Novo Nordisk Foundation Center for Basic Metabolic Research

  1. Published

    Benchmarker: An Unbiased, Association-Data-Driven Strategy to Evaluate Gene Prioritization Algorithms

    Fine, R. S., Pers, Tune H, Amariuta, T., Raychaudhuri, S. & Hirschhorn, J. N., 2019, In: American Journal of Human Genetics. 104, 6, p. 1025-1039

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Benchmarking the HLA typing performance of Polysolver and Optitype in 50 Danish parental trios

    Matey-Hernandez, M. L., Danish Pan Genome Consortium, D. P. G. C., Brunak, Søren, Izarzugaza, J. M. G., Sørensen, L. M., Petersen, Bent, Sibbesen, Jonas Andreas, Liu, S., Belling, K. G., Have, C. T., Bork-Jensen, J., Sun, J., Hansen, Torben, Krogh, Anders, Sørensen, Thorkild I.A., Pedersen, Oluf Borbye, Wang, J., Eiberg, Hans Rudolf Lytchoff & Kristiansen, Karsten, 2018, In: BMC Bioinformatics. 19, p. 1-12 239.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Beneficial impact of intensified multifactorial intervention on risk of stroke: outcome of 21 years of follow-up in the randomised Steno-2 Study

    Gæde, P., Oellgaard, J., Kruuse, Christina Rostrup, Rossing, Peter, Parving, H. & Pedersen, Oluf Borbye, 2019, In: Diabetologia. 62, 9, p. 1575-1580

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Benefit-Risk Assessment of Obesity Drugs: Focus on Glucagon-like Peptide-1 Receptor Agonists

    Christensen, R. M., Juhl, C. R. & Torekov, Signe Sørensen, 2019, In: Drug Safety. 42, 8, p. 957-971 15 p.

    Research output: Contribution to journalReviewResearchpeer-review

  5. Published

    Benefits and Harms of Sodium-Glucose Co-Transporter 2 Inhibitors in Patients with Type 2 Diabetes: A Systematic Review and Meta-Analysis

    Storgaard, H., Gluud, Lise Lotte, Bennett, C., Grøndahl, M. F., Christensen, Mikkel Bring, Knop, Filip Krag & Vilsbøll, Tina, 2016, In: PLOS ONE. 11, 11, 23 p., e0166125.

    Research output: Contribution to journalReviewResearchpeer-review

  6. Published

    Bereavement in early life and later childhood overweight

    Li, J., Olsen, J., Vestergaard, M., Obel, C., Baker, J. L. & Sørensen, Thorkild I.A., 2012, In: Obesity Facts. 5, 6, p. 881-9 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Beta cell dysfunction induced by bone morphogenetic protein (BMP)-2 is associated with histone modifications and decreased NeuroD1 chromatin binding

    Urizar, A. I., Prause, Michala Cecilie Burstein, Ingerslev, L. R., Wortham, M., Sui, Y., Sander, M., Williams, K., Barrès, Romain, Larsen, M. R., Christensen, G. L. & Billestrup, Nils, 2023, In: Cell Death and Disease. 14, 7, 16 p., 399.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Beta-Cell Specific DMT1 KO Protects Islets from Cytokine Induced ROS and Apoptosis

    Hansen, J. B., Heller, S., Madsen, A. N., Holst, Birgitte, Tonnesen, M. F. & Mandrup-Poulsen, Thomas, 2012.

    Research output: Contribution to conferencePosterResearchpeer-review

  9. Published

    Beta-Hydroxybutyrate Suppresses Hepatic Production of the Ghrelin Receptor Antagonist LEAP2

    Holm, Stephanie Kjærulff, Husted, Anna Sofie, Skov, Louise Julie, Morville, T. H., Hagemann, C. A., Jorsal, T., Dall, M., Jakobsen, A., Klein, A. B., Treebak, Jonas Thue, Knop, Filip Krag, Schwartz, Thue W., Clemmensen, Christoffer & Holst, Birgitte, 2022, In: Endocrinology. 163, 6, 13 p., bqac038.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Betydning af sædcellens epigenetik for befrugtning og fosterudvikling

    Saupstad, M., Andersen, E. & Barrès, Romain, 2018, In: Ugeskrift for Laeger. 180, p. 2-5 V02180152.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Biased Gs Versus Gq Proteins and β-Arrestin Signaling in the NK1 Receptor Determined by Interactions in the Water Hydrogen Bond Network

    Valentin-Hansen, L., Frimurer, Thomas Michael, Mokrosinski, J., Holliday, N. D. & Schwartz, Thue W., 2 Oct 2015, In: The Journal of Biological Chemistry. 290, 40, p. 24495-508 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Biased GLP-2 agonist with strong G protein-coupling but impaired arrestin recruitment and receptor desensitization enhances intestinal growth in mice

    Gabe, M. B. N., Christensen, Liv von Voss, Dal, Jenna Elizabeth Hunt, Gadgaard, S., Gasbjerg, Lærke Smidt, Holst, Jens Juul, Kissow, Hannelouise, Hartmann, Bolette & Rosenkilde, Mette, Jan 2023, In: British Journal of Pharmacology. 180, 13, p. 1674-1689

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Biased Signaling of CCL21 and CCL19 Does Not Rely on N-Terminal Differences, but Markedly on the Chemokine Core Domains and Extracellular Loop 2 of CCR7

    Jørgensen, Astrid Sissel, Larsen, Olav, Uetz-von Allmen, E., Lückmann, Michael, Legler, D. F., Frimurer, Thomas Michael, Veldkamp, C. T., Hjortø, Gertrud Malene & Rosenkilde, Mette, 2019, In: Frontiers in Immunology. 10, 14 p., 2156.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Biased agonism and allosteric modulation of GPR183- a 7TM receptor also known as EBV-induced EBI2

    Daugvilaite, V., Madsen, C. M., Lückmann, Michael, Castello Echeverria, C., Sailer, A. W., Frimurer, Thomas Michael, Rosenkilde, Mette & Benned-Jensen, T., 2017, In: British Journal of Pharmacology. 174, 13, p. 2031–2042

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Biased and Constitutive Signaling in the CC-Chemokine Receptor CCR5 by manipulating the Interface between Transmembrane Helix 6 and 7

    Steen, A., Thiele, S., Guo, D., Gasbjerg, Lærke Smidt, Frimurer, Thomas Michael & Rosenkilde, Mette, 3 May 2013, In: Journal of Biological Chemistry. 288, 18, p. 12511-12521 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Biased signaling of lipids and allosteric actions of synthetic molecules for GPR119

    Hassing, H. A., Fares, S., Larsen, Olav, Pad, H., Pedersen, M. H., Jones, R. M., Schwartz, Thue W., Hansen, Harald S. & Rosenkilde, Mette, 26 Aug 2016, In: Biochemical Pharmacology. 119, 1, p. 66-75 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Biases in the perceived timing of perisaccadic perceptual and motor events

    Yarrow, K., Whiteley, Louise, Haggard, P. & Rothwell, J. C., 2006, In: Attention, Perception & Psychophysics. 68, 7, p. 1217-26 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Bidirectional GPR119 agonism requires peptide YY and glucose for activity in mouse and human colon mucosa

    Tough, I. R., Forbes, S., Herzog, H., Jones, R. M., Schwartz, Thue W. & Cox, H. M., 1 Apr 2018, In: Endocrinology. 159, 4, p. 1704-1717

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Bidirectional manipulation of gene expression in adipocytes using CRISPRa and siRNA

    Lundh, M., Plucinska, Kaja, Isidor, Marie Sophie, Petersen, P. S. S. & Emanuelli, Brice, Oct 2017, In: Molecular Metabolism. 6, 10, p. 1313-1320 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Bifidobacteria or fiber protects against diet-induced microbiota-mediated colonic mucus deterioration

    Schroeder, B. O., Birchenough, G. M. H., Ståhlman, M., Arike, L., Johansson, M. E. V., Hansson, G. C. & Bäckhed, F., 2018, In: Cell Host & Microbe. 23, 1, p. 27-40 + e1-e7 22 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Bile Acids Trigger GLP-1 Release Predominantly by Accessing Basolaterally Located G Protein-Coupled Bile Acid Receptors

    Brighton, C. A., Rievaj, J., Kuhre, Rune Ehrenreich, Glass, L. L., Schoonjans, K., Holst, Jens Juul, Gribble, F. M. & Reimann, F., 2015, In: Endocrinology. 156, 11, p. 3961-1370 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Bile Modulates Secretion of Incretins and Insulin: A Study of Human Extrahepatic Cholestasis

    Mezza, T., Moffa, S., Ferraro, P. M., Quero, G., Capece, U., Carfi, A., Cefalo, C. M. A., Cinti, F., Sorice, G. P., Impronta, F., Mari, A., Pontecorvi, A., Alfieri, S., Holst, Jens Juul & Giaccari, A., 2019, In: Journal of Clinical Endocrinology & Metabolism. 104, 7, p. 2685-2694

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Bile acid mediated effects on gut integrity and performance of early-weaned piglets

    de Diego-Cabero, N., Mereu, A., Menoyo, D., Holst, Jens Juul & Ipharraguerre, I. R., 2015, In: B M C Veterinary Research. 11, 1, p. 1-8 8 p., 111.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Bile acid sequestrants for glycemic control in patients with type 2 diabetes: A systematic review with meta-analysis of randomized controlled trials

    Hansen, M., Sonne, David Peick, Mikkelsen, K. H., Gluud, Lise Lotte, Vilsbøll, Tina & Knop, Filip Krag, May 2017, In: Journal of Diabetes and its Complications. 31, 5, p. 918-927 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Bile acid-farnesoid X receptor-fibroblast growth factor 19 axis in patients with short bowel syndrome: The randomized, glepaglutide phase 2 trial

    Hvistendahl, M. K., Naimi, R. M., Hansen, S. H., Rehfeld, Jens Frederik, Kissow, Hannelouise, Pedersen, Jens, Dragsted, Lars Ove, Sonne, D. P., Knop, Filip Krag & Jeppesen, Palle Bekker, 2022, In: Journal of Parenteral and Enteral Nutrition. 46, 4, p. 923-935 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review