Novo Nordisk Foundation Center for Basic Metabolic Research

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  1. Published

    Diabetic cats have decreased gut microbial diversity and a lack of butyrate producing bacteria

    Kieler, Ida Nordang, Osto, M., Hugentobler, L., Puetz, Lara Christine, Gilbert, M Thomas P, Hansen, Torben, Pedersen, Oluf Borbye, Reusch, C. E., Zini, E., Lutz, T. A. & Bjørnvad, Charlotte Reinhard, 2019, In: Scientific Reports. 9, p. 1-13 13 p., 4822.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Diabetic intestinal growth adaptation and glucagon-like peptide 2 in the rat: effects of dietary fibre

    Thulesen, J., Hartmann, Bolette, Nielsen, C., Holst, Jens Juul & Poulsen, Steen Seier, Nov 1999, In: Gut. 45, 5, p. 672-8 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Diabetologia at 50: celebrating half a century of progress in diabetes research and care

    Zierath, Juleen R, Aug 2015, In: Diabetologia. 58, 8, p. 1685-7 3 p.

    Research output: Contribution to journal › Editorial › Research › peer-review

  4. Published

    Diagnostik og behandling af maturity onset diabetes of the young type 3

    Rose, K., Christensen, A. S., Storgaard, H., Hædersdal, S., Hansen, Torben, Knop, Filip Krag & Vilsbøll, Tina, 2018, In: Ugeskrift for Laeger. 180, 6 p., V06170502.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Diet-microbiota interactions as moderators of human metabolism

    Sonnenburg, J. L. & Bäckhed, G. F., 7 Jul 2016, In: Nature. 535, 7610, p. 56-64 9 p.

    Research output: Contribution to journal › Review › Research › peer-review

  6. Published

    Dietary n-6 PUFA, carbohydrate: protein ratio and change in body weight and waist circumference: a follow-up study

    Jakobsen, M. U., Madsen, L., Dethlefsen, C., Due, K. M., Halkjaer, J., Sørensen, Thorkild I.A., Kristiansen, Karsten & Overvad, K., 2015, In: Public Health Nutrition. 18, 07, p. 1317-1323 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Dietary Assessment in the MetaCardis Study: Development and Relative Validity of an Online Food Frequency Questionnaire

    Verger, E. O., Armstrong, P., Nielsen, T., Chakaroun, R., Aron-Wisnewsky, J., Gøbel, R. J., Schütz, T., Delaere, F., Gausseres, N., Clément, K., Holmes, B. A. & MetaCardis Consortium, M. C., Jun 2017, In: Journal of the Academy of Nutrition and Dietetics. 117, 6, p. 878-888 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Dietary Fat and the Genetic Risk of Type 2 Diabetes

    Carrasquilla, Germán D., Jakupovic, Hermina & Kilpeläinen, Tuomas O., 2019, In: Current Diabetes Reports. 19, 6 p., 109.

    Research output: Contribution to journal › Review › Research › peer-review

  9. Published

    Dietary Fiber Is Essential to Maintain Intestinal Size, L-Cell Secretion, and Intestinal Integrity in Mice

    Dal, Jenna Elizabeth Hunt, Hartmann, Bolette, Schoonjans, K., Holst, Jens Juul & Kissow, Hannelouise, 2021, In: Frontiers in Endocrinology. 12, 10 p., 640602.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Dietary Fiber is Essential to Maintain L Cell Secretion and Intestinal Weight

    Dal, Jenna Elizabeth Hunt, Hartmann, Bolette, Holst, Jens Juul & Kissow, Hannelouise, 1 May 2019, In: Gastroenterology. 156, 6 (S1), p. S-477

    Research output: Contribution to journal › Conference abstract in journal › Research

  11. Published

    Dietary Fiber-Induced Improvement in Glucose Metabolism Is Associated with Increased Abundance of Prevotella

    Kovatcheva-Datchary, P., Nilsson, A., Akrami, R., Lee, Y. S., De Vadder, F., Arora, T., Hallen, A., Martens, E., Björck, I. & Bäckhed, G. F., 1 Dec 2015, In: Cell Metabolism. 22, 6, p. 971-82 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Dietary Protein Restriction Improves Metabolic Dysfunction in Patients with Metabolic Syndrome in a Randomized, Controlled Trial

    Ferraz-Bannitz, R., Beraldo, R. A., Peluso, A., Dall, M., Babaei, P., Foglietti, R. C., Martins, L. M., Gomes, P. M., Marchini, J. S., Miguel Suen, V. M., Conti de Freitas, L. C., Navegantes, L. C., Pretti, M. A. M., Boroni, M., Treebak, Jonas Thue, Mori, M. A., Foss, M. C. & Foss-Freitas, M. C., 2022, In: Nutrients. 14, 13, 18 p., 2670.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Dietary ascorbic acid and subsequent change in body weight and waist circumference: associations may depend on genetic predisposition to obesity - a prospective study of three independent cohorts

    Larsen, S. C., Ängquist, Lars, Ahluwalia, Tarun Veer Singh, Skaaby, T., Roswall, N., Tjønneland, A., Halkjær, J., Overvad, K., Pedersen, Oluf Borbye, Hansen, Torben, Linneberg, Allan René, Husemoen, L. L. N., Toft, Ulla Marie Nørgaard, Heitmann, B. L. & Sørensen, Thorkild I.A., 2014, In: Nutrition Journal. 13, p. 1-11 11 p., 43.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Dietary carbohydrate restriction augments weight loss-induced improvements in glycaemic control and liver fat in individuals with type 2 diabetes: A randomised controlled trial

    Thomsen, M. N., Skytte, M. J., Samkani, A., Carl, M. H., Weber, P., Astrup, A., Chabanova, E., Fenger, M., Frystyk, J., Hartmann, Bolette, Holst, Jens Juul, Larsen, T. M., Madsbad, Sten, Magkos, Faidon, Thomsen, Henrik S., Haugaard, Steen Bendix & Krarup, T., 2022, In: Diabetologia. 65, p. 506-517 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Dietary determinants of changes in waist circumference adjusted for body mass index - a proxy measure of visceral adiposity

    Romaguera, D., Ängquist, Lars, Du, H., Jakobsen, M. U., Forouhi, N. G., Halkjaer, J., Feskens, E. J. M., van der A, D. L., Masala, G., Steffen, A., Palli, D., Wareham, N. J., Overvad, K., Tjønneland, A., Boeing, H., Riboli, E. & Sørensen, Thorkild I.A., 1 Jan 2010, In: P L o S One. 5, 7, p. e11588

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Dietary fat drives whole-body insulin resistance and promotes intestinal inflammation independent of body weight gain

    Jensen, Benjamin Anderschou Holbech, Nielsen, Thomas Svava, Fritzen, Andreas Mæchel, Holm, J. B., Fjære, E., Serup, A. K. L., Borkowski, K., Risis, S., Pærregaard, S. I., Søgaard, I., Poupeau, A. A. G., Poulsen, M., Ma, Tao, Sina, C., Kiens, Bente, Madsen, L., Kristiansen, Karsten & Treebak, Jonas Thue, 2016, In: Metabolism. 65, 12, p. 1706-1719 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Dietary fatty acid composition drives neuroinflammation and impaired behavior in obesity

    Sanchez, C., Colson, C., Gautier, N., Noser, Pascal, Salvi, J., Villet, M., Fleuriot, L., Peltier, C., Schlich, P., Brau, F., Sharif, A., Altıntaş, Ali, Amri, E. Z., Nahon, J. L., Blondeau, N., Benani, A., Barrès, Romain & Rovère, C., 2024, In: Brain, Behavior, and Immunity. 117, p. 330-346 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Dietary fiber and subsequent changes in body weight and waist circumference in European men and women

    Du, H., van der A, D. L., Boshuizen, H. C., Forouhi, N. G., Wareham, N. J., Halkjaer, J., Tjønneland, A., Overvad, K., Jakobsen, M. U., Boeing, H., Buijsse, B., Masala, G., Palli, D., Sørensen, Thorkild I.A., Saris, W. H. M. & Feskens, E. J. M., 1 Feb 2010, In: American Journal of Clinical Nutrition. 91, 2, p. 329-36 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Dietary impact on fasting and stimulated GLP-1 secretion in different metabolic conditions - a narrative review

    Huber, H., Schieren, A., Holst, Jens Juul & Simon, M., 2024, In: The American Journal of Clinical Nutrition. 119, 3, p. 599-627

    Research output: Contribution to journal › Review › Research › peer-review

  20. Published

    Dietary intake and adipose tissue content of long-chain n-3 PUFAs and subsequent 5-y change in body weight and waist circumference

    Jakobsen, M. U., Madsen, L., Skjøth, F., Berentzen, T. L., Halkjaer, J., Tjønneland, A., Schmidt, E. B., Sørensen, Thorkild I.A., Kristiansen, Karsten & Overvad, K., May 2017, In: The American Journal of Clinical Nutrition. 105, 5, p. 1148-1157 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Dietary intake, FTO genetic variants and adiposity: a combined analysis of over 16,000 children and adolescents

    Qi, Q., Downer, M. K., Oskari Kilpeläinen, T., Taal, H. R., Barton, S. J., Ntalla, I., Standl, M., Boraska, V., Huikari, V., Kiefte-de Jong, J. C., Körner, A., Lakka, T. A., Liu, G., Magnusson, J., Okuda, M., Raitakari, O., Richmond, R., Scott, R. A., Bailey, M. E. S., Scheuermann, K. & 22 others, Holloway, J. W., Inskip, H., Isasi, C. R., Mossavar-Rahmani, Y., Jaddoe, V. W. V., Laitinen, J., Lindi, V., Melén, E., Pitsiladis, Y., Pitkänen, N., Snieder, H., Heinrich, J., Timpson, N. J., Wang, T., Yuji, H., Zeggini, E., Dedoussis, G. V., Kaplan, R. C., Wylie-Rosett, J., Loos, R. J. F., Hu, F. B. & Qi, L., Jul 2015, In: Diabetes. 64, 7, p. 2467-76 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Dietary intervention modulates the gut microbiota and improves insulin resistance - a randomized controlled trial in obese postmenopausal women

    Brahe, L. K., Le Chatelier, E., Prifti, E., Kennedy, S., Blædel, T., Håkansson, J., Pedersen, Oluf Borbye, Astrup, A., Ehrlich, S. & Larsen, L. H., 2014, In: Obesity Reviews. 15, Suppl. 2, p. 41-42 2 p.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  23. Published

    Dietary leucine--an environmental modifier of insulin resistance acting on multiple levels of metabolism

    Macotela, Y., Emanuelli, Brice, Bång, A. M., Espinoza, D. O., Boucher, J., Beebe, K., Gall, W. & Kahn, C. R., 2011, In: PLOS ONE. 6, 6, p. e21187

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Dietary macronutrient composition impacts gene regulation in adipose tissue

    Farris, K. M., Senior, A. M., Sobreira, D. R., Mitchell, R. M., Weber, Z. T., Ingerslev, L. R., Barrès, Romain, Simpson, S. J., Crean, A. J. & Nobrega, M. A., 2024, In: Communications Biology . 7, 13 p., 194.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Dietary medium-chain fatty acids reduce food intake via the GDF15-GFRAL axis in mice

    Kanta, Josephine Maria, Deisen, L., Johann, K., Holm, Stephanie Kjærulff, Lundsgaard, Anne-Marie, Lund, Jens, Jähnert, M., Schürmann, A., Clemmensen, Christoffer, Kiens, Bente, Fritzen, Andreas Mæchel & Kleinert, Maximilian, 2023, In: Molecular Metabolism. 74, 10 p., 101760.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Dietary metabolite profiling brings new insight into the relationship between nutrition and metabolic risk: An IMI DIRECT study

    Eriksen, R., Perez, I. G., Posma, J. M., Haid, M., Sharma, S., Prehn, C., Thomas, L. E., Koivula, R. W., Bizzotto, R., Prehn, C., Mari, A., Giordano, G. N., Pavo, I., Schwenk, J. M., De Masi, F., Tsirigos, K. D., Brunak, S., Viñuela, A., Mahajan, A., McDonald, T. J. & 18 others, Kokkola, T., Rutter, F., Teare, H., Hansen, T. H., Fernandez, J., Jones, A., Jennison, C., Walker, M., McCarthy, M. I., Pedersen, Oluf Borbye, Ruetten, H., Forgie, I., Bell, J. D., Pearson, E. R., Franks, P. W., Adamski, J., Holmes, E. & Frost, G., Aug 2020, In: EBioMedicine. 58, p. 102932

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Dietary modulation of the gut microbiota - a randomised controlled trial in obese postmenopausal women

    Brahe, L. K., Le Chatelier, E., Prifti, E., Pons, N., Kennedy, S., Blædel, T., Håkansson, J., Dalsgaard, T. K., Hansen, Torben, Pedersen, Oluf Borbye, Astrup, A., Ehrlich, S. D. & Larsen, L. H., 2015, In: British Journal of Nutrition. 114, 3, p. 406-417 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Dietary patterns predict changes in two-hour post-oral glucose tolerance test plasma glucose concentrations in middle-aged adults

    Lau, C., Toft, U., Tetens, Inge , Carstensen, Bendix, Jørgensen, T., Pedersen, Oluf Borbye & Borch-Johnsen, K., 2009, In: Journal of Nutrition. 139, 3, p. 588-593 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Dietary protein and subsequent 6-year change in fat and fat free mass

    Ankarfeldt, M. Z., Gottliebsen, K., Heitmann, B. L., Astrup, A. & Sørensen, Thorkild I.A., 2013, In: Obesity Facts. 6, suppl. 1, p. 34 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  30. Published

    Dietary protein and urinary nitrogen in relation to 6-year changes in fat mass and fat-free mass

    Ankarfeldt, Mikkel Zöllner, Gottliebsen, K., Ängquist, Lars, Astrup, A., Heitmann, Berit & Sørensen, Thorkild I.A., 2015, In: International Journal of Obesity. 39, 1, p. 162-168 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Dietary sucrose induces metabolic inflammation and atherosclerotic cardiovascular diseases more than dietary fat in LDLr−/− ApoB100/100 mice

    Perazza, L. R., Mitchell, P. L., Jensen, Benjamin Anderschou Holbech, Daniel, N., Boyer, M., Varin, T. V., Bouchareb, R., Nachbar, R. T., Bouchard, M., Blais, M., Gagné, A., Joubert, P., Sweeney, G., Roy, D., Arsenault, B. J., Mathieu, P. & Marette, A., 2020, In: Atherosclerosis. 304, p. 9-21 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Difference in postprandial GLP-1 response despite similar glucose kinetics after consumption of wheat breads with different particle size in healthy men

    Eelderink, C., Noort, M. W. J., Sozer, N., Koehorst, M., Holst, Jens Juul, Deacon, Carolyn F., Rehfeld, Jens Frederik, Poutanen, K., Vonk, R. J., Oudhuis, L. & Priebe, M. G., 2017, In: European Journal of Nutrition. 56, 3, p. 1063-1076 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Differences in genetic and environmental variation in adult BMI by sex, age, time period, and region: an individual-based pooled analysis of 40 twin cohorts

    Silventoinen, K., Jelenkovic, A., Sund, R., Yokoyama, Y., Hur, Y-M., Cozen, W., Hwang, A. E., Mack, T. M., Honda, C., Inui, F., Iwatani, Y., Watanabe, M., Tomizawa, R., Pietiläinen, K. H., Rissanen, A., Siribaddana, S. H., Hotopf, M., Sumathipala, A., Rijsdijk, F., Tan, Q. & 82 others, Zhang, D., Pang, Z., Piirtola, M., Aaltonen, S., Öncel, S. Y., Aliev, F., Rebato, E., Hjelmborg, J. B., Christensen, K., Skytthe, A., Kyvik, K. O., Silberg, J. L., Eaves, L. J., Cutler, T. L., Ordoñana, J. R., Sánchez-Romera, J. F., Colodro-Conde, L., Song, Y., Yang, S., Lee, K., Franz, C. E., Kremen, W. S., Lyons, M. J., Busjahn, A., Nelson, T. L., Whitfield, K. E., Kandler, C., Jang, K. L., Gatz, M., Butler, D. A., Stazi, M. A., Fagnani, C., D'Ippolito, C., Duncan, G. E., Buchwald, D., Martin, N. G., Medland, S. E., Montgomery, G. W., Jeong, H., Swan, G. E., Krasnow, R., Magnusson, P. K., Pedersen, N. L., Dahl Aslan, A. K., McAdams, T. A., Eley, T. C., Gregory, A. M., Tynelius, P., Baker, L. A., Tuvblad, C., Bayasgalan, G., Narandalai, D., Spector, T. D., Mangino, M., Lachance, G., Burt, S. A., Klump, K. L., Harris, J. R., Brandt, I., Nilsen, T. S., Krueger, R. F., McGue, M., Pahlen, S., Corley, R. P., Huibregtse, B. M., Bartels, M., van Beijsterveldt, C. E., Willemsen, G., Goldberg, J. H., Rasmussen, F., Tarnoki, A. D., Tarnoki, D. L., Derom, C. A., Vlietinck, R. F., Loos, R. J., Hopper, J. L., Sung, J., Maes, H. H., Turkheimer, E., Boomsma, D. I., Sørensen, Thorkild I.A. & Kaprio, J., Aug 2017, In: The American Journal of Clinical Nutrition. 106, 2, p. 457-466 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Different Malabsorptive Obesity Surgery Interventions Result in Distinct Postprandial Amino Acid Metabolomic Signatures

    Pereira, S. S., Jarak, I., Carvalho, R. A., Oliveira, P. F., Alves, M. G., Guimaraes, M., Almeida, R., Pereira, A. M., Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Nora, M. & Monteiro, M. P., 2020, In: Obesity Surgery. 30, p. 4019-4028

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Different molecular events result in low protein levels of mannan-binding lectin in populations from southeast Africa and South America

    Madsen, H. O., Satz, M. L., Høgh, Birthe, Svejgaard, A. & Garred, Peter, 15 Sep 1998, In: Journal of immunology (Baltimore, Md. : 1950). 161, 6, p. 3169-75 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Differential Brain and Cerebrospinal Fluid Proteomic Responses to Acute Prenatal Endotoxin Exposure

    Muk (Mudi), Tik, Stensballe, A., Dmytriyeva, O., Brunse, Anders, Jiang, Pingping, Thymann, Thomas, Sangild, Per Torp & Pankratova, Stanislava, 2022, In: Molecular Neurobiology. 59, p. 2204–2218

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Differential Effects of Secretin-fragments imply a dual Mechanism of Action for Secretin

    Kofod, H., Thams, P. & Holst, Jens Juul, Feb 1991, In: International Journal of Peptide and Protein Research. 37, 2, p. 134-139 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Differential action of TGR5 agonists on GLP-2 secretion and promotion of intestinal adaptation in a piglet short bowel model

    Lin, S., Stoll, B., Robinson, J., Pastor, J. J., Marini, J. C., Ipharraguerre, I. R., Hartmann, Bolette, Holst, Jens Juul, Cruz, S., Lau, P., Olutoye, O., Fang, Z. & Burrin, D. G., May 2019, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 316, 5, p. G641-G652

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Differential aetiology and impact of phosphoinositide 3-kinase (PI3K) and Akt signalling in skeletal muscle on in vivo insulin action

    Friedrichsen, M., Poulsen, P., Richter, Erik A., Hansen, B. F., Birk, Jesper Bratz, Ribel-Madsen, R., Stender-Petersen, K., Nilsson, E., Beck-Nielsen, H., Vaag, Allan & Wojtaszewski, Jørgen F P, 2010, In: Diabetologia. 53, 9, p. 1998-2007 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Differential and shared genetic effects on kidney function between diabetic and non-diabetic individuals

    Winkler, T. W., Rasheed, H., Teumer, A., Gorski, M., Rowan, B. X., Stanzick, K. J., Thomas, L. F., Tin, A., Hoppmann, A., Chu, A. Y., Tayo, B., Thio, C. H. L., Cusi, D., Chai, J-F., Sieber, K. B., Horn, K., Li, M., Scholz, M., Cocca, M., Wuttke, M. & 31 others, van der Most, P. J., Yang, Q., Ghasemi, S., Nutile, T., Li, Y., Pontali, G., Günther, F., Dehghan, A., Correa, A., Parsa, A., Feresin, A., de Vries, A. P. J., Zonderman, A. B., Smith, A. V., Oldehinkel, A. J., De Grandi, A., Rosenkranz, A. R., Franke, A., Teren, A., Metspalu, A., Hicks, A. A., Morris, A. P., Tönjes, A., Morgan, A., Podgornaia, A. I., Christensen, K., Lind, L., Kovacs, P., Rossing, Peter, Loos, Ruth & LifeLines Cohort Study, L. C. S., 2022, In: Communications Biology . 5, p. 580 20 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Differential effects of bile acids on the postprandial secretion of gut hormones: A randomized crossover study

    McGlone, E. R., Malallah, K., Cuenco, J., Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Vincent, R. P., Ling, C., Khan, O. A., Verma, S., Ahmed, A. R., Walters, J. R. F., Khoo, B., Bloom, S. R. & Tan, T. M. M., 2021, In: American Journal of Physiology - Endocrinology and Metabolism. 320, 4, p. E671-E679

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Differential effects of glucagon-like peptide-1 on microvascular recruitment and glucose metabolism in short- and long-term Insulin resistance

    Sjøberg, K. A., Rattigan, S., Jeppesen, J. F., Lundsgaard, Anne-Marie, Holst, Jens Juul & Kiens, Bente, 2015, In: Journal of Physiology. 593, 9, p. 2185-2198 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Differential impact of glucose administered intravenously or orally on bone turnover markers in healthy male subjects

    Westberg-Rasmussen, S., Starup-Linde, J., Hermansen, K., Holst, Jens Juul, Hartmann, Bolette, Vestergaard, P. & Gregersen, S., Apr 2017, In: Bone. 97, p. 261-266 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Differential incretin effects of GIP and GLP-1 on gastric emptying, appetite, and insulin-glucose homeostasis

    Edholm, T., Degerblad, M., Grybäck, P., Hilsted, Linda, Holst, Jens Juul, Jacobsson, H., Efendic, S., Schmidt, P. T. & Hellström, P. M., 1 Nov 2010, In: Neurogastroenterology and Motility Online. 22, 11, p. 1191-200, e315 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Differential regulation of lipid and protein metabolism in obese vs. lean subjects before and after a 72-h fast

    Bak, A. M., Møller, A. B., Vendelbo, M. H., Nielsen, Thomas Svava, Viggers, R., Rungby, Jørgen, Pedersen, S. B., Jørgensen, J. O. L., Jessen, N. & Møller, N., 1 Jul 2016, In: American Journal of Physiology: Endocrinology and Metabolism. 311, 1, p. E224-35 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Differential time responses in inflammatory and oxidative stress markers after a marathon: An observational study

    Larsen, E. L., Poulsen, Henrik Enghusen, Michaelsen, C., Kjær, L. K., Lyngbæk, M., Andersen, Emilie Skytte, Petersen-Bønding, C., Lemoine, C., Gillum, M., Jørgensen, Niklas Rye, Ploug, Thorkil, Vilsbøll, Tina, Knop, Filip Krag & Karstoft, K., 2020, In: Journal of Sports Sciences. 38, 18, p. 2080-2091

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Digital questionnaire platform in the Danish Blood Donor Study

    Burgdorf, K. S., Felsted, N., Mikkelsen, S., Nielsen, Maria Haahr, Thørner, L. W., Pedersen, Oluf Borbye, Sørensen, E., Nielsen, K. R., Bruun, M. T., Werge, Thomas, Erikstrup, C., Hansen, T. & Ullum, H., 12 Jul 2016, In: Computer Methods and Programs in Biomedicine. 135, p. 101-104 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Diminishing benefits of urban living for children and adolescents’ growth and development

    Mishra, A., Zhou, B., Rodriguez-Martinez, A., Bixby, H., Baker, J. L., Afzal, S., Allin, K., Andersen, L. B., Ängquist, L., Jørgensen, M. B., Bjerregaard, P., Bojesen, S. E., Christensen, K., Damsgaard, C. T., Dantoft, T. M., Eliasen, M., Eriksen, L., Halkjær, J., Giwercman, A., Jørgensen, T. & 19 others, Kristensen, P. L., Lind, L., Linneberg, Allan René, Madsen, A. L., Michaelsen, Kim F., Møllehave, Line Tang, Mortensen, Erik Lykke, Nordestgaard, Børge, Osler, Merete, Overvad, K., Schmidt, I. M., Schnohr, P., Schramm, S., Sodemann, M., Sørensen, Thorkild I.A., Tjønneland, Anne, Tolstrup, J. S., Wang, Q. & NCD Risk Factor Collaboration (NCD-RisC), N. R. F. C. (., 2023, In: Nature. 615, 7954, p. 874-883 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Dipeptidyl peptidase IV inhibition enhances the intestinotrophic effect of glucagon-like peptide-2 in rats and mice

    Hartmann, Bolette, Thulesen, J., Kissow, Hannelouise, Thulesen, S., Ørskov, Cathrine, Ropke, C., Poulsen, Steen Seier & Holst, Jens Juul, 2000, In: Endocrinology. 141, 11, p. 4013-20 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Dipeptidyl peptidase IV inhibition potentiates the insulinotropic effect of glucagon-like peptide 1 in the anesthetized pig.

    Deacon, Carolyn F., Hughes, T. E. & Holst, Jens Juul, 1998, In: Diabetes. 47, p. 764-769

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    Dipeptidyl peptidase IV resistant analogues of glucagon-like peptide-1 which have extended metabolic stability and improved biological activity

    Deacon, Carolyn F., Knudsen, L. B., Madsen, K., Wiberg, F. C., Jacobsen, O. & Holst, Jens Juul, 1998, In: Diabetologia. 41, p. 271-278

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Dipeptidyl peptidase-4 inhibition increases portal concentrations of intact glucagon-like peptide-1 (GLP-1) to a greater extent than peripheral concentrations in anaesthetised pigs

    Hjøllund, K. R., Deacon, Carolyn F. & Holst, Jens Juul, 2011, In: Diabetologia. 54, 8, p. 2206-8 3 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  53. Published

    Dipeptidyl peptidase-4 inhibitors administered in combination with metformin result in an additive increase in the plasma concentration of active GLP-1

    Migoya, E. M., Bergeron, R., Miller, J. L., Snyder, R. N. K., Tanen, M., Hilliard, D., Weiss, B., Larson, P., Gutierrez, M., Jiang, G., Liu, F., Pryor, K. A., Yao, J., Zhu, L., Holst, J. J., Deacon, C., Herman, G., Thornberry, N., Amatruda, J., Williams-Herman, D. & 2 others, Wagner, J. A. & SinhaRoy, R., 1 Dec 2010, In: Clinical Pharmacology and Therapeutics. 88, 6, p. 801-8 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    Dipeptidyl peptidase-4 inhibitors for the treatment of type 2 diabetes: comparison, efficacy and safety

    Deacon, Carolyn F. & Holst, Jens Juul, Oct 2013, In: Expert Opinion on Pharmacotherapy. 14, 15, p. 2047-58 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  55. Published

    Direct ChIP-bisulfite sequencing reveals a role of H3K27me3 mediating aberrant hypermethylation of promoter CpG islands in cancer cells

    Gao, F., Ji, G., Gao, Z., Han, X., Ye, M., Yuan, Z., Luo, H., Huang, X., Natarajan, K., Wang, J., Yang, H. & Zhang, X., 2014, In: Genomics. 103, 2-3, p. 204-210 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  56. Published

    Direct assessment of hepatic mitochondrial oxidative and anaplerotic fluxes in humans using dynamic 13C magnetic resonance spectroscopy

    Befroy, D. E., Perry, R. J., Jain, N., Dufour, S., Cline, G. W., Trimmer, J. K., Brosnan, J., Rothman, D. L., Petersen, K. F. & Shulman, G. I., 2014, In: Nature Medicine. 20, 1, p. 98-102 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  57. Published

    Direct comparison of [18F]MH.MZ and [18F]altanserin for 5-HT2A receptor imaging with PET

    Hansen, H. D., Ettrup, A., Herth, Matthias Manfred, Dyssegaard, A., Ratner, C., Gillings, N. & Knudsen, G. M., 2013, In: Synapse. 67, 6, p. 328-337 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  58. Published

    Direct effects of FGF21 on glucose uptake in human skeletal muscle: implications for type 2 diabetes and obesity

    Mashili, F. L., Austin, R. L., Deshmukh, Atul Shahaji, Fritz, T., Caidahl, K., Bergdahl, K., Zierath, Juleen R, Chibalin, A. V., Moller, D. E., Kharitonenkov, A. & Krook, A., Mar 2011, In: Diabetes - Metabolism: Research and Reviews (Print Edition). 27, 3, p. 286-97 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  59. Published

    Directional dominance on stature and cognition in diverse human populations

    Joshi, P. K., Esko, T., Mattsson, H., Eklund, N., Gandin, I., Nutile, T., Jackson, A. U., Schurmann, C., Smith, A. V., Zhang, W., Okada, Y., Stančáková, A., Faul, J. D., Zhao, W., Bartz, T. M., Concas, M. P., Franceschini, N., Enroth, S., Vitart, V., Trompet, S. & 31 others, Guo, X., Chasman, D. I., O'Connel, J. R., Corre, T., Nongmaithem, S. S., Chen, Y., Mangino, M., Ruggiero, D., Traglia, M., Farmaki, A., Kacprowski, T., Bjonnes, A., van der Spek, A., Wu, Y., Giri, A. K., Yanek, L. R., Wang, L., Hofer, E., Rietveld, C. A., McLeod, O., Cornelis, M. C., Pattaro, C., Verweij, N., Baumbach, C., Abdellaoui, A., Warren, H. R., Ahluwalia, Tarun Veer Singh, Melbye, M., Bisgaard, H., Sørensen, Thorkild I.A. & BioBank Japan Project, B. J. P., 23 Jul 2015, In: Nature. 523, p. 459-62 4 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  60. Published

    Disassociation of bone resorption and formation by GLP-2: a 14-day study in healthy postmenopausal women

    Henriksen, D. B., Alexandersen, P., Hartmann, Bolette, Adrian, C. L., Byrjalsen, I., Bone, H. G., Holst, Jens Juul & Christiansen, C., Mar 2007, In: Bone. 40, 3, p. 723-9 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  61. Published

    Discovering Subgroups of Children With High Mortality in Urban Guinea-Bissau: Exploratory and Validation Cohort Study

    Rieckmann, Andreas, Nielsen, S., Dworzynski, P., Amini, H., Mogensen, S. W., Silva, I. B., Chang, A. Y., Arah, O. A., Samek, W., Rod, Naja Hulvej, Ekstrøm, Claus Thorn, Benn, C. S., Aaby, P. & Fisker, A. B., 2024, In: JMIR Public Health and Surveillance. 10, 16 p., e48060.

    Research output: Contribution to journal › Journal article › Research › peer-review

  62. Published

    Discovery and characterization of alamandine: A novel component of the renin-angiotensin system

    Lautner, R. Q., Villela, D. C., Fraga-Silva, R. A., Silva, N., Verano-Braga, T., Costa-Fraga, F., Jankowski, J., Jankowski, V., Sousa, F., Alzamora, A., Soares, E., Barbosa, C., Kjeldsen, F., Oliveira, A., Braga, J., Savergnini, S., Maia, G., Peluso, A. B., Passos-Silva, D., Ferreira, A. & 12 others, Alves, F., Martins, A., Raizada, M., Paula, R., Motta-Santos, D., Kemplin, F., Pimenta, A., Alenina, N., Sinisterra, R., Bader, M., Campagnole-Santos, M. J. & Santos, R. A. S., 12 Apr 2013, In: Circulation Research. 112, 8, p. 1104-1111 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  63. Published

    Discovery and uses of pegvisomant: A growth hormone antagonist

    Berryman, D. E., Palmer, A. J., Gosney, E. S., Swaminathan, S., DeSantis, D. & Kopchick, J. J., 1 Dec 2007, In: Endokrynologia Polska. 58, 4, p. 322-329 8 p.

    Research output: Contribution to journal › Review › Research › peer-review

  64. Published

    Discovery of GPR183 Agonists Based on an Antagonist Scaffold

    Kjær, Viktoria Madeline Skovgaard, Ieremias, L., Daugvilaite, V., Lückmann, Michael, Frimurer, Thomas Michael, Ulven, Trond, Rosenkilde, Mette & Våbenø, J., 2021, In: ChemMedChem. 16, 17, p. 2623-2627

    Research output: Contribution to journal › Journal article › Research › peer-review

  65. Published

    Discovery of a Potent Thiazolidine Free Fatty Acid Receptor 2 Agonist with Favorable Pharmacokinetic Properties

    Hansen, A. H., Sergeev, E., Bolognini, D., Sprenger, R. R., Ekberg, J. H., Ejsing, C. S., McKenzie, C. J., Ulven, Elisabeth Rexen, Milligan, G. & Ulven, Trond, 2018, In: Journal of Medicinal Chemistry. 61, 21, p. 9534-9550 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  66. Published

    Discovery of biomarkers for glycaemic deterioration before and after the onset of type 2 diabetes: descriptive characteristics of the epidemiological studies within the IMI DIRECT Consortium

    Koivula, R. W., Forgie, I. M., Kurbasic, A., Viñuela, A., Heggie, A., Giordano, G. N., Hansen, T. H., Hudson, M., Koopman, A. D. M., Rutters, F., Siloaho, M., Allin, K. H., Brage, S., Brorsson, C. A., Dawed, A. Y., De Masi, F., Groves, C. J., Kokkola, T., Mahajan, A., Perry, M. H. & 31 others, Rauh, S. P., Ridderstråle, M., Teare, H. J. A., Thomas, E. L., Tura, A., drb459, drb459, White, T., Adamski, J., Bell, J. D., Beulens, J. W., Brunak, Søren, Dermitzakis, E. T., Froguel, P., Frost, G., Gupta, R., Hansen, Torben, Hattersley, A., Jablonka, B., Kaye, J., Laakso, M., McDonald, T. J., Pedersen, Oluf Borbye, Schwenk, J. M., Pavo, I., Mari, A., McCarthy, M. I., Ruetten, H., Walker, M., Pearson, E., Franks, P. W. & IMI-DIRECT consortium, I. C., 2019, In: Diabetologia. 62, 9, p. 1601-1615

    Research output: Contribution to journal › Journal article › Research › peer-review

  67. Published

    Discovery of biomarkers for glycaemic deterioration before and after the onset of type 2 diabetes: rationale and design of the epidemiological studies within the IMI DIRECT Consortium: Diabetologia

    Koivula, R., Heggie, A., Barnett, A., Cederberg, H., Hansen, T. H., Koopman, A., Ridderstråle, M., Rutters, F., Vestergaard, H., Gupta, R., Herrgård, S., Heymans, M., Perry, M., Rauh, S., Siloaho, M., Teare, H. A., Thorand, B., Bell, J., Brunak, S., Frost, G. & 13 others, Jablonka, B., Mari, A., McDonald, T., Dekker, J., Hansen, Torben, Hattersley, A., Laakso, M., Pedersen, Oluf Borbye, Koivisto, V., Ruetten, H., Walker, M., Pearson, E. & Franks, P., 2014, In: Diabetologia. 57, 6, p. 1-11 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  68. Published

    Discovery of coding genetic variants influencing diabetes-related serum biomarkers and their impact on risk of type 2 diabetes

    Ahluwalia, Tarun Veer Singh, Allin, K. H., Sandholt, C. H., Sparsø, T. H., Jørgensen, M. E., Rowe, M., Christensen, C., Brandslund, I., Lauritzen, T., Linneberg, Allan René, Husemoen, L., Jørgensen, T., Hansen, Torben, Grarup, Niels & Pedersen, Oluf Borbye, Apr 2015, In: The Journal of clinical endocrinology and metabolism. 100, 4, p. E664-71

    Research output: Contribution to journal › Journal article › Research › peer-review

  69. Published

    Discovery of drug-omics associations in type 2 diabetes with generative deep-learning models: [with Author Correction]

    Allesøe, R. L., Lundgaard, A. T., Hernández Medina, R., Aguayo-Orozco, A., Johansen, J., Nissen, J. N., Brorsson, C., Mazzoni, G., Niu, L., Biel, J. H., Brasas, V., Webel, H., Benros, M. E., Pedersen, A. G., Chmura, P. J., Jacobsen, U. P., Mari, A., Koivula, R., Mahajan, A., Vinuela, A. & 31 others, Tajes, J. F., Sharma, S., Haid, M., Hong, M., Musholt, P. B., De Masi, F., Vogt, J., Pedersen, H. K., Gudmundsdottir, V., Jones, A., Kennedy, G., Bell, J., Thomas, E. L., Frost, G., Thomsen, Henrik S., Hansen, E., Hansen, T. H., drb459, drb459, Muilwijk, M., Blom, M. T., 't Hart, L. M., Pattou, F., Raverdy, V., Brage, S., Ridderstråle, M., Pedersen, Oluf Borbye, Hansen, Torben, Banasik, Karina, Rasmussen, Simon, Brunak, Søren & IMI-DIRECT consortium, I. C., 2023, In: Nature Biotechnology. 41, 3, p. 399–408 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  70. Published

    Discovery of novel heart rate-associated loci using the Exome Chip

    van den Berg, M. E., Warren, H. R., Cabrera, C. P., Verweij, N., Mifsud, B., Haessler, J., Bihlmeyer, N. A., Fu, Y-P., Weiss, S., Lin, H. J., Grarup, N., Li-Gao, R., Pistis, G., Shah, N., Brody, J. A., Müller-Nurasyid, M., Lin, H., Mei, H., Smith, A. V., Lyytikäinen, L-P. & 101 others, Hall, L. M., van Setten, J., Trompet, S., Prins, B. P., Isaacs, A., Radmanesh, F., Marten, J., Entwistle, A., Kors, J. A., Silva, C. T., Alonso, A., Bis, J. C., de Boer, R. A., de Haan, H. G., de Mutsert, R., Dedoussis, G., Dominiczak, A. F., Doney, A. S. F., Ellinor, P. T., Eppinga, R. N., Felix, S. B., Guo, X., Hagemeijer, Y., Hansen, Torben, Harris, T. B., Heckbert, S. R., Huang, P. L., Hwang, S., Kähönen, M., Kanters, Jørgen K., Kolcic, I., Launer, L. J., Li, M., Yao, X. J., Linneberg, Allan René, Liu, S., Macfarlane, P. W., Mangino, M., Morris, A. D., Mulas, A., Murray, A. D., Nelson, C. P., Orrù, M., Padmanabhan, S., Peters, A., Porteous, D. J., Poulter, N., Psaty, B. M., Qi, L., Raitakari, O. T., Rivadeneira, F., Roselli, C., Rudan, I., Sattar, N., Sever, P., Sinner, M. F., Soliman, E. Z., Spector, T. D., Stanton, A. V., Stirrups, K. E., Taylor, K. D., Tobin, M. D., Uitterlinden, A., Vaartjes, I., Hoes, A. W., van der Meer, P., Völker, U., Waldenberger, M., Xie, Z., Zoledziewska, M., Tinker, A., Polasek, O., Rosand, J., Jamshidi, Y., van Duijn, C. M., Zeggini, E., Jukema, J. W., Asselbergs, F. W., Samani, N. J., Lehtimäki, T., Gudnason, V., Wilson, J., Lubitz, S. A., Kääb, S., Sotoodehnia, N., Caulfield, M. J., Palmer, C. N. A., Sanna, S., Mook-Kanamori, D. O., Deloukas, P., Pedersen, Oluf Borbye, Rotter, J. I., Dörr, M., O'Donnell, C. J., Hayward, C., Arking, D. E., Kooperberg, C., van der Harst, P., Eijgelsheim, M., Stricker, B. H. C. & Munroe, P. B., 15 Jun 2017, In: Human Molecular Genetics. 26, 12, p. 2346-2363 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  71. Published

    Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals

    Surendran, P., Feofanova, E. V., Lahrouchi, N., Ntalla, I., Karthikeyan, S., Cook, J., Chen, L., Mifsud, B., Yao, C., Kraja, A. T., Cartwright, J. H., Hellwege, J. N., Giri, A., Tragante, V., Thorleifsson, G., Liu, D. J., Prins, B. P., Stewart, I. D., Cabrera, C. P., Eales, J. M. & 34 others, Akbarov, A., Auer, P. L., Bielak, L. F., Bis, J. C., Braithwaite, V. S., Brody, J. A., Daw, E. W., Warren, H. R., Drenos, F., Nielsen, S. F., Faul, J. D., Fauman, E. B., Fava, C., Varga, T. V., Zhao, J. H., Bork-Jensen, J., Grarup, Niels, Hansen, Torben, Have, C. T., Jørgensen, M. E., Karpe, F., Linneberg, Allan René, Pedersen, Oluf Borbye, Rasmussen, K. L., Sun, Y. V., Witte, D. R., Lind, L., Loos, Ruth, Nordestgaard, Børge, LifeLines Cohort Study, L. C. S., EPIC-CVD, E., EPIC-InterAct, E., Understanding Society Scientific Group, U. S. S. G. & Million Veteran Program, M. V. P., 2020, In: Nature Genetics. 52, 12, p. 1314-1332 19 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  72. Published

    Discovery of the GI Effects of GLP-1: An Historical Perspective

    Holst, Jens Juul, 2022, In: Digestive Diseases and Sciences. 67, p. 2716-2720

    Research output: Contribution to journal › Review › Research › peer-review

  73. Published

    Discovery of thymosin β4 as a human exerkine and growth factor

    Gonzalez-Franquesa, A., Stocks, Ben Nicholas, Borg, M. L., Kuefner, M., Kellezi, Emilie Dalbram, Nielsen, Thomas Svava, Agrawal, A., Pankratova, Stanislava, Chibalin, A. V., Karlsson, H. K. R., Gheibi, S., Björnholm, M., Jørgensen, Niklas Rye, Clemmensen, Christoffer, Treebak, Jonas Thue, Hostrup, Morten, Krook, A., Zierath, Juleen R & Deshmukh, Atul Shahaji, 2021, In: American Journal of Physiology: Cell Physiology. 321, 5, p. C770-C778 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  74. Published

    Discovery, characterization, and clinical development of the glucagon-like peptides

    Drucker, D. J., Habener, J. F. & Holst, Jens Juul, 1 Dec 2017, In: The Journal of Clinical Investigation. 127, 12, p. 4217-4227 11 p.

    Research output: Contribution to journal › Review › Research › peer-review

  75. Published

    Discrepancy between predicted and measured exercise intensity for eliciting the maximal rate of lipid oxidation

    Kittrell, H. D., DiMenna, F. J., Arad, A. D., Oh, W., Hofer, I., Walker, R. W., Loos, Ruth, Albu, J. B. & Nadkarni, G. N., 2023, In: Nutrition, Metabolism and Cardiovascular Diseases. 33, 11, p. 2189-2198

    Research output: Contribution to journal › Journal article › Research › peer-review

  76. Published

    Disease Progression and Pharmacological Intervention in a Nutrient-Deficient Rat Model of Nonalcoholic Steatohepatitis

    Tolbol, K. S., Stierstorfer, B., Rippmann, J. F., Veidal, S. S., Rigbolt, K. T. G., Schoenberger, T., Gillum, M. P., Hansen, H. H., Vrang, N., Jelsing, J., Feigh, M. & Broermann, A., May 2019, In: Digestive Diseases and Sciences. 64, 5, p. 1238-1256

    Research output: Contribution to journal › Journal article › Research › peer-review

  77. Published

    Disentangling the genetics of lean mass

    Karasik, D., Zillikens, M. C., Hsu, Y. H., Aghdassi, A., Akesson, K., Amin, N., Barroso, I., Bennett, D. A., Bertram, L., Bochud, M., Borecki, I. B., Broer, L., Buchman, A. S., Byberg, L., Campbell, H., Campos-Obando, N., Cauley, J. A., Cawthon, P. M., Chambers, J. C., Chen, Z. & 137 others, Cho, N. H., Choi, H. J., Chou, W. C., Cummings, S. R., de Groot, L. C. P. G. M., De Jager, P. L., Demuth, I., Diatchenko, L., Econs, M. J., Eiriksdottir, G., Enneman, A. W., Eriksson, J., Eriksson, J. G., Estrada, K., Evans, D. S., Feitosa, M. F., Fu, M., Gieger, C., Grallert, H., Gudnason, V., Lenore, L. J., Hayward, C., Hofman, A., Homuth, G., Huffman, K. M., Husted, L. B., Illig, T., Ingelsson, E., Ittermann, T., Jansson, J. O., Johnson, T., Biffar, R., Jordan, J. M., Jula, A., Karlsson, M., Khaw, K. T., Kilpeläinen, Tuomas O., Klopp, N., Kloth, J. S. L., Koller, D. L., Kooner, J. S., Kraus, W. E., Kritchevsky, S., Kutalik, Z., Kuulasmaa, T., Kuusisto, J., Laakso, M., Lahti, J., Lang, T., Langdahl, B. L., Lerch, M. M., Lewis, J. R., Lill, C., Lind, L., Lindgren, C., Liu, Y., Livshits, G., Ljunggren, Ö., Loos, Ruth, Lorentzon, M., Luan, J., Luben, R. N., Malkin, I., McGuigan, F. E., Medina-Gomez, C., Meitinger, T., Melhus, H., Mellström, D., Michaëlsson, K., Mitchell, B. D., Morris, A. P., Mosekilde, L., Nethander, M., Newman, A. B., O'Connell, J. R., Oostra, B. A., Orwoll, E. S., Palotie, A., Peacock, M., Perola, M., Peters, A., Prince, R. L., Psaty, B. M., Räikkönen, K., Ralston, S. H., Ripatti, S., Rivadeneira, F., Robbins, J. A., Rotter, J. I., Rudan, I., Salomaa, V., Satterfield, S., Schipf, S., Shin, C. S., Smith, A. V., Smith, S. B., Soranzo, N., Spector, T. D., Stancáková, A., Stefansson, K., Steinhagen-Thiessen, E., Stolk, L., Streeten, E. A., Styrkarsdottir, U., Swart, K. M. A., Thompson, P., Thomson, C. A., Thorleifsson, G., Thorsteinsdottir, U., Tikkanen, E., Tranah, G. J., Uitterlinden, A. G., van Duijn, C. M., van Schoor, N. M., Vandenput, L., Vollenweider, P., Völzke, H., Wactawski-Wende, J., Walker, M., J Wareham, N., Waterworth, D., Weedon, M. N., Wichmann, H. E., Widen, E., Williams, F. M. K., Wilson, J. F., Wright, N. C., Yerges-Armstrong, L. M., Yu, L., Zhang, W., Zhao, J. H., Zhou, Y., Nielson, C. M., Harris, T. B., Demissie, S., Kiel, D. P. & Ohlsson, C., 2019, In: American Journal of Clinical Nutrition. 109, 2, p. 276-287

    Research output: Contribution to journal › Journal article › Research › peer-review

  78. Published

    Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota

    Forslund, K., Hildebrand, F., Nielsen, T., Falony, G., Le Chatelier, E., Sunagawa, S., Prifti, E., Vieira-Silva, S., Gudmundsdottir, V., Pedersen, H. K., Arumugam, M., Kristiansen, K., Yvonne Voigt, A., Vestergaard, H., Hercog, R., Igor Costea, P., Roat Kultima, J., Li, J., Jørgensen, T., Levenez, F. & 9 others, Dore, J., Nielsen, H. B., Brunak, Søren, Raes, J., Hansen, Torben, Wang, J., Dusko Ehrlich, S., Bork, P. & Pedersen, Oluf Borbye, 2015, In: Nature. 528, 7581, p. 262-266 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  79. Published

    Displaying the researched body: Growing cell portraits in a medical museum

    Whiteley, Louise, Tybjerg, Karin & Pedersen, B. V., 1 Feb 2017, In: Leonardo & Leonardo Music Journal. 50, 1, p. 86-87 2 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  80. Published

    Disrupted circadian oscillations in type 2 diabetes are linked to altered rhythmic mitochondrial metabolism in skeletal muscle

    Gabriel, B. M., Altıntaş, Ali, Smith, J. A. B., Sardon-Puig, L., Zhang, X., Basse, A. L., Laker, R. C., Gao, H., Liu, Z., Dollet, L., Treebak, Jonas Thue, Zorzano, A., Huo, Z., Rydén, M., Lanner, J. T., Esser, K. A., Barrès, Romain, Pillon, N. J., Krook, A. & Zierath, Juleen R, 2021, In: Science Advances. 7, 43, 20 p., eabi9654.

    Research output: Contribution to journal › Journal article › Research › peer-review

  81. Published

    Disruption of GPR35 Signaling in Bone Marrow-Derived Cells Does Not Influence Vascular Inflammation and Atherosclerosis in Hyperlipidemic Mice

    Baumgartner, R., Casagrande, F. B., Mikkelsen, R. B., Berg, M., Polyzos, K. A., Forteza, M. J., Arora, A., Schwartz, Thue W., Hjorth, Siv Annegrethe & Ketelhuth, D. F. J., 2021, In: Metabolites. 11, 7, 10 p., 411.

    Research output: Contribution to journal › Journal article › Research › peer-review

  82. Published

    Disruption of glucagon receptor signaling causes hyperaminoacidemia exposing a possible liver-alpha-cell axis

    Galsgaard, Katrine Douglas, Winther-Sørensen, Marie, Ørskov, Cathrine, Kissow, Hannelouise, Poulsen, Steen Seier, Vilstrup, H., Prehn, C., Adamski, J., Jepsen, Sara Lind, Hartmann, Bolette, Dal, Jenna Elizabeth Hunt, Charron, M. J., Pedersen, Jens, Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, 2018, In: American Journal of Physiology: Endocrinology and Metabolism. 314, 1, p. E93-E103

    Research output: Contribution to journal › Journal article › Research › peer-review

  83. Published

    Disruption of the GH Receptor Gene in Adult Mice Increases Maximal Lifespan in Females

    Junnila, R. K., Duran-Ortiz, S., Suer, O., Sustarsic, E. G., Berryman, D. E., List, E. O. & Kopchick, J. J., Dec 2016, In: Endocrinology. 157, 12, p. 4502-4513

    Research output: Contribution to journal › Journal article › Research › peer-review

  84. Published

    Dissecting adipose tissue lipolysis: molecular regulation and implications for metabolic disease

    Nielsen, Thomas Svava, Jessen, N., Jørgensen, J. O. L., Møller, N. & Lund, S., Jun 2014, In: Journal of Molecular Endocrinology. 52, 3, p. R199-R222 24 p.

    Research output: Contribution to journal › Review › Research › peer-review

  85. Published

    Dissecting signaling and functions of adhesion G protein-coupled receptors

    Araç, D., Aust, G., Calebiro, D., Engel, F. B., Formstone, C., Goffinet, A., Hamann, J., Kittel, R. J., Liebscher, I., Lin, H-H., Monk, K. R., Petrenko, A., Piao, X., Prömel, S., Schiöth, H. B., Schwartz, T. W., Stacey, M., Ushkaryov, Y. A., Wobus, M., Wolfrum, U. & 2 others, Xu, L. & Langenhan, T., Dec 2012, In: Annals of the New York Academy of Sciences. 1276, p. 1-25 25 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  86. Published

    Dissociated incretin hormone response to protein versus fat ingestion in obese subjects

    Lindgren, O., Carr, R., Holst, Jens Juul, Deacon, Carolyn F. & Ahren, B., Jul 2011, In: Diabetes, Obesity and Metabolism Online. 13, 9, p. 863-865 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  87. Published

    Distal gastrectomy in pancreaticoduodenectomy is associated with accelerated gastric emptying, enhanced postprandial release of GLP-1, and improved insulin sensitivity

    Harmuth, S., Wewalka, M., Holst, Jens Juul, Nemecek, R., Thalhammer, S., Schmid, R., Sahora, K., Gnant, M. & Miholić, J., Jan 2014, In: Journal of Gastrointestinal Surgery. 18, 1, p. 52-9 8 p.

    Research output: Contribution to journal › Conference article › Research › peer-review

  88. Published

    Distal, not proximal, colonic acetate infusions promote fat oxidation and improve metabolic markers in overweight/obese men

    van der Beek, C. M., Canfora, E. E., Lenaerts, K., Troost, F. J., Damink, S. W. M. O., Holst, Jens Juul, Masclee, A. A. M., Dejong, C. H. C. & Blaak, E. E., 11 Oct 2016, In: Clinical Science. 130, 22, p. 2073-2082 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  89. Published

    Distilling causality between physical activity traits and obesity via Mendelian randomization

    Wang, Z., Davey Smith, G., Loos, Ruth & den Hoed, M., 2023, In: Communications Medicine. 3, 6 p., 173.

    Research output: Contribution to journal › Journal article › Research › peer-review

  90. Published

    Distinct alterations of gut morphology and microbiota characterize accelerated diabetes onset in nonobese diabetic mice

    Simon, M., Reinbeck, A. L., Wessel, C., Heindirk, J., Jelenik, T., Kaul, K., Arreguin-Cano, J., Strom, A., Blaut, M., Backhed, F., Burkart, V. & Roden, M., 2020, In: Journal of Biological Chemistry. 295, 4, p. 969-980 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  91. Published

    Distinct differences in gut microbial composition and functional potential from lean to morbidly obese subjects

    Meijnikman, A. S., Aydin, O., Prodan, A., Tremaroli, V., Herrema, H., Levin, E., Acherman, Y., Bruin, S., Gerdes, V. E., Backhed, F., Groen, A. K. & Nieuwdorp, M., 2020, In: Journal of Internal Medicine. 288, 6, p. 699-710

    Research output: Contribution to journal › Journal article › Research › peer-review

  92. Published

    Distinct life histories impact dikaryotic genome evolution in the rust fungus Puccinia striiformis causing stripe rust in wheat

    Chen, Yan-Jun, Schwessinger, B., Tien, R., Vogt, J. K., Sperschneider, J., Nagar, R., McMullan, M., Sicheritz-Pontén, Thomas, Sørensen, C. K., Hovmøller, M. S., Rathjen, J. P. & Justesen, A. F., 2020, In: Genome Biology and Evolution. 12, 5, p. 597-617

    Research output: Contribution to journal › Journal article › Research › peer-review

  93. Published

    Distinct signalling properties of insulin receptor substrate (IRS)-1 and IRS-2 in mediating insulin/IGF-1 action

    Rabiee, A., Krüger, M., Ardenkjær-Larsen, J., Ronald Kahn, C. & Emanuelli, Brice, 2018, In: Cellular Signalling. 47, p. 1-15

    Research output: Contribution to journal › Journal article › Research › peer-review

  94. Published

    Distribution and characterization of different molecular products of Pro-somatostatin in the hypothalmus and posterior pituitary lobe of the mongolian gerbil (Meriones unguiculatus)

    Larsen, P. J., Bersani, M., Holst, Jens Juul, Møller, M. & Mikkelsen, J. D., 1992, In: Journal of Neuroscience. 12, hæfte 3, p. 946-961

    Research output: Contribution to journal › Journal article › Research › peer-review

  95. Published

    Disturbed eating behaviours do not impact treatment response in a paediatric obesity chronic care treatment programme

    Fogh, M., Lund, Morten Asp Vonsild, Mollerup, P. M., Johansen, M. O., Melskens, R. H., Trier, C., Kloppenborg, J. T., Hansen, Torben & Holm, Jens-Christian, 2020, In: Journal of Paediatrics and Child Health. 56, 4, p. 542-549 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  96. Published

    Disturbed postprandial glucose metabolism and gut hormone responses in non-diabetic patients with psoriasis

    Gyldenløve, M., Vilsbøll, Tina, Holst, Jens Juul, Zachariae, Claus, Skov, L. & Knop, Filip Krag, Nov 2016, In: British Journal of Dermatology. 175, 5, p. 1085–1088

    Research output: Contribution to journal › Letter › Research › peer-review

  97. Published

    Divalent metal transporter 1 regulates iron-mediated ROS and pancreatic ß cell fate in response to cytokines

    Hansen, J. B., Tonnesen, M. F., Madsen, A. N., Hagedorn, P., Friberg, J., Grunnet, L. G., Heller, R. S., Nielsen, A. Ø., Størling, J., Baeyens, L., Anker-Kitai, L., Qvortrup, K., Bouwens, L., Efrat, S., Aalund, M., Andrews, N. C., Billestrup, N., Karlsen, A. E., Holst, B., Pociot, F. & 1 others, Mandrup-Poulsen, Thomas, 2012, In: Cell Metabolism. 16, 4, p. 449-61 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  98. Published

    Divergent Roles of α5 and β4 Nicotinic Receptor Subunits in Food Reward and Nicotine-induced Weight Loss in Male Mice

    Breum, Alberte Wollesen, Falk, S., Svendsen, C. S. A., Nicolaisen, T. S., Mathiesen, C. V., Maskos, U. & Clemmensen, Christoffer, 2022, In: Endocrinology. 163, 7, 9 p., bqac079.

    Research output: Contribution to journal › Journal article › Research › peer-review

  99. Published

    Divergent effects of resistance and endurance exercise on plasma bile acids, FGF19, and FGF21 in humans

    Morville, T., Sahl, Ronni Eg, Trammell, Sam, Svenningsen, J. S., Gillum, M. P., Helge, Jørn Wulff & Clemmensen, Christoffer, 2018, In: JCI Insight. 3, 15, p. 1-13 e122737.

    Research output: Contribution to journal › Journal article › Research › peer-review

  100. Published

    Diverse repertoire of human adipocyte subtypes develops from transcriptionally distinct mesenchymal progenitor cells

    Min, S. Y., Desai, A., Yang, Z., Sharma, A., DeSouza, T., Genga, R. M. J., Kucukural, A., Lifshitz, L. M., Nielsen, S., Schéele, Camilla Charlotte Nielsen, Maehr, R., Garber, M. & Corvera, S., 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 36, p. 17970-17979

    Research output: Contribution to journal › Journal article › Research › peer-review

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