Novo Nordisk Foundation Center for Basic Metabolic Research

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  1. 2019
  2. Published

    Human Paneth cell α-defensin-5 treatment reverses dyslipidemia and improves glucoregulatory capacity in diet-induced obese mice

    Larsen, I. S., Fritzen, Andreas Mæchel, Carl, Christian Strini, Agerholm, M., Damgaard, Mads Vargas, Holm, J. B., Marette, A., Nordkild, P., Kiens, Bente, Kristiansen, Karsten, Wehkamp, J. & Jensen, Benjamin Anderschou Holbech, 2019, In: American Journal of Physiology: Endocrinology and Metabolism. 317, 1, p. E42-E52 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Human brown adipose tissue is phenocopied by classical brown adipose tissue in physiologically humanized mice

    de Jong, J. M. A., Sun, W., Pires, N. D., Frontini, A., Balaz, M., Jespersen, N. Z., Feizi, A., Petrovic, K., Fischer, A. W., Bokhari, M. H., Niemi, T., Nuutila, P., Cinti, S., Nielsen, S., Schéele, Camilla Charlotte Nielsen, Virtanen, K., Cannon, B., Nedergaard, J., Wolfrum, C. & Petrovic, N., 2019, In: Nature Metabolism. 1, p. 830-843

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Human pancreatic islet three-dimensional chromatin architecture provides insights into the genetics of type 2 diabetes

    Miguel-Escalada, I., Bonàs-Guarch, S., Cebola, I., Ponsa-Cobas, J., Mendieta-Esteban, J., Atla, G., Javierre, B. M., Rolando, D. M. Y., Farabella, I., Morgan, C. C., García-Hurtado, J., Beucher, A., Morán, I., Pasquali, L., Ramos-Rodríguez, M., Appel, E. V. R., Linneberg, A., Gjesing, A. P., Witte, D. R., Pedersen, O. & 16 others, Grarup, N., Ravassard, P., Torrents, D., Mercader, J. M., Piemonti, L., Berney, T., de Koning, E. J. P., Kerr-Conte, J., Pattou, F., Fedko, I. O., Groop, L., Prokopenko, I., Hansen, Torben, Marti-Renom, M. A., Fraser, P. & Ferrer, J., 2019, In: Nature Genetics. 51, 7, p. 1137-1148

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Human substance P receptor binding mode of the antagonist drug aprepitant by NMR and crystallography

    Chen, S., Lu, M., Liu, D., Yang, L., Yi, C., Ma, L., Zhang, H., Liu, Q., Frimurer, Thomas Michael, Wang, M., Schwartz, Thue W., Stevens, R. C., Wu, B., Wuthrich, K. & Zhao, Q., 2019, In: Nature Communications. 10, 8 p., 638.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Hvordan får vi evidens for nytten af genomisk medicin for patienten?

    Sørensen, Thorkild I.A., 2019, In: Ugeskrift for Laeger. 181, p. 714-716 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Hybrid Encounters in the arts and sciences. A dialogue

    Arends, B., Arnold, Ken, Greinke, B., Hauser, Jens, Horstmann, N. (ed.) & Landbrecht, C. (ed.), 2019, Berlin: Ernst Schering Foundation. 36 p. (Hybrid Encounters Publication).

    Research output: Book/Report › Book

  8. Published

    Identification of two microRNA nodes as potential cooperative modulators of liver metabolism

    Hochreuter, Mette Yde, Altıntaş, Ali, Garde, C., Emanuelli, Brice, Kahn, C. R., Zierath, Juleen R, Vienberg, S. & Barrès, Romain, 2019, In: Hepatology Research. 49, 12, p. 1451-1465

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Impact of weight-loss management on children and adolescents with obesity and obstructive sleep apnea

    Andersen, I. G., Holm, Jens-Christian & Homøe, Preben, 2019, In: International Journal of Pediatric Otorhinolaryngology. 123, p. 57-62

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Impaired glucose metabolism and altered gut microbiome despite calorie restriction of ob/ob mice

    Kashani, A., Brejnrod, A. D., Jin, C., Kern, T., Madsen, A. N., Holm, L. A., Gerber, G. K., Holm, Jens-Christian, Hansen, Torben, Holst, Birgitte & Arumugam, Mani, 2019, In: Animal Microbiome. 1, 1, 16 p., 11.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Increased Body Weight and Fat Mass After Subchronic GIP Receptor Antagonist, but Not GLP-2 Receptor Antagonist, Administration in Rats

    Baidassano, S., Gasbjerg, Lærke Smidt, Kizilkaya, Hüsün Sheyma, Rosenkilde, Mette, Holst, Jens Juul & Hartmann, Bolette, 2019, In: Frontiers in Endocrinology. 10, 11 p., 492.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Increased frequency of rare missense PPP1R3B variants among Danish patients with type 2 diabetes

    Niazi, R. K., Sun, J., Have, C. T., Hollensted, M., Linneberg, Allan René, Pedersen, Oluf Borbye, Nielsen, J. S., Rungby, Jørgen, Grarup, N., Hansen, Torben & Gjesing, A. P., 2019, In: PLoS ONE. 14, 1, p. 1-12 e0210114.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Increased leptin, decreased adiponectin and FGF21 concentrations in adolescent offspring of women with gestational diabetes

    Kampmann, F. B., Thuesen, Anne Cathrine Baun, Hjort, L., Bjerregaard, A. A., Chavarro, J., Frystyk, J., Bjerre, M., Tetens, Inge , Olsen, S. F., Vaag, A., Damm, Peter & Grunnet, Louise Groth, 2019, In: European Journal of Endocrinology. 181, 6, p. 691-700

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Insulin-Driven PI3K-AKT Signaling in the Hepatocyte Is Mediated by Redundant PI3Kα and PI3Kβ Activities and Is Promoted by RAS

    Molinaro, A., Becattini, B., Mazzoli, A., Bleve, A., Radici, L., Maxvall, I., Sopasakis, V. R., Molinaro, A., Bäckhed, F. & Solinas, G., 2019, In: Cell Metabolism. 29, 6, p. 1400-1409.e5

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Interplay between diet, exercise and the molecular circadian clock in orchestrating metabolic adaptations of adipose tissue

    Dollet, L. & Zierath, Juleen R, 2019, In: Journal of Physiology. 597, 6, p. 1439-1450

    Research output: Contribution to journal › Review › Research › peer-review

  16. Published

    Intestinal Microbiota in Cardiovascular Health and Disease: JACC State-of-the-Art Review

    Tang, W. H. W., Backhed, F., Landmesser, U. & Hazen, S. L., 2019, In: Journal of the American College of Cardiology. 73, 16, p. 2089-2105

    Research output: Contribution to journal › Review › Research › peer-review

  17. Published

    Investigating Intestinal Glucagon after Roux-en-Y Gastric Bypass Surgery

    Jorsal, T., Wewer Albrechtsen, N. J., Christensen, M. M., Mortensen, B., Wandall, E., Langholz, E., Friis, S., Worm, D., Ørskov, C., Støving, R. K., Andries, A., Juhl, C. B., Sørensen, F., Forman, J. L., Falkenhahn, M., Musholt, P. B., Theis, S., Larsen, P. J., Holst, J. J., Vrang, N. & 3 others, Jelsing, J., Vilsbøll, Tina & Knop, Filip Krag, 2019, In: Journal of Clinical Endocrinology and Metabolism. 104, 12, p. 6403–6416 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Iron deficiency among blood donors: experience from the Danish Blood Donor Study and from the Copenhagen ferritin monitoring scheme

    Rigas, A. S., Pedersen, Oluf Borbye, Magnussen, K., Erikstrup, C. & Ullum, H., 2019, In: Transfusion Medicine. 29, S1, p. 23-27

    Research output: Contribution to journal › Review › Research › peer-review

  19. Published

    Joint sequencing of human and pathogen genomes reveals the genetics of pneumococcal meningitis

    Lees, J. A., Ferwerda, B., Kremer, P. H. C., Wheeler, N. E., Seron, M. V., Croucher, N. J., Gladstone, R. A., Bootsma, H. J., Rots, N. Y., Wijmega-Monsuur, A. J., Sanders, E. A. M., Trzcinski, K., Wyllie, A. L., Zwinderman, A. H., van den Berg, L. H., van Rheenen, W., Veldink, J. H., Harboe, Z. B., Lundbo, L. F., de Groot, L. C. P. G. M. & 20 others, van Schoor, N. M., van der Velde, N., Ängquist, Lars, Sørensen, Thorkild I.A., Nohr, E. A., Mentzer, A. J., Mills, T. C., Knight, J. C., du Plessis, M., Nzenze, S., Weiser, J. N., Parkhill, J., Madhi, S., Benfield, Thomas, von Gottberg, A., van der Ende, A., Brouwer, M. C., Barrett, J. C., Bentley, S. D. & van de Beek, D., 2019, In: Nature Communications. 10, 14 p., 2176.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Leptin and Adiponectin as markers for preeclampsia in obese pregnant women, a cohort study

    Thagaard, I. N., Hedley, P. L., Holm, Jens-Christian, Lange, Theis, Larsen, T., Krebs, Lone & Christiansen, M., 2019, In: Pregnancy Hypertension. 15, p. 78-83 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Levels and Changes in Childhood Body Mass Index in Relation to Risk of Atrial Fibrillation and Atrial Flutter in Adulthood

    Adelborg, K., Ängquist, Lars, Ording, A., Gjærde, L. K., Bjerregaard, L. G., Sørensen, H. T., Sørensen, Thorkild I.A. & Baker, J. L., 2019, In: American Journal of Epidemiology. 188, 4, p. 684-693 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Linking glycemic dysregulation in diabetes to symptoms, comorbidities, and genetics through EHR data mining

    Kirk, I. K., Simon, C., Banasik, K., Holm, P. C., Haue, A. D., Jensen, P. B., Jensen, L. J., Rodriguez, C. L., Pedersen, M. K., Eriksson, R., Andersen, H. U., Almdal, T., Bork-Jensen, J., Grarup, N., Borch-Johnsen, K., Pedersen, O., Pociot, F., Hansen, T., Bergholdt, R., Rossing, P. & 1 others, Brunak, Søren, 2019, In: eLife. 8, 19 p., e44941.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Liraglutide improves the beta-cell function without increasing insulin secretion during a mixed meal in patients, who exhibit well-controlled type 2 diabetes and coronary artery disease

    Anholm, C., Kumarathurai, P., Jurs, A., Pedersen, L. R., Nielsen, Olav Wendelboe, Kristiansen, O. P., Fenger, M., Holst, Jens Juul, Madsbad, Sten, Sajadieh, Ahmad & Haugaard, Steen Bendix, 2019, In: Diabetology & Metabolic Syndrome. 11, 12 p., 42.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Liraglutide preserved insulin secretion in adults with newly diagnosed type 1 diabetes: the NewLira trial: [Meeting Abstract}

    Dejgaard, T. F., Frandsen, C., Kielgast, U., Andersen, H. U., Thorsteinsson, B., Krarup, T., Holst, Jens Juul & Madsbad, Sten, 2019, In: Diabetologia. 62, Supl. 1/SI, p. S75-S75 145.

    Research output: Contribution to journal › Conference abstract in journal › Research

  25. Published

    Liraglutide-Induced Weight Loss May be Affected by Autonomic Regulation in Type 1 Diabetes

    Hansen, C. S., Frandsen, C. S., Fleischer, J., Vistisen, D., Holst, Jens Juul, Tarnow, L., Knop, Filip Krag, Madsbad, Sten, Andersen, H. U. & Dejgaard, T. F., 2019, In: Frontiers in Endocrinology. 10, 9 p., 242.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Liver-specific RORα deletion does not affect the metabolic susceptibility to western style diet feeding

    Molinaro, A., Caesar, R., L'homme, L., Koh, A., Stahlman, M., Staels, B. & Backhed, F., 2019, In: Molecular Metabolism. 23, p. 82-87 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Long-Acting Neurotensin Synergizes With Liraglutide to Reverse Obesity Through a Melanocortin-Dependent Pathway

    Ratner, C., He, Z., Grunddal, Kaare Villum, Skov, Louise Julie, Hartmann, Bolette, Zhang, F., Feuchtinger, A., Bjerregaard, Anette, Christoffersen, Christina, Tschöp, M. H., Finan, B., DiMarchi, R. D., Leinninger, G. M., Williams, K. W., Clemmensen, Christoffer & Holst, Birgitte, 2019, In: Diabetes. 68, 6, p. 1329-1340

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Long-acting glucagon-like peptide-1 receptor agonist-status December 2018

    Holst, Jens Juul, 2019, In: Annals of Translational Medicine. 7, 5, 6 p., 83 .

    Research output: Contribution to journal › Editorial › Research

  29. Published

    Longitudinal Associations of Fitness, Motor Competence, and Adiposity with Cognition

    Haapala, E. A., Lintu, N., Vaisto, J., Tompuri, T., Soininen, S., Viitasalo, A., Eloranta, A., Venalainen, T., Saakslahti, A., Laitinen, T. & Lakka, T. A., 2019, In: Medicine and Science in Sports and Exercise. 51, 3, p. 465-471

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Longitudinal associations of physical activity and sedentary time with cardiometabolic risk factors in children

    Väistö, J., Haapala, E. A., Viitasalo, A., Schnurr, T. M., Kilpeläinen, Tuomas O., Karjalainen, P., Westgate, K., Lakka, H., Laaksonen, D. E., Ekelund, U., Brage, S. & Lakka, T. A., 2019, In: Scandinavian Journal of Medicine & Science in Sports. 29, 1, p. 113-123

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    MR-proANP Associated with Body Mass Index in Patients with Anorexia Nervosa

    Goetze, J. P., Gustafsson, Finn, Pedersen, Oluf Borbye & Støving, R. K., 2019, In: The journal of applied laboratory medicine. 4, 1, p. 132-134

    Research output: Contribution to journal › Letter › Research › peer-review

  32. Published

    Major Advances and Discoveries in Diabetes-2019 in Review

    Zierath, Juleen R, 2019, In: Current Diabetes Reports. 19, 11, 9 p., 118.

    Research output: Contribution to journal › Editorial › Research › peer-review

  33. Published

    Management of people with Type 2 diabetes shared between a specialized outpatient clinic and primary health care is noninferior to management in a specialized outpatient clinic: a randomized, noninferiority trial

    Munch, L., Bennich, B. B., Overgaard, D., Konradsen, H., Middelfart, H., Kaarsberg, N., Knop, Filip Krag, Vilsbøll, Tina & Røder, M. E., 2019, In: Diabetic Medicine. 36, 7, p. 854-861

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

    Stokholm, Jakob, Michaelsen, Kim F., Freathy, R. M. & EGG Consortium, E. C., 2019, In: Nature Genetics. 51, 5, p. 804-814

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Maternal body mass index, gestational weight gain, and the risk of overweight and obesity across childhood: An individual participant data meta-analysis

    Voerman, E., Santos, S., Golab, B. P., Amiano, P., Ballester, F., Barros, H., Bergstrom, A., Charles, M-A., Chatzi, L., Chevrier, C., Chrousos, G. P., Corpeleijn, E., Costet, N., Crozier, S., Devereux, G., Eggesbo, M., Ekstrom, S., Fantini, M. P., Farchi, S., Forastiere, F. & 64 others, Georgiu, V., Godfrey, K. M., Gori, D., Grote, V., Hanke, W., Hertz-Picciotto, I., Heude, B., Hryhorczuk, D., Huang, R., Inskip, H., Iszatt, N., Karvonen, A. M., Kenny, L. C., Koletzko, B., Kupers, L. K., Lagstrom, H., Lehmann, I., Magnus, P., Majewska, R., Makela, J., Manios, Y., McAuliffe, F. M., McDonald, S. W., Mehegan, J., Mommers, M., Morgen, C. S., Mori, T. A., Moschonis, G., Murray, D., Chaoimh, C. N., Nohr, E. A., Nybo Andersen, Anne-Marie, Oken, E., Oostvogels, A. J. J. M., Pac, A., Papadopoulou, E., Pekkanen, J., Pizzi, C., Polanska, K., Porta, D., Richiardi, L., Rifas-Shiman, S. L., Ronfani, L., Santos, A. C., Standl, M., Stoltenberg, C., Thiering, E., Thijs, C., Torrent, M., Tough, S. C., Trnovec, T., Turner, S., Van Rossem, L., Von Berg, A., Vrijheid, M., Vrijkotte, T. G. M., West, J., Wijga, A., Wright, J., Zvinchuk, O., Sørensen, Thorkild I.A., Lawlor, D. A., Gaillard, R. & Jaddoe, V. W. V., 2019, In: PLoS Medicine. 16, 2

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Mechanisms Underlying Gut Hormone Secretion Using the Isolated Perfused Rat Small Intestine

    Kuhre, Rune Ehrenreich & Holst, Jens Juul, 2019, In: Journal of Visualized Experiments. 144, e58533.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Mechanisms of action of a carbohydrate-reduced, high-protein diet in reducing the risk of postprandial hypoglycemia after Roux-en-Y gastric bypass surgery

    Kandel, D., Bojsen-Møller, K. N., Svane, M. S., Samkani, A., Astrup, A., Holst, Jens Juul, Madsbad, Sten & Krarup, T., 2019, In: American Journal of Clinical Nutrition. 110, 2, p. 296-304 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Mechanisms preserving insulin action during high dietary fat intake

    Lundsgaard, Anne-Marie, Holm, J. B., Sjøberg, K. A., Bojsen-Møller, K. N., Myrmel, L. S., Fjære, E., Jensen, Benjamin Anderschou Holbech, Nicolaisen, T. S., Hingst, J. R., Hansen, S. L., Doll, S., Geyer, P. E., Deshmukh, Atul Shahaji, Holst, Jens Juul, Madsen, L., Kristiansen, Karsten, Wojtaszewski, Jørgen F P, Richter, Erik A. & Kiens, Bente, 2019, In: Cell Metabolism. 29, 1, p. 50-63, e1-e4 19 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight

    Kupers, L. K., Monnereau, C., Sharp, G. C., Yousefi, P., Salas, L. A., Ghantous, A., Page, C. M., Reese, S. E., Wilcox, A. J., Czamara, D., Starling, A. P., Novoloaca, A., Lent, S., Roy, R., Hoyo, C., Breton, C. V., Allard, C., Just, A. C., Bakulski, K. M., Holloway, J. W. & 107 others, Everson, T. M., Xu, C., Huang, R., van der Plaat, D. A., Wielscher, M., Merid, S. K., Ullemar, V., Rezwan, F. I., Lahti, J., van Dongen, J., Langie, S. A. S., Richardson, T. G., Magnus, M. C., Nohr, E. A., Xu, Z., Duijts, L., Zhao, S., Zhang, W., Plusquin, M., DeMeo, D. L., Solomon, O., Heimovaara, J. H., Jima, D. D., Gao, L., Bustamante, M., Perron, P., Wright, R. O., Hertz-Picciotto, I., Zhang, H., Karagas, M. R., Gehring, U., Marsit, C. J., Beilin, L. J., Vonk, J. M., Jarvelin, M., Bergstrom, A., Ortqvist, A. K., Ewart, S., Villa, P. M., Moore, S. E., Willemsen, G., Standaert, A. R. L., Haberg, S. E., Sørensen, Thorkild I.A., Taylor, J. A., Raikkonen, K., Yang, I. V., Kechris, K., Nawrot, T. S., Silver, M. J., Gong, Y. Y., Richiardi, L., Kogevinas, M., Litonjua, A. A., Eskenazi, B., Huen, K., Mbarek, H., Maguire, R. L., Dwyer, T., Vrijheid, M., Bouchard, L., Baccarelli, A. A., Croen, L. A., Karmaus, W., Anderson, D., de Vries, M., Sebert, S., Kere, J., Karlsson, R., Arshad, S. H., Hamalainen, E., Routledge, M. N., Boomsma, D. I., Feinberg, A. P., Newschaffer, C. J., Govarts, E., Moisse, M., Fallin, M. D., Melen, E., Prentice, A. M., Kajantie, E., Almqvist, C., Oken, E., Dabelea, D., Boezen, H. M., Melton, P. E., Wright, R. J., Koppelman, G. H., Trevisi, L., Hivert, M., Sunyer, J., Munthe-Kaas, M. C., Murphy, S. K., Corpeleijn, E., Wiemels, J., Holland, N., Herceg, Z., Binder, E. B., Smith, G. D., Jaddoe, V. W. V., Lie, R. T., Nystad, W., London, S. J., Lawlor, D. A., Relton, C. L., Snieder, H. & Felix, J. F., 2019, In: Nature Communications. 10, 11 p., 1893.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Meta-analysis of fecal metagenomes reveals global microbial signatures that are specific for colorectal cancer

    Wirbel, J., Pyl, P. T., Kartal, E., Zych, K., Kashani, A., Milanese, A., Fleck, J. S., Voigt, A. Y., Palleja, A., Ponnudurai, R., Sunagawa, S., Coelho, L. P., Schrotz-King, P., Vogtmann, E., Habermann, N., Niméus, E., Thomas, A. M., Manghi, P., Gandini, S., Serrano, D. & 15 others, Mizutani, S., Shiroma, H., Shiba, S., Shibata, T., Yachida, S., Yamada, T., Waldron, L., Naccarati, A., Segata, N., Sinha, R., Ulrich, C. M., Brenner, H., Arumugam, Mani, Bork, P. & Zeller, G., 2019, In: Nature Medicine. 25, 4, p. 679-689 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Metagenomic analysis of colorectal cancer datasets identifies cross-cohort microbial diagnostic signatures and a link with choline degradation

    Thomas, A. M., Manghi, P., Asnicar, F., Pasolli, E., Armanini, F., Zolfo, M., Beghini, F., Manara, S., Karcher, N., Pozzi, C., Gandini, S., Serrano, D., Tarallo, S., Francavilla, A., Gallo, G., Trompetto, M., Ferrero, G., Mizutani, S., Shiroma, H., Shiba, S. & 19 others, Shibata, T., Yachida, S., Yamada, T., Wirbel, J., Schrotz-King, P., Ulrich, C. M., Brenner, H., Arumugam, Mani, Bork, P., Zeller, G., Cordero, F., Dias-Neto, E., Setubal, J. C., Tett, A., Pardini, B., Rescigno, M., Waldron, L., Naccarati, A. & Segata, N., 2019, In: Nature Medicine. 25, 4, p. 667-678 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Metformin-induced changes of the gut microbiota in healthy young men: results of a non-blinded, one-armed intervention study

    Bryrup, T., Thomsen, C. W., Kern, T., Allin, K. H., Brandslund, I., Jørgensen, Niklas Rye, drb459, drb459, Hansen, Torben, Hansen, T. H., Pedersen, Oluf Borbye & Nielsen, T., 2019, In: Diabetologia. 62, 6, p. 1024-1035

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Methods and Guidelines for Measurement of Glucagon in Plasma

    Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2019, In: International Journal of Molecular Sciences (Online). 20, 10 p., 5416.

    Research output: Contribution to journal › Review › Research › peer-review

  44. Published

    Microbial evolutionary medicine: from theory to clinical practice

    Andersen, Sandra Breum, Shapiro, B. J., Vandenbroucke-Grauls, C. & de Vos, M. G. J., 2019, In: Lancet Infectious Diseases. 19, 8, p. e273-e283 11 p.

    Research output: Contribution to journal › Review › Research › peer-review

  45. Published

    Mitochondrial function in liver cells is resistant to perturbations in NAD+ salvage capacity

    Dall, M., Trammell, Sam, Asping, M., Hassing, Anna Skab, Agerholm, M., Vienberg, S. G., Gillum, M. P., Larsen, Steen & Treebak, Jonas Thue, 2019, In: The Journal of Biological Chemistry. 294, 36, p. 13304-13326 23 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Molecular adaptations in human subcutaneous adipose tissue after ten weeks of endurance exercise training in healthy males

    Riis, S., Christensen, B., Nellemann, B., Moller, A. R., Husted, Anna Sofie, Pedersen, S. B., Schwartz, Thue W., Jorgensen, J. O. L. & Jessen, N., 2019, In: Journal of Applied Physiology. 126, 3, p. 569-577

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Motivations for data sharing—views of research participants from four European countries: A DIRECT study

    Shah, N., Coathup, V., Teare, H., Forgie, I., Giordano, G. N., Hansen, T. H., Groeneveld, L., Hudson, M., Pearson, E., Ruetten, H. & Kaye, J., 2019, In: European Journal of Human Genetics. 27, p. 721-729

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Mucosal Metabolomic Profiling and Pathway Analysis Reveal the Metabolic Signature of Ulcerative Colitis

    Diab, J., Hansen, T., Goll, R., Stenlund, H., Jensen, E., Moritz, Thomas, Florholmen, J. & Forsdahl, G., 2019, In: Metabolites. 9, 12, 15 p., 291.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Multi-ancestry Genome-wide Meta-analysis Accounting for Gene-education Interactions in Up to 227,850 Individuals Identifies Several Novel Lipid Loci

    Sung, Y. J., Schwander, K. L., Bentley, A. R., de Vries, P. S., Kilpeläinen, Tuomas O., Noordam, R., Musani, S. K., Aschard, H., de las Fuentes, L. & CHARGE Gene-Lifestyle Interactions, C. G. I., 2019, In: Genetic Epidemiology. 43, 7, p. 912-912 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  50. Published

    Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration

    Noordam, R., Bos, M. M., Wang, H., Winkler, T. W., Bentley, A. R., Kilpeläinen, T. O., de Vries, P. S., Sung, Y. J., Schwander, K., Cade, B. E., Manning, A., Aschard, H., Brown, M. R., Chen, H., Franceschini, N., Musani, S. K., Richard, M., Vojinovic, D., Aslibekyan, S., Bartz, T. M. & 128 others, de Las Fuentes, L., Feitosa, M., Horimoto, A. R., Ilkov, M., Kho, M., Kraja, A., Li, C., Lim, E., Liu, Y., Mook-Kanamori, D. O., Rankinen, T., Tajuddin, S. M., van der Spek, A., Wang, Z., Marten, J., Laville, V., Alver, M., Evangelou, E., Graff, M. E., He, M., Kühnel, B., Lyytikäinen, L., Marques-Vidal, P., Nolte, I. M., Palmer, N. D., Rauramaa, R., Shu, X., Snieder, H., Weiss, S., Wen, W., Yanek, L. R., Adolfo, C., Ballantyne, C., Bielak, L., Biermasz, N. R., Boerwinkle, E., Dimou, N., Eiriksdottir, G., Gao, C., Gharib, S. A., Gottlieb, D. J., Haba-Rubio, J., Harris, T. B., Heikkinen, S., Heinzer, R., Hixson, J. E., Homuth, G., Ikram, M. A., Komulainen, P., Krieger, J. E., Lee, J., Liu, J., Lohman, K. K., Luik, A. I., Mägi, R., Martin, L. W., Meitinger, T., Metspalu, A., Milaneschi, Y., Nalls, M. A., O'Connell, J., Peters, A., Peyser, P., Raitakari, O. T., Reiner, A. P., Rensen, P. C. N., Rice, T. K., Rich, S. S., Roenneberg, T., Rotter, J. I., Schreiner, P. J., Shikany, J., Sidney, S. S., Sims, M., Sitlani, C. M., Sofer, T., Strauch, K., Swertz, M. A., Taylor, K. D., Uitterlinden, A. G., van Duijn, C. M., Völzke, H., Waldenberger, M., Wallance, R. B., van Dijk, K. W., Yu, C., Zonderman, A. B., Becker, D. M., Elliott, P., Esko, T., Gieger, C., Grabe, H. J., Lakka, T. A., Lehtimäki, T., North, K. E., Penninx, B. W. J. H., Vollenweider, P., Wagenknecht, L. E., Wu, T., Xiang, Y., Zheng, W., Arnett, D. K., Bouchard, C., Evans, M. K., Gudnason, V., Kardia, S., Kelly, T. N., Kritchevsky, S. B., Loos, R. J. F., Pereira, A. C., Province, M., Psaty, B. M., Rotimi, C., Zhu, X., Amin, N., Cupples, L. A., Fornage, M., Fox, E. F., Guo, X., Gauderman, W. J., Rice, K., Kooperberg, C., Munroe, P. B., Liu, C., Morrison, A. C., Rao, D. C., van Heemst, D. & Redline, S., 2019, In: Nature Communications. 10, 1, 13 p., 5121.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity

    Kilpeläinen, T. O., Bentley, A. R., Noordam, R., Sung, Y. J., Schwander, K., Winkler, T. W., Jakupović, H., Chasman, D. I., Manning, A., Ntalla, I., Aschard, H., Brown, M. R., de las Fuentes, L., Franceschini, N., Guo, X., Vojinovic, D., Aslibekyan, S., Feitosa, M. F., Kho, M., Musani, S. K. & 32 others, Richard, M., Wang, H., Wang, Z., Bartz, T. M., Bielak, L. F., Campbell, A., Dorajoo, R., Fisher, V., Hartwig, F. P., Horimoto, A. R. V. R., Li, C., Lohman, K. K., Marten, J., Sim, X., Smith, A. V., Tajuddin, S. M., Alver, M., Amini, M., Boissel, M., Chai, J. F., Chen, X., Divers, J., Evangelou, E., Gao, C., Graff, M., Harris, S. E., He, M., Hsu, F. C., Zhao, J. H., Loos, Ruth, LifeLines Cohort Study, L. C. S. & V Varga, Tibor, 2019, In: Nature Communications. 10, 11 p., 376.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions

    de Vries, P. S., Brown, M. R., Bentley, A. R., Sung, Y. J., Winkler, T. W., Ntalla, I., Schwander, K., Kraja, A. T., Guo, X., Franceschini, N., Cheng, C-Y., Sim, X., Vojinovic, D., Huffman, J. E., Musani, S. K., Li, C., Feitosa, M. F., Richard, M. A., Noordam, R., Aschard, H. & 32 others, Bartz, T. M., Bielak, L. F., Deng, X., Dorajoo, R., Lohman, K. K., Manning, A. K., Rankinen, T., Smith, A. V., Tajuddin, S. M., Evangelou, E., Graff, M., Alver, M., Boissel, M., Chai, J. F., Chen, X., Divers, J., Gandin, I., Gao, C., Goel, A., Hagemeijer, Y., Harris, S. E., Hartwig, F. P., He, M., Horimoto, A. R. V. R., Hsu, F., Jackson, A. U., Kasturiratne, A., Komulainen, P., Zhao, J. H., Kilpeläinen, Tuomas O., InterAct Consortium, I. C. & V Varga, Tibor, 2019, In: American Journal of Epidemiology. 188, 6, p. 1033-1054

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    Multiple sclerosis genomic map implicates peripheral immune cells and microglia in susceptibility

    Patsopoulos, N. A., Baranzini, S. E., Santaniello, A., Shoostari, P., Cotsapas, C., Wong, G., Beecham, A. H., James, T., Replogle, J., Vlachos, I. S., McCabe, C., Pers, T. H., Brandes, A., White, C., Keenan, B., Cimpean, M., Winn, P., Panteliadis, I. P., Robbins, A., Andlauer, T. F. M. & 32 others, Zarzycki, O., Dubois, B., Goris, A., Søndergaard, H. B., Sellebjerg, Finn Thorup, Sørensen, Per Soelberg, Ullum, H., Thørner, L. W., Saarela, J., Cournu-Rebeix, I., Damotte, V., Fontaine, B., Guillot-Noel, L., Lathrop, M., Vukusic, S., Berthele, A., Pongratz, V., Buck, D., Gasperi, C., Graetz, C., Grummel, V., Hemmer, B., Hoshi, M., Knier, B., Korn, T., Lill, C. M., Luessi, F., Karpe, F., Lage, K., Oturai, A., International Multiple Sclerosis Genetics Consortium, I. M. S. G. C. & ANZgene, IIBDGC, WTCCC2, A. I. W., 2019, In: Science. 365, 6460, eaav7188.

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    Neuromedin U Does Not Act as a Decretin in Rats

    Kuhre, Rune Ehrenreich, Christiansen, Charlotte Bayer, Ghiasi, S. M., Gabe, M. B. N., Skat-Rørdam, P. A., Modvig, Ida Marie, Mandrup-Poulsen, Thomas, Albrechtsen, Reidar, Rosenkilde, Mette, Hartmann, Bolette, Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, 2019, In: Cell Metabolism. 29, 3, p. 719-726.e1-e5 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  55. Published

    New Avenues in the Regulation of Gallbladder Motility: Implications for the Use of Glucagon-Like Peptide-Derived Drugs

    Gether, I. M., Nexøe-Larsen, C. & Knop, Filip Krag, 2019, In: Journal of Clinical Endocrinology and Metabolism. 104, 7, p. 2463-2472

    Research output: Contribution to journal › Review › Research › peer-review

  56. Published

    No direct effect of SGLT2 activity on glucagon secretion

    Kuhre, Rune Ehrenreich, Ghiasi, S. M., Adriaenssens, A. E., Albrechtsen, Nicolai Jacob Wewer, Andersen, Daniel Bjørklund, Aivazidis, A., Chen, L., Mandrup-Poulsen, Thomas, Ørskov, Cathrine, Gribble, F. M., Reimann, F., Wierup, N., Tyrberg, B. & Holst, Jens Juul, 2019, In: Diabetologia. 62, 6, p. 1011-1023

    Research output: Contribution to journal › Journal article › Research › peer-review

  57. Published

    Non-alcoholic fatty liver disease alters expression of genes governing hepatic nitrogen conversion

    Eriksen, P. L., Vilstrup, H., Rigbolt, K., Suppli, M. P., Sørensen, M., Heebøll, S., Veidal, S. S., Knop, Filip Krag & Thomsen, K. L., 2019, In: Liver International. 39, 11, p. 2094-2101

    Research output: Contribution to journal › Journal article › Research › peer-review

  58. Published

    O12.4. EFFECTS OF THE GLUCAGON-LIKE PEPTIDE-1 RECEPTOR AGONIST EXENATIDE ON BONE STATUS IN OBESE, NON-DIABETIC, ANTIPSYCHOTIC-TREATED SCHIZOPHRENIA SPECTRUM PATIENTS

    Eriksson, R., Broberg, B. V., Ishoy, P. L., Bak, N., Andersen, U. B., Jørgensen, Niklas Rye, Knop, Filip Krag & Ebdrup, Bjørn, 2019, In: Schizophrenia Bulletin. 45, Suppl. 2, p. S198-S199 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research

  59. Published

    Obesity and unfavourable lifestyle increase type 2 diabetes-risk independent of genetic predisposition

    Jakupovic, Hermina, Schnurr, T. M., Carrasquilla, Germán D., Grarup, N., Sørensen, Thorkild I.A., Tjønneland, Anne, Overvad, K., Pedersen, Oluf Borbye, Hansen, Torben & Kilpeläinen, Tuomas O., 2019, In: Diabetologia. 62, Suppl. 1, p. S188 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research

  60. Published

    Obesity-induced CYP2E1 activity in children

    Gade, C., Dalhoff, Kim, Petersen, Tonny Studsgaard, Riis, T., Schmeltz, C., Chabanova, E., Christensen, H. R., Mikus, G., Burhenne, J., Holm, Jens-Christian & Holst, H., 2019, In: British Journal of Clinical Pharmacology. 85, 2, p. 458-459 2 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  61. Published

    Obstructive sleep apnea in children and adolescents with and without obesity

    Andersen, I. G., Holm, Jens-Christian & Homøe, Preben, 2019, In: European Archives of Oto-Rhino-Laryngology. 276, 3, p. 871-878

    Research output: Contribution to journal › Journal article › Research › peer-review

  62. Published

    Osteogenesis depends on commissioning of a network of stem cell transcription factors that act as repressors of adipogenesis

    Rauch, A., Haakonsson, A. K., Madsen, J. G. S., Larsen, M., Forss, I., Madsen, M. R., Van Hauwaert, E. L., Wiwie, C., Jespersen, N. Z., Tencerova, M., Nielsen, R., Larsen, B. D., Roettger, R., Baumbach, J., Schéele, Camilla Charlotte Nielsen, Kassem, M. & Mandrup, S., 2019, In: Nature Genetics. 51, 4, p. 716-727

    Research output: Contribution to journal › Journal article › Research › peer-review

  63. Published

    Overweight Patterns Between Childhood and Early Adulthood and Esophageal and Gastric Cardia Adenocarcinoma Risk

    Petrick, J. L., Jensen, B. W., Sørensen, Thorkild I.A., Cook, M. B. & Baker, J. L., 2019, In: Obesity. 27, 9, p. 1520-1526 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  64. Published

    PAIRUP-MS: Pathway analysis and imputation to relate unknowns in profiles from mass spectrometry-based metabolite data

    Hsu, Y. H., Churchhouse, C., Pers, Tune H, Mercader, J. M., Metspalu, A., Fischer, K., Fortney, K., Morgen, E. K., Gonzalez, C., Gonzalez, M. E., Esko, T. & Hirschhorn, J. N., 2019, In: PLOS Computational Biology. 15, 1, 26 p., e1006734.

    Research output: Contribution to journal › Journal article › Research › peer-review

  65. Published

    Paneth cell α-defensins HD-5 and HD-6 display differential degradation into active antimicrobial fragments

    Ehmann, D., Wendler, J., Koeninger, L., Larsen, I. S., Klag, T., Berger, J., Marette, A., Schaller, M., Stange, E. F., Malek, N. P., Jensen, Benjamin Anderschou Holbech & Wehkamp, J., 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 9, p. 3746-3751

    Research output: Contribution to journal › Journal article › Research › peer-review

  66. Published

    Paracrine Crosstalk between Intestinal L- and D-cells Controls Secretion of Glucagon-Like Peptide-1 in mice

    Jepsen, Sara Lind, Grunddal, Kaare Villum, Albrechtsen, Nicolai Jacob Wewer, Engelstoft, M. S., Gabe, M. B. N., Jensen, E. P., Ørskov, Cathrine, Poulsen, Steen Seier, Rosenkilde, M. M., Pedersen, J., Gribble, F. M., Reimann, F., Deacon, Carolyn F., Schwartz, Thue W., Christ, A. D., Martin, R. E. & Holst, Jens Juul, 2019, In: American Journal of Physiology: Endocrinology and Metabolism. 317, 6, p. E1081-E1093

    Research output: Contribution to journal › Journal article › Research › peer-review

  67. Published

    Parental Education and Genetics of BMI from Infancy to Old Age: A Pooled Analysis of 29 Twin Cohorts

    Silventoinen, K., Jelenkovic, A., Latvala, A., Yokoyama, Y., Sund, R., Sugawara, M., Tanaka, M., Matsumoto, S., Aaltonen, S., Piirtola, M., Freitas, D. L., Maia, J. A., Oncel, S. Y., Aliev, F., Ji, F., Ning, F., Pang, Z., Rebato, E., Saudino, K. J., Cutler, T. L. & 53 others, Hopper, J. L., Ullemar, V., Almqvist, C., Magnusson, P. K. E., Cozen, W., Hwang, A. E., Mack, T. M., Willemsen, G., Bartels, M., van Beijsterveldt, C. E. M., Nelson, T. L., Whitfield, K. E., Sung, J., Kim, J., Lee, J., Lee, S., Llewellyn, C. H., Fisher, A., Medda, E., Nistico, L., Toccaceli, V., Baker, L. A., Tuvblad, C., Corley, R. P., Huibregtse, B. M., Derom, C. A., Vlietinck, R. F., Loos, Ruth, Knafo-Noam, A., Mankuta, D., Abramson, L., Burt, S. A., Klump, K. L., Silberg, J. L., Maes, H. H., Krueger, R. F., McGue, M., Pahlen, S., Gatz, M., Butler, D. A., Harris, J. R., Nilsen, T. S., Harden, K. P., Tucker-Drob, E. M., Franz, C. E., Kremen, W. S., Lyons, M. J., Lichtenstein, P., Jeong, H., Hur, Y., Boomsma, D. I., Sørensen, Thorkild I.A. & Kaprio, J., 2019, In: Obesity. 27, 5, p. 855-865 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  68. Published

    Paternal high-fat diet transgenerationally impacts hepatic immunometabolism

    Barbosa, T. D. C., Alm, P. S., Krook, A., Barrès, Romain & Zierath, Juleen R, 2019, In: FASEB Journal. 33, 5, p. 6269-6280

    Research output: Contribution to journal › Journal article › Research › peer-review

  69. Published

    Patient Assessment of Family Function, Glycemic Control and Quality of Life in Adult Patients With Type 2 Diabetes and Incipient Complications

    Bennich, B. B., Munch, L., Egerod, Ingrid Eugenie, Konradsen, H., Ladelund, S., Knop, Filip Krag, Vilsbøll, Tina, Røder, M. & Overgaard, D., 2019, In: Canadian Journal of Diabetes. 43, 3, p. 193-200

    Research output: Contribution to journal › Journal article › Research › peer-review

  70. Published

    Personality-obesity associations are driven by narrow traits: A meta-analysis

    Vainik, U., Dagher, A., Realo, A., Colodro-Conde, L., Mortensen, Erik Lykke, Jang, K., Juko, A., Kandler, C., Sørensen, Thorkild I.A. & Mottus, R., 2019, In: Obesity Reviews. 20, 8, p. 1121-1131 11 p.

    Research output: Contribution to journal › Review › Research › peer-review

  71. Published

    Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9

    Schmidt, A. F., Holmes, M. V., Preiss, D., Swerdlow, D. I., Denaxas, S., Fatemifar, G., Faraway, R., Finan, C., Valentine, D., Fairhurst-Hunter, Z., Hartwig, F. P., Horta, B. L., Hypponen, E., Power, C., Moldovan, M., Van Iperen, E., Hovingh, K., Demuth, I., Norman, K., Steinhagen-Thiessen, E. & 145 others, Demuth, J., Bertram, L., Lill, C. M., Coassin, S., Willeit, J., Kiechl, S., Willeit, K., Mason, D., Wright, J., Morris, R., Wanamethee, G., Whincup, P., Ben-Shlomo, Y., McLachlan, S., Price, J. F., Kivimaki, M., Welch, C., Sanchez-Galvez, A., Marques-Vidal, P., Nicolaides, A., Panayiotou, A. G., Onland-Moret, N. C., Van Der Schouw, Y. T., Matullo, G., Fiorito, G., Guarrera, S., Sacerdote, C., Wareham, N. J., Langenberg, C., Scott, R. A., Luan, J., Bobak, M., Malyutina, S., Pajak, A., Kubinova, R., Tamosiunas, A., Pikhart, H., Grarup, N., Pedersen, Oluf Borbye, Hansen, Torben, Linneberg, Allan René, Jess, T., Cooper, J., Humphries, S. E., Brilliant, M., Kitchner, T., Hakonarson, H., Carrell, D. S., McCarty, C. A., Lester, K. H., Larson, E. B., Crosslin, D. R., De Andrade, M., Roden, D. M., Denny, J. C., Carty, C., Hancock, S., Attia, J., Holliday, E., Scott, R., Schofield, P., O'Donnell, M., Yusuf, S., Chong, M., Pare, G., Van Der Harst, P., Said, M. A., Eppinga, R. N., Verweij, N., Snieder, H., Christen, T., Mook-Kanamori, D. O., Gustafsson, S., Lind, L., Ingelsson, E., Pazoki, R., Franco, O., Hofman, A., Uitterlinden, A., Dehghan, A., Teumer, A., Baumeister, S., Dörr, M., Lerch, M. M., Völker, U., Völzke, H., Ward, J., Pell, J. P., Meade, T., Christophersen, I. E., Maitland-Van Der Zee, A. H., Baranova, E. V., Young, R., Ford, I., Campbell, A., Padmanabhan, S., Bots, M. L., Grobbee, D. E., Froguel, P., Thuillier, D., Roussel, R., Bonnefond, A., Cariou, B., Smart, M., Bao, Y., Kumari, M., Mahajan, A., Hopewell, J. C., Seshadri, S., Dale, C., Costa, R. P. E., Ridker, P. M., Chasman, D. I., Reiner, A. P., Ritchie, M. D., Lange, L. A., Cornish, A. J., Dobbins, S. E., Hemminki, K., Kinnersley, B., Sanson, M., Labreche, K., Simon, M., Bondy, M., Law, P., Speedy, H., Allan, J., Li, N., Went, M., Weinhold, N., Morgan, G., Sonneveld, P., Nilsson, B., Goldschmidt, H., Sud, A., Engert, A., Hansson, M., Hemingway, H., Asselbergs, F. W., Patel, R. S., Keating, B. J., Sattar, N., Houlston, R., Casas, J. P. & Hingorani, A. D., 2019, In: BMC Cardiovascular Disorders. 19, 1, 10 p., 240.

    Research output: Contribution to journal › Journal article › Research › peer-review

  72. Published

    Physiology of the Incretin Hormones, GIP and GLP-1-Regulation of Release and Posttranslational Modifications

    Holst, Jens Juul, Albrechtsen, Nicolai Jacob Wewer, Rosenkilde, Mette & Deacon, Carolyn F., 2019, In: Comprehensive Physiology. 9, 4, p. 1339-1381

    Research output: Contribution to journal › Journal article › Research › peer-review

  73. Published

    Pirt deficiency has subtle female-specific effects on energy and glucose metabolism in mice

    Jall, S., Finan, B., Collden, G., Fischer, K., Dong, X., Tschoep, M. H., Mueller, T. D. & Clemmensen, Christoffer, 2019, In: Molecular Metabolism. 23, p. 75-81

    Research output: Contribution to journal › Journal article › Research › peer-review

  74. Published

    Plasma FGF-19 Levels are Increased in Patients with Post-Bariatric Hypoglycemia

    Mulla, C. M., Goldfine, A. B., Dreyfuss, J. M., Houten, S., Pan, H., Pober, D. M., Albrechtsen, Nicolai Jacob Wewer, Svane, M. S., Schmidt, J. B., Holst, Jens Juul, Craig, C. M., McLaughlin, T. L. & Patti, M., 2019, In: Obesity Surgery. 29, 7, p. 2092-2099

    Research output: Contribution to journal › Journal article › Research › peer-review

  75. Published

    Plasma proteome profiling discovers novel proteins associated with non-alcoholic fatty liver disease

    Niu, Lili, Geyer, P. E., Albrechtsen, Nicolai Jacob Wewer, Gluud, Lise Lotte, Santos, A., Doll, S., Treit, P. V., Holst, Jens Juul, Knop, Filip Krag, Vilsbøll, Tina, Junker, A., Sachs, S., Stemmer, K., Müller, T. D., Tschöp, M. H., Hofmann, S. M. & Mann, Matthias, 2019, In: Molecular Systems Biology. 15, 16 p., e8793.

    Research output: Contribution to journal › Journal article › Research › peer-review

  76. Published

    Polygenic predisposition to breast cancer and the risk of coronary artery disease

    D'Souza, M., Schou, Morten, Skals, R., Weeke, P. E., Lee, C., Smedegaard, L., Madelaire, C., Gerds, Thomas Alexander, Poulsen, Henrik Enghusen, Hansen, Torben, Grarup, N., Pedersen, Oluf Borbye, Stender, Steen, Engstrøm, Thomas, Fosbøl, E., Nielsen, D., Gislason, Gunnar Hilmar, Køber, Lars Valeur, Torp-Pedersen, C. & Andersson, C., 2019, In: International Journal of Cardiology. 291, p. 145-151 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  77. Published

    Population-based identity-by-descent mapping combined with exome sequencing to detect rare risk variants for schizophrenia

    Harold, D., Connolly, S., Riley, B. P., Kendler, K. S., McCarthy, S. E., McCombie, W. R., Richards, A., Owen, M. J., O'Donovan, M. C., Walters, J., Donnelly, P., Bates, L., Barroso, I., Blackwell, J. M., Bramon, E., Brown, M. A., Casas, J. P., Corvin, A., Deloukas, P., Duncanson, A. & 32 others, Jankowski, J., Markus, H. S., Mathew, C. G., Palmer, C. N. A., Plomin, R., Rautanen, A., Sawcer, S. J., Trembath, R. C., Viswanathan, A. C., Wood, N. W., Spencer, C. C. A., Band, G., Bellenguez, C., Freeman, C., Hellenthal, G., Giannoulatou, E., Hopkins, L., Pirinen, M., Pearson, R., Strange, A., Su, Z., Vukcevic, D., Pers, Tune H, Hansen, M., Hansen, Thomas Folkmann, Li, T., Olsen, L., Pantelis, C., Rasmussen, Henrik Berg, Werge, Thomas, Wellcome Trust Case Control Consortium 2, W. T. C. C. C. 2. & Schizophrenia Working Group of the Psychiatric Genomics Consortium, S. W. G. O. T. P. G. C., 2019, In: American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 180, 3, p. 223-231 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  78. Published

    Postprandial Nutrient Handling and Gastrointestinal Hormone Secretion After Roux-en-Y Gastric Bypass vs Sleeve Gastrectomy

    Svane, M. S., Bojsen-Moller, K. N., Martinussen, C., Dirksen, C., Madsen, J. L., Reitelseder, S., Holm, L., Rehfeld, Jens Frederik, Kristiansen, V. B., van Hall, Gerrit, Holst, Jens Juul & Madsbad, Sten, 2019, In: Gastroenterology. 156, 6, p. 1627-1641

    Research output: Contribution to journal › Journal article › Research › peer-review

  79. Published

    Postprandial hypoglycaemia after Roux-en-Y gastric bypass and the effects of acarbose, sitagliptin, verapamil, liraglutide and pasireotide

    Ohrstrom, C. C., Worm, Dorte, Hojager, A., Andersen, D., Holst, Jens Juul, Kielgast, U. L. & Hansen, D. L., 2019, In: Diabetes, Obesity and Metabolism. 21, 9, p. 2142-2151

    Research output: Contribution to journal › Journal article › Research › peer-review

  80. Published

    Postprandial levels of GLP-1, GIP and glucagon after 2 years of weight loss with a Paleolithic diet: a randomised controlled trial in healthy obese women

    Otten, J., Ryberg, M., Mellberg, C., Andersson, T., Chorell, E., Lindahl, B., Larsson, C., Holst, Jens Juul & Olsson, T., 2019, In: European Journal of Endocrinology. 180, 6, p. 417-427

    Research output: Contribution to journal › Journal article › Research › peer-review

  81. Published

    Pre-meal and postprandial lipaemia in subjects with the metabolic syndrome: effects of timing and protein quality (randomised crossover trial)

    Bjørnshave, A., Johansen, T. N., Amer, B., Dalsgaard, T. K., Holst, Jens Juul & Hermansen, K., 2019, In: British Journal of Nutrition. 121, 3, p. 312-321

    Research output: Contribution to journal › Journal article › Research › peer-review

  82. Published

    Preadipocytes from obese humans with type 2 diabetes are epigenetically reprogrammed at genes controlling adipose tissue function

    Andersen, E., Ingerslev, L. R., Fabre, O., Donkin, I., Altıntaş, Ali, Versteyhe, S., Bisgaard, T., Kristiansen, V. B., Simar, D. & Barrès, Romain, 2019, In: International Journal of Obesity. 43, 2, p. 306-318 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  83. Published

    Preassociation between the 5-HT7 serotonin receptor and G protein Gs: molecular determinants and association with low potency activation of adenylyl cyclase

    Ulsund, A. H., Dahl, M., Frimurer, Thomas Michael, Manfra, O., Schwartz, Thue W., Levy, F. O. & Andressen, K. W., 2019, In: FASEB Journal. 33, 3, p. 3870-3886

    Research output: Contribution to journal › Journal article › Research › peer-review

  84. Published

    Prenatal Exposure to Acetaminophen and Overweight in Childhood

    Liew, Z., Nohr, E. A., Morgen, C. S., Ernst, A., Li, J., Sørensen, Thorkild I.A. & Olsen, J., 2019, In: Obesity. 27, 8, p. 1314-1322 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  85. Published

    Preserved glucose response to low-dose glucagon after exercise in insulin-pump-treated individuals with type 1 diabetes: a randomised crossover study

    Steineck, I. I. K., Ranjan, A., Schmidt, S., Clausen, T. R., Holst, Jens Juul & Nørgaard, Kirsten, 2019, In: Diabetologia. 62, 4, p. 582-592

    Research output: Contribution to journal › Journal article › Research › peer-review

  86. Published

    Prevalence of patients with self‐reported hidradenitis suppurativa in a cohort of Danish blood donors: a cross‐sectional study

    Riis, P. T., Pedersen, O. B., Sigsgaard, V., Erikstrup, C., Paarup, H. M., Nielsen, K. R., Burgdorf, K. S., Hjalgrim, H., Rostgaard, K., Banasik, Karina, Ullum, H. & Jemec, Gregor, 2019, In: British Journal of Dermatology. 180, 4, p. 774-781

    Research output: Contribution to journal › Journal article › Research › peer-review

  87. Published

    Production of stellate cells from induced pluripotent stem cells to study Alzheimer's disease pathology

    Mogus, L., Bergmann, T. B., Liu, Y., Lee, J., Pfisterer, U. G., Handfield, L., Asenjo Martinez, A., Seemann, Ernst Stefan, Witter, M., Khodosevich, Konstantin, Gorodkin, Jan, Hemberg, M., Pers, Tune H & Hall, Vanessa Jane, 2019. 1 p.

    Research output: Contribution to conference › Conference abstract for conference › Communication

  88. Published

    Pros and cons of Roux en-Y gastric bypass surgery in obese patients with type 2 diabetes

    Justinussen, T., Madsbad, Sten, Holst, Jens Juul & Bojsen-Moller, K. N., 2019, In: Expert Review of Endocrinology & Metabolism. 14, 4, p. 243-257

    Research output: Contribution to journal › Review › Research › peer-review

  89. Published

    Protein aggregation capture on microparticles enables multi-purpose proteomics sample preparation

    Batth, Tanveer Singh, Tollenaere, M. A. X., Rüther, P. L., Gonzalez-Franquesa, A., Prabhakar, B. S., Bekker-Jensen, Simon Holst, Deshmukh, Atul Shahaji & Olsen, Jesper Velgaard, 2019, In: Molecular and Cellular Proteomics. 18, 5, p. 1027-1035

    Research output: Contribution to journal › Journal article › Research › peer-review

  90. Published

    Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution

    Justice, A. E., Karaderi, T., Highland, H. M., Young, K. L., Graff, M., Lu, Y., Turcot, V., Auer, P. L., Fine, R. S., Guo, X., Schurmann, C., Lempradl, A., Marouli, E., Mahajan, A., Winkler, T. W., Locke, A. E., Medina-Gomez, C., Esko, T., Vedantam, S., Giri, A. & 31 others, Lo, K. S., Alfred, T., Mudgal, P., Ng, M. C. Y., Heard-Costa, N. L., Feitosa, M. F., Manning, A. K., Willems, S. M., Sivapalaratnam, S., Abecasis, G., Alam, D. S., Allison, M., Amouyel, P., Arzumanyan, Z., Balkau, B., Bork-Jensen, J., Grarup, N., Hansen, Torben, Jørgensen, T., Justesen, Johanne Marie, Karpe, F., Kovacs, P., Li, J., Lind, L., Linneberg, Allan René, Pedersen, Oluf Borbye, Pers, Tune H, drb459, drb459, Zhao, J. H., Loos, R. J. F. & CHD Exome+ Consortium, C. E. C., 2019, In: Nature Genetics. 51, 3, p. 452-469 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  91. Published

    Proteomics-Based Comparative Mapping of the Secretomes of Human Brown and White Adipocytes Reveals EPDR1 as a Novel Batokine

    Deshmukh, A. S., Peijs, L., Beaudry, J. L., Jespersen, N. Z., Nielsen, C. H., Ma, T., Brunner, A. D., Larsen, T. J., Bayarri-Olmos, R., Prabhakar, B. S., Helgstrand, C., Severinsen, M. C. K., Holst, B., Kjaer, A., Tang-Christensen, M., Sanfridson, A., Garred, P., Privé, G. G., Pedersen, B. K., Gerhart-Hines, Z. & 4 others, Nielsen, S., Drucker, D. J., Mann, Matthias & Schéele, Camilla Charlotte Nielsen, 2019, In: Cell Metabolism. 30, 5, p. 963-975.e7 21 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  92. Published

    Protocol for a randomised controlled trial of the combined effects of the GLP-1 receptor agonist liraglutide and exercise on maintenance of weight loss and health after a very low-calorie diet

    Jensen, Simon Birk Kjær, Lundgren, J. R., Janus, C., Juhl, C. R., Olsen, L. M., Rosenkilde, M., Holst, Jens Juul, Stallknecht, Bente Merete, Madsbad, Sten & Torekov, Signe Sørensen, 2019, In: BMJ Open. 9, 11, 10 p., e031431.

    Research output: Contribution to journal › Journal article › Research › peer-review

  93. Published

    Quality of dietary fat and genetic risk of type 2 diabetes: individual participant data meta-analysis

    Merino, J., Guasch-Ferré, M., Ellervik, C., Dashti, H. S., Sharp, S. J., Wu, P., Overvad, K., Sarnowski, C., Kuokkanen, M., Lemaitre, R. N., Justice, A. E., Ericson, U., Braun, K. V. E., Mahendran, Y., Frazier-Wood, A. C., Sun, D., Chu, A. Y., Tanaka, T., Luan, J., Hong, J. & 48 others, Tjønneland, Anne, Ding, M., Lundqvist, A., Mukamal, K., Rohde, R., Schulz, C., Franco, O. H., Grarup, N., Chen, Y. I., Bazzano, L., Franks, P. W., Buring, J. E., Langenberg, C., Liu, C., Hansen, Torben, Jensen, Majken Karoline, Sääksjärvi, K., Psaty, B. M., Young, K. L., Hindy, G., Sandholt, C. H., Ridker, P. M., Ordovas, J. M., Meigs, J. B., Pedersen, Oluf Borbye, Kraft, P., Perola, M., North, K. E., Orho-Melander, M., Voortman, T., Toft, Ulla Marie Nørgaard, Rotter, J. I., Qi, L., Forouhi, N. G., Mozaffarian, D., Sørensen, Thorkild I.A., Stampfer, M. J., Männistö, S., Selvin, E., Imamura, F., Salomaa, V., Hu, F. B., Wareham, N. J., Dupuis, J., Smith, C. E., Kilpeläinen, Tuomas O., Chasman, D. I. & Florez, J. C., 2019, In: BMJ (Clinical research ed.). 366, p. l4292

    Research output: Contribution to journal › Journal article › Research › peer-review

  94. Published

    Quantitative proteomics and single-nucleus transcriptomics of the sinus node elucidates the foundation of cardiac pacemaking

    Linscheid, N., Logantha, S. J. R. J., Poulsen, C., Zhang, S., Schrölkamp, Maren, Egerod, Kristoffer Lihme, Thompson, J. J., Kitmitto, A., Galli, G., Humphries, M. J., Zhang, H., Pers, Tune H, Olsen, Jesper Velgaard, Boyett, M. & Lundby, Alicia, 2019, In: Nature Communications. 10, 19 p., 2889.

    Research output: Contribution to journal › Journal article › Research › peer-review

  95. Published

    RETRACTION: Glucose-Dependent Insulinotropic Polypeptide Increases Blood Flow in Adipose Tissue of Humans by Recruiting Capillaries (Retraction of Vol 104, Pg 16, 2019)

    Asmar, M., Asmar, A., Simonsen, L., Holst, Jens Juul & Bulow, J., 2019, In: Journal of Clinical Endocrinology & Metabolism. 104, 1, p. W1-W9

    Research output: Contribution to journal › Journal article › Research › peer-review

  96. Published

    Reappraisal of variants previously linked with sudden infant death syndrome: results from three population-based cohorts

    Paludan-Müller, Christian, Ghouse, Jonas, Vad, O. B., Herfelt, C. B., Lundegaard, Pia Rengtved, Ahlberg, G., Schmitt, Nicole, Svendsen, Jesper Hastrup, Haunsø, Stig, Bundgård, Henning, Hansen, Torben, Kanters, Jørgen K. & Olesen, Morten Steen Salling, 2019, In: European Journal of Human Genetics. 27, 9, p. 1427-1435

    Research output: Contribution to journal › Journal article › Research › peer-review

  97. Published

    Reference values for fasting serum concentrations of thyroid-stimulating hormone and thyroid hormones in healthy Danish/North-European white children and adolescents

    Gunapalasingham, G., Frithioff-Bojsoe, C., Lund, Morten Asp Vonsild, Hedley, P. L., Fonvig, Cilius Esmann, Dahl, M., Pedersen, Oluf Borbye, Christiansen, M., Hansen, Torben, Lausten-Thomsen, U. & Holm, Jens-Christian, 2019, In: Scandinavian Journal of Clinical & Laboratory Investigation. 79, 1-2, p. 129-135

    Research output: Contribution to journal › Journal article › Research › peer-review

  98. Published

    Reference values for leptin/adiponectin ratio in healthy children and adolescents

    Lausten-Thomsen, U., Lund, Morten Asp Vonsild, Frithioff-Bojsoe, C., Hedley, P. L., Pedersen, Oluf Borbye, Hansen, Torben, Christiansen, M. & Holm, Jens-Christian, 2019, In: Clinica Chimica Acta. 493, p. 123-128

    Research output: Contribution to journal › Journal article › Research › peer-review

  99. Published

    Regulation of glucose uptake and inflammation markers by FOXO1 and FOXO3 in skeletal muscle

    Lundell, L. S., Massart, J., Altıntaş, Ali, Krook, A. & Zierath, Juleen R, 2019, In: Molecular Metabolism. 20, p. 79-88 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  100. Published

    Remission of Bile Acid Malabsorption Symptoms Following Treatment With the Glucagon-Like Peptide 1 Receptor Agonist Liraglutide

    Kårhus, M. L., Brønden, A., Roder, M. E., Leotta, S., Sonnet, D. P. & Knop, Filip Krag, 2019, In: Gastroenterology. 157, 2, p. 569-571

    Research output: Contribution to journal › Journal article › Research › peer-review

  101. Published

    Remitted affective disorders and high familial risk of affective disorders associate with aberrant intestinal microbiota

    Vinberg, Maj, Ottesen, N. M., Meluken, I., Sørensen, N., Pedersen, Oluf Borbye, Kessing, Lars Vedel & Miskowiak, Kamilla, 2019, In: Acta Psychiatrica Scandinavica. 139, 2, p. 174-184 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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