Novo Nordisk Foundation Center for Basic Metabolic Research

  1. Published

    Glucose-Dependent miR-125b Is a Negative Regulator of β-Cell Function

    Cheung, R., Pizza, G., Chabosseau, P., Rolando, D., Tomas, A., Burgoyne, T., Wu, Z., Salowka, A., Thapa, A., Macklin, A., Cao, Y., Nguyen-Tu, M. S., Dickerson, M. T., Jacobson, D. A., Marchetti, P., Shapiro, J., Piemonti, L., de Koning, E., Leclerc, I., Bouzakri, K. & 4 others, Sakamoto, Kei, Smith, D. M., Rutter, G. A. & Martinez-Sanchez, A., 2022, In: Diabetes. 71, 7, p. 1525-1545 21 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Glucose-Lowering Effects and Low Risk of Hypoglycemia in Patients With Maturity-Onset Diabetes of the Young When Treated With a GLP-1 Receptor Agonist: A Double-Blind, Randomized, Crossover Trial

    Ostoft, S. H., Bagger, J. I., Hansen, Torben, Pedersen, Oluf Borbye, Faber, Jens, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, T., 14 Jun 2014, In: Diabetes Care. 37, 7, p. 1797-1805 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Glucose-dependent Insulinotropic Polypeptide: Blood Glucose Stabilizing Effects in Patients With Type 2 Diabetes

    Christensen, Mikkel Bring, Calanna, S., Holst, Jens Juul, Vilsbøll, T. & Knop, Filip Krag, Mar 2014, In: The Journal of clinical endocrinology and metabolism. 99, 3, p. E418-26 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Glucose-dependent insulinotropic peptide and risk of cardiovascular events and mortality: a prospective study

    Jujic, A., Atabaki-Pasdar, N., Nilsson, P. M., Almgren, P., Hakaste, L., Tuomi, T., Berglund, L. M., Franks, P. W., Holst, Jens Juul, Prasad, R. B., Torekov, Signe Sørensen, Ravassa, S., Diez, J., Persson, M., Melander, O., Gomez, M. F., Groop, L., Ahlqvist, E. & Magnusson, M., May 2020, In: Diabetologia. 63, 5, p. 1043-1054

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Glucose-dependent insulinotropic polypeptide: a bifunctional glucose-dependent regulator of glucagon and insulin secretion in humans

    Christensen, M., Vedtofte, L., Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2011, In: Diabetes. 60, 12, p. 3103-9 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Glucose-dependent insulinotropic polypeptide (GIP) and cardiovascular disease

    Heimbürger, S. M., Bergmann, N. C., Augustin, R., Gasbjerg, Lærke Smidt, Christensen, Mikkel Bring & Knop, Filip Krag, 2020, In: Peptides. 125, 8 p., 170174.

    Research output: Contribution to journalReviewResearchpeer-review

  7. Published

    Glucose-dependent insulinotropic polypeptide (GIP) contributes to sitagliptin-mediated improvement of beta cell function in patients with type 2 diabetes

    Stensen, S., Gasbjerg, Lærke Smidt, Rosenkilde, Mette, Hartmann, Bolette, Vilsbøll, Tina, Holst, Jens Juul, Christensen, M. B. & Knop, Filip Krag, 2021, In: Diabetologia. 64, SUPPL 1, p. 95-95 179.

    Research output: Contribution to journalConference abstract in journalResearch

  8. Published

    Glucose-dependent insulinotropic polypeptide (GIP) induces lipolysis during stable basal insulin substitution and hyperglycemia in men with type 1 diabetes: a randomized, double-blind, placebo-controlled, crossover clinical trial

    Heimburger, S. M., Nielsen, C. N., Calanna, S., Holst, Jens Juul, Vilsbøll, Tina, Knop, Filip Krag & Christensen, Mikkel Bring, 2022, In: Diabetes, Obesity and Metabolism. 24, 1, p. 142-147

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Glucose-dependent insulinotropic polypeptide (GIP) is associated with lower LDL but unhealthy fat distribution, independent of insulin: The ADDITION-PRO study

    Møller, C. L., Vistisen, D., Færch, K., Johansen, N. B., Witte, D. R., Jonsson, Anna Elisabet, Pedersen, Oluf Borbye, Hansen, Torben, Lauritzen, T., Jørgensen, M. E., Torekov, Signe Sørensen & Holst, Jens Juul, Feb 2016, In: Journal of Clinical Endocrinology and Metabolism. 101, 2, p. 485– 493 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Glucose-dependent insulinotropic polypeptide (GIP) receptor antagonists as anti-diabetic agents

    Gasbjerg, Lærke Smidt, Gabe, M. B. N., Hartmann, Bolette, Christensen, Mikkel Bring, Knop, Filip Krag, Holst, Jens Juul & Rosenkilde, Mette, Feb 2018, In: Peptides. 100, p. 173-181

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Glucose-dependent insulinotropic polypeptide has impaired effect on abdominal, subcutaneous adipose tissue metabolism in obese subjects

    Asmar, M., Simonsen, L., Arngrim, N., Holst, Jens Juul, Dela, Flemming & Bülow, J., 2013, In: International journal of obesity (2005). 38, 2, p. 259-65 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Glucose-dependent insulinotropic polypeptide inhibits bone resorption in humans

    Nissen, A., Christensen, Mikkel Bring, Knop, Filip Krag, Vilsbøll, T., Holst, Jens Juul & Hartmann, Bolette, Nov 2014, In: The Journal of clinical endocrinology and metabolism. 99, 11, p. E2325-9 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Glucose-dependent insulinotropic polypeptide promotes lipid deposition in subcutaneous adipocytes in obese type 2 diabetes patients: a maladaptive response

    Thondam, S. K., Daousi, C., Wilding, J. P. H., Holst, Jens Juul, Ameen, G. I., Yang, C., Whitmore, C., Mora, S. & Cuthbertson, D. J., 1 Mar 2017, In: American Journal of Physiology: Endocrinology and Metabolism. 312, 3, p. E224-E233

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Glucose-dependent insulinotropic polypeptide receptor antagonist treatment causes a reduction in weight gain in ovariectomised high fat diet-fed mice

    Boer, G. A., Dal, Jenna Elizabeth Hunt, Gabe, M. B. N., Windeløv, Johanne Agerlin, Sparre-Ulrich, A. H., Hartmann, Bolette, Holst, Jens Juul & Rosenkilde, Mette, 2022, In: British Journal of Pharmacology. 179, 18, p. 4486-4499

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Glucose-lowering effects and mechanisms of the bile acid-sequestering resin sevelamer

    Brønden, A., Mikkelsen, K., Sonne, D. P., Hansen, M., Våben, C., Gabe, M. N., Rosenkilde, Mette, Tremaroli, V., Wu, H., Bäckhed, F., Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, Jul 2018, In: Diabetes, Obesity and Metabolism. 20, 7, p. 1623-1631

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Glukagonlignende peptid 1-receptoragonister til behandling af type 2-diabetes

    Andersen, A., Christensen, A. S., Knop, Filip Krag & Vilsbøll, Tina, 2022, In: Ugeskrift for Laeger. 181, 2, V10180725.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Glutamate prevents intestinal atrophy via luminal nutrient sensing in a mouse model of total parenteral nutrition

    Xiao, W., Feng, Y., Holst, Jens Juul, Hartmann, Bolette, Yang, H. & Teitelbaum, D. H., May 2014, In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 28, 5, p. 2073-87 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Glutamate rich Plasmodium falciparum antigen (GLURP)

    Høgh, Birthe, Thompson, R., Zakiuddin, I. S., Boudin, C. & Borre, M., Jul 1993, In: Parassitologia. 35 Suppl, p. 47-50 4 p.

    Research output: Contribution to journalReviewResearchpeer-review

  19. Published

    Glutamine Regulates Skeletal Muscle Immunometabolism in Type 2 Diabetes

    Dollet, L., Kuefner, M., Caria, E., Rizo-Roca, D., Pendergrast, L., Abdelmoez, A. M., Karlsson, H. K., Kellezi, Emilie Dalbram, Treebak, Jonas Thue, Harada, J., Näslund, E., Rydén, M., Zierath, Juleen R, Pillon, N. J. & Krook, A., 2022, In: Diabetes. 71, 4, p. 624-636

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Glutamine reduces postprandial glycemia and augments the glucagon-like peptide-1 response in type 2 diabetes patients

    Samocha-Bonet, D., Wong, O., Synnott, E., Piyaratna, N., Douglas, A., Gribble, F. M., Holst, Jens Juul, Chisholm, D. J. & Greenfield, J. R., Jul 2011, In: Journal of Nutrition. 141, 7, p. 1233-1238 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Glycaemic control and weight loss with semaglutide in type 2 diabetes

    Madsbad, Sten & Holst, Jens Juul, May 2017, In: The Lancet Diabetes and Endocrinology. 5, 5, p. 315-317 3 p.

    Research output: Contribution to journalLetterResearchpeer-review

  22. Published

    Glycemic effects and safety of L-Glutamine supplementation with or without sitagliptin in type 2 diabetes patients-a randomized study

    Samocha-Bonet, D., Chisholm, D. J., Gribble, F. M., Coster, A. C. F., Carpenter, K. H., Jones, G. R. D., Holst, Jens Juul & Greenfield, J. R., 2014, In: PloS one. 9, 11, p. 1-7 7 p., e113366.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Glycerol-3-phosphate acyltransferase-4-deficient mice are protected from diet-induced insulin resistance by the enhanced association of mTOR and rictor

    Zhang, C., Cooper, D. E., Grevengoed, Trisha Jean, Li, L. O., Klett, E. L., Eaton, J. M., Harris, T. E. & Coleman, R. A., 1 Aug 2014, In: American Journal of Physiology: Endocrinology and Metabolism. 307, 3, p. E305-15

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Godkendelse af personlig medicin

    Sørensen, Thorkild I.A., 2018, In: Ugeskrift for Laeger. 180, p. 1054 1 p., V69798 .

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Gq and Gs signaling acting in synergy to control GLP-1 secretion

    Pedersen, M. H., Ekberg, J. H., Engelstoft, M. S., Timshel, P., Madsen, A. N. & Schwartz, Thue W., Jul 2017, In: Molecular and Cellular Endocrinology. 449, p. 64-73

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Grandpaternal-induced transgenerational dietary reprogramming of the unfolded protein response in skeletal muscle

    Alm, P. S., de Castro Barbosa, T., Barrès, Romain, Krook, A. & Zierath, Juleen R, Jul 2017, In: Molecular Metabolism. 6, 7, p. 621-630 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Greater glucagon-like peptide-1 responses to oral glucose are associated with lower central and peripheral blood pressures

    Lundgren, J. R., Faerch, K., Witte, D. R., Jonsson, Anna Elisabet, Pedersen, Oluf Borbye, Hansen, Torben, Lauritzen, T., Holst, Jens Juul, Vistisen, D., Jorgensen, M. E., Torekov, Signe Sørensen & Johansen, N. B., 2019, In: Cardiovascular Diabetology. 18, 1, 9 p., 130.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Greenlandic Inuit show genetic signatures of diet and climate adaptation

    Fumagalli, M., Moltke, Ida, Grarup, N., Racimo, F., Bjerregaard, P., Jørgensen, M. E., Korneliussen, Thorfinn Sand, Gerbault, P., Skotte, L., Linneberg, Allan René, Christensen, C., Brandslund, I., Jørgensen, T., Huerta-Sánchez, E., Schmidt, E. B., Pedersen, Oluf Borbye, Hansen, T., Albrechtsen, Anders & Nielsen, Rasmus, 2015, In: Science (New York, N.Y.). 349, 6254, p. 1343-1347 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Grey-box modelling of pharmacokinetic/pharmacodynamic systems

    Tornøe, C. W., Jacobsen, Judith Lone, Pedersen, Oluf Borbye, Hansen, Torben & Madsen, H. T., 2004, In: Journal of Pharmacokinetics and Pharmacodynamics. 31, 5, p. 401-17 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Growth Hormone Antagonists. A Pharmacological Tool in Present and Future Therapies

    Kopchick, J. J., Qiu, L., Gosney, E., Keller, C., Palmer, A. & Sankaran, S., 1 Dec 2005, The Somatotrophic Axis in Brain Function. Elsevier Science Inc., p. 313-326 14 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  31. Published

    Growth hormone acts along the PPARγ-FSP27 axis to stimulate lipolysis in human adipocytes

    Sharma, V. M., Vestergaard, E. T., Jessen, N., Kolind-Thomsen, P., Nellemann, B., Nielsen, Thomas Svava, Vendelbo, M. H., Møller, N., Sharma, R., Lee, K. Y., Kopchick, J. J., Jørgensen, J. O. L. & Puri, V., 2019, In: American Journal of Physiology: Endocrinology and Metabolism. 316, 1, p. E34-E42

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Growth in Total Height and Its Components and Cardiometabolic Health in Childhood

    Haugaard, L. K., Baker, J. L., Perng, W., Belfort, M. B., Rifas-Shiman, S. L., Switkowski, K., Oken, E. & Gillman, M. W., 23 Sep 2016, In: PLOS ONE. 11, 9, p. 1-15 15 p., e0163564.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Growth in height in childhood and risk of coronary heart disease in adult men and women

    Silventoinen, K., Baker, J. L. & Sørensen, Thorkild I.A., 2012, In: P L o S One. 7, 1, p. e30476

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Guanylin and uroguanylin mRNA expression is increased following Roux-en-Y gastric bypass, but guanylins do not play a significant role in body weight regulation and glycemic control

    Fernandez-Cachon, M. L., Pedersen, S. L., Rigbolt, K. T., Zhang, C., Fabricius, K., Hansen, H. H., Elster, L., Fink, L. N., Schäfer, M., Rhee, N. A., Langholz, E., Wandall, E., Friis, S. U., Vilmann, P., Kristiansen, V. B., Schmidt, C., Schreiter, K., Breitschopf, K., Hübschle, T., Jorsal, T. & 6 others, Vilsbøll, Tina, Schmidt, T., Theis, S., Knop, Filip Krag, Larsen, P. J. & Jelsing, J., Mar 2018, In: Peptides. 101, p. 32-43 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Guidelines: Surgical or medical therapy for patients with obesity and T2DM?

    Madsbad, Sten & Holst, Jens Juul, 1 Sep 2016, In: Nature Reviews Endocrinology. 12, 9, p. 500-502 3 p.

    Research output: Contribution to journalComment/debateCommunication

  36. Published

    Gut: a key player in the pathogenesis of type 2 diabetes?

    Muscogiuri, G., Balercia, G., Barrea, L., Cignarelli, A., Giorgino, F., Holst, Jens Juul, Laudisio, D., Orio, F., Tirabassi, G. & Colao, A., 2018, In: Critical Reviews in Food Science and Nutrition. 58, 8, p. 1294–1309

    Research output: Contribution to journalReviewResearchpeer-review

  37. Published

    Gut Hormones and Their Effect on Bone Metabolism. Potential Drug Therapies in Future Osteoporosis Treatment

    Schiellerup, S. P., Skov-Jeppesen, Kirsa, Windeløv, Johanne Agerlin, Svane, M. S., Holst, Jens Juul, Hartmann, Bolette & Rosenkilde, Mette, 2019, In: Frontiers in Endocrinology. 10, 13 p., 75.

    Research output: Contribution to journalReviewResearchpeer-review

  38. Published

    Gut Microbiota Contribution to Weight-Independent Glycemic Improvements after Gastric Bypass Surgery

    Hankir, M. K., Kovatcheva-Datchary, P., Springer, R., Hoffmann, A., Vogel, J., Seyfried, F. & Arora, Tulika, 2023, In: Microbiology Spectrum. 11, 3, 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Gut Mucosal Gene Expression and Metabolic Changes After Roux-en-Y Gastric Bypass Surgery

    Jorsal, T., Christensen, M. M., Mortensen, B., Nygaard, E. B., Zhang, C., Rigbolt, K., Wandall, E., Langholz, E., Friis, S., Worm, D., Floyd, A., Helgstrand, F., Støving, R. K., Aldries, A. R., Juhl, C. B., Østergaard, T., Rydborg, T., Forman, J. L., Sørensen, F., Schmidt, T. & 9 others, Falkenhahn, M., Musholt, P. B., Theis, S., Larsen, P. J., Rehfeld, Jens Frederik, Vrang, N., Jelsing, J., Vilsbøll, Tina & Knop, Filip Krag, 2020, In: Obesity. 28, 11, p. 2163-2174 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Gut bacterial metabolism contributes to host global purine homeostasis

    Kasahara, K., Kerby, R. L., Zhang, Q., Pradhan, M., Mehrabian, M., Lusis, A. J., Bergström, G., Bäckhed, F. & Rey, F. E., 2023, In: Cell Host and Microbe. 31, 6, p. 1038-1053.e10

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Gut hormone release after gastric bypass depends on the length of the biliopancreatic limb

    Patrício, B. G., Morais, T., Guimarães, M., Veedfald, Simon, Hartmann, Bolette, Hilsted, Linda, Holst, Jens Juul, Nora, M. & Monteiro, M. P., 1 May 2019, In: International Journal of Obesity. 43, 5, p. 1009-1018

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Gut hormone secretion, gastric emptying and glucose absorption after frequently sampled oral glucose and liquid mixed meal tests in young men: [Meeting Abstract]

    Veedfald, Simon, Rehfeld, Jens Frederik, vanHall, G., Svendsen, Lars Bo & Holst, Jens Juul, 2020, In: Neurogastroenterology and Motility. 32, SI, p. 56 1 p., 146.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  43. Published

    Gut hormones and gastric bypass

    Holst, Jens Juul, 2016, In: Cardiovascular Endocrinology. 5, 3, p. 69-74 6 p.

    Research output: Contribution to journalReviewResearchpeer-review

  44. Published

    Gut hormones and intestinal function

    Holst, Jens Juul & Schmidt, P., 1994, The Gut as an Endocrine Organ. Clinics in Endocrinology and Metabolism, Vol 8. Bailliere, p. 137-164

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  45. Published

    Gut hormones, early dumping and resting energy expenditure in patients with good and poor weight loss response after Roux-en-Y gastric bypass

    Dirksen, C., Jørgensen, N. B., Bojsen-Møller, K. N., Kielgast, U., Jacobsen, S. H., Clausen, T. R., Worm, Dorte, Hartmann, Bolette, Rehfeld, Jens Frederik, Damgaard, Morten, Madsen, J. L., Madsbad, Sten, Holst, Jens Juul & Hansen, D. L., 19 Feb 2013, In: International Journal of Obesity. 37, p. 1452-1459 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Gut microbial characteristics in poor appetite and undernutrition: a cohort of older adults and microbiota transfer in germ-free mice

    Fluitman, K. S., Davids, M., Olofsson, L. E., Wijdeveld, M., Tremaroli, V., Keijser, B. J. F., Visser, M., Bäckhed, F., Nieuwdorp, M. & IJzerman, R. G., 2022, In: Journal of Cachexia, Sarcopenia and Muscle. 13, 4, p. 2188-2201

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Gut microbial metabolites as multi-kingdom intermediates

    Krautkramer, K. A., Fan, J. & Backhed, F., 2021, In: Nature Reviews. Microbiology. 19, p. 77-94 18 p.

    Research output: Contribution to journalReviewResearchpeer-review

  48. Published

    Gut microbiome development along the colorectal adenoma-carcinoma sequence

    Feng, Q., Liang, S., Jia, H., Stadlmayr, A., Tang, L., Lan, Z., Zhang, D., Xia, H., Xu, X., Jie, Z., Su, L., Li, X., Li, X., Li, J., Xiao, L., Huber-Schönauer, U., Niederseer, D., Xu, X., Al-Aama, J. Y., Yang, H. & 6 others, Wang, J., Kristiansen, Karsten, Arumugam, Mani, Tilg, H., Datz, C. & Wang, J., 2015, In: Nature Communications. 6, 13 p., 6528.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Gut microbiota composition in patients with newly diagnosed bipolar disorder and their unaffected first-degree relatives

    Coello, K., Hansen, T. H., Sørensen, N., Munkholm, K., Kessing, Lars Vedel, Pedersen, Oluf Borbye & Vinberg, Maj, 2019, In: Brain, Behavior, and Immunity. 75, p. 112-118

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Gut microbiota dysbiosis is associated with malnutrition and reduced plasma amino acid levels: Lessons from genome-scale metabolic modeling

    Kumar, M., Ji, B., Babaei, P., Das, P., Lappa, D., Ramakrishnan, G., Fox, T. E., Haque, R., Petri, W. A., Backhed, F. & Nielsen, J., 2018, In: Metabolic Engineering. 49, p. 128-142

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Gut microbiota in human metabolic health and disease

    Fan, Yong & Pedersen, Oluf Borbye, 2021, In: Nature Reviews. Microbiology. 19, p. 55-71 17 p.

    Research output: Contribution to journalReviewResearchpeer-review

  52. Published

    Gut microbiota may have influence on glucose and lipid metabolism.

    Mikkelsen, K. H., Nielsen, M. F., Tvede, M., Hansen, Torben, Pedersen, Oluf Borbye, Holst, Jens Juul, Vilsbøll, T. & Knop, Filip Krag, 11 Nov 2013, In: Ugeskrift for Laeger. 175, 46, p. 2785-2788 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Gut microbiota of obese subjects with Prader-Willi syndrome is linked to metabolic health

    Olsson, L. M., Poitou, C., Tremaroli, V., Coupaye, M., Aron-Wisnewsky, J., Bäckhed, F., Clément, K. & Caesar, R., 2020, In: Gut. 69, 7, 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Gut microbiota profile and selected plasma metabolites in type 1 diabetes without and with stratification by albuminuria

    Winther, S. A., Henriksen, P., Vogt, J. K., Hansen, T. H., Ahonen, L., Suvitaival, T., Zobel, E. H., Frimodt-Møller, M., Hansen, T. W., Hansen, Torben, Parving, H., Legido-Quigley, C., Rossing, Peter & Pedersen, Oluf Borbye, 2020, In: Diabetologia. 63, p. 2713-2724 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    Gut microbiota regulates maturation of the adult enteric nervous system via enteric serotonin networks

    De Vedder, F., Grasset, E., Holm, L. M., Karsenty, G., Macpherson, A. J., Olofsson, L. E. & Backhed, F., 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 25, p. 6458-6463

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids

    Nakamura, K., Saredi, G., Becker, J. R., Foster, B. M., Nguyen, N. V., Beyer, T. E., Cesa, L. C., Faull, P. A., Lukauskas, S., Frimurer, Thomas Michael, Chapman, J. R., Bartke, T. & Groth, Anja, 2019, In: Nature Cell Biology. 21, 3, p. 311-318

    Research output: Contribution to journalLetterResearchpeer-review

  57. Published

    HBD-2 mutations are associated with childhood asthma and prophylactic hBD-2 application prevents asthma in mice

    Borchers, N., Santos-Valente, E., Toncheva, A. A., Wehkamp, J., Franke, A., Gaertner, V. D., Nordkild, P., Genuneit, J., Jensen, Benjamin Anderschou Holbech & Kabesch, M., 2021, In: European Respiratory Journal. 58, Suppl. 65, 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    HDAC Inhibitor-Mediated Beta-Cell Protection Against Cytokine-Induced Toxicity Is STAT1 Tyr701 Phosphorylation Independent

    Dahllöf, M. S., Christensen, D. P., Harving, M., Wagner, B. K., Mandrup-Poulsen, Thomas & Lundh, M., 13 Jan 2015, In: Journal of Interferon & Cytokine Research. 35, 1, p. 63-70 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    HDAC3 inhibition rescues pancreatic beta cells from glucolipotoxicity and improves insulin secretion in obese diabetic rats

    Lundh, M., Galbo, T., Wagner, F. F., Christensen, D. P., Walpita, D., Gale, J. P., Zhang, Y., Hooker, J., Shulman, G. I., Mandrup-Poulsen, Thomas, Holson, E. B. & Wagner, B. K., Sep 2013, In: Diabetologia. 56, 1 suppl, p. S219-S219

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    HDACs class II-selective inhibition alters nuclear receptor-dependent differentiation

    Nebbioso, A., Dell'Aversana, C., Bugge, A. S., Sarno, R., Valente, S., Rotili, D., Manzo, F., Teti, D., Mandrup, S., Ciana, P., Maggi, A., Mai, A., Gronemeyer, H. & Altucci, L., 2010, In: Journal of Molecular Endocrinology. 45, 4, p. 219-28 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published

    HIV infection drives interferon signaling within intestinal SARS-CoV-2 target cells

    Fardoos, R., Asowata, O. E., Herbert, N., Nyquist, S. K., Zungu, Y., Singh, A., Ngoepe, A., Mbano, I. M., Mthabela, N., Ramjit, D., Karim, F., Kuhn, W., Madela, F. G., Manzini, V. T., Anderson, F., Berger, B., Pers, Tune H, Shalek, A. K., Leslie, A. & Kløverpris, Henrik Nyhus, 2021, In: JCI insight. 6, 16, e148920.

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. Published

    HOODS: finding context-specific neighborhoods of proteins, chemicals and diseases

    Palleja, A. & Jensen, Lars Juhl, 2015, In: PeerJ. 3, p. 1-10 10 p., e1057.

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    HUMAN SKIN MICROORGANISMS ARE DISTRIBUTED IN BIOFILM AGGREGATES AT WOUND EDGES

    Bay, Lene, Agren, M. S., Poulsen, Steen Seier, Ghathian, K. S. A., Calum, H. & Bjarnsholt, Thomas, 2015, In: Wound Repair and Regeneration. 23, 4, p. A3-A3 1 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  64. Published

    Habitual activity associates with lower fasting and greater glucose-induced GLP-1 response in men

    Janus, C., Vistisen, D., Amadid, H., Witte, D. R., Lauritzen, T., Brage, S., Bjerregaard, A., Hansen, Torben, Holst, Jens Juul, Jørgensen, M. E., Pedersen, Oluf Borbye, Færch, K. & Torekov, Signe Sørensen, 2019, In: Endocrine Connections. 8, 12, p. 1607–1617 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. Published

    Habitual sleep disturbances and migraine: a Mendelian randomization study

    Daghlas, I., Vgontzas, A., Guo, Y., Chasman, D. I., Saxena, R., Pers, Tune H & International Headache Genetics Consortium, I. H. G. C., 2020, In: Annals of Clinical and Translational Neurology. 7, 12, p. 2370-2380 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  66. Published

    Habitual sleep duration is associated with BMI and macronutrient intake and may be modified by CLOCK genetic variants

    Dashti, H. S., Follis, J. L., Smith, C. E., Tanaka, T., Cade, B. E., Gottlieb, D. J., Hruby, A., Jacques, P. F., Lamon-Fava, S., Richardson, K., Saxena, R., Scheer, F. A. J. L., Kovanen, L., Bartz, T. M., Perälä, M-M., Jonsson, A. E., Frazier-Wood, A. C., Kalafati, I-P., Mikkilä, V., Partonen, T. & 34 others, Lemaitre, R. N., Lahti, J., Hernandez, D. G., Toft, Ulla Marie Nørgaard, Johnson, W. C., Kanoni, S., Raitakari, O. T., Perola, M., Psaty, B. M., Ferrucci, L., Grarup, N., Highland, H. M., Rallidis, L., Kähönen, M., Havulinna, A. S., Siscovick, D. S., Räikkönen, K., Jørgensen, T., Rotter, J. I., Deloukas, P., Viikari, J. S. A., Mozaffarian, D., Linneberg, Allan René, Seppälä, I., Hansen, Torben, Salomaa, V., Gharib, S. A., Eriksson, J. G., Bandinelli, S., Pedersen, Oluf Borbye, Rich, S. S., Dedoussis, G., Lehtimäki, T. & Ordovás, J. M., Jan 2015, In: The American Journal of Clinical Nutrition. 101, 1, p. 135-43 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  67. Published

    Handedness in twins according to zygosity and chorion type: a preliminary report

    Derom, C., Thiery, E., Vlietinck, R., Loos, Ruth & Derom, R., Jul 1996, In: Behavior Genetics. 26, 4, p. 407-8 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    Handlingsplan om diabetes

    Pedersen, Oluf Borbye, 2004, In: Ugeskrift for Laeger. 166, 12, p. 1099

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. Published

    Haploinsufficiency of ARHGAP42 is associated with hypertension

    Fjorder, A. S., Rasmussen, Malene Bøgehus, Mehrjouy, M. M., Nazaryan-Petersen, L., Hansen, C., Bak, M., Grarup, N., Nørremølle, Anne, Larsen, Lars Allan, drb459, drb459, Hansen, Torben, Tommerup, Niels & Bache, Iben, 2019, In: European Journal of Human Genetics. 27, 8, p. 1296-1303 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. Published

    Har du let eller svært ved at tage på? Måske skyldes det kalorierne i toilettet

    Lund, Jens, Gerhart-Hines, Zach & Clemmensen, Christoffer, 1 Oct 2020, Videnskab.dk, ForskerZonen.

    Research output: Other contributionNet publication - Internet publicationCommunication

  71. Published

    Harnessing the beneficial properties of adipogenic microbes for improving human health

    Dhurandhar, N. V., Geurts, L., Atkinson, R. L., Casteilla, L., Clement, K., Gerard, P., Vijay-Kumar, M., Nam, J. H., Nieuwdorp, M., Trovato, G., Sørensen, Thorkild I.A., Vidal-Puig, A. & Cani, P. D., 2013, In: Obesity Reviews. 14, 9, p. 721-735 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  72. Published

    Harnessing the power of proteomics in precision diabetes medicine

    Kurgan, Nigel Kilty, Larsen, Jeppe Kjærgaard & Deshmukh, Atul Shahaji, 2024, In: Diabetologia. 67, 5, p. 783–797

    Research output: Contribution to journalReviewResearchpeer-review

  73. Published

    Health care professionals from developing countries report educational benefits after an online diabetes course

    Albrechtsen, Nicolai Jacob Wewer, Poulsen, K. W., Svensson, L. Ø., Jensen, Lasse X, Holst, Jens Juul & Torekov, Signe Sørensen, 31 May 2017, In: B M C Medical Education. 17, 8 p., 97.

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. Published

    Healthcare Burden in Greenland of Gastrointestinal Symptoms in Adults with Inherited Loss of Sucrase-Isomaltase Function

    Andersen, K., Hansen, Torben, Jørgensen, M. E. & Senftleber, N., 2024, In: Application of Clinical Genetics. 17, p. 15-21 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. Published

    Healthy Weight Loss Maintenance with Exercise, Liraglutide, or Both Combined

    Lundgren, J. R., Janus, C., Jensen, Simon Birk Kjær, Juhl, C. R., Olsen, L. M., Christensen, R. M., Svane, M. S., Bandholm, Thomas Quaade, Bojsen-Møller, K. N., Blond, Martin Bæk, Jensen, Jens-Erik Beck, Stallknecht, Bente Merete, Holst, Jens Juul, Madsbad, Sten & Torekov, Signe Sørensen, 6 May 2021, In: New England Journal of Medicine. 384, p. 1719-1730 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  76. Published
  77. Published

    Heavier smoking may lead to a relative increase in waist circumference: evidence for a causal relationship from a Mendelian randomisation meta-analysis. The CARTA consortium

    Morris, R. W., Taylor, A. E., Fluharty, M. E., Bjørngaard, J. H., Åsvold, B. O., Elvestad Gabrielsen, M., Campbell, A., Marioni, R., Kumari, M., Korhonen, T., Männistö, S., Marques-Vidal, P., Kaakinen, M., Cavadino, A., Postmus, I., Husemoen, L. L. N., Skaaby, T., Ahluwalia, T. V. S., Treur, J. L., Willemsen, G. & 42 others, Dale, C., Wannamethee, S. G., Lahti, J., Palotie, A., Räikkönen, K., McConnachie, A., Padmanabhan, S., Wong, A., Dalgård, C., Paternoster, L., Ben-Shlomo, Y., Tyrrell, J., Horwood, J., Fergusson, D. M., Kennedy, M. A., Nohr, E. A., Christiansen, L., Kyvik, K. O., Kuh, D., Watt, G., Eriksson, J. G., Whincup, P. H., Vink, J. M., Boomsma, D. I., Davey Smith, G., Lawlor, D., Linneberg, Allan René, Ford, I., Jukema, J. W., Power, C., Hyppönen, E., Jarvelin, M., Preisig, M., Borodulin, K., Kaprio, J., Kivimaki, M., Smith, B. H., Hayward, C., Romundstad, P. R., Sørensen, Thorkild I.A., Munafò, M. R. & Sattar, N., 2015, In: B M J Open. 5, 8, p. 1-10 10 p., e008808.

    Research output: Contribution to journalJournal articleResearchpeer-review

  78. Published

    Heavy metal exposure causes changes in the metabolic health-associated gut microbiome and metabolites

    Li, Xuan Ji, Brejnrod, A. D., Ernst, M., Rykær, M., Herschend, J., Olsen, N. M. C., Dorrestein, P. C., Rensing, C. & Sørensen, Søren Johannes, 2019, In: Environment International. 126, p. 454-467 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  79. Published

    Height and body-mass index trajectories of school-aged children and adolescents from 1985 to 2019 in 200 countries and territories: a pooled analysis of 2181 population-based studies with 65 million participants

    NCD Risk Factor Collaboration (NCD-RisC), N. R. F. C. (., Afzal, Shoaib, Michaelsen, Kim F., Damsgaard, Camilla Trab, Sørensen, Thorkild I.A. & Ängquist, Lars, 2020, In: Lancet. 396, 10261, p. 1511-1524 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  80. Published

    Height at Ages 7-13 Years in Relation to Developing Type 2 Diabetes Throughout Adult Life

    Bjerregaard, L. G., Jensen, B. W. & Baker, J. L., Jul 2017, In: Paediatric and Perinatal Epidemiology. 31, 4, p. 284-292 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  81. Published

    Hemodynamic Effects of Glucagon: A Literature Review

    Petersen, K. M., Bogevig, S., Holst, Jens Juul, Knop, Filip Krag & Christensen, Mikkel Bring, 2018, In: Journal of Clinical Endocrinology & Metabolism. 103, 5, p. 1804-1812

    Research output: Contribution to journalReviewResearchpeer-review

  82. Published

    Hemoglobin A1c and Fructosamine Evaluated in Patients with Type 2 Diabetes Receiving Peritoneal Dialysis Using Long-Term Continuous Glucose Monitoring

    Bomholt, T., Feldt-Rasmussen, Bo, Butt, Rizwan Ahmed, Borg, Rikke, Sarwary, M. H., Elung-Jensen, T., Almdal, Thomas Peter, Knop, Filip Krag, Nørgaard, Kirsten, Ranjan, A. G., Larsson, A., Rix, M. & Hornum, Mads, 2022, In: Nephron. 146, 2, p. 146-152

    Research output: Contribution to journalJournal articleResearchpeer-review

  83. Published

    Heparin treatment increases thioredoxin interacting protein expression in hepatocellular carcinoma cells

    Gunes, A., Iscan, E., Topel, Hande, Avci, S. T., Gumustekin, M., Erdal, E. & Atabey, N., Aug 2015, In: The International Journal of Biochemistry & Cell Biology. 65, p. 169-81 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  84. Published

    Hepatic Bile Acid Reuptake in the Rat Depends on Bile Acid Conjugation but Not on Agonistic Properties towards FXR and TGR5

    Trammell, Sam, Svenningsen, J. S., Holst, Jens Juul, Gillum, M. P. & Kuhre, Rune Ehrenreich, 2020, In: Molecules. 25, 14 p., 2371.

    Research output: Contribution to journalJournal articleResearchpeer-review

  85. Published

    Hepatic Glucose Production, Ureagenesis, and Lipolysis Quantified using the Perfused Mouse Liver Model

    Winther-Sørensen, Marie, Kemp, I. M., Bisgaard, Hanne Cathrine, Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2023, In: Journal of Visualized Experiments. 2023, 200, e65596.

    Research output: Contribution to journalJournal articleResearchpeer-review

  86. Published

    Hepatic Insulin Clearance in Regulation of Systemic Insulin Concentrations—Role of Carbohydrate and Energy Availability

    Bojsen-Møller, K. N., Lundsgaard, Anne-Marie, Madsbad, Sten, Kiens, Bente & Holst, Jens Juul, Nov 2018, In: Diabetes. 67, 11, p. 2129-2136 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  87. Published

    Hepatic NAD Metabolism Is Dysregulated By an Excessive Supply of Lipids

    Penke, M., Treebak, Jonas Thue, Schuster, S., Gorski, T., Garten, A. & Kiess, W., 2014, In: Endocrine Reviews.

    Research output: Contribution to journalJournal articleResearchpeer-review

  88. Published

    Hepatic NAD salvage pathway is enhanced in mice on a high-fat diet

    Penke, M., Larsen, P. S., Schuster, S., Dall, M., Jensen, Benjamin Anderschou Holbech, Gorski, T., Meusel, A., Richter, S., Vienberg, S. G., Treebak, Jonas Thue, Kiess, W. & Garten, A., 2015, In: Molecular and Cellular Endocrinology. 412, p. 65-72 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  89. Published

    Hepatic NAD+ levels and NAMPT abundance are unaffected during prolonged high-fat diet consumption in C57BL/6JBomTac mice

    Dall, M., Penke, M., Sulek, K., Matz-Soja, M., Holst, Birgitte, Garten, A., Kiess, W. & Treebak, Jonas Thue, 2018, In: Molecular and Cellular Endocrinology. 473, p. 245-256 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  90. Published

    Hepatic expression of lipopolysaccharide- binding protein ( Lbp ) is induced by the gut microbiota through Myd88 and impairs glucose tolerance in mice independent of obesity

    Molinaro, A., Koh, A., Wu, H., Schoeler, M., Faggi, M. I., Carreras, A., Hallen, A., Backhed, F. & Caesar, R., 2020, In: Molecular Metabolism. 37, 9 p., 100997.

    Research output: Contribution to journalJournal articleResearchpeer-review

  91. Published

    Hepatic microbiome in healthy lean and obese humans

    Suppli, M. P., Bagger, J. I., Lelouvier, B., Broha, A., Demant, M., Kønig, M. J., Strandberg, C., Lund, A., Vilsbøll, Tina & Knop, Filip Krag, Aug 2021, In: JHEP Reports. 3, 4, 100299.

    Research output: Contribution to journalJournal articleResearchpeer-review

  92. Published

    Hepatic mitochondrial oxidative phosphorylation is normal in obese patients with and without type 2 diabetes

    Lund, M. T., Kristensen, M. D., Hansen, M., Tveskov, L., Floyd, A. K., Støckel, M., Vainer, B., Poulsen, Steen Seier, Helge, Jørn Wulff, Prats Gavalda, Clara & Dela, Flemming, 6 Apr 2016, In: The Journal of Physiology. 594, 15, p. 4351-4358 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  93. Published

    Hepatic steatosis and glucagon resistance develope in parallel resulting in hyperglucagonaemia and hyperaminoacidaemia

    Winther-Sørensen, Marie, Galsgaard, Katrine Douglas, Santos, A., Pedersen, J., Hassing, Anna Skab, Dall, M., Treebak, Jonas Thue, Kjeldsen, Sasha Alexandra Sampson, Knop, Filip Krag, Werge, M. P., Eriksen, P. L., Vilstrup, H., Gluud, Lise Lotte, Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2020, In: Diabetologia. 63, SUPPL 1, p. S71-S72 142.

    Research output: Contribution to journalConference abstract in journalResearch

  94. Published

    Hepatic transcriptome signatures in patients with varying degrees of nonalcoholic fatty liver disease compared with healthy normal-weight individuals

    Suppli, M. P., Rigbolt, K. T. G., Veidal, S. S., Heeboll, S., Eriksen, P. L., Demant, M., Bagger, J. I., Nielsen, J. C., Oro, D., Thrane, S. W., Lund, A., Strandberg, C., Konig, M. J., Vilsbøll, Tina, Vrang, N., Thomsen, K. L., Gronbaek, H., Jelsing, J., Hansen, H. H. & Knop, Filip Krag, 2019, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 316, 4, p. G462-G472 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. Published

    Hepatitis B virus upregulates host microRNAs that target apoptosis-regulatory genes in an in vitro cell model

    Nielsen, K. O., Jacobsen, K. S., Mirza, A. H., Winther, T. N., Størling, J., Glebe, D., Pociot, Flemming & Høgh, Birthe, 2018, In: Experimental Cell Research. 371, 1, p. 92-103

    Research output: Contribution to journalJournal articleResearchpeer-review

  96. Published

    Hepatocyte MyD88 affects bile acids, gut microbiota and metabolome contributing to regulate glucose and lipid metabolism

    Duparc, T., Plovier, H., Marrachelli, V. G., Van Hul, M., Essaghir, A., Ståhlman, M., Matamoros, S., Geurts, L., Pardo-Tendero, M. M., Druart, C., Delzenne, N. M., Demoulin, J., van der Merwe, S. W., van Pelt, J., Bäckhed, G. F., Monleon, D., Everard, A. & Cani, P. D., 2017, In: Gut. 66, 4, p. 620-632 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  97. Published

    Hepatocyte-specific perturbation of NAD+ biosynthetic pathways in mice induces reversible nonalcoholic steatohepatitis-like phenotypes

    Dall, M., Hassing, Anna Skab, Niu, Lili, Nielsen, Thomas Svava, Ingerslev, L. R., Sulek, K., Trammell, Sam, Gillum, M. P., Barrès, Romain, Larsen, Steen, Poulsen, Steen Seier, Mann, Matthias, Ørskov, Cathrine & Treebak, Jonas Thue, 2021, In: Journal of Biological Chemistry. 297, 6, 26 p., 101388.

    Research output: Contribution to journalJournal articleResearchpeer-review

  98. Published

    Hepatoprotective effects of the long-acting fibroblast growth factor 21 analog PF-05231023 in the GAN diet-induced obese and biopsy-confirmed mouse model of nonalcoholic steatohepatitis

    Nielsen, M. H., Gillum, M. P., Vrang, N., Jelsing, J., Hansen, H. H., Feigh, M. & Oró, D., 2023, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 324, 5, p. G378-G388 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  99. Published

    Heritability of gestational weight gain: a Swedish register-based twin study

    Andersson, E. S., Silventoinen, K., Tynelius, P., Nohr, E. A., Sørensen, Thorkild I.A. & Rasmussen, F., Aug 2015, In: Twin Research and Human Genetics. 18, 4, p. 410-8 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  100. Published

    Heritability of optic disc diameters: a twin study

    Drobnjak, D., Taarnhøj, N. C., Mitchell, P., Wang, J. J., Tan, A., Kessel, Line, Hougaard, J., Sørensen, Thorkild I.A. & Larsen, Michael, 1 Mar 2011, In: Acta Ophthamologica (Online). 89, 2, p. e193-8

    Research output: Contribution to journalJournal articleResearch