Novo Nordisk Foundation Center for Basic Metabolic Research

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  1. 1993
  2. Published

    Normalization of fasting hyperglycaemia by exogenous-glucagon-like peptide 1 (7-36 amide) in type 2 (non-insulin-dependent) diabetic patients

    Nauck, M. A., Kleine, N., Ørskov, C., Holst, Jens Juul, Willms, B. & Creutzfeldt, W., 1993, In: Diabetologia. 36, p. 741-744

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    On the effects of human galanin in man

    Holst, Jens Juul, Bersani, M., Hvidberg, A., Knigge, Ulrich, Christiansen, E. M., Madsbad, Sten, Harling, H. & Kofod, H., 1993, In: Diabetologia. 36, 7, p. 653-657 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Pancreas and gut hormone responses to oral glucose and intravenous glucagon in cystic fibrosis patients with normal, impaired and diabetic glucose tolerance

    Laang, S., Thorsteinsson, B., Røder, M. E., Ørskov, Cathrine, Holst, Jens Juul, Nerup, J. & Koch, C., 1993, In: Acta Endoctrinologica. 128, p. 207-214

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Postprandial release of glucagon-like peptide-1, pancreatic glucagon, and insulin after esophageal resection

    Miholic, J., Ørskov, C., Holst, Jens Juul, Kotzerke, J. & Pichlmayr, R., 1993, In: Digestion. 54, p. 73-78

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Preserved incretin activity of glucagon-like peptide 1 (7-36 amide) but not of synthetic human gastric inhibitory polypeptide in patients with type-2 diabetes mellitus

    Nauck, M. A., Heimesaat, M. M., Ørskov, C., Holst, Jens Juul, Ebert, R. & Creutzfeldt, W., 1993, In: Journal of Clinical Investigation. 91, p. 301-307

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Regulation of secretion of pancreatic spasmolytic polypeptide from porcine pancreas

    Rasmussen, T. N., Harling, H., Thim, L., Pierzynowski, S., Weström, B. R. & Holst, Jens Juul, 1993, In: The American Journal of Physiology. p. G22-G29

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Release of immunoreactive somatostatin, vasoactive intestinal polypeptide (VIP), and galanin during propulsive complexes in isolated pig ileum

    Schmidt, P., Rasmussen, T. N. & Holst, Jens Juul, 1993, In: Peptides. Vol. 14, p. 215-220

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    The dissociation of tumor-induced weight loss from hypoglycemia in a transplantable pluripotent rat islet tumor results in the segregation of stable *Ga- and *Gb-cell tumor phenotypes

    Madsen, O. D., Karlsen, G., Nielsen, E., Lund, K., Kofod, H., Welinder, B., Rehfeld, J. F., Larsson, L., Steiner, D. F., Holst, Jens Juul & Michelsen, B. K., 1993, In: Endokrinologiya. vol. 133, no. 5, p. 2022-2030

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    The effect of glucose on the plasma concentration of somatostatin during caloric deficiency in man

    Øktedalen, O., Opstad, P. K. & Holst, Jens Juul, 1993, In: Scandinavian Journal of Gastroenterology. 28, p. 652-656

    Research output: Contribution to journal › Journal article › Research

  11. Published

    Transmitters in the control of gastrin and acid secretion in the pig stomach

    Holst, Jens Juul, Nørre Ramussen, T., Schmidt, P. & Poulsen, S. S., 1993, Gastrin. New York: Raven Press, p. 243-258

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  12. Published

    Truncated GLP-1 (proglucagon 78-107-amide) inhibits gastric and pancreatic functions in man

    Wettergren, A., Schjoldager, B., Mortensen, P. E., Myhre, J., Christiansen, J. & Holst, Jens Juul, 1993, In: Digestive Diseases and Sciences. Vol. 38, no. 4, p. 665-673

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Vasoactive intestinal peptide (VIP) stimulates androstenedione release in isolated perfused pig adrenals

    Bornstein, S. R., Ehrhart-Bornstein, M., Stromeyer, H. G., Adler, G., Scherbaum, W. A. & Holst, Jens Juul, 1993, In: Life Sciences. 52, p. 135-140

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Biological effects and metabolic rates of glucagonlike peptide-1 7-36 amide and glucagonlike peptide-1 7-37 in healthy subjects are indistinguishable

    Ørskov, Cathrine, Wettergren, A. & Holst, Jens Juul, May 1993, In: Diabetes. 42, 5, p. 658-61 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Controlled trial of lambda-cyhalothrin impregnated bed nets and Maloprim chemosuppression to control malaria in children living in a holoendemic area of Sierra Leone, west Africa. Study design and preliminary results

    Petersen, E., Marbiah, N. T., Magbiti, E., Lines, J. D., Maude, G. H., Høgh, Birthe, Curtis, C., Greenwood, B. & Bradley, D., Jul 1993, In: Parassitologia. 35 Suppl, p. 81-5 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Glutamate rich Plasmodium falciparum antigen (GLURP)

    Høgh, Birthe, Thompson, R., Zakiuddin, I. S., Boudin, C. & Borre, M., Jul 1993, In: Parassitologia. 35 Suppl, p. 47-50 4 p.

    Research output: Contribution to journal › Review › Research › peer-review

  17. Published

    Classification of clinical falciparum malaria and its use for the evaluation of chemosuppression in children under six years of age in Liberia, west Africa

    Høgh, Birthe, Marbiah, N. T., Petersen, E., Dolopaye, E., Willcox, M., Björkman, A., Hanson, A. P. & Gottschau, A., Aug 1993, In: Acta Tropica. 54, 2, p. 105-15 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Radiojodbehandling af recidiverende hypertyreose hos patienter som tidligere er behandlet for diffus toksisk struma med subtotal strumektomi

    drb459, drb459 & Laurberg, P., 2 Aug 1993, In: Ugeskrift for Laeger. 155, 31, p. 2403-5 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    The effect of intensive insulin therapy on the insulin-regulatable glucose transporter (GLUT4) expression in skeletal muscle in type 1 diabetes

    Andersen, P. H., drb459, drb459, Lund, S., Vedel, P., Junker, S., Kahn, B. B. & Pedersen, Oluf Borbye, Oct 1993, In: Diabetic Medicine. 10, 8, p. 699-706 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Aminoacid polymorphisms of insulin receptor substrate-1 in non-insulin-dependent diabetes mellitus

    Almind, K., Bjørbaek, C., drb459, drb459, Hansen, Torben, Echwald, S. M. & Pedersen, Oluf Borbye, 2 Oct 1993, In: Lancet. 342, 8875, p. 828-32 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    The dissociation of tumor-induced weight loss from hypoglycemia in a transplantable pluripotent rat islet tumor results in the segregation of stable alpha- and beta-cell tumor phenotypes

    Madsen, O. D., Karlsen, C., Nielsen, E., Lund, K., Kofod, H., Welinder, B., Rehfeld, Jens Frederik, Larsson, L. I., Steiner, D. F. & Holst, Jens Juul, Nov 1993, In: Endocrinology. 133, 5, p. 2022-30 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Expression of insulin receptor spliced variants and their functional correlates in muscle from patients with non-insulin-dependent diabetes mellitus

    Hansen, Torben, Bjørbaek, C., drb459, drb459, Grønskov, K., Bak, J. F. & Pedersen, Oluf Borbye, Dec 1993, In: The Journal of clinical endocrinology and metabolism. 77, 6, p. 1500-5 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    GLUT-4 content in plasma membrane of muscle from patients with non-insulin-dependent diabetes mellitus

    Lund, S., drb459, drb459, Andersen, P. H., Schmitz, O., Gøtzsche, L. B. & Pedersen, O., Dec 1993, In: American Journal of Physiology (Consolidated). 265, 6 Pt 1, p. E889-97

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. 1994
  25. Published

    Atrial natriuretic peptide-like immunoreactive material (ANP-L1) is released from the adrenal gland by splanchnic nerve stimulation

    Duntas, L., Bornstein, S. R., Scherbaum, W. & Holst, Jens Juul, 1994, In: Exp.Clin.Endocrinol.. 101, p. 371-373

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Cholecystokinin is a negative regulator of gastric acid secretion and postprandial release of gastrin in humans.

    Schmidt, W. E., Schenk, S., Nustede, R., Rovati, L. C., Holst, Jens Juul, Fölsch, U. & Creutzfeldt, W., 1994, In: Today in Medicine. Gastroenterology. 107, p. 1610-1620

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Decreased postprandial thermogenesis and fat oxidation, but increased fullness after a high-fiber meal compared to a low-fiber meal

    Raben, A. B., Christensen, N. J., Madsen, J. J. V., Holst, Jens Juul & Astrup, A., 1994, In: Am. J. Clin. Nutr.. 59, p. 1386-1394

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Effect of glucagon-like peptide-1 (proglucagon 78 - 107 amide) on hepatic glucose production in healthy man

    Hvidberg, A., Nielsen, M. T., Hilsted, J., Ørskov, Cathrine & Holst, Jens Juul, 1994, In: Metabolism. 43, p. 104-108

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Effect of glucagon-like peptide-1 (proglucagon 78-107 amide) on hepatic glucose production in healthy man

    Hvidberg, A., Nielsen, M. T., Hilsted, J., Holst, Jens Juul & Ørskov, C., 1994, In: Metabolism. 43, p. 104-108

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Evidence for an abnormal postprandial response to a high-fat meal in women predisposed to obesity

    Raben, A., Andersen, H. B., Christensen, N. J., Madsen, J. J. V., Holst, Jens Juul & Astrup, A., 1994, In: Am. J. Physiol.. 267, p. E549-E559

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Evidence for an abnormal postprandial response to a high-fat meal in women predisposed to obesity

    Raben, Anne, Andersen, H. B., Christensen, N. J., Madsen, J., Holst, Jens Juul & Astrup, A., 1994, In: American Journal of Physiology: Endocrinology and Metabolism. 267, 4 part 1, p. E549-E559 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Exendin-4 and exendin (9-39)NH*U2-agonist and antagonist, respectively, at the rat parietal cell receptor for glucagon-like peptide-1 (7-36)NH*U2

    Schepp, W., Schmidtler, J. & Holst, Jens Juul, 1994, In: Eur. J. Pharmacol.. 269, p. 183-191

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Glucagon and other proglucagon-derived peptides

    Holst, Jens Juul & Ørskov, Cathrine, 1994, Gut Peptides: Biochemistry and Physiology. New York: Raven Press, p. 305-340

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  34. Published

    Glucagon-like peptide 1: on its way to clinical application

    Göke, B., Göke, R., Holst, Jens Juul & Ørskov, C., 1994, In: Digestion. 54, p. 339-340

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Glucagon-like peptide-1 (GLP-1) - A newly discovered Gl Hormone. Review.

    Holst, Jens Juul, 1994, In: Today in Medicine. Gastroenterology. 107, p. 1848-1855

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Glucagon-like peptide-1 (GLP-1) 7-36 amide and peptide YY from L-cell in the ileal mucosa are potent inhibitors of vagally induced gastric acid secretion in man

    Wettergren, A., Petersen, H., Ørskov, Cathrine, Christiansen, J., Sheikh, S. & Holst, Jens Juul, 1994, In: Scandinavian Journal of Gastroenterology. 29, p. 501-505

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Gut hormones and intestinal function

    Holst, Jens Juul & Schmidt, P., 1994, The Gut as an Endocrine Organ. Clinics in Endocrinology and Metabolism, Vol 8. Bailliere, p. 137-164

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  38. Published

    Human and rodent muscle Na(+)-K(+)-ATPase in diabetes related to insulin, starvation, and training

    Schmidt, Thomas Andersen, Hasselbalch, Steen, Farrell, P. A., drb459, drb459 & Kjeldsen, K., 1994, In: Journal of Applied Physiology. 76, 5, p. 2140-6 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Immunoneutralization of endogenous glucagon with monoclonal glucagon antibody normalizes hyperglycemia in moderately streptozotocin-diabetes rats

    Brand, C. L., Rolin, B., Jørgensen, P. N., Svendsen, J. S. & Holst, Jens Juul, 1994, In: Diabetologia. 37, p. 985-993

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Isolated organs as replacements for vertebrate animals

    Holst, Jens Juul, 1994, Handbook of Laboratory Animal Science. USA: CRC Press, p. 397-408

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  41. Published

    Nitric oxide (NO) is an important element in neurally induced pancreatic exocrine secretion in pigs

    Holst, Jens Juul, Rasmussen, T. N. & Schmidt, P., 1994, In: Am J Physiology. 29, p. G206-G213

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Peptidergic control of amylase secretion from the rat parotid gland

    Goll, R., Poulsen, J. H., Schmidt, P., Schjoldager, B., Poulsen, S. S. & Holst, Jens Juul, 1994, In: Regulatory Peptides. 51, p. 237-254

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Pigs produce only a single form of CGRP, part of which is processed to N- and C-terminal fragments

    Rasmussen, T. N., Bersani, M., Johnsen, A. H., Kofod, H. & Holst, Jens Juul, 1994, In: Peptides. 15, 1, p. 89-94 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Postprandial lipid oxidation reduced and carbohydrate oxidation increased in postobese subjects

    Raben, A., Andersen, H. B., Christensen, N. J., Madsen, J., Holst, Jens Juul & Astrup, A., 1994, Obesity in Europe. John Libbey, p. 135-137

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  45. Published

    Production and secretion of amidated and glycine-extended glucagon-like peptide-1 (GLP) in man

    Ørskov, C., Rabenhøj, L., Kofod, H., Wettergren, A. & Holst, Jens Juul, 1994, In: Diabetes. 43, p. 535-39

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Proglucagon processing in porcine and human pancreas

    Holst, Jens Juul, Bersani, M., Johnsen, A. H., Kofod, H., Hartmann, Bolette & Ørskov, Cathrine, 1994, In: Journal of Biological Chemistry. 269, 29, p. 18827-33 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Rat parietal cell receptors for GLP-1 (7-36) amide: Northern blot, cross-linking, and radioligand binding

    Schmidtler, J., Dehne, K., Allescher, H. D., Schusdziarra, V., Classen, M., Holst, Jens Juul, Polack, A. & Schepp, W., 1994, In: Am. J. Physiol.. 267, p. G423-G432

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Resistant starch: The effect on postprandial glycemia, hormonal response and satiety

    Raben, A., Tagliabue, A., Christensen, N. J., Madsen, J. J. V., Holst, Jens Juul & Astrup, A., 1994, In: Am. J. Clin. Nutr.. 60, p. 544-551

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Secretion of glucagon-like peptide-1 and reactive hypoglycemia after partial gastrectomy

    Andreasen, J., Ørskov, Cathrine & Holst, Jens Juul, 1994, In: Digestion. 55, p. 221-228

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Secretion of pancreastatins from isolated, perfused porcine adrenal glands

    Børglum, T., Fahrenkrug, J. & Holst, Jens Juul, 1994, In: Peptides. 15, p. 519-527

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    Secretion of pancreastatins from the porcine gastrointestinal tract

    Børglum, J. T., Holst, Jens Juul & Fahrenkrug, J., 1994, In: Scandinavian Journal of Gastroenterology. 29, p. 376-384

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Subcutaneous injection of glucagon-like insulintropic peptide reduces postprandial glycemia in non-insulin dependent diabetes

    Gutniak, M. K., Linde, B., Holst, Jens Juul & Efendic, S., 1994, In: Diabetes Care. 17, p. 1039-1044

    Research output: Contribution to journal › Journal article › Research › peer-review

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