- 2015
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Pancreatic Amylase and Lipase Plasma Concentrations Are Unaffected by Increments in Endogenous GLP-1 Levels Following Liquid Meal Tests
Sonne, David Peick, Vilsbøll, T. & Knop, Filip Krag, 2015, In: Diabetes Care. 38, 5, p. e71-2 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Post-surgical effects of Roux-En-Y gastric bypass on glucose homeostasis, intestinal morphology and L-cells in obese Göttingen minipigs
Barkholt, P., Vegge, A., Clausen, T. R., Birck, M. M., Fels, J. J., Støckel, M., Gögenur, Ismail, Eriksen, Thomas, Holst, Jens Juul, Hansen, Axel Kornerup, Thymann, Thomas, Jelsing, J., Sangild, Per Torp & Raun, K., 2015, In: Journal of Obesity and Bariatrics. 1, 1, 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prenatal exposure to systemic antibacterials and overweight and obesity in Danish schoolchildren: a prevalence study
Mor, A., Antonsen, S., Kahlert, J., Holsteen, V., Jørgensen, S., Holm-Pedersen, J., Sørensen, H. T., Pedersen, Oluf Borbye & Ehrenstein, V., 2015, In: International journal of obesity (2005). 39, 10, p. 1450-1455 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Prenatal exposure to vitamin-D from fortified margarine and milk and body size at age 7 years
Jensen, C. B., Gamborg, Michael Orland, Berentzen, T. L., Sørensen, Thorkild I.A. & Heitmann, Berit, 2015, In: European Journal of Clinical Nutrition. 69, 10, p. 1169-75 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prenatal parental separation and body weight, including development of overweight and obesity later in childhood
Hohwü, L., Zhu, J. L., Graversen, L., Li, J., Sørensen, Thorkild I.A. & Obel, C., 2015, In: PloS one. 10, 3, p. 1-10 10 p., e0119138.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prior AICAR stimulation increases insulin sensitivity in mouse skeletal muscle in an AMPK-dependent manner
Kjøbsted, Rasmus, Treebak, Jonas Thue, Fentz, J., Lantier, L., Viollet, B., Birk, Jesper Bratz, Schjerling, Peter, Björnholm, M., Zierath, Juleen R & Wojtaszewski, Jørgen F P, 2015, In: Diabetes. 64, 6, p. 2042-2055 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Proteome- and transcriptome-driven reconstruction of the human myocyte metabolic network and its use for identification of markers for diabetes
Väremo, L., Schéele, Camilla Charlotte Nielsen, Broholm, C., Mardinoglu, A., Kampf, C., Asplund, A., Nookaew, I., Uhlén, M., Pedersen, Bente Klarlund & Nielsen, J., 2015, In: Cell Reports. 11, 6, p. 921-33 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Public Science Communication
Whiteley, Louise, 2015, RCR – A Danish textbook for courses in Responsible Conduct of Research. Jensen, K. K., Whiteley, L. & Sandøe, P. (eds.). Frederiksberg, p. 90-107Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Education
- Published
R package for Sex-of-Parent-specific Transmission Ratio Distortion
Huang, L. O., 2015Research output: Non-textual form › Computer programme › Research
- Published
RCR - A Danish textbook for courses in Responsible Conduct of Research [1. ed.]
Jensen, Karsten Klint (ed.), Whiteley, Louise (ed.) & Sandøe, Peter (ed.), 2015, 1st edition ed. Frederiksberg: Department of Food and Resource Economics, University of Copenhagen. 107 p.Research output: Book/Report › Book
- Published
Reduced CD300LG mRNA tissue expression, increased intramyocellular lipid content and impaired glucose metabolism in healthy male carriers of Arg82Cys in CD300LG: a novel genometabolic cross-link between CD300LG and common metabolic phenotypes
Støy, J., Kampmann, U., Mengel, A., Magnusson, N. E., Jessen, N., Grarup, N., Rungby, Jørgen, Stødkilde-Jørgensen, H., Brandslund, I., Christensen, C., Hansen, Torben, Pedersen, Oluf Borbye & Møller, N., 2015, In: BMJ open diabetes research & care. 3, 1, p. 1-12 12 p., e000095.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reduction of insulinotropic properties of GLP-1 and GIP after glucocorticoid-induced insulin resistance
Eriksen, M., Jensen, D. H., Tribler, S., Holst, Jens Juul, Madsbad, Sten & Krarup, T., 2015, In: Diabetologia. 58, 5, p. 920-8 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Resistant starch and protein intake enhances fat oxidation and feelings of fullness in lean and overweight/obese women
Gentile, C. L., Ward, E., Holst, Jens Juul, Astrup, A., Ormsbee, M. J., Connelly, S. & Arciero, P. J., 2015, In: Nutrition Journal. 14, 10 p., 113.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Response to 'Energy balance measurement: when something is not better than nothing'
Dhurandhar, N. V., Schoeller, D. A., Brown, A. W., Heymsfield, S. B., Thomas, D., Sørensen, Thorkild I.A., Speakman, J. R., Jeansonne, M., Allison, D. B. & Energy Balance Measurement Working Group, E. B. M. W. G., 2015, In: International Journal of Obesity. 39, 7Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Response to Comments on Nolan et al. Insulin Resistance as a Physiological Defense Against Metabolic Stress: Implications for the Management of Subsets of Type 2 Diabetes. Diabetes 2015;64:673-686
Nolan, C. J., Ruderman, N. B., Kahn, S. E., Pedersen, Oluf Borbye & Prentki, M., 2015, In: Diabetes. 64, 10, p. e38-9 2 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Rev-erbα and the circadian transcriptional regulation of metabolism.
Gerhart-Hines, Zach & Lazar, M. A., 2015, In: Diabetes, Obesity and Metabolism Online. 17, S1, p. 12-16 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Roux-en-Y Gastric Bypass Surgery Induces Early Plasma Metabolomic and Lipidomic Alterations in Humans Associated with Diabetes Remission
Arora, T., Velagapudi, V., Pournaras, D. J., Welbourn, R., le Roux, C. W., Orešič, M. & Bäckhed, G. F., 2015, In: PLOS ONE. 10, 5, p. 1-10 10 p., e0126401.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Severe hypoglycaemia during treatment with sulphonylureas in patients with type 2 diabetes in the Capital Region of Denmark
Pilemann-Lyberg, S., Thorsteinsson, B., Snorgaard, O., Zander, M., drb459, drb459 & Røder, M. E., 2015, In: Diabetes Research and Clinical Practice. 110, 2, p. 202-7 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Signal Transduction Inhibitors as Promising Anticancer Agents
Kumar, R., Dos Santos, C., Ahluwalia, Tarun Veer Singh & Singh, S., 2015, In: BioMed Research International. 2015, p. 1-2 2 p., 584170.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
Site-specific programming of the host epithelial transcriptome by the gut microbiota
Sommer, F., Nookaew, I., Sommer, N., Fogelstrand, P. & Bäckhed, G. F., 2015, In: Genome Biology (Online Edition). 16, p. 1-15 15 p., 62.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Specific inhibition of bile acid transport alters plasma lipids and GLP-1
Rudling, M., Camilleri, M., Graffner, H., Holst, Jens Juul & Rikner, L., 2015, In: B M C Cardiovascular Disorders. 15, p. 1-8 8 p., 75.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The 2-monoacylglycerol moiety of dietary fat appears to be responsible for the fat-induced release of GLP-1 in humans.
Mandøe, M. J., Hansen, K. B., Hartmann, Bolette, Rehfeld, Jens Frederik, Holst, Jens Juul & Hansen, Harald S., 2015, In: The American Journal of Clinical Nutrition. 102, 3, p. 548-555 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Type 2 Diabetes Risk Allele of TMEM154-rs6813195 Associates with Decreased Beta Cell Function in a Study of 6,486 Danes
Balslev-Harder, M., Appel, E. V. R., Grarup, N., Gjesing, A. M. P., Ahluwalia, Tarun Veer Singh, Jørgensen, T., Christensen, C., Brandslund, I., Linneberg, Allan René, Sørensen, Thorkild I.A., Pedersen, Oluf Borbye & Hansen, Torben, 2015, In: PLOS ONE. 10, 3, p. 1-13 13 p., e0120890.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Use of Gastrostomy Tube for the Long-Term Remission of Hyperinsulinemic Hypoglycemia After Roux-en-y Gastric Bypass: A Case Report
Craig, C., Lamendola, C., Holst, Jens Juul, Deacon, Carolyn F. & McLaughlin, T., 2015, In: AACE Clinical Case Reports. 1, 2, p. e84-e87 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The glucagon-like peptide-1 receptor agonist liraglutide reduces jejunostomy output and improves intestinal absorption in short bowel syndrome patients with intestinal failure: A pilot study
Hvistendahl, M., Brandt, C. F., Tribler, S., Naimi, R., Hartmann, B., Holst, Jens Juul, Rehfeld, Jens Frederik, Hornum, M., Andersen, Jens Rikardt, Mortensen, P. B. & Jeppesen, P. B., 2015. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
- Published
The gut microbiome in cardio-metabolic health
Hansen, T. H., Gøbel, R. J., Hansen, Torben & Pedersen, Oluf Borbye, 2015, In: Genome Medicine. 7, p. 1-16 16 p., 33.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The gut microbiota modulates host amino acid and glutathione metabolism in mice
Mardinoglu, A., Shoaie, S., Bergentall, M., Ghaffari, P., Zhang, C., Larsson, E., Bäckhed, G. F. & Nielsen, J., 2015, In: Molecular Systems Biology. 11, 10, p. 1-15 15 p., 834.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The influence of glucagon on postprandial hyperglycaemia in children 5 years after onset of type 1 diabetes
Fredheim, S., Andersen, M. M., Pörksen, S., Nielsen, L. B., Pipper, C., Hansen, L., Holst, Jens Juul, Thomsen, J., Johannesen, Jesper, Mortensen, H. B. & Svensson, Jannet, 2015, In: Diabetologia. 58, 4, p. 828-34 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation
Kato, N., Loh, M., Takeuchi, F., Verweij, N., Wang, X., Zhang, W., Kelly, T. N., Saleheen, D., Lehne, B., Mateo Leach, I., Drong, A. W., Abbott, J., Wahl, S., Tan, S-T., Scott, W. R., Campanella, G., Chadeau-Hyam, M., Afzal, U., Ahluwalia, T. V. S., Bonder, M. J. & 31 others, , 2015, In: Nature Genetics. 47, 11, p. 1282-93 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Treatment with a GLP-1 receptor agonist diminishes the decrease in free plasma leptin during maintenance of weight loss
Iepsen, E. W., Lundgren, J., Dirksen, C., Jensen, J., Pedersen, Oluf Borbye, Hansen, Torben, Madsbad, Sten, Holst, Jens Juul & Torekov, Signe Sørensen, 2015, In: International journal of obesity (2005). 39, 5, p. 834-41 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tumor suppressor ASXL1 is essential for the activation of INK4B expression in response to oncogene activity and anti-proliferative signals
Wu, X., Bekker-Jensen, I. H., Christensen, J., Rasmussen, K. D., Sidoli, S., Qi, Y., Kong, Y., Wang, X., Cui, Y., Xiao, Z., Xu, G., Williams, K., Rappsilber, J., Sønderby, C. K., Winther, Ole, Jensen, O. N. & Helin, K., 2015, In: Cell Research. 25, p. 1205-1218 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Type 2 diabetes mellitus
DeFronzo, R. A., Ferrannini, E., Groop, L., Henry, R. R., Herman, W. H., Holst, Jens Juul, Hu, F. B., Kahn, C. R., Raz, I., Shulmann, G. I., Simonson, D. C., Testa, M. A. & Weiss, R., 2015, In: Nature Reviews. Disease Primers. 1, 22 p., 15019.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Uncovering the genetic history of the present-day greenlandic population
Moltke, Ida, Fumagalli, M., Korneliussen, Thorfinn Sand, Crawford, J. E., Bjerregaard, P., Jørgensen, M. E., Grarup, N., Gulløv, H. C., Linneberg, Allan René, Pedersen, Oluf Borbye, Hansen, Torben, Nielsen, Rasmus & Albrechtsen, Anders, 2015, In: American Journal of Human Genetics. 96, 1, p. 54-69 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Use of Antibiotics and Risk of Type 2 Diabetes: A Population-Based Case-Control Study
Mikkelsen, K. H., Knop, Filip Krag, Frost, M., Hallas, J. & Pottegård, A., 2015, In: Journal of Clinical Endocrinology and Metabolism. 100, 10, p. 3633-40 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Whole exome sequencing identifies frequent somatic mutations in cell-cell adhesion genes in chinese patients with lung squamous cell carcinoma
Li, C., Gao, Z., Li, F., Li, X., Sun, Y., Wang, M., Li, D., Wang, R., Li, F., Fang, R., Pan, Y., Luo, X., He, J., Zheng, L., Xia, J., Qiu, L., He, J., Ye, T., Zhang, R., He, M. & 32 others, , 2015, In: Scientific Reports. 5, 11 p., 14237 .Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A rationally designed monomeric peptide triagonist corrects obesity and diabetes in rodents
Finan, B., Yang, B., Ottaway, N., Smiley, D. L., Ma, T., Clemmensen, C., Chabenne, J., Zhang, L., Habegger, K. M., Fischer, K., Campbell, J. E., Sandoval, D., Seeley, R. J., Bleicher, K., Uhles, S., Riboulet, W., Funk, J., Hertel, C., Belli, S., Sebokova, E. & 9 others, , Jan 2015, In: Nature Medicine. 21, 1, p. 27-36 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of moderate- and high-intensity acute exercise on appetite in obese individuals
Martins, C., Stensvold, D., Finlayson, G., Holst, Jens Juul, Wisloff, U., Kulseng, B., Morgan, L. & King, N. A., Jan 2015, In: Medicine and Science in Sports and Exercise. 47, 1, p. 40-8 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GPR40 (FFAR1) – Combined Gs and Gq signaling in vitro is associated with robust incretin secretagogue action ex vivo and in vivo
Pedersen, M. H., Bentsen, M. A., Husted, Anna Sofie, Ekberg, J. P., Wright, M. J., Di Salvo, J., Weinglass, A. B., Engelstoft, M. S., Madsen, A. N., Lückmann, Michael, Miller, M. W., Trujillo, M. E., Frimurer, Thomas Michael, Holst, Birgitte, Howard, A. D. & Schwartz, Thue W., Jan 2015, In: Molecular Metabolism. 4, 1, p. 3-14 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic and environmental transactions underlying the association between physical fitness/physical exercise and body composition
Johnson, W., de Ruiter, I., Kyvik, K. O., Murray, A. L. & Sørensen, Thorkild I.A., Jan 2015, In: Behavior Genetics. 45, 1, p. 84-105 22 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucose-Dependent Insulinotropic Polypeptide Augments Glucagon Responses to Hypoglycemia in Type 1 Diabetes
Christensen, Mikkel Bring, Calanna, S., wbf943, wbf943, Kristensen, P. L., Rosenkilde, Mette, Faber, Jens, Purrello, F., van Hall, Gerrit, Holst, Jens Juul, Vilsbøll, T. & Knop, Filip Krag, Jan 2015, In: Diabetes. 64, 1, p. 72-78 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Habitual sleep duration is associated with BMI and macronutrient intake and may be modified by CLOCK genetic variants
Dashti, H. S., Follis, J. L., Smith, C. E., Tanaka, T., Cade, B. E., Gottlieb, D. J., Hruby, A., Jacques, P. F., Lamon-Fava, S., Richardson, K., Saxena, R., Scheer, F. A. J. L., Kovanen, L., Bartz, T. M., Perälä, M-M., Jonsson, A. E., Frazier-Wood, A. C., Kalafati, I-P., Mikkilä, V., Partonen, T. & 34 others, , Jan 2015, In: The American Journal of Clinical Nutrition. 101, 1, p. 135-43 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification and Functional Characterization of G6PC2 Coding Variants Influencing Glycemic Traits Define an Effector Transcript at the G6PC2-ABCB11 Locus
Mahajan, A., Sim, X., Ng, H. J., Manning, A., Rivas, M. A., Highland, H. M., Locke, A. E., Grarup, N., Im, H. K., Cingolani, P., Flannick, J., Fontanillas, P., Fuchsberger, C., Gaulton, K. J., Teslovich, T. M., Rayner, N. W., Robertson, N. R., Beer, N. L., Rundle, J. K., Bork-Jensen, J. & 31 others, , Jan 2015, In: P L o S Genetics. 11, 1, p. 1-25 25 p., e1004876.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Insights into the role of the microbiome in obesity and type 2 diabetes
Hartstra, A. V., Bouter, K. E. C., Bäckhed, G. F. & Nieuwdorp, M., Jan 2015, In: Diabetes Care. 38, 1, p. 159-65 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interplay between FGF21 and insulin action in the liver regulates metabolism
Emanuelli, Brice, Vienberg, S. G., Smyth, G., Cheng, C., Stanford, K. I., Arumugam, Mani, Michael, M. D., Adams, A. C., Kharitonenkov, A. & Kahn, C. R., Jan 2015, In: The Journal of Clinical Investigation. 125, 1, p. 458Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Prediction of adolescent and adult adiposity outcomes from early life anthropometrics
Graversen, L., Sørensen, Thorkild I.A., Gerds, Thomas Alexander, Petersen, L., Sovio, U., Kaakinen, M., Sandbaek, A., Laitinen, J., Taanila, A., Pouta, A., Järvelin, M. & Obel, C., Jan 2015, In: Obesity. 23, 1, p. 162-169 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Restoration of the insulinotropic effect of glucose-dependent insulinotropic polypeptide contributes to the antidiabetic effect of dipeptidyl peptidase-4 inhibitors
Aaboe, K., Akram, S., Deacon, Carolyn F., Holst, Jens Juul, Madsbad, Sten & Krarup, T., Jan 2015, In: Diabetes, Obesity and Metabolism. 17, 1, p. 74-81 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Whey-reduced weight gain is associated with a temporary growth reduction in young mice fed a high-fat diet
Christensen, B. T., Madsen, A. N., Hansen, Axel Kornerup & Hellgren, L. I., Jan 2015, In: Journal of Nutritional Biochemistry. 26, 1, p. 9-15 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Diabetes mellitus and metabolic syndrome
Ortega, E., Martín-Cordero, L., Garcia-Roves, P. M., Chicco, A. J., Gonzalez-Franquesa, A. & Marado, D., 1 Jan 2015, Biomarkers of Cardiometabolic Risk, Inflammation and Disease. Springer, p. 55-79 25 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Novel combinatorial therapies involving leptin: Opportunities for mechanistic advances and therapeutic translation in human diseases
Müller, T. D., Clemmensen, Christoffer, Finan, B., Dimarchi, R. D. & Tschöp, M. H., 1 Jan 2015, Leptin: Regulation and Clinical Applications. Springer, p. 267-279 13 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
HDAC Inhibitor-Mediated Beta-Cell Protection Against Cytokine-Induced Toxicity Is STAT1 Tyr701 Phosphorylation Independent
Dahllöf, M. S., Christensen, D. P., Harving, M., Wagner, B. K., Mandrup-Poulsen, Thomas & Lundh, M., 13 Jan 2015, In: Journal of Interferon & Cytokine Research. 35, 1, p. 63-70 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Erratum:Skeletal muscle PGC-1α1 modulates kynurenine metabolism and mediates resilience to stress-induced depression (Cell (2014) 159 (33-45))
Agudelo, L. Z., Femenía, T., Orhan, F., Porsmyr-Palmertz, M., Goiny, M., Martinez-Redondo, V., Correia, J. C., Izadi, M., Bhat, M., Schuppe-Koistinen, I., Pettersson, A., Ferreira, D. M. S., Krook, A., Barrès, Romain, Zierath, Juleen R, Erhardt, S., Lindskog, M. & Ruas, J. L., 15 Jan 2015, In: Cell. 160, 1-2, 1 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Sensing of triacylglycerol in the gut: different mechanisms for fatty acids and 2-monoacylglycerol
Kleberg, K., Jacobsen, A. K., Ferreira, J. G., Windeløv, Johanne Agerlin, Rehfeld, Jens Frederik, Holst, Jens Juul, de Araujo, I. E. & Hansen, Harald S., 16 Jan 2015, In: The Journal of Physiology. 593, 8, p. 2097-109 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Stability of glucagon-like peptide-1 and glucagon in human plasma
Albrechtsen, Nicolai Jacob Wewer, Bak, M. J., Hartmann, Bolette, Christensen, L. W., Kuhre, Rune Ehrenreich, Deacon, Carolyn F. & Holst, Jens Juul, 16 Jan 2015, In: Endocrine Connections. 4, 1, p. 50-57 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The VGF-Derived Neuropeptide TLQP-21 Shows No Impact on Hormone Secretion in the Isolated Perfused Rat Pancreas
Christiansen, Charlotte Bayer, Svendsen, B. & Holst, Jens Juul, 20 Jan 2015, In: Hormone and Metabolic Research. 47, 07, p. 537-43 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility
Wessel, J., Chu, A. Y., Willems, S. M., Wang, S., Yaghootkar, H., Brody, J. A., Dauriz, M., Hivert, M-F., Raghavan, S., Lipovich, L., Hidalgo, B., Fox, K., Huffman, J. E., An, P., Lu, Y., Rasmussen-Torvik, L. J., Grarup, N., Ehm, M. G., Li, L., Baldridge, A. S. & 31 others, , 29 Jan 2015, In: Nature Communications. 6, p. 5897Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Peptidomics combined with cDNA library unravel the diversity of centipede venom
Rong, M., Yang, S., Wen, B., Mo, G., Kang, D., Liu, J., Lin, Z., Jiang, W., Li, B., Du, C., Yang, S., Jiang, H., Feng, Q., Xu, X., Wang, J. & Lai, R., 30 Jan 2015, In: Journal of Proteomics. 114, 1, p. 28-37 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of acute exercise on pancreatic endocrine function in subjects with type 2 diabetes
Knudsen, S. H., Karstoft, K., Winding, K., Holst, Jens Juul, Pedersen, Bente Klarlund & Solomon, T., Feb 2015, In: Diabetes, Obesity and Metabolism. 17, 2, p. 207-210 4 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism
Hu, Z., Zhu, D., Wang, W., Li, W., Jia, W., Zeng, X., Ding, W., Yu, L., Wang, X., Wang, L., Shen, H., Zhang, C., Liu, H., Liu, X., Zhao, Y., Fang, X., Li, S., Chen, W., Tang, T., Fu, A. & 16 others, , Feb 2015, In: Nature Genetics. 47, 2, p. 158-63, 2 unpag. pages 8 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Intact Pituitary Function is Decisive for the Catabolic Response to TNF-α: Studies of Protein, Glucose and Fatty Acid Metabolism in Hypopituitary and Healthy Subjects
Bach, E., Møller, A. B., Jørgensen, J. O. L., Vendelbo, M. H., Jessen, N., Olesen, J. F., Pedersen, S. B., Nielsen, Thomas Svava & Møller, N., Feb 2015, In: The Journal of clinical endocrinology and metabolism. 100, 2, p. 578-86 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Maternal salivary cortisol levels during pregnancy are positively associated with overweight children
Hohwü, L., Henriksen, T. B., Grønborg, T. K., Hedegaard, M., Sørensen, Thorkild I.A. & Obel, C., Feb 2015, In: Psychoneuroendocrinology. 52, p. 143-152 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular Mechanisms of Glucose-Stimulated GLP-1 Secretion From Perfused Rat Small Intestine
Kuhre, Rune Ehrenreich, Frost, C. R., Svendsen, B. & Holst, Jens Juul, Feb 2015, In: Diabetes. 64, 2, p. 370-382 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Over-expression of Follistatin-like 3 attenuates fat accumulation and improves insulin sensitivity in mice
Brandt, C., Hansen, R. H., Hansen, J. B., Olsen, C. H., Galle, P., Mandrup-Poulsen, Thomas, Gehl, Julie, Pedersen, Bente Klarlund & Hojman, P., Feb 2015, In: Metabolism. 64, 2, p. 283-295 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Updates in weight loss surgery and gastrointestinal peptides
Svane, M. S., Bojsen-Møller, K. N., Madsbad, Sten & Holst, Jens Juul, Feb 2015, In: Current Opinion in Endocrinology, Diabetes and Obesity. 22, 1, p. 21-8 8 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
First report on intraoperative vector flow imaging of the heart among patients with healthy and diseased aortic valves
Hansen, Kristoffer Lindskov, Møller-Sørensen, H., Pedersen, M. M., Hansen, P. M., Kjærgaard, Jesper, Lund, Jens, Nilsson, J. C., Jensen, J. A. & Nielsen, Michael Bachmann, 1 Feb 2015, In: Ultrasonics. 56, p. 243-250 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In vivo efficacy of HD0471953: A novel GPR119 agonist for the treatment of type 2 diabetes mellitus
'T Hart, L. M., Fritsche, A., Nijpels, G., Van Leeuwen, N., Donnelly, L. A., Dekker, J. M., Alssema, M., Fadista, J., Carlotti, F., Gjesing, A. P., Palmer, C. N., Van Haeften, T. W., Herzberg-Schäfer, S. A., Simonis-Bik, A. M., Houwing-Duistermaat, J. J., Helmer, Q., Deelen, J., Guigas, B., Hansen, T., MacHicao, F. & 14 others, , 1 Feb 2015, In: Diabetes Technology & Therapeutics. 17, p. S131-S133Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
GLP-1 defects in diabetes
Janus, C., Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, 2 Feb 2015Research output: Other contribution › Net publication - Internet publication › Research › peer-review
- Published
Genetic studies of body mass index yield new insights for obesity biology
Locke, A. E., Kahali, B., Berndt, S. I., Justice, A. E., Pers, T. H., Day, F. R., Powell, C., Vedantam, S., Buchkovich, M. L., Yang, J., Croteau-Chonka, D. C., Esko, T., Fall, T., Ferreira, T., Gustafsson, S., Kutalik, Z., Luan, J., Mägi, R., Randall, J. C., Winkler, T. W. & 31 others, , 12 Feb 2015, In: Nature. 518, 7538, p. 197-206 24 p., 14177.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A novel common variant in DCST2 is associated with length in early life and height in adulthood
van der Valk, R. J. P., Kreiner-Møller, E., Kooijman, M. N., Guxens, M., Stergiakouli, E., Sääf, A., Bradfield, J. P., Geller, F., Hayes, M. G., Cousminer, D. L., Körner, A., Thiering, E., Curtin, J. A., Myhre, R., Huikari, V., Joro, R., Kerkhof, M., Warrington, N. M., Pitkänen, N., Ntalla, I. & 31 others, , 15 Feb 2015, In: Human Molecular Genetics. 24, 4, p. 1155-68 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Optimisation of in silico derived 2-aminobenzimidazole hits as unprecedented selective kappa opioid receptor agonists
Sasmal, P. K., Krishna, C. V., Sudheerkumar Adabala, S., Rawoof, K. A., Thadi, A., Sukumar, K. P., Cheera, S., Abbineni, C., Rao, K. V. L. N., Prasanthi, A., Nijhawan, K., Jaleel, M., Ramachandran Iyer, L., Chaitanya, T. K., Tiwari, N. K., Krishna, N. L., Potluri, V., Khanna, I., Frimurer, T. M., Lückmann, M. & 3 others, , 15 Feb 2015, In: Bioorganic & Medicinal Chemistry Letters. 25, 4, p. 887-92 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interactions of Lipid Genetic Risk Scores with Estimates of Metabolic Health in a Danish Population
Justesen, Johanne Marie, Allin, K. H., Sandholt, C. H., Borglykke, A., Krarup, N. T., Grarup, N., Linneberg, Allan René, Jørgensen, T., Hansen, Torben & Pedersen, Oluf Borbye, 24 Feb 2015, In: Circulation. Cardiovascular genetics. 8, p. 465-72 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
AMP-activated protein kinase controls exercise training- and AICAR-induced increases in SIRT3 and MnSOD
Brandauer, J., Andersen, M. A., Kellezi, H., Risis, S., Frøsig, C., Vienberg, S. G. & Treebak, Jonas Thue, Mar 2015, In: Frontiers in Physiology. 6, 16 p., 85.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An Analysis of Cosecretion and Coexpression of Gut Hormones From Male Rat Proximal and Distal Small Intestine
Svendsen, B., Pedersen, Jens, Albrechtsen, Nicolai Jacob Wewer, Hartmann, Bolette, Toräng, S., Rehfeld, Jens Frederik, Poulsen, Steen Seier & Holst, Jens Juul, Mar 2015, In: Endocrinology. 156, 3, p. 847-857 11 p., en20141710.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Circulating miR-192 and miR-193b are markers of prediabetes and are modulated by an exercise intervention
Párrizas, M., Brugnara, L., Esteban, Y., González-Franquesa, A., Canivell, S., Murillo, S., Gordillo-Bastidas, E., Cussó, R., Cadefau, J. A., García-Roves, P. M., Servitja, J. & Novials, A., Mar 2015, In: The Journal of clinical endocrinology and metabolism. 100, 3, p. E407-15Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Clearance of glucoregulatory peptide hormones during haemodialysis and haemodiafiltration in non-diabetic end-stage renal disease patients
Jørgensen, M. B., Idorn, T., Knop, Filip Krag, Holst, Jens Juul, Hornum, Mads & Feldt-Rasmussen, Bo, Mar 2015, In: Nephrology, Dialysis, Transplantation. 30, 3, p. 513-20 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
DISEASES: Text mining and data integration of disease-gene associations
Pletscher-Frankild, S., Pallejà, A., Tsafou, K., Binder, J. X. & Jensen, Lars Juhl, Mar 2015, In: Methods. 74, p. 83-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dual melanocortin-4 receptor and GLP-1 receptor agonism amplifies metabolic benefits in diet-induced obese mice
Clemmensen, Christoffer, Finan, B., Fischer, K., Tom, R. Z., Legutko, B., Sehrer, L., Heine, D., Grassl, N., Meyer, C. W., Henderson, B., Hofmann, S. M., Tschöp, M. H., Van der Ploeg, L. H. T. & Müller, T. D., Mar 2015, In: EMBO Molecular Medicine. 7, 3, p. 288-98 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Improvements in glucose metabolism early after gastric bypass surgery are not explained by increases in total bile acids and fibroblast growth factor 19 concentrations
Jørgensen, N. B., Dirksen, C., Bojsen-Møller, K. N., Kristiansen, V. B., Wulff, B. S., Rainteau, D., Humbert, L., Rehfeld, Jens Frederik, Holst, Jens Juul, Madsbad, Sten & Clausen, T. R., Mar 2015, In: The Journal of clinical endocrinology and metabolism. 100, 3, p. E396-406 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Incretin effect after oral amino Acid ingestion in humans
Lindgren, O., Pacini, G., Tura, A., Holst, Jens Juul, Deacon, Carolyn F. & Ahrén, B., Mar 2015, In: The Journal of clinical endocrinology and metabolism. 100, 3, p. 1172-6 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Insulin resistance as a physiological defense against metabolic stress: implications for the management of subsets of type 2 diabetes
Nolan, C. J., Ruderman, N. B., Kahn, S. E., Pedersen, Oluf Borbye & Prentki, M., Mar 2015, In: Diabetes. 64, 3, p. 673-86 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Placenta accreta: adherent placenta due to Asherman syndrome
pjx571, pjx571, Langhoff-Roos, J., Kjer, J. J. & Istre, O., Mar 2015, In: Clinical Case Reports. 3, 3, p. 175 178 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The gut microbiota engages different signaling pathways to induce Duox2 expression in the ileum and colon epithelium
Sommer, F. & Bäckhed, G. F., Mar 2015, In: Mucosal Immunology. 8, 2, p. 372-9 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Immediate enhancement of first-phase insulin secretion and unchanged glucose effectiveness in patients with type 2 diabetes after Roux-en-Y gastric bypass
Martinussen, C., Bojsen-Moller, K. N., Dirksen, C., Jacobsen, S. H., Jørgensen, N. B., Kristiansen, V. B., Holst, Jens Juul & Madsbad, Sten, 15 Mar 2015, In: American Journal of Physiology: Endocrinology and Metabolism. 308, 6, p. E535-44 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Contribution of common non-synonymous variants in PCSK1 to body-mass index variation and risk of obesity: a systematic review and meta-analysis with evidence from up to 331,175 individuals
Nead, K. T., Li, A., Wehner, M. R., Neupane, B., Gustafsson, S., Butterworth, A., Engert, J. C., Davis, A. D., Hegele, R. A., Miller, R., den Hoed, M., Khaw, K-T., Oskari Kilpeläinen, T., Wareham, N., Edwards, T. L., Hallmans, G., Varga, T. V., Kardia, S. L. R., Smith, J. A., Zhao, W. & 31 others, , 17 Mar 2015, In: Human Molecular Genetics. 24, 2, p. 3582–3594 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of PTBP1 rs11085226 on glucose-stimulated insulin release in adult Danes
Hansen, T. H., drb459, drb459, Jørgensen, T., Jørgensen, M. E., Lauritzen, T., Brandslund, I., Christensen, C., Pedersen, Oluf Borbye, Hansen, Torben & Gjesing, A. M. P., 20 Mar 2015, In: BMC Medical Genetics. 16, p. 1-9 9 p., 17.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
No association of maternal gestational weight gain with offspring blood pressure and hypertension at age 18 years in male sibling-pairs: a prospective register-based cohort study
Scheers Andersson, E., Tynelius, P., Nohr, E. A., Sørensen, Thorkild I.A. & Rasmussen, F., 20 Mar 2015, In: PLOS ONE. 10, 3, p. 1-12 12 p., e0121202.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
iRNA-seq: computational method for genome-wide assessment of acute transcriptional regulation from total RNA-seq data
Madsen, J. G. S., Schmidt, S. F., Larsen, B. D., Loft, A., Nielsen, R. & Mandrup, S., 31 Mar 2015, In: Nucleic Acids Research. 43, 6, p. 1-9 9 p., e40.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Alterations in molecular muscle mass regulators after 8 days immobilizing Special Forces mission
Jespersen, J. G., Mikkelsen, U. R., Nedergaard, A., Thorlund, J. B., Schjerling, Peter, Suetta, Charlotte, Christensen, P. A. & Aagaard, P., Apr 2015, In: Scandinavian Journal of Medicine & Science in Sports. 25, 2, p. 175-183 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Critical role of somatostatin receptor 2 in the vulnerability of the central noradrenergic system: new aspects on Alzheimer's disease
Ádori, C., Glück, L., Barde, S., Yoshitake, T., Kovacs, G. G., Mulder, J., Maglóczky, Z., Havas, L., Bölcskei, K., Mitsios, N., Uhlén, M., Szolcsányi, J., Kehr, J., Rönnbäck, A., Schwartz, Thue W., Rehfeld, Jens Frederik, Harkany, T., Palkovits, M., Schulz, S. & Hökfelt, T., Apr 2015, In: Acta Neuropathologica. 129, 4, p. 541-63 23 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dairy proteins, dairy lipids, and postprandial lipemia in persons with abdominal obesity (DairyHealth): a 12-wk, randomized, parallel-controlled, double-blinded, diet intervention study
Bohl, M., Bjørnshave, A., Rasmussen, K. V., Schioldan, A. G., Amer, B., Larsen, M. K., Dalsgaard, T. K., Holst, Jens Juul, Herrmann, A., O'Neill, S., O'Driscoll, L., Afman, L., Jensen, E., Christensen, M. M., Gregersen, S. & Hermansen, K., Apr 2015, In: The American Journal of Clinical Nutrition. 101, 4, p. 870-8 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Deep proteomics of mouse skeletal muscle enables quantitation of protein isoforms, metabolic pathways and transcription factors
Deshmukh, Atul Shahaji, Murgia, M., Nagaraja, N., Treebak, Jonas Thue, Cox, J. & Mann, Matthias, Apr 2015, In: Molecular and Cellular Proteomics. 14, 4, p. 841-853Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Discovery of coding genetic variants influencing diabetes-related serum biomarkers and their impact on risk of type 2 diabetes
Ahluwalia, Tarun Veer Singh, Allin, K. H., Sandholt, C. H., Sparsø, T. H., Jørgensen, M. E., Rowe, M., Christensen, C., Brandslund, I., Lauritzen, T., Linneberg, Allan René, Husemoen, L., Jørgensen, T., Hansen, Torben, Grarup, N. & Pedersen, Oluf Borbye, Apr 2015, In: The Journal of clinical endocrinology and metabolism. 100, 4, p. E664-71Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Global Longitudinal Strain Is Not Impaired in Type 1 Diabetes Patients Without Albuminuria: The Thousand & 1 Study
Jensen, M. T., Sogaard, P., Andersen, H. U., Bech, J., Fritz Hansen, T., Biering-Sørensen, Tor, Jørgensen, P. G., Galatius, S., Madsen, J. K., Rossing, Peter & Jensen, J. S., Apr 2015, In: J A C C: Cardiovascular Imaging. 8, 4, p. 400-10 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G protein-coupled receptors
Hamann, J., Aust, G., Araç, D., Engel, F. B., Formstone, C., Fredriksson, R., Hall, R. A., Harty, B. L., Kirchhoff, C., Knapp, B., Krishnan, A., Liebscher, I., Lin, H-H., Martinelli, D. C., Monk, K. R., Cornelia Peeters, M., Piao, X., Prömel, S., Schöneberg, T., Schwartz, T. W. & 9 others, , Apr 2015, In: Pharmacological Reviews. 67, 2, p. 338-67 30 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Is the adiposity-associated FTO gene variant related to all-cause mortality independent of adiposity? Meta-analysis of data from 169,551 Caucasian adults
Zimmermann, E., Ängquist, L. H., Mirza, S. S., Zhao, J. H., Chasman, D. I., Fischer, K., Qi, Q., Smith, A. V., Thinggaard, M., Jarczok, M. N., Nalls, M. A., Trompet, S., Timpson, N. J., Schmidt, B., Jackson, A. U., Lyytikäinen, L. P., Verweij, N., Mueller-Nurasyid, M., Vikström, M., Marques-Vidal, P. & 31 others, , Apr 2015, In: Obesity Reviews. 16, 4, p. 327-40 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Maternal weight change from prepregnancy to 7 years postpartum: the influence of behavioral factors
Kirkegaard, H., Stovring, H., Rasmussen, K. M., Abrams, B., Sørensen, Thorkild I.A. & Nohr, E. A., Apr 2015, In: Obesity. 23, 4, p. 870-8 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Measurement of the incretin hormones: glucagon-like peptide-1 and glucose-dependent insulinotropic peptide
Kuhre, Rune Ehrenreich, Albrechtsen, Nicolai Jacob Wewer, Hartmann, Bolette, Deacon, Carolyn F. & Holst, Jens Juul, Apr 2015, In: Journal of Diabetes and its Complications. 29, 3, p. 445-450 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Patients with psoriasis are insulin resistant
Gyldenløve, M., Storgaard, H., Holst, Jens Juul, Vilsbøll, T., Knop, Filip Krag & Skov, Lone, Apr 2015, In: Journal of the American Academy of Dermatology. 72, 4, p. 599-605 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effects of TNF-α on GLP-1-stimulated plasma glucose kinetics
Lehrskov-Schmidt, L., Lehrskov-Schmidt, L., Nielsen, S. T., Holst, Jens Juul, Møller, K. & Solomon, T. P. J., Apr 2015, In: The Journal of clinical endocrinology and metabolism. 100, 4, p. E616-E622 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Expression of the short chain fatty acid receptor GPR41/FFAR3 in autonomic and somatic sensory ganglia
Nøhr, M. K., Egerod, Kristoffer Lihme, Christiansen, S. H., Gille, A., Offermanns, S., Schwartz, Thue W. & Møller, Morten, 2 Apr 2015, In: Neuroscience. 290, p. 126-37 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Central 5-HT Neurotransmission Modulates Weight Loss following Gastric Bypass Surgery in Obese Individuals
Haahr, M. E., Hansen, D. L., Fisher, P. M., Svarer, C., Stenbæk, D. S., Madsen, K., Madsen, J., Holst, Jens Juul, Baaré, W. F. C., Højgaard, Liselotte, Almdal, T. & Knudsen, G. M., 8 Apr 2015, In: The Journal of neuroscience : the official journal of the Society for Neuroscience. 35, 14, p. 5884-5889 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
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Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets
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The isoenzyme pattern of LDH does not play a physiological role; except perhaps during fast transitions in energy metabolism
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Determinants of plasma levels of proglucagon and the metabolic impact of glucagon receptor signalling: a UK Biobank study
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