Novo Nordisk Foundation Center for Basic Metabolic Research

  1. Published

    The gut microbiota engages different signaling pathways to induce Duox2 expression in the ileum and colon epithelium

    Sommer, F. & Bäckhed, G. F., Mar 2015, In: Mucosal Immunology. 8, 2, p. 372-9 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    The gut microbiota in multiple sclerosis varies with disease activity

    Thirion, F., Sellebjerg, Finn Thorup, Fan, Yong, Lyu, Liwei, Hansen, T. H., Pons, N., Levenez, F., Quinquis, B., Stankevic, Evelina, Søndergaard, H. B., Dantoft, T. M., Poulsen, C. S., Forslund, S. K., drb459, drb459, Hansen, Torben, Brix, S., Oturai, A., Sørensen, Per Soelberg, Ehrlich, S. D. & Pedersen, Oluf Borbye, 2023, In: Genome Medicine. 15, 17 p., 1.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    The gut microbiota in type 2 diabetes

    Nielsen, T., Allin, K. H. & Pedersen, Oluf Borbye, 1 Jan 2016, The Genetics of Type 2 Diabetes and Related Traits: Biology, Physiology and Translation. Springer, p. 275-293 19 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  4. Published

    The gut microbiota modulates host amino acid and glutathione metabolism in mice

    Mardinoglu, A., Shoaie, S., Bergentall, M., Ghaffari, P., Zhang, C., Larsson, E., Bäckhed, G. F. & Nielsen, J., 2015, In: Molecular Systems Biology. 11, 10, p. 1-15 15 p., 834.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    The gut microbiota regulates hypothalamic inflammation and leptin sensitivity in Western diet-fed mice via a GLP-1R-dependent mechanism

    Heiss, C. N., Mannerås-Holm, L., Lee, Y. S., Serrano-Lobo, J., Håkansson Gladh, A., Seeley, R. J., Drucker, D. J., Bäckhed, F. & Olofsson, L. E., 2021, In: Cell Reports. 35, 8, 16 p., 109163.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    The human PINK1 locus is regulated in vivo by a non-coding natural antisense RNA during modulation of mitochondrial function

    Schéele, Camilla Charlotte Nielsen, Petrovic, N., Faghihi, M. A., Lassmann, T., Fredriksson, K., Rooyackers, O., Wahlestedt, C., Good, L. & Timmons, J. A., 15 Mar 2007, In: BMC Genomics. 8, p. 74

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    The human batokine EPDR1 regulates β-cell metabolism and function

    Cataldo Bascunan, Luis Rodrigo, Gao, Q., Argemi Muntadas, Lidia, Hodek, O., Cowan, E., Hladkou, S., Gheibi, S., Spegel, P., Prasad, R. B., Eliasson, L., Schéele, Camilla Charlotte Nielsen, Fex, M., Mulder, H. & Moritz, Thomas, 2022, In: Molecular Metabolism. 66, 14 p., 101629.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    The human herpes virus 8-encoded chemokine receptor is required for angioproliferation in a murine model of Kaposi's sarcoma.

    Jensen, K., Manfra, D., Grisotto, M., Martin, A., Vassileva, G., Kelley, K., Schwartz, Thue W. & Lira, S., Mar 2005, In: Journal of immunology (Baltimore, Md. : 1950).

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    The human small intestinal microbiota is driven by rapid uptake and conversion of simple carbohydrates

    Zoetendal, E. G., Raes, J., van den Bogert, B., Arumugam, Mani, Booijink, C. C. G. M., Troost, F. J., Bork, P., Wels, M., de Vos, W. M. & Kleerebezem, M., 2012, In: I S M E Journal. 6, 7, p. 1415-26 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    The identification and functional annotation of RNA structures conserved in vertebrates

    Seemann, Ernst Stefan, Mirza, A. H., Hansen, C., Bang-Berthelsen, C. H., Garde, C., Christensen-Dalsgaard, M., Torarinsson, E., Yao, Z., Workman, C. T., Pociot, Flemming, Nielsen, Henrik, Tommerup, Niels, Ruzzo, W. L. & Gorodkin, Jan, 2017, In: Genome Research. 27, p. 1371-1383 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    The immunoproteasome is induced by cytokines and regulates apoptosis in human islets

    Lundh, M., Bugliani, M., Dahlby, T., Chou, D. H., Wagner , B., Ghiasi, S. M., De Tata, V., Chen, Z., Lund, Marianne N., Davies, Michael J., Marchetti, P. & Mandrup-Poulsen, Thomas, 2017, In: Journal of Endocrinology. 233, 3, p. 369-379 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    The impact of EndoBarrier gastrointestinal liner in obese patients with normal glucose tolerance and in patients with type 2 diabetes

    Rohde, U., Federspiel, C. A., Vilmann, Peter, Langholz, Ebbe, Friis, S. U., Krakauer, M., Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, Feb 2017, In: Diabetes, Obesity and Metabolism. 19, 2, p. 189-199 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    The impact of acute fluctuations in plasma glucose on echocardiographic derived measures of systolic function in patients with type 1 diabetes

    Andreasen, C. R., Andersen, A., Haqelqvist, P. G., Abelin, K., Lauritsen, J. V., Jorgensen, P. G., Engberg, S., Faber, Jens, Holst, Jens Juul, Pedersen-Bjergaard, Ulrik, Knop, Filip Krag & Vilsbøll, Tina, 2021, In: Diabetologia. 64, SUPPL 1, p. 135-136 2 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  14. Published

    The impact of acute glycaemic fluctuations on left ventricular systolic function in insulin-treated type 2 diabetes

    Andersen, A., Jorgensen, P. G., Bagger, J. I., Baldassarre, M. P. A., Christensen, M., Abelin, K. U., Faber, Jens, Pedersen-Bjergaard, Ulrik, Holst, Jens Juul, Lindhardt, T., Gislason, Gunnar Hilmar, Knop, Filip Krag & Vilsbøll, Tina, 2020, In: Diabetologia. 63, SUPPL 1, p. S429-S429 897.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  15. Published

    The impact of anorexia nervosa and BMI polygenic risk on childhood growth: A 20-year longitudinal population-based study

    Abdulkadir, M., Hübel, C., Herle, M., Loos, Ruth, Breen, G., Bulik, C. M. & Micali, N., 2022, In: American Journal of Human Genetics. 109, 7, p. 1242-1254 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    The impact of dipeptidyl peptidase 4 inhibition on incretin effect, glucose tolerance, and gastrointestinal-mediated glucose disposal in healthy subjects

    Rhee, N. A., Østoft, S. H., Holst, Jens Juul, Deacon, Carolyn F., Vilsbøll, T. & Knop, Filip Krag, 16 Jun 2014, In: European Journal of Endocrinology. 171, 3, p. 353-362 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    The impact of short chain fatty acids on GLP-1 and PYY secretion from the isolated perfused rat colon

    Christiansen, Charlotte Bayer, Gabe, M. B. N., Svendsen, B., Dragsted, Lars Ove, Rosenkilde, Mette & Holst, Jens Juul, 2018, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 315, 1, p. G53-G65 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    The impact of surgery and oncological treatment on risk of type 2 diabetes onset in patients with colorectal cancer: nationwide cohort study in Denmark

    Krag, C., Svane, M. S., Madsbad, Sten, Graversen, S. B., Christensen, J. F., Sørensen, Thorkild I.A., Lehrskov, L. L. & Laurberg, T., 2024, In: eLife. 12, 13 p., RP89354.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    The importance of endogenously secreted GLP-1 and GIP for postprandial glucose tolerance and β-cell function after Roux-en-Y gastric bypass and sleeve gastrectomy surgery

    Hindsø, M., Hedbäck, N., Svane, M. S., Møller, A., Martinussen, C., Jørgensen, N. B., Dirksen, C., Gasbjerg, Lærke Smidt, Kristiansen, V. B., Hartmann, Bolette, Rosenkilde, Mette, Holst, Jens Juul, Madsbad, Sten & Bojsen-Møller, K. N., 2023, In: Diabetes. 72, 3, p. 336–347

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    The importance of glucose-dependent insulinotropic polypeptide receptor activation for the effects of tirzepatide

    Gasbjerg, Lærke Smidt, Rosenkilde, Mette, Meier, J. J., Holst, Jens Juul & Knop, Filip Krag, 2023, In: Diabetes, Obesity and Metabolism. 25, 11, p. 3079-3092

    Research output: Contribution to journalReviewResearchpeer-review

  21. Published

    The incretin effect does not differ in trained and untrained, young, healthy men

    Lund, M. T., Dalby, S., Hartmann, Bolette, Helge, Jørn Wulff, Holst, Jens Juul & Dela, Flemming, Mar 2014, In: Acta Physiologica. 210, 3, p. 565-72 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    The incretin effect in patients with maturity onset diabetes of the young

    Ostoft, S. H., Bagger, J. I., Hansen, T., Pedersen, O., Holst, Jens Juul, Knop, Filip Krag & Vilsboll, T., 2012, In: Diabetologia. 55, p. S144-S144

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    The incretin system in healthy humans: The role of GIP and GLP-1

    Holst, Jens Juul, 2019, In: Metabolism. 96, p. 46-55

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    The incretin/glucagon system as a target for pharmacotherapy of obesity

    Del Prato, S., Gallwitz, B., Holst, Jens Juul & Meier, J. J., 2022, In: Obesity Reviews. 23, 2, 13 p., e13372.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    The independent effect of type 2 diabetes mellitus on ischemic heart disease, stroke, and death: a population-based study of 13,000 men and women with 20 years of follow-up

    Almdal, Thomas Peter, Scharling, H., Jensen, J. S. & drb459, drb459, 12 Jul 2004, In: J A M A Internal Medicine. 164, 13, p. 1422-6 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review