- 2007
- Published
Relationships between the functional PPARalpha Leu162Val polymorphism and obesity, type 2 diabetes, dyslipidaemia, and related quantitative traits in studies of 5799 middle-aged white people
Sparsø, T., Hussain, M. S., Andersen, G., Hainerova, I., Borch-Johnsen, K., Jørgensen, T., Hansen, Torben & Pedersen, Oluf Borbye, 2007, In: Molecular Genetics and Metabolism. 90, 2, p. 205-9 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rosiglitazone monotherapy for type 2 diabetes mellitus-too soon to ADOPT?
Gaede, P. & Pedersen, Oluf Borbye, 2007, In: Nature clinical practice. Endocrinology & metabolism. 3, 6, p. 456-7 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Studies of association of the CASQ1 rs2275703 polymorphism in relation to type 2 diabetes and related quantitative metabolic traits among 7,088 Danish whites
Sparsø, T., Hussain, M. S., Borch-Johnsen, K., Jørgensen, T., Madsbad, Sten, Hansen, Torben, Pedersen, Oluf Borbye & Andersen, G., 2007, In: Molecular Genetics and Metabolism. 92, 3, p. 278-282 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Studies of the common DIO2 Thr92Ala polymorphism and metabolic phenotypes in 7342 Danish white subjects
Grarup, Niels, Lepola, Mette Andersen, Andreasen, C. H., Albrechtsen, Anders, Borch-Johnsen, K., Jørgensen, T., Auwerx, J., Schmitz, O., Hansen, Torben & Pedersen, Oluf Borbye, 2007, In: Journal of Clinical Endocrinology and Metabolism. 92, 1, p. 363-6 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The BIGTT test: a novel test for simultaneous measurement of pancreatic beta-cell function, insulin sensitivity, and glucose tolerance
Hansen, Torben, Drivsholm, Thomas, Urhammer, S. A., Palacios, R. T., Vølund, A., Borch-Johnsen, K. & Pedersen, Oluf Borbye, 2007, In: Diabetes Care. 30, 2, p. 257-262 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The GCKR rs780094 polymorphism is associated with elevated fasting serum triacylglycerol, reduced fasting and OGTT-related insulinaemia, and reduced risk of type 2 diabetes
Sparsø, T., Andersen, G., Nielsen, T., Burgdorf, K. S., Gjesing, A. M. P., Nielsen, A. L., Albrechtsen, Anders, Rasmussen, S. S., Jørgensen, T., Borch-Johnsen, K., Sandbaek, A., Lauritzen, T., Madsbad, Sten, Hansen, Torben & Pedersen, Oluf Borbye, 2007, In: Diabetologia. 51, 1, p. 70-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The functional Pro129Thr variant of the FAAH gene is not associated with various fat accumulation phenotypes in a population-based cohort of 5,801 whites
Jensen, D. P., Lepola, Mette Andersen, Hansen, L., Eiberg, Hans Rudolf Lytchoff, Borch-Johnsen, K., Jørgensen, T., Hansen, Torben, Pedersen, Oluf Borbye & Andreasen, C. H., 2007, In: Journal of Molecular Medicine. 85, 5, p. 445-9 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The “mesh” as evidence – model comparison and alternative interpretations of feedback
Hulme, Oliver James & Whiteley, Louise, 2007, In: Behavioral and Brain Sciences. 30Research output: Contribution to journal › Comment/debate › Communication
- Published
Thiazole- and pyrimidineacetic acid derivatives as CRTH2 receptor ligands, their preparation, pharmaceutical compositions, and use in therapy
Ulven, Trond, Frimurer, Thomas Michael, Rist, Ø., Kostenis, E., Högberg, T., Receveur, J. & Grimstrup, M., 2007, Patent No. WO 2007/062677 A1Research output: Patent
- Published
Two variants on chromosome 17 confer prostate cancer risk, and the one in TCF2 protects against type 2 diabetes
Gudmundsson, J., Sulem, P., Steinthorsdottir, V., Bergthorsson, J. T., Thorleifsson, G., Manolescu, A., Rafnar, T., Gudbjartsson, D., Agnarsson, B. A., Baker, A., Sigurdsson, A., Benediktsdottir, K. R., Jakobsdottir, M., Blondal, T., Stacey, S. N., Helgason, A., Gunnarsdottir, S., Olafsdottir, A., Kristinsson, K. T., Birgisdottir, B. & 55 others, , 2007, In: Nature Genetics. 39, 8, p. 977-983 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Disassociation of bone resorption and formation by GLP-2: a 14-day study in healthy postmenopausal women
Henriksen, D. B., Alexandersen, P., Hartmann, Bolette, Adrian, C. L., Byrjalsen, I., Bone, H. G., Holst, Jens Juul & Christiansen, C., Mar 2007, In: Bone. 40, 3, p. 723-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Studies of the associations between functional beta2-adrenergic receptor variants and obesity, hypertension and type 2 diabetes in 7,808 white subjects
Gjesing, A. P., Andersen, G., Burgdorf, Kristoffer Sølvsten, Borch-Johnsen, K., Jørgensen, T., Hansen, Torben & Pedersen, Oluf Borbye, Mar 2007, In: Diabetologia. 50, 3, p. 563-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Treeterbi and Parallel Treeterbi algorithms: efficient, optimal decoding for ordinary, generalized and pair HMMs.
Keibler, E., Arumugam, Mani & Brent, M. R., Mar 2007, In: Bioinformatics. 23, 5, p. 545-554 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The human PINK1 locus is regulated in vivo by a non-coding natural antisense RNA during modulation of mitochondrial function
Schéele, Camilla Charlotte Nielsen, Petrovic, N., Faghihi, M. A., Lassmann, T., Fredriksson, K., Rooyackers, O., Wahlestedt, C., Good, L. & Timmons, J. A., 15 Mar 2007, In: BMC Genomics. 8, p. 74Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1α
Gerhart-Hines, Zach, Rodgers, J. T., Bare, O., Lerin, C., Kim, S. H., Mostoslavsky, R., Alt, F. W., Wu, Z. & Puigserver, P., 4 Apr 2007, In: EMBO Journal. 26, 7, p. 1913-1923 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bone resorption is decreased postprandially by intestinal factors and glucagon-like peptide-2 is a possible candidate
Holst, Jens Juul, Hartmann, Bolette, Gottschalck, I. B., Jeppesen, Palle Bekker, Miholic, J. & Henriksen, D. B., Jul 2007, In: Scandinavian Journal of Gastroenterology. 42, 7, p. 814-20 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Concentrations of the acute phase reactants high-sensitive C-reactive protein and YKL-40 and of interleukin-6 before and after treatment in patients with acromegaly and growth hormone deficiency
Andreassen, Mikkel, drb459, drb459 & Kristensen, L. Ø., Dec 2007, In: Clinical Endocrinology. 67, 6, p. 909-16 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Discovery and uses of pegvisomant: A growth hormone antagonist
Berryman, D. E., Palmer, A. J., Gosney, E. S., Swaminathan, S., DeSantis, D. & Kopchick, J. J., 1 Dec 2007, In: Endokrynologia Polska. 58, 4, p. 322-329 8 p.Research output: Contribution to journal › Review › Research › peer-review
- 2008
- Published
A Somewhat Subjective Introduction to Gene Mapping through Nonparametric Linkage Analysis
Ängquist, Lars, 2008, Genetic Recombination Research Progress. Schultz, J. H. (ed.). Nova Biomedical Books, 60 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
A Unified Discussion on the Concept of Score Functions Used in the Context of Nonparametric Linkage Analysis
Ängquist, Lars, 2008, In: Bioinformatics and Biology Insights. 2, p. 119-132 PMID:19812770.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A candidate type 2 diabetes polymorphism near the HHEX locus affects acute glucose-stimulated insulin release in European populations: results from the EUGENE2 study
Staiger, H., Stancáková, A., Zilinskaite, J., Vänttinen, M., Hansen, T., Marini, M. A., Hammarstedt, A., Jansson, P., Sesti, G., Smith, U., Pedersen, Oluf Borbye, Laakso, M., Stefan, N., Fritsche, A. & Häring, H., 2008, In: Diabetes. 57, 2, p. 514-7 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
AHSG tag single nucleotide polymorphisms associate with type 2 diabetes and dyslipidemia: studies of metabolic traits in 7,683 white Danish subjects
Andersen, G., Burgdorf, K. S., Sparsø, T., Borch-Johnsen, K., Jørgensen, T., Hansen, T. & Pedersen, Oluf Borbye, 2008, In: Diabetes. 57, 5, p. 1427-32 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association of the beta3-adrenergic receptor Trp64Arg polymorphism with common metabolic traits: studies of 7605 middle-aged white people
Gjesing, A. P., Andersen, G., Borch-Johnsen, K., Jørgensen, T., Hansen, Torben & Pedersen, Oluf Borbye, 2008, In: Molecular Genetics and Metabolism. 94, 1, p. 90-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association of variants in the sterol regulatory element-binding factor 1 (SREBF1) gene with type 2 diabetes, glycemia, and insulin resistance: A study of 15,734 Danish subjects
Grarup, Niels, Stender-Petersen, K. L., Andersson, E. A., Jorgensen, T., Borch-Johnsen, K., Sandbaek, A., Lauritzen, T., Schmitz, O., Hansen, Torben & Pedersen, Oluf Borbye, 2008, In: Diabetes.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association of variants in the sterol regulatory element-binding factor 1 (SREBF1) gene with type 2 diabetes, glycemia, and insulin resistance: a study of 15,734 Danish subjects
Grarup, N., Stender-Petersen, K. L., Andersson, E. A., Jørgensen, T., Borch-Johnsen, K., Sandbæk, A., Lauritzen, T., Schmitz, O., Hansen, T. & Pedersen, Oluf Borbye, 2008, In: Diabetes. 57, 4, p. 1136-42 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association testing of novel type 2 diabetes risk alleles in the JAZF1, CDC123/CAMK1D, TSPAN8, THADA, ADAMTS9, and NOTCH2 loci with insulin release, insulin sensitivity, and obesity in a population-based sample of 4,516 glucose-tolerant middle-aged Danes.
Grarup, Niels, Andersen, G., Krarup, N. T., Albrechtsen, Anders, Schmitz, O., Jørgensen, T., Borch-Johnsen, K., Hansen, Torben & Pedersen, Oluf Borbye, 2008, In: Diabetes. 57, 9, p. 2534-40 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Autosomal inheritance of diabetes in two families characterized by obesity and a novel H241Q mutation in NEUROD1
Gonsorcíková, L., Pruhová, S., Cinek, O., Ek, J., Pelikánová, T., Jørgensen, T., Eiberg, Hans Rudolf Lytchoff, Pedersen, Oluf Borbye, Hansen, T. & Lebl, J., 2008, In: Pediatric Diabetes. 9, 4 Pt 2, p. 367-72 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Common nonsynonymous variants in PCSK1 confer risk of obesity.
Benzinou, M., Creemers, J. W. M., Choquet, H., Lobbens, S., Dina, C., Durand, E., Guerardel, A., Boutin, P., Jouret, B., Heude, B., Balkau, B., Tichet, J., Marre, M., Potoczna, N., Horber, F., Le Stunff, C., Czernichow, S., Sandbæk, A., Lauritzen, T., Borch-Johnsen, K. & 12 others, , 2008, In: Nature Genetics. 40, 8, p. 943-5 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cost-effectiveness of intensified versus conventional multifactorial intervention in type 2 diabetes: results and projections from the Steno-2 study
Gaede, P., Valentine, W. J., Palmer, A. J., Tucker, D. M. D., Lammert, M., Parving, H. & Pedersen, Oluf Borbye, 2008, In: Diabetes Care. 31, 8, p. 1510-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of a multifactorial intervention on mortality in type 2 diabetes
Gaede, P., Lund-Andersen, H., Parving, H. & Pedersen, Oluf Borbye, 2008, In: New England Journal of Medicine. 358, 6, p. 580-91 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of treatment with glucagon-like peptide-2 on bone resorption in colectomized patients with distal ileostomy or jejunostomy and short-bowel syndrome
Gottschalck, I. B., Jeppesen, Palle Bekker, Hartmann, Bolette, Holst, Jens Juul & Henriksen, D. B., 2008, In: Scandinavian Journal of Gastroenterology. 43, 11, p. 1304-10 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Endocannabinoid receptor 1 gene variations increase risk for obesity and modulate body mass index in European populations
Benzinou, M., Chèvre, J., Ward, K. J., Lecoeur, C., Dina, C., Lobbens, S., Durand, E., Delplanque, J., Horber, F. F., Heude, B., Balkau, B., Borch-Johnsen, K., Jørgensen, T., Hansen, T., Pedersen, Oluf Borbye, Meyre, D. & Froguel, P., 2008, In: Human Molecular Genetics. 17, 13, p. 1916-21 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
FTO gene associated fatness in relation to body fat distribution and metabolic traits throughout a broad range of fatness
Kring, S. I. I., Holst, C., Zimmermann, E., Jess, T., Berentzen, T., Toubro, S., Hansen, Torben, Astrup, A., Pedersen, Oluf Borbye & Sørensen, Thorkild I.A., 2008, In: PLoS ONE. 3, 8, p. e2958 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic analysis of Kruppel-like zinc finger 11 variants in 5864 Danish individuals: potential effect on insulin resistance and modified signal transducer and activator of transcription-3 binding by promoter variant -1659G>C
Gutiérrez-Aguilar, R., Froguel, P., Hamid, Y. H., Benmezroua, Y., Jørgensen, T., Borch-Johnsen, K., Hansen, T., Pedersen, Oluf Borbye & Neve, B., 2008, In: Journal of Clinical Endocrinology and Metabolism. 93, 8, p. 3128-35 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetikken ved ikkeautoimmun diabetes. Dansk Endokrinologisk Selskab
Hansen, T., Pedersen, Oluf Borbye & Dansk Endokrinologisk Selskab, D. E. S., 2008, In: Ugeskrift for læger. 170, 12, p. 1021Research output: Contribution to journal › Review › Research
- Published
Genotype-phenotype associations in obesity dependent on definition of the obesity phenotype
Kring, S. I. I., Larsen, L. H., Holst, C., Toubro, S., Hansen, Torben, Astrup, A., Pedersen, Oluf Borbye & Sørensen, Thorkild I.A., 2008, In: Obesity Facts. 1, 3, p. 138-145 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of TCF7L2 rs7903146 on insulin secretion and action in young and elderly Danish twins.
Wegner, L., Hussain, M. S., Pilgaard, K., Hansen, T., Pedersen, Oluf Borbye, Vaag, Allan & Poulsen, I. P., 2008, In: Journal of Clinical Endocrinology and Metabolism. 93, 10, p. 4013-9 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of metformin versus repaglinide on non-glycaemic cardiovascular risk markers related to inflammation and endothelial dysfunction in non-obese patients with type 2 diabetes
Lund, S. S., Tarnow, L., Stehouwer, C. D. A., Schalkwijk, C. G., Teerlink, T., Gram, J., Winther, K., Frandsen, M., Smidt, U. M., Pedersen, Oluf Borbye, Parving, H. & Vaag, Allan, 2008, In: European Journal of Endocrinology. 158, 5, p. 631-41 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of metformin versus the prandial insulin secretagogue, repaglinide, on fasting and postprandial glucose and lipid responses in non-obese patients with type 2 diabetes
Lund, S. S., Tarnow, L., Frandsen, M., Smidt, U. M., Pedersen, Oluf Borbye, Parving, H. & Vaag, Allan, 2008, In: European Journal of Endocrinology. 158, 1, p. 35-46 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of polymorphisms in WFS1 on prediabetic phenotypes in a population-based sample of middle-aged people with normal and abnormal glucose regulation
Sparsø, T., Andersen, G., Albrechtsen, Anders, Jørgensen, T., Borch-Johnsen, K., Sandbaek, A., Lauritzen, T., Wasson, J., Permutt, M. A., Glaser, B., Madsbad, Sten, Pedersen, Oluf Borbye & Hansen, Torben, 2008, In: Diabetologia. 51, 9, p. 1646-52 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact on weight dynamics and general growth of the common FTO rs9939609: a longitudinal Danish cohort study
Jess, T., Zimmermann, E., Kring, S. I. I., Berentzen, T., Holst, C., Toubro, S., Astrup, A., Hansen, Torben, Pedersen, O., Sørensen, Thorkild I.A. & Pedersen, Oluf Borbye, 2008, In: International Journal of Obesity. 32, 9, p. 1388-94 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impaired fasting glycaemia vs impaired glucose tolerance: similar impairment of pancreatic alpha and beta cell function but differential roles of incretin hormones and insulin action
Faerch, K., Vaag, Allan, Holst, Jens Juul, Glümer, C., Pedersen, Oluf Borbye & Borch-Johnsen, K., 2008, In: Diabetologia. 51, 5, p. 853-61 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Implicit knowledge of visual uncertainty guides decisions with asymmetric outcomes
Whiteley, Louise & Sahani, M., 2008, In: Journal of Vision. 8, 3, p. 2.1-15Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increased recovery rates of phosphocreatine (PCr) and inorganic phosphate (Pi) after isometric contraction in oxidative muscle fibres and elevated hepatic insulin resistance in carriers of the fat mass and obesity-associated FTO genotypes
Grunnet, Louise Groth, Brøns, C., Jacobsen, S., Nielsen, E., Astrup, A., Hansen, T., Pedersen, Oluf Borbye, Poulsen, P., Quistorff, B. & Vaag, A., 2008, In: Diabetes. 57, Suppl. 1, p. A329 1 p.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Insulin sensitivity, insulin release and glucagon-like peptide-1 levels in persons with impaired fasting glucose and/or impaired glucose tolerance in the EUGENE2 study
Laakso, M., Zilinskaite, J., Hansen, Torben, Boesgaard, T. W., Vänttinen, M., Stancáková, A., Jansson, P., Pellmé, F., Kuulasmaa, T., Hribal, M. L., Sesti, G., Stefan, N., Fritsche, A., Häring, H., Pedersen, Oluf Borbye, Smith, U., EUGENE2 Consortium, E. C. & Holst, Jens Juul, 2008, In: Diabetologia. 51, 3, p. 502-11 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lack of association between PKLR rs3020781 and NOS1AP rs7538490 and type 2 diabetes, overweight, obesity and related metabolic phenotypes in a Danish large-scale study: case-control studies and analyses of quantitative traits
Andreasen, C. H., Mogensen, M. S., Borch-Johnsen, K., Sandbæk, A., Lauritzen, T., Almind, K., Pedersen, Oluf Borbye, Hansen, L., Jørgensen, T. & Hansen, Torben, 2008, In: BMC Medical Genetics. 9, p. 118Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lack of association of fatness-related FTO gene variants with energy expenditure or physical activity
Berentzen, T., Kring, S. I. I., Holst, C., Zimmermann, E., Jess, T., Hansen, T., Pedersen, Oluf Borbye, Toubro, S., Astrup, A. & Sørensen, Thorkild I.A., 2008, In: Journal of Clinical Endocrinology and Metabolism. 93, 7, p. 2904-2908 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Low physical activity accentuates the effect of the FTO rs9939609 polymorphism on body fat accumulation
Andreasen, C. H., Stender-Petersen, K. L., Mogensen, M. S., Torekov, Signe Sørensen, Wegner, L., Andersen, G., Nielsen, A. L., Albrechtsen, Anders, Borch-Johnsen, K., Rasmussen, S. S., Clausen, J. O., Sandbaek, A., Lauritzen, T., Hansen, L., Jørgensen, T., Pedersen, Oluf Borbye & Hansen, T., 2008, In: Diabetes. 57, 1, p. 95-101 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Many sequence variants affecting diversity of adult human height
Gudbjartsson, D. F., Walters, G. B., Thorleifsson, G., Stefansson, H., Halldorsson, B. V., Zusmanovich, P., Sulem, P., Thorlacius, S., Gylfason, A., Steinberg, S., Helgadottir, A., Ingason, A., Steinthorsdottir, V., Olafsdottir, E. J., Olafsdottir, G. H., Jonsson, T., Borch-Johnsen, K., Hansen, T., Andersen, G., Jørgensen, T. & 17 others, , 2008, In: Nature Genetics. 40, 5, p. 609-15 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes
Zeggini, E., Scott, L. J., Saxena, R., Voight, B. F., Marchini, J. L., Hu, T., de Bakker, P. I. W., Abecasis, G. R., Almgren, P., Andersen, G., Ardlie, K., Boström, K. B., Bergman, R. N., Bonnycastle, L. L., Borch-Johnsen, K., Burtt, N. P., Chen, H., Chines, P. S., Daly, M. J., Deodhar, P. & 31 others, , 2008, In: Nature Genetics. 40, 5, p. 638-45 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
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Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets
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Family and population-based studies of variation within the ghrelin receptor locus in relation to measures of obesity
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