Novo Nordisk Foundation Center for Basic Metabolic Research

G protein-coupled receptor 39 deficiency is associated with pancreatic islet dysfunction

Holst, Birgitte, Egerod, Kristoffer Lihme, Jin, C., Petersen, P. S., Østergaard, M. V., Hald, J., Sprinkel, A. M. E., Størling, J., Mandrup-Poulsen, Thomas, Holst, Jens Juul, Thams, P., Orskov, C., Wierup, N., Sundler, F., Madsen, O. D. & Schwartz, Thue W., 2009, In: Endocrinology. 150, 6, p. 2577-85 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

G-allele of intronic rs10830963 in MTNR1B confers increased risk of impaired fasting glycemia and type 2 diabetes through an impaired glucose-stimulated insulin release: studies involving 19,605 Europeans

Sparsø, T., Bonnefond, A., Andersson, E., Bouatia-Naji, N., Holmkvist, J., Wegner, L., Grarup, N., Gjesing, A. P., Banasik, K., Cavalcanti-Proença, C., Marchand, M., Vaxillaire, M., Charpentier, G., Jarvelin, M-R., Tichet, J., Balkau, B., Marre, M., Lévy-Marchal, C., Faerch, K., Borch-Johnsen, K. & 36 others, Jørgensen, T., Madsbad, Sten, Poulsen, P., Vaag, Allan, Dina, C., Hansen, T., Pedersen, Oluf Borbye, Froguel, P., Sparsø, T., Bonnefond, A., Andersson, E., Bouatia-Naji, N., Holmkvist, J., Wegner, L., Grarup, N., Gjesing, A. P., Banasik, K., Cavalcanti-Proença, C., Marchand, M., Vaxillaire, M., Charpentier, G., Jarvelin, M., Tichet, J., Balkau, B., Marre, M., Lévy-Marchal, C., Faerch, K., Borch-Johnsen, K., Jørgensen, T., Madsbad, Sten, Poulsen, P., Vaag, A., Dina, C., Hansen, T., Pedersen, O. & Froguel, P., 2009, In: Diabetes. 58, 6, p. 1450-6 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Genetic association analysis of 13 nuclear-encoded mitochondrial candidate genes with type II diabetes mellitus: The DAMAGE study

Reiling, E., van Vliet-Ostaptchouk, J. V., van 't Riet, E., van Haeften, T. W., Arp, P. A., Hansen, Torben, Kremer, D., Groenewoud, M. J., van Hove, E. C., Romijn, J. A., Smit, J. W. A., Nijpels, G., Heine, R. J., Uitterlinden, A. G., Pedersen, Oluf Borbye, Slagboom, P. E., Maassen, J. A., Hofker, M. H., 't Hart, L. M. & Dekker, J. M., 2009, In: European Journal of Human Genetics. 17, 8, p. 1056-1062 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Genetic evidence that raised sex hormone binding globulin (SHBG) levels reduce the risk of type 2 diabetes

Perry, J. R. B., Weedon, M. N., Langenberg, C., Jackson, A. U., Lyssenko, V., Sparsø, T., Thorleifsson, G., Grallert, H., Ferrucci, L., Maggio, M., Paolisso, G., Walker, M., Palmer, C. N. A., Payne, F., Young, E., Herder, C., Narisu, N., Morken, M. A., Bonnycastle, L. L., Owen, K. R. & 38 others, Shields, B., Knight, B., Bennett, A., Groves, C. J., Ruokonen, A., Jarvelin, M. R., Pearson, E., Pascoe, L., Ferrannini, E., Bornstein, S. R., Stringham, H. M., Scott, L. J., Kuusisto, J., Nilsson, Carl Martin Peter, Neptin, M., Gjesing, A. P., Pisinger, C., Lauritzen, T., Sandbaek, A., Sampson, M., Zeggini, M. E., Lindgren, C. M., Steinthorsdottir, V., Thorsteinsdottir, U., Hansen, T., Schwarz, Peter, Illig, T., Laakso, M., Stefansson, K., Morris, A. D., Groop, L., Pedersen, Oluf Borbye, Boehnke, M., Barroso, I., Wareham, N. J., Hattersley, A. T., McCarthy, M. I. & Frayling, T. M., 2009, In: Human Molecular Genetics. 19, 3, p. 535-44 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Genetic variant in HK1 is associated with a proanemic state and A1C but not other glycemic control-related traits

Bonnefond, A., Vaxillaire, M., Labrune, Y., Lecoeur, C., Chèvre, J-C., Bouatia-Naji, N., Cauchi, S., Balkau, B., Marre, M., Tichet, J., Riveline, J-P., Hadjadj, S., Gallois, Y., Czernichow, S., Hercberg, S., Kaakinen, M., Wiesner, S., Charpentier, G., Lévy-Marchal, C., Elliott, P. & 7 others, Jarvelin, M., Horber, F., Dina, C., Pedersen, Oluf Borbye, Sladek, R., Meyre, D. & Froguel, P., 2009, In: Diabetes. 58, 11, p. 2687-97 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia

Rung, J., Cauchi, S., Albrechtsen, A., Shen, L., Rocheleau, G., Cavalcanti-Proença, C., Bacot, F., Balkau, B., Belisle, A., Borch-Johnsen, K., Charpentier, G., Dina, C., Durand, E., Elliott, P., Hadjadj, S., Järvelin, M-R., Laitinen, J., Lauritzen, T., Marre, M., Mazur, A. & 20 others, Meyre, D., Montpetit, A., Pisinger, C., Posner, B., Poulsen, P., Pouta, A., Prentki, M., Ribel-Madsen, R., Ruokonen, A., Sandbaek, A., Serre, D., Tichet, J., Vaxillaire, M., Wojtaszewski, Jørgen F P, Vaag, Allan, Hansen, T., Polychronakos, C., Pedersen, Oluf Borbye, Froguel, P. & Sladek, R., 2009, In: Nature Genetics. 41, 10, p. 1110-1115 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity

Thorleifsson, G., Walters, G. B., Gudbjartsson, D. F., Steinthorsdottir, V., Sulem, P., Helgadottir, A., Styrkarsdottir, U., Gretarsdottir, S., Thorlacius, S., Jonsdottir, I., Jonsdottir, T., Olafsdottir, E. J., Olafsdottir, G. H., Jonsson, T., Jonsson, F., Borch-Johnsen, K., Hansen, T., Andersen, G., Jørgensen, T., Lauritzen, T. & 15 others, Aben, K. K., Verbeek, A. L. M., Roeleveld, N., Kampman, E., Yanek, L. R., Becker, L. C., Tryggvadottir, L., Rafnar, T., Becker, D. M., Gulcher, J., Kiemeney, L. A., Pedersen, Oluf Borbye, Kong, A., Thorsteinsdottir, U. & Stefansson, K., 2009, In: Nature Genetics. 41, 1, p. 18-24 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

IDENTIFICATION OF NOVEL VARIANTS IN THE HEPATOCYTE NUCLEAR FACTOR 1 ALPHA GENE IN SOUTH INDIAN PATIENTS WITH MATURITY ONSET DIABETES OF YOUNG

Radha, V., Ek, J., Anuradha, S., Hansen, T., Pedersen, Oluf Borbye & Mohan, V., 2009, In: Journal of Clinical Endocrinology and Metabolism. 6, p. 1959-65

Research output: Contribution to journal › Journal article › Research › peer-review

Identification of novel variants in the hepatocyte nuclear factor-1alpha gene in South Indian patients with maturity onset diabetes of young

Radha, V., Ek, J., Anuradha, S., Hansen, T., Pedersen, Oluf Borbye & Mohan, V., 2009, In: Journal of Clinical Endocrinology and Metabolism. 94, 6, p. 1959-1965 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Identification of the UBP1 locus as a critical blood pressure determinant using a combination of mouse and human genetics

Koutnikova, H., Laakso, M., Lu, L., Combe, R., Paananen, J., Kuulasmaa, T., Kuusisto, J., Häring, H., Hansen, T., Pedersen, Oluf Borbye, Smith, U., Hanefeld, M., Williams, R. W. & Auwerx, J., 2009, In: PLoS Genetics. 5, 8, p. e1000591

Research output: Contribution to journal › Journal article › Research › peer-review

Impaired Insulin-Mediated Phosphorylation of Skeletal Muscle TBC1D4 at Multiple Sites in Type 2 Diabetes. Effect of Endurance Training on TBC1D4 Protein and Phosphorylation

Vind, B. F., Pehmoller, C., Treebak, Jonas Thue, Birk, Jesper Bratz, Hey-Mogensen, M., Beck-Nielsen, H., Wojtaszewski, Jørgen F P & Hojlund, K., 2009, In: Diabetes.

Research output: Contribution to journal › Journal article › Research › peer-review

Insulin gene mutations resulting in early-onset diabetes: marked differences in clinical presentation, metabolic status, and pathogenic effect through endoplasmic reticulum retention

Meur, G., Simon, A., Harun, N., Virally, M., Dechaume, A., Bonnefond, A., Fetita, S., Tarasov, A. I., Guillausseau, P., Boesgaard, T. W., Pedersen, Oluf Borbye, Hansen, T., Polak, M., Gautier, J., Froguel, P., Rutter, G. A. & Vaxillaire, M., 2009, In: Diabetes. 59, 3, p. 653-61 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Intensified multifactorial treatment of patients with Type 2 diabetes: what can be achieved and does it pay off?

Pedersen, Oluf Borbye, 2009, In: Journal of Diabetes. 1, 2, p. 83-9 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Joint analysis of individual participants' data from 17 studies on the association of the IL6 variant -174G >C with circulating glucose levels, interleukin-6 levels, and body mass index.

Huth, C., Illig, T., Herder, C., Gieger, C., Grallert, H., Vollmert, C., Rathmann, W., Hamid, Y., Pedersen, O., Hansen, T., Thorand, B., Meisinger, C., Doring, A., Klopp, N., Gohlke, H., Lieb, W., Hengstenberg, C., Lyssenko, V., Groop, L., Ireland, H. & 16 others, Stephens, J., Wernstedt Asterholm, I., Jansson, J., Boeing, H., Mohlig, M., Stringham, H., Boehnke, M., Tuomilehto, J., Fernandez-Real, J., Lopez-Bermejo, A., Gallart, L., Vendrell, J., Humphries, S., Kronenberg, F., Wichmann, H. & Heid, I., 2009, In: Annals of Medicine. 41, p. 128-38

Research output: Contribution to journal › Journal article › Research › peer-review

Joint analysis of individual participants' data from 17 studies on the association of the IL6 variant -174G>C with circulating glucose levels, interleukin-6 levels, and body mass index

Huth, C., Illig, T., Herder, C., Gieger, C., Grallert, H., Vollmert, C., Rathmann, W., Hamid, Y. H., Pedersen, O., Hansen, T., Thorand, B., Meisinger, C., Doring, A., Klopp, N., Gohlke, H., Lieb, W., Hengstenberg, C., Lyssenko, V., Groop, L., Ireland, H. & 16 others, Stephens, J. W., Asterholm, I. W., Jansson, J. O., Boeing, H., Mohlig, M., Stringham, H. M., Boehnke, M., Tuomilehto, J., Fernandez-Real, J. M., Lopez-Bermejo, A., Gallart, L., Vendrell, J., Humphries, S. E., Kronenberg, F., Wichmann, H. E. & Heid, I. M., 2009, In: Annals of Medicine. 41, 2, p. 128-138 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Long-term exendin-4 treatment delays natural deterioration of glycaemic control in diabetic Goto-Kakizaki rats

Simonsen, L., Pilgaard, S., Orskov, C., Hartmann, Bolette, Holst, Jens Juul & Deacon, Carolyn F., 2009, In: Diabetes, Obesity and Metabolism. 11, 9, p. 884-90 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Longitudinal Analysis of Leptin Variation during Weight Regain after Weight Loss in Obese Children

Holm, Jens-Christian, Gamborg, Michael Orland, Leigh, W., Kaas, I. K., Ibsen, G., Sørensen, Thorkild I.A., Lilienthal, H. B., Holm, Jens-Christian, Gamborg, M., Ward, L., Ibsen, K. K., Gammeltoft, S., Sørensen, Thorkild I.A. & Heitmann, B. L., 2009, In: Obesity Facts. 2, 4, p. 243-248 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Mitochondrial function in lamb as a consequence of maternal caloric restriction during pregnancy and high-fat-high-carbohydrate diet post partem

Jørgensen, W., Nielsen, M. O., Gam, C., Scheibye-Knudsen, M., Grunnet, N. & Quistorff, B., 2009, In: Journal of Diabetes. 1, Suppl. 1, p. A81 1 p.

Research output: Contribution to journal › Conference abstract in journal › Research

Mutations in the VNTR of the carboxyl-ester lipase gene (CEL) are a rare cause of monogenic diabetes

Torsvik, J., Johansson, S., Johansen, A., Ek, J., Minton, J., Raeder, H., Ellard, S., Hattersley, A., Pedersen, Oluf Borbye, Hansen, T., Molven, A. & Njølstad, P. R., 2009, In: Human Genetics. 127, 1, p. 55-64 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

No consistent effect of ADRB2 haplotypes on obesity, hypertension and quantitative traits of body fatness and blood pressure among 6,514 adult Danes

Gjesing, A. P., Sparsø, T., Borch-Johnsen, K., Jørgensen, T., Pedersen, Oluf Borbye, Hansen, T. & Olsen, N. V., 2009, In: PLoS ONE. 4, 9, p. e7206

Research output: Contribution to journal › Journal article › Research › peer-review

Past and current body size affect validity of reported energy intake among middle-aged Danish men

Nielsen, B. M., Nielsen, M. M., Toubro, S., Pedersen, Oluf Borbye, Astrup, A., Sørensen, Thorkild I.A., Jess, T. & Heitmann, B. L., 2009, In: Journal of Nutrition. 139, 12, p. 2337-2343 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Polymorphisms of serotonin receptor 2A and 2C genes and COMT in relation to obesity and type 2 diabetes

Kring, S. I. I., Werge, Thomas, Holst, C., Toubro, S., Astrup, A., Hansen, Torben, Pedersen, Oluf Borbye & Sørensen, Thorkild I.A., 2009, In: PLoS ONE. 4, 8, p. e6696 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Predictive performance for population models using stochastic differential equations applied on data from an oral glucose tolerance test

Møller, J. B., Overgaard, R. V., Madsen, H., Hansen, T., Pedersen, Oluf Borbye & Ingwersen, S. H., 2009, In: Journal of Pharmacokinetics and Pharmacodynamics. 37, 1, p. 85-98 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Predictors of future fasting and 2-h post-OGTT plasma glucose levels in middle-aged men and women-the Inter99 study

Faerch, K., Vaag, Allan, Witte, D. R., Jørgensen, T., Pedersen, Oluf Borbye & Borch-Johnsen, K., 2009, In: Diabetic Medicine. 26, 4, p. 377-83 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Progression to impaired glucose regulation and diabetes in the population-based Inter99 study

Engberg, S., Vistisen, D., Lau, C., Glümer, C., Jørgensen, T., Pedersen, Oluf Borbye & Borch-Johnsen, K., 2009, In: Diabetes Care. 32, p. 606-11

Research output: Contribution to journal › Journal article › Research › peer-review

Spaedbørnsdiabetes kan ofte behandles med sulfonylurinstof i stedet for insulin

Lauridsen, M. H., Boesgaard, T. W., Pedersen, Oluf Borbye, Hansen, T. & Hertz, B., 2009, In: Ugeskrift for læger. 171, 23, p. 1923-4 1 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Studies of CTNNBL1 and FDFT1 variants and measures of obesity: analyses of quantitative traits and case-control studies in 18,014 Danes

Andreasen, C. H., Mogensen, M. S., Borch-Johnsen, K., Sandbaek, A., Lauritzen, T., Almind, K., Hansen, L., Jørgensen, T., Pedersen, Oluf Borbye & Hansen, Torben, 2009, In: BMC Medical Genetics. 10, 1, p. 17

Research output: Contribution to journal › Journal article › Research › peer-review

The type 2 diabetes associated minor allele of rs2237895 KCNQ1 associates with reduced insulin release following an oral glucose load

Holmkvist, J., Banasik, K., Andersen, G., Unoki, H., Jensen, T. S., Pisinger, C., Borch-Johnsen, K., Sandbaek, A., Lauritzen, T., Brunak, Søren, Maeda, S., Hansen, T. & Pedersen, Oluf Borbye, 2009, In: PLoS ONE. 4, 6, p. e5872

Research output: Contribution to journal › Journal article › Research › peer-review

Validation of a multimarker model for assessing risk of type 2 diabetes from a five-year prospective study of 6784 Danish people (Inter99)

Urdea, M., Kolberg, J., Wilber, J., Gerwien, R., Moler, E., Rowe, M., Jorgensen, P., Hansen, T., Pedersen, Oluf Borbye, Jørgensen, T. & Borch-Johnsen, K., 2009, In: Journal of Diabetes Science and Technology. 3, 4, p. 748-55 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Variant near ADAMTS9 known to associate with type 2 diabetes is related to insulin resistance in offspring of type 2 diabetes patients--EUGENE2 study

Boesgaard, T. W., Gjesing, A. P., Grarup, N., Rutanen, J., Jansson, P., Hribal, M. L., Sesti, G., Fritsche, A., Stefan, N., Staiger, H., Häring, H., Smith, U., Laakso, M., Pedersen, Oluf Borbye, Hansen, T. & EUGENE2 Consortium, E. C., 2009, In: PLoS ONE. 4, 9, p. e7236

Research output: Contribution to journal › Journal article › Research › peer-review

Variants near MC4R associate with obesity and influence obesity-related quantitative traits in a population of middle-aged people: studies of 14,940 Danes

Zobel, D. P., Andreasen, C. H., Grarup, N., Eiberg, Hans Rudolf Lytchoff, Sørensen, Thorkild I.A., Sandbæk, A., Lauritzen, T., Borch-Johnsen, K., Jørgensen, T., Pedersen, Oluf Borbye & Hansen, T., 2009, In: Diabetes. p. 757-764 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Variation in CHI3LI in relation to type 2 diabetes and related quantitative traits

Rathcke, C. N., Holmkvist, J., Jørgensen, T., Borch-Johnsen, K., Hansen, T., Pedersen, Oluf Borbye & drb459, drb459, 2009, In: PLoS ONE. 4, 5, p. e5469

Research output: Contribution to journal › Journal article › Research › peer-review

Variation in the gene encoding Kruppel-like factor 7 influences body fat: studies of 14,818 Danes

Zobel, D., Andreasen, C., Burgdorf, K., Andersson, E., Sandbæk, A., Lauritzen, T., Borch-Johnsen, K., Jørgensen, T., Maeda, S., Nakamura, Y., Eiberg, Hans Rudolf Lytchoff, Pedersen, Oluf Borbye & Hansen, Torben, 2009, In: European Journal of Endocrinology. 160, 4, p. 603-9

Research output: Contribution to journal › Journal article › Research › peer-review

Common variant in MTNR1B associated with increased risk of type 2 diabetes and impaired early insulin secretion

Lyssenko, V., Nagorny, C. L. F., Erdos, M. R., Wierup, N., Jonsson, A. E., Spégel, P., Bugliani, M., Saxena, R., Fex, M., Pulizzi, N., Isomaa, B., Tuomi, T., Nilsson, P., Kuusisto, J., Tuomilehto, J., Boehnke, M., Altshuler, D., Sundler, F., Eriksson, J. G., Jackson, A. U. & 5 others, Laakso, M., Marchetti, P., Watanabe, R. M., Mulder, H. & Groop, L., Jan 2009, In: Nature Genetics. 41, 1, p. 82-8 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Genotype phenotype correlations of cardiac beta-myosin heavy chain mutations in Indian patients with hypertrophic and dilated cardiomyopathy

Rai, T. S., Ahmad, S., Bahl, A., Ahuja, M., Ahluwalia, Tarun Veer Singh, Singh, B., Talwar, K. K. & Khullar, M., Jan 2009, In: Molecular and Celluar Biochemistry. 321, 1-2, p. 189-96 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Common type 2 diabetes risk gene variants associate with gestational diabetes

Lauenborg, J., Grarup, N., Damm, Peter, Borch-Johnsen, K., Jørgensen, T., Pedersen, Oluf Borbye, Hansen, T., Lauenborg, J., Grarup, N., Damm, Peter, Borch-Johnsen, K., Jørgensen, T., Pedersen, O. & Hansen, T., 1 Jan 2009, In: Journal of Clinical Endocrinology and Metabolism. 94, 1, p. 145-50 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Concurrent regulation of AMP-activated protein kinase and SIRT1 in mammalian cells

Suchankova, G., Nelson, L. E., Gerhart-Hines, Zach, Kelly, M., Gauthier, M. S., Saha, A. K., Ido, Y., Puigserver, P. & Ruderman, N. B., 23 Jan 2009, In: Biochemical and Biophysical Research Communications. 378, 4, p. 836-841 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

ACE variants interact with the RAS pathway to confer risk and protection against type 2 diabetic nephropathy

Ahluwalia, Tarun Veer Singh, Ahuja, M., Rai, T. S., Kohli, H. S., Bhansali, A., Sud, K. & Khullar, M., Mar 2009, In: D N A and Cell Biology. 28, 3, p. 141-50 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Synaptotagmin-7 is a principal Ca2+ sensor for Ca2+ -induced glucagon exocytosis in pancreas

Gustavsson, N., Wei, S., Hoang, D. N., Lao, Y., Zhang, Q., Radda, G. K., Rorsman, P., Südhof, T. C. & Han, W., 15 Mar 2009, In: The Journal of Physiology. 587, Pt 6, p. 1169-78 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Obesity, FTO gene variant, and energy intake in children

Jonsson, Anna Elisabet & Franks, P. W., 9 Apr 2009, In: New England Journal of Medicine. 360, 15, p. 1571-2; author reply 1572

Research output: Contribution to journal › Journal article › Research

AMPK regulates energy expenditure by modulating NAD + metabolism and SIRT1 activity

Cantó, C., Gerhart-Hines, Zach, Feige, J. N., Lagouge, M., Noriega, L., Milne, J. C., Elliott, P. J., Puigserver, P. & Auwerx, J., 23 Apr 2009, In: Nature. 458, 7241, p. 1056-1060 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Interaction between prenatal growth and high-risk genotypes in the development of type 2 diabetes

Pulizzi, N., Lyssenko, V., Jonsson, Anna Elisabet, Osmond, C., Laakso, M., Kajantie, E., Barker, D. J., Groop, L. C. & Eriksson, J. G., May 2009, In: Diabetologia. 52, 5, p. 825-9 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Unique splicing pattern of the TCF7L2 gene in human pancreatic islets

Osmark, P., Hansson, O., Jonsson, Anna Elisabet, Rönn, T., Groop, L. & Renström, E., May 2009, In: Diabetologia. 52, 5, p. 850-4 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Altered expression and insulin-induced trafficking of Na+-K+-ATPase in rat skeletal muscle: effects of high-fat diet and exercise

Galuska, D., Kotova, O., Barrès, Romain, Chibalina, D., Benziane, B. & Chibalin, A. V., Jul 2009, In: A J P: Endocrinology and Metabolism (Online). 297, 1, p. E38-49

Research output: Contribution to journal › Journal article › Research › peer-review

Assessing the effect of interaction between an FTO variant (rs9939609) and physical activity on obesity in 15,925 Swedish and 2,511 Finnish adults

Jonsson, Anna Elisabet, Renström, F., Lyssenko, V., Brito, E. C., Isomaa, B., Berglund, G., Nilsson, P., Groop, L. & Franks, P. W., Jul 2009, In: Diabetologia. 52, 7, p. 1334-8 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Pairagon: a highly accurate, HMM-based cDNA-to-genome aligner.

Lu, D. V., Brown, R. H., Arumugam, Mani & Brent, M. R., Jul 2009, In: Bioinformatics. 25, 13, p. 1587-1593 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Overweight and the metabolic syndrome in adult offspring of women with diet-treated gestational diabetes mellitus or type 1 diabetes

Clausen, Tine Dalsgaard, Mathiesen, E. R., Hansen, T., Pedersen, Oluf Borbye, Jensen, D. M., Lauenborg, J., Schmidt, Lone, Damm, Peter, Clausen, T. D., Mathiesen, Elisabeth, Hansen, T., Pedersen, O., Jensen, D., Lauenborg, J., Schmidt, L. & Damm, Peter, 1 Jul 2009, In: Journal of Clinical Endocrinology and Metabolism. 94, 7, p. 2464-70 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The T allele of rs7903146 TCF7L2 is associated with impaired insulinotropic action of incretin hormones, reduced 24 h profiles of plasma insulin and glucagon, and increased hepatic glucose production in young healthy men

Pilgaard, K., Jensen, C., Schou, J., Lyssenko, V., Wegner, L., Brøns, C., Vilsbøll, T., Hansen, T., Madsbad, S., Holst, J., Vølund, A., Poulsen, P., Groop, L., Pedersen, O., Vaag, A., Pilgaard, K., Jensen, C. B., Schou, J. H., Lyssenko, V., Wegner, L. & 10 others, Brøns, C., Vilsbøll, T., Hansen, T., Madsbad, Sten, Holst, J. M., Vølund, A., Poulsen, P., Groop, L., Pedersen, O. & Vaag, A., 1 Jul 2009, In: Diabetologia. 52, 7, p. 1298-307 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Calcium-sensing beyond neurotransmitters: functions of synaptotagmins in neuroendocrine and endocrine secretion

Gustavsson, N. & Han, W., Aug 2009, In: Bioscience Reports. 29, 4, p. 245-59 15 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Non-CpG methylation of the PGC-1alpha promoter through DNMT3B controls mitochondrial density

Barrès, Romain, Osler, M. E., Yan, J., Rune, A., Fritz, T., Caidahl, K., Krook, A. & Zierath, Juleen R, Sep 2009, In: Cell Metabolism. 10, 3, p. 189-98 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment

Schafer, Z. T., Grassian, A. R., Song, L., Jiang, Z., Gerhart-Hines, Zach, Irie, H. Y., Gao, S., Puigserver, P. & Brugge, J. S., 3 Sep 2009, In: Nature. 461, 7260, p. 109-113 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Peroxisome proliferator-activated receptor gamma regulates expression of the anti-lipolytic G-protein-coupled receptor 81 (GPR81/Gpr81)

Jeninga, E. H., Bugge, A. S., Nielsen, R., Kersten, S., Hamers, N., Dani, C., Wabitsch, M., Berger, R., Stunnenberg, H. G., Mandrup, S. & Kalkhoven, E., 25 Sep 2009, In: The Journal of Biological Chemistry. 284, 39, p. 26385-93 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

A variant in the KCNQ1 gene predicts future type 2 diabetes and mediates impaired insulin secretion

Jonsson, Anna Elisabet, Isomaa, B., Tuomi, T., Taneera, J., Salehi, A., Nilsson, P., Groop, L. & Lyssenko, V., Oct 2009, In: Diabetes. 58, 10, p. 2409-13 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Genetic and clinical profile of Indian patients of idiopathic restrictive cardiomyopathy with and without hypertrophy

Rai, T. S., Ahmad, S., Ahluwalia, Tarun Veer Singh, Ahuja, M., Bahl, A., Saikia, U. N., Singh, B., Talwar, K. K. & Khullar, M., Nov 2009, In: Developments in Molecular and Cellular Biochemistry. 331, 1-2, p. 187-92 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Transcriptome complexity in a genome-reduced bacterium.

Güell, M., van Noort, V., Yus, E., Chen, W., Leigh-Bell, J., Michalodimitrakis, K., Yamada, T., Arumugam, Mani, Doerks, T., Kühner, S., Rode, M., Suyama, M., Schmidt, S., Gavin, A., Bork, P. & Serrano, L., Nov 2009, In: Science. 326, 5957, p. 1268-1271 4 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Role of the AMPKgamma3 isoform in hypoxia-stimulated glucose transport in glycolytic skeletal muscle

Deshmukh, Atul Shahaji, Glund, S., Tom, R. Z. & Zierath, Juleen R, Dec 2009, In: American Journal of Physiology: Endocrinology and Metabolism. 297, 6, p. E1388-94

Research output: Contribution to journal › Journal article › Research › peer-review

ZBED6, a novel transcription factor derived from a domesticated DNA transposon regulates IGF2 expression and muscle growth

Markljung, E., Jiang, L., Jaffe, J. D., Mikkelsen, T. S., Wallerman, O., Larhammar, M., Zhang, X., Wang, L., Saenz-Vash, V., Gnirke, A., Lindroth, A. M., Barres, R., Yan, J., Strömberg, S., De, S., Pontén, F., Lander, E. S., Carr, S. A., Zierath, J. R., Kullander, K. & 5 others, Wadelius, C., Lindblad-Toh, K., Andersson, G., Hjälm, G. & Andersson, L., Dec 2009, In: P L o S Biology (Online). 7, 12, p. e1000256

Research output: Contribution to journal › Journal article › Research › peer-review

TCF7L2 rs7903146-macronutrient interaction in obese individuals' responses to a 10-wk randomized hypoenergetic diet

Grau, K., Cauchi, S., Holst, C., Astrup, A., Martinez, J. A., Saris, W. H. M., Blaak, E. E., Oppert, J., Arner, P., Rössner, S., Macdonald, I. A., Klimcakova, E., Langin, D., Pedersen, Oluf Borbye, Froguel, P. & Sørensen, Thorkild I.A., 2010, In: American Journal of Clinical Nutrition. 91, 2, p. 472-479 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

A conserved aromatic lock for the tryptophan rotameric switch in TM-VI of seven-transmembrane receptors

Holst, Birgitte, Nygaard, R., Hansen, L. V., Bach, Anders, Engelstoft, M. S., Petersen, P. S., Frimurer, T. M. & Schwartz, Thue W., 2010, In: Journal of Biological Chemistry. 285, 6, p. 3973-85 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

A human gut microbial gene catalogue established by metagenomic sequencing

MetaHIT Consortium, M. C., 2010, In: Nature. 464, 7285, p. 59-65 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Bed Rest-Induced Changes in TBC1D4 Phosphorylation and Glycogen Synthase Activity. Effects of Acute Exercise

Bienso, R. S., Ringholm, S., Lundby, C., Achman-Andersen, N. J., Plomgaard, Peter Stendahl, Krogh-Madsen, Rikke, Kiilerich, K., Guerra, B., Treebak, Jonas Thue, Calbet, J. A., Pilegaard, Henriette & Wojtaszewski, J. J. F., 2010, In: Diabetes.

Research output: Contribution to journal › Journal article › Research › peer-review

Brain nonoxidative carbohydrate consumption is not explained by export of an unknown carbon source: evaluation of the arterial and jugular venous metabolome

Rasmussen, P., Nyberg, N., Jaroszewski, J. W., Krogh-Madsen, Rikke, Secher, Niels H. & Quistorff, B., 2010, In: Journal of Cerebral Blood Flow and Metabolism. 30, 6, p. 1240-1246

Research output: Contribution to journal › Journal article › Research › peer-review

Combined Analyses of 20 Common Obesity Susceptibility Variants

Sandholt, C. H., Sparsø, T., Grarup, Niels, Albrechtsen, Anders, Almind, K., Hansen, L., Toft, U., Jørgensen, T., Hansen, Torben & Pedersen, Oluf Borbye, 2010, In: Diabetes. 59, 7, p. 1667-1673 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Combined effects of weight loss and physical activity on all-cause mortality of overweight men and women

ÿstergaard, J. N., Grønbaek, M., Schnohr, P., Sørensen, Thorkild I.A. & Heitmann, Berit, 2010, In: International Journal of Obesity. 34, 4, p. 760-9 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Common variants near MC4R in relation to body fat, body fat distribution, metabolic traits and energy expenditure

Kring, S. I. I., Holst, C., Toubro, S., Astrup, A., Hansen, T., Pedersen, Oluf Borbye & Sørensen, Thorkild I.A., 2010, In: International Journal of Obesity. 34, 1, p. 182-189 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Common variants near MC4R in relation to body fat, body fat distribution, metabolic traits and energy expenditure

Kring, S. I. I., Holst, C., Toubro, S., Astrup, A., Hansen, T., Pedersen, Oluf Borbye & Sørensen, Thorkild I.A., 2010, In: International Journal of Obesity. 34, 1, p. 182-9 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Conserved water-mediated hydrogen bond network between TM-I, -II, -VI, and -VII in 7TM receptor activation

Nygaard, R., Hansen, L. V., Mokrosinski, J., Frimurer, T. M. & Schwartz, Thue W., 2010, In: Journal of Biological Chemistry. 285, 25, p. 19625-36 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Design of association studies with pooled or un-pooled next-generation sequencing data

Kim, S. Y., Li, Y., Guo, Y., Li, R., Holmkvist, J., Hansen, Torben, Pedersen, Oluf Borbye, Wang, J. & Nielsen, Rasmus, 2010, In: Genetic Epidemiology. 34, 5, p. 479-491 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Differential aetiology and impact of phosphoinositide 3-kinase (PI3K) and Akt signalling in skeletal muscle on in vivo insulin action

Friedrichsen, M., Poulsen, P., Richter, Erik A., Hansen, B. F., Birk, Jesper Bratz, Ribel-Madsen, R., Stender-Petersen, K., Nilsson, E., Beck-Nielsen, H., Vaag, Allan & Wojtaszewski, Jørgen F P, 2010, In: Diabetologia. 53, 9, p. 1998-2007 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Do things talk?

Söderqvist, Thomas & Bencard, Adam, 2010, In: Max Planck Institute for History of Science, Preprint Series. 399, p. 92-102 11 p.

Research output: Contribution to journal › Conference article › Research › peer-review

Effects of Exercise on Lipid-Induced Insulin Resistance in Human Skeletal Muscle-Signaling at the Level of TBC1D4

Pehmoller, C., Brandt, N., Birk, Jesper Bratz, Treebak, Jonas Thue, Hoeg, L. D., Sjoberg, K. A., Kiens, Bente, Richter, Erik A. & Wojtaszewski, Jørgen F P, 2010, In: Diabetes.

Research output: Contribution to journal › Journal article › Research › peer-review

Effects of category-specific costs on neural systems for perceptual decision-making

Fleming, S. M., Whiteley, Louise, Hulme, O. J., Sahani, M. & Dolan, R. J., 2010, In: Journal of Neurology & Neurophysiology. 103, 6, p. 3238-47 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Family and population-based studies of variation within the ghrelin receptor locus in relation to measures of obesity

Gjesing, A. P., Larsen, L. H., Torekov, S. S., Hainerová, I. A., Kapur, R., Johansen, A., Albrechtsen, A., Boj, S., Holst, B., Harper, A., Urhammer, S. A., Borch-Johnsen, K., Pisinger, C. H., Echwald, S. M., Eiberg, H. R. L., Astrup, A., Lebl, J., Ferrer, J., Schwartz, T. W., Hansen, T. & 1 others, Pedersen, Oluf Borbye, 2010, In: P L o S One. 5, 4, 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

HDACs class II-selective inhibition alters nuclear receptor-dependent differentiation

Nebbioso, A., Dell'Aversana, C., Bugge, A. S., Sarno, R., Valente, S., Rotili, D., Manzo, F., Teti, D., Mandrup, S., Ciana, P., Maggi, A., Mai, A., Gronemeyer, H. & Altucci, L., 2010, In: Journal of Molecular Endocrinology. 45, 4, p. 219-28 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Identification of KCNJ15 as a susceptibility gene in Asian patients with type 2 diabetes mellitus

Okamoto, K., Iwasaki, N., Nishimura, C., Doi, K., Noiri, E., Nakamura, S., Takizawa, M., Ogata, M., Fujimaki, R., Grarup, N., Pisinger, C., Borch-Johnsen, K., Lauritzen, T., Sandbaek, A., Hansen, T., Yasuda, K., Osawa, H., Nanjo, K., Kadowaki, T., Kasuga, M. & 5 others, Pedersen, Oluf Borbye, Fujita, T., Kamatani, N., Iwamoto, Y. & Tokunaga, K., 2010, In: American Journal of Human Genetics. 86, 1, p. 54-64 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Impact of rs361072 in the phosphoinositide 3-kinase p110beta gene on whole-body glucose metabolism and subunit protein expression in skeletal muscle

Ribel-Madsen, R., Poulsen, P., Holmkvist, J., Mortensen, B., Grarup, Niels, Friedrichsen, M., Jørgensen, T., Lauritzen, T., Wojtaszewski, Jørgen F P, Pedersen, Oluf Borbye, Hansen, Torben & Vaag, Allan, 2010, In: Diabetes. 59, 4, p. 1108-1112 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Impact of size at birth and prematurity on adult anthropometry in 4744 middle-aged Danes - The Inter99 Study

Pilgaard, K., Færch, K., Poulsen, P., Larsen, C., Andersson, E. A., Pisinger, C. H., Toft, U., Aadahl, M., Pedersen, Oluf Borbye, Hansen, Torben, Jørgensen, T., Borch-Johnsen, K. & Vaag, Allan, 2010, In: Journal of Developmental Origins of Health and Disease. 1, 5, p. 319-328 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

MTNR1B G24E variant associates With BMI and fasting plasma glucose in the general population in studies of 22,142 Europeans

Andersson, E. A., Holst, Birgitte, Sparsø, T., Grarup, Niels, Banasik, Karina, Holmkvist, J., Jørgensen, T., Borch-Johnsen, K., Egerod, Kristoffer Lihme, Lauritzen, T., Sørensen, Thorkild I.A., Bonnefond, A., Meyre, D., Froguel, P., Schwartz, Thue W., Pedersen, Oluf Borbye & Hansen, Torben, 2010, In: Diabetes. 59, 6, p. 1539-48 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Molecular Mechanisms and Genome-Wide Aspects of PPAR Subtype Specific Transactivation

Bugge, A. S. & Mandrup, S., 2010, In: PPAR Research. 2010

Research output: Contribution to journal › Journal article › Research › peer-review

Neuroscience evidence should be incorporated into our ethical practices

Felsen, G., Whiteley, Louise, Nadler, R. & Reiner, P. B., 2010, In: A J O B Neuroscience. 1, 4, p. 36-38

Research output: Contribution to journal › Comment/debate › Communication

Obesity-related polymorphisms and their associations with the ability to regulate fat oxidation in obese europeans: The NUGENOB Study

Corpeleijn, E., Petersen, L., Holst, C., Saris, W. H., Astrup, A., Langin, D., Macdonald, I., Martinez, J. A., Oppert, J., Polak, J., Pedersen, Oluf Borbye, Froguel, P., Arner, P., Sørensen, Thorkild I.A. & Blaak, E. E., 2010, In: Obesity. 18, 7, p. 1369-1377 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Resequencing of 200 human exomes identifies an excess of low-frequency non-synonymous coding variants

Li, Y., Vinckenbosch, N., Tian, G., Huerta-Sanchez, E., Jiang, T., Jiang, H., Albrechtsen, A., Andersen, G., Cao, H., Korneliussen, T. S., Grarup, N., Guo, Y., Hellman, I., Jin, X., Li, Q., Liu, J., Liu, X., Sparsø, T., Tang, M., Wu, H. & 18 others, Wu, R., Yu, C., Zheng, H., Astrup, A., Bolund, L., Holmkvist, J., Jørgensen, T., Kristiansen, Karsten, Schmitz, O., Schwartz, Thue W., Zhang, X., Li, R., Yang, H., Wang, J., Hansen, Torben, Pedersen, Oluf Borbye, Nielsen, Rasmus & Wang, J., 2010, In: Nature Genetics. 42, 11, p. 969-72 4 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Spatially distributed encoding of covert attentional shifts in human thalamus

Hulme, O. J., Whiteley, Louise & Shipp, S., 2010, In: Journal of Neurology & Neurophysiology. 104, 6, p. 3644-56 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The T-allele of TCF7L2 rs7903146 associates with a reduced compensation of insulin secretion for insulin resistance induced by 9 days of bed rest

Alibegovic, A. C., Sonne, M. P., Højbjerre, L., Hansen, T., Pedersen, Oluf Borbye, van Hall, Gerrit, Holst, Jens Juul, Stallknecht, Bente Merete, Dela, Flemming & Vaag, A., 2010, In: Diabetes. 59, 4, p. 836-43 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

A single nucleotide polymorphism within the acetyl-coenzyme A carboxylase beta gene is associated with proteinuria in patients with type 2 diabetes

Maeda, S., Kobayashi, M., Araki, S., Babazono, T., Freedman, B. I., Bostrom, M. A., Cooke, J. N., Toyoda, M., Umezono, T., Tarnow, L., Hansen, T., Gaede, P., Jorsal, A., Ng, D. P. K., Ikeda, M., Yanagimoto, T., Tsunoda, T., Unoki, H., Kawai, K., Imanishi, M. & 11 others, Suzuki, D., Shin, H. D., Park, K. S., Kashiwagi, A., Iwamoto, Y., Kaku, K., Kawamori, R., Parving, H., Bowden, D. W., Pedersen, Oluf Borbye & Nakamura, Y., 1 Jan 2010, In: P L o S Genetics. 6, 2, p. e1000842

Research output: Contribution to journal › Journal article › Research › peer-review

Advancing the future of physical activity guidelines in Canada: an independent expert panel interpretation of the evidence

Kesäniemi, A., Riddoch, C. J., Reeder, B., Blair, S. N. & Sørensen, Thorkild I.A., 1 Jan 2010, In: International Journal of Behavioral Nutrition and Physical Activity. 7, p. 41

Research output: Contribution to journal › Journal article › Research › peer-review

Birth weight, childhood body mass index and risk of coronary heart disease in adults: combined historical cohort studies

Andersen, L. G., Ängquist, Lars, Eriksson, J. G., Forsen, T., Gamborg, Michael Orland, Osmond, C., Baker, J. L. & Sørensen, Thorkild I.A., 1 Jan 2010, In: P L o S One. 5, 11, p. e14126

Research output: Contribution to journal › Journal article › Research › peer-review

Changes in waist circumference and mortality in middle-aged men and women

Berentzen, T. L., Jakobsen, M. U., Halkjaer, J., Tjønneland, A., Overvad, K. & Sørensen, Thorkild I.A., 1 Jan 2010, In: P L o S One. 5, 9

Research output: Contribution to journal › Journal article › Research › peer-review

Dietary determinants of changes in waist circumference adjusted for body mass index - a proxy measure of visceral adiposity

Romaguera, D., Ängquist, Lars, Du, H., Jakobsen, M. U., Forouhi, N. G., Halkjaer, J., Feskens, E. J. M., van der A, D. L., Masala, G., Steffen, A., Palli, D., Wareham, N. J., Overvad, K., Tjønneland, A., Boeing, H., Riboli, E. & Sørensen, Thorkild I.A., 1 Jan 2010, In: P L o S One. 5, 7, p. e11588

Research output: Contribution to journal › Journal article › Research › peer-review

Do gene variants influencing adult adiposity affect birth weight? A population-based study of 24 loci in 4,744 Danish individuals

Andersson, E. A., Pilgaard, K., Pisinger, C., Harder, M. N., Grarup, Niels, Færch, K., Sandholt, C., Poulsen, P., Witte, D. R., Jørgensen, T., Vaag, Allan, Pedersen, Oluf Borbye & Hansen, T., 1 Jan 2010, In: P L o S One. 5, 12, p. e14190

Research output: Contribution to journal › Journal article › Research › peer-review

Further evidence that mutations in INS can be a rare cause of Maturity-Onset Diabetes of the Young (MODY)

Boesgaard, T. W., Pruhova, S., Andersson, E. A., Cinek, O., Obermannova, B., Lauenborg, J., Damm, Peter, Bergholdt, R., Pociot, Flemming, Pisinger, C., Barbetti, F., Lebl, J., Pedersen, Oluf Borbye & Hansen, Torben, 1 Jan 2010, In: B M C Medical Genetics. 11, p. 42

Research output: Contribution to journal › Journal article › Research › peer-review

Genetic determinants of both ethanol and acetaldehyde metabolism influence alcohol hypersensitivity and drinking behaviour among Scandinavians

Linneberg, Allan René, Gonzalez-Quintela, A., Vidal, C., Jørgensen, T., Fenger, M., Hansen, Torben, Pedersen, Oluf Borbye & Husemoen, L. L. N., 1 Jan 2010, In: Clinical and Experimental Allergy. 40, 1, p. 123-30 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Genetic influences on incidence and case-fatality of infectious disease

Petersen, L., Andersen, Per Kragh & Sørensen, Thorkild I.A., 1 Jan 2010, In: P L o S One. 5, 5, p. e10603

Research output: Contribution to journal › Journal article › Research › peer-review

Gestational protein restriction in mice has pronounced effects on gene expression in newborn offspring's liver and skeletal muscle; protective effect of taurine

Mortensen, Ole Hartvig, Olsen, H. L., Frandsen, L., Nielsen, Peter E., Nielsen, Finn Cilius, Grunnet, N., Quistorff, B., Mortensen, O. H., Olsen, H. L., Frandsen, L., Nielsen, P. E., Nielsen, Finn Cilius, Grunnet, N. & Quistorff, B., 1 Jan 2010, In: Pediatric Research. 67, 1, p. 47-53 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Maternal postpartum distress and childhood overweight

Adeltoft, T. A., Andersen, C. S., Ingstrup, K. G., Nohr, E. A., Sørensen, Thorkild I.A. & Sørensen, Thorkild I.A., 1 Jan 2010, In: P L o S One. 5, 6, p. e11136

Research output: Contribution to journal › Journal article › Research › peer-review

Prenatal stress exposure related to maternal bereavement and risk of childhood overweight

Li, J., Olsen, J., Vestergaard, M., Obel, C., Baker, J. L. & Sørensen, Thorkild I.A., 1 Jan 2010, In: P L o S One. 5, 7, p. e11896

Research output: Contribution to journal › Journal article › Research › peer-review

The association of alcohol and alcohol metabolizing gene variants with diabetes and coronary heart disease risk factors in a white population

Husemoen, L. L. N., Jørgensen, T., Borch-Johnsen, K., Hansen, Torben, Pedersen, Oluf Borbye & Linneberg, Allan René, 1 Jan 2010, In: P L o S One. 5, 8, p. e11735

Research output: Contribution to journal › Journal article › Research › peer-review

The genetic and environmental influences on childhood obesity: a systematic review of twin and adoption studies

Silventoinen, K., Rokholm, B., Kaprio, J. & Sørensen, Thorkild I.A., 1 Jan 2010, In: International Journal of Obesity. 34, 1, p. 29-40 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Dietary fiber and subsequent changes in body weight and waist circumference in European men and women

Du, H., van der A, D. L., Boshuizen, H. C., Forouhi, N. G., Wareham, N. J., Halkjaer, J., Tjønneland, A., Overvad, K., Jakobsen, M. U., Boeing, H., Buijsse, B., Masala, G., Palli, D., Sørensen, Thorkild I.A., Saris, W. H. M. & Feskens, E. J. M., 1 Feb 2010, In: American Journal of Clinical Nutrition. 91, 2, p. 329-36 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge

Saxena, R., Hivert, M-F., Langenberg, C., Tanaka, T., Pankow, J. S., Vollenweider, P., Lyssenko, V., Bouatia-Naji, N., Dupuis, J., Jackson, A. U., Kao, W. H. L., Li, M., Glazer, N. L., Manning, A. K., Luan, J., Stringham, H. M., Prokopenko, I., Johnson, T., Grarup, N., Boesgaard, T. W. & 31 others, Lecoeur, C., Shrader, P., O'Connell, J., Ingelsson, E., Couper, D. J., Rice, K., Song, K., Andreasen, C. H., Dina, C., Köttgen, A., Le Bacquer, O., Pattou, F., Taneera, J., Steinthorsdottir, V., Rybin, D., Ardlie, K., Sampson, M., Qi, L., van Hoek, M., Weedon, M. N., Aulchenko, Y. S., Voight, B. F., Grallert, H., Balkau, B., Bergman, R. N., Borch-Johnsen, K., Jørgensen, T., Sparsø, T., Hansen, Torben, Pedersen, Oluf Borbye & GIANT Consortium, G. C., 1 Feb 2010, In: Nature Genetics. 42, 2, p. 142-8 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

Dupuis, J., Langenberg, C., Prokopenko, I., Saxena, R., Soranzo, N., Jackson, A. U., Wheeler, E., Glazer, N. L., Bouatia-Naji, N., Gloyn, A. L., Lindgren, C. M., Mägi, R., Morris, A. P., Randall, J., Johnson, T., Elliott, P., Rybin, D., Thorleifsson, G., Steinthorsdottir, V., Henneman, P. & 31 others, Grallert, H., Dehghan, A., Hottenga, J. J., Franklin, C. S., Navarro, P., Song, K., Goel, A., Perry, J. R. B., Egan, J. M., Lajunen, T., Grarup, Niels, Sparsø, T., Doney, A., Voight, B. F., Stringham, H. M., Li, M., Kanoni, S., Shrader, P., Cavalcanti-Proença, C., Kumari, M., Qi, L., Timpson, N. J., Gieger, C., Zabena, C., Rocheleau, G., Ingelsson, E., An, P., Jørgensen, T., Hansen, Torben, Pedersen, Oluf Borbye & DIAGRAM Consortium, D. C., 1 Feb 2010, In: Nature Genetics. 42, 2, p. 105-16 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Obesity as a clinical and public health problem: is there a need for a new definition based on lipotoxicity effects?

Sørensen, Thorkild I.A., Virtue, S. & Vidal-Puig, A., 1 Mar 2010, In: B B A - Molecular and Cell Biology of Lipids. 1801, 3, p. 400-4 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Interdependence of AMPK and SIRT1 for metabolic adaptation to fasting and exercise in skeletal muscle

Cantó, C., Jiang, L. Q., Deshmukh, Atul Shahaji, Mataki, C., Coste, A., Lagouge, M., Zierath, Juleen R & Auwerx, J., 3 Mar 2010, In: Cell Metabolism. 11, 3, p. 213-9 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Down-regulation of HSP27 sensitizes TRAIL-resistant tumor cell to TRAIL-induced apoptosis

Zhuang, H., Jiang, W., Cheng, W., Qian, K., Dong, W., Cao, L., Huang, Q., Li, S., Dou, F., Chiu, J., Fang, X., Lu, M. & Hua, Z., Apr 2010, In: Lung Cancer. 68, 1, p. 27-38 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Twin study of heritability of eating bread in Danish and Finnish men and women

Hasselbalch, A. L., Silventoinen, K., Keskitalo, K., Pietiläinen, K. H., Rissanen, A., Heitmann, B. L., Kyvik, K. O., Sørensen, Thorkild I.A. & Kaprio, J., 1 Apr 2010, In: Twin Research and Human Genetics. 13, 2, p. 163-7 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Associations between dietary intake and body fat independent of genetic and familial environmental background

Hasselbalch, A. L., Heitmann, B. L., Kyvik, K. O. & Sørensen, Thorkild I.A., 1 May 2010, In: International Journal of Obesity. 34, 5, p. 892-8 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Genetic and environmental influences on risk of death due to infections assessed in Danish twins, 1943-2001

Obel, Niels, Christensen, K., Petersen, I., Sørensen, Thorkild I.A. & Skytthe, A., 1 May 2010, In: American Journal of Epidemiology. 171, 9, p. 1007-13 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Nitric oxide increases cyclic GMP levels, AMP-activated protein kinase (AMPK)alpha1-specific activity and glucose transport in human skeletal muscle

Deshmukh, Atul Shahaji, Long, Y. C., de Castro Barbosa, T., Karlsson, H. K. R., Glund, S., Zavadoski, W. J., Gibbs, E. M., Koistinen, H. A., Wallberg-Henriksson, H. & Zierath, Juleen R, Jun 2010, In: Diabetologia. 53, 6, p. 1142-50 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Impact of psychological stress on the associations between apolipoprotein E variants and metabolic traits: findings in an American sample of caregivers and controls

Kring, S. I., Brummett, B. H., Barefoot, J., Garrett, M. E., Ashley-Koch, A. E., Boyle, S. H., Siegler, I. C., Sørensen, Thorkild I.A. & Williams, R. B., 1 Jun 2010, In: Psychosomatic Medicine. 72, 5, p. 427-33 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

A novel intronic peroxisome proliferator-activated receptor gamma enhancer in the uncoupling protein (UCP) 3 gene as a regulator of both UCP2 and -3 expression in adipocytes

Bugge, A. S., Siersbaek, M., Madsen, M. S., Göndör, A., Rougier, C. & Mandrup, S., 4 Jun 2010, In: The Journal of Biological Chemistry. 285, 23, p. 17310-7 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Studies of association between LPIN1 variants and common metabolic phenotypes among 17,538 Danes

Burgdorf, K. S., Sandholt, C. H., Sparsø, T., Andersen, G., Witte, D. R., Jørgensen, T., Sandbaek, A., Lauritzen, T., Sørensen, Thorkild I.A., Madsbad, Sten, Hansen, Torben & Pedersen, Oluf Borbye, 1 Jul 2010, In: European Journal of Endocrinology. 163, 1, p. 81-7 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

Voight, B. F., Scott, L. J., Steinthorsdottir, V., Morris, A. P., Dina, C., Welch, R. P., Zeggini, E., Huth, C., Aulchenko, Y. S., Thorleifsson, G., McCulloch, L. J., Ferreira, T., Grallert, H., Amin, N., Wu, G., Willer, C. J., Raychaudhuri, S., McCarroll, S. A., Langenberg, C., Hofmann, O. M. & 31 others, Dupuis, J., Qi, L., Segrè, A. V., van Hoek, M., Navarro, P., Ardlie, K., Balkau, B., Benediktsson, R., Bennett, A. J., Blagieva, R., Boerwinkle, E., Bonnycastle, L. L., Bengtsson Boström, K., Bravenboer, B., Bumpstead, S., Burtt, N. P., Charpentier, G., Chines, P. S., Cornelis, M., Couper, D. J., Crawford, G., Doney, A. S. F., Elliott, K. S., Elliott, A. L., Erdos, M. R., Grarup, Niels, Jørgensen, T., Sparsø, T., Hansen, Torben, Pedersen, Oluf Borbye & MAGIC investigators, M. I., 1 Jul 2010, In: Nature Genetics. 42, 7, p. 579-89 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

LMNA rs4641 and the muscle lamin A and C isoforms in twins--metabolic implications and transcriptional regulation

Wegner, L., Anthonsen, S., Bork-Jensen, J., Dalgaard, L., Hansen, Torben, Pedersen, Oluf Borbye, Poulsen, P. & Vaag, Allan, Aug 2010, In: The Journal of clinical endocrinology and metabolism. 95, 8, p. 3884-92 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Nutrient-dependent regulation of PGC-1α's acetylation state and metabolic function through the enzymatic activities of Sirt1/GCN5

Dominy, J. E., Lee, Y., Gerhart-Hines, Zach & Puigserver, P., Aug 2010, In: Biochimica et Biophysica Acta - Proteins and Proteomics. 1804, 8, p. 1676-1683 8 p.

Research output: Contribution to journal › Review › Research › peer-review

The intracellular to extracellular proton gradient following maximal whole body exercise and its implication for anaerobic energy production

Voiantis, S., Secher, Niels H. & Quistorff, B., Aug 2010, In: European Journal of Applied Physiology. 109, 6, p. 1171-1177 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

A maternal low protein diet has pronounced effects on mitochondrial gene expression in offspring liver and skeletal muscle; protective effect of taurine

Mortensen, Ole Hartvig, Olsen, H. L., Frandsen, L., Nielsen, Peter E., Nielsen, Finn Cilius, Grunnet, N. & Quistorff, B., 1 Aug 2010, In: Journal of Biomedical Science. 24, 17, p. 1-11

Research output: Contribution to journal › Journal article › Research › peer-review

Effects of erythropoietin administration on cerebral metabolism and exercise capacity in men

Rasmussen, P., Foged, E. M., Krogh-Madsen, Rikke, Nielsen, Jannie, Nielsen, Thomas Rune, Olsen, N. V., Petersen, Nicolas Caesar, Sørensen, T. A., Secher, Niels H., Lundby, C., Rasmussen, P., Foged, E. M., Krogh-Madsen, R., Nielsen, J., Nielsen, T. R., Olsen, N. V., Petersen, N. C., Sørensen, Thorkild I.A., Secher, Niels H. & Lundby, C., 1 Aug 2010, In: Journal of Applied Physiology. 109, 2, p. 476-83 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Genome-wide association study identifies a sequence variant within the DAB2IP gene conferring susceptibility to abdominal aortic aneurysm

Gretarsdottir, S., Baas, A. F., Thorleifsson, G., Holm, H., den Heijer, M., de Vries, J-P. P. M., Kranendonk, S. E., Zeebregts, C. J. A. M., van Sterkenburg, S. M., Geelkerken, R. H., van Rij, A. M., Williams, M. J. A., Boll, A. P. M., Kostic, J. P., Jonasdottir, A., Jonasdottir, A., Walters, G. B., Masson, G., Sulem, P., Saemundsdottir, J. & 82 others, Mouy, M., Magnusson, K. P., Tromp, G., Elmore, J. R., Sakalihasan, N., Limet, R., Defraigne, J., Ferrell, R. E., Ronkainen, A., Ruigrok, Y. M., Wijmenga, C., Grobbee, D. E., Shah, S. H., Granger, C. B., Quyyumi, A. A., Vaccarino, V., Patel, R. S., Zafari, A. M., Levey, A. I., Austin, H., Girelli, D., Pignatti, P. F., Olivieri, O., Martinelli, N., Malerba, G., Trabetti, E., Becker, L. C., Becker, D. M., Reilly, M. P., Rader, D. J., Mueller, T., Dieplinger, B., Haltmayer, M., Urbonavicius, S., Lindblad, B., Gottsäter, A., Gaetani, E., Pola, R., Wells, P., Rodger, M., Forgie, M., Langlois, N., Corral, J., Vasquez, V., Fontcuberta, J., España, F., Grarup, Niels, Jørgensen, T., Witte, D. R., Hansen, Torben, Pedersen, Oluf Borbye, Aben, K. K., de Graaf, J., Holewijn, S., Folkersen, L., Franco-Cereceda, A., Eriksson, P., Collier, D. A., Stefansson, H., Steinthorsdottir, V., Rafnar, T., Valdimarsson, E. M., Magnadottir, H. B., Sveinbjornsdottir, S., Olafsson, I., Magnusson, M. K., Palmason, R., Haraldsdottir, V., Andersen, K., Onundarson, P. T., Thorgeirsson, G., Kiemeney, L. A., Powell, J. T., Carey, D. J., Kuivaniemi, H., Lindholt, J. S., Jones, G. T., Kong, A., Blankensteijn, J. D., Matthiasson, S. E., Thorsteinsdottir, U. & Stefansson, K., 1 Aug 2010, In: Nature Genetics. 42, 8, p. 692-7 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Influence of lifestyle aspects on the association of body size and shape with all-cause mortality in middle-aged men and women

Bigaard, J., Christensen, J., Tjønneland, A., Thomsen, B. L. R., Overvad, K. & Sørensen, Thorkild I.A., 1 Aug 2010, In: Obesity Facts. 3, 4, p. 252-60 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Variants at DGKB/TMEM195, ADRA2A, GLIS3 and C2CD4B loci are associated with reduced glucose-stimulated beta cell function in middle-aged Danish people

Boesgaard, T. W., Grarup, Niels, Jørgensen, T., Borch-Johnsen, K., Hansen, Torben, Pedersen, Oluf Borbye & Meta-Analysis of Glucose and Insulin-Related Trait Consortium (MAGIC), M. O. G. A. I. T. C. (., 1 Aug 2010, In: Diabetologia. 53, 8, p. 1647-55 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

High body mass index in adolescent girls precedes psoriasis hospitalization

Bryld, L. E., Sørensen, Thorkild I.A., Andersen, K. K., Jemec, G. & Baker, J. L., 1 Sep 2010, In: Acta Dermato Venereologica. 90, 5, p. 488-93 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Latent autoimmune diabetes in adults differs genetically from classical type 1 diabetes diagnosed after the age of 35 years

Lepola, Mette Andersen, Lundgren, V., Turunen, J. A., Forsblom, C., Isomaa, B., Groop, P. H., Groop, L. & Tuomi, T., 1 Sep 2010, In: Diabetes Care. 33, 9, p. 2062-2064 3 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Type 2 diabetes risk alleles near ADCY5, CDKAL1 and HHEX-IDE are associated with reduced birthweight

Andersson, E. A., Pilgaard, K., Pisinger, C., Harder, M. N., Grarup, Niels, Faerch, K., Poulsen, P., Witte, D. R., Jørgensen, T., Vaag, Allan, Hansen, Torben & Pedersen, Oluf Borbye, 1 Sep 2010, In: Diabetologia. 53, 9, p. 1908-16 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

SmashCell: A software framework for the analysis of single-cell amplified genome sequences.

Harrington, E. D., Arumugam, Mani, Raes, J., Bork, P. & Relman, D. A., Oct 2010, In: Bioinformatics. 26, 23, p. 2979-2980 2 p.

Research output: Contribution to journal › Journal article › Research › peer-review

SmashCommunity: A metagenomic annotation and analysis tool.

Arumugam, Mani, Harrington, E. D., Foerstner, K. U., Raes, J. & Bork, P., Oct 2010, In: Bioinformatics. 26, 23, p. 2977-2978 2 p.

Research output: Contribution to journal › Journal article › Research › peer-review

A genome-wide association study in the Japanese population identifies susceptibility loci for type 2 diabetes at UBE2E2 and C2CD4A-C2CD4B

Yamauchi, T., Hara, K., Maeda, S., Yasuda, K., Takahashi, A., Horikoshi, M., Nakamura, M., Fujita, H., Grarup, N., Cauchi, S., Ng, D. P. K., Ma, R. C. W., Tsunoda, T., Kubo, M., Watada, H., Maegawa, H., Okada-Iwabu, M., Iwabu, M., Shojima, N., Shin, H. D. & 26 others, Andersen, G., Witte, D. R., Jørgensen, T., Lauritzen, T., Sandbæk, A., Hansen, T., Ohshige, T., Omori, S., Saito, I., Kaku, K., Hirose, H., So, W., Beury, D., Chan, J. C. N., Park, K. S., Tai, E. S., Ito, C., Tanaka, Y., Kashiwagi, A., Kawamori, R., Kasuga, M., Froguel, P., Pedersen, Oluf Borbye, Kamatani, N., Nakamura, Y. & Kadowaki, T., 1 Oct 2010, In: Nature Genetics. 42, 10, p. 864-8 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Expression of mRNA for proglucagon and glucagon-like peptide-2 (GLP-2) receptor in the ruminant gastrointestinal tract and the influence of energy intake

Taylor-Edwards, C. C., Burrin, D. G., Matthews, J. C., McLeod, K. R., Holst, Jens Juul & Harmon, D. L., 1 Oct 2010, In: Domestic Animal Endocrinology. 39, 3, p. 181-93 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Revising consensus in portal hypertension: report of the Baveno V consensus workshop on methodology of diagnosis and therapy in portal hypertension

de Franchis, R., Baveno V Faculty, B. V. F. & Sørensen, Thorkild I.A., 1 Oct 2010, In: Journal of Hepatology. 53, 4, p. 762-8 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The intestinotrophic peptide, GLP-2, counteracts the gastrointestinal atrophy in mice induced by the epidermal growth factor receptor inhibitor, erlotinib, and cisplatin

Rasmussen, A. R., Viby, N., Hare, K. J., Hartmann, Bolette, Thim, L., Holst, Jens Juul & Poulsen, Steen Seier, 1 Oct 2010, In: Digestive Diseases and Sciences. 55, 10, p. 2785-96 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Kardiale virkninger af glukagonlignende peptid 1

Holst, Jens Juul, 11 Oct 2010, In: Ugeskrift for Laeger. 172, 41, p. 2821 1 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Chronic high-fat diet in fathers programs ß-cell dysfunction in female rat offspring

Ng, S., Lin, R. C. Y., Laybutt, D. R., Barrès, Romain, Owens, J. A. & Morris, M. J., 21 Oct 2010, In: Nature. 467, 7318, p. 963-6 4 p.

Research output: Contribution to journal › Journal article › Research › peer-review

A cereal-based evening meal rich in indigestible carbohydrates increases plasma butyrate the next morning

Nilsson, A. C., Östman, E. M., Knudsen, K. E. B., Holst, Jens Juul & Björck, I. M. E., 1 Nov 2010, In: Journal of Nutrition. 140, 11, p. 1932-6 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

Speliotes, E. K., Willer, C. J., Berndt, S. I., Monda, K. L., Thorleifsson, G., Jackson, A. U., Allen, H. L., Lindgren, C. M., Luan, J., Mägi, R., Randall, J. C., Vedantam, S., Winkler, T. W., Lu, Q., Workalemahu, T., Heid, I. M., Steinthorsdottir, V., Stringham, H. M., Weedon, M. N., Wheeler, E. & 31 others, Wood, A. R., Ferreira, T., Weyant, R. J., Segrè, A. V., Estrada, K., Liang, L., Nemesh, J., Park, J., Gustafsson, S., Kilpeläinen, Tuomas O., Yang, J., Bouatia-Naji, N., Esko, T., Feitosa, M. F., Kutalik, Z., Mangino, M., Raychaudhuri, S., Scherag, A., Smith, A. V., Welch, R., Zhao, J. H., Aben, K. K., Absher, D. M., Amin, N., Dixon, A. L., Gjesing, A. P., Jørgensen, T., Witte, D. R., Hansen, Torben, Pedersen, Oluf Borbye & MAGIC, M., 1 Nov 2010, In: Nature Genetics. 42, 11, p. 937-48 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Differential incretin effects of GIP and GLP-1 on gastric emptying, appetite, and insulin-glucose homeostasis

Edholm, T., Degerblad, M., Grybäck, P., Hilsted, Linda, Holst, Jens Juul, Jacobsson, H., Efendic, S., Schmidt, P. T. & Hellström, P. M., 1 Nov 2010, In: Neurogastroenterology and Motility Online. 22, 11, p. 1191-200, e315 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Insulin resistance induced by physical inactivity is associated with multiple transcriptional changes in skeletal muscle in young men

Alibegovic, A. C., Sonne, M. P., Højbjerre, L., Bork-Jensen, J., Jacobsen, S., Nilsson, E., Faerch, K., Hiscock, N., Mortensen, B., Friedrichsen, M., Stallknecht, Bente Merete, Dela, Flemming & Vaag, Allan, 1 Nov 2010, In: American Journal of Physiology: Endocrinology and Metabolism. 299, 5, p. E752-63 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

Heid, I. M., Jackson, A. U., Randall, J. C., Winkler, T. W., Qi, L., Steinthorsdottir, V., Thorleifsson, G., Zillikens, M. C., Speliotes, E. K., Mägi, R., Workalemahu, T., White, C. C., Bouatia-Naji, N., Harris, T. B., Berndt, S. I., Ingelsson, E., Willer, C. J., Weedon, M. N., Luan, J., Vedantam, S. & 31 others, Esko, T., Kilpeläinen, Tuomas O., Kutalik, Z., Li, S., Monda, K. L., Dixon, A. L., Holmes, C. C., Kaplan, L. M., Liang, L., Min, J. L., Moffatt, M. F., Molony, C., Nicholson, G., Schadt, E. E., Zondervan, K. T., Feitosa, M. F., Ferreira, T., Allen, H. L., Weyant, R. J., Wheeler, E., Wood, A. R., Estrada, K., Goddard, M. E., Lettre, G., Mangino, M., Gjesing, A. P., Witte, D. R., Hansen, Torben, Jørgensen, T., Pedersen, Oluf Borbye & MAGIC, M., 1 Nov 2010, In: Nature Genetics. 42, 11, p. 949-60 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Overweight and obesity trends in Copenhagen schoolchildren from 2002 to 2007

Pearson, S., Hansen, B., Sørensen, Thorkild I.A. & Baker, J. L., 1 Nov 2010, In: Acta Paediatrica. 99, 11, p. 1675-8 4 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Neuronal calcium sensor synaptotagmin-9 is not involved in the regulation of glucose homeostasis or insulin secretion

Gustavsson, N., Wang, X., Wang, Y., Seah, T., Xu, J., Radda, G. K., Südhof, T. C. & Han, W., 9 Nov 2010, In: PLOS ONE. 5, 11, p. e15414

Research output: Contribution to journal › Journal article › Research › peer-review

Genetics of type 2 diabetes.

Ahlqvist, E., Ahluwalia, Tarun Veer Singh & Groop, L., 30 Nov 2010, In: Clinical Chemistry.

Research output: Contribution to journal › Journal article › Research › peer-review

Dipeptidyl peptidase-4 inhibitors administered in combination with metformin result in an additive increase in the plasma concentration of active GLP-1

Migoya, E. M., Bergeron, R., Miller, J. L., Snyder, R. N. K., Tanen, M., Hilliard, D., Weiss, B., Larson, P., Gutierrez, M., Jiang, G., Liu, F., Pryor, K. A., Yao, J., Zhu, L., Holst, J. J., Deacon, C., Herman, G., Thornberry, N., Amatruda, J., Williams-Herman, D. & 2 others, Wagner, J. A. & SinhaRoy, R., 1 Dec 2010, In: Clinical Pharmacology and Therapeutics. 88, 6, p. 801-8 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Glucokinase diabetes in 103 families from a country-based study in the Czech Republic: geographically restricted distribution of two prevalent GCK mutations

Pruhova, S., Dusatkova, P., Sumnik, Z., Kolouskova, S., Pedersen, Oluf Borbye, Hansen, Torben, Cinek, O. & Lebl, J., 1 Dec 2010, In: Pediatric Diabetes Online. 11, 8, p. 529-35 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Low birthweight and premature birth are both associated with type 2 diabetes in a random sample of middle-aged Danes

Pilgaard, K., Færch, K., Carstensen, B., Poulsen, P., Pisinger, C., Pedersen, Oluf Borbye, Witte, D. R., Hansen, Torben, Jørgensen, T. & Vaag, Allan, 1 Dec 2010, In: Diabetologia. 53, 12, p. 2526-30 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Physiologic characterization of type 2 diabetes-related loci

Grarup, Niels, Sparsø, T. & Hansen, Torben, 1 Dec 2010, In: Current Diabetes Reports. 10, 6, p. 485-97 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Prenatal exposures to perfluorinated chemicals and anthropometric measures in infancy

Andersen, C. S., Fei, C., Gamborg, Michael Orland, Nohr, E. A., Sørensen, Thorkild I.A. & Olsen, J., 1 Dec 2010, In: American Journal of Epidemiology. 172, 11, p. 1230-7 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Reduced gluconeogenesis and lactate clearance in Huntington's disease

Josefsen, K., Nielsen, S. M. B., Campos, A., Seifert, T., Hasholt, Lis Frydenreich, Nielsen, Jørgen Erik, Nørremølle, Anne, Skotte, Niels Henning, Secher, Niels H. & Quistorff, B., 1 Dec 2010, In: Neurobiology of Disease. 40, 3, p. 656-62 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Stata tip 92: Manual implementation of permutations and bootstraps

Ängquist, Lars, 1 Dec 2010, In: Stata Journal. 10, 4, p. 686-688 3 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Sustained glucagon-like peptide-2 infusion is required for intestinal adaptation, and cessation reverses increased cellularity in rats with intestinal failure

Koopmann, M. C., Chen, X., Holst, Jens Juul & Ney, D. M., 1 Dec 2010, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 299, 6, p. G1222-30 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The levelling off of the obesity epidemic since the year 1999--a review of evidence and perspectives

Rokholm, B., Baker, J. L. & Sørensen, Thorkild I.A., 1 Dec 2010, In: Obesity Reviews. 11, 12, p. 835-46 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

2-Oleoyl glycerol is a GPR119 agonist and signals GLP-1 release in humans

Hansen, K. B., Rosenkilde, Mette, Knop, Filip Krag, Wellner, N., Diep, T. A., Rehfeld, Jens Frederik, Andersen, U. B., Holst, Jens Juul & Hansen, Harald S., 2011, In: Journal of Clinical Endocrinology and Metabolism. 96, 9, p. E1409-17

Research output: Contribution to journal › Journal article › Research › peer-review

A low glycemic index diet does not affect postprandial energy metabolism but decreases postprandial insulinemia and increases fullness ratings in healthy women

Krog-Mikkelsen, I., Sloth, B., Dimitrov, D., Tetens, Inge , Björck, I., Flint, A., Holst, Jens Juul, Astrup, A., Elmstähl, H. & Raben, Anne, 2011, In: Journal of Nutrition. 141, 9, p. 1679-1684 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Adipose tissue fatty acid patterns and changes in anthropometry: a cohort study

Dahm, C. C., Gorst-Rasmussen, A., Jakobsen, M. U., Schmidt, E. B., Tjønneland, A., Sørensen, Thorkild I.A. & Overvad, K., 2011, In: P L o S One. 6, 7, p. e22587

Research output: Contribution to journal › Journal article › Research › peer-review

Allelic variants of melanocortin 3 receptor gene (MC3R) and weight loss in obesity: a randomised trial of hypo-energetic high- versus low-fat diets

L. Santos, J., De la Cruz, R., Holst, C., Grau, K., Naranjo, C., Maiz, A., Astrup, A., Saris, W. H. M., MacDonald, I., Oppert, J., Hansen, T., Pedersen, Oluf Borbye, Sørensen, Thorkild I.A., Martinez, J. A. & NUGENOB Consortium, 2011, In: P L o S One. 6, 6, p. e199934 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Allosteric and orthosteric sites in CC chemokine receptor (CCR5), a chimeric receptor approach

Thiele, S., Steen, A., Jensen, P. C., Mokrosinski, J., Frimurer, Thomas Michael & Rosenkilde, Mette, 2011, In: Journal of Biological Chemistry. 286, 43, p. 37543-54 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

An Aboriginal Australian genome reveals separate human dispersals into Asia

Rasmussen, M., Guo, X., Wang, Y., Lohmueller, K. E., Rasmussen, S., Albrechtsen, A., Skotte, L., Lindgreen, S., Metspalu, M., Jombart, T., Kivisild, T., Zhai, W., Eriksson, A., Manica, A., Orlando, L., De La Vega, F. M., Tridico, S., Metspalu, E., Nielsen, K., Avila Arcos, M. D. C. & 38 others, Moreno Mayar, J. Víctor, Muller, C., Dortch, J., Gilbert, M Thomas P, Lund, O., Wesolowska, A., Karmin, M., Weinert, L. A., Wang, B., Li, J., Tai, S., Xiao, F., Hanihara, T., van Driem, G., Jha, A. R., Ricaut, F., de Knijff, P., Migliano, A. B., Gallego Romero, I., Kristiansen, Karsten, Lambert, D. M., Brunak, Søren, Forster, P., Brinkmann, B., Nehlich, O., Bunce, M., Richards, M., Gupta, R., Bustamante, C. D., Krogh, Anders, Foley, R. A., Lahr, M. M., Balloux, F., Sicheritz-Pontén, T., Villems, R., Nielsen, Rasmus, Wang, J. & Willerslev, Eske, 2011, In: Science. 334, 6052, p. 94-98 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Androgen receptor and nutrient signaling pathways coordinate the demand for increased amino acid transport during prostate cancer progression

Wang, Q., Bailey, C. G., Ng, C., Tiffen, J., Thoeng, A., Minhas, V., Lehman, M. L., Hendy, S. C., Buchanan, G., Nelson, C. C., Rasko, J. E. J., Holst, J. & Holst, Jens Juul, 2011, In: Cancer Research. 71, 24, p. 7525-7536 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Association between CST3 rs2424577 polymorphism and corpulence related phenotypes during lifetime in populations of European ancestry

Hooton, H., Dubern, B., Henegar, C., Paternoster, L., Nohr, E. A., Alili, R., Rousseau, F., Pelloux, V., Galan, P., Hercberg, S., Arner, P., Sørensen, Thorkild I.A. & Clément, K., 2011, In: Obesity Facts. 4, 2, p. 131-44 14 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Associations between APOE variants and metabolic traits and the impact of psychological stress

Kring, S. I. I., Barefoot, J., Brummett, B. H., Boyle, S. H., Siegler, I. C., Toubro, S., Hansen, T., Astrup, A., Pedersen, Oluf Borbye, Williams, R. B. & Sørensen, Thorkild I.A., 2011, In: PLoS ONE. 6, 1, 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Back to basics

Söderqvist, Thomas & Arnold, Ken, 2011, In: Museums Journal. 111, 2, p. 22-27 6 p.

Research output: Contribution to journal › Journal article › Commissioned

C-peptide increases Na,K-ATPase expression via PKC- and MAP kinase-dependent activation of transcription factor ZEB in human renal tubular cells

Galuska, D., Pirkmajer, S., Barrès, Romain, Ekberg, K., Wahren, J. & Chibalin, A. V., 2011, In: P L o S One. 6, 12, p. e28294

Research output: Contribution to journal › Journal article › Research › peer-review