- 2018
- Published
Effect of liraglutide treatment on jejunostomy output in patients with short bowel syndrome: An open-label pilot study
Hvistendahl, M., Brandt, C. F., Tribler, S., Naimi, R. M., Hartmann, Bolette, Holst, Jens Juul, Rehfeld, Jens Frederik, Hornum, Mads, Andersen, Jens Rikardt, Henriksen, B. M., Brøbech Mortensen, P. & Jeppesen, Palle Bekker, 2018, In: Journal of Parenteral and Enteral Nutrition. 42, 1, p. 112-121 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of metformin on plasma metabolite profile in the Copenhagen Insulin and Metformin Therapy (CIMT) trial
Safai, N., Suvitaival, T., Ali, A., Spegel, P., Al-Majdoub, M., Carstensen, B., drb459, drb459 & Ridderstråle, M., 2018, In: Diabetic Medicine. 35, 7, p. 944-953Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of Preceding Ethanol Intake on Glucose Response to Low-Dose Glucagon in Individuals With Type 1 Diabetes: A Randomized, Placebo-Controlled, Crossover Study
Ranjan, A., Nørgaard, Kirsten, Tetzschner, R., Steineck, I. I. K., Clausen, T. R., Holst, Jens Juul, Madsbad, Sten & Schmidt, S., 2018, In: Diabetes Care. 41, 4, p. 797-806Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Elucidation of the intrinsic optical properties of hydrogen-bonded and protonated flavin chromophores by photodissociation action spectroscopy
Lincke, K., Langeland, J., Madsen, A. Ø., Kiefer, H. V., Skov, L., Gruber, E., Mikkelsen, Kurt Valentin, Andersen, L. H. & Nielsen, Mogens Brøndsted, 2018, In: Physical Chemistry Chemical Physics. 20, 45, p. 28678-28684 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Endogenous glucagon-like peptide- 1 and 2 are essential for regeneration after acute intestinal injury in mice
Hytting-Andreasen, R., Balk-Møller, E., Hartmann, Bolette, Pedersen, Jens, Windeløv, Johanne Agerlin, Holst, Jens Juul & Kissow, Hannelouise, 2018, In: PLoS ONE. 13, 6, p. 1-14 e0198046.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Endurance training remodels sperm-borne small RNA expression and methylation at neurological gene hotspots
Ingerslev, L. R., Donkin, I., Fabre, O., Versteyhe, S., Mechta, Mie, Pattamaprapanont, P., Mortensen, B., Krarup, N. T. & Barrès, Romain, 2018, In: Clin Epigenetics. 10, 1, p. 1-11 12.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Enterochromaffin 5-HT cells - A major target for GLP-1 and gut microbial metabolites
Lund, M. L., Egerod, Kristoffer Lihme, Engelstoft, M. S., Dmytriyeva, O., Theodorsson, E., Patel, B. A. & Schwartz, Thue W., 2018, In: Molecular Metabolism. 11, p. 70-83 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Enterotypes in the landscape of gut microbial community composition
Costea, P. I., Hildebrand, F., Manimozhiyan, A., Bäckhed, F., Blaser, M. J., Bushman, F. D., De Vos, W. M., Ehrlich, S. D., Fraser, C. M., Hattori, M., Huttenhower, C., Jeffery, I. B., Knights, D., Lewis, J. D., Ley, R. E., Ochman, H., O'Toole, P. W., Quince, C., Relman, D. A., Shanahan, F. & 9 others, , 2018, In: Nature Microbiology. 3, 1, p. 8-16 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Erratum to semaglutide seems to be more effective the other GLP-1Ras
Holst, Jens Juul & Madsbad, Sten, 2018, In: Annals of Translational Medicine. 6, 3, p. 74Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Establishing post mortem criteria for the metabolic syndrome: an autopsy based cross-sectional study
Christensen, M. R., Bugge, A., Malik, M. E., Thomsen, J. L., Lynnerup, Niels, Rungby, Jørgen & Banner, Jytte, 2018, In: Diabetology & Metabolic Syndrome. 10, 1, 8 p., 36.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Estimating the causal effect of body mass index on hay fever, asthma and lung function using Mendelian randomization
Skaaby, T., Taylor, A. E., Thuesen, B. H., Jacobsen, R. K., Friedrich, N., Møllehave, L. T., Hansen, S., Larsen, S. C., Völker, U., Nauck, M., Völzke, H., Hansen, Torben, Pedersen, Oluf Borbye, Jørgensen, T., Paternoster, L., Munafò, M., Grarup, N. & Linneberg, Allan René, 2018, In: Allergy. 73, 1, p. 153-164 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evidence of a liver-alpha cell axis in humans: hepatic insulin resistance attenuates relationship between fasting plasma glucagon and glucagonotropic amino acids
Albrechtsen, Nicolai Jacob Wewer, Færch, K., Jensen, T. M., Witte, D. R., Pedersen, Jens, Mahendran, Y., Jonsson, Anna Elisabet, Galsgaard, Katrine Douglas, Winther-Sørensen, Marie, Torekov, Signe Sørensen, Lauritzen, T., Pedersen, Oluf Borbye, Knop, Filip Krag, Hansen, Torben, Jørgensen, M. E., Vistisen, D. & Holst, Jens Juul, 2018, In: Diabetologia. 61, 3, p. 671-680Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evidence of genetic predisposition for metabolically healthy obesity and metabolically obese normal weight
Huang, L. O., Loos, Ruth & Kilpeläinen, Tuomas O., 2018, In: Physiological Genomics. 50, 3, p. 169-178 10 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Evolutionary conservation of the allosteric activation of factor VIIa by tissue factor in lamprey: comment
Madsen, J. J., Persson, E. & Olsen, O. H., 2018, In: Journal of Thrombosis and Haemostasis. 16, 7, p. 1450-1454Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Exercise increases circulating GDF15 in humans
Kleinert, Maximilian, Clemmensen, Christoffer, Sjøberg, K. A., Carl, Christian Strini, Jeppesen, J. F., Wojtaszewski, Jørgen F P, Kiens, Bente & Richter, Erik A., 2018, In: Molecular Metabolism. 9, p. 187-191 5 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Exercise training alters the genomic response to acute exercise in human adipose tissue
Fabre, O., Ingerslev, L. R., Garde, C., Donkin, I., Simar, D. & Barrès, Romain, 2018, In: Epigenomics. 10, 8, p. 1033-1050 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ExomeChip-Wide Analysis of 95 626 Individuals Identifies 10 Novel Loci Associated With QT and JT Intervals
Bihlmeyer, N. A., Brody, J. A., Smith, A. V., Warren, H. R., Lin, H., Isaacs, A., Liu, C-T., Marten, J., Radmanesh, F., Hall, L. M., Grarup, N., Mei, H., Muller-Nurasyid, M., Huffman, J. E., Verweij, N., Guo, X., Yao, J., Li-Gao, R., van den Berg, M., Weiss, S. & 30 others, , 2018, In: Circulation. Genomic and precision medicine. 11, 1, p. 1-10 e001758.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exploring mucosal function as a clinical endpoint in ulcerative colitis
Kjaergaard, S., Damm, M. M. B., Chang, J., Riis, Lene Buhl, Hytting-Andreasen, R., Krug, S. M., Schulzke, J. D., Bindslev, Niels & Hansen, Morten Bagge, 2018, In: Journal of Crohn's and Colitis. 12, S1, p. S169-S169 P145 .Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Exposure to the gut microbiota drives distinct methylome and transcriptome changes in intestinal epithelial cells during postnatal development
Pan, W., Sommer, F., Falk-Paulsen, M., Ulas, T., Best, P., Fazio, A., Kachroo, P., Luzius, A., Jentzsch, M., Rehman, A., Mueller, F., Lengauer, T., Walter, J., Kuenzel, S., Baines, J. F., Schreiber, S., Franke, A., Schultze, J. L., Backhed, F. & Rosenstiel, P., 2018, In: Genome Medicine. 10, p. 1-15 27.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
FAK tyrosine phosphorylation is regulated by AMPK and controls metabolism in human skeletal muscle
Lassiter, D. G., Nylén, C., Sjögren, R. J. O., Chibalin, A. V., Wallberg-Henriksson, H., Näslund, E., Krook, A. & Zierath, Juleen R, 2018, In: Diabetologia. 61, 2, p. 424-432 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
FGF21, a liver hormone that inhibits alcohol intake in mice, increases in human circulation after acute alcohol ingestion and sustained binge drinking at Oktoberfest
Søberg, S., Andersen, E. S., Dalsgaard, N. B., Jarlhelt, I., Hansen, N. L., Hoffmann, N., Vilsbøll, Tina, Chenchar, A., Jensen, M., Grevengoed, Trisha Jean, Trammell, Sam, Knop, Filip Krag & Gillum, M. P., 2018, In: Molecular Metabolism. 11, p. 96-103 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fasting decreases plasma FGF21 in obese subjects and the expression of FGF21 receptors in adipose tissue in both lean and obese subjects
Nygaard, E. B., Ørskov, Cathrine, Almdal, Thomas Peter, drb459, drb459 & Andersen, B., 2018, In: Journal of Endocrinology. 239, 1, p. 73-80Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps
Mahajan, A., Taliun, D., Thurner, M., Robertson, N. R., Torres, J. M., Rayner, N. W., Payne, A. J., Steinthorsdottir, V., Scott, R. A., Grarup, N., Cook, J. P., Schmidt, E. M., Wuttke, M., Sarnowski, C., Magill, R., Nano, J., Gieger, C., Trompet, S., Lecoeur, C., Preuss, M. H. & 95 others, , 2018, In: Nature Genetics. 50, 11, p. 1505-1513Research output: Contribution to journal › Journal article › Research › peer-review
- Published
First Genome-Wide Association Study of Latent Autoimmune Diabetes in Adults Reveals Novel Insights Linking Immune and Metabolic Diabetes
Cousminer, D. L., Ahlqvist, E., Mishra, R., Andersen, M. K., Chesi, A., Hawa, M. I., Davis, A., Hodge, K. M., Bradfield, J. P., Zhou, K., Guy, V. C., Akerlund, M., Wod, M., Fritsche, L. G., Vestergaard, H., Snyder, J., Højlund, K., Linneberg, A., Karajamaki, A., Brandslund, I. & 33 others, , 2018, In: Diabetes Care. 41, 11, p. 2396-2403Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GSK3 is a negative regulator of the thermogenic program in brown adipocytes
Markussen, L. K., Winther, Sally, Wicksteed, B. & Hansen, Jacob B., 2018, In: Scientific Reports. 8, p. 1-12 3469.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gamma-Aminobutyric Acid Signaling in Brown Adipose Tissue Promotes Systemic Metabolic Derangement in Obesity
Ikegami, R., Shimizu, I., Sato, T., Yoshida, Y., Hayashi, Y., Suda, M., Katsuumi, G., Li, J., Wakasugi, T., Minokoshi, Y., Okamoto, S., Hinoi, E., Nielsen, S., Jespersen, N. Z., Schéele, Camilla Charlotte Nielsen, Soga, T. & Minamino, T., 2018, In: Cell Reports. 24, 11, p. 2827-2837.e5 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals
Lee, J. J., Wedow, R., Okbay, A., Kong, E., Maghzian, O., Zacher, M., Tuan Anh Nguyen-Viet, Bowers, P., Sidorenko, J., Linner, R. K., Fontana, M. A., Kundu, T., Lee, C., Li, H., Li, R., Royer, R., Timshel, P. N., Walters, R. K., Willoughby, E. A., Yengo, L. & 58 others, , 2018, In: Nature Genetics. 50, 8, p. 1112-+Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genes that make you fat, but keep you healthy
Loos, Ruth & Kilpeläinen, Tuomas O., 2018, In: Journal of Internal Medicine. 284, 5, p. 450-463 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic Susceptibility for Childhood BMI has no Impact on Weight Loss Following Lifestyle Intervention in Danish Children
Hollensted, M., Fogh, M., Schnurr, T. M., Kloppenborg, J. T., Have, C. T., Nielsen, T. R. H., Rask, J., Lund, Morten Asp Vonsild, Frithioff-Bøjsøe, C., Østergaard Johansen, M., Vincent Rosenbaum Appel, E., Mahendran, Y., Grarup, N., Kadarmideen, H. N., Pedersen, Oluf Borbye, Holm, Jens-Christian & Hansen, Torben, 2018, In: Obesity. 26, 12, p. 1915-1922 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic and environmental factors affecting birth size variation: a pooled individual-based analysis of secular trends and global geographical differences using 26 twin cohorts
Yokoyama, Y., Jelenkovic, A., Hur, Y-M., Sund, R., Fagnani, C., Stazi, M. A., Brescianini, S., Ji, F., Ning, F., Pang, Z., Knafo-Noam, A., Mankuta, D., Abramson, L., Rebato, E., Hopper, J. L., Cutler, T. L., Saudino, K. J., Nelson, T. L., Whitfield, K. E., Corley, R. P. & 40 others, , 2018, In: International Journal of Epidemiology. 47, 4, p. 1195-1206 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic architecture of obesity and related metabolic traits - recent insights from isolated populations
Lepola, Mette Andersen, Grarup, N., Moltke, Ida, Albrechtsen, Anders & Hansen, Torben, 2018, In: Current Opinion in Genetics and Development. 50, p. 74-78 5 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Genetic aspects of non-alcoholic fatty liver disease (NAFLD)
Stender, S., Grarup, N. & Hansen, Torben, 2018, The Human Gut-Liver-Axis in Health and Disease. Springer, p. 195-206 12 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Genetic determinants of glycated hemoglobin levels in the Greenlandic Inuit population
Appel, V. R., Moltke, Ida, Jørgensen, M. E., Bjerregaard, P., Linneberg, Allan René, Pedersen, Oluf Borbye, Albrechtsen, Anders, Hansen, Torben & Grarup, N., 2018, In: European Journal of Human Genetics. 26, 6, p. 868-875 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic insights into fetal growth and measures of glycaemic regulation and adiposity in adulthood: a family-based study
Hollensted, M., Ekstrøm, Claus Thorn, Pedersen, Oluf Borbye, Eiberg, Hans Rudolf Lytchoff, Hansen, Torben & Gjesing, A. P., 2018, In: BMC Medical Genetics. 19, p. 1-9 9 p., 207.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic predisposition to adiposity is associated with increased objectively assessed sedentary time in young children
Schnurr, T. M., Viitasalo, A., Eloranta, A., Damsgaard, Camilla Trab, Mahendran, Y., Have, C. T., Väistö, J., Hjorth, Mads Fiil, Christensen, L. B., Brage, S., Atalay, M., Lyytikäinen, L., Lindi, V., Lakka, T., Michaelsen, Kim F., Kilpeläinen, Tuomas O. & Hansen, Torben, 2018, In: International Journal of Obesity. 42, 1, p. 111-114 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic risk score of insulin resistance risk variants is associated with increased risk of coronary artery disease in patients referred to coronary angiography
Skals, R. K., Krogager, M. L., Appel, E. V. R., Schnurr, T. M., Have, C. T., Gislason, Gunnar Hilmar, Poulsen, Henrik Enghusen, Køber, Lars Valeur, Engstrøm, Thomas, Stender, S., Hansen, Torben, Grarup, N., Andersson, C., Torp-Pedersen, C. & Weeke, P. E., 2018, In: European Heart Journal. 39, p. 752-753Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic risk scores for body fat distribution attenuate weight loss in women during dietary intervention
Svendstrup, M., Allin, K. H., Sørensen, Thorkild I.A., Hansen, T. H., Grarup, N., Hansen, Torben & drb459, drb459, 2018, In: International Journal of Obesity. 42, 3, p. 370-375 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetics of metabolic traits in Greenlanders: lessons from an isolated population
Lepola, Mette Andersen & Hansen, Torben, 2018, In: Journal of Internal Medicine. 284, 5, p. 464-477 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-Wide Interactions with Dairy Intake for Body Mass Index in Adults of European Descent
Smith, C. E., Follis, J. L., Dashti, H. S., Tanaka, T., Graff, M., Fretts, A. M., Kilpeläinen, T. O., Wojczynski, M. K., Richardson, K., Nalls, M. A., Schulz, C-A., Liu, Y., Frazier-Wood, A. C., van Eekelen, E., Wang, C., de Vries, P. S., Mikkilä, V., Rohde, R., Psaty, B. M., Hansen, T. & 43 others, , 2018, In: Molecular Nutrition & Food Research. 62, 3, p. 1-12 12 p., 1700347.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation
Teumer, A., Chaker, L., Groeneweg, S., Li, Y., Di Munno, C., Barbieri, C., Ahluwalia, Tarun Veer Singh, Astrup, A., Linneberg, Allan René, Pedersen, Oluf Borbye, Sørensen, Thorkild I.A. & ThyroidOmics Consortium, T. C., 2018, In: Nature Communications. 9, 14 p., 4455.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide association analyses identify 39 new susceptibility loci for diverticular disease
Maguire, L. H., Handelman, S. K., Du, X., Chen, Y., Pers, Tune H & Speliotes, E. K., 2018, In: Nature Genetics. 50, 10, p. 1359-1365Research output: Contribution to journal › Letter › Research › peer-review
- Published
Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis
Waage, J., Standl, M., Curtin, J. A., Jessen, L. E., Thorsen, J., Tian, C., Schoettler, N., 23andMe Research Team, AAGC collaborators, Flores, C., Abdellaoui, A., Ahluwalia, T. S., Alves, A. C., Amaral, A. F. S., Antó, J. M., Arnold, A., Barreto-Luis, A., Baurecht, H., van Beijsterveldt, C. E. M., Bleecker, E. R. & 33 others, , 2018, In: Nature Genetics. 50, 8, p. 1072-1080Research output: Contribution to journal › Letter › Research › peer-review
- Published
Genome-wide association study of offspring birth weight in 86 577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics
Beaumont, R. N., Warrington, N. M., Cavadino, A., Tyrrell, J., Nodzenski, M., Horikoshi, M., Geller, F., Myhre, R., Richmond, R. C., Paternoster, L., Bradfield, J. P., Kreiner-Moller, E., Huikari, V., Metrustry, S., Lunetta, K. L., Painter, J. N., Hottenga, J-J., Allard, C., Barton, S. J., Espinosa, A. & 66 others, , 2018, In: Human Molecular Genetics. 27, 4, p. 742-756 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glimepiride monotherapy versus combination of glimepiride and linagliptin therapy in patients with HNF1A-diabetes: a protocol for a randomised, double-blinded, placebo-controlled trial
Christensen, A. S., Storgaard, H., Hædersdal, S., Hansen, Torben, Knop, Filip Krag & Vilsbøll, Tina, 2018, In: BMJ Open. 8, p. 1-9 e022517.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon receptor signaling in metabolic diseases
Albrechtsen, Nicolai Jacob Wewer, 2018, In: Peptides. 100, p. 42-47Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-Like Peptide-1 Inhibits Prandial Gastrointestinal Motility Through Myenteric Neuronal Mechanisms in Humans
Halim, M. A., Degerblad, M., Sundbom, M., Karlbom, U., Holst, Jens Juul, Webb, D. & Hellstrom, P. M., 2018, In: Journal of Clinical Endocrinology & Metabolism. 103, 2, p. 575-585Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide 1 in health and disease
Andersen, A., Lund, A., Knop, Filip Krag & Vilsbøll, Tina, 2018, In: Nature Reviews Endocrinology. 14, p. 390-403Research output: Contribution to journal › Review › Research › peer-review
- Published
Glucagon-like peptide-1 receptor agonists and cardiovascular disease: from LEADER to EXSCEL
Torekov, Signe Sørensen, 2018, In: Cardiovascular Research. 114, 10, p. e70-e71 2 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Glucose Tolerance Tests and Osteocalcin Responses in Healthy People
Starup-Linde, J., Westberg-Rasmussen, S., Lykkeboe, S., Handberg, A., Hartmann, Bolette, Holst, Jens Juul, Hermansen, K., Vestergaard, P. & Gregersen, S., 2018, In: Frontiers in Endocrinology. 9Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Godkendelse af personlig medicin
Sørensen, Thorkild I.A., 2018, In: Ugeskrift for Laeger. 180, p. 1054 1 p., V69798 .Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gut: a key player in the pathogenesis of type 2 diabetes?
Muscogiuri, G., Balercia, G., Barrea, L., Cignarelli, A., Giorgino, F., Holst, Jens Juul, Laudisio, D., Orio, F., Tirabassi, G. & Colao, A., 2018, In: Critical Reviews in Food Science and Nutrition. 58, 8, p. 1294–1309Research output: Contribution to journal › Review › Research › peer-review
- Published
Gut microbiota dysbiosis is associated with malnutrition and reduced plasma amino acid levels: Lessons from genome-scale metabolic modeling
Kumar, M., Ji, B., Babaei, P., Das, P., Lappa, D., Ramakrishnan, G., Fox, T. E., Haque, R., Petri, W. A., Backhed, F. & Nielsen, J., 2018, In: Metabolic Engineering. 49, p. 128-142Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gut microbiota regulates maturation of the adult enteric nervous system via enteric serotonin networks
De Vedder, F., Grasset, E., Holm, L. M., Karsenty, G., Macpherson, A. J., Olofsson, L. E. & Backhed, F., 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 25, p. 6458-6463Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hemodynamic Effects of Glucagon: A Literature Review
Petersen, K. M., Bogevig, S., Holst, Jens Juul, Knop, Filip Krag & Christensen, Mikkel Bring, 2018, In: Journal of Clinical Endocrinology & Metabolism. 103, 5, p. 1804-1812Research output: Contribution to journal › Review › Research › peer-review
- Published
Hepatic NAD+ levels and NAMPT abundance are unaffected during prolonged high-fat diet consumption in C57BL/6JBomTac mice
Dall, M., Penke, M., Sulek, K., Matz-Soja, M., Holst, Birgitte, Garten, A., Kiess, W. & Treebak, Jonas Thue, 2018, In: Molecular and Cellular Endocrinology. 473, p. 245-256 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hepatitis B virus upregulates host microRNAs that target apoptosis-regulatory genes in an in vitro cell model
Nielsen, K. O., Jacobsen, K. S., Mirza, A. H., Winther, T. N., Størling, J., Glebe, D., Pociot, Flemming & Høgh, Birthe, 2018, In: Experimental Cell Research. 371, 1, p. 92-103Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High Blood Eosinophils in Acute Exacerbation of Chronic Obstructive Lung Disease Is Not Associated with Higher Risk of Readmission or Mortality
Jabarkhil, A., Janner, Julie Hjortsø, Moberg, M., Eriksen, N., Pedersen, M. N., Jensen, C. B., Ängquist, Lars, Vestbo, J., Jess, T. & Porsbjerg, Celeste Michala, 2018, In: American Journal of Respiratory and Critical Care Medicine. 197, 1 p., A3123.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Higher chlorzoxazone clearance in obese children compared with nonobese peers
Gade, C., Dalhoff, Kim, Petersen, Tonny Studsgaard, Riis, T., Schmeltz, C., Chabanova, E., Christensen, H. R., Mikus, G., Burhenne, J., Holm, Jens-Christian & Holst, H., 2018, In: British Journal of Clinical Pharmacology. 84, 8, p. 1738-1747 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human P2Y11 expression level affects human P2X7 receptor-mediated cell death
Dreisig, K., Sund, L., Dommer, M. W., Kristensen, N. P., Boddum, K., Viste, R., Fredholm, S., Ødum, Niels, Jäättelä, M., Skov, Søren & Kornum, Birgitte Rahbek, 2018, In: Frontiers in Immunology. 9, JUN, 12 p., 1159.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hyperglucagonemia correlates with plasma levels of non-branched-chain amino acids in patients with liver disease independent of type 2 diabetes
Albrechtsen, Nicolai Jacob Wewer, Junker, A. E., Christensen, M., Hædersdal, S., Wibrand, F., Lund, A. M., Galsgaard, Katrine Douglas, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 2018, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 314, 1, p. G91-G96Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hyperosmolar Duodenal Saline Infusion Lowers Circulating Ghrelin and Stimulates Intestinal Hormone Release in Young Men
Veedfald, Simon, Wu, T., Bound, M., Grivell, J., Hartmann, Bolette, Rehfeld, Jens Frederik, Deacon, Carolyn F., Horowitz, M., Holst, Jens Juul & Rayner, C. K., 2018, In: Journal of Clinical Endocrinology & Metabolism. 103, 12, p. 4409-4418Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hypertension genetic risk score is associated with burden of coronary heart disease among patients referred for coronary angiography
Krogager, M. L., Skals, R. K., Appel, E. V. R., Schnurr, T. M., pjx571, pjx571, Have, C. T., Pedersen, Oluf Borbye, Engstrøm, Thomas, Roden, D. M., Gislason, Gunnar Hilmar, Poulsen, Henrik Enghusen, Køber, Lars Valeur, Stender, Steen, Hansen, Torben, Grarup, N., Andersson, C., Torp-Pedersen, Christian & Weeke, P. E., 2018, In: P L o S One. 13, 12, p. 1-17 e0208645.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of novel LEPR mutations in Pakistani families with morbid childhood obesity
Niazi, R. K., Gjesing, A. P., Hollensted, M., Have, C. T., Grarup, N., Pedersen, Oluf Borbye, Ullah, A., Shahid, G., Ahmad, W., Gul, A. & Hansen, Torben, 2018, In: BMC Medical Genetics. 19, 1, p. 1-8 199.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of protein phosphatase involvement in the AT2 receptor-induced activation of endothelial nitric oxide synthase
Peluso, A., 2018, In: Clinical Science.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of Gut Microbiota and Diet on the Development of Atherosclerosis in Apoe-/- Mice
Jonsson, A. L., Caesar, R., Akrami, R., Reinhardt, C., Hallenius, F. F., Boren, J. & Baeckhed, F., 2018, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 38, 10, p. 2318-2326 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of a vegan diet on the human salivary microbiota
Hansen, T. H., Kern, T., Bak, Emilie Glad, Kashani, A., Allin, K. H., Nielsen, T., Hansen, Torben & Pedersen, Oluf Borbye, 2018, In: Scientific Reports. 8, p. 1-11 5847.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In vitro co-cultures of human gut bacterial species as predicted from co-occurrence network analysis
Das, P., Ji, B., Kovatcheva-Datchary, P., Bäckhed, F. & Nielsen, J., 2018, In: PLOS ONE. 13, 3, p. 1-14 e0195161.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increase in clinically recorded type 2 diabetes after colectomy
Jensen, A. B., Sørensen, Thorkild I.A., Pedersen, Oluf Borbye, Jess, T., Brunak, Søren & Allin, K. H., 2018, In: eLife. 7, e37420.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Incretin responses to oral glucose and mixed meal tests and changes in fasting glucose levels during 7 years of follow-up: The Hoorn Meal Study
Koopman, A. D. M., Rutters, F., Rauh, S. P., Nijpels, G., Holst, Jens Juul, Beulens, J. W., Alssema, M. & Dekker, J. M., 2018, In: PloS one. 13, 1, 13 p., e0191114.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Indicator of RNA oxidation in urine for the prediction of mortality in patients with type 2 diabetes and microalbuminuria: a post-hoc analysis of the Steno-2 trial
Kjær, L. K., Oellgaard, J., Henriksen, T., Gaede, P., Pedersen, Oluf Borbye & Poulsen, Henrik Enghusen, 2018, In: Free Radical Biology and Medicine. 129, p. 247-255Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Individual and combined glucose-lowering effects of glucagon receptor antagonism and dipeptidyl peptidase-4 inhibition
Maagensen, H., Haedersdal, S., Lund, A., Nielsen-Hannerup, E., Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 2018, In: Diabetologia. 61, p. S246-S247Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Inhibiting RHOA Signaling in Mice Increases Glucose Tolerance and Numbers of Enteroendocrine and Other Secretory Cells in the Intestine
Petersen, N., Frimurer, Thomas Michael, Pedersen, M. T., Egerod, Kristoffer Lihme, Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Grapin-Botton, A., Jensen, Kim Bak & Schwartz, Thue W., 2018, In: Gastroenterology. 155, 4, p. 1164-1176 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Insulin Secretion Depends on Intra-islet Glucagon Signaling
Svendsen, B., Larsen, Olav, Gabe, M. B. N., Christiansen, Charlotte Bayer, Rosenkilde, M. M., Drucker, D. J. & Holst, Jens Juul, 2018, In: Cell Reports. 25, 5, p. 1127-1134.E2Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interethnic analyses of blood pressure loci in populations of East Asian and European descent
The International Genomics of Blood Pressure (iGEN-BP) Consortium, T. I. G. O. B. P. (. C., 2018, In: Nature Communications. 9, 5052.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interleukin-6 Delays Gastric Emptying in Humans with Direct Effects on Glycemic Control
Lehrskov, L. L., Lyngbaek, M. P., Soederlund, L., Legaard, G. E., Ehses, J. A., Heywood, S. E., Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Karstoft, K., Pedersen, Bente Klarlund & Ellingsgaard, H., 2018, In: Cell Metabolism. 27, 6, p. 1201-1211Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Is abdominal obesity at baseline influencing weight changes in observational studies and during weight loss interventions?
Svendstrup, M., Allin, K. H., Ängquist, Lars, Schnohr, P., Jensen, G. B., Linneberg, Allan René, Thuesen, B., Astrup, A., Saris, W. H. M., drb459, drb459 & Sørensen, Thorkild I.A., 2018, In: American Journal of Clinical Nutrition. 108, 5, p. 913-921 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
L cell secretory responses after gastric bypass surgery can be imitated in un-operated individuals by modulating carbohydrate digestion
Martinussen, C., Bojsen-Moller, K. N., Dirksen, C., Svane, M. S., Holst, Jens Juul & Madsbad, Sten, 2018, In: Diabetologia. 61, S1, p. S124-S125 244.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Ligand-selective small molecule modulators of the constitutively active vGPCR US28
Amarandi, R., Lückmann, Michael, Melynis, M., Jakobsen, M. H., Fallah, Z., Spiess, Katja, Hjortø, Gertrud Malene, Pui, A., Frimurer, Thomas Michael & Rosenkilde, Mette, 2018, In: European Journal of Medicinal Chemistry. 155, p. 244-254Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Loss-of-function variants in ADCY3 increase risk of obesity and type 2 diabetes
Grarup, N., Moltke, Ida, Lepola, Mette Andersen, Dalby, M., Vitting-Seerup, K., Kern, T. S., Mahendran, Y., Jørsboe, E., Larsen, C. V. L., Dahl-Petersen, I. K., Gilly, A., Suveges, D., Dedoussis, G., Zeggini, E., Pedersen, Oluf Borbye, Andersson, Robin, Bjerregaard, P., Jørgensen, M. E., Albrechtsen, Anders & Hansen, Torben, 2018, In: Nature Genetics. 50, 2, p. 172-174 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Maternal and fetal genetic contribution to gestational weight gain
Warrington, N. M., Richmond, R., Fenstra, B., Myhre, R., Gaillard, R., Paternoster, L., Wang, C. A., Beaumont, R. N., Das, S., Murcia, M., Barton, S. J., Espinosa, A., Thiering, E., Atalay, M., Pitkänen, N., Ntalla, I., Jonsson, A. E., Freathy, R., Karhunen, V., Tiesler, C. M. T. & 44 others, , 2018, In: International journal of obesity (2005). 42, p. 775–784Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Maternal obesity reprograms offspring's executive brain centers in a sex-specific manner? An Editorial for "Perinatal high fat diet and early life methyl donor supplementation alter one carbon metabolism and DNA methylation in the brain" on page 362
Plucinska, Kaja & Barger, S. W., 2018, In: Journal of Neurochemistry. 145, 5, p. 358-361Research output: Contribution to journal › Editorial › Research
- Published
Maternal smoking during pregnancy and offspring overweight: is there a dose-response relationship? An individual patient data meta-analysis
Albers, L., Sobotzki, C., Kuß, O., Ajslev, T., Batista, R. F., Bettiol, H., Brabin, B., Buka, S. L., Cardoso, V. C., Clifton, V. L., Devereux, G., Gilman, S. E., Grzeskowiak, L. E., Heinrich, J., Hummel, S., Jacobsen, G. W., Jones, G., Koshy, G., Morgen, C. S., Oken, E. & 10 others, , 2018, In: International Journal of Obesity. 42, p. 1249-1264 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Maturation of the gut microbiome and risk of asthma in childhood
Stokholm, Jakob, Blaser, M. J., Thorsen, Jonathan Jan Ilve, Rasmussen, Morten Arendt, Waage, J. E., Vinding, R. K., Schoos, A. M., Kunøe, A., Fink, N. R., Chawes, Bo Lund Krogsgaard, Bønnelykke, Klaus, Brejnrod, A. D., Mortensen, M. S., Abu Al-Soud, W., Sørensen, Søren Johannes & Bisgaard, H., 2018, In: Nature Communications. 9, 10 p., 141.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Meta-analysis of exome array data identifies six novel genetic loci for lung function
Jackson, V. E., Latourelle, J. C., Wain, L. V., Smith, A. V., Grove, M. L., Bartz, T. M., Obeidat, M., Province, M. A., Gao, W., Qaiser, B., Porteous, D. J., Cassano, P. A., Ahluwalia, T. S., Grarup, N., Li, J., Altmaier, E., Marten, J., Harris, S. E., Manichaikul, A., Pottinger, T. D. & 31 others, , 2018, In: Wellcome Open Research. 3, p. 1-28Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Metabolic and hepatic effects of liraglutide, obeticholic acid and elafibranor in diet-induced obese mouse models of biopsy-confirmed nonalcoholic steatohepatitis
Tølbøl, K. S., Kristiansen, M. N. B., Hansen, H. H., Veidal, S. S., Rigbolt, K. T. G., Gillum, M. P., Jelsing, J., Vrang, N. & Feigh, M., 2018, In: World Journal of Gastroenterology. 24, 2, p. 179-194 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Metabolite ratios as potential biomarkers for type 2 diabetes: a DIRECT study
Molnos, S., Wahl, S., Haid, M., Eekhoff, E. M. W., Pool, R., Floegel, A., Deelen, J., Much, D., Prehn, C., Breier, M., Draisma, H. H., van Leeuwen, N., Simonis-Bik, A. M. C., Jonsson, A., Willemsen, G., Bernigau, W., Wang-Sattler, R., Suhre, K., Peters, A., Thorand, B. & 24 others, , 2018, In: Diabetologia. 61, 1, p. 117-129 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Metabolomic profiling of maternal hair suggests rapid development of intrahepatic cholestasis of pregnancy
Seymour, J. V. D., Tu, S., He, X., Zhang, H., Han, T., Baker, P. N. & Sulek, K., 2018, In: Metabolomics. 14, 6, p. 1-5 79.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Metformin er en mulig glukagonlignende peptid-1-stimulator
Bahne, E., Brønden, A., Vilsbøll, Tina & Knop, Filip Krag, 2018, In: Ugeskrift for Laeger. 180, 12, 4 p., V07170516.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Metformin-induced glucagon-like peptide-1 secretion contributes to the actions of metformin in type 2 diabetes
Bahne, E., Sun, E. W. L., Young, R. L., Hansen, M., Sonne, D. P., Hansen, J. S., Rohde, U., Liou, A. P., Jackson, M. L., de Fontgalland, D., Rabbitt, P., Hollington, P., Sposato, L., Due, S., Wattchow, D. A., Rehfeld, Jens Frederik, Holst, Jens Juul, Keating, D. J., Vilsbøll, Tina & Knop, Filip Krag, 2018, In: JCI Insight. 3, 23, p. 1-16 e93936.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Methodology for Accurate Detection of Mitochondrial DNA Methylation
Mechta, Mie, Ingerslev, L. R. & Barrès, Romain, 2018, In: Journal of Visualized Experiments. 135, e57772.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Microbial regulation of the L cell transcriptome
Arora, Tulika, Akrami, R., Pais, R., Bergqvist, L., Johansson, B. R., Schwartz, Thue W., Reimann, F., Gribble, F. M. & Bäckhed, F., 2018, In: Scientific Reports. 8, p. 1-9 1207.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Microbially Produced Imidazole Propionate Impairs Insulin Signaling through mTORC1
Koh, A., Molinaro, A., Stahlman, M., Khan, M. T., Schmidt, C., Manneras-Holm, L., Wu, H., Carreras, A., Jeong, H., Olofsson, L. E., Bergh, P., Gerdes, V., Hartstra, A., de Brauw, M., Perkins, R., Nieuwdorp, M., Bergstrom, G. & Backhed, F., 2018, In: Cell. 175, 4, p. 947-961.e17Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular genetic overlap between migraine and major depressive disorder
Yang, Y., Zhao, H., Boomsma, D. I., Ligthart, L., Belin, A. C., Smith, G. D., Esko, T., Freilinger, T. M., Hansen, T. F., Ikram, M. A., Kallela, M., Kubisch, C., Paraskevi, C., Strachan, D. P., Wessman, M., Gormley, P., Anttila, V., Winsvold, B. S., Palta, P., Esko, T. & 30 others, , 2018, In: European Journal of Human Genetics. 26, 8, p. 1202-1216 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mono- and co-activation of the GIP and GLP-1 receptors inhibits bone resorption
Bergmann, N. C., Lund, A., Heimburger, S. M., Gasbjerg, Lærke Smidt, Jørgensen, Niklas Rye, Jessen, L., Hartmann, Bolette, Holst, Jens Juul, Christensen, Mikkel Bring, Vilsbøll, Tina & Knop, Filip Krag, 2018, In: Diabetologia. 61, S.1, p. S348-S348 717.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function
Wyss, A. B., Sofer, T., Lee, M. K., Terzikhan, N., Nguyen, J. N., Lahousse, L., Latourelle, J. C., Smith, A. V., Bartz, T. M., Feitosa, M. F., Gao, W., Ahluwalia, T. S., Tang, W., Oldmeadow, C., Duan, Q., de Jong, K., Wojczynski, M. K., Wang, X-Q., Noordam, R., Hartwig, F. P. & 82 others, , 2018, In: Nature Communications. 9, 15 p., 2976.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
No changes in levels of bone formation and resorption markers following a broad-spectrum antibiotic course
Mikkelsen, K. H., Vilsbøll, Tina, Holst, Jens Juul, Hartmann, Bolette, Knop, Filip Krag & Frost, M., 2018, In: BMC Endocrine Disorders. 18, 6 p., 60.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Non-insulin pharmacological therapies for treating type 1 diabetes
Frandsen, C. S., Dejgaard, T. F., Madsbad, Sten & Holst, Jens Juul, 2018, In: Expert Opinion on Pharmacotherapy. 19, 9, p. 947-960Research output: Contribution to journal › Review › Research › peer-review
- Published
Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries
Feitosa, M. F., Kraja, A. T., Chasman, D. I., Sung, Y. J., Winkler, T. W., Ntalla, I., Guo, X., Franceschini, N., Cheng, C-Y., Sim, X., Vojinovic, D., Marten, J., Musani, S. K., Li, C., Bentley, A. R., Brown, M. R., Schwander, K., Richard, M. A., Noordam, R., Aschard, H. & 31 others, , 2018, In: PLoS ONE. 13, 6, p. 1-36 e0198166.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Older subjects with β-cell dysfunction have an accentuated incretin release
De Jesús Garduno-Garcia, J., Gastaldelli, A., DeFronzo, R. A., Lertwattanarak, R., Holst, Jens Juul & Musi, N., 2018, In: Journal of Clinical Endocrinology and Metabolism. 103, 7, p. 2613-2619 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
One-carbon metabolism markers are associated with cardiometabolic risk factors
Lind, M. V., Lauritzen, Lotte, drb459, drb459, Hansen, Torben, Pedersen, Oluf Borbye, Kristensen, M. B. & Ross, A. B., 2018, In: Nutrition, Metabolism & Cardiovascular Diseases. 28, 4, p. 402-410 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
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Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets
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The isoenzyme pattern of LDH does not play a physiological role; except perhaps during fast transitions in energy metabolism
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