Novo Nordisk Foundation Center for Basic Metabolic Research

  1. 2014
  2. Published

    Whole-genome bisulfite sequencing of multiple individuals reveals complementary roles of promoter and gene body methylation in transcriptional regulation

    Lou, S., Lee, H., Qin, H., Li, J., Gao, Z., Liu, X., Chan, L. L., Lam, V. K. L., So, W., Wang, Y., Lok, S., Wang, J., Ma, R. C. W., Tsui, S. K., Chan, J. C. N., Chan, T. & Yip, K. Y., 2014, In: Genome Biology (Online Edition). 15, 7, 21 p., 408.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Whole-genome sequence variation, population structure and demographic history of the Dutch population

    Francioli, L. C., Menelaou, A., Pulit, S. L., Van Dijk, F., Palamara, P. F., Elbers, C. C., Neerincx, P. B. T., Ye, K., Guryev, V., Kloosterman, W. P., Deelen, P., Abdellaoui, A., Van Leeuwen, E. M., Van Oven, M., Vermaat, M., Li, M., Laros, J. F. J., Karssen, L. C., Kanterakis, A., Amin, N. & 64 others, Hottenga, J. J., Lameijer, E., Kattenberg, M., Dijkstra, M., Byelas, H., Van Settenl, J., Van Schaik, B. D. C., Bot, J., Nijman, I. J., Renkens, I., Marscha, T., Schonhuth, A., Hehir-Kwa, J. Y., Handsaker, R. E., Polak, P., Sohail, M., Vuzman, D., Hormozdiari, F., Van Enckevort, D., Mei, H., Koval, V., Moed, M. H., Van der Velde, K. J., Rivadeneira, F., Estrada, K., Medina-Gomez, C., Isaacs, A., McCarroll, S. A., Beekrnan, M., De Craen, A. J. M., Suchiman, H. E. D., Hofman, A., Oostra, B., Uitterlinden, A. G., Willemsen, G., Plattee, M., Veldink, J. H., Van den Berg, L. H., Pitts, S. J., Potluri, S., Sundar, P., Cox, D. R., Sunyaev, S. R., Den Dunnen, J. T., Stoneking, M., De Knijff, P., Kayser, M., Li, Q., Li, Y., Du, Y., Chen, R., Cao, H., Li, N., Cao, S., Wang, J., Bovenberg, J. A., Peer, I., Slagboom, P. E., Van Duijn, C. M., Boomsma, D. I., Van Ommen, G. B., De Bakker, P. I. W., Swertz, M. A. & Wijmenga, C., 2014, In: Nature Genetics. 46, 8, p. 818-825 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Distal gastrectomy in pancreaticoduodenectomy is associated with accelerated gastric emptying, enhanced postprandial release of GLP-1, and improved insulin sensitivity

    Harmuth, S., Wewalka, M., Holst, Jens Juul, Nemecek, R., Thalhammer, S., Schmid, R., Sahora, K., Gnant, M. & Miholić, J., Jan 2014, In: Journal of Gastrointestinal Surgery. 18, 1, p. 52-9 8 p.

    Research output: Contribution to journalConference articleResearchpeer-review

  5. Published

    Effects of concentrated arabinoxylan and β-glucan compared with refined wheat and whole grain rye on glucose and appetite in subjects with the metabolic syndrome: a randomized study

    Hartvigsen, M. L., Gregersen, S., Lærke, H. N., Holst, Jens Juul, Bach Knudsen, K. E. & Hermansen, K., Jan 2014, In: European Journal of Clinical Nutrition. 68, 1, p. 84-90 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    GLP-1 responses are heritable and blunted in acquired obesity with high liver fat and insulin resistance

    Matikainen, N., Bogl, L. H., Hakkarainen, A., Lundbom, J., Lundbom, N., Kaprio, J., Rissanen, A., Holst, Jens Juul & Pietiläinen, K. H., Jan 2014, In: Diabetes Care. 37, 1, p. 242-51 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Impact of aspirin and statins on long-term survival in patients hospitalized with acute myocardial infarction complicated by heart failure: an analysis of 1706 patients

    Lewinter, C., Bland, J. M., Crouch, S., Cleland, J. G. F., Doherty, P., LeWinter, M. M., Køber, Lars Valeur, Hall, A. S. & Gale, C. P., Jan 2014, In: European Journal of Heart Failure. 16, 1, p. 95-102 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Postprandial responses of incretin and pancreatic hormones in non-diabetic patients with end-stage renal disease

    Idorn, T., Knop, Filip Krag, Jørgensen, M., Holst, Jens Juul, Hornum, Mads & Feldt-Rasmussen, Bo, Jan 2014, In: Nephrology, Dialysis, Transplantation. 29, 1, p. 119-27 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Systemic immunogenicity of para-Phenylenediamine and Diphenylcyclopropenone: two potent contact allergy-inducing haptens

    Svalgaard, J. D., Særmark, C., Dall, M., Buschard, K., Johansen, Jeanne Duus & Engkilde, K., Jan 2014, In: Immunologic Research. 58, 1, p. 40-50 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    The authors reply

    Idorn, T., Knop, Filip Krag, Jørgensen, M., Holst, Jens Juul, Hornum, Mads & Feldt-Rasmussen, Bo, Jan 2014, In: Kidney International. 85, 1, p. 212-3 2 p.

    Research output: Contribution to journalLetterResearchpeer-review

  11. Published

    Age-related and depot-specific changes in white adipose tissue of growth hormone receptor-null mice

    Sackmann-Sala, L., Berryman, D. E., Lubbers, E. R., Zhang, H., Vesel, C. B., Troike, K. M., Gosney, E. S., List, E. O. & Kopchick, J. J., 1 Jan 2014, In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 69, 1, p. 34-43 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Childhood Height and Body Mass Index Were Associated with Risk of Adult Thyroid Cancer in a Large Cohort Study

    Kitahara, C. M., Gamborg, Michael Orland, Berrington de González, A., Sørensen, Thorkild I.A. & Baker, J. L., 1 Jan 2014, In: Cancer Research. 74, 1, p. 235-242 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Genome-wide association study of sexual maturation in males and females highlights a role for body mass and menarche loci in male puberty

    The ReproGen Consortium, T. R. C., The Early Growth Genetics (EGG) Consortium, T. E. G. G. (. C., The Early Growth Genetics (EGG) Consortium, T. E. G. G. (. C., The ReproGen Consortium, T. R. C. & The GIANT Consortium, T. G. C., 1 Jan 2014, In: Human Molecular Genetics. 23, 16, p. 4452-4464 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Targeting the intestinal L-cell for obesity and type 2 diabetes treatment

    Albrechtsen, Nicolai Jacob Wewer, Kuhre, Rune Ehrenreich, Deacon, Carolyn F. & Holst, Jens Juul, 1 Jan 2014, In: Expert Review of Endocrinology & Metabolism. 9, 1, p. 61-72 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Type 2 diabetes susceptibility gene variants predispose to adult-onset autoimmune diabetes

    Lepola, Mette Andersen, Sterner, M., Forsén, T., Käräjämäki, A., Rolandsson, O., Forsblom, C., Groop, P. H., Lahti, K., Nilsson, P. M., Groop, L. & Tuomi, T., 1 Jan 2014, In: Diabetologia. 57, 9, p. 1859-1868 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Lysine deacetylase inhibition prevents diabetes by chromatin-independent immunoregulation and β-cell protection

    Christensen, D. P., Gysemans, C., Lundh, M., Dahllöf, M. S., Noesgaard, D., Schmidt, S. F., Mandrup, S., Birkbak, N., Workman, C., Piemonti, L., Blaabjerg, L., Monzani, V., Fossati, G., Mascagni, P., Paraskevas, S., Aikin, R. A., Billestrup, N., Grunnet, L. G., Dinarello, C. A., Mathieu, C. & 1 others, Mandrup-Poulsen, Thomas, 6 Jan 2014, In: Proceedings of the National Academy of Sciences of the United States of America. 111, 3, p. 1055-9 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Effects of chronic glucagon-like peptide-2 therapy during weaning in neonatal pigs

    Sigalet, D. L., de Heuvel, E., Wallace, L., Bulloch, E., Turner, J., Wales, P. W., Nation, P., Wizzard, P. R., Hartmann, Bolette, Assad, M. & Holst, Jens Juul, 10 Jan 2014, In: Regulatory Peptides. 188, p. 70-80 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Muscle specific miRNAs are induced by testosterone and independently upregulated by age

    Nielsen, S., Hvid, T., Kelly, M., Lindegaard, B., Dethlefsen, C., Winding, K., Mathur, N., Schéele, Camilla Charlotte Nielsen, Pedersen, Bente Klarlund & Laye, M. J., 23 Jan 2014, In: Frontiers in Physiology. 4, p. 1-11 11 p., 394.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    MTHFR C677T genotype and cardiovascular risk in a general population without mandatory folic acid fortification

    Husemoen, L. L. N., Skaaby, T., Jørgensen, T., Thuesen, B. H., Fenger, M., Grarup, N., Sandholt, C. H., Hansen, Torben, Pedersen, Oluf Borbye & Linneberg, Allan René, 24 Jan 2014, In: European Journal of Nutrition. 53, 7, p. 1549-59 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Identification of low-frequency and rare sequence variants associated with elevated or reduced risk of type 2 diabetes

    Steinthorsdottir, V., Thorleifsson, G., Sulem, P., Helgason, H., Grarup, N., Sigurdsson, A., Helgadottir, H. T., Johannsdottir, H., Magnusson, O. T., Gudjonsson, S. A., Justesen, J. M., Harder, M. N., Jørgensen, M. E., Christensen, C., Brandslund, I., Sandbæk, A., Lauritzen, T., Vestergaard, H., Linneberg, A., Jørgensen, T. & 14 others, Hansen, Torben, Daneshpour, M. S., Fallah, M., Hreidarsson, A. B., Sigurdsson, G., Azizi, F., Benediktsson, R., Masson, G., Helgason, A., Kong, A., Gudbjartsson, D. F., Pedersen, Oluf Borbye, Thorsteinsdottir, U. & Stefansson, K., 26 Jan 2014, In: Nature Genetics. 46, 3, p. 294-300 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Altered promoter methylation of PDK4, IL1 B, IL6, and TNF after Roux-en Y gastric bypass

    Kirchner, H., Nylen, C., Laber, S., Barrès, Romain, Yan, J., Krook, A., Zierath, Juleen R & Näslund, E., 28 Jan 2014, In: Surgery for Obesity and Related Diseases. 10, 4, p. 671-8 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    GLP-1 Amidation Efficiency Along the Length of the Intestine in Mice, Rats and Pigs and in GLP-1 Secreting Cell Lines

    Kuhre, Rune Ehrenreich, Albrechtsen, Nicolai Jacob Wewer, Windeløv, Johanne Agerlin, Svendsen, B., Hartmann, Bolette & Holst, Jens Juul, 31 Jan 2014, In: Peptides. 55, p. 52-57 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Body mass index in childhood and adult risk of primary liver cancer

    Berentzen, T. L., Gamborg, Michael Orland, Holst, C., Sørensen, Thorkild I.A. & Baker, J. L., Feb 2014, In: Journal of Hepatology. 60, 2, p. 325-30 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Effects of sitagliptin and metformin treatment on incretin hormone and insulin secretory responses to oral and "isoglycemic" intravenous glucose

    Vardarli, I., Arndt, E., Deacon, Carolyn F., Holst, Jens Juul & Nauck, M. A., Feb 2014, In: Diabetes. 63, 2, p. 663-74 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Generation of L cells in mouse and human small intestine organoids

    Petersen, N., Reimann, F., Bartfeld, S., Farin, H. F., Ringnalda, F. C., Vries, R. G. J., van den Brink, S., Clevers, H., Gribble, F. M. & de Koning, E. J. P., Feb 2014, In: Diabetes. 63, 2, p. 410-20 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Genetic and familial environmental effects on suicide attempts: A study of Danish adoptees and their biological and adoptive siblings

    Petersen, L., Sørensen, Thorkild I.A., Andersen, Per Kragh, Mortensen, P. B. & Hawton, K., Feb 2014, In: Journal of Affective Disorders. 155, p. 273-277 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    How do pregnancy-related weight changes and breastfeeding relate to maternal weight and BMI-adjusted waist circumference 7 y after delivery? Results from a path analysis

    Kirkegaard, H., Stovring, H., Rasmussen, K. M., Abrams, B., Sørensen, Thorkild I.A. & Nohr, E. A., Feb 2014, In: The American Journal of Clinical Nutrition. 99, 2, p. 312-319 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Impact of the reconstruction method on delayed gastric emptying after pylorus-preserving pancreaticoduodenectomy: a prospective randomized study

    Tamandl, D., Sahora, K., Prucker, J., Schmid, R., Holst, J., Miholic, J., Goetzinger, P., Gnant, M. & Holst, Jens Juul, Feb 2014, In: World Journal of Surgery. 38, 2, p. 465-75 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Mechanisms of changes in glucose metabolism and bodyweight after bariatric surgery

    Madsbad, Sten, Dirksen, C. & Holst, Jens Juul, Feb 2014, In: The Lancet Diabetes & Endocrinology. 2, 2, p. 152-64 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    The effect of referral for cardiac rehabilitation on survival following acute myocardial infarction: a comparison survival in two cohorts collected in 1995 and 2003

    Lewinter, C., Bland, J. M., Crouch, S., Doherty, P., Lewin, R. J., Køber, Lars Valeur, Hall, A. S. & Gale, C. P., Feb 2014, In: European Journal of Preventive Cardiology. 21, 2, p. 163-171 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Interplay between FGF21 and insulin action in the liver regulates metabolism

    Emanuelli, Brice, Vienberg, S. G., Smyth, G., Cheng, C., Stanford, K. I., Arumugam, Mani, Michael, M. D., Adams, A. C., Kharitonenkov, A. & Kahn, C. R., 3 Feb 2014, In: The Journal of Clinical Investigation. 124, 2, p. 515-27 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Young men with low birthweight exhibit decreased plasticity of genome-wide muscle DNA methylation by high-fat overfeeding

    Jacobsen, S. C., Gillberg, L., Bork-Jensen, J., Ribel-Madsen, R., Lara, E., Calvanese, V., Ling, C., Fernandez, A. F., Fraga, M. F., Poulsen, P., Brøns, C. & Vaag, Allan, 26 Feb 2014, In: Diabetologia. 57, 6, p. 1154-1158 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Adipose triglyceride lipase and g0/g1 switch gene 2: approaching proof of concept

    Nielsen, Thomas Svava & Møller, N., Mar 2014, In: Diabetes. 63, 3, p. 847-9 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Birth weight, childhood BMI and height in relation to mammographic density and breast cancer: Register based cohort study

    Andersen, Zorana Jovanovic, Baker, J. L., Bihrmann, K., Vejborg, I., Sørensen, Thorkild I.A. & Lynge, Elsebeth, Mar 2014, In: European Journal of Cancer. 50, Suppl S2, p. S75-S75 1 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  35. Published

    Defining the role of GLP-1 in the enteroinsulinar axis in type 2 diabetes using DPP-4 inhibition and GLP-1 receptor blockade

    Aulinger, B. A., Bedorf, A., Kutscherauer, G., de Heer, J., Holst, Jens Juul, Göke, B. & Schirra, J., Mar 2014, In: Diabetes. 63, 3, p. 1079-92 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Gating function of isoleucine-116 in TM-3 (position III:16/3.40) for the activity state of the CC-chemokine receptor 5 (CCR5)

    Steen, A., wbf943, wbf943, Thiele, S., Guo, D., Frimurer, Thomas Michael & Rosenkilde, Mette, Mar 2014, In: British Journal of Pharmacology. 171, 6, p. 1566-79 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

    Mahajan, A., Go, M. J., Zhang, W., Below, J. E., Gaulton, K. J., Ferreira, T., Horikoshi, M., Johnson, A. D., Ng, M. C. Y., Prokopenko, I., Saleheen, D., Wang, X., Zeggini, E., Abecasis, G. R., Adair, L. S., Almgren, P., Atalay, M., Aung, T., Baldassarre, D., Balkau, B. & 31 others, Bao, Y., Barnett, A. H., Barroso, I., Basit, A., Been, L. F., Beilby, J., Bell, G. I., Benediktsson, R., Bergman, R. N., Boehm, B. O., Boerwinkle, E., Bonnycastle, L. L., Burtt, N., Cai, Q., Campbell, H., Carey, J., Cauchi, S., Caulfield, M., Chan, J. C. N., Chang, L., Chang, T., Chang, Y., Charpentier, G., Chen, C., Chen, H., Chen, Y., Chia, K., Chidambaram, M., Chines, P. S., Jonsson, Anna Elisabet & Diabetes Genetics Replication and Meta-analysis (DIAGRAM) Consortium, D. G. R. A. M. (. C., Mar 2014, In: Nature Genetics. 46, 3, p. 234-44 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Glucose-dependent Insulinotropic Polypeptide: Blood Glucose Stabilizing Effects in Patients With Type 2 Diabetes

    Christensen, Mikkel Bring, Calanna, S., Holst, Jens Juul, Vilsbøll, T. & Knop, Filip Krag, Mar 2014, In: The Journal of clinical endocrinology and metabolism. 99, 3, p. E418-26 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Insulin resistance alters islet morphology in nondiabetic humans

    Mezza, T., Muscogiuri, G., Sorice, G. P., Clemente, G., Hu, J., Pontecorvi, A., Holst, Jens Juul, Giaccari, A. & Kulkarni, R. N., Mar 2014, In: Diabetes. 63, 3, p. 994-1007 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    The incretin effect does not differ in trained and untrained, young, healthy men

    Lund, M. T., Dalby, S., Hartmann, Bolette, Helge, Jørn Wulff, Holst, Jens Juul & Dela, Flemming, Mar 2014, In: Acta Physiologica. 210, 3, p. 565-72 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Variation in genes related to hepatic lipid metabolism and changes in waist circumference and body weight

    Meidtner, K., Fisher, E., Ängquist, Lars, Holst, C., Vimaleswaran, K. S., Boer, J. M. A., Halkjær, J., Masala, G., Ostergaard, J. N., Mortensen, L. M., van der A, D. L., Tjønneland, A., Palli, D., Overvad, K., Wareham, N. J., Loos, R. J. F., Sørensen, Thorkild I.A. & Boeing, H., Mar 2014, In: Genes & Nutrition. 9, p. 1-11 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Similar weight-adjusted insulin secretion and insulin sensitivity in short-duration late autoimmune diabetes of adulthood (LADA) and Type 2 diabetes: Action LADA 8

    Juhl, C. B., Bradley, U., Holst, Jens Juul, Leslie, R. D., Yderstraede, K. B., Hunter, S. & Action LADA Consortium, A. L. C., 15 Mar 2014, In: Diabetic Medicine. 31, 8, p. 941-945

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Increased metabolic flexibility and complexity in a long-lived growth hormone insensitive mouse model

    Lee Hong, S., Longo, K. A., Gosney, E. & Kopchick, J. J., 17 Mar 2014, In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 69 A, 3, p. 274-281 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Incretin Effect and Glucagon Responses to Oral and Intravenous Glucose in Patients with Maturity Onset Diabetes of the Young - Type 2 and Type 3

    Ostoft, S. H., Bagger, J. I., Hansen, Torben, Pedersen, Oluf Borbye, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, T., 27 Mar 2014, In: Diabetes. 63, 8, p. 2838-44 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    A Probabilistic Genome-Wide Gene Reading Frame Sequence Model

    Have, C. T. & Mørk, S., Apr 2014. 12 p.

    Research output: Contribution to conferencePaperResearchpeer-review

  46. Published

    A functional amino acid substitution in the glucose-dependent insulinotropic polypeptide receptor (GIPR) gene is associated with lower bone mineral density and increased fracture risk

    Torekov, Signe Sørensen, Harsløf, T., Rejnmark, L., Eiken, P., Jensen, Jens-Erik Beck, Herman, A. P., Hansen, Torben, Pedersen, Oluf Borbye, Holst, Jens Juul & Langdahl, B. L., Apr 2014, In: The Journal of clinical endocrinology and metabolism. 99, 4, p. E729-33 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    GLP-1/glucagon coagonism restores leptin responsiveness in obese mice chronically maintained on an obesogenic diet

    Clemmensen, Christoffer, Chabenne, J., Finan, B., Sullivan, L., Fischer, K., Küchler, D., Sehrer, L., Ograjsek, T., Hofmann, S. M., Schriever, S. C., Pfluger, P. T., Pinkstaff, J., Tschöp, M. H., Dimarchi, R. & Müller, T. D., Apr 2014, In: Diabetes. 63, 4, p. 1422-7 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Impact of oral vancomycin on gut microbiota, bile acid metabolism, and insulin sensitivity

    Vrieze, A., Out, C., Fuentes, S., Jonker, L., Reuling, I., Kootte, R. S., van Nood, E., Holleman, F., Knaapen, M., Romijn, J. A., Soeters, M. R., Blaak, E. E., Dallinga-Thie, G. M., Reijnders, D., Ackermans, M. T., Serlie, M. J., Knop, F. K., Holst, J. J., van der Ley, C., Kema, I. P. & 6 others, Zoetendal, E. G., de Vos, W. M., Hoekstra, J. B. L., Stroes, E. S., Groen, A. K. & Nieuwdorp, M., Apr 2014, In: Journal of Hepatology. 60, 4, p. 824-31 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Interaction between genetic predisposition to obesity and dietary calcium in relation to subsequent change in body weight and waist circumference

    Larsen, S. C., Ängquist, Lars, Ahluwalia, Tarun Veer Singh, Skaaby, T., Roswall, N., Tjønneland, A., Halkjær, J., Overvad, K., Pedersen, Oluf Borbye, Hansen, Torben, Linneberg, Allan René, Husemoen, L. L. N., Toft, Ulla Marie Nørgaard, Heitmann, Berit & Sørensen, Thorkild I.A., Apr 2014, In: The American Journal of Clinical Nutrition. 99, 4

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    KCNQ1 Long QT syndrome patients have hyperinsulinemia and symptomatic hypoglycemia

    Torekov, Signe Sørensen, Iepsen, E., Christiansen, M., Linneberg, Allan René, Pedersen, Oluf Borbye, Holst, Jens Juul, Kanters, Jørgen K. & Hansen, Torben, Apr 2014, In: Diabetes. 63, 4, p. 1315-1325 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Loss of melanocortin-4 receptor function attenuates HPA responses to psychological stress

    Ryan, K. K., Mul, J. D., Clemmensen, Christoffer, Egan, A. E., Begg, D. P., Halcomb, K., Seeley, R. J., Herman, J. P. & Ulrich-Lai, Y. M., Apr 2014, In: Psychoneuroendocrinology. 42, p. 98-105 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Loss-of-function mutations in SLC30A8 protect against type 2 diabetes

    Flannick, J., Thorleifsson, G., Beer, N. L., Jacobs, S. B. R., Grarup, N., Burtt, N. P., Mahajan, A., Fuchsberger, C., Atzmon, G., Benediktsson, R., Blangero, J., Bowden, D. W., Brandslund, I., Brosnan, J., Burslem, F., Chambers, J., Cho, Y. S., Christensen, C., Douglas, D. A., Duggirala, R. & 31 others, Dymek, Z., Farjoun, Y., Fennell, T., Fontanillas, P., Forsén, T., Gabriel, S., Glaser, B., Gudbjartsson, D. F., Hanis, C., Hansen, Torben, Hreidarsson, A. B., Hveem, K., Ingelsson, E., Isomaa, B., Johansson, S., Jørgensen, T., Jørgensen, M. E., Kathiresan, S., Kong, A., Kooner, J., Kravic, J., Laakso, M., Lee, J., Lind, L., Lindgren, C. M., Linneberg, Allan René, Masson, G., Meitinger, T., Ribel-Madsen, R., Pedersen, Oluf Borbye & Go-T2D Consortium, G. C., Apr 2014, In: Nature Genetics. 46, 4, p. 357-63 7 p.

    Research output: Contribution to journalLetterResearchpeer-review

  53. Published

    Pleiotropic effects of HNF1A rs1183910 in a population-based study of 60,283 individuals

    Allin, K. H. & Nordestgaard, Børge, Apr 2014, In: Diabetologia. 57, 4, p. 729-737 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Effect of IL-6 on the insulin sensitivity in patients with type 2 diabetes

    Harder-Lauridsen, N. M., Krogh-Madsen, Rikke, Holst, Jens Juul, Plomgaard, P., Leick, L., Pedersen, Bente Klarlund & Fischer, C. P., 1 Apr 2014, In: American Journal of Physiology: Endocrinology and Metabolism. 306, 7, p. E769-78 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    Fructose stimulates GLP-1 but not GIP secretion in mice, rats, and humans

    Kuhre, Rune Ehrenreich, Gribble, F. M., Hartmann, Bolette, Reimann, F., Windeløv, Johanne Agerlin, Rehfeld, Jens Frederik & Holst, Jens Juul, 1 Apr 2014, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 306, 7, p. G622-30 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    Evaluation of growth hormone (GH) action in mice: Discovery of GH receptor antagonists and clinical indications

    Kopchick, J. J., List, E. O., Kelder, B., Gosney, E. S. & Berryman, D. E., 5 Apr 2014, In: Molecular and Cellular Endocrinology. 386, 1-2, p. 34-45 12 p.

    Research output: Contribution to journalReviewResearchpeer-review

  57. Published

    Elimination and degradation of glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide in patients with end-stage renal disease

    Idorn, T., Knop, Filip Krag, Jørgensen, M. B., Christensen, Mikkel Bring, Holst, Jens Juul, Hornum, Mads & Feldt-Rasmussen, Bo, 8 Apr 2014, In: The Journal of clinical endocrinology and metabolism. 99, 7, p. 2457-66 10 p., jc20133809.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    Dose response of continuous subcutaneous infusion of recombinant glucagon-like peptide-1 in combination with metformin and sulphonylurea over 12 weeks in patients with type 2 diabetes mellitus

    Torekov, Signe Sørensen, Holst, Jens Juul & Ehlers, M. R., May 2014, In: Diabetes, Obesity and Metabolism. 16, 5, p. 451-6 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    Effects of AMPK activation on insulin sensitivity and metabolism in leptin-deficient ob/ob mice

    Zachariah Tom, R., Garcia-Roves, P. M., Sjögren, R. J. O., Jiang, L. Q., Holmström, M. H., Deshmukh, Atul Shahaji, Vieira, E., Chibalin, A. V., Björnholm, M. & Zierath, Juleen R, May 2014, In: Diabetes. 63, 5, p. 1560-71 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    Glutamate prevents intestinal atrophy via luminal nutrient sensing in a mouse model of total parenteral nutrition

    Xiao, W., Feng, Y., Holst, Jens Juul, Hartmann, Bolette, Yang, H. & Teitelbaum, D. H., May 2014, In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 28, 5, p. 2073-87 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published

    Is it acceptable to use animals to model obese humans? a critical discussion of two arguments against the use of animals in obesity research

    Lund, Thomas Bøker, Sørensen, Thorkild I.A., Olsson, I. A. S., Hansen, Axel Kornerup & Sandøe, Peter, May 2014, In: Journal of Medical Ethics. 40, 5, p. 320-324 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. Published

    Postprandial effects of test meals including concentrated arabinoxylan and whole grain rye in subjects with the metabolic syndrome: a randomised study

    Hartvigsen, M. L., Lærke, H. N., Overgaard, A., Holst, Jens Juul, Bach Knudsen, K. E. & Hermansen, K., May 2014, In: European Journal of Clinical Nutrition. 68, 5, p. 567-74 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    Quality control and conduct of genome-wide association meta-analyses

    Winkler, T. W., Day, F. R., Croteau-Chonka, D. C., Wood, A. R., Locke, A. E., Mägi, R., Ferreira, T., Fall, T., Graff, M., Justice, A. E., Luan, J., Gustafsson, S., Randall, J. C., Vedantam, S., Workalemahu, T., Kilpeläinen, T., Scherag, A., Esko, T., Kutalik, Z., Heid, I. M. & 2 others, Loos, Ruth & Genetic Investigation of Anthropometric Traits (GIANT) Consortium, G. I. O. A. T. (. C., May 2014, In: Nature Protocols (Online). 9, 5, p. 1192-1212 21 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. Published

    FXR is a molecular target for the effects of vertical sleeve gastrectomy

    Ryan, K. K., Tremaroli, V., Clemmensen, Christoffer, Kovatcheva-Datchary, P., Myronovych, A., Karns, R., Wilson-Pérez, H. E., Sandoval, D. A., Kohli, R., Bäckhed, F. & Seeley, R. J., 8 May 2014, In: Nature. 509, 7499, p. 183-8 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. Published

    Acute effects of monounsaturated fat on postprandial lipemia and gene expression in first-degree relatives of subjects with type 2 diabetes

    Pietraszek, A., Gregersen, S., Pedersen, S. B., Holst, Jens Juul & Hermansen, K., 14 May 2014, In: European Journal of Clinical Nutrition. 68, p. 1022-28 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  66. Published

    Glucagon responses to increasing oral loads of glucose and corresponding isoglycaemic intravenous glucose infusions in patients with type 2 diabetes and healthy individuals

    Bagger, J. I., Knop, Filip Krag, Lund, Asger Bach, Holst, Jens Juul & Vilsbøll, T., 31 May 2014, In: Diabetologia. 57, 8, p. 1270-25 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  67. Published

    Chronic glucocorticoid treatment increases de novo lipogenesis in visceral adipose tissue

    Vienberg, S. G. & Björnholm, M., Jun 2014, In: Acta Physiologica (Print). 211, 2, p. 257-9 3 p.

    Research output: Contribution to journalEditorialResearchpeer-review

  68. Published

    Deficiency of cardiac Acyl-CoA synthetase-1 induces diastolic dysfunction, but pathologic hypertrophy is reversed by rapamycin

    Paul, D. S., Grevengoed, Trisha Jean, Pascual, F., Ellis, J. M., Willis, M. S. & Coleman, R. A., Jun 2014, In: B B A - Reviews on Cancer. 1841, 6, p. 880-7 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. Published

    Dissecting adipose tissue lipolysis: molecular regulation and implications for metabolic disease

    Nielsen, Thomas Svava, Jessen, N., Jørgensen, J. O. L., Møller, N. & Lund, S., Jun 2014, In: Journal of Molecular Endocrinology. 52, 3, p. R199-R222 24 p.

    Research output: Contribution to journalReviewResearchpeer-review

  70. Published

    Glucose Stimulates GLP-1 Secretion from Isolated Perfused Rat Small Intestine by SGLT1 and GLUT2 Mediated Uptake, Causing V-gated Calcium Channel Activation

    Kuhre, Rune Ehrenreich, Frost, C. R., Svendsen, B. & Holst, Jens Juul, Jun 2014, In: Diabetes. 63, suppl 1, p. A491 1 p., Abstract no 1915-P.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  71. Published

    High heritability and genetic correlation of intravenous glucose- and tolbutamide-induced insulin secretion among non-diabetic family members of type 2 diabetic patients

    Gjesing, A. M. P., Hornbak, M., Allin, K. H., Ekstrøm, Claus Thorn, Urhammer, Søren Asger, Eiberg, Hans Rudolf Lytchoff, Pedersen, Oluf Borbye & Hansen, Torben, Jun 2014, In: Diabetologia. 57, 6, p. 1173-1181 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  72. Published

    Lessons from whole-exome sequencing in MODYX families

    Dusatkova, P., Fang, M., Pruhova, S., Gjesing, A. P., Cinek, O., Hansen, Torben, Pedersen, Oluf Borbye, Xu, X. & Lebl, J., Jun 2014, In: Diabetes Research and Clinical Practice. 104, 3, p. e72-4 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  73. Published

    MuRF1 activity is present in cardiac mitochondria and regulates reactive oxygen species production in vivo

    Mattox, T. A., Young, M. E., Rubel, C. E., Spaniel, C., Rodríguez, J. E., Grevengoed, Trisha Jean, Gautel, M., Xu, Z., Anderson, E. J. & Willis, M. S., Jun 2014, In: Journal of Bioenergetics and Biomembranes. 46, 3, p. 173-87 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. Published

    Hyperglucagonaemia analysed by glucagon sandwich ELISA: nonspecific interference or truly elevated levels?

    Albrechtsen, Nicolai Jacob Wewer, Hartmann, Bolette, Veedfald, Simon, Windeløv, Johanne Agerlin, Plamboeck, A., Bojsen-Møller, K. N., Idorn, T., Feldt-Rasmussen, Bo, Knop, Filip Krag, Vilsbøll, T., Madsbad, Sten, Deacon, Carolyn F. & Holst, Jens Juul, 3 Jun 2014, In: Diabetologia. 57, 9, p. 1919-1926 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. Published

    The role of hepatic lipids in hepatic insulin resistance and type 2 diabetes

    Perry, R. J., Samuel, V. T., Petersen, K. M. F. & Shulmann, G. I., 5 Jun 2014, In: Nature. 510, p. 84-91 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  76. Published

    Incretin secretion: direct mechanisms

    Balk-Møller, E., Holst, Jens Juul & Kuhre, Rune Ehrenreich, 12 Jun 2014, Diapedia: The living textbook of diabetes. European Association for the Study of Diabetes (EASD), p. 1-3 3 p.

    Research output: Chapter in Book/Report/Conference proceedingEncyclopedia chapterCommunication

  77. Published

    Glucose-Lowering Effects and Low Risk of Hypoglycemia in Patients With Maturity-Onset Diabetes of the Young When Treated With a GLP-1 Receptor Agonist: A Double-Blind, Randomized, Crossover Trial

    Ostoft, S. H., Bagger, J. I., Hansen, Torben, Pedersen, Oluf Borbye, Faber, Jens, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, T., 14 Jun 2014, In: Diabetes Care. 37, 7, p. 1797-1805 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  78. Published

    The impact of dipeptidyl peptidase 4 inhibition on incretin effect, glucose tolerance, and gastrointestinal-mediated glucose disposal in healthy subjects

    Rhee, N. A., Østoft, S. H., Holst, Jens Juul, Deacon, Carolyn F., Vilsbøll, T. & Knop, Filip Krag, 16 Jun 2014, In: European Journal of Endocrinology. 171, 3, p. 353-362 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  79. Published

    Stimulation of intestinal growth and function with DPP-IV inhibition in a mouse short bowel syndrome model

    Sueyoshi, R., Ignatoski, K. M. W., Okawada, M., Hartmann, Bolette, Holst, Jens Juul & Teitelbaum, D. H., 26 Jun 2014, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 307, 4, p. G410-19 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  80. Published

    Mapping Substance P Binding Sites on the Neurokinin-1 Receptor Using Genetic Incorporation of a Photoreactive Amino Acid

    Valentin-Hansen, L., Park, M., Huber, T., Grunbeck, A., Naganathan, S., Schwartz, Thue W. & Sakmar, T. P., 27 Jun 2014, In: The Journal of Biological Chemistry. 289, 26, p. 18045-54 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  81. Published

    Identification and characterization of human brown adipose tissue (BAT) content and metabolism in adults using [18F]-FDG PET/MR – a pilot study

    Johannesen, H. H., Löfgren, J., Donkin, I., Hansen, A. E., Loft, A., Højgaard, Liselotte & Kjær, Andreas, Jul 2014, In: E J N M M I Physics. 1, Suppl 1, 3 p., A68.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  82. Published

    META-Life: Biotechnologies, Synthetic Biology, Alife and the Arts

    Bureaud, A. (ed.), Malina, R. (ed.) & Whiteley, Louise (ed.), Jul 2014, (Leonardo).

    Research output: Book/ReportBookpeer-review

  83. Published

    Dynamic epigenetic responses to muscle contraction

    Rasmussen, M., Zierath, Juleen R & Barrès, Romain, 19 Jul 2014, In: Drug Discovery Today. 19, 7, p. 1010-4 5 p.

    Research output: Contribution to journalReviewResearchpeer-review

  84. Published

    Environmental factors affecting the expression of type IV pilus genes as well as piliation of Thermus thermophilus

    Salzer, R., Kern, T., Joos, F. & Averhoff, B., Aug 2014, In: FEMS Microbiology Letters. 357, 1, p. 56-62 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  85. Published

    Functional body composition and related aspects in research on obesity and cachexia: report on the 12th Stock Conference held on 6 and 7 September 2013 in Hamburg, Germany

    Müller, M. J., Baracos, V., Bosy-Westphal, A., Dulloo, A. G., Eckel, J., Fearon, K. C. H., Hall, K. D., Pietrobelli, A., Sørensen, Thorkild I.A., Speakman, J., Trayhurn, P., Visser, M. & Heymsfield, S. B., Aug 2014, In: Obesity Reviews. 15, 8, p. 640-656 17 p.

    Research output: Contribution to journalReviewResearchpeer-review

  86. Published

    Genetic susceptibility to type 2 diabetes and obesity: from genome-wide association studies to rare variants and beyond

    Grarup, N., Sandholt, C. H., Hansen, Torben & Pedersen, Oluf Borbye, Aug 2014, In: Diabetologia. 57, 8, p. 1528-41 14 p.

    Research output: Contribution to journalReviewResearchpeer-review

  87. Published

    High saturated fatty acid intake induces insulin secretion by elevating gastric inhibitory polypeptide levels in healthy individuals

    Itoh, K., Moriguchi, R., Yamada, Y., Fujita, M., Yamato, T., Oumi, M., Holst, Jens Juul & Seino, Y., Aug 2014, In: Nutrition Research. 34, 8, p. 653-60 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  88. Published

    Sex-specific effects of naturally occurring variants in the dopamine receptor D2 locus on insulin secretion and Type 2 diabetes susceptibility

    Guigas, B., de Leeuw van Weenen, J. E., van Leeuwen, N., Simonis-Bik, A. M., van Haeften, T. W., Nijpels, G., Houwing-Duistermaat, J. J., Beekman, M., Deelen, J., Havekes, L. M., Penninx, B. W. J. H., Vogelzangs, N., van 't Riet, E., Dehghan, A., Hofman, A., Witteman, J. C., Uitterlinden, A. G., Grarup, N., Jørgensen, T., Witte, D. R. & 15 others, Lauritzen, T., Hansen, Torben, Pedersen, Oluf Borbye, Hottenga, J., Romijn, J. A., Diamant, M., Kramer, M. H. H., Heine, R. J., Willemsen, G., Dekker, J. M., Eekhoff, E. M., Pijl, H., de Geus, E. J., Slagboom, P. E. & 't Hart, L. M., Aug 2014, In: Diabetic Medicine. 31, 8, p. 1001-8 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  89. Published

    Timing of motor milestones achievement and development of overweight in childhood: a study within the Danish National Birth Cohort

    Morgen, C. S., Nybo Andersen, Anne-Marie, Due, P., Neelon, S. B., Gamborg, Michael Orland & Sørensen, Thorkild I.A., Aug 2014, In: Pediatric Obesity. 9, 4, p. 239-48 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  90. Published

    Glycerol-3-phosphate acyltransferase-4-deficient mice are protected from diet-induced insulin resistance by the enhanced association of mTOR and rictor

    Zhang, C., Cooper, D. E., Grevengoed, Trisha Jean, Li, L. O., Klett, E. L., Eaton, J. M., Harris, T. E. & Coleman, R. A., 1 Aug 2014, In: American Journal of Physiology: Endocrinology and Metabolism. 307, 3, p. E305-15

    Research output: Contribution to journalJournal articleResearchpeer-review

  91. Published

    FTO genetic variants, dietary intake and body mass index: insights from 177 330 individuals

    Qi, Q., Oskari Kilpeläinen, T., Downer, M. K., Tanaka, T., Smith, C. E., Sluijs, I., Sonestedt, E., Chu, A. Y., Renström, F., Lin, X., Angquist, L. H., Huang, J., Liu, Z., Li, Y., Asif Ali, M., Xu, M., Ahluwalia, T. V. S., Boer, J. M. A., Chen, P., Daimon, M. & 89 others, Eriksson, J., Perola, M., Friedlander, Y., Gao, Y., Heppe, D. H. M., Holloway, J. W., Houston, D. K., Kanoni, S., Kim, Y., Laaksonen, M. A., Jääskeläinen, T., Lee, N. R., Lehtimäki, T., Lemaitre, R. N., Lu, W., Luben, R. N., Manichaikul, A., Männistö, S., Marques-Vidal, P., Monda, K. L., Ngwa, J. S., Perusse, L., van Rooij, F. J. A., Xiang, Y., Wen, W., Wojczynski, M. K., Zhu, J., Borecki, I. B., Bouchard, C., Cai, Q., Cooper, C., Dedoussis, G. V., Deloukas, P., Ferrucci, L., Forouhi, N. G., Hansen, Torben, Christiansen, L., Hofman, A., Johansson, I., Jørgensen, T., Karasawa, S., Khaw, K., Kim, M., Kristiansson, K., Li, H., Lin, X., Liu, Y., Lohman, K. K., Long, J., Mikkilä, V., Mozaffarian, D., North, K., Pedersen, Oluf Borbye, Raitakari, O., Rissanen, H., Tuomilehto, J., van der Schouw, Y. T., Uitterlinden, A. G., Carola Zillikens, M., Franco, O. H., Shyong Tai, E., Ou Shu, X., Siscovick, D. S., Toft, Ulla Marie Nørgaard, Monique Verschuren, W. M., Vollenweider, P., Wareham, N. J., Witteman, J. C. M., Zheng, W., Ridker, P. M., Kang, J. H., Liang, L., Jensen, M. K., Curhan, G. C., Pasquale, L. R., Hunter, D. J., Mohlke, K. L., Uusitupa, M., Adrienne Cupples, L., Rankinen, T., Orho-Melander, M., Wang, T., Chasman, D. I., Franks, P. W., Sørensen, Thorkild I.A., Hu, F. B., Loos, R. J. F., Nettleton, J. A. & Qi, L., 7 Aug 2014, In: Human Molecular Genetics. 23, 25, p. 6961-6972 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  92. Published

    Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age

    Deelen, J., Beekman, M., Uh, H-W., Broer, L., Ayers, K. L., Tan, Q., Kamatani, Y., Bennet, A. M., Tamm, R., Trompet, S., Guðbjartsson, D. F., Flachsbart, F., Rose, G., Viktorin, A., Fischer, K., Nygaard, M., Cordell, H. J., Crocco, P., van den Akker, E. B., Böhringer, S. & 67 others, Helmer, Q., Nelson, C. P., Saunders, G. I., Alver, M., Andersen-Ranberg, K., Breen, M. E., van der Breggen, R., Caliebe, A., Capri, M., Cevenini, E., Collerton, J. C., Dato, S., Davies, K., Ford, I., Gampe, J., Garagnani, P., de Geus, E. J. C., Harrow, J., van Heemst, D., Heijmans, B. T., Heinsen, F., Hottenga, J., Hofman, A., Jeune, B., Jonsson, P. V., Lathrop, M., Lechner, D., Martin-Ruiz, C., Mcnerlan, S. E., Mihailov, E., Montesanto, A., Mooijaart, S. P., Murphy, A., Nohr, E. A., Paternoster, L., Postmus, I., Rivadeneira, F., Ross, O. A., Salvioli, S., Sattar, N., Schreiber, S., Stefánsson, H., Stott, D. J., Tiemeier, H., Uitterlinden, A. G., Westendorp, R. G. J., Willemsen, G., Samani, N. J., Galan, P., Sørensen, Thorkild I.A., Boomsma, D. I., Jukema, J. W., Rea, I. M., Passarino, G., de Craen, A. J. M., Christensen, K., Nebel, A., Stefánsson, K., Metspalu, A., Magnusson, P., Blanché, H., Christiansen, L., Kirkwood, T. B. L., van Duijn, C. M., Franceschi, C., Houwing-Duistermaat, J. J. & Slagboom, P. E., 15 Aug 2014, In: Human Molecular Genetics. 23, 16, p. 4420-4432 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  93. Published

    Tarmbakterier kan have betydning for overvægt i barnealderen

    Fonvig, C. E., Pihl, A. F., Hansen, Torben, Pedersen, Oluf Borbye & Holm, Jens-Christian, 18 Aug 2014, In: Ugeskrift for Laeger. 176, p. 2-6 5 p., V03140171.

    Research output: Contribution to journalJournal articleResearchpeer-review

  94. Published

    Effect of high-fat diet on rat myometrium during pregnancy-isolated myometrial mitochondria are not affected

    Gam, C. M. B. F., Mortensen, Ole Hartvig, Qvortrup, Klaus, Damm, Peter & Quistorff, B., 21 Aug 2014, In: Pflügers Archiv - European Journal of Physiology. 467, 7, p. 1539-1549 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. Published

    Altered DNA Methylation and Differential Expression of Genes Influencing Metabolism and Inflammation in Adipose Tissue From Subjects With Type 2 Diabetes

    Nilsson, E., Jansson, P. A., Perfilyev, A., Volkov, P., Pedersen, M., Svensson, M. K., Poulsen, P., Ribel-Madsen, R., Pedersen, N. L., Almgren, P., Fadista, J., Rönn, T., Pedersen, Bente Klarlund, Schéele, Camilla Charlotte Nielsen, Vaag, Allan & Ling, C., Sep 2014, In: Diabetes. 63, 9, p. 2962-2976 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  96. Published

    Association of vitamin D status with arterial blood pressure and hypertension risk: a mendelian randomisation study

    Vimaleswaran, K. S., Cavadino, A., Berry, D. J., Jorde, R., Dieffenbach, A. K., Lu, C., Alves, A. C., Heerspink, H. J. L., Tikkanen, E., Eriksson, J., Wong, A., Mangino, M., Jablonski, K. A., Nolte, I. M., Houston, D. K., Ahluwalia, T. V. S., van der Most, P. J., Pasko, D., Zgaga, L., Thiering, E. & 31 others, Vitart, V., Fraser, R. M., Huffman, J. E., de Boer, R. A., Schöttker, B., Saum, K., McCarthy, M. I., Dupuis, J., Herzig, K., Sebert, S., Pouta, A., Laitinen, J., Kleber, M. E., Navis, G., Lorentzon, M., Jameson, K., Arden, N., Cooper, J. A., Acharya, J., Hardy, R., Raitakari, O., Ripatti, S., Billings, L. K., Lahti, J., Osmond, C., Penninx, B. W., Rejnmark, L., Lohman, K. K., Paternoster, L., Sørensen, Thorkild I.A. & LifeLines Cohort Study investigators, L. C. S. I., Sep 2014, In: The Lancet Diabetes & Endocrinology. 2, 9, p. 719-729 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  97. Published

    DNA methylation is altered in B and NK lymphocytes in obese and type 2 diabetic human

    Simar, D., Versteyhe, S., Donkin, I., Liu, J., Hesson, L., Nylander, V. C., Fossum, A. & Barrès, Romain, Sep 2014, In: Metabolism. 63, 9

    Research output: Contribution to journalJournal articleResearchpeer-review

  98. Published

    Genome-wide association analyses identify variants in developmental genes associated with hypospadias

    Geller, F., Feenstra, B., Carstensen, L., Pers, Tune H, van Rooij, I. A. L. M., Korberg, I. B., Choudhry, S., Karjalainen, J. M., Schnack, T. H., Hollegaard, M. V., Feitz, W. F. J., Roeleveld, N., Hougaard, D. M., Hirschhorn, J. N., Franke, L., Baskin, L. S., Nordenskjold, A., van der Zanden, L. F. M. & Melbye, M., Sep 2014, In: Nature Genetics. 46, 9, p. 957-+

    Research output: Contribution to journalJournal articleResearchpeer-review

  99. Published

    Glucometabolic hormones and cardiovascular risk markers in antipsychotic-treated patients

    Ebdrup, Bjørn, Knop, Filip Krag, Madsen, A., Mortensen, H. B., Søgaard, B., Holst, Jens Juul, Szecsi, P. B. & Lublin, H., Sep 2014, In: Journal of Clinical Psychiatry. 75, 9, p. e899-905 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  100. Published

    Obesity: Global trends in the prevalence of overweight and obesity

    Morgen, C. S. & Sørensen, Thorkild I.A., Sep 2014, In: Nature Reviews Endocrinology. 10, 9, p. 513-514 2 p.

    Research output: Contribution to journalComment/debateResearch

  101. Published

    Safety and efficacy of liraglutide in patients with type 2 diabetes and end-stage renal disease: an investigator-initiated, randomised, placebo-controlled trial

    Idorn, T., Knop, Filip Krag, Jorgensen, M. B., Jensen, T., Resuli, M., Hansen, P. M., Christensen, Karl Bang, Holst, Jens Juul, Hornum, M. & Feldt-Rasmussen, B., Sep 2014, In: Diabetologia. 57, 1 supplement, p. S370-S371 909.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review