- 2016
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The blunted effect of glucose-dependent insulinotropic polypeptide in subcutaneous abdominal adipose tissue in obese subjects is partly reversed by weight loss
Asmar, M., Arngrim, N., Simonsen, L., Asmar, A., Nordby, P., Holst, Jens Juul & Bülow, J., 2016, In: Nutrition and Diabetes. 6, 7 p., e208.Research output: Contribution to journal › Journal article › Research › peer-review
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The legacy of our ancestors' lifestyle
Barrès, Romain, 2016, In: Biochemist. 38, 2, p. 1-4 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Trends in adult body-mass index in 200 countries from 1975 to 2014: A pooled analysis of 1698 population-based measurement studies with 19.2 million participants
Damsgaard, Camilla Trab, Michaelsen, Kim F., Molbo, Drude, Mortensen, Erik Lykke, Sørensen, Thorkild I.A. & NCD Risk Factor Collaboration (NCD-RisC), N. R. F. C. (., 2016, In: The Lancet. 387, 10026, p. 1377-1396 20 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Twin's Birth-Order Differences in Height and Body Mass Index From Birth to Old Age: A Pooled Study of 26 Twin Cohorts Participating in the CODATwins Project
Yokoyama, Y., Jelenkovic, A., Sund, R., Sung, J., Hopper, J. L., Ooki, S., Heikkilä, K., Aaltonen, S., Tarnoki, A. D., Tarnoki, D. L., Willemsen, G., Bartels, M., van Beijsterveldt, T. C. E. M., Saudino, K. J., Cutler, T. L., Nelson, T. L., Whitfield, K. E., Wardle, J., Llewellyn, C. H., Fisher, A. & 48 others, , 2016, In: Twin Research and Human Genetics. 19, 2, p. 112-24 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
WITHDRAWN: Glucagon processing
Steiner, D. F., Albrechtsen, Nicolai Jacob Wewer, Rehfeld, Jens Frederik & Holst, Jens Juul, 2016, The Curated Reference Collection in Neuroscience and Biobehavioral Psychology. ElsevierResearch output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Adipokines in umbilical cord blood from children born large for gestational age
Lausten-Thomsen, U., Christiansen, M., Hedley, P. L., Holm, Jens-Christian & Schmiegelow, Kjeld, Jan 2016, In: Journal of Pediatric Endocrinology and Metabolism. 29, 1, p. 33-7 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Could gut microbiota protect against sclerosing cholangitis?
Marschall, H. & Bäckhed, G. F., Jan 2016, In: Hepatology. 63, 1, p. 26-7 2 p.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
Elevated Lipoprotein(a) Levels, LPA Risk Genotypes, and Increased Risk of Heart Failure in the General Population
Kamstrup, P. R. & Nordestgaard, Børge, Jan 2016, In: JACC. Heart failure. 4, 1, p. 78-87 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP-1 and Amylin in the Treatment of Obesity
Jorsal, T., Rungby, Jørgen, Knop, Filip Krag & Vilsbøll, Tina, Jan 2016, In: Current Diabetes Reports. 16, 1.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic associations with viral respiratory illnesses and asthma control in children
Loisel, D. A., Du, G., Ahluwalia, Tarun Veer Singh, Tisler, C. J., Evans, M. D., Myers, R. A., Gangnon, R. E., Kreiner-Møller, E., Bønnelykke, K., Bisgaard, H., Jackson, D. J., Lemanske, R. F., Nicolae, D. L. & Ober, C., Jan 2016, In: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. 46, 1, p. 112-24 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide association studies of body mass index
Kilpeläinen, Tuomas O., Jan 2016, Genome-wide association studies: From polymoprhism to personalized medicine. Appasani, K. (ed.). Cambridge, UK: Cambridge University Press, p. 69-78Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- Published
Multiplexed Quantification of Proglucagon-Derived Peptides by Immunoaffinity Enrichment and Tandem Mass Spectrometry after a Meal Tolerance Test
Lee, A. Y. H., Chappell, D. L., Bak, M. J., Judo, M., Liang, L., Churakova, T., Ayanoglu, G., Castro-Perez, J., Zhou, H., Previs, S., Souza, S. C., Lassman, M. E. & Laterza, O. F., Jan 2016, In: Clinical Chemistry. 62, 1, p. 227-35 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Neurotensin Is Co-Expressed, Co-Released And Acts Together With Glp-1 And Pyy In Enteroendocrine Control Of Metabolism
Grunddal, Kaare Villum, Ratner, C. F., Svendsen, B., Sommer, F., Engelstoft, M. S., Madsen, A. N., Pedersen, Jens, Nøhr, M. K., Egerod, Kristoffer Lihme, Nawrocki, A. R., Kowalski, T., Howard, A. D., Poulsen, Steen Seier, Offermanns, S., Bäckhed, G. F., Holst, Jens Juul, Holst, Birgitte & Schwartz, Thue W., Jan 2016, In: Endocrinology. 157, 1, p. 176-94 19 p., en20151600.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prenatal and early life influences on epigenetic age in children: A study of mother-offspring pairs from two cohort studies
Simpkin, A. J., Hemani, G., Suderman, M., Gaunt, T. R., Lyttleton, O., McArdle, W. L., Ring, S. M., Sharp, G. C., Tilling, K., Horvath, S., Kunze, S., Peters, A., Waldenberger, M., Ward-Caviness, C., Nohr, E. A., Sørensen, Thorkild I.A., Relton, C. L. & Smith, G. D., Jan 2016, In: Human Molecular Genetics. 25, 1, p. 191-201 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sex Hormones and Ischemic Stroke: A Prospective Cohort Study and Meta-Analyses
Holmegard, H. N., Nordestgaard, Børge, Jensen, G. B., Tybjærg-Hansen, Anne & Benn, Marianne, Jan 2016, In: The Journal of Clinical Endocrinology & Metabolism. 101, 1, p. 69-78 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Species-specific action of (Pro3)GIP - an efficacious agonist on human GIP receptor, but partial agonist and competitive antagonist on rat and mouse GIP receptors
wbf943, wbf943, Gasbjerg, Lærke Smidt, Svendsen, B., Christensen, M., Knop, Filip Krag, Hartmann, Bolette, Holst, Jens Juul & Rosenkilde, Mette, Jan 2016, In: British Journal of Pharmacology. 173, 1, p. 27-38 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Statins are independently associated with increased HbA1c in type 1 diabetes: The Thousand & 1 Study
Jensen, M. T., Andersen, H. U., Rossing, Peter & Jensen, J. S., Jan 2016, In: Diabetes Research and Clinical Practice. 111, p. 51–57Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cephalic phase secretion of insulin and other enteropancreatic hormones in humans
Veedfald, Simon, Plamboeck, A., Deacon, Carolyn F., Hartmann, Bolette, Knop, Filip Krag, Vilsbøll, Tina & Holst, Jens Juul, 1 Jan 2016, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 310, 1, p. G43-51Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The gut microbiota in type 2 diabetes
Nielsen, T., Allin, K. H. & Pedersen, Oluf Borbye, 1 Jan 2016, The Genetics of Type 2 Diabetes and Related Traits: Biology, Physiology and Translation. Springer, p. 275-293 19 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
The regulation of function, growth and survival of GLP-1-producing L-cells.
Kuhre, Rune Ehrenreich, Holst, Jens Juul & Kappe, C., 1 Jan 2016, In: Clinical Science. 130, 2, p. 79-91 13 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Effects of subcutaneous, low-dose glucagon on insulin-induced mild hypoglycaemia in patients with insulin pump treated type 1 diabetes
Ranjan, A., Schmidt, S., Madsbad, Sten, Holst, Jens Juul & Nørgaard, K., 7 Jan 2016, In: Diabetes, Obesity and Metabolism Online. 18, 4, p. 410-418Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comprehensive analysis of schizophrenia-associated loci highlights ion channel pathways and biologically plausible candidate causal genes
Pers, Tune H, Timshel, P., Ripke, S., Lent, S., Sullivan, P. F., O'Donovan, M. C., Franke, L., Hirschhorn, J. N. & Schizophrenia Working Group of the Psychiatric Genomics Consortium, S. W. G. O. T. P. G. C., 10 Jan 2016, In: Human Molecular Genetics. 25, 6, p. 1247-1254 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
TRAF2 mediates JNK and STAT3 activation in response to IL-1β and IFNγ and facilitates apoptotic death of insulin-producing β-cells
Prause, Michala Cecilie Burstein, Berchtold, L. A., Urizar, A. I., Trauelsen, Mette, Billestrup, Nils, Mandrup-Poulsen, Thomas & Størling, Joachim, 15 Jan 2016, In: Molecular and Cellular Endocrinology. 420, p. 24-36 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular characterization of irinotecan (SN-38) resistant human breast cancer cell lines
Jandu, H., Aluzaité, K., Fogh, L., Thrane, S. W., Noer, J. B., Proszek, J., Nguyen Do, K., Hansen, S. N., Damsgaard-Hansen, B., Nielsen, S. L., Stougaard, M., Knudsen, B. R., Moreira, J., Hamerlik, P., Gajjar, M., Smid, M., Martens, J., Foekens, J., Pommier, Y., Brünner, N. & 2 others, , 22 Jan 2016, In: B M C Cancer. 16, 13 p., 34.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Atrial Natriuretic Peptide in the high normal range is associated with lower prevalence of insulin resistance
Jujić, A., Nilsson, P. M., Persson, M., Holst, Jens Juul, Torekov, Signe Sørensen, Lyssenko, V., Groop, L., Melander, O. & Magnusson, M., 27 Jan 2016, In: The Journal of clinical endocrinology and metabolism. 101, 4, p. 1372-1380 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In vivo and in vitro degradation of peptide YY3-36 to inactive peptide YY3-34 in humans
Toräng, S., Bojsen-Møller, K. N., Svane, M. S., Hartmann, Bolette, Rosenkilde, Mette, Madsbad, Sten & Holst, Jens Juul, 27 Jan 2016, In: A J P: Regulatory, Integrative and Comparative Physiology (Online). 310, 1, p. R866-R874 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rapid gut growth but persistent delay in digestive function in the postnatal period of preterm pigs
Hansen, C. F., Thymann, Thomas, Andersen, A. D., Holst, Jens Juul, Hartmann, Bolette, Hilsted, Linda, Langhorn, L., Jelsing, J. & Sangild, Per Torp, 28 Jan 2016, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 310, 8, p. G550-560 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Are human endogenous retroviruses triggers of autoimmune diseases? Unveiling associations of three diseases and viral loci
Nexø, B. A., Villesen, P., Nissen, K. K., Lindegaard, H. M., Rossing, Peter, Petersen, T., Tarnow, L., Hansen, B., Lorenzen, T., Hørslev-Petersen, K., Jensen, S. B., Bahrami, S., Lajer, M., Schmidt, K. L. M., Parving, H., Junker, P. & Laska, M. J., Feb 2016, In: Immunologic Research. 64, 1, p. 55-63 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Early Weight Gain, Linear Growth, and Mid-Childhood Blood Pressure: A Prospective Study in Project Viva
Perng, W., Rifas-Shiman, S. L., Kramer, M. S., Haugaard, L. K., Oken, E., Gillman, M. W. & Belfort, M. B., Feb 2016, In: Hypertension. 67, 2, p. 301-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of Gastric Bypass and Gastric Banding on Bone Remodeling in Obese Patients with Type 2 Diabetes
Yu, E. W., Wewalka, M., Ding, S., Simonson, D. C., Foster, K., Holst, Jens Juul, Vernon, A., Goldfine, A. B. & Halperin, F., Feb 2016, In: Journal of Clinical Endocrinology and Metabolism. 101, 2, p. 714–722Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucose-dependent insulinotropic polypeptide (GIP) is associated with lower LDL but unhealthy fat distribution, independent of insulin: The ADDITION-PRO study
Møller, C. L., Vistisen, D., Færch, K., Johansen, N. B., Witte, D. R., Jonsson, Anna Elisabet, Pedersen, Oluf Borbye, Hansen, Torben, Lauritzen, T., Jørgensen, M. E., Torekov, Signe Sørensen & Holst, Jens Juul, Feb 2016, In: Journal of Clinical Endocrinology and Metabolism. 101, 2, p. 485– 493 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Intake of ruminant trans-fatty acids, assessed by diet history interview, and changes in measured body size, shape and composition
Hansen, C. P., Heitmann, Berit, Sørensen, Thorkild I.A., Overvad, K. & Jakobsen, M. U., Feb 2016, In: Public Health Nutrition. 19, 3, p. 494-502 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Jejunal feeding is followed by a greater rise in plasma cholecystokinin, peptide YY, glucagon-like peptide 1, and glucagon-like peptide 2 concentrations compared with gastric feeding in vivo in humans: a randomized trial
Luttikhold, J., van Norren, K., Rijna, H., Buijs, N., Ankersmit, M., Heijboer, A. C., Gootjes, J., Hartmann, Bolette, Holst, Jens Juul, van Loon, L. J. & van Leeuwen, P. A., Feb 2016, In: The American Journal of Clinical Nutrition. 103, 2, p. 435-43 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Late midlife C-reactive protein and interleukin-6 in middle aged danish men in relation to body size history within and across generations
Pedersen, J. L. M., Budtz-Joergensen, Esben, Mortensen, Erik Lykke, Bruunsgaard, H., Osler, Merete, Sørensen, Thorkild I.A., Rod, Naja Hulvej & Lund, Rikke, Feb 2016, In: Obesity. 24, 2, p. 461-468 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Safety and Efficacy of Liraglutide in Patients With Type 2 Diabetes and End-Stage Renal Disease: An Investigator-Initiated, Placebo-Controlled, Double-Blinded, Parallel Group, Randomized Trial
Idorn, T., Knop, Filip Krag, Jørgensen, M. B., Jensen, T., Resuli, M., Hansen, P. M., Christensen, Karl Bang, Holst, Jens Juul, Hornum, Mads & Feldt-Rasmussen, Bo, Feb 2016, In: Diabetes Care. 39, 2, p. 206-13 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Do glucagonomas always produce glucagon?
Albrechtsen, Nicolai Jacob Wewer, Challis, B., Damjanov, I. & Holst, Jens Juul, 1 Feb 2016, In: Bosnian Journal of Basic Medical Sciences. 16, 1, p. 1-7 7 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk
Lu, Y., Day, F. R., Gustafsson, S., Buchkovich, M. L., Na, J., Bataille, V., Cousminer, D. L., Dastani, Z., Drong, A. W., Esko, T., Evans, D. M., Falchi, M., Feitosa, M. F., Ferreira, T., Hedman, Å. K., Haring, R., Hysi, P. G., Iles, M. M., Justice, A. E., Kanoni, S. & 239 others, , 1 Feb 2016, In: Nature Communications. 7, p. 1-15 15 p., 10495.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The intestinal distribution pattern of appetite- and glucose regulatory peptides in mice, rats and pigs
Albrechtsen, Nicolai Jacob Wewer, Kuhre, Rune Ehrenreich, Toräng, S. & Holst, Jens Juul, 2 Feb 2016, In: BMC Research Notes. 9, 1, p. 1-6 6 p., 60.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Gut Microbiota Modulates Energy Metabolism in the Hibernating Brown Bear Ursus arctos
Sommer, F., Ståhlman, M., Ilkayeva, O., Arnemo, J. M., Kindberg, J., Josefsson, J., Newgard, C. B., Fröbert, O. & Bäckhed, G. F., 3 Feb 2016, In: Cell Reports. 14, 7, p. 1655-1661 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Proteomics of Skeletal Muscle: Focus on Insulin Resistance and Exercise Biology.
Deshmukh, Atul Shahaji, 4 Feb 2016, In: Proteomes.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
FGF21 Mediates Endocrine Control of Simple Sugar Intake and Sweet Taste Preference by the Liver
von Holstein-Rathlou, S., BonDurant, L. D., Peltekian, L., Naber, M. C., Yin, T. C., Claflin, K. E., Urizar, A. I., Madsen, A. N., Ratner, C., Holst, B., Karstoft, K., Vandenbeuch, A., Anderson, C. B., Cassell, M. D., Thompson, A. P., Solomon, T. P., Rahmouni, K., Kinnamon, S. C., Pieper, A. A., Gillum, M. P. & 1 others, , 9 Feb 2016, In: Cell Metabolism. 23, 2, p. 335-43 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Obesity and Bariatric Surgery Drive Epigenetic Variation of Spermatozoa in Humans
Donkin, I., Versteyhe, S., Ingerslev, L. R., Qian, K., Mechta, Mie, Nordkap, L., Mortensen, B., Appel, E. V. R., Jørgensen, N., Kristiansen, V. B., Hansen, Torben, Workman, C. T., Zierath, Juleen R & Barrès, Romain, 9 Feb 2016, In: Cell Metabolism. 23, 2, p. 369-78 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Major rapid weight loss induces changes in cardiac repolarization
Vedel-Larsen, E., Iepsen, E. P. W., Lundgren, J., Graff, C., Struijk, J. J., Hansen, Torben, Holst, Jens Juul, Madsbad, Sten, Torekov, Signe Sørensen & Kanters, Jørgen K., 10 Feb 2016, In: Journal of Electrocardiology. 49, 3, p. 467-472 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Asthma Associates With Human Abdominal Aortic Aneurysm and Rupture
Liu, C., Wemmelund, H., Wang, Y., Liao, M., Lindholt, J. S., Johnsen, S. P., drb459, drb459, Fernandes, C., Sukhova, G. K., Cheng, X., Zhang, J., Yang, C., Huang, X., Daugherty, A., Levy, B. D., Libby, P. & Shi, G., 11 Feb 2016, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 36, 3, p. 570-8 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Short-term effects of liraglutide on kidney function and vasoactive hormones in type 2 diabetes: a randomized clinical trial
Skov, J., Pedersen, M., Holst, Jens Juul, Madsen, B., Goetze, Jens P. , Rittig, S., Jonassen, Thomas, Frøkiær, J., Dejgaard, A. & Christiansen, J. S., 22 Feb 2016, In: Diabetes, Obesity and Metabolism Online. 18, 6, p. 581-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP-1 Restores Altered Insulin and Glucagon Secretion in Posttransplantation Diabetes
Halden, T. A. S., Egeland, E. J., Åsberg, A., Hartmann, A., Midtvedt, K., Khiabani, H. Z., Holst, Jens Juul, Knop, Filip Krag, Hornum, Mads, Feldt-Rasmussen, Bo & Jenssen, T., 23 Feb 2016, In: Diabetes Care. 39, p. 617-24Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mendelian randomisation study of the associations of vitamin B12 and folate genetic risk scores with blood pressure and fasting serum lipid levels in three Danish population-based studies
Husemoen, L. L. N., Skaaby, T., Thuesen, B. H., Grarup, N., Sandholt, C. H., Hansen, Torben, Pedersen, Oluf Borbye & Linneberg, Allan René, 24 Feb 2016, In: European Journal of Clinical Nutrition. 70, p. 613-619 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Altered DNA methylation of glycolytic and lipogenic genes in liver from obese and type 2 diabetic patients
Kirchner, H., Sinha, I., Gao, H., Ruby, M. A., Schönke, M., Lindvall, J. M., Barrès, Romain, Krook, A., Näslund, E., Dahlman-Wright, K. & Zierath, Juleen R, Mar 2016, In: Molecular Metabolism. 5, 3, p. 171-83 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Data on plasma levels of apolipoprotein E, correlations with lipids and lipoproteins stratified by APOE genotype, and risk of ischemic heart disease
Rasmussen, K. L., Tybjærg-Hansen, Anne, Nordestgaard, Børge & Frikke-Schmidt, Ruth, Mar 2016, In: Data in Brief. 6, p. 923-932 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Efficacy and safety of liraglutide for overweight adult patients with type 1 diabetes and insufficient glycaemic control (Lira-1): a randomised, double-blind, placebo-controlled trial
Dejgaard, T. F., Frandsen, C. S., Hansen, T. S., Almdal, Thomas Peter, Urhammer, Søren Asger, Pedersen-Bjergaard, Ulrik, Jensen, T., Jensen, Andreas Kryger, Holst, Jens Juul, Tarnow, L., Knop, Filip Krag, Madsbad, Sten & Andersen, H. U., Mar 2016, In: The Lancet Diabetes & Endocrinology. 4, 3, p. 221–232 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evidence of Extrapancreatic Glucagon Secretion in Man
Lund, Asger Bach, Bagger, J. I., Albrechtsen, Nicolai Jacob Wewer, Christensen, M., Grøndahl, M., Hartmann, Bolette, Mathiesen, Elisabeth, Hansen, C. P., Storkholm, J. H., van Hall, Gerrit, Rehfeld, Jens Frederik, Hornburg, D., Meissner, F., Mann, Matthias, Larsen, S., Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, Mar 2016, In: Diabetes. 65, 3, p. 585-597 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High-fat diet reprograms the epigenome of rat spermatozoa and transgenerationally affects metabolism of the offspring
de Castro Barbosa, T., Ingerslev, L. R., Alm, P. S., Versteyhe, S., Massart, J., Rasmussen, M., Donkin, I., Sjögren, R., Mudry, J. M., Vetterli, L., Gupta, S., Krook, A., Zierath, Juleen R & Barrès, Romain, Mar 2016, In: Molecular Metabolism. 5, 3, p. 184-97 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
IDegLira Improves Both Fasting and Postprandial Glucose Control as Demonstrated Using Continuous Glucose Monitoring and a Standardized Meal Test
Holst, Jens Juul, Buse, J. B., Rodbard, H. W., Linjawi, S., Woo, V. C., Boesgaard, T. W., Kvist, K. & Gough, S. C., Mar 2016, In: Journal of Diabetes Science and Technology. 10, 2, p. 389-97 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interaction between dietary lipids and gut microbiota regulates hepatic cholesterol metabolism
Caesar, R., Nygren, H., Orešič, M. & Bäckhed, G. F., Mar 2016, In: Journal of Lipid Research. 57, 3, p. 474-81 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
N- and C-terminally truncated forms of glucose-dependent insulinotropic polypeptide are high-affinity competitive antagonists of the human GIP receptor
Hansen, L. S., wbf943, wbf943, Christensen, M., Knop, Filip Krag, Hartmann, Bolette, Holst, Jens Juul & Rosenkilde, Mette, Mar 2016, In: British Journal of Pharmacology. 173, 5, p. 826-838 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pathogenic classification of LPL gene variants reported to be associated with LPL deficiency
Rodrigues, R., Artieda, M., Tejedor, D., Martínez, A., Konstantinova, P., Petry, H., Meyer, C., Corzo, D., Sundgreen, C., Klor, H. U., Gouni-Berthold, I., Westphal, S., Steinhagen-Thiessen, E., Julius, U., Winkler, K., Stroes, E., Vogt, A., Hardt, P., Prophet, H., Otte, B. & 3 others, , Mar 2016, In: Journal of Clinical Lipidology. 10, 2, p. 394-409 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Plasma levels of apolipoprotein E and risk of ischemic heart disease in the general population
Rasmussen, K. L., Tybjærg-Hansen, Anne, Nordestgaard, Børge & Frikke-Schmidt, Ruth, Mar 2016, In: Atherosclerosis. 246, p. 63-70 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Regulation of gut hormone secretion. Studies using isolated perfused intestines.
Svendsen, B. & Holst, Jens Juul, Mar 2016, In: Peptides. 77, p. 47-53 7 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Road Traffic and Railway Noise Exposures and Adiposity in Adults: A Cross-Sectional Analysis of the Danish Diet, Cancer, and Health Cohort
Christensen, J. S., Raaschou-Nielsen, O., Tjønneland, A., Overvad, K., Nordsborg, R. B., Ketzel, M., Sørensen, Thorkild I.A. & Sørensen, M., Mar 2016, In: Environmental Health Perspectives. 124, 3, p. 329-35 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Intake of Total and Subgroups of Fat Minimally Affect the Associations between Selected Single Nucleotide Polymorphisms in the PPARγ Pathway and Changes in Anthropometry among European Adults from Cohorts of the DiOGenes Study
Larsen, S. C., Ängquist, L., Østergaard, J. N., Ahluwalia, T. V. S., Vimaleswaran, K. S., Roswall, N., Mortensen, L. M., Nielsen, B. M., Tjønneland, A., Wareham, N. J., Palli, D., Masala, G., Saris, W. H., van der A, D. L., Boer, J. M., Feskens, E. J., Boeing, H., Jakobsen, M. U., Loos, R. J., Sørensen, T. I. & 1 others, , 1 Mar 2016, In: Journal of Nutrition. 146, 3, p. 603-611Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pleotropic effects of leptin to reverse insulin resistance and diabetic ketoacidosis
Perry, R. J., Petersen, K. F. & Shulman, G. I., 10 Mar 2016, In: Diabetologia. 59, 5, p. 933-937 5 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Sex-specific associations between birth weight and adult primary liver cancer in a large cohort of Danish children
Zimmermann, E., Berentzen, T. L., Gamborg, Michael Orland, Sørensen, Thorkild I.A. & Baker, J. L., 15 Mar 2016, In: International Journal of Cancer. 138, 6, p. 1410–1415 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Vaccine Targeting of Subdominant CD8+ T Cell Epitopes Increases the Breadth of the T Cell Response upon Viral Challenge, but May Impair Immediate Virus Control
Steffensen, Maria Abildgaard, Pedersen, L. H., Jahn, Marie Louise, Nielsen, K. N., Christensen, Jan Pravsgaard & Thomsen, Allan Randrup, 15 Mar 2016, In: Journal of Immunology. 196, 6, p. 2666-2676 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Insights into metabolic disease from studying genetics in isolated populations: stories from Greece to Greenland
Zeggini, E., Gloyn, A. L. & Hansen, Torben, 18 Mar 2016, In: Diabetologia. 59, 5, p. 938-941 4 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Know your neighbor: Microbiota and host epithelial cells interact locally to control intestinal function and physiology
Sommer, F. & Bäckhed, G. F., 18 Mar 2016, In: BioEssays. 38, 5, p. 455-464 10 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
The insulinotropic effect of exogenous GLP-1 is not affected by acute vagotomy in anaesthetized pigs
Veedfald, Simon, Hansen, M., Christensen, L. W., Larsen, S. A. H., Hjøllund, K. R., Plamboeck, A., Hartmann, Bolette, Deacon, Carolyn F. & Holst, Jens Juul, 30 Mar 2016, In: Experimental Physiology. 101, 7, p. 895-912 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Childhood body mass index and risk of schizophrenia in relation to childhood age, sex and age of first contact with schizophrenia
Sørensen, H. J., Gamborg, Michael Orland, Sørensen, Thorkild I.A., Baker, J. L. & Mortensen, Erik Lykke, Apr 2016, In: European Psychiatry. 34, p. 64-9 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Childhood height, adult height, and the risk of prostate cancer
Bjerregaard, L. G., Aarestrup, J., Gamborg, Michael Orland, Lange, Theis, Tjønneland, A. & Baker, J. L., Apr 2016, In: Cancer Causes & Control. 27, 4, p. 561-567 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparison of the long-term effects of LIiraglutide and Glimepiride monotherapy on bone mineral density in patients with type 2 diabetes
Gilbert, M. P., Marre, M., Holst, Jens Juul, Garber, A., Baeres, F. M. M., Thomsen, H. & Pratley, R. E., Apr 2016, In: Endocrine Practice. 22, 4, p. 406-411 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of glucagon-like peptide-1 on glucagon secretion in patients with non-alcoholic fatty liver disease
Junker, A. E., Gluud, Lise Lotte, van Hall, Gerrit, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, Apr 2016, In: Journal of Hepatology. 64, 4, p. 908–915Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Insulin-like peptide 5 is a microbially regulated peptide that promotes hepatic glucose production
Lee, Y. S., De Vadder, F., Tremaroli, V., Wichmann, A., Mithieux, G. & Bäckhed, G. F., Apr 2016, In: Molecular Metabolism. 5, 4, p. 263-70 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Levels of the inflammation marker YKL-40 in young adults exposed to intrauterine hyperglycemia
Kelstrup, L., Dejgaard, T. F., Clausen, Tine Dalsgaard, Mathiesen, Elisabeth, Hansen, Torben, drb459, drb459 & Damm, Peter, Apr 2016, In: Diabetes Research and Clinical Practice. 114, p. 50-4 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Liraglutide for treating type 1 diabetes
Dejgaard, T. F., Frandsen, C. S., Holst, Jens Juul & Madsbad, Sten, Apr 2016, In: Expert Opinion on Biological Therapy. 16, 4, p. 579-90 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Peptide YY3-36 and glucagon-like peptide-1 in functional dyspepsia. Secretion and role in symptom generation
Witte, A., Hilsted, Linda, Holst, Jens Juul & Schmidt, P. T., Apr 2016, In: Scandinavian Journal of Gastroenterology. 51, 4, p. 400-409 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prognostic impact of carboxylesterase 1 gene variants in patients with congestive heart failure treated with angiotensin-converting enzyme inhibitors
Nelveg-Kristensen, K. E., Madsen, M. B., Torp-Pedersen, C., Køber, Lars Valeur, Egfjord, Martin, Hansen, Torben, Pedersen, Oluf Borbye, Rasmussen, H. B. & Hansen, Peter Riis, Apr 2016, In: Pharmacogenetics and Genomics. 26, 4, p. 169–177 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pronounced expression of the lipolytic inhibitor G0/G1 Switch Gene 2 (G0S2) in adipose tissue from brown bears (Ursus arctos) prior to hibernation
Jessen, N., Nielsen, Thomas Svava, Vendelbo, M. H., Viggers, R., Støen, O., Evans, A. & Frøbert, O., Apr 2016, In: Physiological Reports. 4, 8, p. 1-7 7 p., e12781.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of endogenous GLP-1 and GIP on glucose tolerance after Roux-en-Y gastric bypass surgery
Svane, M. S., Bojsen-Moller, K. N., Nielsen, S., Jørgensen, N. B., Dirksen, C., Bendtsen, Flemming, Kristiansen, V. B., Hartmann, Bolette, Holst, Jens Juul & Madsbad, Sten, 1 Apr 2016, In: American Journal of Physiology: Endocrinology and Metabolism. 310, 7, p. E505-E514 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Searching for the physiological role of glucose-dependent insulinotropic polypeptide
Holst, Jens Juul, Windeløv, Johanne Agerlin, Boer, G. A., Pedersen, Jens, Svendsen, B., Christensen, M., Torekov, Signe Sørensen, Asmar, M., Hartmann, Bolette & Nissen, A., 1 Apr 2016, In: Journal of Diabetes Investigation. 7, S1, p. 8-12 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hepatic mitochondrial oxidative phosphorylation is normal in obese patients with and without type 2 diabetes
Lund, M. T., Kristensen, M. D., Hansen, M., Tveskov, L., Floyd, A. K., Støckel, M., Vainer, B., Poulsen, Steen Seier, Helge, Jørn Wulff, Prats Gavalda, Clara & Dela, Flemming, 6 Apr 2016, In: The Journal of Physiology. 594, 15, p. 4351-4358 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increased Risk for Other Cancers in Addition to Breast Cancer for CHEK2*1100delC Heterozygotes Estimated From the Copenhagen General Population Study
Näslund-Koch, C., Nordestgaard, Børge & Bojesen, Stig Egil, 10 Apr 2016, In: Journal of Clinical Oncology. 34, 11, p. 1208-16 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Serum 25-Hydroxyvitamin D Status and Longitudinal Changes in Weight and Waist Circumference: Influence of Genetic Predisposition to Adiposity
Larsen, S. C., Ängquist, Lars, Moldovan, M., Huikari, V., Sebert, S., Cavadino, A., Ahluwalia, Tarun Veer Singh, Skaaby, T., Linneberg, Allan René, Husemoen, L. L. N., Toft, U., Pedersen, Oluf Borbye, Hansen, T., Herzig, K., Jarvelin, M., Power, C., Hypponen, E., Heitmann, Berit & Sørensen, Thorkild I.A., 14 Apr 2016, In: P L o S One. 11, 4, p. 1-18 e0153611.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Human Variant of Glucose-Regulated Protein 94 That Inefficiently Supports IGF Production
Marzec, Michal Tomasz, Hawkes, C. P., Eletto, D., Boyle, S., Rosenfeld, R. G., Hwa, V., Wit, J. M., van Duyvenvoorde, H. A., Oostdijk, W., Losekoot, M., Pedersen, Oluf Borbye, Yeap, B. B., Flicker, L., Barzilai, N., Atzmon, G., Grimberg, A. & Argon, Y., May 2016, In: Endocrinology. 157, 5, p. 1914-1928 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci
Ellinghaus, D., Jostins, L., Spain, S. L., Cortes, A., Bethune, J., Han, B., Park, Y. R., Raychaudhuri, S., Pouget, J. G., Hübenthal, M., Folseraas, T., Wang, Y., Esko, T., Metspalu, A., Westra, H-J., Franke, L., Pers, T. H., Weersma, R. K., Collij, V., D'Amato, M. & 26 others, , May 2016, In: Nature Genetics. 48, 5, p. 510-521 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association of Pre-Pregnancy Body Mass Index, Pregnancy-Related Weight Changes, and Parity With the Risk of Developing Degenerative Musculoskeletal Conditions
Bliddal, M., Pottegård, A., Kirkegaard, H., Olsen, J., Jørgensen, J. S., Sørensen, Thorkild I.A., Dreyer, L. & Nohr, E. A., May 2016, In: Arthritis & Rheumatism. 68, 5, p. 1156-64 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Combined insulin deficiency and endotoxin exposure stimulate lipid mobilization and alter adipose tissue signaling in an experimental model of ketoacidosis in subjects with type 1 diabetes: A randomized, controlled, cross over trial
Svart, M., Kampmann, U., Voss, T., Pedersen, S. B., Johannsen, M., Rittig, N., Poulsen, P. L., Nielsen, Thomas Svava, Jessen, N. & Møller, N., May 2016, In: Diabetes. 65, 5, p. 1380-6 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Diabetic and nondiabetic patients with nonalcoholic fatty liver disease have an impaired incretin effect and fasting hyperglucagonaemia
Junker, A. E., Gluud, Lise Lotte, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, May 2016, In: Journal of Internal Medicine. 279, 5, p. 485–493 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of antibiotics on gut microbiota, glucose metabolism and bodyweight regulation: a review of the literature
Mikkelsen, K. H., Allin, K. H. & Knop, Filip Krag, May 2016, In: Diabetes, Obesity and Metabolism. 18, 5, 444–453.Research output: Contribution to journal › Review › Research › peer-review
- Published
Getting from A to B-exploring the activation motifs of the class B adhesion G protein-coupled receptor subfamily G member 4/GPR112
Cornelia Peeters, M., Mos, I., Lenselink, E. B., Lucchesi, M., IJzerman, A. P. & Schwartz, Thue W., May 2016, In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 30, 5, p. 1836-1848 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-1 does not have acute effects on central or renal hemodynamics in patients with type 2 diabetes without nephropathy
Asmar, A., Simonsen, L., Asmar, M., Madsbad, Sten, Holst, Jens Juul, Frandsen, E., Moro, C., Sorensen, Charlotte Mehlin, Jonassen, Thomas & Bulow, J., May 2016, In: American Journal of Physiology: Endocrinology and Metabolism. 310, 9, p. E744-E753 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Observationally and Genetically High YKL-40 and Risk of Venous Thromboembolism in the General Population: Cohort and Mendelian Randomization Studies
Kjaergaard, A. D., Johansen, Julia Sidenius, Bojesen, Stig Egil & Nordestgaard, Børge, May 2016, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 36, 5, p. 1030-1036 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Oxyntomodulin Identified as a Marker of Type 2 Diabetes and Gastric Bypass Surgery by Mass-spectrometry Based Profiling of Human Plasma
Albrechtsen, Nicolai Jacob Wewer, Hornburg, D., Albrechtsen, Reidar, Svendsen, B., Toräng, S., Jepsen, Sara Lind, Kuhre, Rune Ehrenreich, Hansen, M., Janus, C., Floyd, A., Lund, Asger Bach, Vilsbøll, Tina, Knop, Filip Krag, drb459, drb459, Deacon, Carolyn F., Meissner, F., Mann, Matthias, Holst, Jens Juul & Hartmann, Bolette, May 2016, In: EBioMedicine. 7, p. 112-120 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Anxiolytic-Like Effects of Increased Ghrelin Receptor Signaling in the Amygdala
Jensen, M., Ratner, C., Rudenko, Olga, Christiansen, S. H., Skov, Louise Julie, Johnsen, Cecilie Hundahl, Woldbye, David Paul Drucker & Holst, Birgitte, 1 May 2016, In: International Journal of Neuropsychopharmacology. 19, 5, 12 p., pyv123.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cholecystokinin-Induced Gallbladder Emptying and Single-Dose Metformin Elicit Additive Glucagon-Like Peptide-1 Responses
Rohde, U., Sonne, D. P., Christensen, M., Hansen, M., Brønden, A., Toräng, S., Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 1 May 2016, In: The Journal of clinical endocrinology and metabolism. 101, 5, p. 2076-2083Research output: Contribution to journal › Journal article › Research › peer-review
- Published
FAP finds FGF21 easy to digest
Gillum, M. P. & Potthoff, M. J., 1 May 2016, In: Biochemical Journal. 473, 9, p. 1125-7 3 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Komplement C3 und risiko fur venose thromboembolie
Nørgaard, I., Nielsen, S. F. & Nordestgaard, Børge, 1 May 2016, In: Vasomed. 28, 3, p. 134-135 2 p.Research output: Contribution to journal › Comment/debate › Research
- Published
Mutations causative of familial hypercholesterolaemia: screening of 98 098 individuals from the Copenhagen General Population Study estimated a prevalence of 1 in 217
Benn, M., Watts, G. F., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 1 May 2016, In: European Heart Journal. 37, 17, p. 1384-94 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nicotinamide riboside is a major NAD+ precursor vitamin in cow milk
Trammell, Sam, Y., L., Redpath, P., Migaud, M. E. & Brenner, C., 1 May 2016, In: Journal of Nutrition. 146, 5, p. 957-963 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Placebo-Controlled Study on the Effects of the Glucagon-Like Peptide-1 Mimetic, Exenatide, on Insulin Secretion, Body Composition and Adipokines in Obese, Client-Owned Cats
Hoelmkjaer, K. M., Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Cronin, A. M., Nielsen, Dorte Hald, Mandrup-Poulsen, Thomas & Bjørnvad, Charlotte Reinhard, 2 May 2016, In: P L o S One. 11, 5, 18 p., e0154727.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
C4.4A gene ablation is compatible with normal epidermal development and causes modest overt phenotypes
Kriegbaum, M. C., Jacobsen, B., Fuchtbauer, A., Hansen, Gert Helge, Christensen, I. J., Friis, Carsten, Persson, M., Engelholm, Lars Henning, Madsen, A. N., Di Meo, I., Lund, I. K., Holst, Birgitte, Kjær, Andreas, Laerum, O. D., Fuchtbauer, E. & Ploug, Michael, 12 May 2016, In: Scientific Reports. 6, 25833.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Role of Conserved Disulfide Bridges and Aromatic Residues in Extracellular Loop 2 of Chemokine Receptor CCR8 for Chemokine and Small Molecule Binding
Barington, L., Rummel, P. C., Lückmann, Michael, Pihl, H., Larsen, Olav, Daugvilaite, V., Johnsen, A. H., Frimurer, Thomas Michael, Karlshøj, S. & Rosenkilde, Mette, 19 May 2016, In: The Journal of Biological Chemistry. 291, 31, p. 16208-16220Research output: Contribution to journal › Journal article › Research › peer-review
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Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
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Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets
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The isoenzyme pattern of LDH does not play a physiological role; except perhaps during fast transitions in energy metabolism
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Determinants of plasma levels of proglucagon and the metabolic impact of glucagon receptor signalling: a UK Biobank study
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The interplay between birth weight and obesity in determining childhood and adolescent cardiometabolic risk
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Targeting postsynaptic glutamate receptor scaffolding proteins PSD-95 and PICK1 for obesity treatment
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