- 2010
- Published
Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge
Saxena, R., Hivert, M-F., Langenberg, C., Tanaka, T., Pankow, J. S., Vollenweider, P., Lyssenko, V., Bouatia-Naji, N., Dupuis, J., Jackson, A. U., Kao, W. H. L., Li, M., Glazer, N. L., Manning, A. K., Luan, J., Stringham, H. M., Prokopenko, I., Johnson, T., Grarup, N., Boesgaard, T. W. & 31 others, , 1 Feb 2010, In: Nature Genetics. 42, 2, p. 142-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
Dupuis, J., Langenberg, C., Prokopenko, I., Saxena, R., Soranzo, N., Jackson, A. U., Wheeler, E., Glazer, N. L., Bouatia-Naji, N., Gloyn, A. L., Lindgren, C. M., Mägi, R., Morris, A. P., Randall, J., Johnson, T., Elliott, P., Rybin, D., Thorleifsson, G., Steinthorsdottir, V., Henneman, P. & 31 others, , 1 Feb 2010, In: Nature Genetics. 42, 2, p. 105-16 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Obesity as a clinical and public health problem: is there a need for a new definition based on lipotoxicity effects?
Sørensen, Thorkild I.A., Virtue, S. & Vidal-Puig, A., 1 Mar 2010, In: B B A - Molecular and Cell Biology of Lipids. 1801, 3, p. 400-4 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Interdependence of AMPK and SIRT1 for metabolic adaptation to fasting and exercise in skeletal muscle
Cantó, C., Jiang, L. Q., Deshmukh, Atul Shahaji, Mataki, C., Coste, A., Lagouge, M., Zierath, Juleen R & Auwerx, J., 3 Mar 2010, In: Cell Metabolism. 11, 3, p. 213-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Down-regulation of HSP27 sensitizes TRAIL-resistant tumor cell to TRAIL-induced apoptosis
Zhuang, H., Jiang, W., Cheng, W., Qian, K., Dong, W., Cao, L., Huang, Q., Li, S., Dou, F., Chiu, J., Fang, X., Lu, M. & Hua, Z., Apr 2010, In: Lung Cancer. 68, 1, p. 27-38 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Twin study of heritability of eating bread in Danish and Finnish men and women
Hasselbalch, A. L., Silventoinen, K., Keskitalo, K., Pietiläinen, K. H., Rissanen, A., Heitmann, B. L., Kyvik, K. O., Sørensen, Thorkild I.A. & Kaprio, J., 1 Apr 2010, In: Twin Research and Human Genetics. 13, 2, p. 163-7 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Associations between dietary intake and body fat independent of genetic and familial environmental background
Hasselbalch, A. L., Heitmann, B. L., Kyvik, K. O. & Sørensen, Thorkild I.A., 1 May 2010, In: International Journal of Obesity. 34, 5, p. 892-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic and environmental influences on risk of death due to infections assessed in Danish twins, 1943-2001
Obel, Niels, Christensen, K., Petersen, I., Sørensen, Thorkild I.A. & Skytthe, A., 1 May 2010, In: American Journal of Epidemiology. 171, 9, p. 1007-13 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nitric oxide increases cyclic GMP levels, AMP-activated protein kinase (AMPK)alpha1-specific activity and glucose transport in human skeletal muscle
Deshmukh, Atul Shahaji, Long, Y. C., de Castro Barbosa, T., Karlsson, H. K. R., Glund, S., Zavadoski, W. J., Gibbs, E. M., Koistinen, H. A., Wallberg-Henriksson, H. & Zierath, Juleen R, Jun 2010, In: Diabetologia. 53, 6, p. 1142-50 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of psychological stress on the associations between apolipoprotein E variants and metabolic traits: findings in an American sample of caregivers and controls
Kring, S. I., Brummett, B. H., Barefoot, J., Garrett, M. E., Ashley-Koch, A. E., Boyle, S. H., Siegler, I. C., Sørensen, Thorkild I.A. & Williams, R. B., 1 Jun 2010, In: Psychosomatic Medicine. 72, 5, p. 427-33 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A novel intronic peroxisome proliferator-activated receptor gamma enhancer in the uncoupling protein (UCP) 3 gene as a regulator of both UCP2 and -3 expression in adipocytes
Bugge, A. S., Siersbaek, M., Madsen, M. S., Göndör, A., Rougier, C. & Mandrup, S., 4 Jun 2010, In: The Journal of Biological Chemistry. 285, 23, p. 17310-7 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Studies of association between LPIN1 variants and common metabolic phenotypes among 17,538 Danes
Burgdorf, K. S., Sandholt, C. H., Sparsø, T., Andersen, G., Witte, D. R., Jørgensen, T., Sandbaek, A., Lauritzen, T., Sørensen, Thorkild I.A., Madsbad, Sten, Hansen, Torben & Pedersen, Oluf Borbye, 1 Jul 2010, In: European Journal of Endocrinology. 163, 1, p. 81-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis
Voight, B. F., Scott, L. J., Steinthorsdottir, V., Morris, A. P., Dina, C., Welch, R. P., Zeggini, E., Huth, C., Aulchenko, Y. S., Thorleifsson, G., McCulloch, L. J., Ferreira, T., Grallert, H., Amin, N., Wu, G., Willer, C. J., Raychaudhuri, S., McCarroll, S. A., Langenberg, C., Hofmann, O. M. & 31 others, , 1 Jul 2010, In: Nature Genetics. 42, 7, p. 579-89 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
LMNA rs4641 and the muscle lamin A and C isoforms in twins--metabolic implications and transcriptional regulation
Wegner, L., Anthonsen, S., Bork-Jensen, J., Dalgaard, L., Hansen, Torben, Pedersen, Oluf Borbye, Poulsen, P. & Vaag, Allan, Aug 2010, In: The Journal of clinical endocrinology and metabolism. 95, 8, p. 3884-92 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nutrient-dependent regulation of PGC-1α's acetylation state and metabolic function through the enzymatic activities of Sirt1/GCN5
Dominy, J. E., Lee, Y., Gerhart-Hines, Zach & Puigserver, P., Aug 2010, In: Biochimica et Biophysica Acta - Proteins and Proteomics. 1804, 8, p. 1676-1683 8 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
The intracellular to extracellular proton gradient following maximal whole body exercise and its implication for anaerobic energy production
Voiantis, S., Secher, Niels H. & Quistorff, B., Aug 2010, In: European Journal of Applied Physiology. 109, 6, p. 1171-1177 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A maternal low protein diet has pronounced effects on mitochondrial gene expression in offspring liver and skeletal muscle; protective effect of taurine
Mortensen, Ole Hartvig, Olsen, H. L., Frandsen, L., Nielsen, Peter E., Nielsen, Finn Cilius, Grunnet, N. & Quistorff, B., 1 Aug 2010, In: Journal of Biomedical Science. 24, 17, p. 1-11Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of erythropoietin administration on cerebral metabolism and exercise capacity in men
Rasmussen, P., Foged, E. M., Krogh-Madsen, Rikke, Nielsen, Jannie, Nielsen, Thomas Rune, Olsen, N. V., Petersen, Nicolas Caesar, Sørensen, T. A., Secher, Niels H., Lundby, C., Rasmussen, P., Foged, E. M., Krogh-Madsen, R., Nielsen, J., Nielsen, T. R., Olsen, N. V., Petersen, N. C., Sørensen, Thorkild I.A., Secher, Niels H. & Lundby, C., 1 Aug 2010, In: Journal of Applied Physiology. 109, 2, p. 476-83 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide association study identifies a sequence variant within the DAB2IP gene conferring susceptibility to abdominal aortic aneurysm
Gretarsdottir, S., Baas, A. F., Thorleifsson, G., Holm, H., den Heijer, M., de Vries, J-P. P. M., Kranendonk, S. E., Zeebregts, C. J. A. M., van Sterkenburg, S. M., Geelkerken, R. H., van Rij, A. M., Williams, M. J. A., Boll, A. P. M., Kostic, J. P., Jonasdottir, A., Jonasdottir, A., Walters, G. B., Masson, G., Sulem, P., Saemundsdottir, J. & 82 others, , 1 Aug 2010, In: Nature Genetics. 42, 8, p. 692-7 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of lifestyle aspects on the association of body size and shape with all-cause mortality in middle-aged men and women
Bigaard, J., Christensen, J., Tjønneland, A., Thomsen, B. L. R., Overvad, K. & Sørensen, Thorkild I.A., 1 Aug 2010, In: Obesity Facts. 3, 4, p. 252-60 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Variants at DGKB/TMEM195, ADRA2A, GLIS3 and C2CD4B loci are associated with reduced glucose-stimulated beta cell function in middle-aged Danish people
Boesgaard, T. W., Grarup, Niels, Jørgensen, T., Borch-Johnsen, K., Hansen, Torben, Pedersen, Oluf Borbye & Meta-Analysis of Glucose and Insulin-Related Trait Consortium (MAGIC), M. O. G. A. I. T. C. (., 1 Aug 2010, In: Diabetologia. 53, 8, p. 1647-55 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High body mass index in adolescent girls precedes psoriasis hospitalization
Bryld, L. E., Sørensen, Thorkild I.A., Andersen, K. K., Jemec, G. & Baker, J. L., 1 Sep 2010, In: Acta Dermato Venereologica. 90, 5, p. 488-93 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Latent autoimmune diabetes in adults differs genetically from classical type 1 diabetes diagnosed after the age of 35 years
Lepola, Mette Andersen, Lundgren, V., Turunen, J. A., Forsblom, C., Isomaa, B., Groop, P. H., Groop, L. & Tuomi, T., 1 Sep 2010, In: Diabetes Care. 33, 9, p. 2062-2064 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Type 2 diabetes risk alleles near ADCY5, CDKAL1 and HHEX-IDE are associated with reduced birthweight
Andersson, E. A., Pilgaard, K., Pisinger, C., Harder, M. N., Grarup, Niels, Faerch, K., Poulsen, P., Witte, D. R., Jørgensen, T., Vaag, Allan, Hansen, Torben & Pedersen, Oluf Borbye, 1 Sep 2010, In: Diabetologia. 53, 9, p. 1908-16 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
SmashCell: A software framework for the analysis of single-cell amplified genome sequences.
Harrington, E. D., Arumugam, Mani, Raes, J., Bork, P. & Relman, D. A., Oct 2010, In: Bioinformatics. 26, 23, p. 2979-2980 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
SmashCommunity: A metagenomic annotation and analysis tool.
Arumugam, Mani, Harrington, E. D., Foerstner, K. U., Raes, J. & Bork, P., Oct 2010, In: Bioinformatics. 26, 23, p. 2977-2978 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A genome-wide association study in the Japanese population identifies susceptibility loci for type 2 diabetes at UBE2E2 and C2CD4A-C2CD4B
Yamauchi, T., Hara, K., Maeda, S., Yasuda, K., Takahashi, A., Horikoshi, M., Nakamura, M., Fujita, H., Grarup, N., Cauchi, S., Ng, D. P. K., Ma, R. C. W., Tsunoda, T., Kubo, M., Watada, H., Maegawa, H., Okada-Iwabu, M., Iwabu, M., Shojima, N., Shin, H. D. & 26 others, , 1 Oct 2010, In: Nature Genetics. 42, 10, p. 864-8 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Expression of mRNA for proglucagon and glucagon-like peptide-2 (GLP-2) receptor in the ruminant gastrointestinal tract and the influence of energy intake
Taylor-Edwards, C. C., Burrin, D. G., Matthews, J. C., McLeod, K. R., Holst, Jens Juul & Harmon, D. L., 1 Oct 2010, In: Domestic Animal Endocrinology. 39, 3, p. 181-93 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Revising consensus in portal hypertension: report of the Baveno V consensus workshop on methodology of diagnosis and therapy in portal hypertension
de Franchis, R., Baveno V Faculty, B. V. F. & Sørensen, Thorkild I.A., 1 Oct 2010, In: Journal of Hepatology. 53, 4, p. 762-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The intestinotrophic peptide, GLP-2, counteracts the gastrointestinal atrophy in mice induced by the epidermal growth factor receptor inhibitor, erlotinib, and cisplatin
Rasmussen, A. R., Viby, N., Hare, K. J., Hartmann, Bolette, Thim, L., Holst, Jens Juul & Poulsen, Steen Seier, 1 Oct 2010, In: Digestive Diseases and Sciences. 55, 10, p. 2785-96 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Kardiale virkninger af glukagonlignende peptid 1
Holst, Jens Juul, 11 Oct 2010, In: Ugeskrift for Laeger. 172, 41, p. 2821 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Chronic high-fat diet in fathers programs ß-cell dysfunction in female rat offspring
Ng, S., Lin, R. C. Y., Laybutt, D. R., Barrès, Romain, Owens, J. A. & Morris, M. J., 21 Oct 2010, In: Nature. 467, 7318, p. 963-6 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A cereal-based evening meal rich in indigestible carbohydrates increases plasma butyrate the next morning
Nilsson, A. C., Östman, E. M., Knudsen, K. E. B., Holst, Jens Juul & Björck, I. M. E., 1 Nov 2010, In: Journal of Nutrition. 140, 11, p. 1932-6 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index
Speliotes, E. K., Willer, C. J., Berndt, S. I., Monda, K. L., Thorleifsson, G., Jackson, A. U., Allen, H. L., Lindgren, C. M., Luan, J., Mägi, R., Randall, J. C., Vedantam, S., Winkler, T. W., Lu, Q., Workalemahu, T., Heid, I. M., Steinthorsdottir, V., Stringham, H. M., Weedon, M. N., Wheeler, E. & 31 others, , 1 Nov 2010, In: Nature Genetics. 42, 11, p. 937-48 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differential incretin effects of GIP and GLP-1 on gastric emptying, appetite, and insulin-glucose homeostasis
Edholm, T., Degerblad, M., Grybäck, P., Hilsted, Linda, Holst, Jens Juul, Jacobsson, H., Efendic, S., Schmidt, P. T. & Hellström, P. M., 1 Nov 2010, In: Neurogastroenterology and Motility Online. 22, 11, p. 1191-200, e315 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Insulin resistance induced by physical inactivity is associated with multiple transcriptional changes in skeletal muscle in young men
Alibegovic, A. C., Sonne, M. P., Højbjerre, L., Bork-Jensen, J., Jacobsen, S., Nilsson, E., Faerch, K., Hiscock, N., Mortensen, B., Friedrichsen, M., Stallknecht, Bente Merete, Dela, Flemming & Vaag, Allan, 1 Nov 2010, In: American Journal of Physiology: Endocrinology and Metabolism. 299, 5, p. E752-63 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution
Heid, I. M., Jackson, A. U., Randall, J. C., Winkler, T. W., Qi, L., Steinthorsdottir, V., Thorleifsson, G., Zillikens, M. C., Speliotes, E. K., Mägi, R., Workalemahu, T., White, C. C., Bouatia-Naji, N., Harris, T. B., Berndt, S. I., Ingelsson, E., Willer, C. J., Weedon, M. N., Luan, J., Vedantam, S. & 31 others, , 1 Nov 2010, In: Nature Genetics. 42, 11, p. 949-60 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Overweight and obesity trends in Copenhagen schoolchildren from 2002 to 2007
Pearson, S., Hansen, B., Sørensen, Thorkild I.A. & Baker, J. L., 1 Nov 2010, In: Acta Paediatrica. 99, 11, p. 1675-8 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Neuronal calcium sensor synaptotagmin-9 is not involved in the regulation of glucose homeostasis or insulin secretion
Gustavsson, N., Wang, X., Wang, Y., Seah, T., Xu, J., Radda, G. K., Südhof, T. C. & Han, W., 9 Nov 2010, In: PLOS ONE. 5, 11, p. e15414Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetics of type 2 diabetes.
Ahlqvist, E., Ahluwalia, Tarun Veer Singh & Groop, L., 30 Nov 2010, In: Clinical Chemistry.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dipeptidyl peptidase-4 inhibitors administered in combination with metformin result in an additive increase in the plasma concentration of active GLP-1
Migoya, E. M., Bergeron, R., Miller, J. L., Snyder, R. N. K., Tanen, M., Hilliard, D., Weiss, B., Larson, P., Gutierrez, M., Jiang, G., Liu, F., Pryor, K. A., Yao, J., Zhu, L., Holst, J. J., Deacon, C., Herman, G., Thornberry, N., Amatruda, J., Williams-Herman, D. & 2 others, , 1 Dec 2010, In: Clinical Pharmacology and Therapeutics. 88, 6, p. 801-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucokinase diabetes in 103 families from a country-based study in the Czech Republic: geographically restricted distribution of two prevalent GCK mutations
Pruhova, S., Dusatkova, P., Sumnik, Z., Kolouskova, S., Pedersen, Oluf Borbye, Hansen, Torben, Cinek, O. & Lebl, J., 1 Dec 2010, In: Pediatric Diabetes Online. 11, 8, p. 529-35 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Low birthweight and premature birth are both associated with type 2 diabetes in a random sample of middle-aged Danes
Pilgaard, K., Færch, K., Carstensen, B., Poulsen, P., Pisinger, C., Pedersen, Oluf Borbye, Witte, D. R., Hansen, Torben, Jørgensen, T. & Vaag, Allan, 1 Dec 2010, In: Diabetologia. 53, 12, p. 2526-30 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Physiologic characterization of type 2 diabetes-related loci
Grarup, Niels, Sparsø, T. & Hansen, Torben, 1 Dec 2010, In: Current Diabetes Reports. 10, 6, p. 485-97 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prenatal exposures to perfluorinated chemicals and anthropometric measures in infancy
Andersen, C. S., Fei, C., Gamborg, Michael Orland, Nohr, E. A., Sørensen, Thorkild I.A. & Olsen, J., 1 Dec 2010, In: American Journal of Epidemiology. 172, 11, p. 1230-7 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reduced gluconeogenesis and lactate clearance in Huntington's disease
Josefsen, K., Nielsen, S. M. B., Campos, A., Seifert, T., Hasholt, Lis Frydenreich, Nielsen, Jørgen Erik, Nørremølle, Anne, Skotte, Niels Henning, Secher, Niels H. & Quistorff, B., 1 Dec 2010, In: Neurobiology of Disease. 40, 3, p. 656-62 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Stata tip 92: Manual implementation of permutations and bootstraps
Ängquist, Lars, 1 Dec 2010, In: Stata Journal. 10, 4, p. 686-688 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sustained glucagon-like peptide-2 infusion is required for intestinal adaptation, and cessation reverses increased cellularity in rats with intestinal failure
Koopmann, M. C., Chen, X., Holst, Jens Juul & Ney, D. M., 1 Dec 2010, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 299, 6, p. G1222-30 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The levelling off of the obesity epidemic since the year 1999--a review of evidence and perspectives
Rokholm, B., Baker, J. L. & Sørensen, Thorkild I.A., 1 Dec 2010, In: Obesity Reviews. 11, 12, p. 835-46 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Treatment of insulin resistance and obesity by stimulating GLP-1 release
Hansen, Harald S., Diep, T. A., Holst, Jens Juul, Rosenkilde, Mette & Andersen, N. W., 29 Dec 2010, IPC No. A61K 31/23, Patent No. PCT/DK2010/050161, 24 Jun 2010Research output: Patent
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Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
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Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets
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Family and population-based studies of variation within the ghrelin receptor locus in relation to measures of obesity
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Determinants of plasma levels of proglucagon and the metabolic impact of glucagon receptor signalling: a UK Biobank study
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