Novo Nordisk Foundation Center for Basic Metabolic Research

  1. 2021
  2. Published

    Increased glucagon sensitivity in totally pancreatectomised patients

    Rix, I., Lund, A., Garvey, Lene Heise, Owen, K., Hansen, C., van Hall, Gerrit, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2021, In: Diabetologia. 64, SUPPL 1, p. 118-119 226.

    Research output: Contribution to journalConference abstract in journalResearch

  3. Published

    Instrumental variable analysis using offspring BMI in childhood as an indicator of parental BMI in relation to mortality

    Blond, K., Carslake, D., Gjærde, L. K., Vistisen, D., Sørensen, Thorkild I.A., Smith, G. D. & Baker, J. L., 2021, In: Scientific Reports. 11, 1, 10 p., 22408.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Insulin and 5-aminoimidazole-4-carboxamide ribonucleotide (Aicar) differentially regulate the skeletal muscle cell secretome

    Gonzalez-Franquesa, A., Peijs, Lone, Cervone, D. T., Koçana, C., Zierath, Juleen R & Deshmukh, Atul Shahaji, 2021, In: Proteomes. 9, 3, 16 p., 37.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Insulin resistance genetic risk score and burden of coronary artery disease in patients referred for coronary angiography

    Skals, R., Krogager, M. L., Appel, E. V. R., Schnurr, T. M., Have, C. T., Gislason, Gunnar Hilmar, Poulsen, Henrik Enghusen, Køber, Lars Valeur, Engstrøm, Thomas, Stender, Steen, Hansen, Torben, Grarup, N., Lee, C. J., Andersson, C., Torp-Pedersen, Christian & Weeke, P. E., 2021, In: PLoS ONE. 16, 6, 11 p., 0252855.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Intestinal Adaptation upon Chemotherapy-Induced Intestinal Injury in Mice Depends on GLP-2 Receptor Activation

    Billeschou, Anna, Dal, Jenna Elizabeth Hunt, Ghimire, A., Holst, Jens Juul & Kissow, Hannelouise, 2021, In: Biomedicines. 9, 1, 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Intestinal Growth in Glucagon Receptor Knockout Mice Is Not Associated With the Formation of AOM/DSS-Induced Tumors

    Dal, Jenna Elizabeth Hunt, Yassin, M., Olsen, Jørgen, Hartmann, Bolette, Holst, Jens Juul & Kissow, Hannelouise, 2021, In: Frontiers in Endocrinology. 12, 7 p., 695145.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Investigating GIPR (ant)agonism: A structural analysis of GIP and its receptor

    Smit, F. X., van der Velden, W. J. C., Kizilkaya, Hüsün Sheyma, Nørskov, A., Lückmann, Michael, Hansen, T. N., wbf943, wbf943, Qvotrup, K., Frimurer, Thomas Michael & Rosenkilde, Mette, 2021, In: Structure. 29, 7, p. 679-693.e6 21 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Investigating the causal effect of maternal vitamin B12 and folate levels on offspring birthweight

    Moen, G., Beaumont, R. N., Grarup, N., Sommer, C., Shields, B. M., Lawlor, D. A., Freathy, R. M., Evans, D. M. & Warrington, N. M., 2021, In: International Journal of Epidemiology. 50, 1, p. 179-189 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Investigation of the specificity and mechanism of action of the ULK1/AMPK inhibitor SBI-0206965

    Ahwazi, Danial, Neopane, K., Markby, G. R., Kopietz, F., Ovens, A. J., Dall, M., Hassing, Anna Skab, Gräsle, P., Alshuweishi, Y., Treebak, Jonas Thue, Salt, I. P., Göransson, O., Zeqiraj, E., Scott, J. W. & Sakamoto, Kei, 2021, In: Biochemical Journal. 478, 15, p. 2977-2997 21 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Isolation and characterization of muscle stem cells, fibro-adipogenic progenitors, and macrophages from human skeletal muscle biopsies

    Jensen, J. B., Møller, A. B., Just, J., Mose, M., de Paoli, F. V., Billeskov, T. B., Fred, Rikard Göran, Pers, Tune H, Pedersen, S. B., Petersen, K. K., Bjerre, M., Farup, J. & Jessen, N., 2021, In: American Journal of Physiology - Cell Physiology. 321, 2, p. C257-C268 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published
  13. Published

    Large-scale association analyses identify host factors influencing human gut microbiome composition

    Kurilshikov, A., Medina-Gomez, C., Bacigalupe, R., Radjabzadeh, D., Wang, J., Demirkan, A., Le Roy, C. I., Raygoza Garay, J. A., Finnicum, C. T., Liu, X., Zhernakova, D. V., Bonder, M. J., Hansen, T. H., Frost, F., Rühlemann, M. C., Turpin, W., Moon, J. Y., Kim, H. N., Lüll, K., Barkan, E. & 84 others, Shah, S. A., Fornage, M., Szopinska-Tokov, J., Wallen, Z. D., Borisevich, D., Agreus, L., Andreasson, A., Bang, C., Bedrani, L., Bell, J. T., Bisgaard, H., Boehnke, M., Boomsma, D. I., Burk, R. D., Claringbould, A., Croitoru, K., Davies, G. E., van Duijn, C. M., Duijts, L., Falony, G., Fu, J., van der Graaf, A., Hansen, Torben, Homuth, G., Hughes, D. A., Ijzerman, R. G., Jackson, M. A., Jaddoe, V. W. V., Joossens, M., Jørgensen, T., Keszthelyi, D., Knight, R., Laakso, M., Laudes, M., Launer, L. J., Lieb, W., Lusis, A. J., Masclee, A. A. M., Moll, H. A., Mujagic, Z., Qibin, Q., Rothschild, D., Shin, H., Sørensen, Søren Johannes, Steves, C. J., Thorsen, Jonathan Jan Ilve, Timpson, N. J., Tito, R. Y., Vieira-Silva, S., Völker, U., Völzke, H., Võsa, U., Wade, K. H., Walter, S., Watanabe, K., Weiss, S., Weiss, F. U., Weissbrod, O., Westra, H. J., Willemsen, G., Payami, H., Jonkers, D. M. A. E., Arias Vasquez, A., de Geus, E. J. C., Meyer, K. A., Stokholm, Jakob, Segal, E., Org, E., Wijmenga, C., Kim, H. L., Kaplan, R. C., Spector, T. D., Uitterlinden, A. G., Rivadeneira, F., Franke, A., Lerch, M. M., Franke, L., Sanna, S., D’Amato, M., Pedersen, Oluf Borbye, Paterson, A. D., Kraaij, R., Raes, J. & Zhernakova, A., 2021, In: Nature Genetics. 53, p. 156-165 19 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Leaky Gut as a Potential Culprit for the Paradoxical Dysglycemic Response to Gastric Bypass-Associated Ileal Microbiota

    Hankir, M. K., Seyfried, F., Schellinger, I. N., Schlegel, N. & Arora, Tulika, 2021, In: Metabolites. 11, 3, 10 p., 153.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Lipolysis drives expression of the constitutively active receptor GPR3 to induce adipose thermogenesis

    Sveidahl Johansen, O., Ma, T., Hansen, J. B., Markussen, L. K., Schreiber, R., Reverte-Salisa, L., Dong, H., Christensen, D. P., Sun, W., Gnad, T., Karavaeva, I., Nielsen, T. S., Kooijman, S., Cero, C., Dmytriyeva, O., Shen, Y., Razzoli, M., O'Brien, S. L., Kuipers, E. N., Nielsen, C. H. & 31 others, Orchard, W., Willemsen, N., Jespersen, N. Z., Lundh, M., Sustarsic, E. G., Hallgren, C. M., Frost, M., McGonigle, S., Isidor, Marie Sophie, Broholm, C., Pedersen, Oluf Borbye, Hansen, Jacob B., Grarup, N., Hansen, Torben, Kjær, Andreas, Granneman, J. G., Babu, M. M., Calebiro, D., Nielsen, S., Rydén, M., Soccio, R., Rensen, P. C. N., Treebak, Jonas Thue, Schwartz, Thue W., Emanuelli, Brice, Bartolomucci, A., Pfeifer, A., Zechner, R., Schéele, Camilla Charlotte Nielsen, Mandrup, S. & Gerhart-Hines, Z., 2021, In: Cell. 184, 13, p. 3502-3518 + 50 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Liraglutide decreases postprandial fibroblast growth factor 19 and glucagon-like peptide 2, and increases postprandial cholecystokinin in individuals with obesity

    Bronden, A., Nerild, H. H., Nexoe-Larsen, C. C., Hellmann, P. H., Baekdal, M., Gether, I. M., Gillum, M. P., Hartmann, Bolette, Knudsen, L. B., Jacobsen, L. V., Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina, Sonne, D. P. & Knop, Filip Krag, 2021, In: Diabetologia. 64, SUPPL 1, p. 94-94 177.

    Research output: Contribution to journalConference abstract in journalResearch

  17. Published

    Longitudinal plasma protein profiling of newly diagnosed type 2 diabetes

    Gummesson, A., Björnson, E., Fagerberg, L., Zhong, W., Tebani, A., Edfors, F., Schmidt, C., Lundqvist, A., Adiels, M., Bäckhed, F., Schwenk, J. M., Jansson, P. A., Uhlén, M. & Bergström, G., 2021, In: EBioMedicine. 63, 11 p., 103147.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Loss of Function Glucose-Dependent Insulinotropic Polypeptide Receptor Variants Are Associated With Alterations in BMI, Bone Strength and Cardiovascular Outcomes

    Kizilkaya, Hüsün Sheyma, Sørensen, Kimmie Vestergaard, Kibsgaard, C. J., Gasbjerg, Lærke Smidt, Hauser, Alexander Sebastian, wbf943, wbf943, Grarup, N. & Rosenkilde, Mette, 2021, In: Frontiers in Cell and Developmental Biology. 9, 12 p., 749607.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Lysates of Methylococcus capsulatus Bath induce a lean-like microbiota, intestinal FoxP3+RORγt+IL-17+ Tregs and improve metabolism

    Jensen, B. A. H., Holm, J. B., Larsen, I. S., von Burg, N., Derer, S., Sonne, S. B., Pærregaard, S. I., Damgaard, M. V., Indrelid, S. A., Rivollier, A., Agrinier, A. L., Sulek, K., Arnoldussen, Y. J., Fjære, E., Marette, A., Angell, I. L., Rudi, K., Treebak, J. T., Madsen, L., Åkesson, C. P. & 5 others, Agace, W., Sina, C., Kleiveland, C. R., Kristiansen, Karsten & Lea, T. E., 2021, In: Nature Communications. 12, 19 p., 1093.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Mapping the human genetic architecture of COVID-19

    Niemi, M. E. K., Karjalainen, J., Liao, R. G., Neale, B. M., Daly, M., Ganna, A., Pathak, G. A., Andrews, S. J., Kanai, M., Veerapen, K., Fernandez-Cadenas, I., Schulte, E. C., Striano, P., Marttila, M., Minica, C., Marouli, E., Karim, M. A., Wendt, F. R., Savage, J., Sloofman, L. & 41 others, Butler-Laporte, G., Kim, H., Kanoni, S., Okada, Y., Byun, J., Han, Y., Uddin, M. J., Smith, G. D., Willer, C. J., Buxbaum, J. D., Karjalainen, J., Mehtonen, J., Folkersen, L., Moltke, Ida, Hinney, A., Wang, C., Ellinghaus, D., Brunak, Søren, Castro, P., Guindo Martínez, Marta, Lee, J. Y., Loos, Ruth, Zhao, J. H., Sun, Y. V., Wang, B., Parker, R., Garcia, S. M., Smith, O., Davis, C., COVID-19 Host Genetics Initiative, C. H. G. I., 23andMe COVID-19 Team, 2. C. T., Norwegian SARS-CoV-2 Study Grp, N. S. S. G., Humanitas COVID-19 Task Force, H. C. T. F., Humanitas Gavazzeni COVID-19 Task, H. G. C. T., FHoGID, F., RegCOVID, R., P-PredictUs, P., SeroCOVID, S., CRiPSI, C., Genes & Hlth Res Team, G. &. H. R. T. & UCLA Hlth ATLAS Data Mart Working, U. H. A. D. M. W., 2021, In: Nature. 600, p. 472-477

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Mass-spectrometry-based proteomics reveals mitochondrial supercomplexome plasticity

    Gonzalez-Franquesa, A., Stocks, Ben Nicholas, Chubanava, Sabina, Hattel, H. B., Moreno Justicia, Roger, Peijs, Lone, Treebak, Jonas Thue, Zierath, Juleen R & Deshmukh, Atul Shahaji, 2021, In: Cell Reports. 35, 8, 20 p., 109180.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Maternal anxiety during pregnancy and newborn epigenome-wide DNA methylation

    Sammallahti, S., Cortes Hidalgo, A. P., Tuominen, S., Malmberg, A., Mulder, R. H., Brunst, K. J., Alemany, S., McBride, N. S., Yousefi, P., Heiss, J. A., McRae, N., Page, C. M., Jin, J., Pesce, G., Caramaschi, D., Rifas-Shiman, S. L., Koen, N., Adams, C. D., Magnus, M. C., Baiz, N. & 31 others, Ratanatharathorn, A., Czamara, D., Haberg, S. E., Colicino, E., Baccarelli, A. A., Cardenas, A., DeMeo, D. L., Lawlor, D. A., Relton, C. L., Felix, J. F., van IJzendoorn, M. H., Bakermans-Kranenburg, M. J., Kajantie, E., Raikkonen, K., Sunyer, J., Sharp, G. C., Houtepen, L. C., Nohr, E. A., Sørensen, Thorkild I.A., Tellez-Rojo, M. M., Wright, R. O., Annesi-Maesano, I., Wright, J., Hivert, M., Wright, R. J., Zar, H. J., Stein, D. J., London, S. J., Cecil, C. A. M., Tiemeier, H. & Lahti, J., 2021, In: Molecular Psychiatry. 26, p. 1832–1845 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Maternal cecal microbiota transfer rescues early-life antibiotic-induced enhancement of type 1 diabetes in mice

    Zhang, X. S., Yin, Y. S., Wang, J., Battaglia, T., Krautkramer, K., Li, W. V., Li, J., Brown, M., Zhang, M., Badri, M. H., Armstrong, A. J. S., Strauch, C. M., Wang, Z., Nemet, I., Altomare, N., Devlin, J. C., He, L., Morton, J. T., Chalk, J. A., Needles, K. & 9 others, Liao, V., Mount, J., Li, H., Ruggles, K. V., Bonneau, R. A., Dominguez-Bello, M. G., Bäckhed, F., Hazen, S. L. & Blaser, M. J., 2021, In: Cell Host and Microbe. 29, 8, p. 1249-1265.e9

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Maternal thyroid disease and adiposity in mother and child

    Andersen, S. L., Andersen, S., Liew, Z., Vestergaard, P., Lundbye-Christensen, S., Sørensen, Thorkild I.A. & Olsen, J., 2021, In: Clinical Endocrinology. 94, 3, p. 484-493 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Maximal fat oxidation rate is higher in fit women and unfit women with obesity, compared to normal weight unfit women

    Frandsen, J., Hansen, I. M. D., Wismann, J. F., Olsen, M. H., Brage-Andersen, M. R., Sahl, Ronni Eg, Hansen, M., Ingersen, Arthur, Modvig, J. L., Schmücker, M., brl298, brl298, Dela, Flemming, Larsen, Steen & Helge, Jørn Wulff, 2021, In: Journal of Clinical Endocrinology and Metabolism. 106, 11, p. E4389-E4399 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Mechanism-based inhibitors of SIRT2: structure–activity relationship, X-ray structures, target engagement, regulation of α-tubulin acetylation and inhibition of breast cancer cell migration

    Nielsen, A. L., Rajabi, N., Kudo, N., Jørgensen, Kathrine Lundø, Moreno Yruela, Carlos, Bæk, M., Fontenas, M., Lucidi, A., Madsen, A. S., Yoshida, M. & Olsen, Christian Adam, 2021, In: RSC Chemical Biology. 2, p. 612-626

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Metabolic consequences of obesity and type 2 diabetes: Balancing genes and environment for personalized care

    Pillon, N. J., Loos, R. J. F., Marshall, S. M. & Zierath, Juleen R, 2021, In: Cell. 184, 6, p. 1530-1544 15 p.

    Research output: Contribution to journalReviewResearchpeer-review

  28. Published

    Metformin Lowers Body Weight But Fails to Increase Insulin Sensitivity in Chronic Heart Failure Patients without Diabetes: a Randomized, Double-Blind, Placebo-Controlled Study

    Larsen, A. H., Wiggers, H., Dollerup, O. L., Jespersen, N. R., Hansson, N. H., Frokiaer, J., Brøsen, K., Norrelund, H., Bøtker, H. E., Møller, N. & Jessen, N., 2021, In: Cardiovascular Drugs and Therapy. 35, p. 491-503 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Metformin stimulates intestinal glycolysis and lactate release: A single-dose study of metformin in patients with intrahepatic portosystemic stent

    Rittig, N., Aagaard, N. K., Sundelin, E., Villadsen, G. E., Sandahl, T. D., Holst, Jens Juul, Hartmann, Bolette, Brøsen, K., Grønbaek, H. & Jessen, N., 2021, In: Clinical Pharmacology and Therapeutics. 110, 5, p. 1329-1336

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Microbial regulation of enteroendocrine cells

    Arora, Tulika, Vanslette, A. M., Hjorth, Siv Annegrethe & Backhed, F., 2021, In: Med. 2, 5, p. 553-570 18 p.

    Research output: Contribution to journalReviewResearchpeer-review

  31. Published

    Microbial regulation of hexokinase 2 links mitochondrial metabolism and cell death in colitis

    Hinrichsen, F., Hamm, J., Westermann, M., Schröder, L., Shima, K., Mishra, N., Walker, A., Sommer, N., Klischies, K., Prasse, D., Zimmermann, J., Kaiser, S., Bordoni, D., Fazio, A., Marinos, G., Laue, G., Imm, S., Tremaroli, V., Basic, M., Häsler, R. & 10 others, Schmitz, R. A., Krautwald, S., Wolf, A., Stecher, B., Schmitt-Kopplin, P., Kaleta, C., Rupp, J., Bäckhed, F., Rosenstiel, P. & Sommer, F., 2021, In: Cell Metabolism. 33, 12, p. 2355-2366.e8

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Molecular mechanism of ligand binding pathways and activation of the succinate receptor

    Iliyaz, Aslihan Shenol, Lückmann, Michael, Trauelsen, Mette, Frimurer, Thomas Michael & Schwartz, Thue W., 2021, In: European Biophysics Journal. 50, Suppl. 1, p. 160 1 p., P-234.

    Research output: Contribution to journalConference abstract in journalResearch

  33. Published

    Multi-ancestry genome-wide association study accounting for gene-psychosocial factor interactions identifies novel loci for blood pressure traits

    LifeLines Cohort Study, L. C. S., 2021, In: Human Genetics and Genomics Advances. 2, 1, 12 p., 100013.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Multi-ancestry genome-wide gene-sleep interactions identify novel loci for blood pressure

    Wang, H., Noordam, R., Cade, B. E., Schwander, K., Winkler, T. W., Lee, J., Sung, Y. J., Bentley, A. R., Manning, A. K., Aschard, H., Kilpeläinen, T. O., Ilkov, M., Brown, M. R., Horimoto, A. R., Richard, M., Bartz, T. M., Vojinovic, D., Lim, E., Nierenberg, J. L., Liu, Y. & 105 others, Chitrala, K., Rankinen, T., Musani, S. K., Franceschini, N., Rauramaa, R., Alver, M., Zee, P. C., Harris, S. E., van der Most, P. J., Nolte, I. M., Munroe, P. B., Palmer, N. D., Kühnel, B., Weiss, S., Wen, W., Hall, K. A., Lyytikäinen, L., O'Connell, J., Eiriksdottir, G., Launer, L. J., de Vries, P. S., Arking, D. E., Chen, H., Boerwinkle, E., Krieger, J. E., Schreiner, P. J., Sidney, S., Shikany, J. M., Rice, K., Chen, Y. I., Gharib, S. A., Bis, J. C., Luik, A. I., Ikram, M. A., Uitterlinden, A. G., Amin, N., Xu, H., Levy, D., He, J., Lohman, K. K., Zonderman, A. B., Rice, T. K., Sims, M., Wilson, G., Sofer, T., Rich, S. S., Palmas, W., Yao, J., Guo, X., Rotter, J. I., Biermasz, N. R., Mook-Kanamori, D. O., Martin, L. W., Barac, A., Wallace, R. B., Gottlieb, D. J., Komulainen, P., Heikkinen, S., Mägi, R., Milani, L., Metspalu, A., Starr, J. M., Milaneschi, Y., Waken, R. J., Gao, C., Waldenberger, M., Peters, A., Strauch, K., Meitinger, T., Roenneberg, T., Völker, U., Dörr, M., Shu, X., Mukherjee, S., Hillman, D. R., Kähönen, M., Wagenknecht, L. E., Gieger, C., Grabe, H. J., Zheng, W., Palmer, L. J., Lehtimäki, T., Gudnason, V., Morrison, A. C., Pereira, A. C., Fornage, M., Psaty, B. M., van Duijn, C. M., Liu, C., Kelly, T. N., Evans, M. K., Bouchard, C., Fox, E. R., Kooperberg, C., Zhu, X., Lakka, T. A., Esko, T., North, K. E., Deary, I. J., Snieder, H., Penninx, B. W. J. H., Gauderman, W. J., Rao, D. C., Redline, S. & van Heemst, D., 2021, In: Molecular Psychiatry. 26, p. 6293-6304

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    MultiPep: a hierarchical deep learning approach for multi-label classification of peptide bioactivities

    Grønning, Alexander GB, Kacprowski, T. & Schéele, Camilla Charlotte Nielsen, 2021, In: Biology Methods and Protocols. 6, 1, 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Neprilysin Inhibition Increases Glucagon Levels in Humans and Mice With Potential Effects on Amino Acid Metabolism

    Kjeldsen, Sasha Alexandra Sampson, Hansen, L. H., Esser, N., Mongovin, S., Winther-Sørensen, Marie, Galsgaard, Katrine Douglas, Dal, Jenna Elizabeth Hunt, Kissow, Hannelouise, Ceutz, F. R., Terzic, D., Mark, P. D., Plomgaard, Peter Stendahl, Goetze, Jens P. , Goossens, G. H., Blaak, E. E., Deacon, Carolyn F., Rosenkilde, Mette, Zraika, S., Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2021, In: Endocrine Research. 5, 9, 15 p., bvab084.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    New Insights into Molecular Mechanisms Mediating Adaptation to Exercise: A Review Focusing on Mitochondrial Biogenesis, Mitochondrial Function, Mitophagy and Autophagy

    Roberts, F. L. & Markby, G. R., 2021, In: Cells. 10, 10, 29 p., 2639.

    Research output: Contribution to journalReviewResearchpeer-review

  38. Published

    No effect of dietary fish oil supplementation on the recruitment of brown and brite adipocytes in mice or humans under thermoneutral conditions

    Maurer, S. F., Dieckmann, S., Lund, Jens, Fromme, T., Hess, A. L., Colson, C., Kjølbæk, Louise, Astrup, A., Gillum, M. P., Larsen, L. H., Liebisch, G., Amri, E. & Klingenspor, M., 2021, In: Molecular Nutrition & Food Research. 65, 2, 15 p., 2000681.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    No effects of dapagliflozin, metformin or exercise on plasma glucagon concentrations in individuals with prediabetes: A post hoc analysis from the randomized controlled PRE-D trial

    Clemmensen, K. K. B., Blond, M. B., Amadid, H., Bruhn, L., Vistisen, D., Karstoft, K., Persson, F., Ried-Larsen, M., Holst, Jens Juul, Albrechtsen, Nicolai Jacob Wewer, Torekov, Signe Sørensen, Quist, J. S., Jorgensen, M. E. & Faerch, K., 2021, In: Diabetes, Obesity and Metabolism. 23, 2, p. 530-539

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Non-cell autonomous mechanisms control mitochondrial gene dysregulation in polycystic ovary syndrome

    Moreno-Asso, A., Altıntaş, Ali, McIlvenna, L. C., Patten, R. K., Botella, J., McAinch, A. J., Rodgers, R. J., Barrès, Romain & Stepto, N. K., 2021, In: Journal of Molecular Endocrinology. 68, 1, p. 63-76

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Non-linear interaction between physical activity and polygenic risk score of body mass index in Danish and Russian populations

    Borisevich, D., Schnurr, T. M., pjx571, pjx571, Rakitko, A., Ängquist, Lars, Ilinsky, V., Aadahl, Mette, Grarup, N., Pedersen, Oluf Borbye, Sørensen, Thorkild I.A. & Hansen, Torben, 2021, In: PLoS ONE. 16, 10, 16 p., e0258748.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Nonalcoholic Fatty Liver Disease and Cardiovascular Disease: Overlapping Mechanisms

    Møller, Søren, Kimer, N., Kronborg, T., Grandt, J., Hove, Jens Dahlgaard, Barløse, Mads Christian Johannes & Gluud, Lise Lotte, 2021, In: Seminars in Liver Disease. 41, 03, p. 235-247

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Novel Anti-inflammatory Treatments in Cirrhosis. A Literature-Based Study

    Kronborg, T. M., Lambert, Henriette Ytting, Hobolth, L., Møller, Søren & Kimer, N., 2021, In: Frontiers in Medicine. 8, 718896.

    Research output: Contribution to journalReviewResearchpeer-review

  44. Published

    Obesity treatment effect in Danish children and adolescents carrying Melanocortin-4 Receptor mutations

    Trier, C., Hollensted, M., Schnurr, T. M., Lund, Morten Asp Vonsild, Nielsen, T. R. H., Rui, G., Andersson, E. A., Svendstrup, M., Bille, D. S., Gjesing, A. P., Fonvig, Cilius Esmann, Frithioff-Bojsoe, C., Balslev-Harder, M., Quan, S., Gamborg, Michael Orland, Pedersen, Oluf Borbye, Ängquist, Lars, Holm, Jens-Christian & Hansen, Torben, 2021, In: International Journal of Obesity. 45, p. 66-76 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Ocular Surface Microbiota in Contact Lens Users and Contact-Lens-Associated Bacterial Keratitis

    Andersson, J., Vogt, J. K., Dalgaard, M. D., Pedersen, Oluf Borbye, Holmgaard, Kim & Heegaard, Steffen, 2021, In: Vision (Switzerland). 5, 2, 12 p., 27.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Ocular surface microbiota in patients with aqueous tear-deficient dry eye

    Andersson, J., Vogt, J. K., Dalgaard, M. D., Pedersen, Oluf Borbye, Holmgaard, Kim & Heegaard, Steffen, 2021, In: Ocular Surface. 19, p. 210-217

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Overweight in childhood of exclusively breastfed infants with a high weight at 5 months

    Morgen, C. S., Larsson, M. W., Ängquist, Lars, Sørensen, Thorkild I.A. & Michaelsen, Kim F., 2021, In: Maternal and Child Nutrition. 17, 1, 10 p., e13057.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Paracrine regulation of somatostatin secretion by insulin and glucagon in mouse pancreatic islets

    Svendsen, B. & Holst, Jens Juul, 2021, In: Diabetologia. 64, p. 142–151 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Parenteral nutrition impairs plasma bile acid and gut hormone responses to mixed meal testing in lean healthy men

    Meessen, E. C. E., Bakker, G. J., Nieuwdorp, M., Dallinga-Thie, G. M., Kemper, E. M., Olde Damink, S. W., Romijn, J. A., Hartmann, Bolette, Holst, Jens Juul, Knop, Filip Krag, Groen, A. K., Schaap, F. G. & Soeters, M. R., 2021, In: Clinical Nutrition. 40, 3, p. 1013-1021

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Perinatal exposure to nicotine alters spermatozoal DNA methylation near genes controlling nicotine action

    Altıntaş, Ali, Liu, J., Fabre, O., Chuang, T., Wang, Y., Sakurai, R., Chehabi, G. N., Barrès, Romain & Rehan, V. K., 2021, In: F A S E B Journal. 35, 7, e21702.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Perspectives on the role of brown adipose tissue in human body temperature and metabolism

    Schéele, Camilla Charlotte Nielsen, 2021, In: Cell Reports Medicine. 2, 10, 3 p., 100427.

    Research output: Contribution to journalEditorialResearch

  52. Published

    Pharmacokinetics of exogenous GIP(1-42) in C57Bl/6 mice; Extremely rapid degradation but marked variation between available assays

    Boer, G. A., Hartmann, Bolette & Holst, Jens Juul, 2021, In: Peptides. 136, 7 p., 170457.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Pharmacological but not physiological GDF15 suppresses feeding and the motivation to exercise

    Klein, A. B., Nicolaisen, T. S., Ørtenblad, N., Gejl, K. D., Jensen, R., Fritzen, A. M., Larsen, E. L., Karstoft, K., Poulsen, H. E., Morville, T., Sahl, R. E., Helge, J. W., Lund, J., Falk, S., Lyngbæk, M., Ellingsgaard, H., Pedersen, B. K., Lu, W., Finan, B., Jørgensen, S. B. & 5 others, Seeley, R. J., Kleinert, Maximilian, Kiens, Bente, Richter, Erik A. & Clemmensen, Christoffer, 2021, In: Nature Communications. 12, 9 p., 1041.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Physical activity attenuates postprandial hyperglycaemia in homozygous TBC1D4 loss-of-function mutation carriers

    Schnurr, T. M., Jørsboe, E., Chadt, A., Dahl-Petersen, I. K., Kristensen, Jonas Møller, Wojtaszewski, Jørgen F P, Springer, C., Bjerregaard, P., Brage, S., Pedersen, Oluf Borbye, Moltke, Ida, Grarup, N., Al-Hasani, H., Albrechtsen, Anders, Jørgensen, M. E. & Hansen, Torben, 2021, In: Diabetologia. 64, p. 1795-1804

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    Plasma GDF15 levels are similar between subjects after bariatric surgery and matched controls and are unaffected by meals

    Martinussen, C., Svane, M. S., Bojsen-Møller, K. N., Jensen, Christian Zinck, Kristiansen, V. B., Bookout, A. L., Jorgensen, S. B., Holst, Jens Juul, Albrechtsen, Nicolai Jacob Wewer, Madsbad, Sten & Kuhre, Rune Ehrenreich, 2021, In: American Journal of Physiology: Endocrinology and Metabolism. p. E443-E452 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    Plasma Imidazole Propionate Is Positively Correlated with Blood Pressure in Overweight and Obese Humans

    van Son, J., Serlie, M. J., Stahlman, M., Backhed, F., Nieuwdorp, M. & Aron-Wisnewsky, J., 2021, In: Nutrients. 13, 8, 8 p., 2706.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Plasma levels of glucagon but not GLP-1 are elevated in response to inflammation in humans

    Modrzynska, J., Klein, C. F., Iversen, Kasper, Bundgård, Henning, Hartmann, Bolette, Mose, M., Rittig, N., Møller, N., Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2021, In: Endocrine Connections. 10, 2, p. 205-213 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    Plasma trimethylamine N-oxide and its metabolic precursors and risk of mortality, cardiovascular and renal disease in individuals with type 2-diabetes and albuminuria

    Winther, S. A., Øllgaard, J. C., Hansen, T. W., Von Scholten, B. J., Reinhard, H., Ahluwalia, Tarun Veer Singh, Wang, Z., Gæde, P., Parving, H. H., Hazen, S., Pedersen, Oluf Borbye & Rossing, Peter, 2021, In: PLoS ONE. 16, 3, 14 p., e0244402.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    Population-based pediatric reference values for serum parathyroid hormone, vitamin D, calcium, and phosphate in Danish/North-European white children and adolescents

    Vissing Landgrebe, A., Lund, Morten Asp Vonsild, Lausten-Thomsen, U., Frithioff-Bøjsøe, C., Fonvig, Cilius Esmann, Lind Plesner, J., Aas Holm, L., Jespersen, Thomas, Hansen, Torben & Holm, Jens-Christian, 2021, In: Clinica Chimica Acta. 523, p. 483-490

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    Post-oral fat-induced satiation is mediated by endogenous CCK and GLP-1 in a fat self-administration mouse model

    Vana, V., Lærke, M. K., Kleberg, K., Mroz, P. A., Lindberg, B. L., Ekberg, J. H., Rehfeld, Jens Frederik, Schwartz, Thue W. & Hansen, Harald S., 2021, In: Physiology and Behavior. 234, 12 p., 113315.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published

    Prediabetes Defined by First Measured HbA1c Predicts Higher Cardiovascular Risk Compared With HbA1c in the Diabetes Range: A Cohort Study of Nationwide Registries

    Yahyavi, S. K., Snorgaard, O., Knop, Filip Krag, Schou, Morten, Lee, C., Selmer, C., Gislason, Gunnar Hilmar, Torp-Pedersen, Christian, Blomberg Jensen, M. & Nissen Bonde, A., 2021, In: Diabetes Care. 44, 12, p. 2767-2774 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. Published

    Predictors of Improvement in Quality of Life When Treating Hypothyroidism

    Medici, B. B., Lerche la Cour, J., Knop, Filip Krag, Krakauer, M., Michaelsson, L. F., Faber, Jens, Watt, Torquil & Nygaard, Birte, 2021, In: Journal of Thyroid Research. 2021, 7 p., 5577217.

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    Preserved postprandial suppression of bone turnover markers, despite increased fasting levels, in postmenopausal women

    Abildgaard, J., Ploug, Thorkil, Pedersen, Anette Tønnes, Eiken, P., Pedersen, Bente Klarlund, Holst, Jens Juul, Hartmann, Bolette & Lindegaard, Birgitte, 2021, In: Bone. 143, 8 p., 115612.

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. Published

    Primary prevention of fat and weight gain among obesity susceptible healthy weight preschool children: Main results from the “Healthy Start” randomized controlled intervention

    Olsen, N. J., Ängquist, Lars, Frederiksen, P., Mortensen, Erik Lykke & Lilienthal Heitmann, B., 2021, In: Pediatric Obesity. 16, 4, e12736.

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. Published

    Processes Underlying Glycemic Deterioration in Type 2 Diabetes: An IMI DIRECT Study

    Bizzotto, R., Jennison, C., Jones, A. G., Kurbasic, A., Tura, A., Kennedy, G., Bell, J. D., Thomas, E. L., Frost, G., Eriksen, R., Koivula, R. W., Brage, S., Kaye, J., Hattersley, A. T., Heggie, A., McEvoy, D., 't Hart, L. M., Beulens, J. W., Elders, P., Musholt, P. B. & 28 others, Ridderstrale, M., Hansen, T. H., Allin, K. H., Hansen, Torben, drb459, drb459, Lundgaard, Agnete Troen, Thomsen, Henrik S., De Masi, F., Tsirigos, Konstantinos, Brunak, Søren, Vinuela, A., Mahajan, A., McDonald, T. J., Kokkola, T., Forgie, I. M., Giordano, G. N., Pavo, I., Ruetten, H., Dermitzakis, E., McCarthy, M. I., Pedersen, Oluf Borbye, Schwenk, J. M., Adamski, J., Franks, P. W., Walker, M., Pearson, E. R., Mari, A. & IMI-DIRECT consortium, I. C., 2021, In: Diabetes Care. 44, 2, p. 511-518 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  66. Published

    Profiles of glucose metabolism in different prediabetes phenotypes, classified by fasting glycemia, 2-hour OGTT, glycated hemoglobin, and 1-hour OGTT: An IMI DIRECT study

    Tura, A., Grespan, E., Göbl, C. S., Koivula, R. W., Franks, P. W., Pearson, E. R., Walker, M., Forgie, I. M., Giordano, G. N., Pavo, I., Ruetten, H., Dermitzakis, E. T., McCarthy, M. I., Pedersen, O., Schwenk, J. M., Adamski, J., De Masi, F., Tsirigos, K. D., Brunak, S., Viñuela, A. & 17 others, Mahajan, A., McDonald, T. J., Kokkola, T., Vangipurapu, J., Cederberg, H., Laakso, M., Rutters, F., Elders, P. J. M., Koopman, A. D. M., Beulens, J. W., Ridderstråle, M., Hansen, T. H., Allin, K. H., Hansen, Torben, drb459, drb459, Mari, A. & IMI-DIRECT consortium, I. C., 2021, In: Diabetes. 70, 6, db210227.

    Research output: Contribution to journalJournal articleResearchpeer-review

  67. Published

    Prognostic factors of 90-day mortality in patients hospitalised with covid-19

    Brieghel, C., Ellekvist, P., Lund, M. L., Søborg, C., Walsted, E. S., Thomsen, J. J., Biering-Sørensen, Tor, Mohr, T., Knop, Filip Krag & Ravn, Pernille, 2021, In: Danish Medical Journal. 68, 3, p. 1-9 9 p., A09200705.

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    Prognostic performance of 7 biomarkers compared to liver biopsy in early alcohol-related liver disease

    Rasmussen, D. N., Thiele, M., Johansen, S., Kjærgaard, M., Lindvig, K. P., Israelsen, M., Antonsen, S., Detlefsen, S., Krag, A., Anastasiadou, E., Arumugam, M., Bork, P., Hansen, T., Hartoft, C., Israelsen, H., Karsdal, M., Legido-Quigley, C., Melberg, H. O., Trebicka, J., Mann, M. & 2 others, Matthijnssens, J. & MicrobLiver consortia, M. C., 2021, In: Journal of Hepatology. 75, 5, p. 1017-1025 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. Published

    Protective succinate-SUCNR1 metabolic stress signaling gone bad

    Winther, Sally, Trauelsen, Mette & Schwartz, Thue W., 2021, In: Cell Metabolism. 33, 7, p. 1276-1278 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. Published

    Protein intake, metabolic status and the gut microbiota in different ethnicities: Results from two independent cohorts

    Bel Lassen, P., Attaye, I., Adriouch, S., Nicolaou, M., Aron-Wisnewsky, J., Nielsen, T., Chakaroun, R., Le Chatelier, E., Forslund, S., Belda, E., Bork, P., Bäckhed, F., Stumvoll, M., Pedersen, O., Herrema, H., Groen, A. K., Pinto-Sietsma, S. J., Zwinderman, A. H., Nieuwdorp, M., Clement, K. & 1 others, MetaCardis Consortium, M. C., 2021, In: Nutrients. 13, 9, 3159.

    Research output: Contribution to journalJournal articleResearchpeer-review

  71. Published
  72. Published

    Prototype of an evidence-based tool to aid individualized treatment for type 2 diabetes

    Buse, J. B., Holst, I., Knop, Filip Krag, Kvist, K., Thielke, D. & Pratley, R., 2021, In: Diabetes, Obesity and Metabolism. 23, 7, p. 1666-1671

    Research output: Contribution to journalJournal articleResearchpeer-review

  73. Published

    Quantitative phosphoproteomic analysis of IRS1 in skeletal muscle from men with normal glucose tolerance or type 2 diabetes: A case-control study

    Karlsson, H. K. R., Kasahara, A., Ikeda, M., Chibalin, A. V., Harada, J., Rydén, M., Krook, A., Kato, M., Kubota, K. & Zierath, Juleen R, 2021, In: Metabolism. 118, 7 p., 154726.

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. Published

    Reduced carbohydrate and increased protein and fat during weight loss improve the atherogenic lipid profile in type 2 diabetes

    Thomsen, M. N., Skytte, M. J., Samkani, A., Astrup, A., Frystyk, J., Chabanova, E., Hartmann, Bolette, Holst, Jens Juul, Larsen, T. M., Madsbad, Sten, Magkos, Faidon, Thomsen, Henrik S., Walzem, R. L., Krarup, T. & Haugaard, Steen Bendix, 2021, In: Diabetologia. 64, SUPPL 1, p. 60-60 109.

    Research output: Contribution to journalConference abstract in journalResearch

  75. Published

    Reliability and variation in mitochondrial respiration in human adipose tissue

    Sahl, Ronni Eg, Høy Helms, E. F., Schmücker, Malte, Flensted-Jensen, Mathias, Ingersen, Arthur, Morville, T., Dela, Flemming, Helge, Jørn Wulff & Larsen, S., 2021, In: Adipocytes. 10, 1, p. 605-611 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  76. Published

    Replacing Red Meat with Other Nonmeat Food Sources of Protein is Associated with a Reduced Risk of Type 2 Diabetes in a Danish Cohort of Middle-Aged Adults

    Ibsen, D. B., Jakobsen, M. U., Halkjær, J., Tjønneland, Anne, Kilpeläinen, Tuomas O., Parner, E. T. & Overvad, K., 2021, In: The Journal of Nutrition. 151, 5, p. 1241-1248 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. Published

    Reply to: “Dietary sucrose induces atherosclerotic diseases more than dietary fat in LDLr−/− ApoB100/100 mice: Is it independent of differences in plasma cholesterol levels?”

    Perazza, L. R., Daniel, N., Mitchell, P. L., Jensen, Benjamin Anderschou Holbech & Marette, A., 2021, In: Atherosclerosis. 325, p. 118-120 3 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  78. Published

    Reporting guidelines for human microbiome research: the STORMS checklist

    Mirzayi, C., Renson, A., Furlanello, C., Sansone, S. A., Zohra, F., Elsafoury, S., Geistlinger, L., Kasselman, L. J., Eckenrode, K., van de Wijgert, J., Loughman, A., Marques, F. Z., MacIntyre, D. A., Arumugam, M., Azhar, R., Beghini, F., Bergstrom, K., Bhatt, A., Bisanz, J. E., Braun, J. & 32 others, Bravo, H. C., Buck, G. A., Bushman, F., Casero, D., Clarke, G., Collado, M. C., Cotter, P. D., Cryan, J. F., Demmer, R. T., Devkota, S., Elinav, E., Escobar, J. S., Fettweis, J., Finn, R. D., Fodor, A. A., Forslund, S., Franke, A., Furlanello, C., Gilbert, J., Grice, E., Haibe-Kains, B., Handley, S., Herd, P., Holmes, S., Jacobs, J. P., Karstens, L., Knight, R., Knights, D., Koren, O., Kwon, D. S., Genomic Standards Consortium, G. S. C. & Massive Analysis and Quality Control Society, M. A. A. Q. C. S., 2021, In: Nature Medicine. 27, 11, p. 1885-1892 8 p.

    Research output: Contribution to journalReviewResearchpeer-review

  79. Published

    Revision rates of trapeziometacarpal total joint arthroplasty in relation to occupational hand force requirements

    Kirkeby, L., Frost, Poul, Svendsen, S. W. & Hansen, Torben, 2021, In: Journal of Hand Surgery: European Volume. 46, 9, p. 968-974 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  80. Published

    Risk of Urolithiasis in Patients With Inflammatory Bowel Disease: A Nationwide Danish Cohort Study 1977–2018

    Dimke, H., Winther-Jensen, M., Allin, K. H., Lund, L. & Jess, T., 2021, In: Clinical Gastroenterology and Hepatology. 19, 12, p. 2532-2540.e2

    Research output: Contribution to journalJournal articleResearchpeer-review

  81. Published

    Role of hypothalamic MAPK/ERK signaling and central action of FGF1 in diabetes remission

    Brown, Jenny, Bentsen, M. A., Belmont-Rausch, Dylan Matthew, Phan, B. A., Wieck, D., Wasanwala, H., Matsen, M. E., Acharya, N., Richardson, N. E., Zhao, X., Zhai, P., Secher, A., Morton, G. J., Pers, Tune H, Schwartz, M. W. & Scarlett, J. M., 2021, In: iScience. 24, 9, 19 p., 102944.

    Research output: Contribution to journalJournal articleResearchpeer-review

  82. Published

    Sagittal abdominal diameter and waist circumference appear to be equally good as identifiers of cardiometabolic risk

    Møller, G., Ritz, C., Kjølbæk, Louise, Vuholm, S., Korndal, S. K., Larsen, T. M., Pedersen, Oluf Borbye, Saris, W. H., Astrup, A., Lauritzen, Lotte, Kristensen, M. B. & Lind, M. V., 2021, In: Nutrition, Metabolism & Cardiovascular Diseases. 31, 2, p. 518-527 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  83. Published

    Salivary ghrelin response to drinks varying in protein content and quantity and association with energy intake and appetite.

    Crabtree, D. R., Buosi, W., Fyfe, C. L., Horgan, G. W., Holst, Jens Juul, Johnstone, A. M. & Full4Health-study Group, F. G., 2021, In: Physiology and Behavior. 242, 113622.

    Research output: Contribution to journalJournal articleResearchpeer-review

  84. Published

    Selective release of gastrointestinal hormones induced by an orally active GPR39 agonist

    Grunddal, K. V., Diep, T. A., Petersen, N., Tough, I. R., Skov, Louise Julie, Liu, L., Buijink, J. A., Mende, F., Jin, C., Jepsen, Sara Lind, Sørensen, L. M. E., Achiam, Michael Patrick, Strandby, R. B., Bach, Anders, Hartmann, Bolette, Frimurer, Thomas Michael, Hjorth, Siv Annegrethe, Bouvier, M., Cox, H. & Holst, Birgitte, 2021, In: Molecular Metabolism. 49, 14 p., 101207.

    Research output: Contribution to journalJournal articleResearchpeer-review

  85. Published

    Serum Short-Chain Fatty Acids and Associations With Inflammation in Newly Diagnosed Patients With Multiple Sclerosis and Healthy Controls

    Olsson, A., Gustavsen, S., Nguyen, T. D., Nyman, M., Langkilde, Annika Reynberg, Hansen, T. H., Sellebjerg, Finn Thorup, Oturai, A. B. & Søndergaard, H. B., 2021, In: Frontiers in Immunology. 12, 13 p., 661493.

    Research output: Contribution to journalJournal articleResearchpeer-review

  86. Published

    Short Article Hypothalamic bile acid-TGR5 signaling protects from obesity

    Castellanos-Jankiewicz, A., Guzman-Quevedo, O., Fenelon, V. S., Zizzari, P., Quarta, C., Bellocchio, L., Tailleux, A., Charton, J., Fernandois, D., Henricsson, M., Piveteau, C., Simon, V., Allard, C., Quemener, S., Guinot, V., Hennuyer, N., Perino, A., Duveau, A., Maitre, M., Leste-Lasserre, T. & 13 others, Clark, S., Dupuy, N., Cannich, A., Gonzales, D., Deprez, B., Mithieux, G., Dombrowicz, D., Backhed, F., Prevot, V., Marsicano, G., Staels, B., Schoonjans, K. & Cota, D., 2021, In: Cell Metabolism. 33, 7, p. 1483-1492.e1-e10 21 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  87. Published

    Single-Cell Mapping of GLP-1 and GIP Receptor Expression in the Dorsal Vagal Complex

    Ludwig, M. Q., Todorov, Petar Vladimirov, Egerod, Kristoffer Lihme, Olson, D. P. & Pers, Tune H, 2021, In: Diabetes. 70, 9, p. 1945-1955 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  88. Published

    Sitagliptin, a dipeptidyl peptidase-4 inhibitor, in patients with short bowel syndrome and colon in continuity: an open-label pilot study

    Naimi, R. M., Hvistendahl, M. K., Thomassen, L. M., Johnsen, H., Christiansen, Charlotte Bayer, Holst, Jens Juul, Hartmann, Bolette & Jeppesen, Palle Bekker, 2021, In: BMJ Open Gastroenterology. 8, 1, 10 p., e000604.

    Research output: Contribution to journalJournal articleResearchpeer-review

  89. Published

    Six-day sc GIP infusion increases plasma NEFA without altering the adipose tissue transcriptome, GIPR levels or plasma markers of inflammation in patients with type 1 diabetes

    Heimburger, S. M. N., Hoe, B., Nielsen, C. N., Hartmann, Bolette, Holst, Jens Juul, Dela, Flemming, Overgaard, J., Størling, Joachim, Vilsbøll, Tina, Dejgaard, T. F., Pyke, C., Christensen, M. B. & Knop, Filip Krag, 2021, In: Diabetologia. 64, SUPPL 1, p. 258-258 494.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  90. Published

    Spinal astroglial cannabinoid receptors control pathological tremor

    Carlsen, Eva Maria Meier, Falk, S., Skupio, U., Robin, L., Zottola, A. C. P., Marsicano, G. & Perrier, Jean-Francois Marie, 2021, In: Nature Neuroscience. 24, p. 658–666 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  91. Published

    Structural characterization of the microbial enzyme urocanate reductase mediating imidazole propionate production

    Venskutonytė, R., Koh, A., Stenström, O., Khan, M. T., Lundqvist, A., Akke, M., Bäckhed, F. & Lindkvist-Petersson, K., 2021, In: Nature Communications. 12, 1, 1 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  92. Published

    Structure-Activity Studies of 3,9-Diazaspiro[5.5]undecane-Based ?-Aminobutyric Acid Type A Receptor Antagonists with Immunomodulatory Effect

    Bavo, Francesco, De-Jong, H., Petersen, Jonas Odgaard, Falk-Petersen, C. B., Löffler, R., Sparrow, E., Rostrup, F., Eliasen, Jannik Nicklas, Wilhelmsen, K. S., Barslund, K., Bundgaard, C., Nielsen, Birgitte, Kristiansen, Uffe, Wellendorph, Petrine, Bogdanov, Y. & Frølund, Bente, 2021, In: Journal of Medicinal Chemistry. 64, 24, p. 17795-17812

    Research output: Contribution to journalJournal articleResearchpeer-review

  93. Published

    Subcutaneous GIP and GLP-2 inhibit nightly bone resorption in postmenopausal women: A preliminary study

    Skov-Jeppesen, Kirsa, Veedfald, Simon, Madsbad, Sten, Holst, Jens Juul, Rosenkilde, Mette & Hartmann, Bolette, 2021, In: Bone. 152, 7 p., 116065.

    Research output: Contribution to journalJournal articleResearchpeer-review

  94. Published

    Superficial fungal infections and patients with hidradenitis suppurativa: a study under the Danish Blood Donor Study

    Lindso Andersen, P., Andersen, Rune Kjærsgaard, Jemec, Gregor, Ullum, H., Erikstrup, C., Nielsen, K. R., Bruun, M. T., Hjalgrim, Henrik, Sørensen, E., Burgdorf, K. S., Dinh, K. M., Banasik, Karina, Hansen, T., Saunte, Ditte Marie & Pedersen, Oluf Borbye, 2021, In: Clinical and Experimental Dermatology. 46, 3, p. 571-573 3 p.

    Research output: Contribution to journalLetterResearchpeer-review

  95. Published

    Systematic review and consensus definitions for the Standardized Endpoints in Perioperative Medicine (StEP) initiative: cardiovascular outcomes

    StEP COMPAC Group, S. C. G., 2021, In: British Journal of Anaesthesia. 126, 1, p. 56-66 11 p.

    Research output: Contribution to journalReviewResearchpeer-review

  96. Published

    The Airway Microbiota Modulates Effect of Azithromycin Treatment for Episodes of Recurrent Asthma-like Symptoms in Preschool Children: A Randomized Clinical Trial

    Thorsen, Jonathan Jan Ilve, Stokholm, Jakob, Rasmussen, Morten Arendt, Mortensen, M. S., Brejnrod, A. D., Hjelmsø, M., Shah, S., Chawes, Bo Lund Krogsgaard, Bønnelykke, Klaus, Sørensen, Søren Johannes & Bisgaard, H., 2021, In: American Journal of Respiratory and Critical Care Medicine. 204, 2, p. 149-158

    Research output: Contribution to journalJournal articleResearchpeer-review

  97. Published

    The Biochemical Pathways of Nicotinamide-Derived Pyridones

    Hayat, F., Sonavane, M., Makarov, M. V., Trammell, Sam, McPherson, P., Gassman, N. R. & Migaud, M. E., 2021, In: International Journal of Molecular Sciences. 22, 3, 28 p., 1145.

    Research output: Contribution to journalJournal articleResearchpeer-review

  98. Published

    The C-terminal peptide of CCL21 drastically augments CCL21 activity through the dendritic cell lymph node homing receptor CCR7 by interaction with the receptor N-terminus

    Jørgensen, Astrid Sissel, Brandum, E. P., Mikkelsen, J. M., Orfin, K. A., Boilesen, D. R., Egerod, Kristoffer Lihme, Moussouras, N. A., Vilhardt, Frederik, Kalinski, P., Basse, P., Chen, Yen-Hsi, Yang, Zhang, Dwinell, M. B., Volkman, B. F., Veldkamp, C. T., Holst, Peter Johannes, Lahl, K., Goth, C. K., Rosenkilde, Mette & Hjortø, Gertrud Malene, 2021, In: Cellular and Molecular Life Sciences. 78, p. 6963-6978 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  99. Published

    The Comparative Methylome and Transcriptome After Change of Direction Compared to Straight Line Running Exercise in Human Skeletal Muscle

    Maasar, M. F., Turner, D. C., Gorski, P. P., Seaborne, R. A., Strauss, J. A., Shepherd, S. O., Cocks, M., Pillon, N. J., Zierath, Juleen R, Hulton, A. T., Drust, B. & Sharples, A. P., 2021, In: Frontiers in Physiology. 12, 17 p., 619447.

    Research output: Contribution to journalJournal articleResearchpeer-review

  100. Published

    The Genetic Basis of Hypertriglyceridemia

    Carrasquilla, Germán D., Christiansen, Malene Revsbech & Kilpeläinen, Tuomas O., 2021, In: Current Atherosclerosis Reports. 23, 10 p., 39.

    Research output: Contribution to journalJournal articleResearchpeer-review

  101. Published

    The Glycemic Effect of Liraglutide Evaluated by Continuous Glucose Monitoring in Persons with Type 2 Diabetes Receiving Dialysis

    Bomholt, T., Idorn, T., Knop, Filip Krag, Jørgensen, M. B., Ranjan, A. G., Resuli, M., Hansen, P. M., Borg, Rikke, Persson, F., Feldt-Rasmussen, Bo & Hornum, Mads, 2021, In: Nephron. 145, 1, p. 27-34

    Research output: Contribution to journalJournal articleResearchpeer-review