- 2015
- Published
Oral microbiota in patients with atherosclerosis
Fåk, F., Tremaroli, V., Bergström, G. & Bäckhed, G. F., Dec 2015, In: Atherosclerosis. 243, 2, p. 573-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Recent Progress in the Understanding of Obesity: Contributions of Genome-Wide Association Studies
Lepola, Mette Andersen & Sandholt, C. H., Dec 2015, In: Current Obesity Reports. 4, 4, p. 401-10 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Role of PKCδ in Insulin Sensitivity and Skeletal Muscle Metabolism
Li, M., Vienberg, S. G., Bezy, O., O'Neill, B. T. & Kahn, C. R., Dec 2015, In: Diabetes. 64, 12, p. 4023-32 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sex Differences in the Association Between Birth Weight and Adult Type 2 Diabetes
Zimmermann, E., Gamborg, Michael Orland, Sørensen, Thorkild I.A. & Baker, J. L., Dec 2015, In: Diabetes. 64, 12, p. 4220-4225 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Smoking and diabetes risk: building a causal case with clinical implications
Sattar, N., Sørensen, Thorkild I.A., Taylor, A. E., Morris, R. & Munafò, M. R., Dec 2015, In: The Lancet Diabetes & Endocrinology. 3, 12, p. 918-20 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The adhesion G protein-coupled receptor G2 (ADGRG2/GPR64) constitutively activates SRE and NFκB and is involved in cell adhesion and migration
Cornelia Peeters, M., Fokkelman, M., Boogaard, B., Egerod, Kristoffer Lihme, van de Water, B., IJzerman, A. P. & Schwartz, Thue W., Dec 2015, In: Cellular Signalling. 27, 12, p. 2579-88 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Twelve-Week Treatment With Liraglutide as Add-on to Insulin in Normal-Weight Patients With Poorly Controlled Type 1 Diabetes: A Randomized, Placebo-Controlled, Double-Blind Parallel Study
Frandsen, C. S., Dejgaard, T. F., Holst, Jens Juul, Andersen, H. U., Thorsteinsson, B. & Madsbad, Sten, Dec 2015, In: Diabetes Care. 38, 12, p. 2250-7 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dietary Fiber-Induced Improvement in Glucose Metabolism Is Associated with Increased Abundance of Prevotella
Kovatcheva-Datchary, P., Nilsson, A., Akrami, R., Lee, Y. S., De Vadder, F., Arora, T., Hallen, A., Martens, E., Björck, I. & Bäckhed, G. F., 1 Dec 2015, In: Cell Metabolism. 22, 6, p. 971-82 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gene-based meta-analysis of genome-wide association studies implicates new loci involved in obesity
Hägg, S., Ganna, A., Van Der Laan, S. W., Esko, T., Pers, Tune H, Locke, A. E., Berndt, S. I., Justice, A. E., Kahali, B., Siemelink, M. A., Pasterkamp, G., Strachan, D. P., Speliotes, E. K., North, K. E., Loos, Ruth, Hirschhorn, J. N., Pawitan, Y., Ingelsson, E. & GIANT Consortium, G. C., 1 Dec 2015, In: Human Molecular Genetics. 24, 23, p. 6849-60 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
RNA-Seq and Mass-Spectrometry-Based Lipidomics Reveal Extensive Changes of Glycerolipid Pathways in Brown Adipose Tissue in Response to Cold
Marcher, A., Loft, A., Nielsen, R., Vihervaara, T., Madsen, J. G. S., Sysi-Aho, M., Ekroos, K. & Mandrup, S., 1 Dec 2015, In: Cell Reports. 13, 9, p. 2000-13 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Science AMA Series: We’re researchers at the NNF Center for Basic Metabolic Research, University of Copenhagen. We recently published a study showing that obesity may be inherited through epigenetic modifications in sperm. Ask us anything! Obesity and Bariatric Surgery Drive Epigenetic Variation of Spermatozoa in Humans
Donkin, I., Versteyhe, S., Ingerslev, L. R. & Barrès, Romain, 14 Dec 2015Research output: Other contribution › Net publication - Internet publication › Communication
- Published
Long-term risk of cardiovascular and cerebrovascular disease after removal of the colonic microbiota by colectomy: a cohort study based on the Danish National Patient Register from 1996 to 2014
Jensen, A. B., Ajslev, T. A., Brunak, Søren & Sørensen, Thorkild I.A., 15 Dec 2015, In: B M J Open. 5, 8 p., e008702.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Drug the Bug!
Jonsson, A. L. & Bäckhed, G. F., 17 Dec 2015, In: Cell. 163, 7, p. 1565-6 2 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- 2016
- Published
RAD51B in Familial Breast Cancer
Pelttari, L. M., Khan, S., Vuorela, M., Kiiski, J. I., Vilske, S., Nevanlinna, V., Ranta, S., Schleutker, J., Winqvist, R., Kallioniemi, A., Dörk, T., Bogdanova, N. V., Figueroa, J., Pharoah, P. D. P., Schmidt, M. K., Dunning, A. M., García-Closas, M., Bolla, M. K., Dennis, J., Michailidou, K. & 31 others, , 2016, In: PLOS ONE. 11, 5, 18 p., e0153788.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Systematic Comparison of Purification and Normalization Protocols for Quantitative MicroRNA Expressional Profiling in Insulin-Producing Cells
Vestergaard, A. L., Blankestijn, M., Stahl, J. L., Pallesen, E. M. H., Bang-Berthelsen, C. H., Pociot, Flemming, Novotny, G. W., Lundh, M. & Mandrup-Poulsen, Thomas, 2016, In: International Journal of Molecular Sciences (Online). 17, 6, 8 p., 896.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
A comprehensive compartmental model of blood glucose regulation for healthy and type 2 diabetic subjects
Vahidi, O., Kwok, K. E., Gopaluni, R. B. & Knop, Filip Krag, 2016, In: Medical & Biological Engineering & Computing. 54, 9, p. 1383-1398 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration
de Vries, P. S., Chasman, D. I., Sabater-Lleal, M., Chen, M-H., Huffman, J. E., Steri, M., Tang, W., Teumer, A., Marioni, R. E., Grossmann, V., Hottenga, J. J., Trompet, S., Müller-Nurasyid, M., Zhao, J. H., Brody, J. A., Kleber, M. E., Guo, X., Wang, J. J., Auer, P. L., Attia, J. R. & 111 others, , 2016, In: Human Molecular Genetics. 25, 2, p. 358-370 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Acute disruption of glucagon secretion or action does not improve glucose tolerance in an insulin-deficient mouse model of diabetes
Steenberg, V. R., Jensen, S. M., Pedersen, Jens, Madsen, A. N., Windeløv, Johanne Agerlin, Holst, Birgitte, Quistorff, B., Poulsen, Steen Seier & Holst, Jens Juul, 2016, In: Diabetologia. 59, 2, p. 363-370 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Alle mulige vilde ting: Et nedslag i ny materialitetsfilosofi
Bencard, Adam, 2016, In: Passepartout. 37, p. 35-49 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Alterations in fecal microbiota composition by probiotic supplementation in healthy adults: a systematic review of randomized controlled trials
Kristensen, N. B., Bryrup, T., Allin, K. H., Nielsen, T., Hansen, T. H. & Pedersen, Oluf Borbye, 2016, In: Genome Medicine. 8, 1, 11 p., 52.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Altered Methylation Profile of Lymphocytes Is Concordant with Perturbation of Lipids Metabolism and Inflammatory Response in Obesity
Jacobsen, M. J., Mentzel, Caroline M. Junker, Olesen, A. S., Huby, T., Jørgensen, Claus Bøttcher, Barrès, Romain, Fredholm, Merete & Simar, D., 2016, In: Journal of Diabetes Research. 2016, p. 1-11 8539057.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An Improved Method for High Quality Metagenomics DNA Extraction from Human and Environmental Samples
Bag, S., Saha, B., Mehta, O., Anbumani, D., Kumar, N., Dayal, M., Pant, A., Kumar, P., Saxena, S., Allin, K. H., Hansen, T., Arumugam, M., Vestergaard, H., Pedersen, O., Pereira, V., Abraham, P., Tripathi, R., Wadhwa, N., Bhatnagar, S., Prakash, V. G. & 7 others, , 2016, In: Scientific Reports. 6, 9 p., 26775.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association between Maternal Fish Consumption and Gestational Weight Gain: Influence of Molecular Genetic Predisposition to Obesity
Larsen, S. C., Ängquist, Lars, Laurin, C., Morgen, C. S., Jakobsen, M. U., Paternoster, L., Smith, G. D., Olsen, S. F., Sørensen, Thorkild I.A. & Nohr, E. A., 2016, In: PloS one. 11, 3, 16 p., e0150105.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation
Gusev, A., Shi, H., Kichaev, G., Pomerantz, M., Li, F., Long, H. W., Ingles, S. A., Kittles, R. A., Strom, S. S., Rybicki, B. A., Nemesure, B., Isaacs, W. B., Zheng, W., Pettaway, C. A., Yeboah, E. D., Tettey, Y., Biritwum, R. B., Adjei, A. A., Tay, E., Truelove, A. & 31 others, , 2016, In: Nature Communications. 7, p. 1-13 13 p., 10979.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Benefits and Harms of Sodium-Glucose Co-Transporter 2 Inhibitors in Patients with Type 2 Diabetes: A Systematic Review and Meta-Analysis
Storgaard, H., Gluud, Lise Lotte, Bennett, C., Grøndahl, M. F., Christensen, Mikkel Bring, Knop, Filip Krag & Vilsbøll, Tina, 2016, In: PLOS ONE. 11, 11, 23 p., e0166125.Research output: Contribution to journal › Review › Research › peer-review
- Published
Blood-based biomarkers of age-associated epigenetic changes in human islets associate with insulin secretion and diabetes
Bacos, K., Gillberg, L., Volkov, P., Olsson, A. H., Hansen, Torben, Pedersen, Oluf Borbye, Gjesing, A. M. P., Eiberg, Hans Rudolf Lytchoff, Tuomi, T., Almgren, P., Groop, L., Eliasson, L., Vaag, Allan, Dayeh, T. & Ling, C., 2016, In: Nature Communications. 7, 13 p., 11089.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Body mass index at school age and hospital admissions for asthma in early adulthood: A prospective study of 321,830 children
Ulrik, Charlotte Suppli, Lophaven, S. N., Andersen, Zorana Jovanovic, Sørensen, Thorkild I.A. & Baker, J. L., 2016.Research output: Contribution to conference › Paper › Research › peer-review
- Published
Childhood body mass index and height and risk of histologic subtypes of endometrial cancer
Aarestrup, J., Gamborg, Michael Orland, Ulrich, L. G., Sørensen, Thorkild I.A. & Baker, J. L., 2016, In: International Journal of Obesity. 40, p. 1096-1102 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Colonic transit time is related to bacterial metabolism and mucosal turnover in the gut
Roager, Henrik Munch, Hansen, L. B. S., Bahl, M. I., Frandsen, H. L., Carvalho, V., Gøbel, R. J., Dalgaard, M. D., Plichta, D. R., Sparholt, M. H., drb459, drb459, Hansen, Torben, Sicheritz-Ponten, T., Nielsen, H. B., Pedersen, Oluf Borbye, Lauritzen, Lotte, Kristensen, M. B., Gupta, R. & Licht, T. R., 2016, In: Nature Microbiology. 1, 9, 9 p., 16093.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparative review of dipeptidyl peptidase-4 inhibitors and sulphonylureas.
Deacon, Carolyn F. & Lebovitz, H., 2016, In: Diabetes, Obesity and Metabolism. 18, 4, p. 333-347 15 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Comparison of sensory-specific satiety between normal weight and overweight children
Rischel, H. E., Nielsen, L. A., Gamborg, Michael Orland, Møller, P. & Holm, Jens-Christian, 2016, In: Appetite. 107, p. 486-493 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Contribution of heritability and epigenetic factors to skeletal muscle mass variation in United Kingdom twins
Livshits, G., Gao, F., Malkin, I., Needhamsen, M., Xia, Y., Yuan, W., Bell, C. G., Ward, K., Liu, Y., Wang, J., Bell, J. T. & Spector, T. D., 2016, In: Journal of Clinical Endocrinology and Metabolism. 101, 6, p. 2450-2459 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
DNA methylation and gene expression of HIF3A: cross-tissue validation and associations with BMI and insulin resistance
Main, A. M., Gillberg, L., Jacobsen, A. L., Nilsson, E., Gjesing, A. M. P., Hansen, Torben, Pedersen, Oluf Borbye, Ribel-Madsen, R. & Vaag, Allan, 2016, In: Clinical Epigenetics. 8, p. 1-7 7 p., 89.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
DPP-4 inhibitors
Deacon, Carolyn F., 2016, Handbook of incretin therapies in type 2 diabetes. Gough, S. (ed.). Switzerland: Springer, p. 45-60Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication
- Published
Dating of Pregnancy in First versus Second Trimester in Relation to Post-Term Birth Rate: A Cohort Study
Thagaard, I. N., Krebs, Lone, Lausten-Thomsen, U., Olesen-Larsen, S., Holm, Jens-Christian, Christiansen, M. & Larsen, T., 2016, In: PloS one. 11, 1, 9 p., e0147109.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dietary fat drives whole-body insulin resistance and promotes intestinal inflammation independent of body weight gain
Jensen, Benjamin Anderschou Holbech, Nielsen, Thomas Svava, Fritzen, Andreas Mæchel, Holm, J. B., Fjære, E., Serup, A. K. L., Borkowski, K., Risis, S., Pærregaard, S. I., Søgaard, I., Poupeau, A. A. G., Poulsen, M., Ma, Tao, Sina, C., Kiens, Bente, Madsen, L., Kristiansen, Karsten & Treebak, Jonas Thue, 2016, In: Metabolism. 65, 12, p. 1706-1719 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dynamics of glucagon secretion in mice and rats revealed using a validated sandwich ELISA for small sample volumes.
Albrechtsen, Nicolai Jacob Wewer, Kuhre, Rune Ehrenreich, Windeløv, Johanne Agerlin, Ørgaard, A., Deacon, Carolyn F., Kissow, Hannelouise, Hartmann, Bolette & Holst, Jens Juul, 2016, In: American Journal of Physiology: Endocrinology and Metabolism. 311, 2, p. E302-E309 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of copper nanoparticles and copper sulphate on metabolic rate and development of broiler embryos
Scott, A. T. A., Vadalasetty, K. P., Sawosz, E., Lukasiewicz, M., Vadalasetty, R. K. P., Jaworski, S. & Chwalibog, André, 2016, In: Animal Feed Science and Technology. 220, p. 151-158 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of mineralocorticoid receptor antagonists on proteinuria and progression of chronic kidney disease: a systematic review and meta-analysis
Currie, G., Taylor, A. H. M., Fujita, T., Ohtsu, H., Lindhardt, M., Rossing, Peter, Boesby, L., Edwards, N. C., Ferro, C. J., Townend, J. N., van den Meiracker, A. H., Saklayen, M. G., Oveisi, S., Jardine, A. G., Delles, C., Preiss, D. J. & Mark, P. B., 2016, In: B M C Nephrology. 17, p. 1-14 14 p., 127.Research output: Contribution to journal › Review › Research › peer-review
- Published
Effects of RYGB on energy expenditure, appetite and glycemic control: a randomized controlled clinical trial
Schmidt, J. B., Pedersen, S. D., Gregersen, N. T., Vestergaard Nielsen, L., Nielsen, M. S., Ritz, C., Madsbad, Sten, Worm, Dorte, Hansen, D. L., Clausen, T. R., Rehfeld, Jens Frederik, Astrup, A., Holst, Jens Juul & Sjödin, Anders Mikael, 2016, In: International Journal of Obesity. 40, 2, p. 281-290 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of a Family-Based Childhood Obesity Treatment Program on Parental Weight Status
Trier, C., Dahl, M., Stjernholm, T., Nielsen, T. R. H., Bøjsøe, C., Fonvig, C. E., Pedersen, Oluf Borbye, Hansen, Torben & Holm, Jens-Christian, 2016, In: P L o S One. 11, 8, p. 1-11 11 p., e0161921.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of biphasic, basal-bolus or basal insulin analogue treatments on carotid intima-media thickness in patients with type 2 diabetes mellitus: the randomised Copenhagen Insulin and Metformin Therapy (CIMT) trial
Lundby-Christensen, L., Vaag, A., Tarnow, L., Almdal, T. P., Lund, S. S., Wetterslev, J., Gluud, C., Boesgaard, T. W., Wiinberg, N., Perrild, H., Krarup, T., Snorgaard, O., Gade-Rasmussen, B., Thorsteinsson, B., Røder, M., Mathiesen, E. R., Jensen, T., Vestergaard, H., Hedetoft, C., Breum, L. & 6 others, , 2016, In: B M J Open. 6, 2, e008377.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Epigenetic programming of adipose-derived stem cells in low birthweight individuals
Broholm, C., Olsson, A. H., Perfilyev, A., Hansen, N. S., Schrölkamp, M., Strasko, K. S., Schéele, Camilla Charlotte Nielsen, Ribel-Madsen, R., Mortensen, B., Jørgensen, S. W., Ling, C. & Vaag, Allan, 2016, In: Diabetologia. 59, 12, p. 2664-2673 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evaluation of type 2 diabetes genetic risk variants in Chinese adults: findings from 93,000 individuals from the China Kadoorie Biobank
Gan, W., Walters, R. G., Holmes, M. V., Bragg, F., Millwood, I. Y., Banasik, Karina, Chen, Y., Du, H., Iona, A., Mahajan, A., Yang, L., Bian, Z., Guo, Y., Clarke, R. J., Li, L., McCarthy, M. I., Chen, Z. & China Kadoorie Biobank Collaborative Group, C. K. B. C. G., 2016, In: Diabetologia. 59, 7, p. 1446-1457 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evidence for L1-associated DNA rearrangements and negligible L1 retrotransposition in glioblastoma multiforme
Carreira, P. E., Ewing, A. D., Li, G., Schauer, S. N., Upton, K. R., Fagg, A. C., Morell, S., Kindlova, M., Gerdes, P., Richardson, S. R., Li, B., Gerhardt, D. J., Wang, J., Brennan, P. M. & Faulkner, G. J., 2016, In: Mobile D N A. 7, 14 p., 21.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
FFAR4 (GPR120) signaling is not required for anti-inflammatory and insulin-sensitizing effects of omega-3 fatty acids
Pærregaard, S. I., Andersen, M. A., Serup, A. K. L., Ma, Tao, Kiens, Bente, Madsen, L., Kristiansen, Karsten & Jensen, Benjamin Anderschou Holbech, 2016, In: Mediators of Inflammation. 2016, 12 p., 1536047.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
FTO genotype and weight loss: systematic review and meta-analysis of 9563 individual participant data from eight randomised controlled trials
Livingstone, K. M., Celis-Morales, C., Papandonatos, G. D., Erar, B., Florez, J. C., Jablonski, K. A., Razquin, C., Marti, A., Heianza, Y., Huang, T., Sacks, F. M., Svendstrup, M., Sui, X., Church, T. S., Jääskeläinen, T., Lindström, J., Tuomilehto, J., Uusitupa, M., Rankinen, T., Saris, W. H. M. & 12 others, , 2016, In: B M J. 354, 11 p., i4707.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP1- and GIP-producing cells rarely overlap and differ by bombesin receptor-2 expression and responsiveness
Svendsen, B., Pais, R., Engelstoft, M. S., Milev, N. B., Richards, P., Christiansen, Charlotte Bayer, Egerod, Kristoffer Lihme, Jensen, S. M., Habib, A. M., Gribble, F. M., Schwartz, Thue W., Reimann, F. & Holst, Jens Juul, 2016, In: Journal of Endocrinology. 228, 1, p. 39-48 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic Evidence for Causal Relationships Between Maternal Obesity-Related Traits and Birth Weight
Tyrrell, J., Richmond, R. C., Palmer, T. M., Feenstra, B., Rangarajan, J., Metrustry, S., Cavadino, A., Paternoster, L., Armstrong, L. L., De Silva, N. M. G., Wood, A. R., Horikoshi, M., Geller, F., Myhre, R., Bradfield, J. P., Kreiner-Møller, E., Huikari, V., Painter, J. N., Hottenga, J. J., Allard, C. & 31 others, , 2016, In: J A M A: The Journal of the American Medical Association. 315, 11, p. 1129-40 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic investigations of sudden unexpected deaths in infancy using next-generation sequencing of 100 genes associated with cardiac diseases
Hertz, C. L., Christiansen, S. L., Larsen, M. K., Dahl, M., Ferrero-Miliani, L., Weeke, P. E., Pedersen, Oluf Borbye, Hansen, Torben, Grarup, N., Ottesen, G. L., Frank-Hansen, R., Banner, Jytte & Morling, Niels, 2016, In: European Journal of Human Genetics. 24, p. 817–822Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetics of Type 2 diabetes: the power of isolated populations
Lepola, Mette Andersen, Pedersen, C. T., Moltke, Ida, Hansen, Torben, Albrechtsen, Anders & Grarup, N., 2016, In: Current Diabetes Reports. 16, 7, 9 p., 65.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index
Felix, J. F., Bradfield, J. P., Monnereau, C., van der Valk, R. J. P., Stergiakouli, E., Chesi, A., Gaillard, R., Feenstra, B., Thiering, E., Kreiner-Møller, E., Mahajan, A., Pitkänen, N., Joro, R., Cavadino, A., Huikari, V., Franks, S., Groen-Blokhuis, M. M., Cousminer, D. L., Marsh, J. A., Lehtimäki, T. & 31 others, , 2016, In: Human Molecular Genetics. 25, 2, p. 389-403Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide association studies (GWAS) of adiposity
Kilpeläinen, Tuomas O. & Ingelsson, E., 2016, The genetics of type 2 diabetes and related traits: Biology, physiology and translation. Florez, J. C. (ed.). 1 ed. Switzerland: Springer, p. 91-109Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Genome-wide association studies and resting heart rate
Kilpeläinen, Tuomas O., 2016, In: Journal of Electrocardiology. 49, 6, p. 860-863 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes
Imamura, M., Takahashi, A., Yamauchi, T., Hara, K., Yasuda, K., Grarup, N., Zhao, W., Wang, X., Huerta-Chagoya, A., Hu, C., Moon, S., Long, J., Kwak, S. H., Rasheed, A., Saxena, R., Ma, R. C. W., Okada, Y., Iwata, M., Hosoe, J., Shojima, N. & 43 others, , 2016, In: Nature Communications. 7, 12 p., 10531.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels
Kilpeläinen, T. O., Carli, J. F. M., Skowronski, A. A., Sun, Q., Kriebel, J., Feitosa, M. F., Hedman, Å. K., Drong, A. W., Hayes, J. E., Zhao, J., Pers, T. H., Schick, U., Grarup, N., Kutalik, Z., Trompet, S., Mangino, M., Kristiansson, K., Beekman, M., Lyytikäinen, L-P., Eriksson, J. & 157 others, , 2016, In: Nature Communications. 7, 14 p., 10494.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-1 receptor signaling in acinar cells causes growth dependent release of pancreatic enzymes
Albrechtsen, Nicolai Jacob Wewer, Albrechtsen, Reidar, Bremholm, L., Svendsen, B., Kuhre, Rune Ehrenreich, Poulsen, Steen Seier, Christiansen, Charlotte Bayer, Jensen, E. P., Janus, C., Hilsted, Linda, Deacon, Carolyn F., Hartmann, Bolette & Holst, Jens Juul, 2016, In: Cell Reports. 17, 11, p. 2845-2856 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gut hormones and gastric bypass
Holst, Jens Juul, 2016, In: Cardiovascular Endocrinology. 5, 3, p. 69-74 6 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
High BMI And Risk Of Exacerbations And Pneumonias In Individuals With COPD: Observational And Genetic Risk Estimates From The Copenhagen General Population Study
Colak, Y., Afzal, Shoaib, Lange, Peter & Nordestgaard, Børge, 2016, In: American Journal of Respiratory and Critical Care Medicine. 193, 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Human gut microbes impact host serum metabolome and insulin sensitivity
Pedersen, H. K., Gudmundsdottir, V., Nielsen, H. B., Hyotylainen, T., Nielsen, T., Jensen, B. A. H., Forslund, K., Hildebrand, F., Prifti, E., Falony, G., Le Chatelier, E., Levenez, F., Doré, J., Mattila, I., Plichta, D. R., Pöhö, P., Hellgren, L. I., Arumugam, M., Sunagawa, S., Vieira-Silva, S. & 14 others, , 2016, In: Nature. 535, 7612, p. 376-381 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer
Couch, F. J., Kuchenbaecker, K. B., Michailidou, K., Mendoza-Fandino, G. A., Nord, S., Lilyquist, J., Olswold, C., Hallberg, E., Agata, S., Ahsan, H., Aittomäki, K., Ambrosone, C. B., Andrulis, I. L., Anton-Culver, H., Arndt, V., Arun, B. K., Arver, B., Barile, M., Barkardottir, R. B., Barrowdale, D. & 229 others, , 2016, In: Nature Communications. 7, p. 1-13 13 p., 11375.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of novel genetic determinants of erythrocyte membrane fatty acid composition among Greenlanders
Lepola, Mette Andersen, Jørsboe, E., Sandholt, C. H., Grarup, N., Jørgensen, M. E., Færgeman, N. J., Bjerregaard, P., Pedersen, Oluf Borbye, Moltke, Ida, Hansen, Torben & Albrechtsen, Anders, 2016, In: P L o S Genetics. 12, 6, 19 p., e1006119.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of the TCF7L2 genotype on risk of hypoglycaemia and glucagon secretion during hypoglycaemia
Kristensen, P. L., Pedersen-Bjergaard, Ulrik, Due-Andersen, R., Høi-Hansen, T., Grimmeshave, L., Lyssenko, V., Groop, L., Holst, Jens Juul, Vaag, Allan & Thorsteinsson, B., 2016, In: Endocrine Connections. 5, 6, p. 53-60 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Important nuances on leucine and adipose browning
Lund, Jens, 2016, In: Trends in Pharmacological Sciences. 37, 9, p. 730-731 2 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
In Silico Investigation of the Neurotensin Receptor 1 Binding Site: Overlapping Binding Modes for Small Molecule Antagonists and the Endogenous Peptide Agonist
Lückmann, Michael, Holst, Birgitte, Schwartz, Thue W. & Frimurer, Thomas Michael, 2016, In: Molecular Informatics. 35, p. 19-24 6 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Inability of Some Commercial Assays to Measure Suppression of Glucagon Secretion
Albrechtsen, Nicolai Jacob Wewer, Veedfald, Simon, Plamboeck, A., Deacon, Carolyn F., Hartmann, Bolette, Knop, Filip Krag, Vilsbøll, Tina & Holst, Jens Juul, 2016, In: Journal of Diabetes Research. 2016, 5 p., 8352957.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Incretin hormones as a target for therapy
Holst, Jens Juul, 2016, Handbook of Incretin-based Therapies in Type 2 Diabetes. Gough, S. (ed.). Springer, p. 11-30Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication
- Published
Interactions between genetic variants associated with adiposity traits and soft drinks in relation to longitudinal changes in body weight and waist circumference
Olsen, N. J., Ängquist, Lars, Larsen, S. C., Linneberg, Allan René, Skaaby, T., Husemoen, L. L. N., Toft, Ulla Marie Nørgaard, Tjønneland, A., Halkjær, J., Hansen, Torben, Pedersen, Oluf Borbye, Overvad, K., Ahluwalia, T. S., Sørensen, Thorkild I.A. & Heitmann, Berit, 2016, In: American Journal of Clinical Nutrition. 104, 3, p. 816-826 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Maternal-fetal hepatic and placental metabolome profiles are associated with reduced fetal growth in a rat model of maternal obesity
Mumme, K., Gray, C., Reynolds, C. M., Vickers, M. H., Harrison, C. J., Stanley, J. L., Ruggiero, K., Villas-Bôas, S. G., Baker, P. N. & Sulek, K., 2016, In: Metabolomics. 12, 5, 10 p., 83.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Metformin versus placebo in combination with insulin analogues in patients with type 2 diabetes mellitus: the randomised, blinded Copenhagen Insulin and Metformin Therapy (CIMT) trial
Lundby-Christensen, L., Tarnow, L., Boesgaard, T. W., Lund, S. S., Wiinberg, N., Perrild, H., Krarup, T., Snorgaard, O., Gade-Rasmussen, B., Thorsteinsson, B., Røder, M., Mathiesen, E. R., Jensen, T., Vestergaard, H., Hedetoft, C., Breum, L., Duun, E., Sneppen, S. B., Pedersen, O., Hemmingsen, B. & 6 others, , 2016, In: B M J Open. 6, 2, e008376.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Minor Contribution of Endogenous GLP-1 and GLP-2 to Postprandial Lipemia in Obese Men
Matikainen, N., Björnson, E., Söderlund, S., Borén, C., Eliasson, B., Pietiläinen, K. H., Bogl, L. H., Hakkarainen, A., Lundbom, N., Rivellese, A., Riccardi, G., Després, J., Alméras, N., Holst, Jens Juul, Deacon, Carolyn F., Borén, J. & Taskinen, M., 2016, In: PLOS ONE. 11, 1, p. 1-15 15 p., e0145890.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Morbidity, Mortality And Lung Function In 14 Extracellular Superoxide Dismutase R213g Homozygotes Among 95,873 Individuals From The General Population
Kobylecki, C. J., Afzal, Shoaib & Nordestgaard, Børge, 2016, In: American Journal of Respiratory and Critical Care Medicine. 193, 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Multi-technique approach for qualitative and quantitative characterization of furazidin degradation kinetics under alkaline conditions
Bērziņš, Kārlis, Kons, A., Grante, I., Dzabijeva, D., Nakurte, I. & Actiņš, A., 2016, In: Journal of Pharmaceutical and Biomedical Analysis.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Muscle Contraction Induces Acute Hydroxymethylation of the Exercise-Responsive Gene Nr4a3
Pattamaprapanont, P., Garde, C., Fabre, O. & Barrès, Romain, 2016, In: Frontiers in Endocrinology. 7, 9 p., 165.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
No seasonality of birth in BMI at 7 years of age
Jensen, C. B., Sørensen, Thorkild I.A. & Heitmann, Berit, 2016, In: Early Human Development. 103, p. 129-131 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nonfasting Sample for the Determination of Routine Lipid Profile: Is It an Idea Whose Time Has Come?
Rifai, N., Young, I. S., Nordestgaard, Børge, Wierzbicki, A. S., Vesper, H., Mora, S., Stone, N. J., Genest, J. & Miller, G., 2016, In: Clinical Chemistry. 62, 3, p. 428-35 8 p.Research output: Contribution to journal › Comment/debate › Research
- Published
Normal values of left ventricularmass and cardiac chamber volumes assessed by 320-detector computed tomography angiography in the Copenhagen General Population Study
Fuchs, A., Mejdahl, M. R., Kühl, J. T., Stisen, Z. R., Nilsson, E. J. P., Køber, Lars Valeur, Nordestgaard, Børge & Kofoed, Klaus Fuglsang, 2016, In: European Heart Journal Cardiovascular Imaging. 17, 9, p. 1009-1017 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Oral 2-oleyl glyceryl ether improves glucose tolerance in mice through the GPR119 receptor
Hassing, H. A., Engelstoft, M. S., Sichlau, R. M., Madsen, A. N., Rehfeld, Jens Frederik, Pedersen, Jens, Jones, R. M., Holst, Jens Juul, Schwartz, Thue W., Rosenkilde, Mette & Hansen, Harald S., 2016, In: BioFactors. 42, 6, p. 665-673Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Oral treatment with improves insulin sensitivity in mice
Udayappan, S., Manneras-Holm, L., Chaplin-Scott, A., Belzer, C., Herrema, H., Dallinga-Thie, G. M., Duncan, S. H., Stroes, E. S. G., Groen, A. K., Flint, H. J., Backhed, F., de Vos, W. M. & Nieuwdorp, M., 2016, In: npj Biofilms and Microbiomes. 2, 10 p., 16009.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pancreatic α-cell hyperplasia and hyperglucagonemia due to a mutation of the glucagon
Larger, E., Albrechtsen, Nicolai Jacob Wewer, Hansen, L. H., Gelling, R. W., Capeau, J., Deacon, Carolyn F., Madsen, O. D., Yakushiji, F., Meyts, P. D., Holst, Jens Juul & Nishimura, E., 2016, In: Endocrinology, Diabetes & Metabolism Case Reports. 2016, 6 p., EDM160081.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Peptide production and secretion in GLUTag, NCI-H716 and STC-1 cells: a comparison to native L-cells.
Kuhre, Rune Ehrenreich, Albrechtsen, Nicolai Jacob Wewer, Deacon, Carolyn F., Balk-Møller, E., Rehfeld, Jens Frederik, Relman, F., Gribble, F. M. & Holst, Jens Juul, 2016, In: Journal of Molecular Endocrinology. 56, p. 201-211Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Physiology insights
Watanabe, R. M. & Hansen, Torben, 2016, The Genetics of Type 2 Diabetes and Related Traits: Biology, Physiology and Translation. Springer, p. 207-221 15 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Plasma alkylresorcinols reflect gluten intake and distinguish between gluten-rich and gluten-poor diets in a population at risk of metabolic syndrome
Lind, M. V., Madsen, M. L., Rumessen, J. J., drb459, drb459, Gøbel, R. J., Hansen, Torben, Lauritzen, Lotte, Pedersen, Oluf Borbye, Kristensen, M. B. & Ross, A. B., 2016, In: Journal of Nutrition. 146, 10, p. 1991-1998 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Proteomic prediction and Renin angiotensin aldosterone system Inhibition prevention Of early diabetic nephRopathy in TYpe 2 diabetic patients with normoalbuminuria (PRIORITY): essential study design and rationale of a randomised clinical multicentre trial
Lindhardt, M., Persson, F., Currie, G., Pontillo, C., Beige, J., Delles, C., von der Leyen, H., Mischak, H., Navis, G., Noutsou, M., Ortiz, A., Ruggenenti, P. L., Rychlik, I., Spasovski, G. & Rossing, Peter, 2016, In: B M J Open. 6, 3, 10 p., e010310.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Provision of amniotic fluid during parenteral nutrition increases weight gain with limited effects on gut structure, function, immunity, and microbiology in newborn preterm pigs
Østergaard, M. V., Shen, René Liang, Støy, A. C. F., Skovgaard, K., Krych, Ł., Leth, S. S., Nielsen, Dennis Sandris, Hartmann, Bolette, Bering, S. B., Schmidt, M. & Sangild, Per Torp, 2016, In: Journal of Parenteral and Enteral Nutrition. 40, 4, p. 552-566 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantification of the contribution of GLP-1 to mediating insulinotropic effects of DPP-4 inhibition with vildagliptin in healthy subjects and type 2-diabetic patients using exendin [9-39] as a GLP-1 receptor antagonist.
Nauck, M. A., Kind, J., Köthe, L. D., Holst, Jens Juul, Deacon, Carolyn F., Broschag, M., He, Y., Kjems, L. & Foley, J., 2016, In: Diabetes. 65, 8, p. 2440-2447 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
RFRP Neurons - The Doorway to Understanding Seasonal Reproduction in Mammals
Henningsen, J. B., Gauer, F. & Simonneaux, V., 2016, In: Frontiers in Endocrinology. 7, p. 36Research output: Contribution to journal › Review › Research › peer-review
- Published
Reference values for serum leptin in healthy non-obese children and adolescents
Lausten-Thomsen, U., Christiansen, M., Louise Hedley, P., Fonvig, C. E., Stjernholm, T., Pedersen, Oluf Borbye, Hansen, Torben & Holm, Jens-Christian, 2016, In: Scandinavian Journal of Clinical & Laboratory Investigation. 76, 7, p. 561-567 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Regulation of Lipolysis and Adipose Tissue Signaling during Acute Endotoxin-Induced Inflammation: A Human Randomized Crossover Trial
Rittig, N., Bach, E., Thomsen, H. H., Pedersen, S. B., Nielsen, Thomas Svava, Jørgensen, J. O., Jessen, N. & Møller, N., 2016, In: P L o S One. 11, 9, p. 1-13 13 p., e0162167.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Regulation of autophagy in human skeletal muscle: effects of exercise, exercise training and insulin stimulation
Fritzen, Andreas Mæchel, Madsen, A. L. B., Kleinert, Maximilian, Treebak, Jonas Thue, Lundsgaard, Anne-Marie, Jensen, Thomas Elbenhardt, Richter, Erik A., Wojtaszewski, Jørgen F P, Kiens, Bente & Frøsig, C., 2016, In: Journal of Physiology. 594, 3, p. 745-761 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Regulation of body fat mass by the gut microbiota: Possible mediation by the brain
Schéle, E., Grahnemo, L., Anesten, F., Hallén, A., Bäckhed, G. F. & Jansson, J., 2016, In: Peptides. 77, p. 54-9 6 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Renin angiotensin system blockade reduces urinary levels of soluble urokinase plasminogen activator receptor (suPAR) in patients with type 2 diabetes
Persson, F., Theilade, S., Eugen-Olsen, J., Rossing, Peter & Parving, H., 2016, In: Journal of Diabetes and its Complications. 30, 8, p. 1440-1442 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Risk stratification by endocrinologists of patients with type 2 diabetes in a Danish specialised outpatient clinic: a cross-sectional study
Munch, L., Arreskov, Anne Beiter, Sperling, M., Overgaard, D., Knop, Filip Krag, Vilsbøll, Tina & Røder, M. E., 2016, In: BMC Health Services Research. 16, 10 p., 124.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Role of AMP-activated protein kinase for regulating post-exercise insulin sensitivity
Kjøbsted, Rasmus, Wojtaszewski, Jørgen F P & Treebak, Jonas Thue, 2016, AMP-activated Protein Kinase. Cordero, M. D. & Viollet, B. (eds.). Springer, p. 81-126 46 p. (E X S, Vol. 107).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Roux-en-Y gastric bypass surgery of morbidly obese patients induces swift and persistent changes of the individual gut microbiota
Palleja, A., Kashani, A., Allin, K. H., Nielsen, T., Zhang, C., Li, Y., Brach, Thorsten, Liang, S., Feng, Q., Jørgensen, N. B., Bojsen-Møller, K. N., Dirksen, C., Burgdorf, Kristoffer Sølvsten, Holst, Jens Juul, Madsbad, Sten, Wang, J., Pedersen, Oluf Borbye, Hansen, Torben & Arumugam, Mani, 2016, In: Genome Medicine. 8, 13 p., 67.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sampling Random Bioinformatics Puzzles using Adaptive Probability Distributions
Have, C. T., Appel, E. V., Bork-Jensen, J. & Lassen, O. T., 2016, In: CEUR Workshop Proceedings. 1661, p. 39-45 7 p.Research output: Contribution to journal › Conference article › Research › peer-review
- Published
Serum lipase activity and concentration during intravenous infusions of GLP-1 and PYY3-36 and after ad libitum meal ingestion in overweight men
Schmidt, J. B., Sjödin, Anders Mikael, Stevner, L. S., Ritz, C., Michaelsen, N. B., Thomsen, A. B., Holst, Jens Juul & Astrup, A., 2016, In: Physiological Reports. 4, 18, 7 p., e12980.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Shared care management of patients with type 2 diabetes across the primary and secondary healthcare sectors: study protocol for a randomised controlled trial
Munch, L., Bennich, B., Arreskov, Anne Beiter, Overgaard, D., Konradsen, H., Knop, Filip Krag, Vilsbøll, Tina & Røder, M. E., 2016, In: Trials. 17, 10 p., 277.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Short-term effects of dietary advanced glycation end products in rats
Poulsen, M. W., Andersen, J. M., Hedegaard, R. S. V., Madsen, A. N., Krath, B. N., Monosik, R., Bak, M. J., Nielsen, J., Holst, Birgitte, Skibsted, Leif Horsfelt, Larsen, L. H. & Dragsted, Lars Ove, 2016, In: British Journal of Nutrition. 115, 4, p. 629-636 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The association between candidate migraine susceptibility loci and severe migraine phenotype in a clinical sample
Esserlind, A., Christensen, A. F., Steinberg, S., Grarup, N., Pedersen, Oluf Borbye, Hansen, Torben, Werge, Thomas, Hansen, T. F., Husemoen, L. L. N., Linneberg, Allan René, Budtz-Joergensen, Esben, Westergaard, M. L., Stefansson, H. & Olesen, Jes, 2016, In: Cephalalgia : an international journal of headache. 36, 7, p. 1-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
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Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets
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The isoenzyme pattern of LDH does not play a physiological role; except perhaps during fast transitions in energy metabolism
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Determinants of plasma levels of proglucagon and the metabolic impact of glucagon receptor signalling: a UK Biobank study
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The interplay between birth weight and obesity in determining childhood and adolescent cardiometabolic risk
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Targeting postsynaptic glutamate receptor scaffolding proteins PSD-95 and PICK1 for obesity treatment
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