizar, A., Hattersley, A. T., Bodinier, B., Scholtens, D. M., Nohr, E. A., Bond, T. A., Hayes, M. G., West, J. & 20 others, Tyrrell, J., Wright, J., Bouchard, L., Murcia, M., Bustamante, M., Chadeau-Hyam, M., Jarvelin, M., Vrijheid, M., Perron, P., Magnus, P., Gaillard, R., Jaddoe, V. W. V., Lowe, W. L., Feenstra, B., Hivert, M., Sørensen, Thorkild I.A., Håberg, S. E., Serbert, S., Magnus, M. & Lawlor, D. A., 2024, In: BMC Medicine. 22, 14 p., 32.

    Research output: Contribution to journalJournal articleResearchpeer-review

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