Novo Nordisk Foundation Center for Basic Metabolic Research

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  1. Published

    A second update on mapping the human genetic architecture of COVID-19

    Kanai, M., Andrews, S., Cordioli, M., Stevens, C., Neale, B. M., Daly, M., Ganna, A., Pathak, G. A., Ellinghaus, D., Banasik, K., Brunak, S., Pedersen, O. B., Westergaard, D., Sequeros, C. B., Nissen, J., Feldt-Rasmussen, U., Grønbæk, K., Ostrowski, S. R., Guindo-Martinez, M., Garcia, S. M. & 70 others, Hjalgrim, Henrik, Admin team lead, A. T. L., Admin team member, A. T. M., Analysis team lead, A. T. L., Analysis team member, A. T. M., Data collection lead, D. C. L., Data collection member, D. C. M., Manuscript analysis team lead, M. A. T. L., Manuscript analysis team members: Mendelian randomization, M. A. T. M. M. R., Manuscript analysis team members: methods development, M. A. T. M. M. D., Manuscript analysis team members: phenome-wide association study, M. A. T. M. P. A. S., Manuscript analysis team members: principal component projection, gene prioritization, M. A. T. M. P. C. P. G. P., Project management lead, P. M. L., Scientific communication lead, S. C. L., Scientific communication member, S. C. M., Writing group lead, W. G. L., Writing group member, W. G. M., 23andMe, 2., Adolescent brain and cognitive development study, A. B. A. C. D. S., Analysis group, A. G., Armenia_Covid-19hg, A., Assessment of the influence of clinical, functional, immunological and genetic factors on the severity of the course of coronavirus infection with SARS-CoV-2 and post-COVID syndrome, A. O. T. I. O. C. F. I. A. G. F. O. T. S. O. T. C. O. C. I. W. S. A. P. S., Avon Longitudinal Study of Parents and Children (ALSPAC), A. L. S. O. P. A. C. (., BelCovid, B., Biobanque Quebec COVID19, B. Q. C., BioVU, B., Bonn Study of COVID-19 Genetics, B. S. O. C. G., CGEn HostSeq—Canadian COVID-19 Human Host Genome Sequencing Databank, C. H. C. H. H. G. S. D., Colorado Center for Personalized Medicine—CCPM, C. C. F. P. M., COMRI/Virology Study, C. S., Covid19 Ioannina Biobank, C. I. B., COVID19-Host(a)ge, C., Covid19hg-CL, C., Danish COVID-19 Genomic Consortium, D. C. G. C., Egypt hgCOVID hub, E. H. H., EraCORE, E., FinnGen, F., French hgCOVID, F. H., GCAT. Genomes For Life, G. G. F. L., Genes & Health, G. &. H., Genetic influences on severity of COVID-19 illness in Korea, G. I. O. S. O. C. I. I. K., GenOMICC, G., Genotek COVID-19 study, G. C. S., Helix Exome+ COVID-19 Phenotypes, H. E. C. P., Host Genetic Factors for COVID-19 Severity and Outcome in Western Indian Population, H. G. F. F. C. S. A. O. I. W. I. P., Host Genetics in COVID Cohorts of Mixed ancestry from Mexico, H. G. I. C. C. O. M. A. F. M., Japan Coronavirus Taskforce, J. C. T., Japan NCGM-COVID19, J. N., Jordan COVID-19 Host Genomics Initiative (JCHGI), J. C. H. G. I. (., Leadership, L., Lung eQTL Consortium, L. E. C., Mass General Brigham—Host Vulnerability to COVID-19, M. G. B. V. T. C., MexGen-COVID, M., Pa-COVID-19, P., Project management group, P. M. G., Project management support, P. M. S., Qatar Genome Program, Q. G. P., SARS-CoV-2 and Host Genome sequencing, S. A. H. G. S., Scientific communication group, S. C. G., Search for Genomic Markers Predicting the Severity of the response to COVID-19, S. F. G. M. P. T. S. O. T. R. T. C., Spanish COalition to Unlock Research on host GEnetics on COVID-19 (SCOURGE), S. C. T. U. R. O. H. G. O. C. (., The Danish Blood Donor Study, T. D. B. D. S., The Genetic Predisposition to severe COVID-19, T. G. P. T. S. C., Tirschenreuth Study (TiKoco), T. S. (., UCLA Precision Health COVID-19 Host Genomics Biobank, U. P. H. C. H. G. B., UK Biobank, U. B., Variability in Immune Response Genes and Severity of SARS-CoV-2 Infection (INMUNGEN-CoV2 study), V. I. I. R. G. A. S. O. S. I. (. S., Website development, W. D., Writing Group, W. G. & The COVID-19 Host Genetics Initiative, T. C. H. G. I., 2023, In: Nature. 621, 7977, p. E7-E26 23 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  2. Published

    A semaphorin-plexin-Rasal1 signaling pathway inhibits gastrin expression and protects against peptic ulcers

    Xu, R., Höß, C., Swiercz, J. M., Brandt, D. T., Lutz, V., Petersen, N., Li, R., Zhao, D., Oleksy, A., Creigh-Pulatmen, T., Trokter, M., Fedorova, M., Atzberger, A., Strandby, R. B., Olsen, A. A., Achiam, M. P., Matthews, D., Huber, M., Gröne, H-J., Offermanns, S. & 1 others, Worzfeld, T., 2022, In: Science Translational Medicine. 14, 654, eabf1922.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    A short-read multiplex sequencing method for reliable, cost-effective and high-throughput genotyping in large-scale studies: [plus] Erratum

    Cao, H., Wang, Y., Zhang, W., Chai, X., Zhang, X., Chen, S., Yang, F., Zhang, C., Guo, Y., Liu, Y., Tang, Z., Chen, C., Xue, Y., Zhen, H., Xu, Y., Rao, B., Liu, T., Zhao, M., Zhang, W., Li, Y. & 6 others, Zhang, X., Tellier, L. C. A. M., Krogh, Anders, Kristiansen, Karsten, Wang, J. & Li, J., 2013, In: Human Mutation. 34, 12, p. 1715-1720 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    A single nucleotide polymorphism within the acetyl-coenzyme A carboxylase beta gene is associated with proteinuria in patients with type 2 diabetes

    Maeda, S., Kobayashi, M., Araki, S., Babazono, T., Freedman, B. I., Bostrom, M. A., Cooke, J. N., Toyoda, M., Umezono, T., Tarnow, L., Hansen, T., Gaede, P., Jorsal, A., Ng, D. P. K., Ikeda, M., Yanagimoto, T., Tsunoda, T., Unoki, H., Kawai, K., Imanishi, M. & 11 others, Suzuki, D., Shin, H. D., Park, K. S., Kashiwagi, A., Iwamoto, Y., Kaku, K., Kawamori, R., Parving, H., Bowden, D. W., Pedersen, Oluf Borbye & Nakamura, Y., 1 Jan 2010, In: P L o S Genetics. 6, 2, p. e1000842

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    A single supplement of a standardised bilberry (Vaccinium myrtillus L.) extract (36 % wet weight anthocyanins) modifies glycaemic response in individuals with type 2 diabetes controlled by diet and lifestyle

    Hoggard, N., Cruickshank, M., Moar, K., Bestwick, C., Holst, Jens Juul, Russell, W. & Horgan, G., 2013, In: Journal of Nutritional Science. 2, 9 p., e22.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    A single-cell atlas of human and mouse white adipose tissue

    Emont, M. P., Jacobs, C., Essene, A. L., Pant, D., Tenen, D., Colleluori, G., Di Vincenzo, A., Jørgensen, A. M., Dashti, H., Stefek, A., McGonagle, E., Strobel, S., Laber, S., Agrawal, S., Westcott, G. P., Kar, A., Veregge, M. L., Gulko, A., Srinivasan, H., Kramer, Z. & 18 others, De Filippis, E., Merkel, E., Ducie, J., Boyd, C. G., Gourash, W., Courcoulas, A., Lin, S. J., Lee, B. T., Morris, D., Tobias, A., Khera, A. V., Claussnitzer, M., Pers, Tune H, Giordano, A., Ashenberg, O., Regev, A., Tsai, L. T. & Rosen, E. D., 2022, In: Nature. 603, p. 926-933

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    A single-cell, time-resolved profiling of Xenopus mucociliary epithelium reveals nonhierarchical model of development

    Lee, J., Møller, A. F., Chae, S., Bussek-Sedzinski, Alexandra Maria, Park, T. J., Kim, Y., Lee, H. S., Pers, Tune H, Kwon, T., Sedzinski, Jakub & Natarajan, K. N., 2023, In: Science Advances. 9, 14, p. eadd5745 23 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    A statistical framework for powerful multi-trait rare variant analysis in large-scale whole-genome sequencing studies

    Li, X., Chen, H., Selvaraj, M. S., Van Buren, E., Zhou, H., Wang, Y., Sun, R., McCaw, Z. R., Yu, Z., Arnett, D. K., Bis, J. C., Blangero, J., Boerwinkle, E., Bowden, D. W., Brody, J. A., Cade, B. E., Carson, A. P., Carlson, J. C., Chami, N., Chen, Y-D. I. & 31 others, Curran, J. E., de Vries, P. S., Fornage, M., Franceschini, N., Freedman, B. I., Gu, C., Heard-Costa, N. L., He, J., Hou, L., Hung, Y., Irvin, M. R., Kaplan, R. C., Kardia, S. L. R., Kelly, T., Konigsberg, I., Kooperberg, C., Kral, B. G., Li, C., Loos, Ruth, Mahaney, M. C., Martin, L. W., Mathias, R. A., Minster, R. L., Mitchell, B. D., Montasser, M. E., Morrison, A. C., Palmer, N. D., Peyser, P. A., Psaty, B. M., Raffield, L. M. & NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, N. T. F. P. M. (. C., 2023, bioRxiv, 71 p.

    Research output: Working paper › Preprint › Research

  9. Published

    A study of associations between early DHA status and fatty acid desaturase (FADS) SNP and developmental outcomes in children of obese mothers

    Andersen, K. R., Harsløf, L. B. S., Schnurr, T. M., Hansen, Torben, Hellgren, L. I., Michaelsen, Kim F. & Lauritzen, Lotte, 2017, In: The British Journal of Nutrition. 117, 2, p. 278-286 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    A systems biology approach to study non-alcoholic fatty liver (NAFL) in women with obesity

    Meijnikman, A. S., Lappa, D., Herrema, H., Aydin, O., Krautkramer, K. A., Tremaroli, V., Olofsson, L. E., Lundqvist, A., Bruin, S., Acherman, Y., Verheij, J., Hjorth, Siv Annegrethe, Gerdes, V. E. A., Schwartz, Thue W., Groen, A. K., Bäckhed, F., Nielsen, J. & Nieuwdorp, M., 2022, In: iScience. 25, 8, 18 p., 104828.

    Research output: Contribution to journal › Journal article › Research › peer-review

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