Novo Nordisk Foundation Center for Basic Metabolic Research

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  1. Published

    White adipose remodeling during browning in mice involves YBX1 to drive thermogenic commitment

    Rabiee, A., Plucinska, Kaja, Isidor, Marie Sophie, Brown, E. L., Tozzi, M., Sidoli, S., Petersen, P. S. S., Agueda Oyarzabal, Marina, Torsetnes, S. B., Chehabi, G. N., Lundh, M., Altıntaş, Ali, Barrès, Romain, Jensen, O. N., Gerhart-Hines, Zach & Emanuelli, Brice, 2021, In: Molecular Metabolism. 44, 17 p., 101137.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Whole blood co-expression modules associate with metabolic traits and type 2 diabetes: an IMI-DIRECT study

    Gudmundsdottir, V., Pedersen, H. K., Mazzoni, G., Allin, K. H., Artati, A., Beulens, J. W., Banasik, K., Brorsson, C., Cederberg, H., Chabanova, E., De Masi, F., Elders, P. J., Forgie, I., Giordano, G. N., Grallert, H., Gupta, R., Haid, M., Hansen, T., Hansen, T. H., Hattersley, A. T. & 36 others, Heggie, A., Hong, M., Jones, A. G., Koivula, R., Kokkola, T., Laakso, M., Løngreen, P., Mahajan, A., Mari, A., McDonald, T. J., McEvoy, D., Musholt, P. B., Pavo, I., Prehn, C., Ruetten, H., Ridderstrale, M., Rutters, F., Sharma, S., Slieker, R. C., Syed, A., Tajes, J. F., Thomas, Cecilia Engel, Thomsen, Henrik S., Vangipurapu, J., Vestergaard, H., Vinuela, A., Wesolowska-Andersen, A., Walker, M., Adamski, J., Schwenk, J. M., McCarthy, M., Pearson, E., Dermitzakis, E., Franks, P. W., Pedersen, Oluf Borbye & Brunak, Søren, 2020, In: Genome Medicine. 12, 1, 17 p., 109.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Whole exome sequencing identified a novel splice donor site variant in interleukin 2 receptor alpha chain

    Waheed, N., Naseer, M., Haider, N., Suleman, Sufyan & Ullah, A., 2023, In: Immunogenetics. 75, p. 71-79

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Whole exome sequencing identifies frequent somatic mutations in cell-cell adhesion genes in chinese patients with lung squamous cell carcinoma

    Li, C., Gao, Z., Li, F., Li, X., Sun, Y., Wang, M., Li, D., Wang, R., Li, F., Fang, R., Pan, Y., Luo, X., He, J., Zheng, L., Xia, J., Qiu, L., He, J., Ye, T., Zhang, R., He, M. & 32 others, Zhu, M., Hu, H., Shi, T., Zhou, X., Sun, M., Tian, S., Zhou, Y., Wang, Q., Chen, L., Yin, G., Lu, J., Wu, R., Guo, G., Li, Y., Hu, X., Li, L., Asan, Wang, Q., Yin, Y., Feng, Q., Wang, B., Wang, H., Wang, M., Yang, X., Zhang, X., Yang, H., Jin, L., Wang, C., Ji, H., Chen, H., Wang, J. & Wei, Q., 2015, In: Scientific Reports. 5, 11 p., 14237 .

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Whole exome sequencing of insulinoma reveals recurrent T372R mutations in YY1

    Cao, Y., Gao, Z., Li, L., Jiang, X., Shan, A., Cai, J., Peng, Y., Li, Y., Jiang, X., Huang, X., Wang, J., Wei, Q., Qin, G., Zhao, J., Jin, X., Liu, L., Li, Y., Wang, W., Wang, J. & Ning, G., 2013, In: Nature Communications. 4, 6 p., 2810.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Whole genome sequence analysis of blood lipid levels in >66,000 individuals

    Selvaraj, M. S., Li, X., Li, Z., Pampana, A., Zhang, D. Y., Park, J., Aslibekyan, S., Bis, J. C., Brody, J. A., Cade, B. E., Chuang, L. M., Chung, R. H., Curran, J. E., de las Fuentes, L., de Vries, P. S., Duggirala, R., Freedman, B. I., Graff, M., Guo, X., Heard-Costa, N. & 27 others, Hidalgo, B., Hwu, C. M., Irvin, M. R., Kelly, T. N., Kral, B. G., Lange, L., Li, X., Lisa, M., Lubitz, S. A., Manichaikul, A. W., Michael, P., Montasser, M. E., Morrison, A. C., Naseri, T., O’Connell, J. R., Palmer, N. D., Peyser, P. A., Reupena, M. S., Smith, J. A., Sun, X., Taylor, K. D., Tracy, R. P., Tsai, M. Y., Wang, Z., Wang, Y., Loos, Ruth & NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, N. T. F. P. M. (. C., 2022, In: Nature Communications. 13, 18 p., 5995.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Whole genome sequencing identifies structural variants contributing to hematologic traits in the NHLBI TOPMed program

    Wheeler, M. M., Stilp, A. M., Rao, S., Halldórsson, B. V., Beyter, D., Wen, J., Mihkaylova, A. V., McHugh, C. P., Lane, J., Jiang, M. Z., Raffield, L. M., Jun, G., Sedlazeck, F. J., Metcalf, G., Yao, Y., Bis, J. B., Chami, N., de Vries, P. S., Desai, P., Floyd, J. S. & 39 others, Gao, Y., Kammers, K., Kim, W., Moon, J. Y., Ratan, A., Yanek, L. R., Almasy, L., Becker, L. C., Blangero, J., Cho, M. H., Curran, J. E., Fornage, M., Kaplan, R. C., Lewis, J. P., Loos, Ruth, Mitchell, B. D., Morrison, A. C., Preuss, M., Psaty, B. M., Rich, S. S., Rotter, J. I., Tang, H., Tracy, R. P., Boerwinkle, E., Abecasis, G. R., Blackwell, T. W., Smith, A. V., Johnson, A. D., Mathias, R. A., Nickerson, D. A., Conomos, M. P., Li, Y., Þorsteinsdóttir, U., Magnússon, M. K., Stefansson, K., Pankratz, N. D., Bauer, D. E., Auer, P. L. & Reiner, A. P., 2022, In: Nature Communications. 13, 18 p., 7592.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Whole grain-rich diet reduces body weight and systemic low-grade inflammation without inducing major changes of the gut microbiome: a randomised cross-over trial

    Roager, H. M., Vogt, J. K., Kristensen, M. B., Hansen, L. B. S., Ibrügger, S., Mærkedahl, R. B., Bahl, M. I., Lind, M. V., Nielsen, R. L., Frøkiær, H., Gøbel, R. J., Landberg, R., Ross, A. B., Brix, S., Holck, J., Meyer, A. S., Sparholt, M. H., Christensen, A. F., Carvalho, V., Hartmann, B. & 18 others, Holst, Jens Juul, Rumessen, J. J., Linneberg, Allan René, Sicheritz-Pontén, T., Dalgaard, M. D., Blennow, Andreas, Frandsen, H. L., Villas-Bôas, S., Kristiansen, Karsten, drb459, drb459, Hansen, Torben, Ekstrøm, Claus Thorn, Ritz, C., Nielsen, H. B., Pedersen, Oluf Borbye, Gupta, R., Lauritzen, Lotte & Licht, T. R., Jan 2019, In: Gut. 68, 1, p. 83-93 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Whole-exome sequencing identifies a polymorphism in the BMP5 gene associated with SSRI treatment response in major depression

    Tammiste, A., Jiang, T., Fischer, K., Mägi, R., Krjutskov, K., Pettai, K., Esko, T., Li, Y., Tansey, K. E., Carroll, L. S., Uher, R., McGuffin, P., Vosa, U., Tsernikova, N., Saria, A., Ng, P. C., Eller, T., Vasar, V., Nutt, D. J., Maron, E. & 2 others, Wang, J. & Metspalu, A., 2013, In: Journal of Psychopharmacology. 27, 10, p. 915-920 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Whole-exome sequencing of 2,000 Danish individuals and the role of rare coding variants in type 2 diabetes

    Lohmueller, K. E., Sparsø, T. H., Li, Q., Galijatovic, E. A. A., Korneliussen, T. S., Albrechtsen, A., Banasik, K., Grarup, N., Hallgrimsdottir, I., Kiil, K., Oskari Kilpeläinen, T., Krarup, N. T., Pers, T. H., Sanchez, G., Hu, Y., DeGiorgio, M., Jørgensen, T., Sandbæk, A., Lauritzen, T., Brunak, S. & 6 others, Kristiansen, Karsten, Li, Y., Hansen, Torben, Wang, J., Nielsen, Rasmus & Pedersen, Oluf Borbye, 5 Dec 2013, In: American Journal of Human Genetics. 93, 6, p. 1072-1086 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Whole-genome and Transcriptome Sequencing of Prostate Cancer Identify New Genetic Alterations Driving Disease Progression

    Ren, S., Wei, G-H., Liu, D., Wang, L., Hou, Y., Zhu, S., Peng, L., Zhang, Q., Cheng, Y., Su, H., Zhou, X., Zhang, J., Li, F., Zheng, H., Zhao, Z., Yin, C., He, Z., Gao, X., Zhau, H. E., Chu, C-Y. & 42 others, Wu, J. B., Collins, C., Volik, S. V., Bell, R., Huang, J., Wu, K., Xu, D., Ye, D., Yu, Y., Zhu, L., Qiao, M., Lee, H., Yang, Y., Zhu, Y., Shi, X., Chen, R., Wang, Y., Xu, W., Cheng, Y., Xu, C., Gao, X., Zhou, T., Yang, B., Hou, J., Liu, L., Zhang, Z., Zhu, Y., Qin, C., Shao, P., Pang, J., Chung, L. W. K., Xu, J., Wu, C., Zhong, W., Xu, X., Li, Y., Zhang, X., Wang, J., Yang, H., Wang, J., Huang, H. & Sun, Y., 2018, In: European Urology. 73, 3, p. 322-339 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Whole-genome and whole-exome sequencing of bladder cancer identifies frequent alterations in genes involved in sister chromatid cohesion and segregation

    Guo, G., Sun, X., Chen, C., Wu, S., Huang, P., Li, Z., Dean, M., Huang, Y., Jia, W., Zhou, Q., Tang, A., Yang, Z., Li, X., Song, P., Zhao, X., Ye, R., Zhang, S., Lin, Z., Qi, M., Wan, S. & 36 others, Xie, L., Fan, F., Nickerson, M. L., Zou, X., Hu, X., Xing, L., Lv, Z., Mei, H., Gao, S., Liang, C., Gao, Z., Lu, J., Yu, Y., Liu, C., Li, L., Fang, X., Jiang, Z., Yang, J., Li, C., Zhao, X., Chen, J., Zhang, F., Lai, Y., Lin, Z., Zhou, F., Chen, H., Chan, H. C., Tsang, S., Theodorescu, D., Li, Y., Zhang, X., Wang, J., Yang, H., Gui, Y., Wang, J. & Cai, Z., 2013, In: Nature Genetics. 45, 12, p. 1459-1463 5 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  13. Published

    Whole-genome bisulfite sequencing of multiple individuals reveals complementary roles of promoter and gene body methylation in transcriptional regulation

    Lou, S., Lee, H., Qin, H., Li, J., Gao, Z., Liu, X., Chan, L. L., Lam, V. K. L., So, W., Wang, Y., Lok, S., Wang, J., Ma, R. C. W., Tsui, S. K., Chan, J. C. N., Chan, T. & Yip, K. Y., 2014, In: Genome Biology (Online Edition). 15, 7, 21 p., 408.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Whole-genome sequence variation, population structure and demographic history of the Dutch population

    Francioli, L. C., Menelaou, A., Pulit, S. L., Van Dijk, F., Palamara, P. F., Elbers, C. C., Neerincx, P. B. T., Ye, K., Guryev, V., Kloosterman, W. P., Deelen, P., Abdellaoui, A., Van Leeuwen, E. M., Van Oven, M., Vermaat, M., Li, M., Laros, J. F. J., Karssen, L. C., Kanterakis, A., Amin, N. & 64 others, Hottenga, J. J., Lameijer, E., Kattenberg, M., Dijkstra, M., Byelas, H., Van Settenl, J., Van Schaik, B. D. C., Bot, J., Nijman, I. J., Renkens, I., Marscha, T., Schonhuth, A., Hehir-Kwa, J. Y., Handsaker, R. E., Polak, P., Sohail, M., Vuzman, D., Hormozdiari, F., Van Enckevort, D., Mei, H., Koval, V., Moed, M. H., Van der Velde, K. J., Rivadeneira, F., Estrada, K., Medina-Gomez, C., Isaacs, A., McCarroll, S. A., Beekrnan, M., De Craen, A. J. M., Suchiman, H. E. D., Hofman, A., Oostra, B., Uitterlinden, A. G., Willemsen, G., Plattee, M., Veldink, J. H., Van den Berg, L. H., Pitts, S. J., Potluri, S., Sundar, P., Cox, D. R., Sunyaev, S. R., Den Dunnen, J. T., Stoneking, M., De Knijff, P., Kayser, M., Li, Q., Li, Y., Du, Y., Chen, R., Cao, H., Li, N., Cao, S., Wang, J., Bovenberg, J. A., Peer, I., Slagboom, P. E., Van Duijn, C. M., Boomsma, D. I., Van Ommen, G. B., De Bakker, P. I. W., Swertz, M. A. & Wijmenga, C., 2014, In: Nature Genetics. 46, 8, p. 818-825 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Whole-genome sequences of DA and F344 rats with different susceptibilities to arthritis, autoimmunity, inflammation and cancer

    Guo, X., Brenner, M., Zhang, X., Laragione, T., Tai, S., Li, Y., Bu, J., Yin, Y., Shah, A. A., Kwan, K., Li, Y., Wang, J. & Gulko, P. S., 2013, In: Genetics. 194, 4, p. 1017-1028 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Whole-genome sequencing identifies recurrent mutations in hepatocellular carcinoma

    Kan, Z., Zheng, H., Liu, X., Li, S., Barber, T. D., Gong, Z., Gao, H., Hao, K., Willard, M. D., Xu, J., Hauptschein, R., Rejto, P. A., Fernandez, J., Wang, G., Zhang, Q., Wang, B., Chen, R., Wang, J., Lee, N. P., Zhou, W. & 30 others, Lin, Z., Peng, Z., Yi, K., Chen, S., Li, L., Fan, X., Yang, J., Ye, R., Ju, J., Wang, K., Estrella, H., Deng, S., Wei, P., Qiu, M., Wulur, I. H., Liu, J., Ehsani, M. E., Zhang, C., Loboda, A., Sung, W. K., Aggarwal, A., Poon, R. T., Fan, S. T., Wang, J., Hardwick, J., Reinhard, C., Dai, H., Li, Y., Luk, J. M. & Mao, M., 2013, In: Genome Research. 23, p. 1422-1433 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Whole-genome sequencing reveals untapped genetic potential in Africa's indigenous cereal crop sorghum

    Mace, E. S., Tai, S., Gilding, E. K., Li, Y., Prentis, P. J., Bian, L., Campbell, B. C., Hu, W., Innes, D. J., Han, X., Cruickshank, A., Dai, C., Frere, C., Zhang, H., Hunt, C. H., Wang, X., Shatte, T., Wang, M., Su, Z., Li, J. & 4 others, Lin, X., Godwin, I. D., Jordan, D. R. & Wang, J., 2013, In: Nature Communications. 4, 9 p., 2320.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Why Warburg Works: Lactate Controls Immune Evasion through GPR81

    Jørgensen, Kathrine Lundø, Trauelsen, Mette, Pedersen, Stine Helene Falsig & Schwartz, Thue W., 2020, In: Cell Metabolism. 31, 4, p. 666–668 3 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  19. Published

    Why is it so difficult to measure glucagon-like peptide-1 in a mouse?

    Windeløv, Johanne Agerlin, Albrechtsen, Nicolai Jacob Wewer, Kuhre, Rune Ehrenreich, Jepsen, Sara Lind, Hornburg, D., Pedersen, Jens, Jensen, E. P., Galsgaard, Katrine Douglas, Winther-Sørensen, Marie, Ørgaard, A., Deacon, Carolyn F., Mann, Matthias, Kissow, Hannelouise, Hartmann, Bolette & Holst, Jens Juul, Oct 2017, In: Diabetologia. 60, 10, p. 2066-2075 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Why looking at things matter: An argument from the aesthethic philosophy of Alexander Gottlieb Baumgarten

    Bencard, Adam, 2018, In: Museums Worlds: Advances in Research. 6, 1, p. 48-59 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Will the COVID-19 pandemic worsen the obesity epidemic?

    Clemmensen, Christoffer, Petersen, M. B. & Sørensen, Thorkild I.A., 2020, In: Nature Reviews Endocrinology. 2 p.

    Research output: Contribution to journal › Editorial › Research › peer-review

  22. Published

    With obesity becoming the new normal, what should we do? Volume II

    Tziomalos, K., Kilpeläinen, Tuomas O. & Samaras, K., 2022, In: Frontiers in Endocrinology. 13, 3 p., 1119910.

    Research output: Contribution to journal › Editorial › Research

  23. Published

    Women with bulimia nervosa exhibit attenuated secretion of glucagon-like peptide 1, pancreatic polypeptide, and insulin in response to a meal

    Naessén, S., Carlström, K., Holst, Jens Juul, Hellström, P. M. & Hirschberg, A. L., 2011, In: American Journal of Clinical Nutrition. 94, 4, p. 967-972 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Women with prior gestational diabetes mellitus and prediabetes are characterised by a decreased incretin effect

    Foghsgaard, S., Vedtofte, L., Andreasen, C., Andersen, E. S., Bahne, E., Bagger, J. I., Svare, J. A., Holst, Jens Juul, Clausen, Tine Dalsgaard, Mathiesen, Elisabeth, Damm, Peter, Knop, Filip Krag & Vilsbøll, Tina, Jul 2017, In: Diabetologia. 60, 7, p. 1344-1353 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19·1 million participants

    Linneberg, Allan René, Sørensen, Thorkild I.A., Ängquist, Lars & NCD Risk Factor Collaboration (NCD-RisC), N. R. F. C. (., 2017, In: The Lancet. 389, 10064, p. 37-55 19 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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