Novo Nordisk Foundation Center for Basic Metabolic Research

  1. 2016
  2. Published

    Transcriptomic profiling of pancreatic alpha, beta and delta cell populations identifies delta cells as a principal target for ghrelin in mouse islets

    Adriaenssens, A. E., Svendsen, B., Lam, B. Y. H., Yeo, G. S. H., Holst, Jens Juul, Reimann, F. & Gribble, F. M., Oct 2016, In: Diabetologia. 59, 10, p. 2156-2165 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Assessing the role of insulin-like growth factors and binding proteins in prostate cancer using Mendelian randomization: Genetic variants as instruments for circulating levels

    Bonilla, C., Lewis, S. J., Rowlands, M-A., Gaunt, T. R., Davey-Smith, G., Gunnell, D., Palmer, T. M., Donovan, J. L., Hamdy, F. C., Neal, D. E., Eeles, R., Easton, D., Kote-Jarai, Z., Al Olama, A. A., Benlloch, S., Muir, K., Giles, G., Wiklund, F., Grönberg, H., Haiman, C. A. & 22 others, Schleutker, J., Nordestgaard, Børge, Travis, R. C., Pashayan, N., Khaw, K., Stanford, J. L., Blot, W. J., Thibodeau, S. N., Maier, C., Kibel, A. S., Cybulski, C., Cannon-Albright, L., Brenner, H., Park, J., Kaneva, R., Batra, J., Teixeira, M. R., Pandha, H., PRACTICAL consortium, P. C., Lathrop, M., Martin, R. M. & Holly, J. M. P., 1 Oct 2016, In: International Journal of Cancer. 139, 7, p. 1520-1533 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Gene set analysis for interpreting genetic studies

    Pers, Tune H, 1 Oct 2016, In: Human Molecular Genetics. 25, R2, p. R133-R140 8 p.

    Research output: Contribution to journalReviewResearchpeer-review

  5. Published

    Inflammatory biomarkers and risk of cancer in 84,000 individuals from the general population

    Allin, K. H., Bojesen, Stig Egil & Nordestgaard, Børge, 1 Oct 2016, In: International Journal of Cancer. 139, 7, p. 1493-500 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Patient survival and tumor characteristics associated with CHEK2:p.I157T - findings from the Breast Cancer Association Consortium

    Muranen, T. A., Blomqvist, C., Dörk, T., Jakubowska, A., Heikkilä, P., Fagerholm, R., Greco, D., Aittomäki, K., Bojesen, S. E., Shah, M., Dunning, A. M., Rhenius, V., Hall, P., Czene, K., Brand, J. S., Darabi, H., Chang-Claude, J., Rudolph, A., Nordestgaard, B. G., Couch, F. J. & 24 others, Hart, S. N., Figueroa, J., García-Closas, M., Fasching, P. A., Beckmann, M. W., Li, J., Liu, J., Andrulis, I. L., Winqvist, R., Pylkäs, K., Mannermaa, A., Kataja, V., Lindblom, A., Margolin, S., Lubinski, J., Dubrowinskaja, N., Bolla, M. K., Dennis, J., Michailidou, K., Wang, Q., Easton, D. F., Pharoah, P. D. P., Schmidt, M. K. & Nevanlinna, H., 3 Oct 2016, In: Breast Cancer Research (Online). 18, 15 p., 98.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Signals from the gut microbiota to distant organs in physiology and disease

    Schroeder, B. O. & Bäckhed, G. F., 6 Oct 2016, In: Nature Medicine. 22, 10, p. 1079-1089 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Chemoproteomic, biochemical and pharmacological approaches in the discovery of inhibitors targeting human α/β-hydrolase domain containing 11 (ABHD11)

    Navia-Paldanius, D., Patel, J. Z., López Navarro, M., Jakupovic, Hermina, Goffart, S., Pasonen-Seppänen, S., Nevalainen, T. J., Jääskeläinen, T., Laitinen, T., Laitinen, J. T. & Savinainen, J. R., 10 Oct 2016, In: European Journal of Pharmaceutical Sciences. 93, p. 253-263 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Nicotinamide riboside is uniquely and orally bioavailable in mice and humans

    Trammell, Sam, Schmidt, M. S., Weidemann, B. J., Redpath, P., Jaksch, F., Dellinger, R. W., Li, Z., Abel, E. D., Migaud, M. E. & Brenner, C., 10 Oct 2016, In: Nature Communications. 7, 12948.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Distal, not proximal, colonic acetate infusions promote fat oxidation and improve metabolic markers in overweight/obese men

    van der Beek, C. M., Canfora, E. E., Lenaerts, K., Troost, F. J., Damink, S. W. M. O., Holst, Jens Juul, Masclee, A. A. M., Dejong, C. H. C. & Blaak, E. E., 11 Oct 2016, In: Clinical Science. 130, 22, p. 2073-2082 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    NRK1 controls nicotinamide mononucleotide and nicotinamide riboside metabolism in mammalian cells

    Ratajczak, J., Joffraud, M., Trammell, Sam, Ras, R., Canela, N., Boutant, M., Kulkarni, S. S., Rodrigues, M., Redpath, P., Migaud, M. E., Auwerx, J., Yanes, O., Brenner, C. & Cantó, C., 11 Oct 2016, In: Nature Communications. 7, 13103.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Improved pan-specific prediction of MHC class I peptide binding using a novel receptor clustering data partitioning strategy

    Mattsson, A. H., Kringelum, J. V., Garde, C. & Nielsen, M., 20 Oct 2016, In: HLA. 88, 6, p. 287-292 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Resolution of non-alcoholic steatohepatitis after growth hormone replacement in a pediatric liver transplant patient with panhypopituitarism

    Gilliland, T., Dufour, S., Shulman, G. I., Petersen, K. F. & Emre, S. H., 20 Oct 2016, In: Pediatric Transplantation. 20, 8, p. 1157-1163 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Vejle diabetes Biobank: A resource for studies of the etiologies of diabetes and its comorbidities

    Petersen, E. R. B., Nielsen, A. A., Christensen, H., Hansen, Torben, Pedersen, Oluf Borbye, Christensen, C. K. & Brandslund, I., 21 Oct 2016, In: Clinical Epidemiology. 8, p. 393-413 21 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    GPR119 - a major Enteroendocrine Sensor of Dietary Triglyceride Metabolites Co-acting in Synergy with FFA1 (GPR40)

    Ekberg, J. H., Pedersen, M. H., Kristensen, L. V., Madsen, A. N., Engelstoft, M. S., Husted, Anna Sofie, Sichlau, R., Egerod, Kristoffer Lihme, Timshel, P., Kowalski, T. J., Gribble, F. M., Reiman, F., Hansen, Harald S., Howard, A. D., Holst, Birgitte & Schwartz, Thue W., 25 Oct 2016, In: Endocrinology. 157, 12, p. 4561-4569 9 p., en20161334.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Svær overvægt hos børn og unge

    Kloppenborg, J. T. & Holm, Jens-Christian, 31 Oct 2016, In: Ugeskrift for Laeger. 178, 22, p. 2089-2092 4 p., V06160432.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    15-year follow-up of the Second Nordic Mantle Cell Lymphoma trial (MCL2): prolonged remissions without survival plateau

    Eskelund, C. W., Kolstad, A., Jerkeman, M., Räty, R., Laurell, A., Eloranta, S., Smedby, K. E., Husby, S., Pedersen, L. B., Andersen, N. S., Eriksson, M., Kimby, E., Bentzen, H., Kuittinen, O., Lauritzsen, G. F., Nilsson-Ehle, H., Ralfkiaer, E., Ehinger, M., Sundström, C., Delabie, J. & 7 others, Karjalainen-Lindsberg, M., Workman, C. T., Garde, C., Elonen, E., Brown, Peter de Nully, Grønbæk, Kirsten & Geisler, C. H., Nov 2016, In: British Journal of Haematology. 175, 3, p. 410-418 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Airway irritation, inflammation, and toxicity in mice following inhalation of metal oxide nanoparticles

    Larsen, S. T., Jackson, P., Poulsen, Steen Seier, Levin, M., Jensen, K. A., Wallin, H., Nielsen, G. D. & Koponen, I. K., Nov 2016, In: Nanotoxicology. 10, 9, p. 1254-1262 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Associations between childhood height and morphologically different variants of melanoma in adulthood

    Meyle, K. D., Gamborg, M. O., Hølmich, Lisbet Rosenkrantz & Baker, J. L., Nov 2016, In: European journal of cancer (Oxford, England : 1990). 67, p. 99-105 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Disturbed postprandial glucose metabolism and gut hormone responses in non-diabetic patients with psoriasis

    Gyldenløve, M., Vilsbøll, Tina, Holst, Jens Juul, Zachariae, Claus, Skov, L. & Knop, Filip Krag, Nov 2016, In: British Journal of Dermatology. 175, 5, p. 1085–1088

    Research output: Contribution to journalLetterResearchpeer-review

  21. Published

    Feedback suppression of meal-induced glucagon-like peptide-1 (GLP-1) secretion mediated through elevations in intact GLP-1 caused by dipeptidyl peptidase-4 inhibition: a randomized, prospective comparison of sitagliptin and vildagliptin treatment

    Baranov, O., Kahle, M., Deacon, Carolyn F., Holst, Jens Juul & Nauck, M. A., Nov 2016, In: Diabetes, Obesity and Metabolism. 18, 11, p. 1100-1109 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Higher Endogenous Glucose Production during OGTT vs Isoglycemic Intravenous Glucose Infusion

    Lund, Asger Bach, Bagger, J. I., Christensen, Mikkel Bring, Grøndahl, M., van Hall, Gerrit, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, Nov 2016, In: The Journal of Clinical Endocrinology & Metabolism. 101, 11, p. 4377-4384

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Lipoprotein (a) as a cause of cardiovascular disease: insights from epidemiology, genetics, and biology

    Nordestgaard, Børge & Langsted, A., Nov 2016, In: Journal of Lipid Research. 57, 11, p. 1953-1975 23 p.

    Research output: Contribution to journalReviewResearchpeer-review

  24. Published

    Years of life gained by multifactorial intervention in patients with type 2 diabetes mellitus and microalbuminuria: 21 years follow-up on the Steno-2 randomised trial

    Gæde, P., Øllgaard, J. C., Carstensen, Bendix, Rossing, Peter, Lund-Andersen, H., Parving, H. & Pedersen, Oluf Borbye, Nov 2016, In: Diabetologia. 59, 11, p. 2298-2307 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Adipocyte gene expression and DNA methylation patterns differ significantly between lean and obese pigs

    Jacobsen, M. J., Havgaard, Jakob Hull, Mentzel, Caroline M. Junker, Sørensen, P. M., Pundhir, Sachin, Anthon, Christian, Karlskov-Mortensen, Peter, Bruun, Camilla Vibeke Sichlau, Cirera, Susanna, Gorodkin, Jan, Jørgensen, Claus Bøttcher, Barrès, Romain & Fredholm, Merete, 9 Nov 2016, In: Journal of Animal Science. 94, Supplement 4, p. 46-47 2 p., P2019.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  26. Published

    Genetic Correlation between Body Fat Percentage and Cardiorespiratory Fitness Suggests Common Genetic Etiology

    Schnurr, T. M., Gjesing, A. M. P., Sandholt, C. H., Jonsson, Anna Elisabet, Mahendran, Y., Have, C. T., Ekstrøm, Claus Thorn, Bjerregaard, A., Brage, S., Witte, D., Jørgensen, M. E., Aadahl, Mette, Thuesen, B. H., Linneberg, Allan René, Eiberg, Hans Rudolf Lytchoff, Pedersen, Oluf Borbye, Grarup, N., Kilpeläinen, Tuomas O. & Hansen, Torben, 15 Nov 2016, In: P L o S One. 11, 11, 14 p., e0166738.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Building Bridges through Scientific Conferences

    Zierath, Juleen R, 17 Nov 2016, In: Cell. 167, 5, p. 1155-1158 4 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  28. Published

    A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape

    Ried, J. S., Jeff M, J., Chu, A. Y., Bragg-Gresham, J. L., van Dongen, J., Huffman, J. E., Ahluwalia, T. V. S., Cadby, G., Eklund, N., Eriksson, J., Esko, T., Feitosa, M. F., Goel, A., Gorski, M., Hayward, C., Heard-Costa, N. L., Jackson, A. U., Jokinen, E., Kanoni, S., Kristiansson, K. & 256 others, Kutalik, Z., Lahti, J., Luan, J., Mägi, R., Mahajan, A., Mangino, M., Medina-Gomez, C., Monda, K. L., Nolte, I. M., Pérusse, L., Prokopenko, I., Qi, L., Rose, L. M., Salvi, E., Smith, M. T., Snieder, H., Stančáková, A., Ju Sung, Y., Tachmazidou, I., Teumer, A., Thorleifsson, G., van der Harst, P., Walker, R. W., Wang, S. R., Wild, S. H., Willems, S. M., Wong, A., Zhang, W., Albrecht, E., Couto Alves, A., Bakker, S. J. L., Barlassina, C., Bartz, T. M., Beilby, J., Bellis, C., Bergman, R. N., Bergmann, S., Blangero, J., Blüher, M., Boerwinkle, E., Bonnycastle, L. L., Bornstein, S. R., Bruinenberg, M., Campbell, H., Chen, Y. I., Chiang, C. W. K., Chines, P. S., Collins, F. S., Cucca, F., Cupples, L. A., D'Avila, F., de Geus, E. J. C., Dedoussis, G., Dimitriou, M., Döring, A., Eriksson, J. G., Farmaki, A., Farrall, M., Ferreira, T., Fischer, K., Forouhi, N. G., Friedrich, N., Gjesing, A. M. P., Glorioso, N., Graff, M., Grallert, H., Grarup, N., Gräßler, J., Grewal, J., Hamsten, A., Harder, M. N., Hartman, C. A., Hassinen, M., Hastie, N., Hattersley, A. T., Havulinna, A. S., Heliövaara, M., Hillege, H., Hofman, A., Holmen, O., Homuth, G., Hottenga, J., Hui, J., Husemoen, L. L., Hysi, P. G., Isaacs, A., Ittermann, T., Jalilzadeh, S., James, A. L., Jørgensen, T., Jousilahti, P., Jula, A., Justesen, Johanne Marie, Justice, A. E., Kähönen, M., Karaleftheri, M., Tee Khaw, K., Keinanen-Kiukaanniemi, S. M., Kinnunen, L., Knekt, P. B., Koistinen, H. A., Kolcic, I., Kooner, I. K., Koskinen, S., Kovacs, P., Kyriakou, T., Laitinen, T., Langenberg, C., Lewin, A. M., Lichtner, P., Lindgren, C. M., Lindström, J., Linneberg, Allan René, Lorbeer, R., Lorentzon, M., Luben, R., Lyssenko, V., Männistö, S., Manunta, P., Leach, I. M., McArdle, W. L., Mcknight, B., Mohlke, K. L., Mihailov, E., Milani, L., Mills, R., Montasser, M. E., Morris, A. P., Müller, G., Musk, A. W., Narisu, N., Ong, K. K., Oostra, B. A., Osmond, C., Palotie, A., Pankow, J. S., Paternoster, L., Penninx, B. W., Pichler, I., Pilia, M. G., Polašek, O., Pramstaller, P. P., Raitakari, O. T., Rankinen, T., Rao, D. C., Rayner, N. W., Ribel-Madsen, R., Rice, T. K., Richards, M., Ridker, P. M., Rivadeneira, F., Ryan, K. A., Sanna, S., Sarzynski, M. A., Scholtens, S., Scott, R. A., Sebert, S., Southam, L., Sparsø, T. H., Steinthorsdottir, V., Stirrups, K., Stolk, R. P., Strauch, K., Stringham, H. M., Swertz, M. A., Swift, A. J., Tönjes, A., Tsafantakis, E., van der Most, P. J., Van Vliet-Ostaptchouk, J. V., Vandenput, L., Vartiainen, E., Venturini, C., Verweij, N., Viikari, J. S., Vitart, V., Vohl, M., Vonk, J. M., Waeber, G., Widén, E., Willemsen, G., Wilsgaard, T., Winkler, T. W., Wright, A. F., Yerges-Armstrong, L. M., Hua Zhao, J., Carola Zillikens, M., Boomsma, D. I., Bouchard, C., Chambers, J. C., Chasman, D. I., Cusi, D., Gansevoort, R. T., Gieger, C., Hansen, Torben, Hicks, A. A., Hu, F., Hveem, K., Jarvelin, M., Kajantie, E., Kooner, J. S., Kuh, D., Kuusisto, J., Laakso, M., Lakka, T. A., Lehtimäki, T., Metspalu, A., Njølstad, I., Ohlsson, C., Oldehinkel, A. J., Palmer, L. J., Pedersen, Oluf Borbye, Perola, M., Peters, A., Psaty, B. M., Puolijoki, H., Rauramaa, R., Rudan, I., Salomaa, V., Schwarz, Peter, Shudiner, A. R., Smit, J. H., Sørensen, Thorkild I.A., Spector, T. D., Stefansson, K., Stumvoll, M., Tremblay, A., Tuomilehto, J., Uitterlinden, A. G., Uusitupa, M., Völker, U., Vollenweider, P., Wareham, N. J., Watkins, H., Wilson, J. F., Zeggini, E., Abecasis, G. R., Boehnke, M., Borecki, I. B., Deloukas, P., van Duijn, C. M., Fox, C., Groop, L. C., Heid, I. M., Hunter, D. J., Kaplan, R. C., McCarthy, M. I., North, K. E., O'Connell, J. R., Schlessinger, D., Thorsteinsdottir, U., Strachan, D. P., Frayling, T., Hirschhorn, J. N., Müller-Nurasyid, M. & Loos, R. J. F., 23 Nov 2016, In: Nature Communications. 7, 11 p., 13357.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    (1)H-MRS measured ectopic fat in liver and muscle is associated with the metabolic syndrome in Danish girls but not in boys with overweight and obesity

    Nissen, A., Fonvig, C. E., Chabanova, E., Bøjsøe, C., Trier, C., Pedersen, Oluf Borbye, Hansen, Torben, Thomsen, Henrik S. & Holm, Jens-Christian, Dec 2016, In: Obesity Science & Practice. 2, 4, p. 376-384 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    PALB2, CHEK2 and ATM rare variants and cancer risk: data from COGS

    Southey, M. C., Goldgar, D. E., Winqvist, R., Pylkäs, K., Couch, F., Tischkowitz, M., Foulkes, W. D., Dennis, J., Michailidou, K., van Rensburg, E. J., Heikkinen, T., Nevanlinna, H., Hopper, J. L., Dörk, T., Claes, K. B., Reis-Filho, J., Teo, Z. L., Radice, P., Catucci, I., Peterlongo, P. & 31 others, Tsimiklis, H., Odefrey, F. A., Dowty, J. G., Schmidt, M. K., Broeks, A., Hogervorst, F. B., Verhoef, S., Carpenter, J., Clarke, C., Scott, R. J., Fasching, P. A., Haeberle, L., Ekici, A. B., Beckmann, M. W., Peto, J., Dos-Santos-Silva, I., Fletcher, O., Johnson, N., Bolla, M. K., Sawyer, E. J., Tomlinson, I., Kerin, M. J., Miller, N., Marme, F., Bojesen, Stig Egil, Nordestgaard, Børge, Kjær, Susanne Krüger, Høgdall, Estrid Vilma Solyom, Høgdall, Claus Kim, Engelholm, S. A. & Australian Ovarian Cancer Study Group, A. O. C. S. G., Dec 2016, In: Journal of Medical Genetics. 53, 12, p. 800-811

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Depressive symptoms in women's midlife in relation to their body weight before, during and after childbearing years

    Bliddal, M., Pottegård, A., Kirkegaard, H., Olsen, J., Sørensen, Thorkild I.A. & Nohr, E. A., Dec 2016, In: Obesity Science & Practice. 2, 4, p. 415-425 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Disruption of the GH Receptor Gene in Adult Mice Increases Maximal Lifespan in Females

    Junnila, R. K., Duran-Ortiz, S., Suer, O., Sustarsic, E. G., Berryman, D. E., List, E. O. & Kopchick, J. J., Dec 2016, In: Endocrinology. 157, 12, p. 4502-4513

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Excessive gains in BMI during adolescence increase risks of cardiovascular mortality in men

    Baker, J. L., Dec 2016, In: The Lancet Diabetes & Endocrinology. 4, 12, p. 964-966 3 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  34. Published

    Genome-wide analysis identifies 12 loci influencing human reproductive behavior

    Barban, N., Jansen, R., de Vlaming, R., Vaez, A., Mandemakers, J. J., Tropf, F. C., Shen, X., Wilson, J. F., Chasman, D. I., Nolte, I. M., Tragante, V., van der Laan, S. W., Perry, J. R. B., Kong, A., Ahluwalia, T. V. S., Albrecht, E., Yerges-Armstrong, L., Atzmon, G., Auro, K., Ayers, K. & 31 others, Bakshi, A., Ben-Avraham, D., Berger, K., Bergman, A., Bertram, L., Bielak, L. F., Bjornsdottir, G., Bonder, M. J., Broer, L., Bui, M., Barbieri, C., Cavadino, A., Chavarro, J. E., Turman, C., Concas, M. P., Cordell, H. J., Davies, G., Eibich, P., Eriksson, N., Esko, T., Eriksson, J., Falahi, F., Felix, J. F., Fontana, M. A., Franke, L., Gandin, I., Gaskins, A. J., Bisgaard, H., Bønnelykke, Klaus, Waage, J. & BIOS Consortium, B. C., Dec 2016, In: Nature Genetics. 48, 12, p. 1462-1472 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Impact of body composition changes on risk of all-cause mortality in older adults

    Graf, C. E., Herrmann, F. R., Spoerri, A., Makhlouf, A., Sørensen, Thorkild I.A., Ho, S., Karsegard, V. L. & Genton, L., Dec 2016, In: Clinical Nutrition. 35, 6, p. 1499-1505 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Increasing insulin resistance accentuates the effect of triglyceride-associated loci on serum triglycerides during 5 years

    Justesen, Johanne Marie, Andersson, E. A., Allin, K. H., Sandholt, C. H., Jørgensen, T., Linneberg, Allan René, Jørgensen, M. E., Hansen, Torben, Pedersen, Oluf Borbye & Grarup, N., Dec 2016, In: Journal of Lipid Research. 57, 12, p. 2193-2199 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Weight loss and weight maintenance obtained with or without GLP-1 analogue treatment decrease branched chain amino acid levels

    pjx571, pjx571, Iepsen, E. P. W., Galijatovic, E. A. A., Mahendran, Y., Lundgren, J. R., Jonsson, Anna Elisabet, Madsbad, Sten, Holst, Jens Juul, drb459, drb459, Hansen, Torben & Torekov, Signe Sørensen, Dec 2016, In: Metabolomics. 12, 12, p. 1-9 9 p., 181.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Phosphodiesterases in non-neoplastic appearing colonic mucosa from patients with colorectal neoplasia

    Mahmood, B., Damm, M. M. B., Jensen, T. S. R., Backe, M. B., Dahllöf, M. S., Poulsen, Steen Seier, Bindslev, Niels & Hansen, M. B., 7 Dec 2016, In: B M C Cancer. 16, 12 p., 938.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Genetic and environmental influences on adult human height across birth cohorts from 1886 to 1994

    Jelenkovic, A., Hur, Y-M., Sund, R., Yokoyama, Y., Siribaddana, S. H., Hotopf, M., Sumathipala, A., Rijsdijk, F., Tan, Q., Zhang, D., Pang, Z., Aaltonen, S., Heikkila, K., Oncel, S. Y., Aliev, F., Rebato, E., Tarnoki, A. D., Tarnoki, D. L., Christensen, K., Skytthe, A. & 79 others, Kyvik, K. O., Silberg, J. L., Eaves, L. J., Maes, H. H., Cutler, T. L., Hopper, J. L., Ordonana, J. R., Sanchez-Romera, J. F., Colodro-Conde, L., Cozen, W., Hwang, A. E., Mack, T. M., Sun, J., Song, Y., Yang, S., Lee, K., Franz, C. E., Kremen, W. S., Lyons, M. J., Busjahn, A., Nelson, T. L., Whitfield, K. E., Kandler, C., Jang, K. L., Gatz, M., Butler, D. A., Stazi, M. A., Fagnani, C., D'Ippolito, C., Duncan, G. E., Buchwald, D., Derom, C. A., Vlietinck, R. F., Loos, R. J. F., Martin, N. G., Medland, S. E., Montgomery, G. W., Jeong, H., Swan, G. E., Krasnow, R., Magnusson, P. K. E., Pedersen, N. L., Dahl-Aslan, A. K., McAdams, T. A., Eley, T. C., Gregory, A. M., Tynelius, P., Baker, L. A., Tuvblad, C., Bayasgalan, G., Narandalai, D., Lichtenstein, P., Spector, T. D., Mangino, M., Lachance, G., Bartels, M., van Beijsterveldt, T. C. E. M., Willemsen, G., Burt, S. A., Klump, K. L., Harris, J. R., Brandt, I., Nilsen, T. S., Krueger, R. F., McGue, M., Pahlen, S., Corley, R. P., Hjelmborg, J. V. B., Goldberg, J. H., Iwatani, Y., Watanabe, M., Honda, C., Inui, F., Rasmussen, F., Huibregtse, B. M., Boomsma, D. I., Sørensen, Thorkild I.A., Kaprio, J. & Silventoinen, K., 14 Dec 2016, In: eLife. 5, p. 1-14 14 p., e20320.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    The Human Intestinal Microbiome in Health and Disease

    Lynch, S. V. & Pedersen, Oluf Borbye, 15 Dec 2016, In: New England Journal of Medicine. 375, 24, p. 2369-2379 11 p.

    Research output: Contribution to journalReviewResearchpeer-review

  41. Published

    The role of kisspeptin and RFRP in the circadian control of female reproduction

    Beymer, M., Henningsen, J., Bahougne, T. & Simonneaux, V., 15 Dec 2016, In: Molecular and Cellular Endocrinology. 438, p. 89-99 11 p.

    Research output: Contribution to journalReviewResearchpeer-review

  42. Published

    Mass spectrometry imaging of biomarker lipids for phagocytosis and signalling during focal cerebral ischaemia

    Nielsen, M. M. B., Lambertsen, K. L., Clausen, B. H., Meyer, M., Bhandari, D. R., Larsen, S. T., Poulsen, Steen Seier, Spengler, B., Janfelt, Christian & Hansen, Harald S., 22 Dec 2016, In: Scientific Reports. 6, p. 1-14 14 p., 39571.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Proteomics reveals the effects of sustained weight loss on the human plasma proteome

    Geyer, P. E., Albrechtsen, Nicolai Jacob Wewer, Tyanova, S., Grassl, N., Iepsen, E. P. W., Lundgren, J., Madsbad, Sten, Holst, Jens Juul, Torekov, Signe Sørensen & Mann, Matthias, 22 Dec 2016, In: Molecular Systems Biology. 12, 16 p., 901.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Molecular Mechanism of Action for Allosteric Modulators and Agonists in CC-chemokine Receptor 5 (CCR5)

    Karlshøj, S., Amarandi, R. M., Larsen, Olav, Daugvilaite, V., Steen, A., Brvar, M., Pui, A., Frimurer, Thomas Michael, Ulven, Trond & Rosenkilde, Mette, 23 Dec 2016, In: Journal of Biological Chemistry. 291, 52, p. 26860-26874

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. 2017
  46. Published

    A Genome-Wide Association Study of IVGTT-Based Measures of First Phase Insulin Secretion Refines the Underlying Physiology of Type 2 Diabetes Variants

    Wood, A. R., Jonsson, A., Jackson, A. U., Wang, T-N., van Leewen, N., Palmer, N. D., Kobes, S., Deelen, J., Boquete-Vilarino, L., Paananen, J., Stančáková, A., Boomsma, D. I., de Geus, E. J., Eekhoff, E. M., Fritsche, A., Kramer, M., Nijpels, G., Simonis-Bik, A. M. C., van Haeften, T. W., Mahajan, A. & 31 others, Boehnke, M., Bergman, R. N., Tuomilehto, J., Collins, F. S., Mohlke, K. L., Banasik, Karina, Groves, C. J., McCarthy, M. I., Pearson, E. R., Natali, A., Mari, A., Buchanan, T. A., Taylor, K. D., Xiang, A. H., Gjesing, A. P., Grarup, N., Eiberg, Hans Rudolf Lytchoff, Pedersen, Oluf Borbye, Chen, Y., Laakso, M., Norris, J. M., Smith, U., Wagenknecht, L. E., Baier, L., Bowden, D. W., Hansen, Torben, Walker, M., Watanabe, R. M., 't Hart, L. M., Hanson, R. L. & Frayling, T. M., 2017, In: Diabetes. 66, 8, p. 2296-2309

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    A Proposal of the European Association for the Study of Obesity to Improve the ICD-11 Diagnostic Criteria for Obesity Based on the Three Dimensions Etiology, Degree of Adiposity and Health Risk

    Hebebrand, J., Holm, Jens-Christian, Woodward, E., Baker, J. L., Blaak, E., Durrer Schutz, D., Farpour-Lambert, N. J., Frühbeck, G., Halford, J. G. C., Lissner, L., Micic, D., Mullerova, D., Roman, G., Schindler, K., Toplak, H., Visscher, T. L. S. & Yumuk, V., 2017, In: Obesity Facts. 10, 4, p. 284-307 24 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    A genome-wide association study of thyroid stimulating hormone and free thyroxine in Danish children and adolescents

    Nielsen, T. R. H., Appel, E. V. R., Svendstrup, M., Ohrt, J. D., Dahl, M., Fonvig, C. E., Hollensted, M., Have, C. T., Kadarmideen, H. N., Pedersen, Oluf Borbye, Hansen, Torben, Holm, Jens-Christian & Grarup, N., 2017, In: PloS one. 12, 3, 16 p., e0174204.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    A hospital-based child and adolescent overweight and obesity treatment protocol transferred into a community healthcare setting

    Mollerup, P. M., Gamborg, Michael Orland, Trier, C., Bøjsøe, C., Nielsen, T. R. H., Baker, J. L. & Holm, Jens-Christian, 2017, In: PLOS ONE. 12, 3, 17 p., e0173033.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    A study of associations between early DHA status and fatty acid desaturase (FADS) SNP and developmental outcomes in children of obese mothers

    Andersen, K. R., Harsløf, L. B. S., Schnurr, T. M., Hansen, Torben, Hellgren, L. I., Michaelsen, Kim F. & Lauritzen, Lotte, 2017, In: The British Journal of Nutrition. 117, 2, p. 278-286 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Abnormal epigenetic changes during differentiation of human skeletal muscle stem cells from obese subjects

    Davegårdh, C., Broholm, C., Perfilyev, A., Henriksen, T., García-Calzón, S., Peijs, L., Hansen, N. S., Volkov, P., Kjøbsted, Rasmus, Wojtaszewski, Jørgen F P, Pedersen, M., Pedersen, Bente Klarlund, Ballak, D. B., Dinarello, C. A., Heinhuis, B., Joosten, L. A. B., Nilsson, E., Vaag, Allan, Schéele, Camilla Charlotte Nielsen & Ling, C., 2017, In: BMC Medicine. 15, 27 p., 39.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    About this book

    Sandøe, Peter, Jensen, Karsten Klint & Whiteley, Louise, 2017, RCR – A Danish textbook for courses in Responsible Conduct of Research. Jensen, K. K., Whiteley, L. & Sandøe, P. (eds.). 2. ed. Department of Food and Resource Economics, University of Copenhagen, p. 8-11 4 p.

    Research output: Chapter in Book/Report/Conference proceedingPreface/postscriptEducation

  53. Published

    Abscisic acid controls the release of insulin from beta-cells, Glucagon-Like Peptide-1 from intestinal L-cells and glucagon from alpha-cells

    Booz, V., Christiansen, Charlotte Bayer, Kuhre, Rune Ehrenreich, Saltiel, M. Y., Sturla, L., Sociali, G., Zocchi, E., Holst, Jens Juul & Bruzzone, S., 2017, In: European Journal of Clinical Investigation. 47, p. 112-113

    Research output: Contribution to journalConference abstract in journalResearch

  54. Published

    Acetylcholine-related proteins in non-neoplastic appearing colonic mucosa from patients with colorectal neoplasia

    Damm, M. M. B., Jensen, T. S. R., Mahmood, B., Lundh, M., Poulsen, Steen Seier, Bindslev, Niels & Hansen, M. B., 2017, In: Molecular Carcinogenesis. 56, 10, p. 2223-2233 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    Active and Passive Immunization Against Staphylococcus aureus Periprosthetic Osteomyelitis in Rats

    Søe, Niels Henrik, Jensen, N. V., Jensen, Asger Lundorff, Koch, J., Poulsen, Steen Seier, Pier, G. B. & Johansen, Helle Krogh, 2017, In: In Vivo. 31, 1, p. 45-50 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    Addition of rye bran and pea fiber to pork meatballs enhances subjective satiety in healthy men, but does not change glycemic or hormonal responses: A randomized crossover meal test study

    Kehlet, U., Kofod, J., Holst, Jens Juul, Ritz, C., Aaslyng, M. D. & Raben, Anne, 2017, In: Journal of Nutrition. 147, 9, p. 1700-1708 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Adiponectin and leptin as first trimester markers for gestational diabetes mellitus: A cohort study

    Thagaard, I. N., Krebs, Lone, Holm, Jens-Christian, Lange, Theis, Larsen, T. & Christiansen, M., 2017, In: Clinical Chemistry and Laboratory Medicine. 55, 11, p. 1805-1812 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans

    Scott, R. A., Scott, L. J., Mägi, R., Marullo, L., Gaulton, K. J., Kaakinen, M., Pervjakova, N., Pers, T. H., Johnson, A. D., Eicher, J. D., Jackson, A. U., Ferreira, T., Lee, Y., Ma, C., Steinthorsdottir, V., Thorleifsson, G., Qi, L., Van Zuydam, N. R., Mahajan, A., Chen, H. & 155 others, Almgren, P., Voight, B. F., Grallert, H., Müller-Nurasyid, M., Ried, J. S., Rayner, W. N., Robertson, N., Karssen, L. C., van Leeuwen, E. M., Willems, S. M., Fuchsberger, C., Kwan, P., Teslovich, T. M., Chanda, P., Li, M., Lu, Y., Dina, C., Thuillier, D., Yengo, L., Jiang, L., Sparso, T., Kestler, H. A., Chheda, H., Eisele, L., Gustafsson, S., Frånberg, M., Strawbridge, R. J., Benediktsson, R., Hreidarsson, A. B., Kong, A., Sigurðsson, G., Kerrison, N. D., Luan, J., Liang, L., Meitinger, T., Roden, M., Thorand, B., Esko, T., Mihailov, E., Fox, C., Liu, C., Rybin, D., Isomaa, B., Lyssenko, V., Tuomi, T., Couper, D. J., Pankow, J. S., Grarup, N., Have, C. T., Jørgensen, M. E., Jørgensen, T., Linneberg, Allan René, Cornelis, M. C., van Dam, R. M., Hunter, D. J., Kraft, P., Sun, Q., Edkins, S., Owen, K. R., Perry, J. R., Wood, A. R., Zeggini, E., Tajes-Fernandes, J., Abecasis, G. R., Bonnycastle, L. L., Chines, P. S., Stringham, H. M., Koistinen, H. A., Kinnunen, L., Sennblad, B., Mühleisen, T. W., Nöthen, M. M., Pechlivanis, S., Baldassarre, D., Gertow, K., Humphries, S. E., Tremoli, E., Klopp, N., Meyer, J., Steinbach, G., Wennauer, R., Eriksson, J. G., Mӓnnistö, S., Peltonen, L., Tikkanen, E., Charpentier, G., Eury, E., Lobbens, S., Gigante, B., Leander, K., McLeod, O., Bottinger, E. P., Gottesman, O., Ruderfer, D., Blüher, M., Kovacs, P., Tonjes, A., Maruthur, N. M., Scapoli, C., Erbel, R., Jöckel, K., Moebus, S., de Faire, U., Hamsten, A., Stumvoll, M., Deloukas, P., Donnelly, P. J., Frayling, T. M., Hattersley, A. T., Ripatti, S., Salomaa, V., Pedersen, N. L., Boehm, B. O., Bergman, R. N., Collins, F. S., Mohlke, K. L., Tuomilehto, J., Hansen, Torben, Pedersen, Oluf Borbye, Barroso, I., Lannfelt, L., Ingelsson, E., Lind, L., Lindgren, C. M., Cauchi, S., Froguel, P., Loos, R. J., Balkau, B., Boeing, H., Franks, P. W., Gurrea, A. B., Palli, D., van der Schouw, Y. T., Altshuler, D., Groop, L. C., Langenberg, C., Wareham, N. J., Sijbrands, E., van Duijn, C. M., Florez, J. C., Meigs, J. B., Boerwinkle, E., Gieger, C., Strauch, K., Metspalu, A., Morris, A. D., Palmer, C. N., Hu, F. B., Thorsteinsdottir, U., Stefansson, K., Dupuis, J., Morris, A. P., Boehnke, M., McCarthy, M. I. & Prokopenko, I., 2017, In: Diabetes. 66, 11, p. 2888-2902

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    Analysis of 62 hybrid assembled human Y chromosomes exposes rapid structural changes and high rates of gene conversion

    Skov, L., Schierup, M. H., Danish Pan Genome Consortium, D. P. G. C., Sørensen, L. M., Petersen, Bent, Sibbesen, Jonas Andreas, Liu, S., Belling, K. G., Have, C. T., Bork-Jensen, J., Hansen, Torben, Krogh, Anders, Sørensen, Thorkild I.A., Pedersen, Oluf Borbye, Rasmussen, Simon, Kristiansen, Karsten & Brunak, Søren, 2017, In: PLOS Genetics. 13, 8, p. e1006834

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    Archaic adaptive introgression in TBX15/WARS2

    Racimo, Fernando, Gokhman, D., Fumagalli, M., Ko, A., Hansen, Torben, Moltke, Ida, Albrechtsen, Anders, Carmel, L., Huerta-Sánchez, E. & Nielsen, Rasmus, 2017, In: Molecular Biology and Evolution. 34, 3, p. 509-524 16 p., msw283.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published

    Are Adverse Effects of Child Overweight on Risk of Type 2 Diabetes Reversible by Remission to Normal Weight in Young Adulthood?

    Bjerregaard, L. G., Jensen, B. W., Ängquist, Lars, Osler, Merete, Sørensen, Thorkild I.A. & Baker, J. L., 2017, p. A3. 1 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  62. Published

    Association studies of genetic scores of serum vitamin B12 and folate levels with symptoms of depression and anxiety in two danish population studies

    Møllehave, L. T., Skaaby, T., Simonsen, K. S., Thuesen, B. H., Mortensen, Erik Lykke, Sandholt, C. H., Pedersen, Oluf Borbye, Grarup, N., Hansen, Torben & Linneberg, Allan René, 2017, In: European Journal of Clinical Nutrition. 71, p. 1054-1060 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    Biased agonism and allosteric modulation of GPR183- a 7TM receptor also known as EBV-induced EBI2

    Daugvilaite, V., Madsen, C. M., Lückmann, Michael, Castello Echeverria, C., Sailer, A. W., Frimurer, Thomas Michael, Rosenkilde, Mette & Benned-Jensen, T., 2017, In: British Journal of Pharmacology. 174, 13, p. 2031–2042

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. Published

    Bioinformatics for discovery of microbiome variation

    Brejnrod, A. D., 2017, Department of Biology, Faculty of Science, University of Copenhagen.

    Research output: Book/ReportPh.D. thesisResearch

  65. Published

    Cardiovascular safety and benefits of GLP-1 receptor agonists

    Dalsgaard, N. B., Brønden, A., Vilsbøll, Tina & Knop, Filip Krag, 2017, In: Expert Opinion on Drug Safety. 16, 3, p. 351-363 13 p.

    Research output: Contribution to journalReviewResearchpeer-review

  66. Published

    Causal relationship between obesity and serum testosterone status in men: A bi-directional mendelian randomization analysis

    Eriksson, J., Haring, R., Grarup, N., Vandenput, L., Wallaschofski, H., Lorentzen, E., Hansen, Torben, Mellström, D., Pedersen, Oluf Borbye, Nauck, M., Lorentzon, M., Nystrup Husemoen, L. L., Völzke, H., Karlsson, M., Baumeister, S. E., Linneberg, Allan René & Ohlsson, C., 2017, In: PloS one. 12, 4, 15 p., e0176277.

    Research output: Contribution to journalJournal articleResearchpeer-review

  67. Published

    Childhood body mass index and development of type 2 diabetes throughout adult life: A large-scale danish cohort study

    Zimmermann, E., Bjerregaard, L. G., Gamborg, M., Vaag, Allan, Sørensen, Thorkild I.A. & Baker, J. L., 2017, In: Obesity. 25, 5, p. 965-971

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    Clinical Pharmacokinetics and Pharmacodynamics of Albiglutide

    Brønden, A., Knop, Filip Krag & Christensen, Mikkel Bring, 2017, In: Clinical Pharmacokinetics. 56, 7, p. 719-731

    Research output: Contribution to journalReviewResearchpeer-review

  69. Published

    Common breast cancer risk alleles and risk assessment: A study on 35,441 individuals from the Danish general population

    Näslund-Koch, C., Nordestgaard, Børge & Bojesen, Stig Egil, 2017, In: Annals of Oncology. 28, 1, p. 175-181

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. Published

    Comparison of HapMap and 1000 Genomes Reference Panels in a Large-Scale Genome-Wide Association Study

    de Vries, P. S., Sabater-Lleal, M., Chasman, D. I., Trompet, S., Ahluwalia, T. S., Teumer, A., Kleber, M. E., Chen, M-H., Wang, J. J., Attia, J. R., Marioni, R. E., Steri, M., Weng, L-C., Pool, R., Grossmann, V., Brody, J. A., Venturini, C., Tanaka, T., Rose, L. M., Oldmeadow, C. & 66 others, Mazur, J., Basu, S., Frånberg, M., Yang, Q., Ligthart, S., Hottenga, J. J., Rumley, A., Mulas, A., de Craen, A. J. M., Grotevendt, A., Taylor, K. D., Delgado, G. E., Kifley, A., Lopez, L. M., Berentzen, T. L., Mangino, M., Bandinelli, S., Morrison, A. C., Hamsten, A., Tofler, G., de Maat, M. P. M., Draisma, H. H. M., Lowe, G. D., Zoledziewska, M., Sattar, N., Lackner, K. J., Völker, U., McKnight, B., Huang, J., Holliday, E. G., McEvoy, M. A., Starr, J. M., Hysi, P. G., Hernandez, D. G., Guan, W., Rivadeneira, F., McArdle, W. L., Slagboom, P. E., Zeller, T., Psaty, B. M., Uitterlinden, A. G., de Geus, E. J. C., Stott, D. J., Binder, H., Hofman, A., Franco, O. H., Rotter, J. I., Ferrucci, L., Spector, T. D., Deary, I. J., März, W., Greinacher, A., Wild, P. S., Cucca, F., Boomsma, D. I., Watkins, H., Tang, W., Ridker, P. M., Jukema, J. W., Scott, R. J., Mitchell, P., Hansen, Torben, O'Donnell, C. J., Smith, N. L., Strachan, D. P. & Dehghan, A., 2017, In: PLOS ONE. 12, 1, 22 p., e0167742.

    Research output: Contribution to journalJournal articleResearchpeer-review

  71. Published

    Current Therapies That Modify Glucagon Secretion: What Is the Therapeutic Effect of Such Modifications?

    Grøndahl, M. F., Keating, D. J., Vilsbøll, Tina & Knop, Filip Krag, 2017, In: Current Diabetes Reports. 17, 12, 10 p., 128.

    Research output: Contribution to journalReviewResearchpeer-review

  72. Published

    DPP4 gene variation affects GLP-1 secretion, insulin secretion, and glucose tolerance in humans with high body adiposity

    Böhm, A., Wagner, R., Machicao, F., Holst, Jens Juul, Gallwitz, B., Stefan, N., Fritsche, A., Häring, H. & Staiger, H., 2017, In: PloS one. 12, 7, 13 p., e0181880.

    Research output: Contribution to journalJournal articleResearchpeer-review

  73. Published

    Dairy consumption, systolic blood pressure, and risk of hypertension: Mendelian randomization study

    Ding, M., Huang, T., Bergholdt, H. K. M., Sørensen, Thorkild I.A., Linneberg, Allan René, Sandholt, C. H., Pedersen, Oluf Borbye, Hansen, Torben, Kilpeläinen, Tuomas O., CHARGE Consortium, C. C., Nordestgaard, Børge, Ellervik, Christina, Qi, L. & Mendelian Randomization of Dairy Consumption Working Group, M. R. O. D. C. W. G., 2017, In: The BMJ. 356, 10 p., j1000.

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. Published

    Difference in postprandial GLP-1 response despite similar glucose kinetics after consumption of wheat breads with different particle size in healthy men

    Eelderink, C., Noort, M. W. J., Sozer, N., Koehorst, M., Holst, Jens Juul, Deacon, Carolyn F., Rehfeld, Jens Frederik, Poutanen, K., Vonk, R. J., Oudhuis, L. & Priebe, M. G., 2017, In: European Journal of Nutrition. 56, 3, p. 1063-1076 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. Published

    Does the sex of one's co-twin affect height and BMI in adulthood? A study of dizygotic adult twins from 31 cohorts

    Bogl, L. H., Jelenkovic, A., Vuoksimaa, E., Ahrenfeldt, L., Pietiläinen, K. H., Stazi, M. A., Fagnani, C., D'Ippolito, C., Hur, Y-M., Jeong, H-U., Silberg, J. L., Eaves, L. J., Maes, H. H., Bayasgalan, G., Narandalai, D., Cutler, T. L., Kandler, C., Jang, K. L., Christensen, K., Skytthe, A. & 56 others, Kyvik, K. O., Cozen, W., Hwang, A. E., Mack, T. M., Derom, C. A., Vlietinck, R. F., Nelson, T. L., Whitfield, K. E., Corley, R. P., Huibregtse, B. M., McAdams, T. A., Eley, T. C., Gregory, A. M., Krueger, R. F., McGue, M., Pahlen, S., Willemsen, G., Bartels, M., van Beijsterveldt, T. C. E. M., Pang, Z., Tan, Q., Zhang, D., Martin, N. G., Medland, S. E., Montgomery, G. W., Hjelmborg, J. V. B., Rebato, E., Swan, G. E., Krasnow, R., Busjahn, A., Lichtenstein, P., Öncel, S. Y., Aliev, F., Baker, L. A., Tuvblad, C., Siribaddana, S. H., Hotopf, M., Sumathipala, A., Rijsdijk, F., Magnusson, P. K. E., Pedersen, N. L., Aslan, A. K. D., Ordoñana, J. R., Sánchez-Romera, J. F., Colodro-Conde, L., Duncan, G. E., Buchwald, D., Tarnoki, A. D., Tarnoki, D. L., Yokoyama, Y., Hopper, J. L., Loos, R. J. F., Boomsma, D. I., Sørensen, Thorkild I.A., Silventoinen, K. & Kaprio, J., 2017, In: Biology of Sex Differences. 8, 12 p., 14.

    Research output: Contribution to journalJournal articleResearchpeer-review

  76. Published

    Dysregulation of a novel miR-23b/27b-p53 axis impairs muscle stem cell differentiation of humans with type 2 diabetes

    Henriksen, T. I., Davidsen, P. K., Pedersen, M., Schultz, H. S., Hansen, N. S., Larsen, T. J., Vaag, Allan, Pedersen, Bente Klarlund, Nielsen, S. & Schéele, Camilla Charlotte Nielsen, 2017, In: Molecular Metabolism. 6, 7, p. 770-779 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. Published

    EBI2 overexpression in mice leads to B1 B cell expansion and chronic lymphocytic leukemia-(CLL)-like B cell malignancies

    Niss Arfelt, K., Barington, L., Benned-Jensen, T., Kubale, V., Kovalchuk, A. L., Daugvilaite, V., Christensen, Jan Pravsgaard, Thomsen, Allan Randrup, Egerod, Kristoffer Lihme, Bassi, Maria Rosaria, Spiess, Katja, Schwartz, Thue W., Wang, H., Morse, H. C., Holst, Peter Johannes & Rosenkilde, Mette, 2017, In: Blood. 129, 7, p. 866-878

    Research output: Contribution to journalJournal articleResearchpeer-review

  78. Published

    Early life risk factors for testicular cancer: a case-cohort study based on the Copenhagen School Health Records Register

    Piltoft, J. S., Larsen, S. B., Dalton, S. O., Johansen, Christoffer, Baker, J. L., Kristiansen, Luise Cederkvist & Andersen, Ingelise, 2017, In: Acta Oncologica. 56, 2, p. 220-224

    Research output: Contribution to journalJournal articleResearchpeer-review

  79. Published

    Effect of the interaction between diet composition and the PPM1K genetic variant on insulin resistance and β cell function markers during weight loss: results from the Nutrient Gene Interactions in Human Obesity: implications for dietary guidelines (NUGENOB) randomized trial

    Goni, L., Qi, L., Cuervo, M., Milagro, F. I., Saris, W. H., Macdonald, I. A., Langin, D., Astrup, A., Arner, P., Oppert, J. M., Svendstrup, M., Blaak, E., Sørensen, Thorkild I.A., Hansen, Torben & Martinez, J. A., 2017, In: American Journal of Clinical Nutrition. 106, 3, p. 902-908 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  80. Published

    Effects of exogenous glucagon-like peptide-2 and distal bowel resection on intestinal and systemic adaptive responses in rats

    Lai, S. W., de Heuvel, E., Wallace, L. E., Hartmann, Bolette, Holst, Jens Juul, Brindle, M. E., Chelikani, P. K. & Sigalet, D. L., 2017, In: PloS one. 12, 7, 20 p., e0181453.

    Research output: Contribution to journalJournal articleResearchpeer-review

  81. Published

    Enhanced muscle insulin sensitivity after contraction/exercise is mediated by AMPK

    Kjøbsted, Rasmus, Munk-Hansen, N., Birk, Jesper Bratz, Foretz, M., Viollet, B., Björnholm, M., Zierath, Juleen R, Treebak, Jonas Thue & Wojtaszewski, Jørgen F P, 2017, In: Diabetes. 66, 3, p. 598-612 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  82. Published

    Estimates of insulin sensitivity and β-cell function in children and adolescents with and without components of the metabolic syndrome

    Frithioff-Bøjsøe, C., Trier, C., Fonvig, Cilius Esmann, Nissen, A., Kloppenborg, J. T., Mollerup, P. M., Bjerrum, P. J., Pedersen, Oluf Borbye, Hansen, Torben & Holm, Jens-Christian, 2017, In: Pediatric Endocrinology, Diabetes and Metabolism. 23, 3, p. 122-129 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  83. Published

    Exenatide: pharmacokinetics, clinical use, and future directions

    Knop, Filip Krag, Bronden, A. & Vilsbøll, Tina, 2017, In: Expert Opinion on Pharmacotherapy. 18, 6, p. 555-571 17 p.

    Research output: Contribution to journalReviewResearchpeer-review

  84. Published

    Exercise modulates the aortic renin-angiotensin system independently of estrogen therapy in ovariectomized hypertensive rats

    Endlich, P. W., Claudio, E. R. G., Lima, L. C. F., Ribeiro Júnior, R. F., Peluso, A. A. B., Stefanon, I., Bissoli, N. S., Lemos, V. S., Santos, R. A. S. D. & Abreu, G. R. D., 2017, In: Peptides.

    Research output: Contribution to journalJournal articleResearchpeer-review

  85. Published

    FGF21 Is a Sugar-Induced Hormone Associated with Sweet Intake and Preference in Humans

    Søberg, S., Sandholt, C. H., Z. Jespersen, N., Toft, U., L. Madsen, A., Holstein-Rønsbo, Stephanie, Grevengoed, Trisha Jean, Christensen, Karl Bang, Bredie, Wender, Potthoff, M. J., P. J. Solomon, T., Schéele, Camilla Charlotte Nielsen, Linneberg, Allan René, Jørgensen, T., Pedersen, Oluf Borbye, Hansen, Torben, Gillum, M. P. & Grarup, N., 2017, In: Cell Metabolism. 25, 5, p. 1045-1053 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  86. Published

    GIP(3-30)NH2 is a potent competitive antagonist of the GIP receptor and effectively inhibits GIP-mediated insulin, glucagon, and somatostatin release

    wbf943, wbf943, Gabe, M. N., Gasbjerg, Lærke Smidt, Christiansen, Charlotte Bayer, Svendsen, B., Hartmann, Bolette, Holst, Jens Juul & Rosenkilde, Mette, 2017, In: Biochemical Pharmacology. 131, p. 78-88

    Research output: Contribution to journalJournal articleResearchpeer-review

  87. Published

    Genetic Variations in the Human G Protein-coupled Receptor Class C, Group 6, Member A (GPRC6A) Control Cell Surface Expression and Function

    Jorgensen, S., Have, C. T., Underwood, C. R., Johansen, L. D., Wellendorph, Petrine, Gjesing, A. P., Jorgensen, C. V., Quan, S., Rui, G., Inoue, A., Linneberg, Allan René, Grarup, N., Jun, W., Pedersen, Oluf Borbye, Hansen, Torben & Bräuner, Hans, 2017, In: The Journal of Biological Chemistry. 292, 4, p. 1524-1534 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  88. Published

    Genetic correlation between amyotrophic lateral sclerosis and schizophrenia

    McLaughlin, R. L., Schijven, D., Van Rheenen, W., Van Eijk, K. R., O'Brien, M., Kahn, R. S., Ophoff, R. A., Goris, A., Bradley, D. G., Al-Chalabi, A., Van Den Berg, L. H., Luykx, J. J., Hardiman, O., Veldink, J. H., Shatunov, A., Dekker, A. M., Diekstra, F. P., Pulit, S. L., Van Der Spek, R. A. A., Van Doormaal, P. T. C. & 31 others, Sproviero, W., Jones, A. R., Nicholson, G. A., Rowe, D. B., Pamphlett, R., Kiernan, M. C., Bauer, D., Kahlke, T., Williams, K., Eftimov, F., Fogh, I., Ticozzi, N., Lin, K., Millecamps, S., Salachas, F., Meininger, V., Carvalho, M. D., Pinto, S., Mora, J. S., Rojas-Garcyá, R., Polak, M., Chandran, S., Andersen, P. M., Pers, Tune H, Hansen, M., Hansen, T., Li, T., Olsen, L., Rasmussen, H. B., Werge, Thomas & Project MinE GWAS Consortium & Schizophrenia Working Group of the Psychiatric Genomics Consortium, P. M. G. C. &. S. W. G. O. T. P. G. C., 2017, In: Nature Communications. 8, 14774.

    Research output: Contribution to journalJournal articleResearchpeer-review

  89. Published

    Genetic invalidation of Lp-PLA2 as a therapeutic target: Large-scale study of five functional Lp-PLA2-lowering alleles

    Gregson, J. M., Freitag, D. F., Surendran, P., Stitziel, N. O., Chowdhury, R., Burgess, S., Kaptoge, S., Gao, P., Staley, J. R., Willeit, P., Nielsen, S. F., Caslake, M., Trompet, S., Polfus, L. M., Kuulasmaa, K., Kontto, J., Perola, M., Blankenberg, S., Veronesi, G., Gianfagna, F. & 41 others, Männistö, S., Kimura, A., Lin, H., Reilly, D. F., Gorski, M., Mijatovic, V., Munroe, P. B., Ehret, G. B., Thompson, A., Uria-Nickelsen, M., Malarstig, A., Dehghan, A., Vogt, T. F., Sasaoka, T., Takeuchi, F., Kato, N., Yamada, Y., Kee, F., Müller-Nurasyid, M., Ferrières, J., Arveiler, D., Amouyel, P., Salomaa, V., Boerwinkle, E., Thompson, S. G., Ford, I., Wouter Jukema, J., Sattar, N., Packard, C. J., Shafi Majumder, A. A., Alam, D. S., Deloukas, P., Schunkert, H., Samani, N. J., Kathiresan, S., Nordestgaard, Børge, Saleheen, D., Howson, J. M., Di Angelantonio, E., Butterworth, A. S. & Danesh, J., 2017, In: European Journal of Preventive Cardiology. 24, 5, p. 492-504

    Research output: Contribution to journalJournal articleResearchpeer-review

  90. Published

    Genetic modifiers of CHEK2*1100delC-associated breast cancer risk

    Muranen, T. A., Greco, D., Blomqvist, C., Aittomäki, K., Khan, S., Hogervorst, F., Verhoef, S., Pharoah, P. D. P., Dunning, A. M., Shah, M., Luben, R., Bojesen, S. E., Nordestgaard, B. G., Schoemaker, M., Swerdlow, A., García-Closas, M., Figueroa, J., Dörk, T., Bogdanova, N. V., Hall, P. & 56 others, Li, J., Khusnutdinova, E., Bermisheva, M., Kristensen, V., Borresen-Dale, A., Investigators, N., Peto, J., Dos Santos Silva, I., Couch, F. J., Olson, J. E., Hillemans, P., Park-Simon, T., Brauch, H., Hamann, U., Burwinkel, B., Marme, F., Meindl, A., Schmutzler, R. K., Cox, A., Cross, S. S., Sawyer, E. J., Tomlinson, I., Lambrechts, D., Moisse, M., Lindblom, A., Margolin, S., Hollestelle, A., Martens, J. W. M., Fasching, P. A., Beckmann, M. W., Andrulis, I. L., Knight, J. A., Investigators, K., Anton-Culver, H., Ziogas, A., Giles, G. G., Milne, R. L., Brenner, H., Arndt, V., Mannermaa, A., Kosma, V., Chang-Claude, J., Rudolph, A., Devilee, P., Seynaeve, C., Hopper, J. L., Southey, M. C., John, E. M., Whittemore, A. S., Bolla, M. K., Wang, Q., Michailidou, K., Dennis, J., Easton, D. F., Schmidt, M. K. & Nevanlinna, H., 2017, In: Genetics In Medicine. 19, 5, p. 599-603

    Research output: Contribution to journalLetterResearchpeer-review

  91. Published

    Glucagon elimination is increased in patients with type 2 diabetes

    Lund, A. B., Grøndahl, M. F., Bagger, J. I., Holst, Jens Juul, Christensen, M., Vilsbøll, Tina & Knop, Filip Krag, 2017, In: Diabetologia. 60, p. S240-S240

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  92. Published

    Glucagon-Like Peptide 1: A Predictor of Type 2 Diabetes?

    Larsen, M. P. & Torekov, Signe Sørensen, 2017, In: Journal of Diabetes Research. 2017, 13 p., 7583506.

    Research output: Contribution to journalReviewResearchpeer-review

  93. Published

    Hepatocyte MyD88 affects bile acids, gut microbiota and metabolome contributing to regulate glucose and lipid metabolism

    Duparc, T., Plovier, H., Marrachelli, V. G., Van Hul, M., Essaghir, A., Ståhlman, M., Matamoros, S., Geurts, L., Pardo-Tendero, M. M., Druart, C., Delzenne, N. M., Demoulin, J., van der Merwe, S. W., van Pelt, J., Bäckhed, G. F., Monleon, D., Everard, A. & Cani, P. D., 2017, In: Gut. 66, 4, p. 620-632 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  94. Published

    Heterogeneity in glucose response curves during an oral glucose tolerance test and associated cardiometabolic risk

    Hulman, A., Simmons, R. K., Vistisen, D., Tabák, A. G., Dekker, J. M., Alssema, M., Rutters, F., Koopman, A. D. M., Solomon, T. P. J., Kirwan, J. P., Hansen, Torben, Jonsson, Anna Elisabet, Gjesing, A. M. P., Eiberg, Hans Rudolf Lytchoff, Astrup, A., Pedersen, Oluf Borbye, Sørensen, Thorkild I.A., Witte, D. & Færch, K., 2017, In: Endocrine. 55, 2, p. 427-434 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. Published

    High Prevalence of Diabetes-Predisposing Variants in MODY Genes Among Danish Women With Gestational Diabetes Mellitus

    Gjesing, A. M. P., Rui, G., Lauenborg, J., Have, C. T., Hollensted, M., Andersson, E., Grarup, N., Sun, J., Quan, S., Brandslund, I., Damm, Peter, Pedersen, Oluf Borbye, Wang, J. & Hansen, Torben, 2017, In: Endocrine Research. 1, 6, p. 681-690 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  96. Published

    Higher intake of fish and fat is associated with lower plasma s-adenosylhomocysteine: a cross-sectional study

    Lind, M. V., Lauritzen, Lotte, Pedersen, Oluf Borbye, drb459, drb459, Stark, K. D., Hansen, Torben, Ross, A. B. & Kristensen, M. B., 2017, In: Nutrition Research. 46, p. 78-87 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  97. Published

    Histone deacetylase 3 prepares brown adipose tissue for acute thermogenic challenge

    Emmett, M. J., Lim, H., Jager, J., Richter, H. J., Adlanmerini, M., Peed, L. C., Briggs, E. R., Steger, D. J., Ma, Tao, Sims, C. A., Baur, J. A., Pei, L., Won, K., Seale, P., Gerhart-Hines, Zach & Lazar, M. A., 2017, In: Nature Genetics. 546, 7659, p. 544-448

    Research output: Contribution to journalJournal articleResearchpeer-review

  98. Published

    Increased liver fat content in totally pancreatectomised patients

    Bagger, J. I., Lund, A. B., Albrechtsen, Nicolai Jacob Wewer, Christensen, M., Grøndahl, M. F., Hansen, C. P., Storkholm, J., Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2017, In: Diabetologia. 60, S1, p. S572-S573

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  99. Published

    Instrumentalization of eating improves weight loss maintenance in obesity

    Christensen, Bodil Just, Iepsen, E. P. W., Lundgren, J. R., Holm, Lotte, Madsbad, Sten, Holst, Jens Juul & Torekov, Signe Sørensen, 2017, In: Obesity Facts. 10, 6, p. 633-647 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  100. Published

    Intake and sources of gluten in 20- to 75-year-old Danish adults: a national dietary survey

    Hoppe, C., Gøbel, R. J., Kristensen, M. B., Lind, M. V., Matthiessen, J., Christensen, T., Trolle, E., Fagt, S., Madsen, M. L. & Husby, S., 2017, In: European Journal of Nutrition. 56, 1, p. 107-117 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  101. Published

    Intestinal Ralstonia pickettii augments glucose intolerance in obesity

    Udayappan, S. D., Kovatcheva-Datchary, P., Bakker, G. J., Havik, S. R., Herrema, H., Cani, P. D., Bouter, K. E., Belzer, C., Witjes, J. J., Vrieze, A., de Sonnaville, N., Chaplin, A., van Raalte, D. H., Aalvink, S., Dallinga-Thie, G. M., Heilig, H. G. H. J., Bergström, G., van der Meij, S., van Wagensveld, B. A., Hoekstra, J. B. L. & 6 others, Holleman, F., Stroes, E. S. G., Groen, A. K., Bäckhed, F., de Vos, W. M. & Nieuwdorp, M., 2017, In: PloS one. 12, 11, p. e0181693

    Research output: Contribution to journalJournal articleResearchpeer-review

  102. Published

    Investigating the causal effect of smoking on hay fever and asthma: a Mendelian randomization meta-analysis in the CARTA consortium

    Skaaby, T., Taylor, A. E., Jacobsen, R. K., Paternoster, L., Thuesen, B. H., Ahluwalia, T. S., Larsen, S. C., Zhou, A., Wong, A., Gabrielsen, M. E., Bjørngaard, J. H., Flexeder, C., Männistö, S., Hardy, R., Kuh, D., Barry, S. J., Tang Møllehave, L., Cerqueira, C., Friedrich, N., Bonten, T. N. & 34 others, Noordam, R., Mook-Kanamori, D. O., Taube, C., Jessen, L. E., McConnachie, A., Sattar, N., Upton, M. N., McSharry, C., Bønnelykke, Klaus, Bisgaard, H., Schulz, H., Strauch, K., Meitinger, T., Peters, A., Grallert, H., Nohr, E. A., Kivimaki, M., Kumari, M., Völker, U., Nauck, M., Völzke, H., Power, C., Hyppönen, E., Hansen, Torben, Jørgensen, T., Pedersen, Oluf Borbye, Salomaa, V., Grarup, N., Langhammer, A., Romundstad, P. R., Skorpen, F., Kaprio, J., R Munafò, M. & Linneberg, Allan René, 2017, In: Scientific Reports. 7, 1, 9 p., 2224.

    Research output: Contribution to journalJournal articleResearchpeer-review