Novo Nordisk Foundation Center for Basic Metabolic Research

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  1. 2023
  2. Published

    PFAS Exposures and the Human Metabolome: A Systematic Review of Epidemiological Studies

    India-Aldana, S., Yao, M., Midya, V., Colicino, E., Chatzi, L., Chu, J., Gennings, C., Jones, D. P., Loos, Ruth, Setiawan, V. W., Smith, M. R., Walker, R. W., Barupal, D., Walker, D. I. & Valvi, D., 2023, In: Current Pollution Reports. 9, p. 510-568

    Research output: Contribution to journal › Review › Research › peer-review

  3. Published

    PICK1-Deficient Mice Maintain Their Glucose Tolerance During Diet-Induced Obesity

    Backe, M. B., Andersen, Rita Chan, Jensen, M., Jin, C., Hundahl, C., Dmytriyeva, O., Treebak, Jonas Thue, Hansen, J. B., Gerhart-Hines, Zach, Madsen, Kenneth Lindegaard & Holst, Birgitte, 2023, In: Journal of the endocrine society. 7, 6, p. 1-13 bvad057.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Paracrine relationship between incretin hormones and endogenous 5-hydroxytryptamine in the small and large intestine

    Tough, I. R., Lund, M. L., Patel, B. A., Schwartz, Thue W. & Cox, H. M., 2023, In: Neurogastroenterology and Motility. 35, 8, 14 p., e14589.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Physical Activity and Insulin Sensitivity Independently Attenuate the Effect of FTO rs9939609 on Obesity

    Lepola, Mette Andersen, Ängquist, Lars, Bork-Jensen, J., Jonsson, Anna Elisabet, Stinson, Sara, Sandholt, C. H., Thodberg, Malte, Pikkupeura, Laura Maarit, Ongstad, E. L., Grarup, Niels, Astrup, A., Pedersen, Oluf Borbye, Williams, K., Barrès, Romain, Sørensen, Thorkild I.A., Linneberg, Allan René, Grimsby, J., Rhodes, C. J. & Hansen, Torben, 2023, In: Diabetes Care. 46, 5, p. 985–992 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Physiological protection against weight gain: evidence from overfeeding studies and future directions

    Lund, Jens & Clemmensen, Christoffer, 2023, In: Philosophical transactions of the Royal Society of London. Series B, Biological sciences. 378, 1885, 11 p., 2022.0229.

    Research output: Contribution to journal › Review › Research › peer-review

  7. Published

    Plasma metabolite profiles associated with the World Cancer Research Fund/American Institute for Cancer Research lifestyle score and future risk of cardiovascular disease and type 2 diabetes

    Rios, S., García-Gavilán, J. F., Babio, N., Paz-Graniel, I., Ruiz-Canela, M., Liang, L., Clish, C. B., Toledo, E., Corella, D., Estruch, R., Ros, E., Fitó, M., Arós, F., Fiol, M., Guasch-Ferré, M., Santos-Lozano, J. M., Li, J., Razquin, C., Martínez-González, M. Á., Hu, F. B. & 1 others, Salas-Salvadó, J., 2023, In: Cardiovascular Diabetology. 22, 13 p., 252.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Plasma metabolomic profiles associated with mortality and longevity in a prospective analysis of 13,512 individuals

    Wang, F., Tessier, A. J., Liang, L., Wittenbecher, C., Haslam, D. E., Fernández-Duval, G., Heather Eliassen, A., Rexrode, K. M., Tobias, D. K., Li, J., Zeleznik, O., Grodstein, F., Martínez-González, M. A., Salas-Salvadó, J., Clish, C., Lee, K. H., Sun, Q., Stampfer, M. J., Hu, F. B. & Guasch Ferre, Marta, 2023, In: Nature Communications. 14, 1, 11 p., 5744.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Polygenic Scores Help Reduce Racial Disparities in Predictive Accuracy of Automated Type 1 Diabetes Classification Algorithms

    Deutsch, A. J., Stalbow, L., Majarian, T. D., Mercader, J. M., Manning, A. K., Florez, J. C., Loos, Ruth & Udler, M. S., 2023, In: Diabetes Care. 46, 4, p. 794-800 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Portfolio Diet Score and Risk of Cardiovascular Disease: Findings From 3 Prospective Cohort Studies

    Glenn, A. J., Guasch Ferre, Marta, Malik, V. S., Kendall, C. W. C., Manson, J. A. E., Rimm, E. B., Willett, W. C., Sun, Q., Jenkins, D. J. A., Hu, F. B. & Sievenpiper, J. L., 2023, In: Circulation. 148, 22, p. 1750-1763 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Post-prandial secretion of glucagon-like peptide-2 (GLP-2) after carbohydrate-, fat- or protein enriched meals in healthy subjects

    Prahm, A. P., Hvistendahl, M. K., Brandt, Christopher Filtenborg, Blanche, Paul Frédéric, Hartmann, Bolette, Holst, Jens Juul & Jeppesen, Palle Bekker, 2023, In: Peptides. 169, 8 p., 171091.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Postmortem Brains from Subjects with Diabetes Mellitus Display Reduced GLUT4 Expression and Soma Area in Hippocampal Neurons: Potential Involvement of Inflammation

    Yonamine, Caio Yogi, Passarelli, M., Suemoto, C. K., Pasqualucci, C. A., Jacob-Filho, W., Alves, V. A. F., Marie, S. K. N., Correa-Giannella, M. L., Britto, L. R. & Machado, U. F., 2023, In: Cells. 12, 9, 21 p., 1250.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Postprandial secretion of follistatin after gastric bypass surgery and sleeve gastrectomy

    Richter, Michael Martin, Svane, M. S., Kristiansen, V. B., Holst, Jens Juul, Madsbad, Sten & Bojsen-Møller, K. N., 2023, In: Peptides. 163, 8 p., 170978.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Pre-diabetes is associated with attenuation rather than volume of epicardial adipose tissue on computed tomography

    Molnar, D., Björnson, E., Larsson, M., Adiels, M., Gummesson, A., Bäckhed, F., Hjelmgren, O. & Bergström, G., 2023, In: Scientific Reports. 13, 1, 12 p., 1623.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Preanalytical impact on the accuracy of measurements of glucagon, GLP-1 and GIP in clinical trials

    Rasmussen, C., Richter, Michael Martin, Jensen, N. J., Heinz, N., Hartmann, Bolette, Holst, Jens Juul, Kjeldsen, Sasha Alexandra Sampson & Albrechtsen, Nicolai Jacob Wewer, 2023, In: Scandinavian Journal of Clinical and Laboratory Investigation. 83, 8, p. 591-598

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Precision medicine in complex diseases - Molecular subgrouping for improved prediction and treatment stratification

    Johansson, Å., Andreassen, O. A., Brunak, Søren, Franks, P. W., Hedman, H., Loos, Ruth, Meder, B., Melén, E., Wheelock, C. E. & Jacobsson, B., 2023, In: Journal of Internal Medicine. 294, 4, p. 378-396 19 p.

    Research output: Contribution to journal › Review › Research › peer-review

  17. Published

    Precision subclassification of type 2 diabetes: a systematic review

    Misra, S., Wagner, R., Ozkan, B., Schön, M., Sevilla-Gonzalez, M., Prystupa, K., Wang, C. C., Kreienkamp, R. J., Cromer, S. J., Rooney, M. R., Duan, D., Thuesen, A. C. B., Wallace, A. S., Leong, A., Deutsch, A. J., Andersen, M. K., Billings, L. K., Eckel, R. H., Sheu, W. H-H., Hansen, T. & 8 others, Stefan, N., Goodarzi, M. O., Ray, D., Selvin, E., Florez, J. C., Meigs, J. B., Udler, M. S. & ADA/EASD PMDI, A. P., 2023, In: Communications Medicine. 3, 19 p., 138.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Preface: causes of obesity, theories, conjectures and evidence

    Allison, D. B., Sørensen, Thorkild I.A., Hall, K. D. & Speakman, J. R., 2023, In: Philosophical transactions of the Royal Society of London. Series B, Biological sciences. 378, 1885, 2 p., 20220200.

    Research output: Contribution to journal › Editorial › Research

  19. Published

    Pregnancy-Associated Bleeding and Genetics: Five Sequence Variants in the Myometrium and Progesterone Signaling Pathway are associated with postpartum hemorrhage

    Westergaard, D., Steinthorsdottir, V., Stefansdottir, L., Rohde, P. D., Wu, X., Geller, F., Tyrmi, J., Havulinna, A. S., Navais, P. S., Flatley, C., Ostrowski, S. R., Pedersen, O. B., Erikstrup, C., Sørensen, E., Mikkelsen, C., Brun, M. T., Jensen, B. A., Brodersen, T., Ullum, H., Magnus, P. & 8 others, Andreassen, O. A., Njolstad, P. R., Krebs, Lone, Hansen, Thomas Folkmann, Banasik, Karina, Brunak, Søren, Nielsen, Henriette Svarre & FinnGen, F., 2023, medRxiv, 51 p. (medRxiv).

    Research output: Working paper › Preprint › Research

  20. Published

    Primary weight loss failure after Roux-en-Y gastric bypass is characterized by impaired gut-hormone mediated regulation of food intake

    Bojsen-Møller, Kirstine Nyvold, Svane, M. S., Martinussen, C., Dirksen, Carsten Moro, Jørgensen, Nils Bruun, Jensen, Jens-Erik Beck, Jensen, Christian Zinck, Torekov, Signe Sørensen, Kristiansen, V. B., Rehfeld, Jens Frederik, Bork-Jensen, J., Grarup, Niels, Hansen, Torben, Hartmann, Bolette, Holst, Jens Juul & Madsbad, Sten, 2023, In: International Journal of Obesity. 47, 11, p. 1143-1151 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Protocol to assess arteriovenous differences across the liver and hindlimb muscles in mice following treadmill exercise

    Ashcroft, Stephen Paul, Jepsen, Sara Lind, Ehrlich, Amy M, Treebak, Jonas Thue, Holst, Jens Juul & Zierath, Juleen R, 2023, In: STAR Protocols. 4, 1, 11 p., 101985.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Pyruvate dehydrogenase kinase regulates vascular inflammation in atherosclerosis and increases cardiovascular risk

    Forteza, M. J., Berg, M., Edsfeldt, A., Sun, J., Baumgartner, R., Kareinen, I., Casagrande, F. B., Hedin, U., Zhang, S., Vuckovic, I., Dzeja, P. P., Polyzos, K. A., Gisterå, A., Trauelsen, M., Schwartz, T. W., Dib, L., Herrmann, J., Monaco, C., Matic, L., Gonçalves, I. & 1 others, Ketelhuth, D. F. J., 2023, In: Cardiovascular Research. 119, 7, p. 1524-1536 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Quality of life, patient satisfaction, and cardiovascular outcomes of the randomised 2 x 3 factorial Copenhagen insulin and Metformin therapy (CIMT) trial – A detailed statistical analysis plan

    Olsen, M. H., Almdal, Thomas Peter, Madsbad, Sten, Ovesen, C., Gluud, C., Sneppen, S. B., Breum, Leif, Hedetoft, C., Krarup, T., Lundby-Christensen, L., Mathiesen, Elisabeth, Røder, M. E., drb459, drb459, Wiinberg, N. & Jakobsen, J. C., 2023, In: Contemporary Clinical Trials Communications. 33, 101095.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Quantitative differences in synthetic gut microbial inoculums do not affect the final stabilized in vitro community compositions

    Gnanasekaran, Thiyagarajan, Sarathi, Arjun, Fang, Q., Azarm, A., Geraldo, Juliana Assis, Nigro, E. & Arumugam, Mani, 2023, In: mSystems. 8, 4, 16 p., e0124922.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Questioning the fetal microbiome illustrates pitfalls of low-biomass microbial studies

    Kennedy, K. M., de Goffau, M. C., Perez-Muñoz, M. E., Arrieta, M. C., Bäckhed, F., Bork, P., Braun, T., Bushman, F. D., Dore, J., de Vos, W. M., Earl, A. M., Eisen, J. A., Elovitz, M. A., Ganal-Vonarburg, S. C., Gänzle, M. G., Garrett, W. S., Hall, L. J., Hornef, M. W., Huttenhower, C., Konnikova, L. & 26 others, Lebeer, S., Macpherson, A. J., Massey, R. C., McHardy, A. C., Koren, O., Lawley, T. D., Ley, R. E., O’Mahony, L., O’Toole, P. W., Pamer, E. G., Parkhill, J., Raes, J., Rattei, T., Salonen, A., Segal, E., Segata, N., Shanahan, F., Sloboda, D. M., Smith, G. C. S., Sokol, H., Spector, T. D., Surette, M. G., Tannock, G. W., Walker, A. W., Yassour, M. & Walter, J., 2023, In: Nature. 613, 7945, p. 639-649 11 p.

    Research output: Contribution to journal › Review › Research › peer-review

  26. Published

    RNA sequencing unravels novel L cell constituents and mechanisms of GLP-1 secretion in human gastric bypass-operated intestine

    Miskelly, M. G., Lindqvist, A., Piccinin, E., Hamilton, A., Cowan, E., Nergård, B. J., Del Giudice, R., Ngara, M., Cataldo, L. R., Kryvokhyzha, D., Volkov, P., Engelking, L., Artner, I., Lagerstedt, J. O., Eliasson, L., Ahlqvist, E., Moschetta, A., Hedenbro, J. & Wierup, N., 2023, In: Diabetologia. 67, 2, p. 356-370

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    ROS-induced ribosome impairment underlies ZAKα-mediated metabolic decline in obesity and aging

    Snieckute, G., Ryder, L., Vind, A. C., Wu, Z., Arendrup, F. S., Stoneley, M., Chamois, S., Martinez-Val, A., Leleu, M., Dreos, R., Russell, A., Gay, D. M., Genzor, A. V., Choi, B. S-Y., Basse, A. L., Sass, F., Dall, M., Dollet, L. C. M., Blasius, M., Willis, A. E. & 10 others, Lund, Anders H., Treebak, Jonas Thue, Olsen, Jesper Velgaard, Poulsen, Steen Seier, Pownall, M. E., Jensen, Benjamin Anderschou Holbech, Clemmensen, Christoffer, Gerhart-Hines, Zach, Gatfield, D. & Bekker-Jensen, Simon Holst, 2023, In: Science (New York, N.Y.). 382, 6675, 14 p., eadf3208.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Rare Heterozygous Loss-of-Function Variants in the Human GLP-1 Receptor Are Not Associated With Cardiometabolic Phenotypes

    Melchiorsen, Josefine Ulrikke, Sørensen, Kimmie Vestergaard, Bork-Jensen, J., Kizilkaya, Hüsün Sheyma, Gasbjerg, Lærke Smidt, Hauser, Alexander Sebastian, Rungby, Jørgen, Sørensen, H. T., Vaag, Allan, Nielsen, J. S., Pedersen, Oluf Borbye, Linneberg, Allan René, Hartmann, Bolette, Gjesing, A. P., Holst, Jens Juul, Hansen, Torben, Rosenkilde, Mette & Grarup, Niels, 2023, In: Journal of Clinical Endocrinology and Metabolism. 108, 11, p. 2821–2833 38 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Rare variants in long non-coding RNAs are associated with blood lipid levels in the TOPMed whole-genome sequencing study

    Wang, Y., Selvaraj, M. S., Li, X., Li, Z., Holdcraft, J. A., Arnett, D. K., Bis, J. C., Blangero, J., Boerwinkle, E., Bowden, D. W., Cade, B. E., Carlson, J. C., Carson, A. P., Chen, Y. D. I., Curran, J. E., de Vries, P. S., Dutcher, S. K., Ellinor, P. T., Floyd, J. S., Fornage, M. & 31 others, Freedman, B. I., Gabriel, S., Germer, S., Gibbs, R. A., Guo, X., He, J., Heard-Costa, N., Hildalgo, B., Hou, L., Irvin, M. R., Joehanes, R., Kaplan, R. C., Kardia, S. L., Kelly, T. N., Kim, R., Kooperberg, C., Kral, B. G., Levy, D., Li, C., Liu, C., Lloyd-Jone, D., Loos, Ruth, Mahaney, M. C., Martin, L. W., Mathias, R. A., Minster, R. L., Mitchell, B. D., Montasser, M. E., Morrison, A. C., Murabito, J. M. & NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, N. T. F. P. M. (. C., 2023, In: American Journal of Human Genetics. 110, 10, p. 1704-1717 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Rare variants with large effects provide functional insights into the pathology of migraine subtypes, with and without aura

    Bjornsdottir, G., Chalmer, M. A., Stefansdottir, L., Skuladottir, A. T., Einarsson, G., Andresdottir, M., Beyter, D., Ferkingstad, E., Gretarsdottir, S., Halldorsson, B. V., Halldorsson, G. H., Helgadottir, A., Helgason, H., Hjorleifsson Eldjarn, G., Jonasdottir, A., Jonasdottir, A., Jonsdottir, I., Knowlton, K. U., Nadauld, L. D., Lund, S. H. & 30 others, Magnusson, O. T., Melsted, P., Moore, K. H. S., Oddsson, A., Olason, P. I., Sigurdsson, A., Banasik, Karina, Brunak, Søren, Didriksen, Maria, Kogelman, L. J. A., Nielsen, K. R., Sørensen, E., Pedersen, Ole Birger Vesterager, Ullum, H., Bay, J., Burgdorf, Kristoffer Sølvsten, Dowsett, J., Hjalgrim, Henrik, Jacobsen, R. L., Louloudis, Ioannis, Lundgaard, Agnete Troen, Mikkelsen, Christina, Nyegaard, Mette, Henriksen, Alexander Pil, Werge, Thomas, Westergaard, D., Olesen, Jes, Ostrowski, Sisse Rye, Hansen, Thomas Folkmann & DBDS Genetic Consortium, D. G. C., 2023, In: Nature Genetics. 55, 11, p. 1843-1853

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Rationale and design of a prospective, clinical study of kidney biopsies in people with type 2 diabetes and severely increased albuminuria (the PRIMETIME 2 study)

    Møller, M., Borg, Rikke, Bressendorff, I., Fink, L. N., Gravesen, E., Jensen, K. H., Hansen, Torben, Krustrup, D., Persson, F., Rossing, Peter, Sembach, F. E., Thuesen, Anne Cathrine Baun & Hansen, Ditte, 2023, In: BMJ Open. 13, 6, e072216.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Redeeming the Past, Present, and Future

    Arnold, Ken, 2023, In: Centaurus. 65, 2, p. 417-425 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Reduced Expression Level of Protein Phosphatase PPM1E Serves to Maintain Insulin Secretion in Type 2 Diabetes

    Gheibi, S., Cataldo Bascunan, Luis Rodrigo, Hamilton, Alexander, Huang, M., Kalamajski, S., Fex, M. & Mulder, H., 2023, In: Diabetes. 72, 4, p. 455-466 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Regular exercise effectively protects against the aging-associated decline in skeletal muscle NAD content

    Chubanava, Sabina & Treebak, Jonas Thue, 2023, In: Experimental Gerontology. 173, 112109.

    Research output: Contribution to journal › Review › Research › peer-review

  35. Published

    Relationship between lifestyle habits and cardiovascular risk factors in familial hypercholesterolemia

    Dessureault, L., Roy, G., Couture, P., Gangloff, A., Guasch Ferre, Marta, Pérusse, L., Tremblay, A. & Drouin-Chartier, J. P., 2023, In: Nutrition, Metabolism and Cardiovascular Diseases. 33, 10, p. 2044-2052 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Reuniting philosophy and science to advance cancer research

    Pradeu, T., Daignan-Fornier, B., Ewald, A., Germain, P. L., Okasha, S., Plutynski, A., Benzekry, S., Bertolaso, M., Bissell, M., Brown, J. S., Chin-Yee, B., Chin-Yee, I., Clevers, H., Cognet, L., Darrason, M., Farge, E., Feunteun, J., Galon, J., Giroux, E., Green, S. & 18 others, Gross, F., Jaulin, F., Knight, R., Laconi, E., Larmonier, N., Maley, C., Mantovani, A., Moreau, V., Nassoy, P., Rondeau, E., Santamaria, D., Sawai, C. M., Seluanov, A., Sepich-Poore, G. D., Sisirak, V., Solary, E., Yvonnet, Sarah & Laplane, L., 2023, In: Biological Reviews. 98, p. 1668-1686 19 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Rifaximin-α for liver fibrosis in patients with alcohol-related liver disease (GALA-RIF): a randomised, double-blind, placebo-controlled, phase 2 trial

    Israelsen, M., Madsen, B. S., Torp, N., Johansen, S., Hansen, C. D., Detlefsen, S., Andersen, P., Hansen, J. K., Lindvig, K. P., Rasmussen, D. N., Thorhauge, K. H., Kjærgaard, M., Karsdal, M., Hansen, Torben, Arumugam, Mani, Trebicka, J., Thiele, M., Krag, A. & GALAXY, G., 2023, In: The Lancet Gastroenterology and Hepatology. 8, 6, p. 523-532 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Role of sociodemographic, clinical, behavioral, and molecular factors in precision prevention of type 2 diabetes: a systematic review

    Bodhini, D., Morton, R. W., Santhakumar, V., Nakabuye, Mariam, Pomares-Millan, H., Clemmensen, Christoffer, Fitzpatrick, S. L., Guasch Ferre, Marta, Pankow, J. S., Ried-Larsen, M., Franks, P. W., Tobias, D. K., Merino, Jordi, Mohan, V., Loos, Ruth & ADA/EASD Precision Medicine in Diabetes Initiative, A. P. M. I. D. I., 2023, medRxiv.

    Research output: Working paper › Preprint › Research

  39. Published

    Schizophrenia-associated somatic copy-number variants from 12,834 cases reveal recurrent NRXN1 and ABCB11 disruptions

    Maury, E. A., Sherman, M. A., Genovese, G., Gilgenast, T. G., Kamath, T., Burris, S. J., Rajarajan, P., Flaherty, E., Akbarian, S., Chess, A., McCarroll, S. A., Loh, P. R., Phillips-Cremins, J. E., Brennand, K. J., Macosko, E. Z., Walters, J. T. R., O'Donovan, M., Sullivan, P., Werge, T., Pers, T. H. & 2 others, Brain Somatic Mosaicism Network, B. S. M. N. & Psychiatric Genomic Consortium Schizophrenia and CNV workgroup, P. G. C. S. A. C. W., 2023, In: Cell Genomics. 3, 8, 22 p., 100356.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Seasonal light hours modulate peripheral clocks and energy metabolism in mice

    Small, Lewin Barkla, Lundell, L. S., Iversen, Jo Frøkjær, Ehrlich, Amy M, Dall, M., Basse, A. L., Kellezi, Emilie Dalbram, Hansen, Ann Normann, Treebak, Jonas Thue, Barrès, Romain & Zierath, Juleen R, 2023, In: Cell Metabolism. 35, 10, p. 1722-1735.e5 20 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Second international consensus report on gaps and opportunities for the clinical translation of precision diabetes medicine

    Tobias, D. K., Merino, J., Ahmad, A., Aiken, C., Benham, J. L., Bodhini, D., Clark, A. L., Colclough, K., Corcoy, R., Cromer, S. J., Duan, D., Felton, J. L., Francis, E. C., Gillard, P., Gingras, V., Gaillard, R., Haider, E., Hughes, A., Ikle, J. M., Jacobsen, L. M. & 180 others, Kahkoska, A. R., Kettunen, J. L. T., Kreienkamp, R. J., Lim, L. L., Männistö, J. M. E., Massey, R., Mclennan, N. M., Miller, R. G., Morieri, M. L., Most, J., Naylor, R. N., Ozkan, B., Patel, K. A., Pilla, S. J., Prystupa, K., Raghavan, S., Rooney, M. R., Schön, M., Semnani-Azad, Z., Sevilla-Gonzalez, M., Svalastoga, P., Takele, W. W., Tam, C. H. T., Thuesen, Anne Cathrine Baun, Tosur, M., Wallace, A. S., Wang, C. C., Wong, J. J., Yamamoto, J. M., Young, K., Amouyal, C., Lepola, Mette Andersen, Bonham, M. P., Chen, M., Cheng, F., Chikowore, T., Chivers, S. C., Clemmensen, Christoffer, Dabelea, D., Dawed, A. Y., Deutsch, A. J., Dickens, L. T., DiMeglio, L. A., Dudenhöffer-Pfeifer, M., Evans-Molina, C., Fernández-Balsells, M. M., Fitipaldi, H., Fitzpatrick, S. L., Gitelman, S. E., Goodarzi, M. O., Grieger, J. A., Guasch Ferre, Marta, Habibi, N., Hansen, Torben, Huang, C., Harris-Kawano, A., Ismail, H. M., Hoag, B., Johnson, R. K., Jones, A. G., Koivula, R. W., Leong, A., Leung, G. K. W., Libman, I. M., Liu, K., Long, S. A., Lowe, W. L., Morton, R. W., Motala, A. A., Onengut-Gumuscu, S., Pankow, J. S., Pathirana, M., Pazmino, S., Perez, D., Petrie, J. R., Powe, C. E., Quinteros, A., Jain, R., Ray, D., Ried-Larsen, M., Saeed, Z., Santhakumar, V., Kanbour, S., Sarkar, S., Monaco, G. S. F., Scholtens, D. M., Selvin, E., Sheu, W. H. H., Speake, C., Stanislawski, M. A., Steenackers, N., Steck, A. K., Stefan, N., Støy, J., Taylor, R., Tye, S. C., Ukke, G. G., Urazbayeva, M., Van der Schueren, B., Vatier, C., Wentworth, J. M., Hannah, W., White, S. L., Yu, G., Zhang, Y., Zhou, S. J., Beltrand, J., Polak, M., Aukrust, I., de Franco, E., Flanagan, S. E., Maloney, K. A., McGovern, A., Molnes, J., Nakabuye, Mariam, Njølstad, P. R., Pomares-Millan, H., Provenzano, M., Saint-Martin, C., Zhang, C., Zhu, Y., Auh, S., de Souza, R., Fawcett, A. J., Gruber, C., Mekonnen, E. G., Mixter, E., Sherifali, D., Eckel, R. H., Nolan, J. J., Philipson, L. H., Brown, R. J., Billings, L. K., Boyle, K., Costacou, T., Dennis, J. M., Florez, J. C., Gloyn, A. L., Gomez, M. F., Gottlieb, P. A., Greeley, S. A. W., Griffin, K., Hattersley, A. T., Hirsch, I. B., Hivert, M. F., Hood, K. K., Josefson, J. L., Kwak, S. H., Laffel, L. M., Lim, S. S., Loos, Ruth, Ma, R. C. W., Mathieu, C., Mathioudakis, N., Meigs, J. B., Misra, S., Mohan, V., Murphy, R., Oram, R., Owen, K. R., Ozanne, S. E., Pearson, E. R., Perng, W., Pollin, T. I., Pop-Busui, R., Pratley, R. E., Redman, L. M., Redondo, M. J., Reynolds, R. M., Semple, R. K., Sherr, J. L., Sims, E. K., Sweeting, A., Tuomi, T., Udler, M. S., Vesco, K. K., Vilsbøll, Tina, Wagner, R., Rich, S. S. & Franks, P. W., 2023, In: Nature Medicine. 29, 10, p. 2438-2457 20 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Secretion and Impact of Gut Hormones in Obesity and Diabetes

    Holst, Jens Juul, 2023, Encyclopedia of Cell Biology: Systems, Translational and Specialized Cell Aspects of Cell Biology. Bradshaw, R. A., Hart, G. W. & Stahl, P. D. (eds.). 2 ed. Elsevier, Vol. 6. p. 543-550 8 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  43. Published

    Self-organized metabotyping of obese individuals identifies clusters responding differently to bariatric surgery

    Lappa, D., Meijnikman, A. S., Krautkramer, K. A., Olsson, L. M., Aydin, Ö., Van Rijswijk, A. S., Acherman, Y. I. Z., De Brauw, M. L., Tremaroli, V., Olofsson, L. E., Lundqvist, A., Hjorth, Siv Annegrethe, Ji, B., Gerdes, V. E. A., Groen, A. K., Schwartz, Thue W., Nieuwdorp, M., Bäckhed, F. & Nielsen, J., 2023, In: PLoS ONE. 18, 3, 26 p., e0279335.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Serotonin receptor 4 agonism prevents high fat diet induced reduction in GLP-1 in mice

    Vanslette, A. M., Toft, P. B., Lund, M. L., Moritz, Thomas & Arora, Tulika, 2023, In: European Journal of Pharmacology. 960, 176181.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Sex differences in muscle protein expression and DNA methylation in response to exercise training

    Landen, S., Jacques, M., Hiam, D., Alvarez-Romero, J., Schittenhelm, R. B., Shah, A. D., Huang, C., Steele, J. R., Harvey, N. R., Haupt, L. M., Griffiths, L. R., Ashton, K. J., Lamon, S., Voisin, S. & Eynon, N., 2023, In: Biology of Sex Differences. 14, 20 p., 56.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Sleep-Time eating boosts exercise endurance

    Treebak, Jonas Thue, 2023, In: Life Metabolism. 2, 5, 2 p., load029.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Sphingolipids Are Depleted in Alcohol-Related Liver Fibrosis

    Thiele, M., Suvitaival, T., Trošt, K., Kim, M., de Zawadzki, A., Kjaergaard, M., Rasmussen, D. N., Lindvig, K. P., Israelsen, M., Detlefsen, S., Andersen, P., Juel, H. B., Nielsen, T., Georgiou, S., Filippa, V., Kuhn, M., Nishijima, S., Moitinho-Silva, L., Rossing, P., Trebicka, J. & 14 others, Anastasiadou, E., Bork, P., Hansen, T., Legido-Quigley, C., Krag, A., Mann, M., Matthijnssens, J., Arumugam, Mani, Henrar, R., Israelsen, H., Karsdal, M., Melberg, H. O., MicrobLiver Consortium, M. C. & GALAXY Consortium, G. C., 2023, In: Gastroenterology. 164, 7, p. 1248-1260

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Standard procedures for blood withdrawal in conscious male rats induce stress and profoundly affect glucose tolerance and secretion of glucoregulatory hormones

    Pedersen, K., Andersen, H., Fledelius, C., Holst, Jens Juul, Hjuler, S. T. & Kuhre, Rune Ehrenreich, 2023, In: Molecular Metabolism. 69, 101689.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Strong protective effect of the APOL1 p.N264K variant against G2-associated focal segmental glomerulosclerosis and kidney disease

    Gupta, Y., Friedman, D. J., McNulty, M. T., Khan, A., Lane, B., Wang, C., Ke, J., Jin, G., Wooden, B., Knob, A. L., Lim, T. Y., Appel, G. B., Huggins, K., Liu, L., Mitrotti, A., Stangl, M. C., Bomback, A., Westland, R., Bodria, M., Marasa, M. & 60 others, Shang, N., Cohen, D. J., Crew, R. J., Morello, W., Canetta, P., Radhakrishnan, J., Martino, J., Liu, Q., Chung, W. K., Espinoza, A., Luo, Y., Wei, W., Feng, Q., Weng, C., Fang, Y., Kullo, I. J., Naderian, M., Limdi, N., Irvin, M. R., Tiwari, H., Mohan, S., Rao, M., Dube, G. K., Chaudhary, N. S., Gutiérrez, O. M., Judd, S. E., Cushman, M., Lange, L. A., Lange, E. M., Bivona, D. L., Verbitsky, M., Winkler, C. A., Kopp, J. B., Santoriello, D., Batal, I., Pinheiro, S. V. B., Oliveira, E. A., Simoes e Silva, A. C., Pisani, I., Fiaccadori, E., Lin, F., Gesualdo, L., Amoroso, A., Ghiggeri, G. M., D’Agati, V. D., Magistroni, R., Kenny, E. E., Loos, Ruth, Montini, G., Hildebrandt, F., Paul, D. S., Petrovski, S., Goldstein, D. B., Kretzler, M., Gbadegesin, R., Gharavi, A. G., Kiryluk, K., Sampson, M. G., Pollak, M. R. & Sanna-Cherchi, S., 2023, In: Nature Communications. 14, 8 p., 7836.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Structural elucidation of 3-nitrophenylhydrazine derivatives of tricarboxylic acid cycle acids and optimization of their fragmentation to boost sensitivity in liquid chromatography-mass spectrometry

    Hodek, O., Henderson, John David, Argemi Muntadas, Lidia, Khan, Adnan & Moritz, Thomas, 2023, In: Journal of Chromatography - B. 1222, 9 p., 123719.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    Sugar- or artificially-sweetened beverage consumption, physical activity, and risk of cardiovascular disease in US adults

    Pacheco, L. S., Tobias, D. K., Li, Y., Bhupathiraju, S. N., Willett, W. C., Ludwig, D. S., Ebbeling, C. B., Haslam, D. E., Drouin-Chartier, J., Hu, F. B. & Guasch Ferre, Marta, 2023, medRxiv, 29 p.

    Research output: Working paper › Preprint › Research

  52. Published

    Supplementation of cyanidin-3-O-β-glucoside-rich haskap (Lonicera caerulea L.) berry extract attenuates hepatic lipid dysregulation in diet-induced obese mice

    Biswas, Dipsikha, De Silva, A. B. K. H., Mercer, A., Sarkar, S., Kienesberger, P., Langille, M., Rupasinghe, H. P. V. & Pulinilkunnil, T., 2023, In: Journal of Functional Foods. 108, 11 p., 105635.

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    Synergy and oxygen adaptation for development of next-generation probiotics

    Khan, M. T., Dwibedi, C., Sundh, D., Pradhan, M., Kraft, J. D., Caesar, R., Tremaroli, V., Lorentzon, M. & Bäckhed, F., 2023, In: Nature. 620, p. 381-385

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    TBC1D4-S711 controls skeletal muscle insulin sensitization after exercise and contraction

    Kjøbsted, Rasmus, Kristensen, Jonas Møller, Eskesen, N. O., Kido, K., Fjorder, Klara, Damgaard, D. F., Larsen, Jeppe Kjærgaard, Andersen, Nicoline Resen, Birk, Jesper Bratz, Gudiksen, Anders, Treebak, Jonas Thue, Schjerling, Peter, Pilegaard, Henriette & Wojtaszewski, Jørgen F P, 2023, In: Diabetes. 72, 7, p. 857-871 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  55. Published

    TNIK is a conserved regulator of glucose and lipid metabolism in obesity

    Pham, Tang Cam Phung, Dollet, L., Ali, Mona Sadek, Raun, Steffen Henning, Møller, Lisbeth L V, Jafari Kermani, Abbas, Ditzel, N., Andersen, Nicoline Resen, Fritzen, Andreas Mæchel, Gerhart-Hines, Zach, Kiens, Bente, Suomalainen, A., Simpson, S. J., Salling Olsen, M., Kieser, A., Schjerling, Peter, Nieminen, A. I., Richter, Erik A., Havula, E. & Sylow, Lykke, 2023, In: Science Advances. 9, 32, 18 p., eadf7119.

    Research output: Contribution to journal › Journal article › Research › peer-review

  56. Published

    Targeted Analysis of Phosphorylated Metabolites in Biological Samples by HILIC–LC–MS

    Hodek, O., Jiang, W. & Moritz, Thomas, 2023, In: LC-GC North America. 41, 8, p. 354-355 2 p.

    Research output: Contribution to journal › Comment/debate › Research

  57. Published

    Targeted Delivery of Butyrate Improves Glucose Homeostasis, Reduces Hepatic Lipid Accumulation and Inflammation in db/db Mice

    Pedersen, Signe Schultz, Prause, Michala Cecilie Burstein, Sørensen, C., Størling, Joachim, Moritz, Thomas, Mariño, E. & Billestrup, Nils, 2023, In: International Journal of Molecular Sciences. 24, 5, 17 p., 4533.

    Research output: Contribution to journal › Journal article › Research › peer-review

  58. Published

    The GHB analogue HOCPCA improves deficits in cognition and sensorimotor function after MCAO via CaMKIIα

    Griem-Krey, Nane, Klein, A. B., Clausen, B. H., Namini, M. R. J., Nielsen, P. V., Bhuiyan, M., Nagaraja, R. Y., De Silva, T. M., Sobey, C. G., Cheng, H. C., Orset, C., Vivien, D., Lambertsen, K. L., Clarkson, A. N. & Wellendorph, Petrine, 2023, In: Journal of Cerebral Blood Flow and Metabolism. 43, 8, p. 1419-1434

    Research output: Contribution to journal › Journal article › Research › peer-review

  59. Published

    The Prevalence of Polyneuropathy in Type 2 Diabetes Subgroups Based on HOMA2 Indices of β-Cell Function and Insulin Sensitivity

    Kristensen, F. P. B., Christensen, D. H., Callaghan, B. C., Stidsen, J. V., Nielsen, J. S., Højlund, K., Beck-Nielsen, H., Jensen, T. S., Andersen, H., Vestergaard, P., Jessen, N., Olsen, M. H., Hansen, Torben, Brøns, C., Vaag, Allan, Sørensen, H. T. & Thomsen, R. W., 2023, In: Diabetes Care. 46, 8, p. 1546-1555 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  60. Published

    The anorectic and thermogenic effects of pharmacological lactate in male mice are confounded by treatment osmolarity and co-administered counterions

    Lund, J., Breum, A. W., Gil, C., Falk, S., Sass, F., Isidor, M. S., Dmytriyeva, O., Ranea-Robles, P., Mathiesen, C. V., Basse, A. L., Johansen, O. S., Fadahunsi, N., Lund, C., Nicolaisen, T. S., Klein, A. B., Ma, T., Emanuelli, B., Kleinert, M., Sørensen, C. M., Gerhart-Hines, Z. & 1 others, Clemmensen, Christoffer, 2023, In: Nature Metabolism. 5, 4, p. 677-698 22 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  61. Published

    The biochemistry and physiology of long-chain dicarboxylic acid metabolism

    Ranea-Robles, Pablo & Houten, S. M., 2023, In: Biochemical Journal. 480, 9, p. 607-627 21 p.

    Research output: Contribution to journal › Review › Research › peer-review

  62. Published

    The contribution of functional HNF1A variants and polygenic susceptibility to risk of type 2 diabetes in ancestrally diverse populations

    Stalbow, L. A., Preuss, M. H., Smit, Roelof Adriaan Johan, Chami, N., Bjørkhaug, L., Aukrust, I., Gloyn, A. L. & Loos, Ruth, 2023, In: Diabetologia. 66, p. 116-126 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  63. Published

    The dietary regulation of LEAP2 depends on meal composition in mice

    Gradel, Anna Katrina Jógvansdóttir, Holm, Stephanie Kjærulff, Byberg, Sarah, Merkestein, M., Hogendorf, W. F. J., Lund, M. L., Buijink, June D.A., Damgaard, J., Lykkesfeldt, Jens & Holst, Birgitte, 2023, In: FASEB Journal. 37, 6, 21 p., 22923.

    Research output: Contribution to journal › Journal article › Research › peer-review

  64. Published

    The effect of diabetes and the diabetogenic TBC1D4 p.Arg684ter variant on kidney function in Inuit in Greenland

    Overvad, M., Díaz, L. J., Bjerregaard, P., Pedersen, M. L., Larsen, C. V. L., Grarup, Niels, Hansen, Torben, Rossing, Peter & Jørgensen, M. E., 2023, In: International Journal of Circumpolar Health. 82, 8 p., 2191406.

    Research output: Contribution to journal › Journal article › Research › peer-review

  65. Published

    The effect of ferritin-guided iron supplementation among Danish female first-time blood donors

    Drechsler, L. Ø., Boldsen, J. K., Hindhede, L., Aagaard, B., Harritshøj, Lene Holm, Mikkelsen, Christina, Brodersen, T., Brøns, N., Schwinn, M., Hjalgrim, Henrik, Rostgaard, K., Topholm Bruun, M., Ostrowski, Sisse Rye, Pedersen, Ole Birger Vesterager, Mikkelsen, S. & Erikstrup, C., 2023, In: Transfusion. 63, 9, p. 1710-1718 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  66. Published

    The effect of sucrase-isomaltase deficiency on metabolism, food intake and preferences: protocol for a dietary intervention study

    Senftleber, N. K., Pedersen, K. S., Schnoor Jørgensen, C., Pedersen, H., Bjerg Christensen, M. M., Kabel Madsen, E., Andersen, K., Jørsboe, E., Gillum, M. P., Frøst, Michael Bom, Hansen, Torben & Jørgensen, M. E., 2023, In: International Journal of Circumpolar Health. 82, 1, 10 p., 2178067.

    Research output: Contribution to journal › Journal article › Research › peer-review

  67. Published

    The effect of traditional diet on glucose homeostasis in carriers and non-carriers of a common TBC1D4 variant in Greenlandic Inuit: A randomized crossover study

    Lewis, Jack Ivor, Lind, M. V., Møller, G., Hansen, Torben, Pedersen, H., Christensen, M. M. B., Laursen, J. C., Nielsen, S., Ottendahl, C. B., Larsen, C. V. L., Stark, K. D., Bjerregaard, P., Jørgensen, M. E. & Lauritzen, Lotte, 2023, In: British Journal of Nutrition. 130, 11, p. 1871-1884

    Research output: Contribution to journal › Journal article › Research › peer-review

  68. Published

    The expanding incretin universe: from basic biology to clinical translation

    Drucker, D. J. & Holst, Jens Juul, 2023, In: Diabetologia. 66, p. 1765-1779

    Research output: Contribution to journal › Review › Research › peer-review

  69. Published

    The gut microbiota contributes to the pathogenesis of anorexia nervosa in humans and mice

    Fan, Y., Støving, R. K., Berreira Ibraim, S., Hyötyläinen, T., Thirion, F., Arora, T., Lyu, L., Stankevic, E., Hansen, T. H., Déchelotte, P., Sinioja, T., Ragnarsdottir, O., Pons, N., Galleron, N., Quinquis, B., Levenez, F., Roume, H., Falony, G., Vieira-Silva, S., Raes, J. & 6 others, Clausen, L., Telléus, G. K., Bäckhed, F., Oresic, M., Ehrlich, S. D. & Pedersen, Oluf Borbye, 2023, In: Nature Microbiology. 8, p. 787–802

    Research output: Contribution to journal › Journal article › Research › peer-review

  70. Published

    The gut microbiota in multiple sclerosis varies with disease activity

    Thirion, F., Sellebjerg, Finn Thorup, Fan, Yong, Lyu, Liwei, Hansen, T. H., Pons, N., Levenez, F., Quinquis, B., Stankevic, Evelina, Søndergaard, H. B., Dantoft, T. M., Poulsen, C. S., Forslund, S. K., drb459, drb459, Hansen, Torben, Brix, S., Oturai, A., Sørensen, Per Soelberg, Ehrlich, S. D. & Pedersen, Oluf Borbye, 2023, In: Genome Medicine. 15, 17 p., 1.

    Research output: Contribution to journal › Journal article › Research › peer-review

  71. Published

    The importance of endogenously secreted GLP-1 and GIP for postprandial glucose tolerance and β-cell function after Roux-en-Y gastric bypass and sleeve gastrectomy surgery

    Hindsø, M., Hedbäck, N., Svane, M. S., Møller, A., Martinussen, C., Jørgensen, N. B., Dirksen, C., Gasbjerg, Lærke Smidt, Kristiansen, V. B., Hartmann, Bolette, Rosenkilde, Mette, Holst, Jens Juul, Madsbad, Sten & Bojsen-Møller, K. N., 2023, In: Diabetes. 72, 3, p. 336–347

    Research output: Contribution to journal › Journal article › Research › peer-review

  72. Published

    The importance of glucose-dependent insulinotropic polypeptide receptor activation for the effects of tirzepatide

    Gasbjerg, Lærke Smidt, Rosenkilde, Mette, Meier, J. J., Holst, Jens Juul & Knop, Filip Krag, 2023, In: Diabetes, Obesity and Metabolism. 25, 11, p. 3079-3092

    Research output: Contribution to journal › Review › Research › peer-review

  73. Published

    The influence of insulin-related genetic variants on fetal growth, fetal blood flow, and placental weight in a prospective pregnancy cohort

    Reim, Pauline Kromann, pjx571, pjx571, Gybel-Brask, D., Schnurr, T. M., Kelstrup, Louise, Høgdall, Estrid Vilma Solyom & Hansen, Torben, 2023, In: Scientific Reports. 13, 10 p., 19638.

    Research output: Contribution to journal › Journal article › Research › peer-review

  74. Published

    The national child odontology registry (SCOR): a valuable resource for odontological and public health research

    Nygaard, Nikoline, Ängquist, Lars, Midjord-Belstrøm, Daniel, Stankevic, Evelina, Hansen, Torben, Olsen, A., Rosing, Kasper & Markvart, Merete, 2023, In: BMC Oral Health. 23, 13 p., 608.

    Research output: Contribution to journal › Journal article › Research › peer-review

  75. Published

    The naturally occurring GIP(1-30)NH2 is a GIP receptor agonist in humans

    Krogh, L. S. L., Henriksen, K., Stensen, S., Skov-Jeppesen, Kirsa, Bergmann, N. C., Størling, Joachim, Rosenkilde, Mette, Hartmann, Bolette, Holst, Jens Juul, Gasbjerg, Lærke Smidt & Knop, Filip Krag, 2023, In: European Journal of Endocrinology. 188, 1, lvac015.

    Research output: Contribution to journal › Journal article › Research › peer-review

  76. Published

    The potential of tailoring the gut microbiome to prevent and treat cardiometabolic disease

    Chakaroun, R. M., Olsson, L. M. & Bäckhed, F., 2023, In: Nature Reviews Cardiology. 20, p. 217-235

    Research output: Contribution to journal › Review › Research › peer-review

  77. Published

    The power of TOPMed imputation for the discovery of Latino-enriched rare variants associated with type 2 diabetes

    Huerta-Chagoya, A., Schroeder, P., Mandla, R., Deutsch, A. J., Zhu, W., Petty, L., Yi, X., Cole, J. B., Udler, M. S., Dornbos, P., Porneala, B., DiCorpo, D., Liu, C. T., Li, J. H., Szczerbiński, L., Kaur, V., Kim, J., Lu, Y., Martin, A., Eizirik, D. L. & 31 others, Marchetti, P., Marselli, L., Chen, L., Srinivasan, S., Todd, J., Flannick, J., Gubitosi-Klug, R., Levitsky, L., Shah, R., Kelsey, M., Burke, B., Dabelea, D. M., Divers, J., Marcovina, S., Stalbow, L., Loos, Ruth, Darst, B. F., Kooperberg, C., Raffield, L. M., Haiman, C., Sun, Q., McCormick, J. B., Fisher-Hoch, S. P., Ordoñez, M. L., Meigs, J., Baier, L. J., González-Villalpando, C., González-Villalpando, M. E., Orozco, L., García-García, L. & Mexican Biobank, M. B., 2023, In: Diabetologia. 66, p. 1273-1288 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  78. Published

    The social origins of obesity within and across generations

    Hemmingsson, E., Nowicka, P., Ulijaszek, S. & Sørensen, Thorkild I.A., 2023, In: Obesity Reviews. 24, 1, 11 p., e13514.

    Research output: Contribution to journal › Review › Research › peer-review

  79. Published

    Time of day determines postexercise metabolism in mouse adipose tissue

    Pendergrast, L. A., Lundell, L. S., Ehrlich, Amy M, Ashcroft, Stephen Paul, Schönke, M., Basse, A. L., Krook, A., Treebak, Jonas Thue, Dollet, L. & Zierath, Juleen R, 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 8, e2218510120.

    Research output: Contribution to journal › Journal article › Research › peer-review

  80. Published

    Timeless spaces: Field experiments in the physiological study of circadian rhythms, 1938–1963

    Hussey, Kristin D., 2023, In: History and Philosophy of the Life Sciences. 45, 25 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  81. Published

    Tracing the biological roots of obesity resistance in humans

    Lund, Jens, 2023, In: Nature Reviews Endocrinology. 19, p. 500 1 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  82. Published

    Transcriptional and epigenomic profiling identifies YAP signaling as a key regulator of intestinal epithelium maturation

    Pikkupeura, Laura Maarit, Bardini Bressan, Raul, Guiu, J., Chen, Y., Maimets, Martti, Mayer, Daniela, Schweiger, P. J., Hansen, Stine Lind, Maciag, Grzegorz Jerzy, Larsen, Hjalte List, Lõhmussaar, Kadi, Pedersen, M. T., Teves, Joji Marie Yap, Lange, Jette Bornholdt, Benes, V., Sandelin, Albin Gustav & Jensen, Kim Bak, 2023, In: Science Advances. 9, 28, 16 p., eadf9460.

    Research output: Contribution to journal › Journal article › Research › peer-review

  83. Published

    Transient changes to metabolic homeostasis initiate mitochondrial adaptation to endurance exercise

    Dent, J. R., Stocks, Ben Nicholas, Campelj, D. G. & Philp, A., 2023, In: Seminars in Cell and Developmental Biology. 143, p. 3-16

    Research output: Contribution to journal › Review › Research › peer-review

  84. Published

    Type 2 Diabetes risk alleles in Peptidyl-glycine Alpha-amidating Monooxygenase influence GLP-1 levels and response to GLP-1 Receptor Agonists

    Umapathysivam, M. M., Araldi, E., Hastoy, B., Dawed, A. Y., Vatandaslar, H., Sengupta, S., Kaufmann, A., Thomsen, S., Hartmann, B., Jonsson, A. E., Kabakci, H., Thaman, S., Grarup, N., Have, C. T., Færch, K., Gjesing, A. P., Nawaz, S., Cheeseman, J., Neville, M. J., Pedersen, O. & 12 others, Walker, M., Jennison, C., Hattersley, A. T., Hansen, Torben, Karpe, F., Holst, Jens Juul, Jones, A. G., Ristow, M., McCarthy, M. I., Pearson, E. R., Stoffel, M. & Gloyn, A. L., 2023, medRxiv, 35 p.

    Research output: Working paper › Preprint › Research

  85. Published

    Type 2 diabetes candidate genes, including PAX5, cause impaired insulin secretion in human pancreatic islets

    Bacos, K., Perfilyev, A., Karagiannopoulos, A., Cowan, E., Ofori, J. K., Bertonnier-Brouty, L., Rönn, T., Lindqvist, A., Luan, C., Ruhrmann, S., Ngara, M., Nilsson, Å., Gheibi, S., Lyons, C. L., Lagerstedt, J. O., Barghouth, M., Esguerra, J. L. S., Volkov, P., Fex, M., Mulder, H. & 7 others, Wierup, N., Krus, U., Artner, I., Eliasson, L., Prasad, R. B., Cataldo Bascunan, Luis Rodrigo & Ling, C., 2023, In: Journal of Clinical Investigation. 133, 4, 17 p., e163612.

    Research output: Contribution to journal › Journal article › Research › peer-review

  86. Published

    Unanswered questions about the causes of obesity

    Speakman, J. R., Sørensen, Thorkild I.A., Hall, K. D. & Allison, D. B., 2023, In: Science. 381, 6661, p. 944-946 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  87. Published

    Uncovering CNS access of lipidated exendin-4 analogues by quantitative whole-brain 3D light sheet imaging

    Skovbjerg, G., Roostalu, U., Salinas, C. G., Skytte, J. L., Perens, J., Clemmensen, Christoffer, Elster, L., Frich, C. K., Hansen, H. H. & Hecksher-Sørensen, J., 2023, In: Neuropharmacology. 238, 109637.

    Research output: Contribution to journal › Journal article › Research › peer-review

  88. Published

    Unravelling Effects of Rosemary (Rosmarinus officinalis L.) Extract on Hepatic Fat Accumulation and Plasma Lipid Profile in Rats Fed a High-Fat Western-Style Diet

    Madsen, S., Bak, S. Y., Yde, C. C., Jensen, H. M., Knudsen, T. A., Bæch-Laursen, C., Holst, Jens Juul, Laustsen, C. & Hedemann, M. S., 2023, In: Metabolites. 13, 9, 21 p., 974.

    Research output: Contribution to journal › Journal article › Research › peer-review

  89. Published

    Usefulness of Heat Map Explanations for Deep-Learning-Based Electrocardiogram Analysis

    Storås, A. M., Andersen, O. E., Lockhart, S., Thielemann, Roman, Gnesin, Filip Jurijevitj, Thambawita, Vajira Lasantha Bandara, Hicks, S. A., Kanters, Jørgen K., Strümke, I., Halvorsen, P. & Riegler, M. A., 2023, In: Diagnostics. 13, 14, 11 p., 2345.

    Research output: Contribution to journal › Journal article › Research › peer-review

  90. Published

    Variants in EFCAB7 underlie nonsyndromic postaxial polydactyly

    Bilal, M., Khan, H., Khan, M. J., Haack, T. B., Buchert, R., Liaqat, K., Ullah, K., Ahmed, S., Bharadwaj, T., Acharya, A., Peralta, S., Najumuddin, Ali, H., Hasni, M. S., Schrauwen, I., Ullah, A., Ahmad, W. & Leal, S. M., 2023, In: European Journal of Human Genetics. 31, 11, p. 1270-1274

    Research output: Contribution to journal › Journal article › Research › peer-review

  91. Published

    Weight loss by calorie restriction does not alter appetite-regulating gut hormone responses from perfused rat small intestine

    Gerstenberg, M. K., Andersen, Daniel Bjørklund, Torz, L., Castorena, C. M., Bookout, A. L., Hartmann, Bolette, Rehfeld, Jens Frederik, Petersen, N., Holst, Jens Juul & Kuhre, Rune Ehrenreich, 2023, In: Acta Physiologica. 238, 1, 12 p., e13947.

    Research output: Contribution to journal › Journal article › Research › peer-review

  92. Published

    Weight loss maintenance with exercise and liraglutide improves glucose tolerance, glucagon response, and beta cell function

    Jensen, Simon Birk Kjær, Juhl, C. R., Janus, C., Lundgren, J. R., Martinussen, C., Wiingaard, C., Knudsen, C., Frikke-Schmidt, Ruth, Stallknecht, Bente Merete, Holst, Jens Juul, Madsbad, Sten & Torekov, Signe Sørensen, 2023, In: Obesity. 31, 4, p. 977-989 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  93. Published

    What is really known about the effects of nicotinamide riboside supplementation in humans

    Damgaard, Mads Vargas & Treebak, Jonas Thue, 2023, In: Science Advances. 9, 29, 12 p., eadi4862.

    Research output: Contribution to journal › Journal article › Research › peer-review

  94. Published

    Whole exome sequencing identified a novel splice donor site variant in interleukin 2 receptor alpha chain

    Waheed, N., Naseer, M., Haider, N., Suleman, Sufyan & Ullah, A., 2023, In: Immunogenetics. 75, p. 71-79

    Research output: Contribution to journal › Journal article › Research › peer-review

  95. Published

    Biased GLP-2 agonist with strong G protein-coupling but impaired arrestin recruitment and receptor desensitization enhances intestinal growth in mice

    Gabe, M. B. N., Christensen, Liv von Voss, Dal, Jenna Elizabeth Hunt, Gadgaard, S., Gasbjerg, Lærke Smidt, Holst, Jens Juul, Kissow, Hannelouise, Hartmann, Bolette & Rosenkilde, Mette, Jan 2023, In: British Journal of Pharmacology. 180, 13, p. 1674-1689

    Research output: Contribution to journal › Journal article › Research › peer-review

  96. Published

    Genetic architecture of spatial electrical biomarkers for cardiac arrhythmia and relationship with cardiovascular disease

    Young, W. J., Haessler, J., Benjamins, J-W., Repetto, L., Yao, J., Isaacs, A., Harper, A. R., Ramirez, J., Garnier, S., van Duijvenboden, S., Baldassari, A. R., Concas, M. P., Duong, T., Foco, L., Isaksen, J. L., Mei, H., Noordam, R., Nursyifa, C., Richmond, A., Santolalla, M. L. & 74 others, Sitlani, C. M., Soroush, N., Thériault, S., Trompet, S., Aeschbacher, S., Ahmadizar, F., Alonso, A., Brody, J. A., Campbell, A., Correa, A., Darbar, D., De Luca, A., Deleuze, J., Ellervik, Christina, Fuchsberger, C., Goel, A., Grace, C., Guo, X., Hansen, Torben, Heckbert, S. R., Jackson, R. D., Kors, J. A., Lima-Costa, M. F., Linneberg, Allan René, Macfarlane, P. W., Morrison, A. C., Navarro, P., Porteous, D. J., Pramstaller, P. P., Reiner, A. P., Risch, L., Schotten, U., Shen, X., Sinagra, G., Soliman, E. Z., Stoll, M., Tarazona-Santos, E., Tinker, A., Trajanoska, K., Villard, E., Warren, H. R., Whitsel, E. A., Wiggins, K. L., Arking, D. E., Avery, C. L., Conen, D., Girotto, G., Grarup, Niels, Hayward, C., Jukema, J. W., Mook-Kanamori, D. O., Olesen, Morten Steen Salling, Padmanabhan, S., Psaty, B. M., Pattaro, C., Ribeiro, A. L. P., Rotter, J. I., Stricker, B. H., van der Harst, P., van Duijn, C. M., Verweij, N., Wilson, J. G., Orini, M., Charron, P., Watkins, H., Kooperberg, C., Lin, H. J., Wilson, J. F., Kanters, Jørgen K., Sotoodehnia, N., Mifsud, B., Lambiase, P. D., Tereshchenko, L. G. & Munroe, P. B., 14 Mar 2023, In: Nature Communications. 14, 1, 16 p., 1411.

    Research output: Contribution to journal › Journal article › Research › peer-review

  97. 2024
  98. Published

    100 ancient genomes show repeated population turnovers in Neolithic Denmark

    Allentoft, M. E., Sikora, M., Fischer, A., Sjögren, K-G., Ingason, A., Macleod, R., Rosengren, A., Schulz Paulsson, B., Jørkov, M. L. S., Novosolov, M., Stenderup, J., Price, T. D., Mortensen, M. F., Nielsen, A. B., Hede, M. U., Sørensen, L., Nielsen, P. O., Rasmussen, P., Jensen, T. Z. T., Refoyo-Martínez, A. & 48 others, Irving-Pease, Evan, Barrie, William Felix Sinclair, Pearson, A., Sousa da Mota, B., Demeter, Fabrice, Henriksen, Rasmus Henrik Amund, Vimala, Tharsika, McColl, Hugh, Vaughn, A., Vinner, Lasse, Renaud, Gabriel, Stern, A., Johannsen, N. N., Ramsøe, Abigail Daisy, Schork, A. J., Ruter, Anthony Henry, Gotfredsen, Anne Birgitte, Nielsen, B. H., Petersen, Erik Brinch, Kannegaard, E., Hansen, J., Pedersen, K. B., Pedersen, L., Klassen, L., Meldgaard, Morten, Johansen, M., Uldum, O. C., Lotz, P., Lysdahl, P., Bangsgaard, Pernille, Petersen, P. V., Maring, R., Iversen, Rune, Wåhlin, S., Sørensen, S. A., Andersen, S. H., Jørgensen, T., Lynnerup, Niels, Lawson, D. J., Rasmussen, Simon, Korneliussen, Thorfinn Sand, Kjær, Kurt H., Durbin, R., Nielsen, Rasmus, Delaneau, O., Werge, Thomas, Kristiansen, Kristian & Willerslev, Eske, 2024, In: Nature. 625, 7994, p. 329-337 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  99. Published

    Escherichia coli CRISPR arrays from early life fecal samples preferentially target prophages

    Dion, M. B., Shah, S. A., Deng, Ling, Thorsen, Jonathan Jan Ilve, Stokholm, Jakob, Krogfelt, K. A., Schjørring, S., Horvath, P., Allard, A., Nielsen, Dennis Sandris, Petit, M. A. & Moineau, S., 2024, In: The ISME Journal. 18, 1, 9 p., wrae005.

    Research output: Contribution to journal › Journal article › Research › peer-review

  100. Published

    L-valine is a powerful stimulator of GLP-1 secretion in rodents and stimulates secretion through ATP-sensitive potassium channels and voltage-gated calcium channels

    Modvig, Ida Marie, Smits, Mark, Galsgaard, Katrine Douglas, Hjørne, A. P., Drzazga, Anna Katarzyna, Rosenkilde, Mette & Holst, Jens Juul, 2024, In: Nutrition and Diabetes. 14, 11 p., 43.

    Research output: Contribution to journal › Journal article › Research › peer-review

  101. Published

    A genetic association study of circulating coagulation factor VIII and von Willebrand factor levels

    de Vries, P. S., Reventun, P., Brown, M. R., Heath, A. S., Huffman, J. E., Le, N. Q., Bebo, A., Brody, J. A., Temprano-Sagrera, G., Raffield, L. M., Ozel, A. B., Thibord, F., Jain, D., Lewis, J. P., Rodriguez, B. A. T., Pankratz, N., Taylor, K. D., Polasek, O., Chen, M. H., Yanek, L. R. & 32 others, Carrasquilla, Germán D., Marioni, R. E., Kleber, M. E., Trégouët, D. A., Yao, J., Li-Gao, R., Joshi, P. K., Trompet, S., Martinez-Perez, A., Ghanbari, M., Howard, T. E., Reiner, A. P., Arvanitis, M., Ryan, K. A., Bartz, T. M., Rudan, I., Faraday, N., Linneberg, Allan René, Ekunwe, L., Davies, G., Delgado, G. E., Hansen, Torben, Chen, W. M., Jackson, Rebecca, Liu, Y., Loos, Ruth, Rao, Divya, Wang, L., Nielsen, J. B., Kilpeläinen, Tuomas O., Trans-Omics for Precision Medicine (TOPMed) program, T. F. P. M. (. P. & the INVENT consortium, T. I. C., 2024, In: Blood. 143, 18, p. 1845-1855

    Research output: Contribution to journal › Journal article › Research › peer-review

  102. Published

    A genomic mutational constraint map using variation in 76,156 human genomes

    Chen, S., Francioli, L. C., Goodrich, J. K., Collins, R. L., Kanai, M., Wang, Q., Alföldi, J., Watts, N. A., Vittal, C., Gauthier, L. D., Poterba, T., Wilson, M. W., Tarasova, Y., Phu, W., Grant, R., Yohannes, M. T., Koenig, Z., Farjoun, Y., Banks, E., Donnelly, S. & 18 others, Gabriel, S., Gupta, N., Ferriera, S., Tolonen, C., Novod, S., Bergelson, L., Roazen, D., Ruano-Rubio, V., Covarrubias, M., Llanwarne, C., Petrillo, N., Wade, G., Jeandet, T., Munshi, R., Tibbetts, K., Loos, Ruth, Karczewski, K. J. & Genome Aggregation Database Consortium, G. A. D. C., 2024, In: Nature. 625, 7993, p. 92-100 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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