- 2019
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Reproducible, interactive, scalable and extensible microbiome data science using QIIME 2
Bolyen, E., Rideout, J. R., Dillon, M. R., Bokulich, N., Abnet, C. C., Al-Ghalith, G. A., Alexander, H., Alm, E. J., Arumugam, M., Asnicar, F., Bai, Y., Bisanz, J. E., Bittinger, K., Brejnrod, A., Brislawn, C. J., Brown, C. T., Callahan, B. J., Caraballo-Rodriguez, A. M., Chase, J., Cope, E. K. & 92 others, , 2019, In: Nature Biotechnology. 37, 8, p. 852-857Research output: Contribution to journal › Letter › Research › peer-review
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Revisiting How the Brain Senses Glucose-And Why
Bentsen, M. A., Mirzadeh, Z. & Schwartz, M. W., 2019, In: Cell Metabolism. 29, 1, p. 11-17Research output: Contribution to journal › Review › Research › peer-review
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Rfx6 promotes the differentiation of peptide-secreting enteroendocrine cells while repressing genetic programs controlling serotonin production
Piccand, J., Vagne, C., Blot, F., Meunier, A., Beucher, A., Strasser, P., Lund, M. L., Ghimire, S., Nivlet, L., Lapp, C., Petersen, N., Engelstoft, M. S., Thibault-Carpentier, C., Keime, C., Correa, S. J., Schreiber, V., Molina, N., Schwartz, Thue W., De Arcangelis, A. & Gradwohl, G., 2019, In: Molecular Metabolism. 29, p. 24-39Research output: Contribution to journal › Journal article › Research › peer-review
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RhoA in tyrosine hydroxylase neurons regulates food intake and body weight via altered sensitivity to peripheral hormones
Skov, Louise Julie, Ratner, C., Hansen, Nikolaj Winther, Thompson, J. J., Egerod, Kristoffer Lihme, Burm, Hayley Beth, Dalbøge, L. S., Hedegaard, M. A., Brakebusch, Cord Herbert, Pers, Tune H, Perrier, Jean-Francois Marie & Holst, Birgitte, 2019, In: Journal of Neuroendocrinology. 31, 7, 13 p., UNSP e12761.Research output: Contribution to journal › Conference article › Research › peer-review
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Rising rural body-mass index is the main driver of the global obesity epidemic in adults
Ängquist, Lars, Baker, J. L., Damsgaard, Camilla Trab, Eliasen, M., Linneberg, Allan René, Michaelsen, Kim F., Molbo, Drude, Mortensen, Erik Lykke, Sørensen, Thorkild I.A., Jørgensen, T., Tang Møllehave, L., Thuesen, B. H., Osler, Merete & NCD Risk Factor Collaboration (NCD-RisC), N. R. F. C., 2019, In: Nature. 569, 7755, p. 260-264 5 p.Research output: Contribution to journal › Letter › Research › peer-review
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Role of Diacylglycerol Kinases in Glucose and Energy Homeostasis
Massart, J. & Zierath, Juleen R, 2019, In: Trends in Endocrinology and Metabolism. 30, 9, p. 603-617Research output: Contribution to journal › Review › Research › peer-review
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Sacubitril/Valsartan Augments Postprandial Plasma Concentrations of Active GLP-1 When Combined With Sitagliptin in Men
Albrechtsen, Nicolai Jacob Wewer, Mark, P. D., Terzic, D., Hansen, L. H., Andersen, U. Ø., Hartmann, Bolette, Carr, R. D., Gustafsson, Finn, Deacon, Carolyn F., Holst, Jens Juul, Goetze, Jens P. & Plomgaard, Peter Stendahl, 2019, In: Journal of Clinical Endocrinology and Metabolism. 104, 9, p. 3868-3876Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sandwich cortial lamination and single-cell analysis decodes the developing spatial processing system
Liu, Y., Bergmann, T. B., Lee, J., Pfisterer, U. G., Handfield, L-F., Mori, Y., Asenjo Martinez, A., Lisa Vargas, I., Seemann, E. S., Lee, J. T. H., Patikis, N., Peralvo Vidal, J. M., Pihl, M., Kornum, B. R., Thomsen, P. D., Hyttel, P., Witter, M., Khodosevich, K., Gorodkin, J., Hemberg, M. & 2 others, , 2019. 45 p.Research output: Contribution to conference › Paper › Communication
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Screening of 31 genes involved in monogenic forms of obesity in 23 Pakistani probands with early-onset childhood obesity: a case report
Niazi, R. K., Gjesing, A. P., Hollensted, M., Have, C. T., Borisevich, D., Grarup, N., Pedersen, Oluf Borbye, Ullah, A., Shahid, G., Shafqat, I., Gul, A. & Hansen, Torben, 2019, In: B M C Medical Genetics. 20, 8 p., 152.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Selective Allosteric Modulation of N-Terminally Cleaved, but Not Full Length CCL3 in CCR1
Larsen, Olav, Lückmann, Michael, van der Velden, W. J. C., Oliva-Santiago, M., Brvar, M., Ulven, Trond, Frimurer, Thomas Michael, Karlshøj, S. & Rosenkilde, Mette, 2019, In: ACS Pharmacology & Translational Science. 2, 6, p. 429-441 13 p.Research output: Contribution to journal › Letter › Research › peer-review
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Separate and Combined Glucometabolic Effects of Endogenous Glucose-Dependent Insulinotropic Polypeptide and Glucagon-like Peptide 1 in Healthy Individuals
Gasbjerg, Lærke Smidt, Helsted, M. M., Hartmann, Bolette, Jensen, M. H., Gabe, M. B. N., wbf943, wbf943, Veedfald, Simon, Stensen, S., Lanng, A. R., Bergmann, N. C., Christensen, Mikkel Bring, Vilsbøll, Tina, Holst, Jens Juul, Rosenkilde, Mette & Knop, Filip Krag, 2019, In: Diabetes. 68, 3, p. 906-917Research output: Contribution to journal › Journal article › Research › peer-review
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Sequencing reveals protective and pathogenic effects on development of diabetes of rare GLIS3 variants
Sun, J., Have, C. T., Hollensted, M., Grarup, N., Linneberg, Allan René, Pedersen, Oluf Borbye, Nielsen, J. S., Rungby, Jørgen, Christensen, C., Brandslund, I., Kristiansen, Karsten, Jun, W., Hansen, Torben & Gjesing, A. P., 2019, In: PLoS ONE. 14, 8, 10 p., e0220805.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sex influences DNA methylation and gene expression in human skeletal muscle myoblasts and myotubes
Davegardh, C., Wedin, E. H., Broholm, C., Henriksen, T. I., Pedersen, M., Pedersen, Bente Klarlund, Schéele, Camilla Charlotte Nielsen & Ling, C., 2019, In: Stem Cell Research & Therapy. 10Research output: Contribution to journal › Journal article › Research › peer-review
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Sharing data for future research - engaging participants' views about data governance beyond the original project: a DIRECT Study
Shah, N., Coathup, V., Teare, H., Forgie, I., Giordano, G. N., Hansen, T. H., Groeneveld, L., Hudson, M., Pearson, E., Ruetten, H. & Kaye, J., 2019, In: Genetics In Medicine. 21, p. 1131-1138 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Shining light on microbial signaling to distant organs
Backhed, F., 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 16, p. 7617-7619Research output: Contribution to journal › Comment/debate › Research
- Published
Short-chain fatty acids and regulation of pancreatic endocrine secretion in mice
Ørgaard, A., Jepsen, Sara Lind & Holst, Jens Juul, 2019, In: Islets. 11, 5, p. 103-111Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Short‐chain fatty acids and gut microbiota in multiple sclerosis
Melbye, P., Olsson, A., Hansen, T. H., Søndergaard, H. B. & Oturai, A. B., 2019, In: Acta Neurologica Scandinavica. 139, 3, p. 208-219Research output: Contribution to journal › Review › Research › peer-review
- Published
Simplified Intestinal Microbiota to Study Microbe-Diet-Host Interactions in a Mouse Model
Kovatcheva-Datchary, P., Shoaie, S., Lee, S., Wahlstrom, A., Nookaew, I., Hallen, A., Perkins, R., Nielsen, J. & Bäckhed, F., 2019, In: Cell Reports. 26, 13, p. 3772-3783.e6 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Smallpox and BCG vaccination in childhood and cutaneous malignant melanoma in Danish adults followed from 18 to 49 years
Rieckmann, Andreas, Meyle, K. D., Rod, Naja Hulvej, Baker, J. L., Benn, C. S., Aaby, P. & Sørup, S., 2019, In: Vaccine. 37, 44, p. 6730-6736 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Substrate metabolism, hormone and cytokine levels and adipose tissue signalling in individuals with type 1 diabetes after insulin withdrawal and subsequent insulin therapy to model the initiating steps of ketoacidosis
Voss, T. S., Vendelbo, M. H., Kampmann, U., Pedersen, S. B., Nielsen, Thomas Svava, Johannsen, M., Svart, M. V., Jessen, N. & Møller, N., 2019, In: Diabetologia. 62, 3, p. 494-503Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sustained Improvements in Glucose Metabolism Late After Roux-En-Y Gastric Bypass Surgery in Patients with and Without Preoperative Diabetes
Jørgensen, N. B., Bojsen-Møller, K. N., Dirksen, C., Martinussen, C., Svane, M. S., Kristiansen, V. B., Holst, Jens Juul & Madsbad, Sten, 2019, In: Scientific Reports. 9, 1, 10 p., 15154.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
THU-491-The role of alanine glyoxylate aminotransferase in hepatocellular carcinoma
Satriano, L., Lewinska, Monika, Rourke, C. O., Oliveira, D. V., Bhatt, D. K., Taranta, A., Herr, M., Straub, B., Conner, D. E. A., Budhu, D. A., Pomyen, Y., Ma, Tao, Gerhart-Hines, Zach, Stjernegaard, D. C. S., Matter, M., Crocoll, D. C., Wang, X. W., Marquardt, J. & Andersen, Jesper Bøje, 2019, p. e377.Research output: Contribution to conference › Poster › Research
- Published
The Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia: design, results and future prospects
Middeldorp, C. M., Mahajan, A., Horikoshi, M., Robertson, N. R., Beaumont, R. N., Bradfield, J. P., Bustamante, M., Cousminer, D. L., Day, F. R., De Silva, N. M., Guxens, M., Mook-Kanamori, D. O., St Pourcain, B., Warrington, N. M., Adair, L. S., Ahlqvist, E., Ahluwalia, T. S., Almgren, P., Ang, W., Atalay, M. & 463 others, , 2019, In: European Journal of Epidemiology. 34, 3, p. 279-300 22 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Molecular Diversity of Vagal Afferents Revealed
Egerod, Kristoffer Lihme, Schwartz, Thue W. & Gautron, L., 2019, In: Trends in Neurosciences. 42, 10, p. 663-666Research output: Contribution to journal › Editorial › Research › peer-review
- Published
The Promise of Selecting Individuals from the Extremes of Exposure in the Analysis of Gene-Physical Activity Interactions
Osazuwa-Peters, O. L., Schwander, K., Waken, R. J., de Las Fuentes, L., Kilpeläinen, Tuomas O., Loos, R. J. F., Racette, S. B., Sung, Y. J. & Rao, D. C., 2019, In: Human Heredity. 83, 6, p. 315-332Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The antidepressant-like effect of probiotics and their faecal abundance may be modulated by the cohabiting gut microbiota in rats
Abildgaard, A., Kern, T., Pedersen, Oluf Borbye, Hansen, Torben, Wegener, G. & Lund, S., 2019, In: European Neuropsychopharmacology. 29, 1, p. 98-110Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The aromatic amino acid sensor GPR142 controls metabolism through balanced regulation of pancreatic and gut hormones
Rudenko, Olga, Shang, J., Munk, A., Ekberg, J. P., Petersen, N., Engelstoft, M. S., Egerod, Kristoffer Lihme, Hjorth, Siv Annegrethe, Wu, M., Feng, Y., Zhou, Y., Mokrosinski, J., Thams, P., Reimann, F., Gribble, F., Rehfeld, Jens Frederik, Holst, Jens Juul, Treebak, Jonas Thue, Howard, A. D. & Schwartz, Thue W., 2019, In: Molecular Metabolism. 19, p. 49-64 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The brominated flame retardant PBDE 99 promotes adipogenesis via regulating mitotic clonal expansion and PPARγ expression
Wen, Q., Xie, X., Zhao, C., Ren, Q., Zhang, X., Wei, D., Emanuelli, Brice & Du, Y., 2019, In: The Science of the Total Environment. 670, p. 67-77 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The chemistry of the vitamin B3 metabolome
Makarov, M. V., Trammell, Sam & Migaud, M. E., 2019, In: Biochemical Society Transactions. 47, 1, p. 131-147Research output: Contribution to journal › Review › Research › peer-review
- Published
The developing Entorhinal Cortex – a cellular map
Bergmann, T. B., Liu, Y., Lee, J., Pfisterer, U. G., Asenjo Martinez, A., Seemann, Ernst Stefan, Pihl, M., Thomsen, Preben Dybdahl, Hyttel, P., witter, M., Khodosevich, Konstantin, Gorodkin, Jan, Pers, Tune H & Hall, Vanessa Jane, 2019.Research output: Contribution to conference › Conference abstract for conference › Research
- Published
The diurnal variation of bone formation is attenuated in adult patients with type 2 diabetes
Hygum, K., Starup-Linde, J., Harslor, T., Jørgensen, Niklas Rye, Hartmann, Bolette, Holst, Jens Juul & Langdahl, B. L., 2019, In: European Journal of Endocrinology. 181, 3, p. 221-231Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effects of dual GLP-1/GIP receptor agonism on glucagon secretion: a review
Mathiesen, D. S., Bagger, J. I., Bergmann, N. C., Lund, A., Christensen, Mikkel Bring, Vilsbøll, Tina & Knop, Filip Krag, 2019, In: International Journal of Molecular Sciences. 20, 17, 18 p., 4092.Research output: Contribution to journal › Review › Research › peer-review
- Published
The expression of four pyridoxal kinase (PDXK) human variants in Drosophila impacts on genome integrity
Mascolo, E., Barile, A., Mecarelli, L. S., Amoroso, N., Merigliano, C., Massimi, A., Saggio, I., Hansen, Torben, Tramonti, A., Di Salvo, M. L., Barbetti, F., Contestabile, R. & Verni, F., 2019, In: Scientific Reports. 9, 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The incretin system in healthy humans: The role of GIP and GLP-1
Holst, Jens Juul, 2019, In: Metabolism. 96, p. 46-55Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The liver-alpha cell axis and type 2 diabetes
Albrechtsen, Nicolai Jacob Wewer, Pedersen, Jens, Galsgaard, Katrine Douglas, Winther-Sørensen, Marie, Suppli, M. P., Janah, L., Gromada, J., Vilstrup, H., Knop, Filip Krag & Holst, Jens Juul, 2019, In: Endocrine Reviews. 40, 5, p. 1353-1366Research output: Contribution to journal › Review › Research › peer-review
- Published
The microbiome of tunnels in hidradenitis suppurativa patients
Ring, H. C., Sigsgaard, V., Thorsen, Jonathan Jan Ilve, Fuursted, K., Fabricius, S., Saunte, Ditte Marie & Jemec, Gregor, 2019, In: Journal of the European Academy of Dermatology and Venereology : JEADV. 33, 9, p. 1775-1780 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The next decade of metabolism
Backhed, F., Bugianesi, E., Christofk, H., Dikic, I., Gupta, R., Mair, W. B., O'Neill, L. A. J., Ralser, M., Sabatini, D. M. & Tschop, M., 2019, In: Nature Metabolism. 1, p. 2-4Research output: Contribution to journal › Comment/debate › Research
- Published
Time of Exercise Specifies the Impact on Muscle Metabolic Pathways and Systemic Energy Homeostasis
Sato, S., Basse, A. L., Schönke, M., Chen, S., Samad, M., Altıntaş, Ali, Laker, R. C., Kellezi, Emilie Dalbram, Barrès, Romain, Baldi, P., Treebak, Jonas Thue, Zierath, Juleen R & Sassone-Corsi, P., 2019, In: Cell Metabolism. 30, 1, p. 92-110.e4 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tracing the origin of adult intestinal stem cells
Guiu, J., Hannezo, E., Yui, S., Demharter, S., Ulyanchenko, Svetlana, Maimets, Martti, Jørgensen, A., Perlman, S., Lundvall, L., Mamsen, L. S., Larsen, A., Olesen, R. H., Andersen, C. Y., Thuesen, L. L., Hare, Kristine Juul, Pers, Tune H, Khodosevich, Konstantin, Simons, B. D. & Jensen, Kim Bak, 2019, In: Nature. 570, 7759, p. 107-111Research output: Contribution to journal › Letter › Research › peer-review
- Published
Treatment of Active Crohn's Disease With an Ordinary Food-based Diet That Replicates Exclusive Enteral Nutrition
Svolos, V., Hansen, R., Nichols, B., Quince, C., Ijaz, U. Z., Papadopoulou, R. T., Edwards, C. A., Watson, D., Alghamdi, A., Brejnrod, A., Ansalone, C., Duncan, H., Gervais, L., Tayler, R., Salmond, J., Bolognini, D., Klopfleisch, R., Gaya, D. R., Milling, S., Russell, R. K. & 1 others, , 2019, In: Gastroenterology. 156, 5, p. 1354-1367 20 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Trimethylamine-N-Oxide and Renal Complications, Cardiovascular Disease, and Mortality in Individuals with Type 2 Diabetes and Microalbuminuria
Winther, S. A., Øllgaard, J. C., Hansen, T., von Scholten, B. J., Gaede, P., Parving, H., Pedersen, Oluf Borbye & Rossing, Peter, 2019, In: Journal of the American Society of Nephrology. 30, Kidney Week Edition, p. 904 1 p., SA-PO551.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Two-step derivatization for determination of sugar phosphates in plants by combined reversed phase chromatography/tandem mass spectrometry
Rende, U., Niittylae, T. & Moritz, Thomas, 2019, In: Plant Methods. 15, 10 p., 127.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Uncovering the anatomical and molecular landscape of the starting point of Alzheimer’s disease in the brain
Bergmann, T. B., Liu, Y., Lee, J., Pfisterer, U. G., Asenjo Martinez, A., Seemann, Ernst Stefan, Pihl, M., Thomsen, Preben Dybdahl, Hyttel, P., witter, M., Khodosevich, Konstantin, Gorodkin, Jan, Pers, Tune H & Hall, Vanessa Jane, 2019.Research output: Contribution to conference › Conference abstract for conference › Research
- Published
Underpowered or negative? A crucial distinction
Dollerup, O. L., Treebak, Jonas Thue & Jessen, N., 2019, In: Diabetologia. 62, 6, p. 1094-1095 2 p.Research output: Contribution to journal › Comment/debate › Research
- Published
Unge forskere: S-løftebrud er en katastrofe for universiteterne
Aguirre, V., Andersen, C., Andersen, P. R., Bjørk, R., Clemmensen, C., Dalsgaard, P., Danbolt, M., Dimke, H., Engberg-Pedersen, A., Feliu, E., Jauffred, L., Jønsson, K., Kornum, B. R., Kropp, K., Laustsen, A., Levisen, C., Lock, N., Lomborg, S., Møller, N. M., Niss, K. & 5 others, , 2019Research output: Other contribution › Communication
- Published
Utility of Plasma Concentration of Trimethylamine N-Oxide in Predicting Cardiovascular and Renal Complications in Individuals With Type 1 Diabetes
Winther, S. A., Øllgaard, J. C., Tofte, N., Tarnow, L., Wang, Z., Ahluwalia, T. S., Jorsal, A., Theilade, S., Parving, H., Hansen, T. W., Hazen, S. L., Pedersen, Oluf Borbye & Rossing, Peter, 2019, In: Diabetes Care. 42, 8, p. 1512-1520Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Variations in microbiome composition of sewer biofilms due to ferrous and ferric iron dosing
Kiilerich, B., Brejnrod, A. D., Vollertsen, J. & Kiilerich, P., 2019, In: Cogent Environmental Science. 5Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Voluntary wheel running in the late dark phase ameliorates diet-induced obesity in mice without altering insulin action
Kellezi, Emilie Dalbram, Basse, A. L., Zierath, Juleen R & Treebak, Jonas Thue, 2019, In: Journal of Applied Physiology. 126, 4, p. 993-1005 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
WGS-based telomere length analysis in Dutch family trios implicates stronger maternal inheritance and a role for RRM1 gene
Nersisyan, L., Nikoghosyan, M., Francioli, L. C., Menelaou, A., Pulit, S. L., Elbers, C. C., Kloosterman, W. P., van Setten, J., Nijman, I. J., Renkens, I., de Bakker, P. I. W., van Dijk, F., Neerincx, P. B. T., Deelen, P., Kanterakis, A., Dijkstra, M., Byelas, H., van der Velde, K. J., Platteel, M., Swertz, M. A. & 67 others, , 2019, In: Scientific Reports. 9, 9 p., 18758.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Which to choose, an oral or an injectable glucagon-like peptide-1 receptor agonist?
Holst, Jens Juul, 2019, In: The Lancet. 394, 10192, p. 4-6Research output: Contribution to journal › Editorial › Research › peer-review
- Published
Writing from the Gut
Wilkes, J. (ed.), Whiteley, Louise (ed.) & Glerup, C. (ed.), 2019, Medical Museion, University of Copenhagen.Research output: Book/Report › Anthology
- Published
Whole grain-rich diet reduces body weight and systemic low-grade inflammation without inducing major changes of the gut microbiome: a randomised cross-over trial
Roager, H. M., Vogt, J. K., Kristensen, M. B., Hansen, L. B. S., Ibrügger, S., Mærkedahl, R. B., Bahl, M. I., Lind, M. V., Nielsen, R. L., Frøkiær, H., Gøbel, R. J., Landberg, R., Ross, A. B., Brix, S., Holck, J., Meyer, A. S., Sparholt, M. H., Christensen, A. F., Carvalho, V., Hartmann, B. & 18 others, , Jan 2019, In: Gut. 68, 1, p. 83-93 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of liraglutide on body weight and microvascular function in non-diabetic overweight women with coronary microvascular dysfunction
Suhrs, H. E., Raft, K. F., Bové, K., Madsbad, Sten, Holst, Jens Juul, Zander, M. & Prescott, Eva, 2 Jan 2019, In: International Journal of Cardiology. 283, p. 28-34Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of glucagon-like peptide 1 analogs on alcohol intake in alcohol-preferring vervet monkeys
Thomsen, M., Holst, Jens Juul, Molander, A., Linnet, Kristian, Ptito, M. & Fink-Jensen, Anders, Feb 2019, In: Psychopharmacology. 236, 2, p. 603–611Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Chronic high dose P2X7 receptor inhibition exacerbates cancer-induced bone pain
Falk, S., Appel, C. K., Bennedbæk, H. B., Al-Dihaissy, T., Unger, A., Dinkel, K. & Heegaard, Anne-Marie, 15 Feb 2019, In: European Journal of Pharmacology. 845, p. 48-55 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A genome-wide association study of shared risk across psychiatric disorders implicates gene regulation during fetal neurodevelopment
Schork, A. J., Won, H., Appadurai, V., Nudel, R., Gandal, M., Delaneau, O., Revsbech Christiansen, M., Hougaard, D. M., Bækved-Hansen, M., Bybjerg-Grauholm, J., Giørtz Pedersen, M., Agerbo, E., Bøcker Pedersen, C., Neale, B. M., Daly, M. J., Wray, N. R., Nordentoft, M., Mors, O., Børglum, A. D., Bo Mortensen, P. & 4 others, , Mar 2019, In: Nature Neuroscience. 22, 3, p. 353-361Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Microbial fermentation of flaxseed fibers modulates the transcriptome of GPR41-expressing enteroendocrine cells and protects mice against diet-induced obesity
Arora, Tulika, Rudenko, Olga, Egerod, Kristoffer Lihme, Husted, Anna Sofie, Kovatcheva-Datchary, P., Akrami, R., Kristensen, M., Schwartz, Thue W. & Backhed, F., Mar 2019, In: American Journal of Physiology: Endocrinology and Metabolism. 316, 3, p. E453-E463Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of DPP-4-protected GLP-1 (7-36) on coronary microvascular function in obese adults
Nilsson, M., Bové, K. B., Suhrs, E., Hermann, T., Madsbad, Sten, Holst, Jens Juul, Prescott, Eva & Zander, M., Mar 2019, In: IJC Heart and Vasculature. 22, p. 139-144Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids
Bentley, A. R., Sung, Y. J., Brown, M. R., Winkler, T. W., Kraja, A. T., Ntalla, I., Schwander, K., Chasman, D. I., Lim, E., Deng, X., Guo, X., Liu, J., Lu, Y., Cheng, C-Y., Sim, X., Vojinovic, D., Huffman, J. E., Musani, S. K., Li, C., Feitosa, M. F. & 32 others, , Apr 2019, In: Nature Genetics. 51, 4, p. 636-648 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Peptone-mediated glucagon-like peptide-1 secretion depends on intestinal absorption and activation of basolaterally located Calcium-Sensing Receptors
Modvig, Ida Marie, Kuhre, Rune Ehrenreich & Holst, Jens Juul, Apr 2019, In: Physiological Reports. 7, 8, 13 p., e14056.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular dynamics-guided discovery of an ago-allosteric modulator for GPR40/FFAR1
Lückmann, Michael, Trauelsen, Mette, Bentsen, M. A., Nissen, T. A. D., Martins, J., Fallah, Z., Nygaard, M. M., Papaleo, E., Lindorff-Larsen, Kresten, Schwartz, Thue W. & Frimurer, Thomas Michael, 2 Apr 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 14, p. 7123-7128Research output: Contribution to journal › Journal article › Research › peer-review
- Published
FoxK1 and FoxK2 in insulin regulation of cellular and mitochondrial metabolism
Sakaguchi, M., Cai, W., Wang, C., Cederquist, C. T., Damasio, M., Homan, E. P., Batista, T., Ramirez, A. K., Gupta, M. K., Steger, M., Albrechtsen, Nicolai Jacob Wewer, Singh, S. K., Araki, E., Mann, M., Enerbäck, S. & Kahn, C. R., 5 Apr 2019, In: Nature Communications. 10, 1, 17 p., 1582.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differential action of TGR5 agonists on GLP-2 secretion and promotion of intestinal adaptation in a piglet short bowel model
Lin, S., Stoll, B., Robinson, J., Pastor, J. J., Marini, J. C., Ipharraguerre, I. R., Hartmann, Bolette, Holst, Jens Juul, Cruz, S., Lau, P., Olutoye, O., Fang, Z. & Burrin, D. G., May 2019, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 316, 5, p. G641-G652Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Disease Progression and Pharmacological Intervention in a Nutrient-Deficient Rat Model of Nonalcoholic Steatohepatitis
Tolbol, K. S., Stierstorfer, B., Rippmann, J. F., Veidal, S. S., Rigbolt, K. T. G., Schoenberger, T., Gillum, M. P., Hansen, H. H., Vrang, N., Jelsing, J., Feigh, M. & Broermann, A., May 2019, In: Digestive Diseases and Sciences. 64, 5, p. 1238-1256Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide association study identifies 30 loci associated with bipolar disorder
eQTLGen Consortium, E. C., May 2019, In: Nature Genetics. 51, 5, p. 793-803Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dietary Fiber is Essential to Maintain L Cell Secretion and Intestinal Weight
Dal, Jenna Elizabeth Hunt, Hartmann, Bolette, Holst, Jens Juul & Kissow, Hannelouise, 1 May 2019, In: Gastroenterology. 156, 6 (S1), p. S-477Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Gut hormone release after gastric bypass depends on the length of the biliopancreatic limb
Patrício, B. G., Morais, T., Guimarães, M., Veedfald, Simon, Hartmann, Bolette, Hilsted, Linda, Holst, Jens Juul, Nora, M. & Monteiro, M. P., 1 May 2019, In: International Journal of Obesity. 43, 5, p. 1009-1018Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Intestinal Growth in Glucagon Receptor Knockout Mice is Not Associated with the Formation of Aom/DSS-Induced Tumours
Dal, Jenna Elizabeth Hunt, Yassin, M., Olsen, Jørgen, Windeløv, Johanne Agerlin, Galsgaard, Katrine Douglas, Holst, Jens Juul & Kissow, Hannelouise, 1 May 2019, In: Gastroenterology. 156, 6 (S1), 1 p., S-692.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Important Endpoints and Proliferative Markers to Assess Small Intestinal Injury and Adaptation using a Mouse Model of Chemotherapy-Induced Mucositis
Billeschou, Anna, Dal, Jenna Elizabeth Hunt & Kissow, Hannelouise, 12 May 2019, In: Journal of visualized experiments : JoVE. 147, e59236.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bio art and the end of philosophy (Feuerstein & Hegel)
Grünfeld, Martin, 21 May 2019, 1 p.Research output: Other contribution › Net publication - Internet publication › Research › peer-review
- Published
Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls
Broad Genomics Platform, B. G. P., Jun 2019, In: Nature. 570, 7759, p. 71-76 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GIP-induced vasodilation in human adipose tissue involves capillary recruitment
Asmar, M., Asmar, A., Simonsen, L., Dela, Flemming, Holst, Jens Juul & Bulow, J., Jun 2019, In: Endocrine Connections. 8, 6, p. 806-813Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Urinary nucleic acid oxidation product levels show differential associations with pharmacological treatment in patients with type 2 diabetes
Kjaer, L. K., Cejvanovic, V., Henriksen, T., Hansen, Torben, Pedersen, Oluf Borbye, Christensen, C. K., Torp-Pedersen, C., Gerds, Thomas Alexander, Brandslund, I., Mandrup-Poulsen, Thomas & Poulsen, Henrik Enghusen, 3 Jun 2019, In: Free Radical Research. 53, 6, p. 694-703Research output: Contribution to journal › Journal article › Research › peer-review
- Published
DBDS Genomic Cohort, a prospective and comprehensive resource for integrative and temporal analysis of genetic, environmental and lifestyle factors affecting health of blood donors
Hansen, T. F., Banasik, K., Erikstrup, C., Pedersen, O. B., Westergaard, D., Chmura, P. J., Nielsen, K., Thørner, L., Hjalgrim, H., Paarup, H., Larsen, M. A. H., Petersen, M., Jennum, P., Andersen, S., Nyegaard, M., Jemec, G. B. E., Olesen, J., Werge, T., Johansson, P. I., Sørensen, E. & 3 others, , 9 Jun 2019, In: BMJ Open. 9, 6, p. 1-7 7 p., e028401.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of Calcium, Magnesium, and Potassium Concentrations on Ventricular Repolarization in Unselected Individuals
et al., E. A. & Warren, H. R., 25 Jun 2019, In: Journal of the American College of Cardiology. 73, 24, p. 3118-3131Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Extracellular Fluid Volume Expansion Uncovers a Natriuretic Action of GLP-1: A Functional GLP-1–Renal Axis in Man
Asmar, A., Cramon, P. K., Simonsen, L., Asmar, M., Sorensen, Charlotte Mehlin, Madsbad, Sten, Moro, C., Hartmann, Bolette, Jensen, B. L., Holst, Jens Juul & Bülow, J., Jul 2019, In: The Journal of clinical endocrinology and metabolism. 104, 7, p. 2509–2519Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Separate and Combined Effects of GIP and GLP-1 Infusions on Bone Metabolism in Overweight Men without Diabetes
Bergmann, N. C., Lund, A., Gasbjerg, Lærke Smidt, Jørgensen, N. R., Jessen, L., Hartmann, Bolette, Holst, Jens Juul, Christensen, Mikkel Bring, Vilsbøll, Tina & Knop, Filip Krag, Jul 2019, In: The Journal of clinical endocrinology and metabolism. 104, 7, p. 2953–2960Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Augmented GLP-1 Secretion as Seen After Gastric Bypass May Be Obtained by Delaying Carbohydrate Digestion
Martinussen, C., Bojsen-Møller, K. N., Dirksen, C., Svane, M. S., Kristiansen, V. B., Hartmann, Bolette, Holst, Jens Juul & Madsbad, Sten, Aug 2019, In: Journal of Clinical Endocrinology and Metabolism. 104, 8, p. 3233–3244Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Plasma proteome profiling discovers potential biomarkers of non-alcoholic fatty liver disease
Niu, Lili, Gupta, R., Geyer, P. E., Albrechtsen, Nicolai Jacob Wewer, Gluud, Lise Lotte, Santos, A., Doll, S., Holst, Jens Juul, Knop, Filip Krag, Vilsbøll, Tina, Junker, A., Sachs, S., Stemmer, K., Mueller, T. D., Tschoep, M. H., Hofmann, S. M. & Mann, Matthias, Aug 2019, In: Molecular & Cellular Proteomics. 18, 8, p. S71 1 p.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure
Sung, Y. J., de Las Fuentes, L., Winkler, T. W., Chasman, D. I., Bentley, A. R., Kraja, A. T., Ntalla, I., Warren, H. R., Guo, X., Schwander, K., Manning, A. K., Brown, M. R., Aschard, H., Feitosa, M. F., Franceschini, N., Lu, Y., Cheng, C-Y., Sim, X., Vojinovic, D., Marten, J. & 263 others, , 1 Aug 2019, In: Human Molecular Genetics. 28, 15, p. 2615-2633Research output: Contribution to journal › Journal article › Research › peer-review
- Published
“Nutrition or no nutrition?”: Chylothorax or leakage of total parenteral nutrition?
Zasada, I. A., Banner, Jytte & Bugge, A., Sep 2019, In: Forensic Science, Medicine, and Pathology. 15, 3, p. 470–473Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Author Correction: Reproducible, interactive, scalable and extensible microbiome data science using QIIME 2 (Nature Biotechnology, (2019), 37, 8, (852-857), 10.1038/s41587-019-0209-9)
Bolyen, E., Rideout, J. R., Dillon, M. R., Bokulich, N. A., Abnet, C. C., Al-Ghalith, G. A., Alexander, H., Alm, E. J., Arumugam, M., Asnicar, F., Bai, Y., Bisanz, J. E., Bittinger, K., Brejnrod, A., Brislawn, C. J., Brown, C. T., Callahan, B. J., Caraballo-Rodríguez, A. M., Chase, J., Cope, E. K. & 92 others, , 1 Sep 2019, In: Nature Biotechnology. 37, 9, p. 1091 1 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Editorial: Novel biomarkers for type 2 diabetes
Ahluwalia, T. S., Kilpeläinen, Tuomas O., Singh, S. & Rossing, Peter, 1 Sep 2019, In: Frontiers in Endocrinology. 10, p. 1-3 3 p., 649.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
Variants in the fetal genome near pro-inflammatory cytokine genes on 2q13 associate with gestational duration
Liu, X., Helenius, D., Skotte, L., Beaumont, R. N., Wielscher, M., Geller, F., Juodakis, J., Mahajan, A., Bradfield, J. P., Lin, F. T. J., Vogelezang, S., Bustamante, M., Ahluwalia, T. S., Pitkänen, N., Wang, C. A., Bacelis, J., Borges, M. C., Zhang, G., Bedell, B. A., Rossi, R. M. & 54 others, , 2 Sep 2019, In: Nature Communications. 10, 1, 13 p., 3927.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The role of Xist-mediated Polycomb recruitment in the initiation of X-chromosome inactivation
Bousard, A., Raposo, A. C., Żylicz, J. J., Picard, C., Pires, V. B., Qi, Y., Gil, Cláudia, Syx, L., Chang, H. Y., Heard, E. & da Rocha, S. T., 4 Oct 2019, In: EMBO Reports. 20, 10, e48019.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of Nicotinamide Riboside on Endocrine Pancreatic Function and Incretin Hormones in Nondiabetic Men With Obesity
Dollerup, O. L., Trammell, Sam, Hartmann, Bolette, Holst, Jens Juul, Christensen, B., Møller, N., Gillum, M. P., Treebak, Jonas Thue & Jessen, N., 1 Nov 2019, In: The Journal of clinical endocrinology and metabolism. 104, 11, p. 5703-5714 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The developing Entorhinal cortex - a cellular map
Bergmann, T. B., Liu, Y., Lee, J., Pfisterer, U. G., Handfield, L., Asenjo Martinez, A., Seemann, Ernst Stefan, Witter, M., Khodosevich, Konstantin, Gorodkin, Jan, Hemberg, M., Pers, Tune H & Hall, Vanessa Jane, 25 Nov 2019. 1 p.Research output: Contribution to conference › Conference abstract for conference › Communication
- Published
The CODATwins Project: The Current Status and Recent Findings of COllaborative Project of Development of Anthropometrical Measures in Twins
Silventoinen, K., Jelenkovic, A., Yokoyama, Y., Sund, R., Sugawara, M., Tanaka, M., Matsumoto, S., Bogl, L. H., Freitas, D. L., Maia, J. A., Hjelmborg, J. V. B., Aaltonen, S., Piirtola, M., Latvala, A., Calais-Ferreira, L., Oliveira, V. C., Ferreira, P. H., Ji, F., Ning, F., Pang, Z. & 118 others, , Dec 2019, In: Twin Research and Human Genetics. 22, 6, p. 800-808Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Author Correction: Metagenomic analysis of colorectal cancer datasets identifies cross-cohort microbial diagnostic signatures and a link with choline degradation (Nature Medicine, (2019), 25, 4, (667-678), 10.1038/s41591-019-0405-7)
Thomas, A. M., Manghi, P., Asnicar, F., Pasolli, E., Armanini, F., Zolfo, M., Beghini, F., Manara, S., Karcher, N., Pozzi, C., Gandini, S., Serrano, D., Tarallo, S., Francavilla, A., Gallo, G., Trompetto, M., Ferrero, G., Mizutani, S., Shiroma, H., Shiba, S. & 19 others, , 1 Dec 2019, In: Nature Medicine. 25, 12, p. 1948 1 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- 2020
- Published
FUT2–ABO epistasis increases the risk of early childhood asthma and Streptococcus pneumoniae respiratory illnesses
Ahluwalia, T. S., Eliasen, A. U., Sevelsted, A., Pedersen, C-E. T., Stokholm, J., Chawes, B., Bork-Jensen, J., Grarup, N., Pedersen, O., Hansen, T., Linneberg, A., Sharma, A., Weiss, S. T., Evans, M. D., Jackson, D. J., Morin, A., Krogfelt, K. A., Schjørring, S., Mortensen, P. B., Hougaard, D. M. & 13 others, , 2020, In: Nature Communications. 11, 12 p., 6398.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A 2 year physical activity and dietary intervention attenuates the increase in insulin resistance in a general population of children: the PANIC study
Lakka, T. A., Lintu, N., Väistö, J., Viitasalo, A., Sallinen, T., Haapala, E. A., Tompuri, T. T., Soininen, S., Karjalainen, P., Schnurr, T. M., Mikkonen, S., Atalay, M., Kilpeläinen, T. O., Laitinen, T., Laaksonen, D. E., Savonen, K., Brage, S., Schwab, U., Jääskeläinen, J., Lindi, V. & 1 others, , 2020, In: Diabetologia. 63, p. 2270-2281Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Cell-Autonomous Signature of Dysregulated Protein Phosphorylation Underlies Muscle Insulin Resistance in Type 2 Diabetes
Batista, T. M., Jayavelu, A. K., Albrechtsen, Nicolai Jacob Wewer, Iovino, S., Lebastchi, J., Pan, H., Dreyfuss, J. M., Krook, A., Zierath, Juleen R, Mann, Matthias & Kahn, C. R., 2020, In: Cell Metabolism. 32, 5, p. 844-859.e5Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Low Dose of Pasireotide Prevents Hypoglycemia in Roux-en-Y Gastric Bypass-Operated Individuals
Ohrstrom, C. C., Hansen, D. L., Kielgast, U. L., Hartmann, Bolette, Holst, Jens Juul & Worm, Dorte, 2020, In: Obesity Surgery. 30, p. 1605-1610 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Multi-Omics Approach to Liver Diseases: Integration of Single Nuclei Transcriptomics with Proteomics and HiCap Bulk Data in Human Liver
Cavalli, M., Diamanti, K., Pan, G., Spalinskas, R., Kumar, C., Deshmukh, Atul Shahaji, Mann, Matthias, Sahlén, P., Komorowski, J. & Wadelius, C., 2020, In: O M I C S: A Journal of Integrative Biology. 24, 4, 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Potential Role for Endogenous Glucagon in Preventing Post-Bariatric Hypoglycemia
Lobato, C. B., Pereira, S. S., Guimaraes, M., Hartmann, Bolette, Albrechtsen, Nicolai Jacob Wewer, Hilsted, Linda, Holst, Jens Juul, Nora, M. & Monteiro, M. P., 2020, In: Frontiers in Endocrinology. 11, 11 p., 608248.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A community-based transcriptomics classification and nomenclature of neocortical cell types
Yuste, R., Hawrylycz, M., Aalling, N., Aguilar-valles, A., Arendt, D., Arnedillo, R. A., Ascoli, G. A., Bielza, C., Bokharaie, V., Bergmann, T. B., Bystron, I., Capogna, M., Chang, Y., Clemens, A., De Kock, C. P. J., Defelipe, J., Dos Santos, S. E., Dunville, K., Feldmeyer, D., Fiáth, R. & 53 others, , 2020, In: Nature Neuroscience. 23, p. 1456-1468 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A decade of genome discoveries in type 2 diabetes and metabolism
Grarup, N., 2020, University of Copenhagen. 72 p.Research output: Book/Report › Doctoral thesis
- Published
A genome-wide cross-phenotype meta-analysis of the association of blood pressure with migraine
Guo, Y., Rist, P. M., Daghlas, I., Giulianini, F., Gormley, P., Anttila, V., Winsvold, B. S., Palta, P., Esko, T., Pers, T. H., Farh, K. H., Cuenca-Leon, E., Muona, M., Furlotte, N. A., Kurth, T., Ingason, A., McMahon, G., Ligthart, L., Terwindt, G. M., Kallela, M. & 32 others, , 2020, In: Nature Communications. 11, 1, 3368.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A machine learning approach to short-term body weight prediction in a dietary intervention program
Babajide, O., Hissam, T., Anna, P., Anatoliy, G., Astrup, A., Alfredo Martinez, J., Oppert, J. & Sørensen, Thorkild I.A., 2020, Computational Science - ICCS 2020: 20th International Conference, Amsterdam, The Netherlands, June 3-5, 2020. Proceedings, Part IV. Krzhizhanovskaya, V. V., Zavodszky, G., Lees, M. H., Sloot, P. M. A., Dongarra, J. J., Brissos, S. & Teixeira, J. (eds.). Springer, p. 441-455 15 p. (Lecture Notes in Computer Science, Vol. 12140).Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review
- Published
A metabolite roadmap of the wood-forming tissue in Populus tremula
Abreu, I. N., Johansson, A. I., Sokolowska, K., Niittyla, T., Sundberg, B., Hvidsten, T. R., Street, N. R. & Moritz, Thomas, 2020, In: New Phytologist. 228, p. 1559-1572 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
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Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets
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The isoenzyme pattern of LDH does not play a physiological role; except perhaps during fast transitions in energy metabolism
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